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Volumn 319, Issue 1-2, 2010, Pages 30-38

Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes

Author keywords

Akt2; Glucose uptake; Insulin action; Smad5

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 1A; BONE MORPHOGENETIC PROTEIN RECEPTOR 1B; DEXAMETHASONE; INSULIN; PHOSPHATIDATE PHOSPHATASE; PROTEIN KINASE B BETA; SMAD5 PROTEIN;

EID: 77249137169     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2010.01.003     Document Type: Article
Times cited : (15)

References (46)
  • 3
    • 1542781732 scopus 로고    scopus 로고
    • Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B
    • Bae S.S., Cho H., Mu J., and Birnbaum M.J. Isoform-specific regulation of insulin-dependent glucose uptake by Akt/protein kinase B. J. Biol. Chem. 278 (2003) 49530-49536
    • (2003) J. Biol. Chem. , vol.278 , pp. 49530-49536
    • Bae, S.S.1    Cho, H.2    Mu, J.3    Birnbaum, M.J.4
  • 4
    • 0022373605 scopus 로고
    • Distinct biologically active receptors for insulin, insulin-like growth factor I, and insulin-like growth factor II in cultured skeletal muscle cells
    • Beguinot F., Kahn C.R., Moses A.C., and Smith R.J. Distinct biologically active receptors for insulin, insulin-like growth factor I, and insulin-like growth factor II in cultured skeletal muscle cells. J. Biol. Chem. 260 (1985) 15892-15898
    • (1985) J. Biol. Chem. , vol.260 , pp. 15892-15898
    • Beguinot, F.1    Kahn, C.R.2    Moses, A.C.3    Smith, R.J.4
  • 6
    • 33745668478 scopus 로고    scopus 로고
    • siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle
    • Bouzakri K., Zachrisson A., Al-Khalili L., Zhang B.B., Koistinen H.A., Krook A., and Zierath J.R. siRNA-based gene silencing reveals specialized roles of IRS-1/Akt2 and IRS-2/Akt1 in glucose and lipid metabolism in human skeletal muscle. Cell Metab. 4 (2006) 89-96
    • (2006) Cell Metab. , vol.4 , pp. 89-96
    • Bouzakri, K.1    Zachrisson, A.2    Al-Khalili, L.3    Zhang, B.B.4    Koistinen, H.A.5    Krook, A.6    Zierath, J.R.7
  • 8
    • 0037381535 scopus 로고    scopus 로고
    • Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance
    • Brozinick Jr. J.T., Robert B.R., and Dohm G.L. Defective signaling through Akt-2 and -3 but not Akt-1 in insulin-resistant human skeletal muscle: potential role in insulin resistance. Diabetes 52 (2003) 935-941
    • (2003) Diabetes , vol.52 , pp. 935-941
    • Brozinick Jr., J.T.1    Robert, B.R.2    Dohm, G.L.3
  • 10
    • 57349200474 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein-9 expression and processing by insulin, glucose, and glucocorticoids: possible candidate for hepatic insulin-sensitizing substance
    • Caperuto L.C., Anhê G.F., Cambiaghi T.D., Akamine E.H., do Carmo Buonfiglio D., Cipolla-Neto J., Curi R., and Bordin S. Modulation of bone morphogenetic protein-9 expression and processing by insulin, glucose, and glucocorticoids: possible candidate for hepatic insulin-sensitizing substance. Endocrinology 149 (2008) 6326-6335
    • (2008) Endocrinology , vol.149 , pp. 6326-6335
    • Caperuto, L.C.1    Anhê, G.F.2    Cambiaghi, T.D.3    Akamine, E.H.4    do Carmo Buonfiglio, D.5    Cipolla-Neto, J.6    Curi, R.7    Bordin, S.8
  • 13
    • 0035914388 scopus 로고    scopus 로고
    • Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice
    • Cho H., Thorvaldsen J.L., Chu Q., Feng F., and Birnbaum M.J. Akt1/PKBalpha is required for normal growth but dispensable for maintenance of glucose homeostasis in mice. J. Biol. Chem. 276 (2001) 38349-38352
    • (2001) J. Biol. Chem. , vol.276 , pp. 38349-38352
    • Cho, H.1    Thorvaldsen, J.L.2    Chu, Q.3    Feng, F.4    Birnbaum, M.J.5
  • 14
    • 33847369980 scopus 로고    scopus 로고
    • Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells
    • David L., Mallet C., Mazerbourg S., Feige J.J., and Bailly S. Identification of BMP9 and BMP10 as functional activators of the orphan activin receptor-like kinase 1 (ALK1) in endothelial cells. Blood 109 (2007) 1953-1961
    • (2007) Blood , vol.109 , pp. 1953-1961
    • David, L.1    Mallet, C.2    Mazerbourg, S.3    Feige, J.J.4    Bailly, S.5
  • 15
    • 33750380920 scopus 로고    scopus 로고
    • Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies
    • Dummler B., Tschopp O., Hynx D., Yang Z.Z., Dirnhofer S., and Hemmings B.A. Life with a single isoform of Akt: mice lacking Akt2 and Akt3 are viable but display impaired glucose homeostasis and growth deficiencies. Mol. Cell Biol. 26 (2006) 8042-8051
    • (2006) Mol. Cell Biol. , vol.26 , pp. 8042-8051
    • Dummler, B.1    Tschopp, O.2    Hynx, D.3    Yang, Z.Z.4    Dirnhofer, S.5    Hemmings, B.A.6
  • 16
    • 0032549222 scopus 로고    scopus 로고
    • Dexamethasone stimulates the expression of GLUT1 and GLUT4 proteins via different signalling pathways in L6 skeletal muscle cells
    • Ewart H.S., Somwar R., and Klip A. Dexamethasone stimulates the expression of GLUT1 and GLUT4 proteins via different signalling pathways in L6 skeletal muscle cells. FEBS Lett. 425 (1998) 179-183
    • (1998) FEBS Lett. , vol.425 , pp. 179-183
    • Ewart, H.S.1    Somwar, R.2    Klip, A.3
  • 18
    • 0026762722 scopus 로고
    • Role of glucose transporters in glucocorticoid-induced insulin resistance. GLUT4 isoform in rat skeletal muscle is not decreased by dexamethasone
    • Haber R.S., and Weinstein S.P. Role of glucose transporters in glucocorticoid-induced insulin resistance. GLUT4 isoform in rat skeletal muscle is not decreased by dexamethasone. Diabetes 41 (1992) 728-735
    • (1992) Diabetes , vol.41 , pp. 728-735
    • Haber, R.S.1    Weinstein, S.P.2
  • 19
    • 58249109567 scopus 로고    scopus 로고
    • Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes
    • Ikubo M., Wada T., Fukui K., Ishiki M., Ishihara H., Asano T., Tsuneki H., and Sasaoka T. Impact of lipid phosphatases SHIP2 and PTEN on the time- and Akt-isoform-specific amelioration of TNF-alpha-induced insulin resistance in 3T3-L1 adipocytes. Am. J. Physiol. Endocrinol. Metab. 296 (2009) E157-E164
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.296
    • Ikubo, M.1    Wada, T.2    Fukui, K.3    Ishiki, M.4    Ishihara, H.5    Asano, T.6    Tsuneki, H.7    Sasaoka, T.8
  • 22
    • 0036732838 scopus 로고    scopus 로고
    • Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis
    • Katagiri T., Imada M., Yanai T., Suda T., Takahashi N., and Kamijo R. Identification of a BMP-responsive element in Id1, the gene for inhibition of myogenesis. Genes Cells 7 (2002) 949-960
    • (2002) Genes Cells , vol.7 , pp. 949-960
    • Katagiri, T.1    Imada, M.2    Yanai, T.3    Suda, T.4    Takahashi, N.5    Kamijo, R.6
  • 23
    • 67651237066 scopus 로고    scopus 로고
    • The many ways to regulate glucose transporter 4
    • Klip A. The many ways to regulate glucose transporter 4. Appl. Physiol. Nutr. Metab. 34 (2009) 481-487
    • (2009) Appl. Physiol. Nutr. Metab. , vol.34 , pp. 481-487
    • Klip, A.1
  • 24
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • Korchynskyi O., and ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J. Biol. Chem. 277 (2002) 4883-4891
    • (2002) J. Biol. Chem. , vol.277 , pp. 4883-4891
    • Korchynskyi, O.1    ten Dijke, P.2
  • 25
    • 0032752551 scopus 로고    scopus 로고
    • The HISS story overview: a novel hepatic neurohumoral regulation of peripheral insulin sensitivity in health and diabetes
    • Lautt W.W. The HISS story overview: a novel hepatic neurohumoral regulation of peripheral insulin sensitivity in health and diabetes. Can. J. Physiol. Pharmacol. 77 (1999) 553-562
    • (1999) Can. J. Physiol. Pharmacol. , vol.77 , pp. 553-562
    • Lautt, W.W.1
  • 26
    • 0033822836 scopus 로고    scopus 로고
    • Differentiation of myoblasts in serum-free media: effects of modified media are cell line-specific
    • Lawson M.A., and Purslow P.P. Differentiation of myoblasts in serum-free media: effects of modified media are cell line-specific. Cells Tissues Organs 167 (2000) 130-137
    • (2000) Cells Tissues Organs , vol.167 , pp. 130-137
    • Lawson, M.A.1    Purslow, P.P.2
  • 28
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama T., and Dixon J.E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem. 273 (1998) 13375-13378
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 29
  • 30
    • 17844401269 scopus 로고    scopus 로고
    • Akt2 is essential for the full effect of calorie restriction on insulin-stimulated glucose uptake in skeletal muscle
    • McCurdy C.E., and Cartee G.D. Akt2 is essential for the full effect of calorie restriction on insulin-stimulated glucose uptake in skeletal muscle. Diabetes 54 (2005) 1349-1356
    • (2005) Diabetes , vol.54 , pp. 1349-1356
    • McCurdy, C.E.1    Cartee, G.D.2
  • 31
    • 0034674782 scopus 로고    scopus 로고
    • Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver
    • Miller A.F., Harvey S.A., Thies R.S., and Olson M.S. Bone morphogenetic protein-9. An autocrine/paracrine cytokine in the liver. J. Biol. Chem. 275 (2000) 17937-17945
    • (2000) J. Biol. Chem. , vol.275 , pp. 17937-17945
    • Miller, A.F.1    Harvey, S.A.2    Thies, R.S.3    Olson, M.S.4
  • 32
    • 0025916110 scopus 로고
    • Differential expression of the GLUT1 and GLUT4 glucose transporters during differentiation of L6 muscle cells
    • Mitsumoto Y., Burdett E., Grant A., and Klip A. Differential expression of the GLUT1 and GLUT4 glucose transporters during differentiation of L6 muscle cells. Biochem. Biophys. Res. Commun. 175 (1991) 652-659
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 652-659
    • Mitsumoto, Y.1    Burdett, E.2    Grant, A.3    Klip, A.4
  • 33
    • 0037167519 scopus 로고    scopus 로고
    • Id: a target of BMP signaling
    • Miyazono K., and Miyazawa K. Id: a target of BMP signaling. Sci. STKE 151 (2002) PE40
    • (2002) Sci. STKE , vol.151
    • Miyazono, K.1    Miyazawa, K.2
  • 34
    • 41549153181 scopus 로고    scopus 로고
    • C/EBPs: recipients of extracellular signals through proteome modulation
    • Nerlov C. C/EBPs: recipients of extracellular signals through proteome modulation. Curr. Opin. Cell Biol. 20 (2008) 180-185
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 180-185
    • Nerlov, C.1
  • 36
    • 0034134245 scopus 로고    scopus 로고
    • Overexpression of wild-type Akt1 promoted insulin-stimulated p70S6 kinase (p70S6K) activity and affected GSK3 beta regulation, but did not promote insulin-stimulated GLUT4 translocation or glucose transport in L6 myotubes
    • Noda S., Kishi K., Yuasa T., Hayashi H., Ohnishi T., Miyata I., Nishitani H., and Ebina Y. Overexpression of wild-type Akt1 promoted insulin-stimulated p70S6 kinase (p70S6K) activity and affected GSK3 beta regulation, but did not promote insulin-stimulated GLUT4 translocation or glucose transport in L6 myotubes. J. Med. Invest. 47 (2000) 47-55
    • (2000) J. Med. Invest. , vol.47 , pp. 47-55
    • Noda, S.1    Kishi, K.2    Yuasa, T.3    Hayashi, H.4    Ohnishi, T.5    Miyata, I.6    Nishitani, H.7    Ebina, Y.8
  • 37
    • 62149108988 scopus 로고    scopus 로고
    • Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation
    • Rotwein P., and Wilson E.M. Distinct actions of Akt1 and Akt2 in skeletal muscle differentiation. J. Cell Physiol. 219 (2009) 503-511
    • (2009) J. Cell Physiol. , vol.219 , pp. 503-511
    • Rotwein, P.1    Wilson, E.M.2
  • 38
    • 0035947593 scopus 로고    scopus 로고
    • Filamin associates with Smads and regulates transforming growth factor-beta signaling
    • Sasaki A., Masuda Y., Ohta Y., Ikeda K., and Watanabe K. Filamin associates with Smads and regulates transforming growth factor-beta signaling. J. Biol. Chem. 276 (2001) 17871-17877
    • (2001) J. Biol. Chem. , vol.276 , pp. 17871-17877
    • Sasaki, A.1    Masuda, Y.2    Ohta, Y.3    Ikeda, K.4    Watanabe, K.5
  • 41
    • 33244464562 scopus 로고    scopus 로고
    • Critical nodes in signalling pathways: insights into insulin action
    • Taniguchi C.M., Emanuelli B., and Kahn C.R. Critical nodes in signalling pathways: insights into insulin action. Nat. Rev. Mol. Cell Biol. 7 (2006) 85-96
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 85-96
    • Taniguchi, C.M.1    Emanuelli, B.2    Kahn, C.R.3
  • 42
    • 0034907579 scopus 로고    scopus 로고
    • Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles
    • Tong P., Khayat Z.A., Huang C., Patel N., Ueyama A., and Klip A. Insulin-induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles. J. Clin. Invest. 108 (2001) 371-381
    • (2001) J. Clin. Invest. , vol.108 , pp. 371-381
    • Tong, P.1    Khayat, Z.A.2    Huang, C.3    Patel, N.4    Ueyama, A.5    Klip, A.6
  • 43
    • 42049114841 scopus 로고    scopus 로고
    • Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer
    • Tsuchida K., Nakatani M., Uezumi A., Murakami T., and Cui X. Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer. Endocr. J. 55 (2008) 11-21
    • (2008) Endocr. J. , vol.55 , pp. 11-21
    • Tsuchida, K.1    Nakatani, M.2    Uezumi, A.3    Murakami, T.4    Cui, X.5
  • 44
    • 0035504887 scopus 로고    scopus 로고
    • Intracellular BMP signaling regulation in vertebrates: pathway or network?
    • von Bubnoff A., and Cho K.W. Intracellular BMP signaling regulation in vertebrates: pathway or network?. Dev. Biol. 239 (2001) 1-14
    • (2001) Dev. Biol. , vol.239 , pp. 1-14
    • von Bubnoff, A.1    Cho, K.W.2
  • 46
    • 0037862003 scopus 로고    scopus 로고
    • New intracellular components of bone morphogenetic protein/Smad signaling cascades
    • Zwijsen A., Verschueren K., and Huylebroeck D. New intracellular components of bone morphogenetic protein/Smad signaling cascades. FEBS Lett. 546 (2003) 133-139
    • (2003) FEBS Lett. , vol.546 , pp. 133-139
    • Zwijsen, A.1    Verschueren, K.2    Huylebroeck, D.3


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