Neuronal regulation of glutamate transporter subtype expression in astrocytes

Journal of Neuroscience

Volumn 17, Issue 3, 1997, Pages 932-940

  Swanson, Raymond A ^a,b   Liu, Jialing ^a,b   Miller, Johann W ^a,b   Rothstein, Jeffrey D ^c   Farrell, Kevin ^a,b   Stein, Becky A ^a,b   Longuemare, Maria C ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

dibutyryl cAMP; dihydrokainate; GLAST; GLT 1; glutamate uptake; microglia; PDC; pyrrolidine 2,4 dicarboxylate; threo hydroxyaspartate

Indexed keywords

DIHYDROKAINIC ACID; GLUTAMIC ACID;

AMINO ACID TRANSPORT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL STRUCTURE; CONTROLLED STUDY; FOREBRAIN; GENE EXPRESSION REGULATION; IMMUNOCYTOCHEMISTRY; NERVE FIBER TRANSPORT; NONHUMAN; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM;

EID: 0031020015     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-03-00932.1997     Document Type: Article

References (12)

1. Arriza JL, Fairman WA, Wadiche JI, Murdoch GH, Kavanaugh MP, Amara SG (1994) Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J Neurosci 14:5559-5569.
2. Bjørås M, Gjesdal O, Erickson JD, Torp R, Levy LM, Ottersen OP, Degree M, Storm-Mathisen J, Seeberg E, Danbolt NC (1996) Cloning and expression of a neuronal rat brain glutamate transporter. Mol Brain Res 36:163-168.
3. Bristol LA, Rothstein JD (1996) Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex. Ann Neurol 39:676-679.
4. Cammer W (1990) Glutamine synthetase in the central nervous system is not confined to astrocytes. J Neuroimmunol 26:173-178.
5. Castellano D, Gonzalez B, Jensen MB, Pedersen EB, Finsen BR, Zimmer J (1991) A double staining technique for simultaneous demonstration of astrocytes and microglia in brain sections and astroglial cell cultures. J Histochem Cytochem 39:561-568.
6. Chaudhry FA, Lehre KP, Campagne MVL, Ottersen OP, Danbolt NC, Storm-Mathisen J (1995) Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry. Neuron 15:711-720.
7. +-dependent transport activity in synaptosomes, C6 glioma, and Xenopus oocytes expressing excitatory amino acid carrier 1 (EAAC1). Mol Pharmacol 49:465-473.
8. Pines G, Danbolt NC, Bj°räs M, Zhang Y, Bendahan A, Eide L, Koepsell H, Storm-Mathisen J, Seeberg E, Kanner BI (1992) Cloning and expression of a rat brain L-glutamate transporter. Nature 360:464-467.
9. Rothstein JD, Dykes-Hoberg M, Pardo CA, Bristol LA, Jin L, Kuncl RW, Kanai Y, Hediger M, Wang Y, Schielke JP, Welly DF (1996) Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16:675-686.
10. Rothstein JD, Martin L, Levey AI, Dykes-Hoberg M, Jin L, Wu D, Nash N, Kuncl RW (1994) Localization of neuronal and glial glutamate transporters. Neuron 13:713-725.
11. Vandenberg RJ, Arriza JL, Amara SG, Kavanaugh MP (1995) Constitutive ion fluxes and substrate binding domains of human glutamate transporters. J Biol Chem 270:17668-17671.
12. Zerangue N, Arriza JL, Amara SG, Kavanaugh MP (1995) Differential modulation of human glutamate transporter subtypes by arachidonic acid. J Biol Chem 270:6433-6435.