-
1
-
-
0000280462
-
Deux cas d'atrophie musculaire progressive avec lesions de la substance grise et des faisceaux anterolateraux de la moelle epiniere
-
Charcot, J.M.; Joffroy, A. Deux cas d'atrophie musculaire progressive avec lesions de la substance grise et des faisceaux anterolateraux de la moelle epiniere. Arch. Physiol., 1869, 2, 354.
-
(1869)
Arch. Physiol
, vol.2
, pp. 354
-
-
Charcot, J.M.1
Joffroy, A.2
-
2
-
-
0037425321
-
Motor neurone disease: A pandora's box
-
Kiernan, M.C. Motor neurone disease: a pandora's box. Med. J. Aust., 2003, 178, 311-2.
-
(2003)
Med. J. Aust
, vol.178
, pp. 311-312
-
-
Kiernan, M.C.1
-
3
-
-
0026565355
-
Amyotrophic lateral sclerosis (ALS): A phylogenetic disease of the corticomotoneuron?
-
Eisen, A.; Kim, S.; Pant, B. Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotoneuron? Muscle Nerve, 1992, 15, 219-24.
-
(1992)
Muscle Nerve
, vol.15
, pp. 219-224
-
-
Eisen, A.1
Kim, S.2
Pant, B.3
-
4
-
-
0027265313
-
The natural history of amyotrophic lateral sclerosis
-
Ringel, S.P.; Murphy, J.R.; Alderson, M.K.; Bryan, W, England, J.D.; Miller, R.G.; Petajan, J.H.; Smith, S.A.; Roelofs, R.I.; Ziter, F.; Lee, M.Y.; Brinkmann, J.R.; Almada, A.; Gappmaier, E.; Graves, J.; Herbelin, L.; Mendoza, M.; Mylar, D.; Smith, P.; Yu, P. The natural history of amyotrophic lateral sclerosis. Neurology, 1993, 43, 1316-22.
-
(1993)
Neurology
, vol.43
, pp. 1316-1322
-
-
Ringel, S.P.1
Murphy, J.R.2
Alderson, M.K.3
Bryan, W.4
England, J.D.5
Miller, R.G.6
Petajan, J.H.7
Smith, S.A.8
Roelofs, R.I.9
Ziter, F.10
Lee, M.Y.11
Brinkmann, J.R.12
Almada, A.13
Gappmaier, E.14
Graves, J.15
Herbelin, L.16
Mendoza, M.17
Mylar, D.18
Smith, P.19
Yu, P.20
more..
-
5
-
-
34249750511
-
Prognosis of amyotrophic lateral sclerosis with respiratory onset
-
Shoesmith, C.L.; Findlater, K.; Rowe, A.; Strong, M.J. Prognosis of amyotrophic lateral sclerosis with respiratory onset. J. Neurol. Neurosurg. Psychiatry, 2007, 78, 629-31.
-
(2007)
J. Neurol. Neurosurg. Psychiatry
, vol.78
, pp. 629-631
-
-
Shoesmith, C.L.1
Findlater, K.2
Rowe, A.3
Strong, M.J.4
-
6
-
-
0023128148
-
Amyotrophic lateral sclerosis
-
Caroscio, J.T.; Mulvihill, M.N.; Sterling, R.; Abrams, B. Amyotrophic lateral sclerosis. Its natural history. Neurol. Clin., 1987, 5, 1-8.
-
(1987)
Neurol. Clin
, vol.5
, pp. 1-8
-
-
Caroscio, J.T.1
Mulvihill, M.N.2
Sterling, R.3
Abrams, B.4
-
7
-
-
33751250197
-
Genetics of familial and sporadic amyotrophic lateral sclerosis
-
Gros-Louis, F.; Gaspar, C.; Rouleau, G.A. Genetics of familial and sporadic amyotrophic lateral sclerosis. Biochim. Biophys. Acta, 2006, 1762, 956-72.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 956-972
-
-
Gros-Louis, F.1
Gaspar, C.2
Rouleau, G.A.3
-
8
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
-
Pasinelli, P.; Brown, R.H. Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci., 2006, 7, 710-23.
-
(2006)
Nat. Rev. Neurosci
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
9
-
-
0036887265
-
Amyotrophic lateral sclerosis: Pathogenesis, differential diagnoses, and potential interventions
-
Patel, S.A.; Maragakis, N.J. Amyotrophic lateral sclerosis: pathogenesis, differential diagnoses, and potential interventions. J. Spinal Cord Med., 2002, 25, 262-73.
-
(2002)
J. SpiNal Cord Med
, vol.25
, pp. 262-273
-
-
Patel, S.A.1
Maragakis, N.J.2
-
10
-
-
34249670157
-
Glia cells in amyotrophic lateral sclerosis: New clues to understanding an old disease?
-
Neusch, C.; Bahr, M.; Schneider-Gold, C. Glia cells in amyotrophic lateral sclerosis: new clues to understanding an old disease? Muscle Nerve, 2007, 35, 712-24.
-
(2007)
Muscle Nerve
, vol.35
, pp. 712-724
-
-
Neusch, C.1
Bahr, M.2
Schneider-Gold, C.3
-
11
-
-
34248149517
-
Amyotrophic lateral sclerosis: All roads lead to Rome
-
Gonzalez de Aguilar, J.L.; Echaniz-Laguna, A.; Fergani, A.; Rene, F.; Meininger, V.; Loeffler, JP, Dupuis, L. Amyotrophic lateral sclerosis: all roads lead to Rome. J. Neurochem., 2007, 101, 1153-60.
-
(2007)
J. Neurochem
, vol.101
, pp. 1153-1160
-
-
Gonzalez de Aguilar, J.L.1
Echaniz-Laguna, A.2
Fergani, A.3
Rene, F.4
Meininger, V.5
Loeffler, J.P.6
Dupuis, L.7
-
12
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa, M.; Arai, T.; Nonaka, T.; Kametani, F.; Yoshida, M.; Hashizume, Y.; Beach, T.G.; Buratti, E.; Baralle, F.; Morita, M.; Nakano, I.; Oda, T.; Tsuchiya, K.; Akiyama, H. Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann. Neurol., 2008, 64, 60-70.
-
(2008)
Ann. Neurol
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
Beach, T.G.7
Buratti, E.8
Baralle, F.9
Morita, M.10
Nakano, I.11
Oda, T.12
Tsuchiya, K.13
Akiyama, H.14
-
13
-
-
0029753270
-
The pharmacology and mechanism of action of riluzole
-
Doble, A. The pharmacology and mechanism of action of riluzole. Neurology, 1996, 47, S233-41.
-
(1996)
Neurology
, vol.47
, pp. 233-241
-
-
Doble, A.1
-
14
-
-
0036787803
-
Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis
-
Heath, P.R.; Shaw, P.J. Update on the glutamatergic neurotransmitter system and the role of excitotoxicity in amyotrophic lateral sclerosis. Muscle Nerve, 2002, 26, 438-58.
-
(2002)
Muscle Nerve
, vol.26
, pp. 438-458
-
-
Heath, P.R.1
Shaw, P.J.2
-
15
-
-
66749154197
-
Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis
-
Foran, E.; Trotti, D. Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis. Antioxid. Redox. Signal, 2009, 11, 1587-602.
-
(2009)
Antioxid. Redox. Signal
, vol.11
, pp. 1587-1602
-
-
Foran, E.1
Trotti, D.2
-
16
-
-
0030812843
-
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1
-
Tanaka, K.; Watase, K.; Manabe, T.; Yamada K.;, Watanabe M.; Takahashi K.; Iwama H.; Nishikawa T.; Ichihara N.; Kikuchi T.; Okuyama S.; Kawashima N.; Hori S.; Takimoto M.; Wada K. Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science, 1997, 276, 1699-1702.
-
(1997)
Science
, vol.276
, pp. 1699-1702
-
-
Tanaka, K.1
Watase, K.2
Manabe, T.3
Yamada, K.4
Watanabe, M.5
Takahashi, K.6
Iwama, H.7
Nishikawa, T.8
Ichihara, N.9
Kikuchi, T.10
Okuyama, S.11
Kawashima, N.12
Hori, S.13
Takimoto, M.14
Wada, K.15
-
17
-
-
0029091514
-
Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: Immunogold evidence from hippocampal slice cultures
-
Laake, J.H.; Slyngstad, T.A.; Haug, F.M.; Ottersen, O.P. Glutamine from glial cells is essential for the maintenance of the nerve terminal pool of glutamate: immunogold evidence from hippocampal slice cultures. J. Neurochem., 1995, 65, 871-81.
-
(1995)
J. Neurochem
, vol.65
, pp. 871-881
-
-
Laake, J.H.1
Slyngstad, T.A.2
Haug, F.M.3
Ottersen, O.P.4
-
18
-
-
0025299819
-
Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis
-
Rothstein, J.D.; Tsai, G.; Kuncl, R.W.; Clawson, L.; Cornblath, D.R.; Drachman, D.B.; Pestronk, A.; Stauch, B.L.; J.T. C. Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis. Ann. Neurol., 1990, 28, 18-25.
-
(1990)
Ann. Neurol
, vol.28
, pp. 18-25
-
-
Rothstein, J.D.1
Tsai, G.2
Kuncl, R.W.3
Clawson, L.4
Cornblath, D.R.5
Drachman, D.B.6
Pestronk, A.7
Stauch, B.L.8
-
19
-
-
34548752918
-
Intrathecal infusion of a Ca2+-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS
-
Yin, H.Z.; Tang, D.T.; Weiss, J.H. Intrathecal infusion of a Ca2+-permeable AMPA channel blocker slows loss of both motor neurons and of the astrocyte glutamate transporter, GLT-1 in a mutant SOD1 rat model of ALS. Exp. Neurol., 2007, 207, 177-85.
-
(2007)
Exp. Neurol
, vol.207
, pp. 177-185
-
-
Yin, H.Z.1
Tang, D.T.2
Weiss, J.H.3
-
20
-
-
0029030610
-
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
-
Rothstein, J.D.; Van Kammen, M.; Levey, A.I.; Martin, L.J.; Kuncl, R.W. Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann. Neurol., 1995, 38, 73-84.
-
(1995)
Ann. Neurol
, vol.38
, pp. 73-84
-
-
Rothstein, J.D.1
van Kammen, M.2
Levey, A.I.3
Martin, L.J.4
Kuncl, R.W.5
-
21
-
-
0026597010
-
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
-
Rothstein, J.D.; Martin, L.J.; Kuncl, R.W. Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N. Engl. J. Med., 1992, 326, 1464-68.
-
(1992)
N. Engl. J. Med
, vol.326
, pp. 1464-1468
-
-
Rothstein, J.D.1
Martin, L.J.2
Kuncl, R.W.3
-
22
-
-
13344286293
-
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate
-
Rothstein, J.D.; Dykes-Hoberg, M.; Pardo, C.A.; Bristol, L.A.; Jin, L.; Kuncl, R.W.; Kanai, Y.; Hediger, M.A.; Wang, Y.; Schielke, J.P.; Welty, D.F. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron, 1996, 16, 675-86.
-
(1996)
Neuron
, vol.16
, pp. 675-686
-
-
Rothstein, J.D.1
Dykes-Hoberg, M.2
Pardo, C.A.3
Bristol, L.A.4
Jin, L.5
Kuncl, R.W.6
Kanai, Y.7
Hediger, M.A.8
Wang, Y.9
Schielke, J.P.10
Welty, D.F.11
-
23
-
-
0031020015
-
Neuronal regulation of glutamate transporter subtype expression in astrocytes
-
Swanson, R.A.; Liu, J.; Miller, J.W.; Rothstein, J.D.; Farrell, K.; A. Stein, B, Longuemare, M.C. Neuronal regulation of glutamate transporter subtype expression in astrocytes. J. Neurosci., 1997, 17, 932-40.
-
(1997)
J. Neurosci
, vol.17
, pp. 932-940
-
-
Swanson, R.A.1
Liu, J.2
Miller, J.W.3
Rothstein, J.D.4
Farrell, K.5
Stein, A.B.6
Longuemare, M.C.7
-
24
-
-
0345269737
-
Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons
-
Rao, S.D.; Yin, H.Z.; Weiss, J.H. Disruption of glial glutamate transport by reactive oxygen species produced in motor neurons. J. Neurosci., 2003, 23, 2627-33.
-
(2003)
J. Neurosci
, vol.23
, pp. 2627-2633
-
-
Rao, S.D.1
Yin, H.Z.2
Weiss, J.H.3
-
25
-
-
0025923461
-
Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition
-
Hollmann, M.; Hartley, M.; Heinemann, S. Ca2+ permeability of KA-AMPA--gated glutamate receptor channels depends on subunit composition. Science, 1991, 252, 851-3.
-
(1991)
Science
, vol.252
, pp. 851-853
-
-
Hollmann, M.1
Hartley, M.2
Heinemann, S.3
-
26
-
-
0036713846
-
GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity
-
Van Damme, P.; Van Den Bosch, L.; Van Houtte, E.; Callewaert, G.; Robberecht, W. GluR2-dependent properties of AMPA receptors determine the selective vulnerability of motor neurons to excitotoxicity. J. Neurophysiol., 2002, 88, 1279-87.
-
(2002)
J. Neurophysiol
, vol.88
, pp. 1279-1287
-
-
van Damme, P.1
Van Den Bosch, L.2
van Houtte, E.3
Callewaert, G.4
Robberecht, W.5
-
27
-
-
2542498984
-
AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo
-
Corona, J.C.; Tapia, R. AMPA receptor activation, but not the accumulation of endogenous extracellular glutamate, induces paralysis and motor neuron death in rat spinal cord in vivo. J. Neurochem., 2004, 89, 988-97.
-
(2004)
J. NeuroChem
, vol.89
, pp. 988-997
-
-
Corona, J.C.1
Tapia, R.2
-
28
-
-
39049161976
-
Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: Implications for excitotoxicity
-
Zhao, P.; Ignacio, S.; Beattie, E.C.; Abood, M.E. Altered presymptomatic AMPA and cannabinoid receptor trafficking in motor neurons of ALS model mice: implications for excitotoxicity. Eur. J. Neurosci., 2008, 27, 572-9.
-
(2008)
Eur. J. Neurosci
, vol.27
, pp. 572-579
-
-
Zhao, P.1
Ignacio, S.2
Beattie, E.C.3
Abood, M.E.4
-
29
-
-
0027946813
-
The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis
-
Maria, E.; Alexianu, B-K.H. The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis. Ann. Neurol., 1994, 36, 846-58.
-
(1994)
Ann. Neurol
, vol.36
, pp. 846-858
-
-
Maria, E.1
Alexianu, B-K.H.2
-
30
-
-
0027210116
-
Parvalbumin and calbindin d-28k in the human motor system and in motor neuron disease
-
Ince, P.; Stout, N.; Shaw, P.; Slade, J.; Hunziker, W.; Heizmann, C.W.; Baimbridge, K.G. Parvalbumin and calbindin d-28k in the human motor system and in motor neuron disease. Neuropathol. Appl. Neurobiol., 1993, 19, 291-9.
-
(1993)
Neuropathol. Appl. Neurobiol
, vol.19
, pp. 291-299
-
-
Ince, P.1
Stout, N.2
Shaw, P.3
Slade, J.4
Hunziker, W.5
Heizmann, C.W.6
Baimbridge, K.G.7
-
31
-
-
0032402093
-
Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms
-
Roy, J.; Minotti, S.; Dong, L.; Figlewicz, D.A.; Durham, H.D. Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms. J. Neurosci., 1998, 18, 9673-84.
-
(1998)
J. Neurosci
, vol.18
, pp. 9673-9684
-
-
Roy, J.1
Minotti, S.2
Dong, L.3
Figlewicz, D.A.4
Durham, H.D.5
-
32
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen, D.R.; Siddique, T.; Patterson, D.; Figlewicz, D.A.; Sapp, P.; Hentati, A.; Donaldson, D.; Goto, J.; O'Regan, J.P.; Deng, H.X.; Rahmani, Z.; Krizus, A.; McKenna-Yasek, D.; Cayabyab, A.; Gaston, S.; Berger, R.; Tanzi, R.E.; Halperin, J.J.; Herzfeldt, B.; Van den Bergh, R.; Hung, W.; Bird, T.; Deng, G.; Mulder, D.W.; Smyth, C.; Laing, N.G.; Soriano, E.; Pericak-Vance, M.A.; Haines, J.; Rouleau, G.A.; Gusella, J.S.; Horvitz, H.R.; Brown, R.H.Jr. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature, 1993, 362, 59-62.
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
Rahmani, Z.11
Krizus, A.12
McKenna-Yasek, D.13
Cayabyab, A.14
Gaston, S.15
Berger, R.16
Tanzi, R.E.17
Halperin, J.J.18
Herzfeldt, B.19
Van den Bergh, R.20
Hung, W.21
Bird, T.22
Deng, G.23
Mulder, D.W.24
Smyth, C.25
Laing, N.G.26
Soriano, E.27
Pericak-Vance, M.A.28
Haines, J.29
Rouleau, G.A.30
Gusella, J.S.31
Horvitz, H.R.32
Brown Jr., R.H.33
more..
-
33
-
-
18544384019
-
Oxidation of tartaric acid in presence of iron
-
Fenton, H.J.H. Oxidation of tartaric acid in presence of iron. J. Chem. Soc, Trans, 1894, 65, 899-910.
-
(1894)
J. Chem. Soc, Trans
, vol.65
, pp. 899-910
-
-
Fenton, H.J.H.1
-
34
-
-
33751003518
-
Oxidative stress in ALS: A mechanism of neurodegeneration and a therapeutic target
-
Barber, S.C.; Mead, R.J.; Shaw, P.J. Oxidative stress in ALS: a mechanism of neurodegeneration and a therapeutic target. Biochim. Biophys. Acta., 2006, 1762, 1051-67.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1051-1067
-
-
Barber, S.C.1
Mead, R.J.2
Shaw, P.J.3
-
35
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation
-
Gurney, M.E.; Haifeng, P.; Chiu, A.Y.; Dal Canto, M.C.; Polchow, C.Y.; Alexander, D.D.; Caliendo, J.; Hentati, A.; Kwon, Y.W.; Deng, H.; Chen, W.; Zhai, P.; Sufit, R.L.; Siddique, T. Motor neuron degeneration in mice that express a human Cu/Zn superoxide dismutase mutation. Science, 1994, 264, 1772-5.
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Haifeng, P.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.10
Chen, W.11
Zhai, P.12
Sufit, R.L.13
Siddique, T.14
-
36
-
-
0030050727
-
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney, M.E.; Cutting, F.B.; Zhai, P.; Doble, A.; Taylor, C.P.; Andrus, P.K.; Hall, E.D. Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis. Ann. Neurol., 1996, 39, 147-57.
-
(1996)
Ann. Neurol
, vol.39
, pp. 147-157
-
-
Gurney, M.E.1
Cutting, F.B.2
Zhai, P.3
Doble, A.4
Taylor, C.P.5
Andrus, P.K.6
Hall, E.D.7
-
37
-
-
0031931578
-
Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis
-
Gurney, M.E.; Fleck, T.J.; Himes, C.S.; Hall, E.D. Riluzole preserves motor function in a transgenic model of familial amyotrophic lateral sclerosis. Neurology, 1998, 50, 62-6.
-
(1998)
Neurology
, vol.50
, pp. 62-66
-
-
Gurney, M.E.1
Fleck, T.J.2
Himes, C.S.3
Hall, E.D.4
-
38
-
-
4644225112
-
Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model
-
Waibel, S.; Reuter, A.; Malessa, S.; Blaugrund, E.; Ludolph, A.C. Rasagiline alone and in combination with riluzole prolongs survival in an ALS mouse model. J. Neurol., 2004, 251, 1080-4.
-
(2004)
J. Neurol
, vol.251
, pp. 1080-1084
-
-
Waibel, S.1
Reuter, A.2
Malessa, S.3
Blaugrund, E.4
Ludolph, A.C.5
-
39
-
-
0027944554
-
Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms
-
Volterra, A.; Trotti, D.; Racagni, G. Glutamate uptake is inhibited by arachidonic acid and oxygen radicals via two distinct and additive mechanisms. Mol. Pharmacol., 1994, 46, 986-92.
-
(1994)
Mol. Pharmacol
, vol.46
, pp. 986-992
-
-
Volterra, A.1
Trotti, D.2
Racagni, G.3
-
40
-
-
0032145886
-
Glutamate transporters are oxidant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol
-
Trotti, D.; Danbolt, N.C.; Volterra, A. Glutamate transporters are oxidant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol. Sci., 1998, 19, 328-34.
-
(1998)
Sci
, vol.19
, pp. 328-334
-
-
Trotti, D.1
Danbolt, N.C.2
Volterra, A.3
-
41
-
-
0013911740
-
Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis
-
Afifi, A.K.; Aleu, F.P.; Goodgold, J.; MacKay, B. Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis. Neurology, 1966, 16, 475-81.
-
(1966)
Neurology
, vol.16
, pp. 475-481
-
-
Afifi, A.K.1
Aleu, F.P.2
Goodgold, J.3
Mackay, B.4
-
42
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
Kong, J.; Xu, Z. Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J. Neurosci., 1998, 18, 3241-50.
-
(1998)
J. Neurosci
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
43
-
-
35548991459
-
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
-
De Vos, K.J.; Chapman, A.L.; Tennant, M.E.; Manser, C.; Tudor, E.L.; Lau, K.F.; Brownlees, J.; Ackerley, S.; Shaw, P.J.; McLoughlin, D.M.; Shaw, C.E.; Leigh, P.N.; Miller, C.C.; Grierson, A.J. Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content. Hum. Mol. Genet., 2007, 16, 2720-8.
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 2720-2728
-
-
de Vos, K.J.1
Chapman, A.L.2
Tennant, M.E.3
Manser, C.4
Tudor, E.L.5
Lau, K.F.6
Brownlees, J.7
Ackerley, S.8
Shaw, P.J.9
McLoughlin, D.M.10
Shaw, C.E.11
Leigh, P.N.12
Miller, C.C.13
Grierson, A.J.14
-
44
-
-
0032504568
-
The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy
-
Lemasters, J.J.; Nieminen, A.L.; Qian, T.; Trost, L.C.; Elmore, S.P.; Nishimura, Y.; Crowe, R.A.; Cascio, W.E.; Bradham, C.A.; Brenner, D.A.; Herman, B. The mitochondrial permeability transition in cell death: A common mechanism in necrosis, apoptosis and autophagy. Biochim. Biophys. Acta, 1998, 1366, 177-96.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 177-196
-
-
Lemasters, J.J.1
Nieminen, A.L.2
Qian, T.3
Trost, L.C.4
Elmore, S.P.5
Nishimura, Y.6
Crowe, R.A.7
Cascio, W.E.8
Bradham, C.A.9
Brenner, D.A.10
Herman, B.11
-
45
-
-
0034655408
-
Cytochrome c release and caspase activation in traumatic axonal injury
-
Buki, A.; Okonkwo, D.O.; Wang, K.K.W.; Povlishock, J.T. Cytochrome c release and caspase activation in traumatic axonal injury. J. Neurosci., 2000, 20, 2825-34.
-
(2000)
J. Neurosci
, vol.20
, pp. 2825-2834
-
-
Buki, A.1
Okonkwo, D.O.2
Wang, K.K.W.3
Povlishock, J.T.4
-
46
-
-
0030581151
-
Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome c
-
Liu, X.; Kim, C.N.; Yang, J.; Jemmerson, R.; Wang, X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell, 1996, 86, 147-57.
-
(1996)
Cell
, vol.86
, pp. 147-157
-
-
Liu, X.1
Kim, C.N.2
Yang, J.3
Jemmerson, R.4
Wang, X.5
-
47
-
-
67649811029
-
The mitochondrial permeability transition pore in motor neurons: Involvement in the pathobiology of ALS mice
-
Martin, L.J.; Gertz, B.; Pan, Y.; Price, A.C.; Molkentin, J.D.; Chang, Q. The mitochondrial permeability transition pore in motor neurons: involvement in the pathobiology of ALS mice. Exp. Neurol. 2009, 218, 333-46.
-
(2009)
Exp. NeuRol
, vol.218
, pp. 333-346
-
-
Martin, L.J.1
Gertz, B.2
Pan, Y.3
Price, A.C.4
Molkentin, J.D.5
Chang, Q.6
-
48
-
-
0031017323
-
Mitochondrial participation in the intracellular Ca2+ network
-
Babcock, D.F.; Herrington, J.; Goodwin, P.C.; Park, Y.B.; Hille, B. Mitochondrial participation in the intracellular Ca2+ network. J. Cell. Biol., 1997, 136, 833-44.
-
(1997)
J. Cell. Biol
, vol.136
, pp. 833-844
-
-
Babcock, D.F.1
Herrington, J.2
Goodwin, P.C.3
Park, Y.B.4
Hille, B.5
-
49
-
-
62149094382
-
Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1 G93A mice
-
Jaiswal, M.K.; Keller, B.U. Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1 G93A mice. Mol. Pharmacol., 2009, 75, 478-89.
-
(2009)
Mol. Pharmacol
, vol.75
, pp. 478-489
-
-
Jaiswal, M.K.1
Keller, B.U.2
-
50
-
-
0036787810
-
Inflammatory processes in amyotrophic lateral sclerosis
-
McGeer, P.L.; McGeer, E.G. Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve, 2002, 26, 459-70.
-
(2002)
Muscle Nerve
, vol.26
, pp. 459-470
-
-
McGeer, P.L.1
McGeer, E.G.2
-
51
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
Boillee, S.; Yamanaka, K.; Lobsiger, C.S.; Copeland, N.G.; Jenkins, N.A.; Kassiotis, G.; Kollias, G.; Cleveland, D.W. Onset and progression in inherited ALS determined by motor neurons and microglia. Science, 2006, 312, 1389-92.
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillee, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
52
-
-
63049130632
-
A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis
-
Mitchell, R.M.; Freeman, W.M.; Randazzo, W.T.; Stephens, H.E.; Beard, J.L.; Simmons, Z.; Connor, J.R. A CSF biomarker panel for identification of patients with amyotrophic lateral sclerosis. Neurology, 2009, 72, 14-9.
-
(2009)
NeuRology
, vol.72
, pp. 14-19
-
-
Mitchell, R.M.1
Freeman, W.M.2
Randazzo, W.T.3
Stephens, H.E.4
Beard, J.L.5
Simmons, Z.6
Connor, J.R.7
-
53
-
-
0035949799
-
Marked increase in cyclooxygenase-2 in ALS spinal cord: Implications for therapy
-
Yasojima, K.; Tourtellotte, W.W.; McGeer, E.G.; McGeer, P.L. Marked increase in cyclooxygenase-2 in ALS spinal cord: implications for therapy. Neurology, 2001, 57, 952-6.
-
(2001)
Neurology
, vol.57
, pp. 952-956
-
-
Yasojima, K.1
Tourtellotte, W.W.2
McGeer, E.G.3
McGeer, P.L.4
-
54
-
-
0034651102
-
Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration
-
Gong, Y.H.; Parsadanian, A.S.; Andreeva, A.; Snider, W.D.; Elliott, J.L. Restricted expression of G86R Cu/Zn superoxide dismutase in astrocytes results in astrocytosis but does not cause motoneuron degeneration. J. Neurosci., 2000, 20, 660-5.
-
(2000)
J. Neurosci
, vol.20
, pp. 660-665
-
-
Gong, Y.H.1
Parsadanian, A.S.2
Andreeva, A.3
Snider, W.D.4
Elliott, J.L.5
-
55
-
-
35548983991
-
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
-
Van Damme, P.; Bogaert, E.; Dewil, M.; Hersmus, N.; Kiraly, D.; Scheveneels, W.; Bockx, I.; Braeken, D.; Verpoorten, N.; Verhoeven, K.; Timmerman, V.; Herijgers, P.; Callewaert, G.; Carmeliet, P.; Van Den Bosch, L.; Robberecht, W. Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity. Proc. Natl. Acad. Sci. U.S.A., 2007, 104, 14825-30.
-
(2007)
Proc. Natl. Acad. Sci. U.S.A
, vol.104
, pp. 14825-14830
-
-
van Damme, P.1
Bogaert, E.2
Dewil, M.3
Hersmus, N.4
Kiraly, D.5
Scheveneels, W.6
Bockx, I.7
Braeken, D.8
Verpoorten, N.9
Verhoeven, K.10
Timmerman, V.11
Herijgers, P.12
Callewaert, G.13
Carmeliet, P.14
Van Den Bosch, L.15
Robberecht, W.16
-
56
-
-
58149379610
-
Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis
-
Vargas, M.R.; Johnson, D.A.; Sirkis, D.W.; Messing, A.; Johnson, J.A. Nrf2 activation in astrocytes protects against neurodegeneration in mouse models of familial amyotrophic lateral sclerosis. J. Neurosci., 2008, 28, 13574-81.
-
(2008)
J. Neurosci
, vol.28
, pp. 13574-13581
-
-
Vargas, M.R.1
Johnson, D.A.2
Sirkis, D.W.3
Messing, A.4
Johnson, J.A.5
-
57
-
-
0034631964
-
Glutamate slows axonal transport of neurofilaments in transfected neurons
-
Ackerley, S.; Grierson, A.J.; Brownlees, J.; Thornhill, P.; Anderton, B.H.; Leigh, P.N.; Shaw, C.E.; Miller, C.C. Glutamate slows axonal transport of neurofilaments in transfected neurons. J. Cell Biol., 2000, 150, 165-76.
-
(2000)
J. Cell Biol
, vol.150
, pp. 165-176
-
-
Ackerley, S.1
Grierson, A.J.2
Brownlees, J.3
Thornhill, P.4
Anderton, B.H.5
Leigh, P.N.6
Shaw, C.E.7
Miller, C.C.8
-
58
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
Puls, I.; Jonnakuty, C.; LaMonte, B.H.; Holzbaur, E.L.; Tokito, M.; Mann, E.; Floeter, M.K.; Bidus, K.; Drayna, D.; Oh, S.J.; Brown, R.H.Jr.; Ludlow, C.L.; Fischbeck, K.H. Mutant dynactin in motor neuron disease. Nat. Genet., 2003, 33, 455-6.
-
(2003)
Nat. Genet
, vol.33
, pp. 455-456
-
-
Puls, I.1
Jonnakuty, C.2
Lamonte, B.H.3
Holzbaur, E.L.4
Tokito, M.5
Mann, E.6
Floeter, M.K.7
Bidus, K.8
Drayna, D.9
Oh, S.J.10
Brown Jr., R.H.11
Ludlow, C.L.12
Fischbeck, K.H.13
-
59
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic tar DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton, M.J.; Igaz, L.M.; Wong, M.M.; Kwong, L.K.; Trojanowski, J.Q.; Lee, V.M. Disturbance of nuclear and cytoplasmic tar DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J. Biol. Chem., 2008, 283, 13302-9.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
60
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi, E.; Valdmanis, P.N.; Dion, P.; Spiegelman, D.; McConkey, B.J.; Vande Velde, C.; Bouchard, J.P.; Lacomblez, L.; Pochigaeva, K.; Salachas, F.; Pradat, P.F.; Camu, W.; Meininger, V.; Dupre, N.; Rouleau, G.A. TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet., 2008, 40, 572-4.
-
(2008)
Nat. Genet
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Vande Velde, C.6
Bouchard, J.P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
61
-
-
33846476127
-
Familial amyotrophic lateral sclerosis: A SOD1-unrelated Japanese family of bulbar type with bunina bodies and ubiquitin-positive skein-like inclusions in lower motor neurons
-
Tagawa, A.; Tan, C.F.; Kikugawa, K.; Fukase, M.; Nakano, R.; Onodera, O.; Nishizawa, M.; Takahashi, H. Familial amyotrophic lateral sclerosis: a SOD1-unrelated Japanese family of bulbar type with bunina bodies and ubiquitin-positive skein-like inclusions in lower motor neurons. Acta Neuropathol., 2007, 113, 205-11.
-
(2007)
Acta Neuropathol
, vol.113
, pp. 205-211
-
-
Tagawa, A.1
Tan, C.F.2
Kikugawa, K.3
Fukase, M.4
Nakano, R.5
Onodera, O.6
Nishizawa, M.7
Takahashi, H.8
-
62
-
-
0029927679
-
Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
-
Shibata, N.; Hirano, A.; Kobayashi, M.; Siddique, T.; Deng, H.X.; Hung, W.Y.; Kato, T.; Asayama, K. Intense superoxide dismutase-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. J. Neuropathol. Exp. Neurol., 1996, 55, 481-90.
-
(1996)
J. Neuropathol. Exp. Neurol
, vol.55
, pp. 481-490
-
-
Shibata, N.1
Hirano, A.2
Kobayashi, M.3
Siddique, T.4
Deng, H.X.5
Hung, W.Y.6
Kato, T.7
Asayama, K.8
-
63
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance, C.; Rogelj, B.; Hortobágyi, T.; De Vos, K.J.; Nishimura, A.L.; Sreedharan, J.; Hu, X.; Smith, B.; Ruddy, D.; Wright, P.; Ganesalingam, J.; Williams, K.L.; Tripathi, V.; Al-Saraj, S.; AlChalabi, A.; Leigh, P.N.; Blair, I.P.; Nicholson, G.; de Belleroche, J.; Gallo, J.M.; Miller, C.C.; Shaw, C.E. Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science, 2009, 323, 1208-11.
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobágyi, T.3
de Vos, K.J.4
Nishimura, A.L.5
Sreedharan, J.6
Hu, X.7
Smith, B.8
Ruddy, D.9
Wright, P.10
Ganesalingam, J.11
Williams, K.L.12
Tripathi, V.13
Al-Saraj, S.14
Alchalabi, A.15
Leigh, P.N.16
Blair, I.P.17
Nicholson, G.18
de Belleroche, J.19
Gallo, J.M.20
Miller, C.C.21
Shaw, C.E.22
more..
-
64
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski, T.J.Jr.; Bosco, D.A.; Leclerc, A.L.; Tamrazian, E.; Vanderburg, C.R.; Russ, C.; Davis, A.; Gilchrist, J.; Kasarskis, E.J.; Munsat, T.; Valdmanis, P.; Rouleau, G.A.; Hosler, B.A.; Cortelli, P.; de Jong, P.J.; Yoshinaga, Y.; Haines, J.L.; Pericak-Vance, M.A.; Yan, J.; Ticozzi, N.; Siddique, T.; McKenna-Yasek, D.; Sapp, P.C.; Horvitz, H.R.; Landers, J.E.; Brown, R.H.Jr. Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science, 2009, 323, 1205-8.
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
Davis, A.7
Gilchrist, J.8
Kasarskis, E.J.9
Munsat, T.10
Valdmanis, P.11
Rouleau, G.A.12
Hosler, B.A.13
Cortelli, P.14
de Jong, P.J.15
Yoshinaga, Y.16
Haines, J.L.17
Pericak-Vance, M.A.18
Yan, J.19
Ticozzi, N.20
Siddique, T.21
McKenna-Yasek, D.22
Sapp, P.C.23
Horvitz, H.R.24
Landers, J.E.25
Brown Jr., R.H.26
more..
-
65
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F.U.; Hayer-Hartl, M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science, 2002, 295, 1852-8.
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
66
-
-
33750975902
-
Failure of protein quality control in amyotrophic lateral sclerosis
-
Kabashi, E.; Durham, H.D. Failure of protein quality control in amyotrophic lateral sclerosis. Biochim. Biophys. Acta, 2006, 1762, 1038-50.
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1038-1050
-
-
Kabashi, E.1
Durham, H.D.2
-
67
-
-
53149114499
-
Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS
-
Kalmar, B.; Novoselov, S.; Gray, A.; Cheetham, M.E.; Margulis, B.; Greensmith, L. Late stage treatment with arimoclomol delays disease progression and prevents protein aggregation in the SOD1 mouse model of ALS. J. Neurochem., 2008, 107, 339-50.
-
(2008)
J. Neurochem
, vol.107
, pp. 339-350
-
-
Kalmar, B.1
Novoselov, S.2
Gray, A.3
Cheetham, M.E.4
Margulis, B.5
Greensmith, L.6
-
69
-
-
84980075070
-
Ueber die einwirkung des phosphorpentachlorids auf senföle und verwandte körper
-
Hofmann, A.W. Ueber die einwirkung des phosphorpentachlorids auf senföle und verwandte körper. Berichte der deutschen chemischen Gesellschaft., 1879, 12, 1126-30.
-
(1879)
Berichte Der Deutschen Chemischen Gesellschaft
, vol.12
, pp. 1126-1130
-
-
Hofmann, A.W.1
-
70
-
-
0345460397
-
Pharmacological properties of benzazoles. I. Relationship between structure and paralyzing action
-
Domino, E.F.; Unna, K.R.; Kerwin, J. Pharmacological properties of benzazoles. I. Relationship between structure and paralyzing action. J. Pharmacol. Exp. Ther. 1952, 105, 486-97.
-
(1952)
J. Pharmacol. Exp. Ther
, vol.105
, pp. 486-497
-
-
Domino, E.F.1
Unna, K.R.2
Kerwin, J.3
-
71
-
-
0022362589
-
2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission: Anticonvulsant properties
-
Mizoule, J.; Meldrum, B.; Mazadier, M.; Croucher, M.; Ollat, C.; Uzan, A.; Legrand, J.J.; Gueremy, C.; Le Fur, G. 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission: anticonvulsant properties. Neuropharmacology, 1985, 24, 767-73.
-
(1985)
NeuroPharmacology
, vol.24
, pp. 767-773
-
-
Mizoule, J.1
Meldrum, B.2
Mazadier, M.3
Croucher, M.4
Ollat, C.5
Uzan, A.6
Legrand, J.J.7
Gueremy, C.8
Le Fur, G.9
-
72
-
-
0022384359
-
2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission: Biochemical properties
-
Benavides, J.; Camelin, J.C.; Mitrani, N.; Flamand, F.; Uzan, A.; Legrand, J.J.; Gueremy, C.; Le Fur, G. 2-amino-6-trifluoromethoxy benzothiazole, a possible antagonist of excitatory amino acid neurotransmission: biochemical properties. Neuropharmacology, 1985, 24, 1085-92.
-
(1985)
Neuropharmacology
, vol.24
, pp. 1085-1092
-
-
Benavides, J.1
Camelin, J.C.2
Mitrani, N.3
Flamand, F.4
Uzan, A.5
Legrand, J.J.6
Gueremy, C.7
Le Fur, G.8
-
73
-
-
34248365309
-
Benzothiazoles: A new profile of biological activities
-
Rana, A.; Siddiqui, N.; Kahn, S.A. Benzothiazoles: a new profile of biological activities. Indian J. Pharm. Sci., 2007, 69, 10-7.
-
(2007)
Indian J. Pharm. Sci
, vol.69
, pp. 10-17
-
-
Rana, A.1
Siddiqui, N.2
Kahn, S.A.3
-
74
-
-
0142227938
-
Efficient conversion of substituted aryl thioureas to 2-aminobenzothiazoles using benzyltrimethylammonium tribromide
-
Jordan, A.D.; Luo, C.; Reitz, A.B. Efficient conversion of substituted aryl thioureas to 2-aminobenzothiazoles using benzyltrimethylammonium tribromide. J. Org. Chem., 2003, 68, 8693-6.
-
(2003)
J. Org. Chem
, vol.68
, pp. 8693-8696
-
-
Jordan, A.D.1
Luo, C.2
Reitz, A.B.3
-
75
-
-
4243914416
-
Diazastyryls with substituents containing fluorine
-
Yagupol'skii, L.M.; Gandel'sman L.Z. Diazastyryls with substituents containing fluorine. Chem. Abs., 1964, 60, 692.
-
(1964)
Chem. Abs
, vol.60
, pp. 692
-
-
Yagupol'skii, L.M.1
Gandel'sman, L.Z.2
-
76
-
-
0028097839
-
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/riluzole study group
-
Bensimon, G.; Lacomblez, L.; Meininger, V. A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/riluzole study group. N. Engl. J. Med., 1994, 330, 585-91.
-
(1994)
N. Engl. J. Med
, vol.330
, pp. 585-591
-
-
Bensimon, G.1
Lacomblez, L.2
Meininger, V.3
-
77
-
-
0034517831
-
What has changed with riluzole?
-
Meininger, V.; Lacomblez, L.; Salachas, F. What has changed with riluzole? J. Neurol., 2000, 247, 19-22.
-
(2000)
J. Neurol
, vol.247
, pp. 19-22
-
-
Meininger, V.1
Lacomblez, L.2
Salachas, F.3
-
78
-
-
0033614947
-
Riluzole series. Synthesis and in vivo antiglutamate activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines
-
Jimonet, P.; Audiau, F.; Barreau, M.; Blanchard, J.C.; Boireau, A.; Bour, Y.; Coleno, M.A.; Doble, A.; Doerflinger, G.; Huu, C.D.; Donat, M.H.; Duchesne, J.M.; Ganil, P.; Guérémy, C.; Honor, E.; Just, B.; Kerphirique, R.; Gontier, S.; Hubert, P.; Laduron, P.M.; Le Blevec, J.; Meunier, M.; Miquet, J.M.; Nemecek, C.; Mignani, S. Riluzole series. Synthesis and in vivo antiglutamate activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines. J. Med. Chem., 1999, 42, 2828-43.
-
(1999)
J. Med. Chem
, vol.42
, pp. 2828-2843
-
-
Jimonet, P.1
Audiau, F.2
Barreau, M.3
Blanchard, J.C.4
Boireau, A.5
Bour, Y.6
Coleno, M.A.7
Doble, A.8
Doerflinger, G.9
Huu, C.D.10
Donat, M.H.11
Duchesne, J.M.12
Ganil, P.13
Guérémy, C.14
Honor, E.15
Just, B.16
Kerphirique, R.17
Gontier, S.18
Hubert, P.19
Laduron, P.M.20
Le Blevec, J.21
Meunier, M.22
Miquet, J.M.23
Nemecek, C.24
Mignani, S.25
more..
-
79
-
-
0027970096
-
Substituted 2-benzothiazolamines as sodium flux inhibitors: Quantitative structure-activity relationships and anticonvulsant activity
-
Hays, S.J.; Rice, M.J.; Ortwine, D.F.; Johnson, G.; Schwarz, R.D.; Boyd, D.K.; Copeland, L.F.; Vartanian, M.G.; Boxer, P.A. Substituted 2-benzothiazolamines as sodium flux inhibitors: quantitative structure-activity relationships and anticonvulsant activity. J. Pharm. Sci., 1994, 83, 1425-32.
-
(1994)
J. Pharm. Sci
, vol.83
, pp. 1425-1432
-
-
Hays, S.J.1
Rice, M.J.2
Ortwine, D.F.3
Johnson, G.4
Schwarz, R.D.5
Boyd, D.K.6
Copeland, L.F.7
Vartanian, M.G.8
Boxer, P.A.9
-
80
-
-
0027439986
-
Riluzole prevents anoxic injury in cultured cerebellar granule neurons
-
Dessi, F.; Ben-Ari, Y.; Charriaut-Marlangue C. Riluzole prevents anoxic injury in cultured cerebellar granule neurons. Eur. J. Pharmacol., 1993, 250, 325-8.
-
(1993)
Eur. J. PharMacol
, vol.250
, pp. 325-328
-
-
Dessi, F.1
Ben-Ari, Y.2
Charriaut-Marlangue, C.3
-
81
-
-
33845288983
-
Delayed riluzole treatment is able to rescue injured rat spinal motoneurons
-
Nogradi, A.; Szabo, A.; Pinter, S.; Vrbova, G. Delayed riluzole treatment is able to rescue injured rat spinal motoneurons. Neuroscience, 2007, 144, 431-8.
-
(2007)
NeuroScience
, vol.144
, pp. 431-438
-
-
Nogradi, A.1
Szabo, A.2
Pinter, S.3
Vrbova, G.4
-
82
-
-
2342498238
-
Co-treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury
-
Bergerot, A.; Shortland, P.J.; Anand, P.; Hunt, S.P.; Carlstedt, T. Co-treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury. Exp. Neurol., 2004, 187, 359-66.
-
(2004)
Exp. Neurol
, vol.187
, pp. 359-366
-
-
Bergerot, A.1
Shortland, P.J.2
Anand, P.3
Hunt, S.P.4
Carlstedt, T.5
-
83
-
-
0035177046
-
The effect of riluzole treatment in rats on the survival of injured adult and grafted embryonic motoneurons
-
Nogradi, A.; Vrbova, G. The effect of riluzole treatment in rats on the survival of injured adult and grafted embryonic motoneurons. Eur. J. Neurosci., 2001, 13, 113-8.
-
(2001)
Eur. J. Neurosci
, vol.13
, pp. 113-118
-
-
Nogradi, A.1
Vrbova, G.2
-
84
-
-
0033762036
-
Neuroprotective effects of riluzole and ketamine during transient spinal cord ischemia in the rabbit
-
Lips, J.; de Haan, P.; Bodewits, P.; Vanicky, I.; Dzoljic, M.; Jacobs, M.J.; Kalkman, C.J. Neuroprotective effects of riluzole and ketamine during transient spinal cord ischemia in the rabbit. Anesthesiology, 2000, 93, 1303-11.
-
(2000)
Anesthesiology
, vol.93
, pp. 1303-1311
-
-
Lips, J.1
de Haan, P.2
Bodewits, P.3
Vanicky, I.4
Dzoljic, M.5
Jacobs, M.J.6
Kalkman, C.J.7
-
85
-
-
0034634744
-
Neuroprotective effect of low dose riluzole in gerbil model of transient global ischemia
-
Bae, H.J.; Lee, Y.S.; Kang, D.W.; Koo, J.S.; Yoon, B.W.; Roh, J.K. Neuroprotective effect of low dose riluzole in gerbil model of transient global ischemia. Neurosci. Lett., 2000, 294, 29-32.
-
(2000)
Neurosci. Lett
, vol.294
, pp. 29-32
-
-
Bae, H.J.1
Lee, Y.S.2
Kang, D.W.3
Koo, J.S.4
Yoon, B.W.5
Roh, J.K.6
-
86
-
-
0034255639
-
Ischemic spinal cord injury induced by aortic cross-clamping: Prevention by riluzole
-
Lang-Lazdunski, L.; Heurteaux, C.; Mignon, A.; Mantz, J.; Widmann, C.; Desmonts, J.; Lazdunski, M. Ischemic spinal cord injury induced by aortic cross-clamping: prevention by riluzole. Eur. J. Cardiothorac. Surg., 2000, 18, 174-81.
-
(2000)
Eur. J. Cardiothorac. Surg
, vol.18
, pp. 174-181
-
-
Lang-Lazdunski, L.1
Heurteaux, C.2
Mignon, A.3
Mantz, J.4
Widmann, C.5
Desmonts, J.6
Lazdunski, M.7
-
87
-
-
0034235577
-
Prevention of ischemic spinal cord injury: Comparative effects of magnesium sulfate and riluzole
-
Lang-Lazdunski, L.; Heurteaux, C.; Dupont, H.; Widmann, C.; Lazdunski, M. Prevention of ischemic spinal cord injury: comparative effects of magnesium sulfate and riluzole. J. Vasc. Surg., 2000, 32, 179-89.
-
(2000)
J. Vasc. Surg
, vol.32
, pp. 179-189
-
-
Lang-Lazdunski, L.1
Heurteaux, C.2
Dupont, H.3
Widmann, C.4
Lazdunski, M.5
-
88
-
-
0033151391
-
Neuroprotective effects of riluzole: An electrophysiological and histological analysis in an in vitro model of ischemia
-
Siniscalchi, A.; Zona, C.; Sancesario, G.; D'Angelo, E.; Zeng, Y.C.; Mercuri, N.B.; Bernardi, G. Neuroprotective effects of riluzole: an electrophysiological and histological analysis in an in vitro model of ischemia. Synapse, 1999, 32, 147-52.
-
(1999)
Synapse
, vol.32
, pp. 147-152
-
-
Siniscalchi, A.1
Zona, C.2
Sancesario, G.3
D'Angelo, E.4
Zeng, Y.C.5
Mercuri, N.B.6
Bernardi, G.7
-
89
-
-
0032951770
-
Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping
-
Lang-Lazdunski, L.; Heurteaux, C.; Vaillant, N.; Widmann, C.; Lazdunski, M. Riluzole prevents ischemic spinal cord injury caused by aortic crossclamping. J. Thorac. Cardiovasc. Surg., 1999, 117, 881-9.
-
(1999)
J. Thorac. Cardiovasc. Surg
, vol.117
, pp. 881-889
-
-
Lang-Lazdunski, L.1
Heurteaux, C.2
Vaillant, N.3
Widmann, C.4
Lazdunski, M.5
-
90
-
-
0032978491
-
Riluzole improves functional recovery after ischemia in the rat retina
-
Ettaiche, M.; Fillacier, K.; Widmann, C.; Heurteaux, C.; Lazdunski, M. Riluzole improves functional recovery after ischemia in the rat retina. Invest. Ophthalmol. Vis. Sci., 1999, 40, 729-36.
-
(1999)
Invest. Ophthalmol. Vis. Sci
, vol.40
, pp. 729-736
-
-
Ettaiche, M.1
Fillacier, K.2
Widmann, C.3
Heurteaux, C.4
Lazdunski, M.5
-
91
-
-
0027469132
-
Effect of riluzole on focal cerebral ischemia in rats
-
Wahl, F.; Allix, M.; Plotkine, M.; Boulu, R.G. Effect of riluzole on focal cerebral ischemia in rats. Eur. J. Pharmacol., 1993, 230, 209-14.
-
(1993)
Eur. J. Pharmacol
, vol.230
, pp. 209-214
-
-
Wahl, F.1
Allix, M.2
Plotkine, M.3
Boulu, R.G.4
-
92
-
-
0026767197
-
Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia
-
Pratt, J.; Rataud, J.; Bardot, F.; Roux, M.; Blanchard, J.C.; Laduron, P.M.; Stutzmann, J.M. Neuroprotective actions of riluzole in rodent models of global and focal cerebral ischaemia. Neurosci. Lett., 1992, 140, 225-30.
-
(1992)
Neurosci. Lett
, vol.140
, pp. 225-230
-
-
Pratt, J.1
Rataud, J.2
Bardot, F.3
Roux, M.4
Blanchard, J.C.5
Laduron, P.M.6
Stutzmann, J.M.7
-
93
-
-
0024307317
-
Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils
-
Malgouris, C.; Bardot, F.; Daniel, M.; Pellis, F.; Rataud, J.; Uzan, A.; Blanchard, J.C.; Laduron, P.M. Riluzole, a novel antiglutamate, prevents memory loss and hippocampal neuronal damage in ischemic gerbils. J. Neurosci., 1989, 9, 3720-7.
-
(1989)
J. Neurosci
, vol.9
, pp. 3720-3727
-
-
Malgouris, C.1
Bardot, F.2
Daniel, M.3
Pellis, F.4
Rataud, J.5
Uzan, A.6
Blanchard, J.C.7
Laduron, P.M.8
-
94
-
-
0037198416
-
Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig
-
Wang, J.; Dib, M.; Lenoir, M.; Vago, P.; Eybalin, M.; Hameg, A.; Pujol, R.; Puel, J.L. Riluzole rescues cochlear sensory cells from acoustic trauma in the guinea-pig. Neuroscience, 2002, 111, 635-48.
-
(2002)
Neuroscience
, vol.111
, pp. 635-648
-
-
Wang, J.1
Dib, M.2
Lenoir, M.3
Vago, P.4
Eybalin, M.5
Hameg, A.6
Pujol, R.7
Puel, J.L.8
-
95
-
-
0031666650
-
Electrophysiology of the neuroprotective agent riluzole on striatal spiny neurons
-
Centonze, D.; Calabresi, P.; Pisani, A.; Marinelli, S.; Marfia, G.A.; Bernardi, G. Electrophysiology of the neuroprotective agent riluzole on striatal spiny neurons. Neuropharmacology, 1998, 37, 1063-70.
-
(1998)
Neuropharmacology
, vol.37
, pp. 1063-1070
-
-
Centonze, D.1
Calabresi, P.2
Pisani, A.3
Marinelli, S.4
Marfia, G.A.5
Bernardi, G.6
-
96
-
-
0026490217
-
Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo
-
Cheramy, A.; Barbeito, L.; Godeheu, G.; Glowinski, J. Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neurosci. Lett. 1992, 147, 209-12.
-
(1992)
Neurosci. Lett
, vol.147
, pp. 209-212
-
-
Cheramy, A.1
Barbeito, L.2
Godeheu, G.3
Glowinski, J.4
-
97
-
-
0031786468
-
Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model
-
Bezard, E.; Stutzmann, J.M.; Imbert, C.; Boraud, T.; Boireau, A.; Gross, C.E. Riluzole delayed appearance of parkinsonian motor abnormalities in a chronic MPTP monkey model. Eur. J. Pharmacol., 1998, 356, 101-4.
-
(1998)
Eur. J. PharmaCol
, vol.356
, pp. 101-104
-
-
Bezard, E.1
Stutzmann, J.M.2
Imbert, C.3
Boraud, T.4
Boireau, A.5
Gross, C.E.6
-
98
-
-
0030271253
-
Neuroprotective effects of riluzole on a model of parkinson's disease in the rat
-
Barneoud, P.; Mazadier, M.; Miquet, J.M.; Parmentier, S.; Dubedat, P.; Doble, A.; Boireau A. Neuroprotective effects of riluzole on a model of parkinson's disease in the rat. Neuroscience, 1996, 74, 971-83.
-
(1996)
Neuroscience
, vol.74
, pp. 971-983
-
-
Barneoud, P.1
Mazadier, M.2
Miquet, J.M.3
Parmentier, S.4
Dubedat, P.5
Doble, A.6
Boireau, A.7
-
99
-
-
34948838383
-
European Huntington's Disease Initiative Study Group. Riluzole in Huntington's disease: A 3-year, randomized controlled study
-
Landwehrmeyer, G.B.; Dubois, B.; de Yébenes, J.G.; Kremer, B.; Gaus, W.; Kraus, P.H.; Przuntek, H.; Dib, M.; Doble, A.; Fischer, W.; Ludolph, A.C.; European Huntington's Disease Initiative Study Group. Riluzole in Huntington's disease: a 3-year, randomized controlled study. Ann. Neurol., 2007, 62, 262-72.
-
(2007)
Ann. Neurol
, vol.62
, pp. 262-272
-
-
Landwehrmeyer, G.B.1
Dubois, B.2
de Yébenes, J.G.3
Kremer, B.4
Gaus, W.5
Kraus, P.H.6
Przuntek, H.7
Dib, M.8
Doble, A.9
Fischer, W.10
Ludolph, A.C.11
-
100
-
-
58849122658
-
For the NSG. Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: The NNIPPS study
-
Bensimon, G.; Ludolph, A.; Agid, Y.; Vidailhet, M.; Payan, C.; Leigh, P.N.; for the NSG. Riluzole treatment, survival and diagnostic criteria in Parkinson plus disorders: the NNIPPS study. Brain, 2009, 132, 156-71.
-
(2009)
Brain
, vol.132
, pp. 156-171
-
-
Bensimon, G.1
Ludolph, A.2
Agid, Y.3
Vidailhet, M.4
Payan, C.5
Leigh, P.N.6
-
101
-
-
0029021812
-
Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures
-
Estevez, A.G.; Stutzmann, J.M.; Barbeito, L. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures. Eur. J. Pharmacol., 1995, 280, 47-53.
-
(1995)
Eur. J. Pharmacol
, vol.280
, pp. 47-53
-
-
Estevez, A.G.1
Stutzmann, J.M.2
Barbeito, L.3
-
102
-
-
0032926745
-
Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons
-
Koh, J.Y.; Kim, D.K.; Hwang, J.Y.; Kim, Y.H.; Seo, J.H. Antioxidative and proapoptotic effects of riluzole on cultured cortical neurons. J. Neurochem., 1999, 72, 716-23.
-
(1999)
J. Neurochem
, vol.72
, pp. 716-723
-
-
Koh, J.Y.1
Kim, D.K.2
Hwang, J.Y.3
Kim, Y.H.4
Seo, J.H.5
-
103
-
-
0028170251
-
Neuroprotective effects of riluzole on n-methyl-d-aspartateor veratridine-induced neurotoxicity in rat hippocampal slices
-
Malgouris, C.; Daniel, M.; Doble, A. Neuroprotective effects of riluzole on n-methyl-d-aspartateor veratridine-induced neurotoxicity in rat hippocampal slices. Neurosci. Lett., 1994, 177, 95-9.
-
(1994)
Neurosci. Lett
, vol.177
, pp. 95-99
-
-
Malgouris, C.1
Daniel, M.2
Doble, A.3
-
104
-
-
0027213025
-
Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in xenopus oocytes
-
Debono, M.W.; Le Guern, J.; Canton, T.; Doble, A.; Pradier, L. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in xenopus oocytes. Eur. J. Pharmacol. 1993, 235, 283-9.
-
(1993)
Eur. J. Pharmacol
, vol.235
, pp. 283-289
-
-
Debono, M.W.1
Le Guern, J.2
Canton, T.3
Doble, A.4
Pradier, L.5
-
105
-
-
44649173763
-
Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro
-
Lamanauskas, N.; Nistri, A. Riluzole blocks persistent Na+ and Ca2+ currents and modulates release of glutamate via presynaptic NMDA receptors on neonatal rat hypoglossal motoneurons in vitro. Eur. J. Neurosci., 2008, 27, 2501-14.
-
(2008)
Eur. J. Neurosci
, vol.27
, pp. 2501-2514
-
-
Lamanauskas, N.1
Nistri, A.2
-
106
-
-
0033713305
-
Selective depression of low-release probability excitatory synapses by sodium channel blockers
-
Prakriya, M.; Mennerick, S. Selective depression of low-release probability excitatory synapses by sodium channel blockers. Neuron, 2000, 26, 671-82.
-
(2000)
NeuRon
, vol.26
, pp. 671-682
-
-
Prakriya, M.1
Mennerick, S.2
-
107
-
-
0031036733
-
Effects of riluzole on rat cortical neurones: An in vitro electrophysiological study
-
Siniscalchi, A.; Bonci, A.; Mercuri, N.B.; Bernardi, G. Effects of riluzole on rat cortical neurones: an in vitro electrophysiological study. Br. J. Pharmacol., 1997, 120, 225-30.
-
(1997)
Br. J. Pharmacol
, vol.120
, pp. 225-230
-
-
Siniscalchi, A.1
Bonci, A.2
Mercuri, N.B.3
Bernardi, G.4
-
108
-
-
4744371975
-
Modulation of AMPA receptors in spinal motor neurons by the neuroprotective agent riluzole
-
Albo, F.; Pieri, M.; Zona, C. Modulation of AMPA receptors in spinal motor neurons by the neuroprotective agent riluzole. J. Neurosci. Res., 2004, 78, 200-7.
-
(2004)
J. NeuRosci. Res
, vol.78
, pp. 200-207
-
-
Albo, F.1
Pieri, M.2
Zona, C.3
-
109
-
-
37349063346
-
Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1
-
Fumagalli, E.; Funicello, M.; Rauen, T.; Gobbi, M.; Mennini, T. Riluzole enhances the activity of glutamate transporters GLAST, GLT1 and EAAC1. Eur. J. Pharmacol., 2008, 578, 171-6.
-
(2008)
Eur. J. Pharmacol
, vol.578
, pp. 171-176
-
-
Fumagalli, E.1
Funicello, M.2
Rauen, T.3
Gobbi, M.4
Mennini, T.5
-
110
-
-
0027762836
-
The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
-
Martin, D.; Thompson, M.A.; Nadler, J.V. The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur. J. Pharmacol., 1993, 250, 473-6.
-
(1993)
Eur. J. Pharmacol
, vol.250
, pp. 473-476
-
-
Martin, D.1
Thompson, M.A.2
Nadler, J.V.3
-
111
-
-
0033913617
-
Effects of riluzole on electrically evoked neurotransmitter release
-
Jehle, T.; Bauer, J.; Blauth, E.; Hummel, A.; Darstein, M.; Freiman, T.M.; Feuerstein, T.J. Effects of riluzole on electrically evoked neurotransmitter release. Br. J. Pharmacol., 2000, 130, 1227-34.
-
(2000)
Br. J. Pharmacol
, vol.130
, pp. 1227-1234
-
-
Jehle, T.1
Bauer, J.2
Blauth, E.3
Hummel, A.4
Darstein, M.5
Freiman, T.M.6
Feuerstein, T.J.7
-
112
-
-
0030944883
-
Mechanism of calcium entry during axon injury and degeneration
-
LoPachin, R.M.; Lehning, E.J. Mechanism of calcium entry during axon injury and degeneration. Toxicol. Appl. Pharmacol., 1997, 143, 233-44.
-
(1997)
Toxicol. Appl. Pharmacol
, vol.143
, pp. 233-244
-
-
Lopachin, R.M.1
Lehning, E.J.2
-
113
-
-
33644814322
-
Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyper-oxia-induced abnormal vessel formation in vivo
-
Yoo, M.H.; Hyun, H.J.; Koh, J.Y.; Yoon, Y.H. Riluzole inhibits VEGF-induced endothelial cell proliferation in vitro and hyper-oxia-induced abnormal vessel formation in vivo. Invest. Ophthalmol. Vis. Sci., 2005, 46, 4780-7.
-
(2005)
Invest. OphthalMol. Vis. Sci.
, vol.46
, pp. 4780-4787
-
-
Yoo, M.H.1
Hyun, H.J.2
Koh, J.Y.3
Yoon, Y.H.4
-
114
-
-
62949103631
-
Riluzole protects against glutamate-induced slowing of neurofilament axonal transport
-
Stevenson, A.; Yates, D.M.; Manser, C.; De Vos, K.J.; Vagnoni, A.; Leigh, P.N.; McLoughlin, D.M.; Miller, C.C. Riluzole protects against glutamate-induced slowing of neurofilament axonal transport. Neurosci. Lett., 2009, 454, 161-4.
-
(2009)
Neurosci. Lett
, vol.454
, pp. 161-164
-
-
Stevenson, A.1
Yates, D.M.2
Manser, C.3
de Vos, K.J.4
Vagnoni, A.5
Leigh, P.N.6
McLoughlin, D.M.7
Miller, C.C.8
-
115
-
-
1642462299
-
Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes)
-
Wang, S.J.; Wang, K.Y.; Wang, W.C. Mechanisms underlying the riluzole inhibition of glutamate release from rat cerebral cortex nerve terminals (synaptosomes). Neuroscience, 2004, 125, 191-201.
-
(2004)
Neuroscience
, vol.125
, pp. 191-201
-
-
Wang, S.J.1
Wang, K.Y.2
Wang, W.C.3
-
116
-
-
0025299982
-
Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia
-
Stys, P.K.; Ransom, B.R.; Waxman, S.G. Effects of polyvalent cations and dihydropyridine calcium channel blockers on recovery of CNS white matter from anoxia. Neurosci. Lett., 1990, 115, 293-299.
-
(1990)
Neurosci. Lett
, vol.115
, pp. 293-299
-
-
Stys, P.K.1
Ransom, B.R.2
Waxman, S.G.3
-
117
-
-
0025925116
-
Na+-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian central nervous system white matter
-
Stys, P.K.; Waxman, S.G.; Ransom, BR. Na+-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian central nervous system white matter. Ann. Neurol., 1991, 30, 375-80.
-
(1991)
Ann. Neurol
, vol.30
, pp. 375-380
-
-
Stys, P.K.1
Waxman, S.G.2
Ransom, B.R.3
-
118
-
-
0028355070
-
Anoxic injury of rat optic nerve: Ultrastructural evidence for coupling between Na+ influx and Ca2+-mediated injury in myelinated CNS axons
-
Waxman, S.G.; Black, J.A.; Ransom, B.R.; Stys, P.K. Anoxic injury of rat optic nerve: ultrastructural evidence for coupling between Na+ influx and Ca2+-mediated injury in myelinated CNS axons. Brain. Res., 1994, 644, 197-204.
-
(1994)
Brain. Res
, vol.644
, pp. 197-204
-
-
Waxman, S.G.1
Black, J.A.2
Ransom, B.R.3
Stys, P.K.4
-
119
-
-
0028365121
-
Block of the rat brain IIa sodium channel alpha subunit by the neuroprotective drug riluzole
-
Hebert, T.; Drapeau, P.; Pradier, L.; Dunn, R.J. Block of the rat brain IIa sodium channel alpha subunit by the neuroprotective drug riluzole. Mol. Pharmacol., 1994, 45, 1055-60.
-
(1994)
Mol. Pharmacol
, vol.45
, pp. 1055-1060
-
-
Hebert, T.1
Drapeau, P.2
Pradier, L.3
Dunn, R.J.4
-
120
-
-
0842284657
-
Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons
-
Kononenko, N.I.; Shao, L.R.; Dudek, F.E. Riluzole-sensitive slowly inactivating sodium current in rat suprachiasmatic nucleus neurons. J. Neurophysiol., 2004, 91, 710-8.
-
(2004)
J. Neurophysiol
, vol.91
, pp. 710-718
-
-
Kononenko, N.I.1
Shao, L.R.2
Dudek, F.E.3
-
121
-
-
0033787252
-
Riluzole inhibits the persistent sodium current in mammalian CNS neurons
-
Urbani, A, Belluzzi, O. Riluzole inhibits the persistent sodium current in mammalian CNS neurons. Eur. J. Neurosci., 2000, 12, 3567-74.
-
(2000)
Eur. J. Neurosci
, vol.12
, pp. 3567-3574
-
-
Urbani, A.1
Belluzzi, O.2
-
122
-
-
0025263891
-
Molecular mechanisms of local anesthesia: A review
-
Butterworth, J.F. 4th, Strichartz, G.R. Molecular mechanisms of local anesthesia: a review. Anesthesiology, 1990, 72, 711-34.
-
(1990)
Anesthesiology
, vol.72
, pp. 711-734
-
-
Butterworth 4th., J.F.1
Strichartz, G.R.2
-
123
-
-
0026334826
-
Riluzole specifically blocks inactivated na channels in myelinated nerve fibre
-
Benoit, E.; Escande, D. Riluzole specifically blocks inactivated na channels in myelinated nerve fibre. Pflügers Arch., 1991, 419, 603-609.
-
(1991)
Pflügers Arch
, vol.419
, pp. 603-609
-
-
Benoit, E.1
Escande, D.2
-
124
-
-
0034036946
-
Frequency-independent blockade of cardiac Na+ channels by riluzole: Comparison with established anticonvulsants and class I anti-arrhythmics
-
Mestre, M.; Djellas, Y.; Carriot, T.; Cavero, I. Frequency-independent blockade of cardiac Na+ channels by riluzole: comparison with established anticonvulsants and class I anti-arrhythmics. Fundam. Clin. Pharmacol., 2000, 14, 107-17.
-
(2000)
Fundam. Clin. Pharmacol
, vol.14
, pp. 107-117
-
-
Mestre, M.1
Djellas, Y.2
Carriot, T.3
Cavero, I.4
-
125
-
-
37049035622
-
Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells
-
Wang, Y.J.; Lin, M.W.; Lin, A.A.; Wu, S.N. Riluzole-induced block of voltage-gated Na+ current and activation of BKCa channels in cultured differentiated human skeletal muscle cells. Life. Sci., 2008, 82, 11-20.
-
(2008)
Life. Sci
, vol.82
, pp. 11-20
-
-
Wang, Y.J.1
Lin, M.W.2
Lin, A.A.3
Wu, S.N.4
-
126
-
-
85030304750
-
Amyotrophic lateral sclerosis, excitotoxicity and riluzole
-
Obrenovitch, T.P. Amyotrophic lateral sclerosis, excitotoxicity and riluzole. Trends. Pharmacol. Sci., 1998, 19, 9-11.
-
(1998)
Trends. Pharmacol. Sci
, vol.19
, pp. 9-11
-
-
Obrenovitch, T.P.1
-
127
-
-
0028491754
-
Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative
-
Jimonet, P.; Barreau, M.; Blanchard, J.C.; Boireau, A.; Doble, A.; Laduron, P.; Lavayre, J.; Malgouris, C.; Piot, O.; Pratt, J.; Rataud, J.; Reibaud, M.; Mignani, S.; Stutzmann, J.M. Synthesis, anticonvulsant and neuroprotective activities of RP 66055, a riluzole derivative. Bioorg. Med. Chem. 1994, 2, 793-8.
-
(1994)
Bioorg. Med. Chem
, vol.2
, pp. 793-798
-
-
Jimonet, P.1
Barreau, M.2
Blanchard, J.C.3
Boireau, A.4
Doble, A.5
Laduron, P.6
Lavayre, J.7
Malgouris, C.8
Piot, O.9
Pratt, J.10
Rataud, J.11
Reibaud, M.12
Mignani, S.13
Stutzmann, J.M.14
-
128
-
-
0036166936
-
Neuroprotective agent riluzole potentiates postsynaptic GABAA receptor function
-
He, Y.; Benz, A.; Fu, T.; Wang, M.; Covey, D.F.; Zorumski, C.F.; Mennerick, S. Neuroprotective agent riluzole potentiates postsynaptic GABAA receptor function. Neuropharmacology, 2002, 42, 199-209.
-
(2002)
Neuropharmacology
, vol.42
, pp. 199-209
-
-
He, Y.1
Benz, A.2
Fu, T.3
Wang, M.4
Covey, D.F.5
Zorumski, C.F.6
Mennerick, S.7
-
129
-
-
0028365658
-
Riluzole, a novel antiglutamate, blocks gaba uptake by striatal synaptosomes
-
Mantz, J.; Laudenbach, V.; Lecharny, J.B.; Henzel, D.; Desmonts, J.M. Riluzole, a novel antiglutamate, blocks gaba uptake by striatal synaptosomes. Eur. J. Pharmacol., 1994, 257, R7-8.
-
(1994)
Eur. J. Pharmacol
, vol.257
, pp. 7-8
-
-
Mantz, J.1
Laudenbach, V.2
Lecharny, J.B.3
Henzel, D.4
Desmonts, J.M.5
-
130
-
-
0023951749
-
Riluzole, a glutamate antagonist, enhances slow wave and REM sleep in rats
-
Stutzmann, J.M.; Lucas, M.; Blanchard, J.C.; Laduron, P.M. Riluzole, a glutamate antagonist, enhances slow wave and REM sleep in rats. Neurosci. Lett., 1988, 88, 195-200.
-
(1988)
Neurosci. Lett
, vol.88
, pp. 195-200
-
-
Stutzmann, J.M.1
Lucas, M.2
Blanchard, J.C.3
Laduron, P.M.4
-
131
-
-
0035074328
-
Effects of riluzole on cortical excitability in patients with amyotrophic lateral sclerosis
-
Stefan, K.; Kunesch, E.; Benecke, R.; Classen, J. Effects of riluzole on cortical excitability in patients with amyotrophic lateral sclerosis. Ann. Neurol., 2001, 49, 536-9.
-
(2001)
Ann. Neurol
, vol.49
, pp. 536-539
-
-
Stefan, K.1
Kunesch, E.2
Benecke, R.3
Classen, J.4
-
132
-
-
0033830726
-
A novel neuroprotective mechanism of riluzole: Direct inhibition of protein kinase c
-
Noh, K.M.; Hwang, J.Y.; Shin, H.C.; Koh, J.Y. A novel neuroprotective mechanism of riluzole: direct inhibition of protein kinase c. Neurobiol. Dis., 2000, 7, 375-83.
-
(2000)
Neurobiol. Dis
, vol.7
, pp. 375-383
-
-
Noh, K.M.1
Hwang, J.Y.2
Shin, H.C.3
Koh, J.Y.4
-
133
-
-
0026663768
-
Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on d-(3h)aspartate release from cultured cerebellar granule cells
-
Doble, A.; Hubert, J.P.; Blanchard, J.C. Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on d-(3h)aspartate release from cultured cerebellar granule cells. Neurosci. Lett., 1992, 140, 251-4.
-
(1992)
NeuroSci. Lett
, vol.140
, pp. 251-254
-
-
Doble, A.1
Hubert, J.P.2
Blanchard, J.C.3
-
134
-
-
0034698248
-
Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes
-
Azbill, R.D.; Mu, X.; Springer, J.E. Riluzole increases high-affinity glutamate uptake in rat spinal cord synaptosomes. Brain. Res., 2000, 871, 175-80.
-
(2000)
Brain. Res
, vol.871
, pp. 175-180
-
-
Azbill, R.D.1
Mu, X.2
Springer, J.E.3
-
135
-
-
0031421232
-
Population pharmacokinetics of riluzole in patients with amyotrophic lateral sclerosis
-
Bruno, R.; Vivier, N.; Montay, G.; Le Liboux, A.; Powe, L.K.; Delumeau, J.C.; Rhodes, G.R. Population pharmacokinetics of riluzole in patients with amyotrophic lateral sclerosis. Clin. Pharmacol. Ther., 1997, 62, 518-26.
-
(1997)
Clin. PharmaCol. Ther
, vol.62
, pp. 518-526
-
-
Bruno, R.1
Vivier, N.2
Montay, G.3
Le Liboux, A.4
Powe, L.K.5
Delumeau, J.C.6
Rhodes, G.R.7
-
136
-
-
0032781889
-
A comparison of the pharmacokinetics and tolerability of riluzole after repeat dose administration in healthy elderly and young volunteers
-
Le Liboux, A.; Cachia, J.P.; Kirkesseli, S.; Gautier, J.Y.; Guimart, C.; Montay, G.; Peeters, P.A.; Groen, E.; Jonkman, J.H.; Wemer, J. A comparison of the pharmacokinetics and tolerability of riluzole after repeat dose administration in healthy elderly and young volunteers. J. Clin. Pharmacol., 1999, 39, 480-6.
-
(1999)
J. Clin. Pharmacol
, vol.39
, pp. 480-486
-
-
Le Liboux, A.1
Cachia, J.P.2
Kirkesseli, S.3
Gautier, J.Y.4
Guimart, C.5
Montay, G.6
Peeters, P.A.7
Groen, E.8
Jonkman, J.H.9
Wemer, J.10
-
137
-
-
0030924553
-
Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro
-
Sanderink, G.J.; Bournique, B.; Stevens, J.; Petry, M.; Martinet, M. Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro. J. Pharmacol. Exp. Ther., 1997, 282, 1465-72.
-
(1997)
J. Pharmacol. Exp. Ther
, vol.282
, pp. 1465-1472
-
-
Sanderink, G.J.1
Bournique, B.2
Stevens, J.3
Petry, M.4
Martinet, M.5
-
138
-
-
42349092390
-
An association study of riluzole serum concentration and survival and disease progression in patients with ALS
-
Groeneveld, G.J.; van Kan, H.J.; Lie-A-Huen, L.; Guchelaar, H.J.; van den Berg, L.H. An association study of riluzole serum concentration and survival and disease progression in patients with ALS. Clin. Pharmacol. Ther., 2008, 83, 718-22.
-
(2008)
Clin. Pharmacol. Ther
, vol.83
, pp. 718-722
-
-
Groeneveld, G.J.1
van Kan, H.J.2
Lie-A-Huen, L.3
Guchelaar, H.J.4
van den Berg, L.H.5
-
139
-
-
0033678985
-
Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation
-
Schwenkreis, P.; Liepert, J.; Witscher, K.; Fischer, W.; Weiller, C.; Malin, J.P.; Tegenthoff, M. Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation. Exp. Brain Res., 2000, 135, 293-9.
-
(2000)
Exp. Brain Res
, vol.135
, pp. 293-299
-
-
Schwenkreis, P.1
Liepert, J.2
Witscher, K.3
Fischer, W.4
Weiller, C.5
Malin, J.P.6
Tegenthoff, M.7
-
140
-
-
8844281519
-
The tolerability of riluzole in the treatment of patients with amyotrophic lateral sclerosis
-
Bensimon, G.; Doble, A. The tolerability of riluzole in the treatment of patients with amyotrophic lateral sclerosis. Expert. Opin. Drug Saf., 2004, 3, 525-34.
-
(2004)
Expert. Opin. Drug Saf
, vol.3
, pp. 525-534
-
-
Bensimon, G.1
Doble, A.2
-
141
-
-
0035886647
-
Inter and intraindividual variability of riluzole serum concentrations in patients with ALS
-
Groeneveld, G.J.; van Kan, H.J.; Torano, J.S.; Veldink, J.H.; Guchelaar, H.J.; Wokke, J.H.; van den Berg, L.H. Inter-and intraindividual variability of riluzole serum concentrations in patients with ALS. J. Neurol. Sci., 2001, 191, 121-5.
-
(2001)
J. Neurol. Sci
, vol.191
, pp. 121-125
-
-
Groeneveld, G.J.1
van Kan, H.J.2
Torano, J.S.3
Veldink, J.H.4
Guchelaar, H.J.5
Wokke, J.H.6
van den Berg, L.H.7
-
142
-
-
0030882699
-
Single-and multiple-dose pharma-cokinetics of riluzole in white subjects
-
Le Liboux, A.; Lefebvre, P.; Le Roux, Y.; Truffinet, P.; Aubeneau, M.; Kirkesseli, S.; Montay, G. Single-and multiple-dose pharma-cokinetics of riluzole in white subjects. J. Clin. Pharmacol., 1997, 37, 820-7.
-
(1997)
J. Clin. Pharmacol
, vol.37
, pp. 820-827
-
-
Le Liboux, A.1
Lefebvre, P.2
Le Roux, Y.3
Truffinet, P.4
Aubeneau, M.5
Kirkesseli, S.6
Montay, G.7
-
143
-
-
1842479298
-
Liquid chromatographic assay for riluzole in mouse plasma and central nervous system tissues
-
Colovic, M.; Zennaro, E.; Caccia, S. Liquid chromatographic assay for riluzole in mouse plasma and central nervous system tissues. J. Chromatogr. B Analyt. Technol. Biomed. Life. Sci., 2004, 803, 305-309.
-
(2004)
J. Chromatogr. B Analyt. Technol. Biomed. Life. Sci
, vol.803
, pp. 305-309
-
-
Colovic, M.1
Zennaro, E.2
Caccia, S.3
-
144
-
-
0029977337
-
Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole study group II
-
Lacomblez, L.; Bensimon, G.; Leigh, P.N.; Guillet, P.; Meininger, V. Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole study group II. Lancet, 1996, 347, 1425-31.
-
(1996)
Lancet
, vol.347
, pp. 1425-1431
-
-
Lacomblez, L.1
Bensimon, G.2
Leigh, P.N.3
Guillet, P.4
Meininger, V.5
-
145
-
-
0031944832
-
An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole
-
Riviere, M.; Meininger, V.; Zeisser, P.; Munsat, T. An analysis of extended survival in patients with amyotrophic lateral sclerosis treated with riluzole. Arch. Neurol., 1998, 55, 526-8.
-
(1998)
Arch. Neurol
, vol.55
, pp. 526-528
-
-
Riviere, M.1
Meininger, V.2
Zeisser, P.3
Munsat, T.4
-
146
-
-
0036257090
-
A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis
-
Bensimon, G.; Lacomblez, L.; Delumeau, J.C.; Bejuit, R.; Truffinet, P.; Meininger, V. A study of riluzole in the treatment of advanced stage or elderly patients with amyotrophic lateral sclerosis. J. Neurol., 2002, 249, 609-15.
-
(2002)
J. Neurol
, vol.249
, pp. 609-615
-
-
Bensimon, G.1
Lacomblez, L.2
Delumeau, J.C.3
Bejuit, R.4
Truffinet, P.5
Meininger, V.6
-
147
-
-
34250208597
-
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND)
-
Miller, R.G.; Mitchell, J.D.; Lyon, M.; Moore, D.H. Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND). Cochrane Database Syst. Rev., 2007, 1, CD001447.
-
(2007)
Cochrane Database Syst. Rev
, Issue.1
, pp. 1447
-
-
Miller, R.G.1
Mitchell, J.D.2
Lyon, M.3
Moore, D.H.4
-
148
-
-
0032995109
-
Acute hepatitis after riluzole administration
-
Remy, A.J.; Camu, W.; Ramos, J.; Blanc, P.; Larrey, D. Acute hepatitis after riluzole administration. J. Hepatol., 1999, 30, 527-30.
-
(1999)
J. Hepatol
, vol.30
, pp. 527-530
-
-
Remy, A.J.1
Camu, W.2
Ramos, J.3
Blanc, P.4
Larrey, D.5
-
149
-
-
0032574290
-
Icteric toxic hepatitis associated with riluzole
-
Castells, L.I.; Gamez, J.; Cervera, C.; Guardia, J. Icteric toxic hepatitis associated with riluzole. Lancet, 1998, 351, 648.
-
(1998)
Lancet
, vol.351
, pp. 648
-
-
Castells, L.I.1
Gamez, J.2
Cervera, C.3
Guardia, J.4
-
151
-
-
70449718115
-
Efficacy of thalidomide for the treatment of amyotrophic lateral sclerosis: A phase II open label clinical trial
-
Stommel, E.W.; Cohen, J.A.; Fadul, C.E.; Cogbill, C.H.; Graber, D.J.; Kingman, L.; Mackenzie, T.; Channon Smith, J.Y.; Harris, B.T. Efficacy of thalidomide for the treatment of amyotrophic lateral sclerosis: a phase II open label clinical trial. Amyotroph. Lateral Scler., 2009, 10, 393-404.
-
(2009)
Amyotroph. LatEral Scler
, vol.10
, pp. 393-404
-
-
Stommel, E.W.1
Cohen, J.A.2
Fadul, C.E.3
Cogbill, C.H.4
Graber, D.J.5
Kingman, L.6
Mackenzie, T.7
Channon Smith, J.Y.8
Harris, B.T.9
-
152
-
-
67049096146
-
Can we eliminate placebo in ALS clinical trials?
-
Simmons, Z. Can we eliminate placebo in ALS clinical trials? Muscle Nerve, 2009, 39, 861-5.
-
(2009)
Muscle Nerve
, vol.39
, pp. 861-865
-
-
Simmons, Z.1
-
153
-
-
70450158934
-
The natural history of ALS is changing: Improved survival
-
Qureshi, M.; Schoenfeld, D.A.; Paliwal, Y.; Shui, A.; Cudkowicz, M.E. The natural history of ALS is changing: improved survival. Amyotroph. Lateral Scler., 2009, 10, 324-31.
-
(2009)
Amyotroph. Lateral Scler
, vol.10
, pp. 324-331
-
-
Qureshi, M.1
Schoenfeld, D.A.2
Paliwal, Y.3
Shui, A.4
Cudkowicz, M.E.5
-
154
-
-
70249116820
-
QALS Study Group. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III
-
Kaufmann, P.; Thompson, J.L.; Levy, G.; Buchsbaum, R.; Shefner, J.; Krivickas, L.S.; Katz, J.; Rollins, Y.; Barohn, R.J.; Jackson, C.E.; Tiryaki, E.; Lomen-Hoerth, C.; Armon, C.; Tandan, R.; Rudnicki, S.A.; Rezania, K.; Sufit, R.; Pestronk, A.; Novella, S.P.; Heiman-Patterson, T.; Kasarskis, E.J.; Pioro, E.P.; Montes, J.; Arbing, R.; Vecchio, D.; Barsdorf, A.; Mitsumoto, H.; Levin, B.; QALS Study Group. Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase III. Ann. Neurol., 2009, 66, 235-44.
-
(2009)
Ann. Neurol
, vol.66
, pp. 235-244
-
-
Kaufmann, P.1
Thompson, J.L.2
Levy, G.3
Buchsbaum, R.4
Shefner, J.5
Krivickas, L.S.6
Katz, J.7
Rollins, Y.8
Barohn, R.J.9
Jackson, C.E.10
Tiryaki, E.11
Lomen-Hoerth, C.12
Armon, C.13
Tandan, R.14
Rudnicki, S.A.15
Rezania, K.16
Sufit, R.17
Pestronk, A.18
Novella, S.P.19
Heiman-Patterson, T.20
Kasarskis, E.J.21
Pioro, E.P.22
Montes, J.23
Arbing, R.24
Vecchio, D.25
Barsdorf, A.26
Mitsumoto, H.27
Levin, B.28
more..
-
155
-
-
48349092132
-
Combination Drug Selection Trial Study Group. A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS
-
Gordon, P.H.; Cheung, Y.K.; Levin, B.; Andrews, H.; Doorish, C.; Macarthur, R.B.; Montes, J.; Bednarz, K.; Florence, J.; Rowin, J.; Boylan, K.; Mozaffar, T.; Tandan, R.; Mitsumoto, H.; Kelvin, E.A.; Chapin, J.; Bedlack, R.; Rivner, M.; McCluskey, L.F.; Pestronk, A.; Graves, M.; Sorenson, E.J.; Barohn, R.J.; Belsh, J.M.; Lou, J.S.; Levine, T.; Saperstein, D.; Miller, R.G.; Scelsa, S.N.; Combination Drug Selection Trial Study Group. A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph. Lateral Scler., 2008, 9, 212-22.
-
(2008)
Amyotroph. Lateral Scler
, vol.9
, pp. 212-222
-
-
Gordon, P.H.1
Cheung, Y.K.2
Levin, B.3
Andrews, H.4
Doorish, C.5
Macarthur, R.B.6
Montes, J.7
Bednarz, K.8
Florence, J.9
Rowin, J.10
Boylan, K.11
Mozaffar, T.12
Tandan, R.13
Mitsumoto, H.14
Kelvin, E.A.15
Chapin, J.16
Bedlack, R.17
Rivner, M.18
McCluskey, L.F.19
Pestronk, A.20
Graves, M.21
Sorenson, E.J.22
Barohn, R.J.23
Belsh, J.M.24
Lou, J.S.25
Levine, T.26
Saperstein, D.27
Miller, R.G.28
Scelsa, S.N.29
more..
-
156
-
-
33645802414
-
Pentoxifylline in ALS: A doubleblind, randomized, multicenter, placebo-controlled trial
-
Meininger, V.; Asselain, B.; Guillet, P.; Leigh, P.N.; Ludolph, A.; Lacomblez, L.; Robberecht, W. Pentoxifylline in ALS: a doubleblind, randomized, multicenter, placebo-controlled trial. Neurology, 2006, 66, 88-92.
-
(2006)
Neurology
, vol.66
, pp. 88-92
-
-
Meininger, V.1
Asselain, B.2
Guillet, P.3
Leigh, P.N.4
Ludolph, A.5
Lacomblez, L.6
Robberecht, W.7
-
157
-
-
36148960127
-
Western ALS Study Group. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: A phase III randomised trial
-
Gordon, P.H.; Moore, D.H.; Miller, R.G.; Florence, J.M.; Verheijde, J.L.; Doorish, C.; Hilton, J.F.; Spitalny, G.M.; MacArthur, R.B.; Mitsumoto, H.; Neville, H.E.; Boylan, K.; Mozaffar, T.; Belsh, J.M.; Ravits, J.; Bedlack, R.S.; Graves, M.C.; McCluskey, L.F.; Barohn, R.J.; Tandan, R.; Western ALS Study Group. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol., 2007, 6, 1045-53.
-
(2007)
Lancet Neurol
, vol.6
, pp. 1045-1053
-
-
Gordon, P.H.1
Moore, D.H.2
Miller, R.G.3
Florence, J.M.4
Verheijde, J.L.5
Doorish, C.6
Hilton, J.F.7
Spitalny, G.M.8
Macarthur, R.B.9
Mitsumoto, H.10
Neville, H.E.11
Boylan, K.12
Mozaffar, T.13
Belsh, J.M.14
Ravits, J.15
Bedlack, R.S.16
Graves, M.C.17
McCluskey, L.F.18
Barohn, R.J.19
Tandan, R.20
more..
-
158
-
-
10744222650
-
Northeast ALS Consortium. A randomized, placebocontrolled trial of topiramate in amyotrophic lateral sclerosis
-
Cudkowicz, M.E.; Shefner, J.M.; Schoenfeld, D.A.; Brown, R.H. Jr.; Johnson, H.; Qureshi, M.; Jacobs, M.; Rothstein, J.D.; Appel, S.H.; Pascuzzi, R.M.; Heiman-Patterson, T.D.; Donofrio, P.D.; David, W.S.; Russell, J.A.; Tandan, R.; Pioro, E.P.; Felice, K.J.; Rosenfeld, J.; Mandler, R.N.; Sachs, G.M.; Bradley, W.G.; Raynor, E.M.; Baquis, G.D.; Belsh, J.M.; Novella, S.; Goldstein, J.; Hulihan, J.; Northeast ALS Consortium. A randomized, placebocontrolled trial of topiramate in amyotrophic lateral sclerosis. Neurology, 2003, 61, 456-64.
-
(2003)
NeuRology
, vol.61
, pp. 456-464
-
-
Cudkowicz, M.E.1
Shefner, J.M.2
Schoenfeld, D.A.3
Brown Jr., R.H.4
Johnson, H.5
Qureshi, M.6
Jacobs, M.7
Rothstein, J.D.8
Appel, S.H.9
Pascuzzi, R.M.10
Heiman-Patterson, T.D.11
Donofrio, P.D.12
David, W.S.13
Russell, J.A.14
Tandan, R.15
Pioro, E.P.16
Felice, K.J.17
Rosenfeld, J.18
Mandler, R.N.19
Sachs, G.M.20
Bradley, W.G.21
Raynor, E.M.22
Baquis, G.D.23
Belsh, J.M.24
Novella, S.25
Goldstein, J.26
Hulihan, J.27
more..
-
159
-
-
58249136197
-
Unapproved drug use: Compassionate or cause for concern?
-
Ross, E. Unapproved drug use: compassionate or cause for concern? Lancet Neurol., 2009, 8, 136-7.
-
(2009)
Lancet Neurol
, vol.8
, pp. 136-137
-
-
Ross, E.1
-
160
-
-
33947323759
-
Lost in translation: Treatment trials in the SOD1 mouse and in human ALS
-
Benatar, M. Lost in translation: treatment trials in the SOD1 mouse and in human ALS. Neurobiol. Dis., 2007, 26, 1-13.
-
(2007)
Neurobiol. Dis
, vol.26
, pp. 1-13
-
-
Benatar, M.1
-
161
-
-
0037381851
-
Efficient three-drug cocktail for disease induced by mutant superoxide dismutase
-
Kriz, J.; Gowing, G.; Julien, J.P. Efficient three-drug cocktail for disease induced by mutant superoxide dismutase. Ann. Neurol., 2003, 53, 429-36.
-
(2003)
Ann. Neurol
, vol.53
, pp. 429-436
-
-
Kriz, J.1
Gowing, G.2
Julien, J.P.3
-
162
-
-
0037310563
-
Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS
-
Zhang, W.; Narayanan, M.; Friedlander, R.M. Additive neuroprotective effects of minocycline with creatine in a mouse model of ALS. Ann. Neurol., 2003, 53, 267-70.
-
(2003)
Ann. Neurol
, vol.53
, pp. 267-270
-
-
Zhang, W.1
Narayanan, M.2
Friedlander, R.M.3
-
163
-
-
49249136687
-
Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model
-
Feng, H.L.; Leng, Y.; Ma, C.H.; Zhang, J.; Ren, M.; Chuang, D.M. Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model. Neuroscience, 2008, 155, 567-72.
-
(2008)
Neuroscience
, vol.155
, pp. 567-572
-
-
Feng, H.L.1
Leng, Y.2
Ma, C.H.3
Zhang, J.4
Ren, M.5
Chuang, D.M.6
-
164
-
-
34548637868
-
Minocycline and riluzole brain disposition: Interactions with p-glycoprotein at the blood-brain barrier
-
Milane, A.; Fernandez, C.; Vautier, S.; Bensimon, G.; Meininger, V.; Farinotti, R. Minocycline and riluzole brain disposition: interactions with p-glycoprotein at the blood-brain barrier. J. Neurochem., 2007, 103, 164-73.
-
(2007)
J. NeuroChem
, vol.103
, pp. 164-173
-
-
Milane, A.1
Fernandez, C.2
Vautier, S.3
Bensimon, G.4
Meininger, V.5
Farinotti, R.6
-
165
-
-
70349305286
-
Brain and plasma riluzole pharmacokinetics: Effect of minocycline combination
-
Milane, A.; Tortolano, L.; Fernandez, C.; Bensimon, G.; Meininger, V.; Farinotti, R. Brain and plasma riluzole pharmacokinetics: effect of minocycline combination. J. Pharm. Pharmaceut. Sci., 2009, 12, 209-17.
-
(2009)
J. Pharm. Pharmaceut. Sci
, vol.12
, pp. 209-217
-
-
Milane, A.1
Tortolano, L.2
Fernandez, C.3
Bensimon, G.4
Meininger, V.5
Farinotti, R.6
-
166
-
-
0032692481
-
The ALSFRS-r: A revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS study group (phase III)
-
Cedarbaum, J.M.; Stambler, N.; Malta, E.; Fuller, C.; Hilt, D.; Thurmond, B.; Nakanishi, A. The ALSFRS-r: a revised ALS functional rating scale that incorporates assessments of respiratory function. BDNF ALS study group (phase III). J. Neurol. Sci., 1999, 169, 13-21.
-
(1999)
J. Neurol. Sci
, vol.169
, pp. 13-21
-
-
Cedarbaum, J.M.1
Stambler, N.2
Malta, E.3
Fuller, C.4
Hilt, D.5
Thurmond, B.6
Nakanishi, A.7
-
167
-
-
34548267752
-
Current clinical trials in amyotrophic lateral sclerosis
-
Bhatt, J.M.; Gordon, P.H. Current clinical trials in amyotrophic lateral sclerosis. Expert Opin. Investig. Drugs, 2007, 16, 1197-1207.
-
(2007)
Expert Opin. Investig. Drugs
, vol.16
, pp. 1197-1207
-
-
Bhatt, J.M.1
Gordon, P.H.2
-
169
-
-
8844220353
-
Functional outcome measures as clinical trial endpoints in ALS
-
Traynor, B.J.; Zhang, H.; Shefner, J.M.; Schoenfeld, D.; Cudkowicz, M.E.; Consortium, N. Functional outcome measures as clinical trial endpoints in ALS. Neurology, 2004, 63, 1933-5.
-
(2004)
Neurology
, vol.63
, pp. 1933-1935
-
-
Traynor, B.J.1
Zhang, H.2
Shefner, J.M.3
Schoenfeld, D.4
Cudkowicz, M.E.5
Consortium, N.6
-
170
-
-
46749128523
-
Designing clinical trials in amyotrophic lateral sclerosis
-
Shefner, J.M. Designing clinical trials in amyotrophic lateral sclerosis. Phys. Med. Rehabil. Clin. N. Am., 2008, 19, 495-508.
-
(2008)
Phys. Med. Rehabil. Clin. N. Am
, vol.19
, pp. 495-508
-
-
Shefner, J.M.1
-
171
-
-
67049145001
-
Defining survival as an outcome measure in amyotrophic lateral sclerosis
-
Gordon, P.H.; Corcia, P.; Lacomblez, L.; Pochigaeva, K.; Abitbol, J.L.; Cudkowicz, M.; Leigh, P.N.; Meininger, V. Defining survival as an outcome measure in amyotrophic lateral sclerosis. Arch. Neurol., 2009, 66, 758-61.
-
(2009)
Arch. NeuRol
, vol.66
, pp. 758-761
-
-
Gordon, P.H.1
Corcia, P.2
Lacomblez, L.3
Pochigaeva, K.4
Abitbol, J.L.5
Cudkowicz, M.6
Leigh, P.N.7
Meininger, V.8
-
172
-
-
46749128523
-
Designing clinical trials in amyotrophic lateral sclerosis
-
Shefner, J.M. Designing clinical trials in amyotrophic lateral sclerosis. Phys. Med. Rehabil. Clin. N. Am., 2008, 19, 495-508.
-
(2008)
Phys. Med. Rehabil. Clin. N. Am
, vol.19
, pp. 495-508
-
-
Shefner, J.M.1
-
173
-
-
72849182647
-
Quantitative muscle testing: Principles and applications to research and clinical services
-
Beasley, W.C. Quantitative muscle testing: principles and applications to research and clinical services. Arch. Phys. Med. Rehabil., 1961, 42, 398-425.
-
(1961)
Arch. Phys. Med. Rehabil
, vol.42
, pp. 398-425
-
-
Beasley, W.C.1
-
174
-
-
33748646774
-
Effect of riluzole on Ca2+ movement and cytotoxicity in madin-darby canine kidney cells
-
Chen, W.C.; Cheng, H.H.; Huang, C.J.; Chou, C.T.; Liu, S.I.; Chen, I.S.; Hsu, S.S.; Chang, H.T.; Huang, J.K.; Jan, CR. Effect of riluzole on Ca2+ movement and cytotoxicity in madin-darby canine kidney cells. Hum. Exp. Toxicol., 2006, 25, 461-9.
-
(2006)
Hum. Exp. Toxicol
, vol.25
, pp. 461-469
-
-
Chen, W.C.1
Cheng, H.H.2
Huang, C.J.3
Chou, C.T.4
Liu, S.I.5
Chen, I.S.6
Hsu, S.S.7
Chang, H.T.8
Huang, J.K.9
Jan, C.R.10
-
175
-
-
0036420587
-
Effect of riluzole on cytosolic Ca2+ increase in human osteosarcoma cells
-
Jan, C.R.; Lu, Y.C.; Jiann, B.P.; Chang, H.T.; Huang, J.K. Effect of riluzole on cytosolic Ca2+ increase in human osteosarcoma cells. Pharmacology, 2002, 66, 120-7.
-
(2002)
Pharmacology
, vol.66
, pp. 120-127
-
-
Jan, C.R.1
Lu, Y.C.2
Jiann, B.P.3
Chang, H.T.4
Huang, J.K.5
-
176
-
-
0034982187
-
Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells
-
Wang, J.L.; Lee, K.C.; Tang, K.Y.; Lu, T.; Chang, C.H.; Chow, C.K.; Chen, W.C.; Su, W.; Law, Y.P.; Jan, C.R. Effect of the neuroprotective agent riluzole on intracellular Ca2+ levels in IMR32 neuroblastoma cells. Arch. Toxicol., 2001, 75, 214-20.
-
(2001)
Arch. Toxicol
, vol.75
, pp. 214-220
-
-
Wang, J.L.1
Lee, K.C.2
Tang, K.Y.3
Lu, T.4
Chang, C.H.5
Chow, C.K.6
Chen, W.C.7
Su, W.8
Law, Y.P.9
Jan, C.R.10
-
177
-
-
0033777816
-
Protective effects of riluzole on dopamine neurons: Involvement of oxidative stress and cellular energy metabolism
-
Storch, A.; Burkhardt, K.; Ludolph, A.C.; Schwarz, J. Protective effects of riluzole on dopamine neurons: involvement of oxidative stress and cellular energy metabolism. J. Neurochem., 2000, 75, 2259-69.
-
(2000)
J. Neurochem
, vol.75
, pp. 2259-2269
-
-
Storch, A.1
Burkhardt, K.2
Ludolph, A.C.3
Schwarz, J.4
-
178
-
-
70449697216
-
Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: A doubleblind, randomized, multicentre, placebo-controlled trial
-
Meininger, V.; Drory, V.E.; Leigh, P.N.; Ludolph, A.; Robberecht, W.; Silani, V. Glatiramer acetate has no impact on disease progression in ALS at 40 mg/day: a doubleblind, randomized, multicentre, placebo-controlled trial. Amyotroph. Lateral Scler., 2009, 10, 378-83.
-
(2009)
Amyotroph. Lateral Scler
, vol.10
, pp. 378-383
-
-
Meininger, V.1
Drory, V.E.2
Leigh, P.N.3
Ludolph, A.4
Robberecht, W.5
Silani, V.6
-
179
-
-
0036829010
-
From chemical to drug: Neurodegeneration drug screening and the ethics of clinical trials
-
Heemskerk, J.; Tobin, A.J.; Ravina, B. From chemical to drug: neurodegeneration drug screening and the ethics of clinical trials. Nat. Neurosci., 2002, 5, 1027-9.
-
(2002)
Nat. Neurosci
, vol.5
, pp. 1027-1029
-
-
Heemskerk, J.1
Tobin, A.J.2
Ravina, B.3
-
180
-
-
36148996513
-
Learning from failed trials in ALS
-
Swash, M. Learning from failed trials in ALS. Lancet Neurol., 2007, 6, 1034-5.
-
(2007)
Lancet Neurol
, vol.6
, pp. 1034-1035
-
-
Swash, M.1
-
181
-
-
49649095887
-
Neuroscience: Standard model
-
Schnabel, J. Neuroscience: standard model. Nature, 2008, 454, 682-5.
-
(2008)
Nature
, vol.454
, pp. 682-685
-
-
Schnabel, J.1
-
182
-
-
0037007645
-
Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice
-
Zhu, S.; Stavrovskaya, I.G.; Drozda, M.; Kim, B.Y.; Ona, V.; Li, M.; Sarang, S.; Liu, A.S.; Hartley, D.M.; Wu, D.C.; Gullans, S.; Ferrante, R.J.; Przedborski, S.; Kristal, B.S.; Friedlander, R.M. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature, 2002, 417, 74-8.
-
(2002)
Nature
, vol.417
, pp. 74-78
-
-
Zhu, S.1
Stavrovskaya, I.G.2
Drozda, M.3
Kim, B.Y.4
Ona, V.5
Li, M.6
Sarang, S.7
Liu, A.S.8
Hartley, D.M.9
Wu, D.C.10
Gullans, S.11
Ferrante, R.J.12
Przedborski, S.13
Kristal, B.S.14
Friedlander, R.M.15
-
183
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
Klivenyi, P.; Ferrante, R.J.; Matthews, R.T.; Bogdanov, M.B.; Klein, A.M.; Andreassen, O.A.; Mueller, G.; Wermer, M.; Kaddurah-Daouk, R.; Beal, M.F. Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat. Med., 1999, 5, 347-50.
-
(1999)
Nat. Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
184
-
-
8644289377
-
NEALS Consortium. A clinical trial of creatine in ALS
-
Shefner, J.M.; Cudkowicz, M.E.; Schoenfeld, D.; Conrad, T.; Taft, J.; Chilton, M.; Urbinelli, L.; Qureshi, M.; Zhang, H.; Pestronk, A.; Caress, J.; Donofrio, P.; Sorenson, E.; Bradley, W.; Lomen-Hoerth, C.; Pioro, E.; Rezania, K.; Ross, M.; Pascuzzi, R.; Heiman-Patterson, T.; Tandan, R.; Mitsumoto, H.; Rothstein, J.; Smith-Palmer, T.; MacDonald, D.; Burke, D.; NEALS Consortium. A clinical trial of creatine in ALS. Neurology, 2004, 63, 1656-61.
-
(2004)
Neurology
, vol.63
, pp. 1656-1661
-
-
Shefner, J.M.1
Cudkowicz, M.E.2
Schoenfeld, D.3
Conrad, T.4
Taft, J.5
Chilton, M.6
Urbinelli, L.7
Qureshi, M.8
Zhang, H.9
Pestronk, A.10
Caress, J.11
Donofrio, P.12
Sorenson, E.13
Bradley, W.14
Lomen-Hoerth, C.15
Pioro, E.16
Rezania, K.17
Ross, M.18
Pascuzzi, R.19
Heiman-Patterson, T.20
Tandan, R.21
Mitsumoto, H.22
Rothstein, J.23
Smith-Palmer, T.24
Macdonald, D.25
Burke, D.26
more..
-
185
-
-
0037379650
-
A randomized sequential trial of creatine in amyotrophic lateral sclerosis
-
Groeneveld, G.J.; Veldink, J.H.; van der Tweel, I.; Kalmijn, S.; Beijer, C.; de Visser, M.; Wokke, J.H.J.; Franssen, H.; van den Berg, L.H. A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann. Neurol., 2003, 53, 437-45.
-
(2003)
Ann. Neurol
, vol.53
, pp. 437-445
-
-
Groeneveld, G.J.1
Veldink, J.H.2
van der Tweel, I.3
Kalmijn, S.4
Beijer, C.5
de Visser, M.6
Wokke, J.H.J.7
Franssen, H.8
van den Berg, L.H.9
-
186
-
-
33645331591
-
Assessment of cortical excitability using threshold tracking techniques
-
Vucic, S.; Howells, J.; Trevillion, L.; Kiernan, M.C. Assessment of cortical excitability using threshold tracking techniques. Muscle Nerve, 2006, 33, 477-86.
-
(2006)
Muscle Nerve
, vol.33
, pp. 477-486
-
-
Vucic, S.1
Howells, J.2
Trevillion, L.3
Kiernan, M.C.4
-
187
-
-
33749239968
-
Novel threshold tracking techniques suggest that cortical hyperexcitability is an early feature of motor neuron disease
-
Vucic, S.; Kiernan, M.C. Novel threshold tracking techniques suggest that cortical hyperexcitability is an early feature of motor neuron disease. Brain, 2006, 129, 2436-46.
-
(2006)
Brain
, vol.129
, pp. 2436-2446
-
-
Vucic, S.1
Kiernan, M.C.2
-
188
-
-
0027446580
-
Cortical excitability in amyotrophic lateral sclerosis: A clue to pathogenesis
-
Eisen, A.; Pant, B.; Stewart, H. Cortical excitability in amyotrophic lateral sclerosis: a clue to pathogenesis. Can. J. Neurol. Sci., 1993, 20, 11-6.
-
(1993)
Can. J. Neurol. Sci
, vol.20
, pp. 11-16
-
-
Eisen, A.1
Pant, B.2
Stewart, H.3
-
189
-
-
44949243975
-
Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis
-
Vucic, S.; Nicholson, G.A.; Kiernan, M.C. Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis. Brain, 2008, 131, 1540-50.
-
(2008)
Brain
, vol.131
, pp. 1540-1550
-
-
Vucic, S.1
Nicholson, G.A.2
Kiernan, M.C.3
-
190
-
-
0036848084
-
Different mechanisms contribute to motor cortex hyperexcitability in amyotrophic lateral sclerosis
-
Zanette, G.; Tamburin, S.; Manganotti, P.; Refatti, N.; Forgione, A.; Rizzuto, N. Different mechanisms contribute to motor cortex hyperexcitability in amyotrophic lateral sclerosis. Clin. Neurophysiol., 2002, 113, 1688-97.
-
(2002)
Clin. Neurophysiol
, vol.113
, pp. 1688-1697
-
-
Zanette, G.1
Tamburin, S.2
Manganotti, P.3
Refatti, N.4
Forgione, A.5
Rizzuto, N.6
-
191
-
-
58149527805
-
Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis
-
Pieri, M.; Carunchio, I.; Curcio, L.; Mercuri, N.B.; Zona, C. Increased persistent sodium current determines cortical hyperexcitability in a genetic model of amyotrophic lateral sclerosis. Exp. Neurol. 2009, 215, 368-79.
-
(2009)
Exp. Neurol
, vol.215
, pp. 368-379
-
-
Pieri, M.1
Carunchio, I.2
Curcio, L.3
Mercuri, N.B.4
Zona, C.5
-
192
-
-
0028945380
-
Functional availability of sodium channels modulated by cytosolic free Ca2+ in cultured mammalian neurons (N1E-115)
-
Bulatko, A.K.; Greeff, N.G. Functional availability of sodium channels modulated by cytosolic free Ca2+ in cultured mammalian neurons (N1E-115). J. Physiol., 1995, 484, 307-12.
-
(1995)
J. Physiol
, vol.484
, pp. 307-312
-
-
Bulatko, A.K.1
Greeff, N.G.2
-
193
-
-
33749625643
-
Increased nodal persistent Na+ currents in human neuropathy and motor neuron disease estimated by latent addition
-
Tamura, N.; Kuwabara, S.; Misawa, S.; Kanai, K.; Nakata, M.; Sawai, S.; Hattori, T. Increased nodal persistent Na+ currents in human neuropathy and motor neuron disease estimated by latent addition. Clin. Neurophysiol., 2006, 117, 2451-8.
-
(2006)
Clin. Neurophysiol
, vol.117
, pp. 2451-2458
-
-
Tamura, N.1
Kuwabara, S.2
Misawa, S.3
Kanai, K.4
Nakata, M.5
Sawai, S.6
Hattori, T.7
-
194
-
-
0036844866
-
Distinctive abnormalities of motor axonal strength-duration properties in multifocal motor neuropathy and in motor neurone disease
-
Priori, A.; Cinnante, C.; Pesenti, A.; Carpo, M.; Cappellari, A.; Nobile-Orazio, E.; Scarlato, G.; Barbieri, S. Distinctive abnormalities of motor axonal strength-duration properties in multifocal motor neuropathy and in motor neurone disease. Brain, 2002, 125, 2481-90.
-
(2002)
Brain
, vol.125
, pp. 2481-2490
-
-
Priori, A.1
Cinnante, C.2
Pesenti, A.3
Carpo, M.4
Cappellari, A.5
Nobile-Orazio, E.6
Scarlato, G.7
Barbieri, S.8
-
195
-
-
0031898458
-
Strengthduration properties of sensory and motor axons in amyotrophic lateral sclerosis
-
Mogyoros, I.; Kiernan, M.C.; Burke, D.; Bostock, H. Strengthduration properties of sensory and motor axons in amyotrophic lateral sclerosis. Brain, 1998, 121, 851-9.
-
(1998)
Brain
, vol.121
, pp. 851-859
-
-
Mogyoros, I.1
Kiernan, M.C.2
Burke, D.3
Bostock, H.4
-
196
-
-
33745418427
-
Axonal excitability properties in amyotrophic lateral sclerosis
-
Vucic, S.; Kiernan, M.C. Axonal excitability properties in amyotrophic lateral sclerosis. Clin. Neurophysiol., 2006, 117, 1458-66.
-
(2006)
Clin. Neurophysiol
, vol.117
, pp. 1458-1466
-
-
Vucic, S.1
Kiernan, M.C.2
-
197
-
-
33645075174
-
Altered axonal excitability properties in amyotrophic lateral sclerosis: Impaired potassium channel function related to disease stage
-
Kanai, K.; Kuwabara, S.; Misawa, S.; Tamura, N.; Ogawara, K.; Nakata, M.; Sawai, S.; Hattori, T.; Bostock, H. Altered axonal excitability properties in amyotrophic lateral sclerosis: impaired potassium channel function related to disease stage. Brain, 2006, 129, 953-62.
-
(2006)
Brain
, vol.129
, pp. 953-962
-
-
Kanai, K.1
Kuwabara, S.2
Misawa, S.3
Tamura, N.4
Ogawara, K.5
Nakata, M.6
Sawai, S.7
Hattori, T.8
Bostock, H.9
-
198
-
-
33751542967
-
Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis
-
Zona, C.; Pieri, M.; Carunchio, I. Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis. J. Neurophysiol., 2006, 96, 3314-22.
-
(2006)
J. Neurophysiol
, vol.96
, pp. 3314-3322
-
-
Zona, C.1
Pieri, M.2
Carunchio, I.3
-
199
-
-
0026556810
-
Ionic mechanisms of anoxic injury in mammalian CNS white matter: Role of Na+ channels and Na+-Ca2+ exchanger
-
Stys, P.K.; Waxman, S.G.; Ransom, B.R. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na+-Ca2+ exchanger. J. Neurosci., 1992, 12, 430-9.
-
(1992)
J. Neurosci
, vol.12
, pp. 430-439
-
-
Stys, P.K.1
Waxman, S.G.2
Ransom, B.R.3
-
200
-
-
0026396032
-
Reverse operation of the Na+-Ca2+ Exchanger Mediates Ca2+ Influx During Anoxia In MamMalian CNS White Matter
-
Stys, P.K.; Waxman, S.G.; Ransom, B.R. Reverse operation of the Na+-Ca2+ exchanger mediates Ca2+ influx during anoxia in mammalian CNS white matter. Ann. N. Y. Acad. Sci., 1991, 639, 328-332.
-
(1991)
Ann. N. Y. Acad. Sci
, vol.639
, pp. 328-332
-
-
Stys, P.K.1
Waxman, S.G.2
Ransom, B.R.3
-
201
-
-
40549135991
-
Mechanisms of disease: Sodium channels and neuroprotection in multiple sclerosis-current status
-
Waxman, S.G. Mechanisms of disease: sodium channels and neuroprotection in multiple sclerosis-current status. Nat. Clin. Pract. Neurol., 2008, 4, 159-69.
-
(2008)
Nat. Clin. Pract. Neurol
, vol.4
, pp. 159-169
-
-
Waxman, S.G.1
-
202
-
-
0035067635
-
Electrically active axons degenerate when exposed to nitric oxide
-
Smith, K.J.; Kapoor, R.; Hall, S.M.; Davies M. Electrically active axons degenerate when exposed to nitric oxide. Ann. Neurol., 2001, 49, 470-6.
-
(2001)
Ann. Neurol
, vol.49
, pp. 470-476
-
-
Smith, K.J.1
Kapoor, R.2
Hall, S.M.3
Davies, M.4
-
203
-
-
0037309442
-
Blockers of sodium and calcium entry protect axons from nitric ox-ide-mediated degeneration
-
Kapoor, R.; Davies, M.; Blaker, P.A.; Hall, S.M.; Smith, K.J. Blockers of sodium and calcium entry protect axons from nitric ox-ide-mediated degeneration. Ann. Neurol., 2003, 53, 174-80.
-
(2003)
Ann. Neurol
, vol.53
, pp. 174-180
-
-
Kapoor, R.1
Davies, M.2
Blaker, P.A.3
Hall, S.M.4
Smith, K.J.5
-
204
-
-
33744489487
-
Axonal protection achieved in a model of multiple sclerosis using lamotrigine
-
Bechtold, D.A.; Miller, S.J.; Dawson, A.C.; Sun, Y.; Kapoor, R.; Berry, D.; Smith, K.J. Axonal protection achieved in a model of multiple sclerosis using lamotrigine. J. Neurol., 2006, 253, 1542-1551.
-
(2006)
J. Neurol
, vol.253
, pp. 1542-1551
-
-
Bechtold, D.A.1
Miller, S.J.2
Dawson, A.C.3
Sun, Y.4
Kapoor, R.5
Berry, D.6
Smith, K.J.7
-
205
-
-
2142760098
-
Axonal protection using flecainide in experimental autoimmune encephalomyelitis
-
Bechtold, D.A.; Kapoor, R.; Smith, K.J. Axonal protection using flecainide in experimental autoimmune encephalomyelitis. Ann. Neurol., 2004; 55, 607-16.
-
(2004)
Ann. Neurol
, vol.55
, pp. 607-616
-
-
Bechtold, D.A.1
Kapoor, R.2
Smith, K.J.3
-
206
-
-
11244260444
-
Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide
-
Bechtold, D.A.; Yue, X.; Evans, R.M.; Davies, M.; Gregson, N.A.; Smith, K.J. Axonal protection in experimental autoimmune neuritis by the sodium channel blocking agent flecainide. Brain, 2005, 128, 18-28.
-
(2005)
Brain
, vol.128
, pp. 18-28
-
-
Bechtold, D.A.1
Yue, X.2
Evans, R.M.3
Davies, M.4
Gregson, N.A.5
Smith, K.J.6
-
207
-
-
59949106172
-
Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis
-
Trapp, B.D.; Stys, P.K. Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis. Lancet Neurol., 2009, 8, 280-91.
-
(2009)
Lancet Neurol
, vol.8
, pp. 280-291
-
-
Trapp, B.D.1
Stys, P.K.2
-
208
-
-
35748955508
-
Fatigue and activity dependent changes in axonal excitability in amyotrophic lateral sclerosis
-
Vucic, S.; Krishnan, A.V.; Kiernan, M.C. Fatigue and activity dependent changes in axonal excitability in amyotrophic lateral sclerosis. J. Neurol. Neurosurg. Psychiatry, 2007, 78, 1202-8.
-
(2007)
J. Neurol. Neurosurg. Psychiatry
, vol.78
, pp. 1202-1208
-
-
Vucic, S.1
Krishnan, A.V.2
Kiernan, M.C.3
-
209
-
-
0037221596
-
Global loss of Na+/K+-ATPase and Its Nitric Oxide-mediated Regulation In a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis
-
Ellis, D.Z.; Rabe, J.; Sweadner, K.J. Global loss of Na+/K+-ATPase and its nitric oxide-mediated regulation in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci., 2003, 23, 43-51.
-
(2003)
J. Neurosci
, vol.23
, pp. 43-51
-
-
Ellis, D.Z.1
Rabe, J.2
Sweadner, K.J.3
-
211
-
-
19944428649
-
β-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
-
Rothstein, J.D.; Patel, S.; Regan, M.R.; Haenggeli, C.; Huang, Y.H.; Bergles, D.E.; Jin, L, Dykes Hoberg, M.; Vidensky, S.; Chung, D.S.; Toan, S.V.; Bruijn, L.I.; Su, Z.Z.; Gupta, P.; Fisher, P.B. -lactam antibiotics offer neuroprotection by increasing glutamate transporter expression. Nature, 2005, 433, 73-7.
-
(2005)
Nature
, vol.433
, pp. 73-77
-
-
Rothstein, J.D.1
Patel, S.2
Regan, M.R.3
Haenggeli, C.4
Huang, Y.H.5
Bergles, D.E.6
Jin, L.7
Dykes Hoberg, M.8
Vidensky, S.9
Chung, D.S.10
Toan, S.V.11
Bruijn, L.I.12
Su, Z.Z.13
Gupta, P.14
Fisher, P.B.15
-
212
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska, I.; Bell, S.; Cairns, N.J.; Miller, T.M.; Baloh, R.H. TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 18809-14.
-
(2009)
Proc. Natl. Acad. Sci. U.S.A
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
213
-
-
0031239776
-
Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: Implications for neuroprotective strategies
-
Stefani, A.; Spadoni, F.; Bernardi, G. Differential inhibition by riluzole, lamotrigine, and phenytoin of sodium and calcium currents in cortical neurons: implications for neuroprotective strategies. Exp. Neurol., 1997, 147, 115-22.
-
(1997)
Exp. Neurol
, vol.147
, pp. 115-122
-
-
Stefani, A.1
Spadoni, F.2
Bernardi, G.3
-
214
-
-
0030886021
-
Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons
-
Huang, C-S.; Song, J-H.; Nagata, K.; Yeh, J.Z.; Narahashi, T. Effects of the neuroprotective agent riluzole on the high voltage-activated calcium channels of rat dorsal root ganglion neurons. J. Pharmacol. Exp. Ther., 1997, 282, 1280-90.
-
(1997)
J. Pharmacol. Exp. Ther
, vol.282
, pp. 1280-1290
-
-
Huang, C.-S.1
Song, J.-H.2
Nagata, K.3
Yeh, J.Z.4
Narahashi, T.5
-
215
-
-
0037007984
-
Lamotrigine derivatives and riluzole inhibit iNap in cortical neurons
-
Spadoni, F.; Hainsworth, A.H.; Mercuri, N.B.; Caputi, L.; Martella, G.; Lavaroni, F.; Bernardi, G.; Stefani, A. Lamotrigine derivatives and riluzole inhibit iNap in cortical neurons. Neuroreport, 2002, 13, 1167-70.
-
(2002)
Neuroreport
, vol.13
, pp. 1167-1170
-
-
Spadoni, F.1
Hainsworth, A.H.2
Mercuri, N.B.3
Caputi, L.4
Martella, G.5
Lavaroni, F.6
Bernardi, G.7
Stefani, A.8
-
216
-
-
0031901783
-
Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons
-
Zona, C.; Siniscalchi, A.; Mercuri, N.B.; Bernardi, G. Riluzole interacts with voltage-activated sodium and potassium currents in cultured rat cortical neurons. Neuroscience, 1998, 85, 931-8.
-
(1998)
Neuroscience
, vol.85
, pp. 931-938
-
-
Zona, C.1
Siniscalchi, A.2
Mercuri, N.B.3
Bernardi, G.4
-
217
-
-
67649563641
-
A riluzole-and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones
-
Lamas, J.A.; Romero, M.; Reboreda, A.; Sanchez, E.; Ribeiro, S.J. A riluzole and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones. Pflügers Arch., 2009, 458, 589-99.
-
(2009)
Pflügers Arch
, vol.458
, pp. 589-599
-
-
Lamas, J.A.1
Romero, M.2
Reboreda, A.3
Sanchez, E.4
Ribeiro, S.J.5
-
218
-
-
0344873161
-
Riluzole inhibits spontaneous Ca2+ signaling in neuroendocrine cells by activation of K+ channels and inhibition of Na+ channels
-
Beltran-Parrazal, L, Charles, A. Riluzole inhibits spontaneous Ca2+ signaling in neuroendocrine cells by activation of K+ channels and inhibition of Na+ channels. Br. J. Pharmacol., 2003, 140, 881-8.
-
(2003)
Br. J. Pharmacol
, vol.140
, pp. 881-888
-
-
Beltran-Parrazal, L.1
Charles, A.2
-
219
-
-
34249096118
-
Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice
-
Irifune, M.; Kikuchi, N.; Saida, T.; Takarada, T.; Shimizu, Y.; Endo, C.; Morita, K.; Dohi, T.; Sato, T.; Kawahara, M. Riluzole, a glutamate release inhibitor, induces loss of righting reflex, antinociception, and immobility in response to noxious stimulation in mice. Anesth. Analg., 2007, 104, 1415-21.
-
(2007)
Anesth. Analg
, vol.104
, pp. 1415-1421
-
-
Irifune, M.1
Kikuchi, N.2
Saida, T.3
Takarada, T.4
Shimizu, Y.5
Endo, C.6
Morita, K.7
Dohi, T.8
Sato, T.9
Kawahara, M.10
-
220
-
-
0034722096
-
Anesthetic concentrations of riluzole inhibit neuronal nitric oxide synthase activity, but not expression, in the rat hippocampus
-
Keita, H.; Boczkowski, J.; Samb, A.; Lanone, S.; Lang-Lazdunski, L.; Rouelle, D.; Desmonts, J.M.; Mantz, J. Anesthetic concentrations of riluzole inhibit neuronal nitric oxide synthase activity, but not expression, in the rat hippocampus. Brain Res., 2000, 881, 237-40.
-
(2000)
Brain Res
, vol.881
, pp. 237-240
-
-
Keita, H.1
Boczkowski, J.2
Samb, A.3
Lanone, S.4
Lang-Lazdunski, L.5
Rouelle, D.6
Desmonts, J.M.7
Mantz, J.8
|