메뉴 건너뛰기




Volumn 32, Issue 3, 1999, Pages 147-152

Neuroprotective effects of riluzole: An electrophysiological and histological analysis in an in vitro model of ischemia

Author keywords

Cerebral cortex; Field potential; Glucose and O2 deprivation; Neuronal death; Synaptic transmission

Indexed keywords

GLUCOSE; OXYGEN; RILUZOLE;

EID: 0033151391     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1098-2396(19990601)32:3<147::AID-SYN1>3.0.CO;2-P     Document Type: Article
Times cited : (26)

References (38)
  • 1
    • 0019409427 scopus 로고
    • Increase in extracellular potassium in the brain during circulatory arrest: Effects hypothermia, lidocaine and thiopental
    • Astrup A, Skovsted P, Gjerris F, Soresen H R. 1981. Increase in extracellular potassium in the brain during circulatory arrest: effects hypothermia, lidocaine and thiopental. Anesthesiology 55: 256-262.
    • (1981) Anesthesiology , vol.55 , pp. 256-262
    • Astrup, A.1    Skovsted, P.2    Gjerris, F.3    Soresen, H.R.4
  • 2
    • 0028296887 scopus 로고
    • Lidocaine delays cortical ischemic depolarization: Relationship to electrophysiologic recovery and neuropathology
    • Ayad M, Verity MA, Rubinstein E H. 1994. Lidocaine delays cortical ischemic depolarization: relationship to electrophysiologic recovery and neuropathology. Anesthesiology 6:98-110.
    • (1994) Anesthesiology , vol.6 , pp. 98-110
    • Ayad, M.1    Verity, M.A.2    Rubinstein, E.H.3
  • 4
    • 0026334826 scopus 로고
    • + channels in myelinated nerve fibre
    • + channels in myelinated nerve fibre. Pflugers Arch 419:603-609.
    • (1991) Pflugers Arch , vol.419 , pp. 603-609
    • Benoit, E.1    Escande, D.2
  • 5
    • 0029812585 scopus 로고    scopus 로고
    • A field potential analysis on the effect of lamotrigine, GP 4779, and felbamate in neocortical slices
    • Calabresi P, Siniscalchi A, Pisani A, Stefani A, Mercuri NB, Bernardi G. 1996. A field potential analysis on the effect of lamotrigine, GP 4779, and felbamate in neocortical slices. Neurology 47:557-562.
    • (1996) Neurology , vol.47 , pp. 557-562
    • Calabresi, P.1    Siniscalchi, A.2    Pisani, A.3    Stefani, A.4    Mercuri, N.B.5    Bernardi, G.6
  • 6
    • 0026490217 scopus 로고
    • Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo
    • Cheramy A, Barbeito L, Godeheu G, Glowinski J. 1992. Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neurosci Lett 147:209-212.
    • (1992) Neurosci Lett , vol.147 , pp. 209-212
    • Cheramy, A.1    Barbeito, L.2    Godeheu, G.3    Glowinski, J.4
  • 7
    • 0025265926 scopus 로고
    • The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
    • Choi DW, Rothman SM. 1990. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 13:171-182.
    • (1990) Annu Rev Neurosci , vol.13 , pp. 171-182
    • Choi, D.W.1    Rothman, S.M.2
  • 8
    • 0027745843 scopus 로고
    • Membrane currents in CA1 hippocampal cells during spreading depression (SD) and SD-like hypoxic depolarization
    • Czeh G, Aitken PG, Somjen GG.1993. Membrane currents in CA1 hippocampal cells during spreading depression (SD) and SD-like hypoxic depolarization. Brain Res 632:195-208.
    • (1993) Brain Res , vol.632 , pp. 195-208
    • Czeh, G.1    Aitken, P.G.2    Somjen, G.G.3
  • 9
    • 0027213025 scopus 로고
    • Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in xenopus oocytes
    • Debono MW, Le Guern J, Canton T, Doble A, Praider L. 1993. Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes. Eur J Pharmacol 235:283-289.
    • (1993) Eur J Pharmacol , vol.235 , pp. 283-289
    • Debono, M.W.1    Le Guern, J.2    Canton, T.3    Doble, A.4    Praider, L.5
  • 10
    • 0026663768 scopus 로고
    • Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on d-aspartate release from cultured cerebellar granule cells
    • Doble A, Hebert JP, Blanchard JC. 1992. Pertussis toxin pretreatment abolishes the inhibitory effect of riluzole and carbachol on d-aspartate release from cultured cerebellar granule cells. Neurosci Lett 140:251-254.
    • (1992) Neurosci Lett , vol.140 , pp. 251-254
    • Doble, A.1    Hebert, J.P.2    Blanchard, J.C.3
  • 11
    • 0021829328 scopus 로고
    • Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro
    • Drejer J, Benveniste H, Diemer NH, Schousboe A. 1985. Cellular origin of ischemia-induced glutamate release from brain tissue in vivo and in vitro. J Neurochem 45:145-151.
    • (1985) J Neurochem , vol.45 , pp. 145-151
    • Drejer, J.1    Benveniste, H.2    Diemer, N.H.3    Schousboe, A.4
  • 12
    • 0029610441 scopus 로고
    • The importance of sodium for anoxic transmission damage in rat hippocampal slices: Mechanisms of protection by lidocaine
    • Fried E, Amorim, P, Chambers G, Cottrell JE, Kass IS. 1995. The importance of sodium for anoxic transmission damage in rat hippocampal slices: mechanisms of protection by lidocaine. J Physiol 489:557-565.
    • (1995) J Physiol , vol.489 , pp. 557-565
    • Fried, E.1    Amorim, P.2    Chambers, G.3    Cottrell, J.E.4    Kass, I.S.5
  • 13
    • 0027340070 scopus 로고
    • 2 deprivation in the central nervous system: On mechanisms of neuronal response, differential sensitivity and injury
    • 2 deprivation in the central nervous system: on mechanisms of neuronal response, differential sensitivity and injury. Prog Neurobiol 40:277-318.
    • (1992) Prog Neurobiol , vol.40 , pp. 277-318
    • Haddad, G.G.1    Jiang, C.2
  • 14
    • 0029866067 scopus 로고    scopus 로고
    • Hypertonic environment prevents depolarization and improves functional recovery from hypoxia in hippocampal slices
    • Huang R, Aitken PG, Somjen GG. 1996. Hypertonic environment prevents depolarization and improves functional recovery from hypoxia in hippocampal slices. J Cereb Blood Flow Metab 16:462-467.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 462-467
    • Huang, R.1    Aitken, P.G.2    Somjen, G.G.3
  • 15
    • 0028058808 scopus 로고
    • Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: Evidence for a dual mechanism of action
    • Hubert JP, Delemeau JC, Glowinski J, Premont J, Doble A. 1994. Antagonism by riluzole of entry of calcium evoked by NMDA and veratridine in rat cultured granule cells: evidence for a dual mechanism of action. Br J Pharmacol 113:261-267.
    • (1994) Br J Pharmacol , vol.113 , pp. 261-267
    • Hubert, J.P.1    Delemeau, J.C.2    Glowinski, J.3    Premont, J.4    Doble, A.5
  • 16
    • 0027310109 scopus 로고
    • Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex
    • Lees G, Leach MJ. 1993. Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex. Brain Res 612:190-199.
    • (1993) Brain Res , vol.612 , pp. 190-199
    • Lees, G.1    Leach, M.J.2
  • 17
    • 0027443742 scopus 로고
    • Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: Relationship to electrophysiological cell damage
    • Lobner D, Lipton P. 1993. Intracellular calcium levels and calcium fluxes in the CA1 region of the rat hippocampal slice during in vitro ischemia: relationship to electrophysiological cell damage. J Neurosci 13:4861-4871.
    • (1993) J Neurosci , vol.13 , pp. 4861-4871
    • Lobner, D.1    Lipton, P.2
  • 18
    • 0026691462 scopus 로고
    • Hypoxia-induced functional alterations in adult rat neocortex
    • Luhmann HJ, Heinemann U. 1992. Hypoxia-induced functional alterations in adult rat neocortex. J Neurophysiol 67:798-811.
    • (1992) J Neurophysiol , vol.67 , pp. 798-811
    • Luhmann, H.J.1    Heinemann, U.2
  • 19
    • 0028940581 scopus 로고
    • Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists
    • Lynch JJ, Yu SP, Canzoniero LTM, Sensi SL, Choi DW. 1995. Sodium channel blockers reduce oxygen-glucose deprivation-induced cortical neuronal injury when combined with glutamate receptor antagonists. J Pharmacol Exp Ther 273:554-560.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 554-560
    • Lynch, J.J.1    Yu, S.P.2    Canzoniero, L.T.M.3    Sensi, S.L.4    Choi, D.W.5
  • 21
    • 0027762836 scopus 로고
    • The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1
    • Martin D, Thompson MA, Nadler JV. 1993. The neuroprotective agent riluzole inhibits release of glutamate and aspartate from slices of hippocampal area CA1. Eur J Pharmacol 250:473-476.
    • (1993) Eur J Pharmacol , vol.250 , pp. 473-476
    • Martin, D.1    Thompson, M.A.2    Nadler, J.V.3
  • 22
    • 0028335125 scopus 로고
    • The early events of oxygen and glucose deprivation : Setting the scene for neuronal death?
    • Martin RL, Lloyd HGE, Cowan AI. 1994. The early events of oxygen and glucose deprivation : setting the scene for neuronal death? Trends Neurosci 17:251-257.
    • (1994) Trends Neurosci , vol.17 , pp. 251-257
    • Martin, R.L.1    Lloyd, H.G.E.2    Cowan, A.I.3
  • 23
    • 0025390880 scopus 로고
    • Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission
    • Meldrum BS. 1990. Protection against ischaemic neuronal damage by drugs acting on excitatory neurotransmission. Cerebrovasc Brain Metab Rev 2:27-57.
    • (1990) Cerebrovasc Brain Metab Rev , vol.2 , pp. 27-57
    • Meldrum, B.S.1
  • 27
    • 0024386187 scopus 로고
    • The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury
    • Roman R, Bartkowski H, Simon RP. 1989. The specific NMDA receptor antagonist AP-7 attenuates focal ischemic brain injury. Neurosci Lett 104:19-24.
    • (1989) Neurosci Lett , vol.104 , pp. 19-24
    • Roman, R.1    Bartkowski, H.2    Simon, R.P.3
  • 28
    • 0023219060 scopus 로고
    • Excitotoxicity and the NMDA receptor
    • Rothman SM, Olney JW. 1987. Excitotoxicity and the NMDA receptor. Trends Neurosci 10:299-302.
    • (1987) Trends Neurosci , vol.10 , pp. 299-302
    • Rothman, S.M.1    Olney, J.W.2
  • 29
    • 0024556434 scopus 로고
    • Calcium fluxes, calcium antagonists and calcium-related pathology in brain ischemia, hypoglycemia and spreading depression: A unifying hypothesis
    • Siesjo BK, Bengtsson F. 1989. Calcium fluxes, calcium antagonists and calcium-related pathology in brain ischemia, hypoglycemia and spreading depression: a unifying hypothesis. J Cereb Blood Flow Metab 9:127-140.
    • (1989) J Cereb Blood Flow Metab , vol.9 , pp. 127-140
    • Siesjo, B.K.1    Bengtsson, F.2
  • 30
    • 0025309389 scopus 로고
    • N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism
    • Simon RP, Shirashi K. 1990. N-methyl-D-aspartate antagonist reduces stroke size and regional glucose metabolism. Ann Neurol 27:606-611.
    • (1990) Ann Neurol , vol.27 , pp. 606-611
    • Simon, R.P.1    Shirashi, K.2
  • 31
    • 0031036733 scopus 로고    scopus 로고
    • Effects of riluzole on rat cortical neurons: An in vitro electrophysiological study
    • Siniscalchi A, Bonci A, Mercuri NB, Bernardi G. 1997. Effects of riluzole on rat cortical neurons: an in vitro electrophysiological study. Br J Pharmacol 120:225-230.
    • (1997) Br J Pharmacol , vol.120 , pp. 225-230
    • Siniscalchi, A.1    Bonci, A.2    Mercuri, N.B.3    Bernardi, G.4
  • 32
    • 0031733873 scopus 로고    scopus 로고
    • An electrophysiological analysis of the protective effects of felbamate, lamotrigine and lidocaine on the functional recovery from in vitro ischemia in rat neocortical slices
    • Siniscalchi A, Zona C, Guatteo E, Mercuri NB, Bernardi G. 1998. An electrophysiological analysis of the protective effects of felbamate, lamotrigine and lidocaine on the functional recovery from in vitro ischemia in rat neocortical slices. Synapse 30:371-379.
    • (1998) Synapse , vol.30 , pp. 371-379
    • Siniscalchi, A.1    Zona, C.2    Guatteo, E.3    Mercuri, N.B.4    Bernardi, G.5
  • 33
    • 0001664297 scopus 로고
    • Blockade of glutamatergic transmission and neuroprotection, the strange case of riluzole
    • Joelles G, Stutzmann JM, editors. London: Academic Press Ltd
    • Stutzmann JM, Doble A. 1994. Blockade of glutamatergic transmission and neuroprotection, the strange case of riluzole In: Joelles G, Stutzmann JM, editors. Neurodegenerative disease. London: Academic Press Ltd, p 205-214.
    • (1994) Neurodegenerative Disease , pp. 205-214
    • Stutzmann, J.M.1    Doble, A.2
  • 34
    • 0028024908 scopus 로고
    • Triggering and execution of neuronal death in brain ischaemia: Two phases of glutamate release by different mechanisms
    • Szatkowski M, Attwell D. 1994. Triggering and execution of neuronal death in brain ischaemia: two phases of glutamate release by different mechanisms. Trends Neurosci 17:359-365.
    • (1994) Trends Neurosci , vol.17 , pp. 359-365
    • Szatkowski, M.1    Attwell, D.2
  • 35
    • 0028979311 scopus 로고
    • Na+ channels as targets for neuroprotective drugs
    • Taylor CP, Meldrum BS. 1995. Na+ channels as targets for neuroprotective drugs. Trends Pharmacol Sci 16:309-316.
    • (1995) Trends Pharmacol Sci , vol.16 , pp. 309-316
    • Taylor, C.P.1    Meldrum, B.S.2
  • 36
    • 0028143404 scopus 로고
    • Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin lidocaine and phenytoin without blockade of action potentials
    • Weber ML, Taylor CP. 1994. Damage from oxygen and glucose deprivation in hippocampal slices is prevented by tetrodotoxin lidocaine and phenytoin without blockade of action potentials. Brain Res 664:167-177.
    • (1994) Brain Res , vol.664 , pp. 167-177
    • Weber, M.L.1    Taylor, C.P.2
  • 37
    • 0021272555 scopus 로고
    • An in vitro model of ischemia : Metabolic and electrical alterations in the hippocampal slice
    • Whittingham TS, Lust WD, Passoneau JV. 1984. An in vitro model of ischemia : metabolic and electrical alterations in the hippocampal slice. J Neurosci 4:793-802.
    • (1984) J Neurosci , vol.4 , pp. 793-802
    • Whittingham, T.S.1    Lust, W.D.2    Passoneau, J.V.3
  • 38
    • 0031901783 scopus 로고    scopus 로고
    • Riluzole interacts with voltage-activated sodium and potassium currents in cultured cortical neurons
    • Zona C, Siniscalchi A, Mercuri NB, Bernardi G. 1998. Riluzole interacts with voltage-activated sodium and potassium currents in cultured cortical neurons. Neuroscience 3:931-938.
    • (1998) Neuroscience , vol.3 , pp. 931-938
    • Zona, C.1    Siniscalchi, A.2    Mercuri, N.B.3    Bernardi, G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.