Interleukin-6 Protects against Fas-mediated Death by Establishing a Critical Level of Anti-apoptotic Hepatic Proteins FLIP, Bcl-2, and Bcl-xL

Journal of Biological Chemistry

Volumn 276, Issue 28, 2001, Pages 26605-26613

  Kovalovich, Kellen ^a   Li, Wei ^a   DeAngelis, Robert ^a   Greenbaum, Linda E ^a   Ciliberto, Gennaro ^b   Taub, Rebecca ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b IRBM   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CHEMICAL ACTIVATION; ENZYME INHIBITION; PROTEINS;

APOPTOSIS; HEPATOCYTES;

BIOCHEMISTRY;

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CARBON TETRACHLORIDE; CASPASE 3; CASPASE 8; FAS LIGAND; FLICE INHIBITORY PROTEIN; GENOMIC DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MESSENGER RNA; MONOCLONAL ANTIBODY; PROTEIN BCL 2; PROTEIN BCL XL; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; STAT3 PROTEIN; TUMOR NECROSIS FACTOR; BCL2L1 PROTEIN, MOUSE; CARRIER PROTEIN; CFLAR PROTEIN, MOUSE; FAS ANTIGEN; PROTEIN BCL X; SIGNAL PEPTIDE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL MODEL; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DEATH; DNA BINDING; ENZYME ACTIVATION; IMMUNOBLOTTING; LIVER CELL CULTURE; LIVER FUNCTION TEST; LIVER INJURY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; TOXIC HEPATITIS; TRANSCRIPTION REGULATION; ANIMAL; DRUG EFFECT; LIVER; METABOLISM; PATHOLOGY;

ANIMALIA;

ANIMALS; ANTIGENS, CD95; BCL-X PROTEIN; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL DEATH; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER; MICE; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0035854780     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M100740200     Document Type: Article

References (41)

1. Kondo, T., Suda, T., Fukuyama, H., Adachi, M., and Nagata, S. (1997) Nat. Med. 3, 409-413
2. Tokushige, K., Yamaguchi, N., Ikeda, I., Hashimoto, E., Yamauchi, K., and Hayashi, N. (2000) Am. J. Gastroenterol. 95, 2040-2046
3. Afford, S. C., Randhawa, S., Eliopoulos, A. G., Hubscher, S. G., Young, L. S., and Adams, D. H. (1999) J. Exp. Med. 189, 441-446
4. Ogasawara, J., Watanabe-Fukunaga, R., Adachi, M., Matsuzawa, A., Kasugai, T., Kitamura, Y., Itoh, N., Suda, T., and Nagata, S. (1993) Nature 364, 806-809
5. Adachi, M., Suematsu, S., Kondo, T., Ogasawara, J., Tanaka, T., Yoshida, N., and Nagata, S. (1995) Nat. Genet. 11, 294-300
6. Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., and Taub, R. (1996) Science 274, 1379-1383
7. Kovalovich, K., DeAngelis, R. A., Li, W., Furth, E. E., Ciliberto, G., and Taub, R. (2000) Hepatology 31, 149-159
8. Berger, M. L., Bhatt, H., Combes, B., and Estabrook, R. W. (1986) Hepatology 6, 36-45
9. Slater, T. F. (1966) Nature 209, 36-40
10. Shi, J., Aisaki, K., Ikawa, Y., and Wake, K. (1998) Am. J. Pathol. 153, 515-525
11. Czaja, M. J., Xu, J., and Alt, E. (1995) Gastroenterology 108, 1849-1854
12. Poli, V., Balena, R., Fattori, E., Markatos, A., Yamamoto, M., Tanaka, H., Ciliberto, G., Rodan, G. A., and Costantini, F. (1994) EMBO J. 13, 1189-1196
13. Bluethmann, H., Rothe, J., Schultze, N., Tkachuk, M., and Koebel, P. (1994) J. Leukoc. Biol. 56, 565-570
14. Kopf, M., Baumann, H., Freer, G., Freudenberg, M., Lamers, M., Kishimoto, T., Zinkernagel, R., Bluethmann, H., and Kohler, G. (1994) Nature 368, 339-342
15. Fattori, E., Cappelletti, M., Costa, P., Sellitto, C., Cantoni, L., Carelli, M., Faggioni, R., Fantuzzi, G., Ghezzi, P., and Poli, V. (1994) J. Exp. Med. 180, 1243-1250
16. Rouquet, N., Pages, J. C., Molina, T., Briand, P., and Joulin, V. (1996) Curr. Biol. 6, 1192-1195
17. Redondo, C., Flores, I., Gonzalez, A., Nagata, S., Carrera, A. C., Merida, I., and Martinez, A. C. (1996) J. Clin. Invest. 98, 1245-1252
18. Gorski, K., Carneiro, M., and Schibler, U. (1986) Cell 47, 767-776
19. Taub, R., Roy, A., Dieter, R., and Koontz, J. (1987) J. Biol. Chem. 262, 10893-10897
20. Vaux, D. L., and Strasser, A. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 2239-2244
21. Kao, C. Y., Factor, V. M., and Thorgeirsson, S. S. (1996) Biochem. Biophys. Res. Commun. 222, 64-70
22. Hatano, E., Bradham, C. A., Stark, A., Iimuro, Y., Lemasters, J. J., and Brenner, D. A. (2000) J. Biol. Chem. 275, 11814-11823
23. Yin, X. M., Wang, K., Gross, A., Zhao, Y., Zinkel, S., Klocke, B., Roth, K. A., and Korsmeyer, S. J. (1999) Nature 400, 886-891
24. Irmler, M., Thome, M., Hahne, M., Schneider, P., Hofmann, K., Steiner, V., Bodmer, J. L., Schroter, M., Burns, K., Mattmann, C., Rimoldi, D., French, L. E., and Tschopp, J. (1997) Nature 388, 190-195
25. Yamada, Y., Kirillova, I., Peschon, J. J., and Fausto, N. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 1441-1446
26. Xu, Y., Bialik, S., Jones, B. E., Iimuro, Y., Kitsis, R. N., Srinivasan, A., Brenner, D. A., and Czaja, M. J. (1998) Am. J. Physiol. 275, C1058-C1066
27. Hellerbrand, C., Jobin, C., Iimuro, Y., Licato, L., Sartor, R. B., and Brenner, D. A. (1998) Hepatology 27, 1285-1295
28. Beg, A. A., Sha, W. C., Bronson, R. T., Ghosh, S., and Baltimore, D. (1995) Nature 376, 167-170
29. Iimuro, Y., Nishiura, T., Hellerbrand, C., Behrns, K. E., Schoonhoven, R., Grisham, J. W., and Brenner, D. A. (1998) J. Clin. Invest. 101, 802-811
30. Fukada, T., Hibi, M., Yamanaka, Y., Takahashi-Tezuka, M., Fujitani, Y., Yamaguchi, T., Nakajima, K., and Hirano, T. (1996) Immunity 5, 449-460
31. Gross, A., McDonnell, J. M., and Korsmeyer, S. J. (1999) Genes Dev. 13, 1899-1911
32. Li, H., Zhu, H., Xu, C. J., and Yuan, J. (1998) Cell 94, 491-501
33. Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998) Cell 94, 481-490
34. Boesen-de Cock, J. G., Tepper, A. D., de Vries, E., van Blitterswijk, W. J., and Borst, J. (1999) J. Biol. Chem. 274, 14255-14261
35. Hu, S., Vincenz, C., Ni, J., Gentz, R., and Dixit, V. M. (1997) J. Biol. Chem. 272, 17255-17257
36. Djerbi, M., Screpanti, V., Catrina, A. I., Bogen, B., Biberfeld, P., and Grandien, A. (1999) J. Exp. Med. 190, 1025-1032
37. Gabay, C., and Kushner, I. (1999) N. Engl. J. Med. 340, 448-454
38. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Shevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827
39. Bradham, C. A., Qian, T., Streetz, K., Trautwein, C., Brenner, D. A., and Lemasters, J. J. (1998) Mol. Cell. Biol. 18, 6353-6364
40. Janicke, R. U., Sprengart, M. L., Wati, M. R., and Porter, A. G. (1998) J. Biol. Chem. 273, 9357-9360
41. Pan, G., O'Rourke, K., and Dixit, V. M. (1998) J. Biol. Chem. 273, 5841-5845