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Volumn 15, Issue 1, 2010, Pages 291-308

Immunoregulatory cells of the tumor microenvironment

Author keywords

Anergy; Cytotoxic T cells; Regulatory T cells; Review; Suppression; Tolerance; Tumor associated macrophages; Tumor microenvironment

Indexed keywords

AUTACOID;

EID: 77951215835     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3621     Document Type: Article
Times cited : (4)

References (191)
  • 2
    • 27644508279 scopus 로고    scopus 로고
    • Update on cancer vaccines
    • DOI 10.1097/01.cco.0000181406.60213.c7
    • F. K. Stevenson: Update on cancer vaccines. Curr Opin Oncol 17, 573-577 (2005). (Pubitemid 41566410)
    • (2005) Current Opinion in Oncology , vol.17 , Issue.6 , pp. 573-577
    • Stevenson, F.K.1
  • 4
    • 0034194329 scopus 로고    scopus 로고
    • Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade
    • A. A. Hurwitz, B. A. Foster, E. D. Kwon, T. Truong, E. M. Choi, N. M. Greenberg, M. B. Burg and J. P. Allison: Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade. Cancer Res 60, 2444-2448 (2000). (Pubitemid 30262435)
    • (2000) Cancer Research , vol.60 , Issue.9 , pp. 2444-2448
    • Hurwitz, A.A.1    Foster, B.A.2    Kwon, E.D.3    Truong, T.4    Choi, E.M.5    Greenberg, N.M.6    Burg, M.B.7    Allison, J.P.8
  • 5
    • 0033213599 scopus 로고    scopus 로고
    • + T cell- and IL-2-dependent mechanism
    • DOI 10.1016/S1074-7613(00)80123-5
    • P. Shrikant, A. Khoruts and M. F. Mescher: CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism. Immunity 11, 483-493 (1999). (Pubitemid 29504203)
    • (1999) Immunity , vol.11 , Issue.4 , pp. 483-493
    • Shrikant, P.1    Khoruts, A.2    Mescher, M.F.3
  • 6
    • 0033517152 scopus 로고    scopus 로고
    • Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony- stimulating factor (GM-CSF)-producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation
    • DOI 10.1084/jem.190.3.355
    • A. van Elsas, A. A. Hurwitz and J. P. Allison: Combination immunotherapy of B16 melanoma using anti-cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and granulocyte/macrophage colony-stimulating factor (GM-CSF)- producing vaccines induces rejection of subcutaneous and metastatic tumors accompanied by autoimmune depigmentation. J Exp Med 190, 355-366 (1999). (Pubitemid 29374833)
    • (1999) Journal of Experimental Medicine , vol.190 , Issue.3 , pp. 355-366
    • Van Elsas, A.1    Hurwitz, A.A.2    Allison, J.P.3
  • 8
    • 0029788299 scopus 로고    scopus 로고
    • Loss of a unique tumor antigen by cytotoxic T lymphocyte immunoselection from a 3-methylcholanthrene-induced mouse sarcoma reveals secondary unique and shared antigens
    • M. E. Dudley and D. C. Roopenian: Loss of a unique tumor antigen by cytotoxic T lymphocyte immunoselection from a 3-methylcholanthrene-induced mouse sarcoma reveals secondary unique and shared antigens. J Exp Med 184, 441-447 (1996). (Pubitemid 26324097)
    • (1996) Journal of Experimental Medicine , vol.184 , Issue.2 , pp. 441-447
    • Dudley, M.E.1    Roopenian, D.C.2
  • 9
    • 3042800613 scopus 로고    scopus 로고
    • Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment
    • O. F. Bathe, N. Dalyot-Herman and T. R. Malek: Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment. BMC Cancer 3, 21 (2003).
    • (2003) BMC Cancer , vol.3 , pp. 21
    • Bathe, O.F.1    Dalyot-Herman, N.2    Malek, T.R.3
  • 12
    • 68149166496 scopus 로고    scopus 로고
    • Spontaneous autoimmunity sufficiently potent to induce diabetes mellitus is insufficient to protect against insulinoma
    • In Press
    • K. A. Zwicker, C. Chatten, K. Gratton, D. Demetrick, P. Serra, P. Santamaria and O. F. Bathe: Spontaneous autoimmunity sufficiently potent to induce diabetes mellitus is insufficient to protect against insulinoma. J Immunol, In Press (2009).
    • (2009) J Immunol
    • Zwicker, K.A.1    Chatten, C.2    Gratton, K.3    Demetrick, D.4    Serra, P.5    Santamaria, P.6    Bathe, O.F.7
  • 13
    • 34247554229 scopus 로고    scopus 로고
    • + T cell response
    • J. M. den Haan, G. Kraal and M. J. Bevan: Cutting edge: Lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response. J Immunol 178, 5429-5433 (2007). (Pubitemid 46674336)
    • (2007) Journal of Immunology , vol.178 , Issue.9 , pp. 5429-5433
    • Den Haan, J.M.M.1    Kraal, G.2    Bevan, M.J.3
  • 14
    • 36549015611 scopus 로고    scopus 로고
    • Isolation, expansion, and characterization of human natural and adaptive regulatory T cells
    • DOI 10.1385/1-59745-395-1:83, Immunological Tolerance: Methods and Protocols
    • S. Gregori, R. Bacchetta, L. Passerini, M. K. Levings and M. G. Roncarolo: Isolation, expansion, and characterization of human natural and adaptive regulatory T cells. Methods Mol Biol 380, 83-105 (2007). (Pubitemid 350183324)
    • (2007) Methods in Molecular Biology , vol.380 , pp. 83-105
    • Gregori, S.1    Bacchetta, R.2    Passerini, L.3    Levings, M.K.4    Roncarolo, M.G.5
  • 16
    • 33747143361 scopus 로고    scopus 로고
    • From Vanilla to 28 Flavors: Multiple Varieties of T Regulatory Cells
    • DOI 10.1016/j.immuni.2006.08.003, PII S1074761306003578
    • E. M. Shevach: From vanilla to 28 flavors: multiple varieties of T regulatory cells. Immunity 25, 195-201 (2006). (Pubitemid 44224153)
    • (2006) Immunity , vol.25 , Issue.2 , pp. 195-201
    • Shevach, E.M.1
  • 17
    • 33947576560 scopus 로고    scopus 로고
    • Opinion: FOXP3 modifies the phenotypic and functional properties of regulatory T cells
    • DOI 10.1038/nri2061, PII NRI2061
    • D. J. Campbell and S. F. Ziegler: FOXP3 modifies the phenotypic and functional properties of regulatory T cells. Nat Rev Immunol 7, 305-310 (2007). (Pubitemid 46480960)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.4 , pp. 305-310
    • Campbell, D.J.1    Ziegler, S.F.2
  • 19
    • 0037385330 scopus 로고    scopus 로고
    • + regulatory T cells
    • DOI 10.1038/ni904
    • J. D. Fontenot, M. A. Gavin and A. Y. Rudensky: Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4, 330-336 (2003). (Pubitemid 36432314)
    • (2003) Nature Immunology , vol.4 , Issue.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 21
    • 0033136302 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • M. Itoh, T. Takahashi, N. Sakaguchi, Y. Kuniyasu, J. Shimizu, F. Otsuka and S. Sakaguchi: Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol 162, 5317-5326 (1999). (Pubitemid 29307138)
    • (1999) Journal of Immunology , vol.162 , Issue.9 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6    Sakaguchi, S.7
  • 22
    • 0033853625 scopus 로고    scopus 로고
    • + T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
    • Y. Kuniyasu, T. Takahashi, M. Itoh, J. Shimizu, G. Toda and S. Sakaguchi: Naturally anergic and suppressive CD25(+)CD4(+) T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation. Int Immunol 12, 1145-1155 (2000). (Pubitemid 30618021)
    • (2000) International Immunology , vol.12 , Issue.8 , pp. 1145-1155
    • Kuniyasu, Y.1    Takahashi, T.2    Itoh, M.3    Shimizu, J.4    Toda, G.5    Sakaguchi, S.6
  • 26
    • 0036195161 scopus 로고    scopus 로고
    • + Immunoregulatory T Cells: Gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • DOI 10.1016/S1074-7613(02)00280-7
    • R. S. McHugh, M. J. Whitters, C. A. Piccirillo, D. A. Young, E. M. Shevach, M. Collins and M. C. Byrne: CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid- induced TNF receptor. Immunity 16, 311- 323 (2002). (Pubitemid 34211969)
    • (2002) Immunity , vol.16 , Issue.2 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5    Collins, M.6    Byrne, M.C.7
  • 28
    • 0034679567 scopus 로고    scopus 로고
    • + regulatory cells that control intestinal inflammation
    • DOI 10.1084/jem.192.2.295
    • S. Read, V. Malmstrom and F. Powrie: Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J Exp Med 192, 295-302 (2000). (Pubitemid 30470312)
    • (2000) Journal of Experimental Medicine , vol.192 , Issue.2 , pp. 295-302
    • Read, S.1    Malmstrom, V.2    Powrie, F.3
  • 29
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • T. Takahashi, T. Tagami, S. Yamazaki, T. Uede, J. Shimizu, N. Sakaguchi, T. W. Mak and S. Sakaguchi: Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med 192, 303-310 (2000).
    • (2000) J Exp Med , vol.192 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6    Mak, T.W.7    Sakaguchi, S.8
  • 33
    • 15444374646 scopus 로고    scopus 로고
    • + regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
    • DOI 10.1084/jem.20041982
    • R. Setoguchi, S. Hori, T. Takahashi and S. Sakaguchi: Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization. J Exp Med 201, 723-735 (2005). (Pubitemid 40395118)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.5 , pp. 723-735
    • Setoguchi, R.1    Hori, S.2    Takahashi, T.3    Sakaguchi, S.4
  • 34
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • H. Jonuleit, E. Schmitt, G. Schuler, J. Knop and A. H. Enk: Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med 192, 1213- 1222 (2000).
    • (2000) J Exp Med , vol.192 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 35
    • 34547769253 scopus 로고    scopus 로고
    • All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
    • DOI 10.1084/jem.20070719
    • M. J. Benson, K. Pino-Lagos, M. Rosemblatt and R. J. Noelle: All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J Exp Med 204, 1765-1774 (2007). (Pubitemid 47236315)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.8 , pp. 1765-1774
    • Benson, M.J.1    Pino-Lagos, K.2    Rosemblatt, M.3    Noelle, R.J.4
  • 37
    • 0035421654 scopus 로고    scopus 로고
    • + immunoregulatory cells
    • C. A. Piccirillo and E. M. Shevach: Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells. J Immunol 167, 1137-1140 (2001). (Pubitemid 32703105)
    • (2001) Journal of Immunology , vol.167 , Issue.3 , pp. 1137-1140
    • Piccirillo, C.A.1    Shevach, E.M.2
  • 38
    • 0031821875 scopus 로고    scopus 로고
    • + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • DOI 10.1084/jem.188.2.287
    • A. M. Thornton and E. M. Shevach: CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 188, 287-296 (1998). (Pubitemid 28357757)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.2 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 39
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
    • J. Shimizu, S. Yamazaki and S. Sakaguchi: Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163, 5211-5218 (1999).
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 40
    • 0037131969 scopus 로고    scopus 로고
    • + T suppressor cell clones produce transforming growth factor β, but not interleukin 10, and are distinct from type 1 T regulatory cells
    • DOI 10.1084/jem.20021139
    • M. K. Levings, R. Sangregorio, C. Sartirana, A. L. Moschin, M. Battaglia, P. C. Orban and M. G. Roncarolo: Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. J Exp Med 196, 1335-1346 (2002). (Pubitemid 35375552)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.10 , pp. 1335-1346
    • Levings, M.K.1    Sangregorio, R.2    Sartirana, C.3    Moschin, A.L.4    Battaglia, M.5    Orban, P.C.6    Roncarolo, M.-G.7
  • 41
    • 15444377017 scopus 로고    scopus 로고
    • + cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
    • DOI 10.1084/jem.20041684
    • P. Yu, Y. Lee, W. Liu, T. Krausz, A. Chong, H. Schreiber and Y. X. Fu: Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J Exp Med 201, 779-791 (2005). (Pubitemid 40395122)
    • (2005) Journal of Experimental Medicine , vol.201 , Issue.5 , pp. 779-791
    • Yu, P.1    Lee, Y.2    Liu, W.3    Krausz, T.4    Chong, A.5    Schreiber, H.6    Fu, Y.-X.7
  • 42
    • 16844361893 scopus 로고    scopus 로고
    • Altered immunity accompanies disease progression in a mouse model of prostate dysplasia
    • DOI 10.1158/0008-5472.CAN-04-3271
    • A. H. Tien, L. Xu and C. D. Helgason: Altered immunity accompanies disease progression in a mouse model of prostate dysplasia. Cancer Res 65, 2947-2955 (2005). (Pubitemid 40490100)
    • (2005) Cancer Research , vol.65 , Issue.7 , pp. 2947-2955
    • Tien, A.H.1    Xu, L.2    Helgason, C.D.3
  • 43
    • 0041386189 scopus 로고    scopus 로고
    • + regulatory T cells in patients with gastrointestinal malignancies: Possible involvement of regulatory T cells in disease progression
    • DOI 10.1002/cncr.11618
    • T. Sasada, M. Kimura, Y. Yoshida, M. Kanai and A. Takabayashi: CD4+CD25+ regulatory T cells in patients with gastrointestinal malignancies: possible involvement of regulatory T cells in disease progression. Cancer 98, 1089- 1099 (2003). (Pubitemid 37022112)
    • (2003) Cancer , vol.98 , Issue.5 , pp. 1089-1099
    • Sasada, T.1    Kimura, M.2    Yoshida, Y.3    Kanai, M.4    Takabayashi, A.5
  • 44
    • 0141891466 scopus 로고    scopus 로고
    • Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers
    • F. Ichihara, K. Kono, A. Takahashi, H. Kawaida, H. Sugai and H. Fujii: Increased populations of regulatory T cells in peripheral blood and tumor-infiltrating lymphocytes in patients with gastric and esophageal cancers. Clin Cancer Res 9, 4404- 4408 (2003). (Pubitemid 37248397)
    • (2003) Clinical Cancer Research , vol.9 , Issue.12 , pp. 4404-4408
    • Ichihara, F.1    Kono, K.2    Takahashi, A.3    Kawaida, H.4    Sugai, H.5    Fujii, H.6
  • 46
    • 39149128285 scopus 로고    scopus 로고
    • Regulatory T cells: What role do they play in antitumor immunity in patients with head and neck cancer?
    • DOI 10.1002/hed.20739
    • O. Alhamarneh, S. M. Amarnath, N. D. Stafford and J. Greenman: Regulatory T cells: what role do they play in antitumor immunity in patients with head and neck cancer? Head Neck 30, 251-261 (2008). (Pubitemid 351251710)
    • (2008) Head and Neck , vol.30 , Issue.2 , pp. 251-261
    • Alhamarneh, O.1    Amarnath, S.M.P.2    Stafford, N.D.3    Greenman, J.4
  • 47
    • 0035874949 scopus 로고    scopus 로고
    • + T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
    • E. Y. Woo, C. S. Chu, T. J. Goletz, K. Schlienger, H. Yeh, G. Coukos, S. C. Rubin, L. R. Kaiser and C. H. June: Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res 61, 4766-4772 (2001). (Pubitemid 32691889)
    • (2001) Cancer Research , vol.61 , Issue.12 , pp. 4766-4772
    • Woo, E.Y.1    Chu, C.S.2    Goletz, T.J.3    Schlienger, K.4    Yeh, H.5    Coukos, G.6    Rubin, S.C.7    Kaiser, L.R.8    June, C.H.9
  • 48
    • 0036569127 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
    • E. Y. Woo, H. Yeh, C. S. Chu, K. Schlienger, R. G. Carroll, J. L. Riley, L. R. Kaiser and C. H. June: Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J Immunol 168, 4272-4276 (2002). (Pubitemid 34441324)
    • (2002) Journal of Immunology , vol.168 , Issue.9 , pp. 4272-4276
    • Woo, E.Y.1    Yeh, H.2    Chu, C.S.3    Schlienger, K.4    Carroll, R.G.5    Riley, J.L.6    Kaiser, L.R.7    June, C.H.8
  • 51
    • 33744457276 scopus 로고    scopus 로고
    • high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers
    • DOI 10.1007/s00262-005-0092-8
    • K. Kono, H. Kawaida, A. Takahashi, H. Sugai, K. Mimura, N. Miyagawa, H. Omata and H. Fujii: CD4(+)CD25high regulatory T cells increase with tumor stage in patients with gastric and esophageal cancers. Cancer Immunol Immunother 55, 1064-1071 (2006). (Pubitemid 43800721)
    • (2006) Cancer Immunology, Immunotherapy , vol.55 , Issue.9 , pp. 1064-1071
    • Kono, K.1    Kawaida, H.2    Takahashi, A.3    Sugai, H.4    Mimura, K.5    Miyagawa, N.6    Omata, H.7    Fujii, H.8
  • 53
    • 0038792101 scopus 로고    scopus 로고
    • + regulatory T cells by targeting of antigens to immature dendritic cells
    • K. Mahnke, Y. Qian, J. Knop and A. H. Enk: Induction of CD4+/CD25+ regulatory T cells by targeting of antigens to immature dendritic cells. Blood 101, 4862-4869 (2003). (Pubitemid 36857748)
    • (2003) Blood , vol.101 , Issue.12 , pp. 4862-4869
    • Mahnke, K.1    Qian, Y.2    Knop, J.3    Enk, A.H.4
  • 54
    • 0036715411 scopus 로고    scopus 로고
    • Immature, semi-mature and fully mature dendritic cells: Which signals induce tolerance or immunity?
    • DOI 10.1016/S1471-4906(02)02281-0, PII S1471490602022810
    • M. B. Lutz and G. Schuler: Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity? Trends Immunol 23, 445-449 (2002). (Pubitemid 35015188)
    • (2002) Trends in Immunology , vol.23 , Issue.9 , pp. 445-449
    • Lutz, M.B.1    Schuler, G.2
  • 57
    • 0036931115 scopus 로고    scopus 로고
    • Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets
    • DOI 10.1016/S0198-8859(02)00754-1, PII S0198885902007541
    • M. Kuwana: Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets. Hum Immunol 63, 1156-1163 (2002). (Pubitemid 36025990)
    • (2002) Human Immunology , vol.63 , Issue.12 , pp. 1156-1163
    • Kuwana, M.1
  • 59
    • 0034077559 scopus 로고    scopus 로고
    • + regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells
    • DOI 10.1002/1521-4141(200006)30:6<1538::AID-IMMU1538>3.0.CO;2-X
    • L. Cederbom, H. Hall and F. Ivars: CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells. Eur J Immunol 30, 1538-1543 (2000). (Pubitemid 30342794)
    • (2000) European Journal of Immunology , vol.30 , Issue.6 , pp. 1538-1543
    • Cederbom, L.1    Hall, H.2    Ivars, F.3
  • 60
    • 1842581857 scopus 로고    scopus 로고
    • + T Cells Restrain the Maturation and Antigen-Presenting Function of Dendritic Cells
    • N. Misra, J. Bayry, S. Lacroix-Desmazes, M. D. Kazatchkine and S. V. Kaveri: Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigenpresenting function of dendritic cells. J Immunol 172, 4676-4680 (2004). (Pubitemid 38456386)
    • (2004) Journal of Immunology , vol.172 , Issue.8 , pp. 4676-4680
    • Misra, N.1    Bayry, J.2    Lacroix-Desmazes, S.3    Kazatchkine, M.D.4    Kaveri, S.V.5
  • 61
    • 25444497719 scopus 로고    scopus 로고
    • + regulatory T cells
    • H. W. Lim, P. Hillsamer, A. H. Banham and C. H. Kim: Cutting edge: direct suppression of B cells by CD4+ CD25+ regulatory T cells. J Immunol 175, 4180-4183 (2005). (Pubitemid 41361949)
    • (2005) Journal of Immunology , vol.175 , Issue.7 , pp. 4180-4183
    • Lim, H.W.1    Hillsamer, P.2    Banham, A.H.3    Kim, C.H.4
  • 62
    • 33646007957 scopus 로고    scopus 로고
    • Human CD4+CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation
    • R. Houot, I. Perrot, E. Garcia, I. Durand and S. Lebecque: Human CD4+CD25high regulatory T cells modulate myeloid but not plasmacytoid dendritic cells activation. J Immunol 176, 5293-5298 (2006).
    • (2006) J Immunol , vol.176 , pp. 5293-5298
    • Houot, R.1    Perrot, I.2    Garcia, E.3    Durand, I.4    Lebecque, S.5
  • 63
    • 33646487145 scopus 로고    scopus 로고
    • Modulation of dendritic cell function by naive and regulatory CD4+ T cells
    • M. Veldhoen, H. Moncrieffe, R. J. Hocking, C. J. Atkins and B. Stockinger: Modulation of dendritic cell function by naive and regulatory CD4+ T cells. J Immunol 176, 6202-6210 (2006).
    • (2006) J Immunol , vol.176 , pp. 6202-6210
    • Veldhoen, M.1    Moncrieffe, H.2    Hocking, R.J.3    Atkins, C.J.4    Stockinger, B.5
  • 65
    • 0033571785 scopus 로고    scopus 로고
    • In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas
    • D. Bell, P. Chomarat, D. Broyles, G. Netto, G. M. Harb, S. Lebecque, J. Valladeau, J. Davoust, K. A. Palucka and J. Banchereau: In breast carcinoma tissue, immature dendritic cells reside within the tumor, whereas mature dendritic cells are located in peritumoral areas. J Exp Med 190, 1417-1426 (1999).
    • (1999) J Exp Med , vol.190 , pp. 1417-1426
    • Bell, D.1    Chomarat, P.2    Broyles, D.3    Netto, G.4    Harb, G.M.5    Lebecque, S.6    Valladeau, J.7    Davoust, J.8    Palucka, K.A.9    Banchereau, J.10
  • 68
    • 33845360673 scopus 로고    scopus 로고
    • Characterisation of dendritic cell subsets in lung cancer micro-environments
    • DOI 10.1183/09031936.06.00114205
    • A. Bergeron, F. El Hage, M. Kambouchner, D. Lecossier and A. Tazi: Characterisation of dendritic cell subsets in lung cancer micro-environments. Eur Respir J 28, 1170-1177 (2006). (Pubitemid 44883852)
    • (2006) European Respiratory Journal , vol.28 , Issue.6 , pp. 1170-1177
    • Bergeron, A.1    El Hage, F.2    Kambouchner, M.3    Lecossier, D.4    Tazi, A.5
  • 69
    • 0027727917 scopus 로고
    • S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival
    • N. A. Zeid and H. K. Muller: S100 positive dendritic cells in human lung tumors associated with cell differentiation and enhanced survival. Pathology 25, 338- 343 (1993). (Pubitemid 24238309)
    • (1993) Pathology , vol.25 , Issue.4 , pp. 338-343
    • Zeid, N.A.1    Muller, H.K.2
  • 70
    • 34347393898 scopus 로고    scopus 로고
    • + mature dendritic cells in combination with activated T lymphocytes infiltrating primary cutaneous melanoma is a strong independent prognostic factor
    • DOI 10.1007/s00262-007-0286-3
    • A. Ladanyi, J. Kiss, B. Somlai, K. Gilde, Z. Fejos, A. Mohos, I. Gaudi and J. Timar: Density of DC-LAMP(+) mature dendritic cells in combination with activated T lymphocytes infiltrating primary cutaneous melanoma is a strong independent prognostic factor. Cancer Immunol Immunother 56, 1459-1469 (2007). (Pubitemid 47024707)
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.9 , pp. 1459-1469
    • Ladanyi, A.1    Kiss, J.2    Somlai, B.3    Gilde, K.4    Fejos, Z.5    Mohos, A.6    Gaudi, I.7    Timar, J.8
  • 71
    • 0029937941 scopus 로고    scopus 로고
    • Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation
    • P. Chaux, M. Moutet, J. Faivre, F. Martin and M. Martin: Inflammatory cells infiltrating human colorectal carcinomas express HLA class II but not B7-1 and B7-2 costimulatory molecules of the T-cell activation. Lab Invest 74, 975-983 (1996). (Pubitemid 26152665)
    • (1996) Laboratory Investigation , vol.74 , Issue.5 , pp. 975-983
    • Chaux, P.1    Moutet, M.2    Faivre, J.3    Martin, F.4    Martin, M.5
  • 72
    • 15244349785 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells in immunity
    • DOI 10.1038/ni1141
    • M. Colonna, G. Trinchieri and Y. J. Liu: Plasmacytoid dendritic cells in immunity. Nat Immunol 5, 1219-1226 (2004). (Pubitemid 41057736)
    • (2004) Nature Immunology , vol.5 , Issue.12 , pp. 1219-1226
    • Colonna, M.1    Trinchieri, G.2    Liu, Y.-J.3
  • 75
    • 0038545821 scopus 로고    scopus 로고
    • Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas
    • DOI 10.1002/path.1344
    • W. Vermi, R. Bonecchi, F. Facchetti, D. Bianchi, S. Sozzani, S. Festa, A. Berenzi, M. Cella and M. Colonna: Recruitment of immature plasmacytoid dendritic cells (plasmacytoid monocytes) and myeloid dendritic cells in primary cutaneous melanomas. J Pathol 200, 255-268 (2003). (Pubitemid 36748035)
    • (2003) Journal of Pathology , vol.200 , Issue.2 , pp. 255-268
    • Vermi, W.1    Bonecchi, R.2    Facchetti, F.3    Bianchi, D.4    Sozzani, S.5    Festa, S.6    Berenzi, A.7    Cella, M.8    Colonna, M.9
  • 77
    • 41149132390 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
    • DOI 10.1111/j.1600-065X.2008.00610.x
    • J. B. Katz, A. J. Muller and G. C. Prendergast: Indoleamine 2, 3-dioxygenase in T-cell tolerance and tumoral immune escape. Immunol Rev 222, 206-221 (2008). (Pubitemid 351430372)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 206-221
    • Katz, J.B.1    Muller, A.J.2    Prendergast, G.C.3
  • 78
    • 0036201320 scopus 로고    scopus 로고
    • Correlation of vascular endothelial growth factor-C expression with tumor-infiltrating dendritic cells in gastric cancer
    • DOI 10.1159/000048257
    • A. Takahashi, K. Kono, J. Itakura, H. Amemiya, T. R. Feng, H. Iizuka, H. Fujii and Y. Matsumoto: Correlation of vascular endothelial growth factor-C expression with tumor-infiltrating dendritic cells in gastric cancer. Oncology 62, 121-127 (2002). (Pubitemid 34253081)
    • (2002) Oncology , vol.62 , Issue.2 , pp. 121-127
    • Takahashi, A.1    Kono, K.2    Itakura, J.3    Amemiya, H.4    Feng Tang, R.5    Iizuka, H.6    Fujii, H.7    Matsumoto, Y.8
  • 79
    • 0024548430 scopus 로고
    • S-100 protein-positive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis
    • DOI 10.1002/1097-0142(19890201)63:3<496::AID-CNCR2820630318>3.0. CO;2-K
    • K. Ambe, M. Mori and M. Enjoji: S-100 proteinpositive dendritic cells in colorectal adenocarcinomas. Distribution and relation to the clinical prognosis. Cancer 63, 496-503 (1989). (Pubitemid 19038466)
    • (1989) Cancer , vol.63 , Issue.3 , pp. 496-503
    • Ambe, K.1    Mori, M.2    Enjoji, M.3
  • 80
    • 33645991795 scopus 로고    scopus 로고
    • Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
    • A. Sica, T. Schioppa, A. Mantovani and P. Allavena: Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy. Eur J Cancer 42, 717-727 (2006).
    • (2006) Eur J Cancer , vol.42 , pp. 717-727
    • Sica, A.1    Schioppa, T.2    Mantovani, A.3    Allavena, P.4
  • 81
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: Role in tumour progression
    • DOI 10.1016/j.ejca.2004.03.016, PII S0959804904002850
    • A. Mantovani, P. Allavena and A. Sica: Tumourassociated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur J Cancer 40, 1660-1667 (2004). (Pubitemid 38902900)
    • (2004) European Journal of Cancer , vol.40 , Issue.11 , pp. 1660-1667
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 83
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
    • A. Mantovani, A. Sica, S. Sozzani, P. Allavena, A. Vecchi and M. Locati: The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25, 677-686 (2004). (Pubitemid 39457982)
    • (2004) Trends in Immunology , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 84
    • 0035901090 scopus 로고    scopus 로고
    • Inflammation and cancer: Back to Virchow?
    • DOI 10.1016/S0140-6736(00)04046-0
    • F. Balkwill and A. Mantovani: Inflammation and cancer: back to Virchow? Lancet 357, 539-545 (2001). (Pubitemid 32173595)
    • (2001) Lancet , vol.357 , Issue.9255 , pp. 539-545
    • Balkwill, F.1    Mantovani, A.2
  • 85
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • DOI 10.1038/nri978
    • S. Gordon: Alternative activation of macrophages. Nat Rev Immunol 3, 23-35 (2003). (Pubitemid 37328697)
    • (2003) Nature Reviews Immunology , vol.3 , Issue.1 , pp. 23-35
    • Gordon, S.1
  • 86
    • 0036658739 scopus 로고    scopus 로고
    • A novel phenotype for an activated macrophage: The type 2 activated macrophage
    • C. F. Anderson and D. M. Mosser: A novel phenotype for an activated macrophage: the type 2 activated macrophage. J Leukoc Biol 72, 101-106 (2002).
    • (2002) J Leukoc Biol , vol.72 , pp. 101-106
    • Anderson, C.F.1    Mosser, D.M.2
  • 87
    • 0033082935 scopus 로고    scopus 로고
    • Other functions, other genes: Alternative activation of antigen- presenting cells
    • S. Goerdt and C. E. Orfanos: Other functions, other genes: alternative activation of antigen-presenting cells. Immunity 10, 137-142 (1999). (Pubitemid 29115619)
    • (1999) Immunity , vol.10 , Issue.2 , pp. 137-142
    • Goerdt, S.1    Orfanos, C.E.2
  • 88
    • 26644452073 scopus 로고    scopus 로고
    • Macrophage polarization comes of age
    • DOI 10.1016/j.immuni.2005.10.001, PII S1074761305003134
    • A. Mantovani, A. Sica and M. Locati: Macrophage polarization comes of age. Immunity 23, 344-346 (2005). (Pubitemid 41443435)
    • (2005) Immunity , vol.23 , Issue.4 , pp. 344-346
    • Mantovani, A.1    Sica, A.2    Locati, M.3
  • 91
    • 0033214545 scopus 로고    scopus 로고
    • Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells
    • M. Munder, K. Eichmann, J. M. Moran, F. Centeno, G. Soler and M. Modolell: Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells. J Immunol 163, 3771-3777 (1999). (Pubitemid 29450901)
    • (1999) Journal of Immunology , vol.163 , Issue.7 , pp. 3771-3777
    • Munder, M.1    Eichmann, K.2    Moran, J.M.3    Centeno, F.4    Soler, G.5    Modolell, M.6
  • 93
    • 0037080191 scopus 로고    scopus 로고
    • Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages
    • A. C. Morrison and P. H. Correll: Activation of the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase by macrophage-stimulating protein results in the induction of arginase activity in murine peritoneal macrophages. J Immunol 168, 853-860 (2002). (Pubitemid 34049588)
    • (2002) Journal of Immunology , vol.168 , Issue.2 , pp. 853-860
    • Morrison, A.C.1    Correll, P.H.2
  • 94
    • 0642272298 scopus 로고    scopus 로고
    • 1 on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12: A potential role during arteriogenesis
    • DOI 10.1096/fj.03-0071fje
    • M. M. Jost, E. Ninci, B. Meder, C. Kempf, N. Van Royen, J. Hua, B. Berger, I. Hoefer, M. Modolell and I. Buschmann: Divergent effects of GM-CSF and TGFbeta1 on bone marrow-derived macrophage arginase-1 activity, MCP-1 expression, and matrix metalloproteinase-12: a potential role during arteriogenesis. FASEB J 17, 2281- 2283 (2003). (Pubitemid 39561466)
    • (2003) FASEB Journal , vol.17 , Issue.15 , pp. 2281-2283
    • Jost, M.M.1    Ninci, E.2    Meder, B.3    Kempf, C.4    Van Royen, N.5    Hua, T.6    Berger, B.7    Hoefer, I.8    Modolell, M.9    Buschmann, I.10
  • 97
    • 33947515407 scopus 로고    scopus 로고
    • Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice
    • DOI 10.2353/ajpath.2007.060566
    • E. F. Redente, D. J. Orlicky, R. J. Bouchard and A. M. Malkinson: Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice. Am J Pathol 170, 693-708 (2007). (Pubitemid 47339405)
    • (2007) American Journal of Pathology , vol.170 , Issue.2 , pp. 693-708
    • Redente, E.F.1    Orlicky, D.J.2    Bouchard, R.J.3    Malkinson, A.M.4
  • 98
    • 34548697727 scopus 로고    scopus 로고
    • Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors
    • DOI 10.1016/j.humpath.2007.02.018, PII S004681770700127X
    • D. Massi, C. Marconi, A. Franchi, F. Bianchini, M. Paglierani, S. Ketabchi, C. Miracco, M. Santucci and L. Calorini: Arginine metabolism in tumor-associated macrophages in cutaneous malignant melanoma: evidence from human and experimental tumors. Hum Pathol 38, 1516-1525 (2007). (Pubitemid 47418963)
    • (2007) Human Pathology , vol.38 , Issue.10 , pp. 1516-1525
    • Massi, D.1    Marconi, C.2    Franchi, A.3    Bianchini, F.4    Paglierani, M.5    Ketabchi, S.6    Miracco, C.7    Santucci, M.8    Calorini, L.9
  • 99
    • 33745938947 scopus 로고    scopus 로고
    • Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions
    • DOI 10.1182/blood-2005-04-1485
    • G. H. Ghassabeh, P. De Baetselier, L. Brys, W. Noel, J. A. Van Ginderachter, S. Meerschaut, A. Beschin, F. Brombacher and G. Raes: Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood 108, 575-583 (2006). (Pubitemid 44061358)
    • (2006) Blood , vol.108 , Issue.2 , pp. 575-583
    • Ghassabeh, G.H.1    De Baetselier, P.2    Brys, L.3    Noel, W.4    Van Ginderachter, J.A.5    Meerschaut, S.6    Beschin, A.7    Brombacher, F.8    Raes, G.9
  • 101
    • 0034650833 scopus 로고    scopus 로고
    • Autocrine production of IL-10 mediates defective IL-12 production and NF-κB activation in tumor-associated macrophages
    • A. Sica, A. Saccani, B. Bottazzi, N. Polentarutti, A. Vecchi, J. van Damme and A. Mantovani: Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages. J Immunol 164, 762-767 (2000). (Pubitemid 30043699)
    • (2000) Journal of Immunology , vol.164 , Issue.2 , pp. 762-767
    • Sica, A.1    Saccani, A.2    Bottazzi, B.3    Polentarutti, N.4    Vecchi, A.5    Van Damme, J.6    Mantovani, A.7
  • 102
    • 0029913684 scopus 로고    scopus 로고
    • The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene
    • M. R. Dinapoli, C. L. Calderon and D. M. Lopez: The altered tumoricidal capacity of macrophages isolated from tumor-bearing mice is related to reduce expression of the inducible nitric oxide synthase gene. J Exp Med 183, 1323- 1329 (1996).
    • (1996) J Exp Med , vol.183 , pp. 1323-1329
    • Dinapoli, M.R.1    Calderon, C.L.2    Lopez, D.M.3
  • 103
    • 0035476888 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-2 and inducible nitric oxide synthase in human ovarian tumors and tumor-associated macrophages
    • A. H. Klimp, H. Hollema, C. Kempinga, A. G. van der Zee, E. G. de Vries and T. Daemen: Expression of cyclooxygenase-2 and inducible nitric oxide synthase in human ovarian tumors and tumor-associated macrophages. Cancer Res 61, 7305-7309 (2001). (Pubitemid 32946529)
    • (2001) Cancer Research , vol.61 , Issue.19 , pp. 7305-7309
    • Klimp, A.H.1    Hollema, H.2    Kempinga, C.3    Van Der Zee, A.G.J.4    De Vries, E.G.E.5    Daemen, T.6
  • 104
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
    • A. Mantovani, S. Sozzani, M. Locati, P. Allavena and A. Sica: Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23, 549-555 (2002). (Pubitemid 35223554)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 105
    • 24744454660 scopus 로고    scopus 로고
    • Macrophage infiltration and its prognostic implications in breast cancer: The relationship with VEGF expression and microvessel density
    • S. Tsutsui, K. Yasuda, K. Suzuki, K. Tahara, H. Higashi and S. Era: Macrophage infiltration and its prognostic implications in breast cancer: the relationship with VEGF expression and microvessel density. Oncol Rep 14, 425-431 (2005).
    • (2005) Oncol Rep , vol.14 , pp. 425-431
    • Tsutsui, S.1    Yasuda, K.2    Suzuki, K.3    Tahara, K.4    Higashi, H.5    Era, S.6
  • 106
    • 43549124115 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma
    • C. Y. Chai, W. T. Chen, W. C. Hung, W. Y. Kang, Y. C. Huang, Y. C. Su and C. H. Yang: Hypoxia-inducible factor-1alpha expression correlates with focal macrophage infiltration, angiogenesis and unfavourable prognosis in urothelial carcinoma. J Clin Pathol 61, 658-664 (2008).
    • (2008) J Clin Pathol , vol.61 , pp. 658-664
    • Chai, C.Y.1    Chen, W.T.2    Hung, W.C.3    Kang, W.Y.4    Huang, Y.C.5    Su, Y.C.6    Yang, C.H.7
  • 107
    • 0029816609 scopus 로고    scopus 로고
    • Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma
    • R. D. Leek, C. E. Lewis, R. Whitehouse, M. Greenall, J. Clarke and A. L. Harris: Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma. Cancer Res 56, 4625-4629 (1996). (Pubitemid 26338061)
    • (1996) Cancer Research , vol.56 , Issue.20 , pp. 4625-4629
    • Leek, R.D.1    Lewis, C.E.2    Whitehouse, R.3    Greenall, M.4    Clarke, J.5    Harris, A.L.6
  • 108
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2α (HIF-2α) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • R. D. Leek, K. L. Talks, F. Pezzella, H. Turley, L. Campo, N. S. Brown, R. Bicknell, M. Taylor, K. C. Gatter and A. L. Harris: Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer. Cancer Res 62, 1326-1329 (2002). (Pubitemid 34407787)
    • (2002) Cancer Research , vol.62 , Issue.5 , pp. 1326-1329
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3    Turley, H.4    Campo, L.5    Brown, N.S.6    Bicknell, R.7    Taylor, M.8    Gatter, K.C.9    Harris, A.L.10
  • 109
    • 27744603002 scopus 로고    scopus 로고
    • Hypoxia regulates macrophage functions in inflammation
    • C. Murdoch, M. Muthana and C. E. Lewis: Hypoxia regulates macrophage functions in inflammation. J Immunol 175, 6257-6263 (2005). (Pubitemid 41598863)
    • (2005) Journal of Immunology , vol.175 , Issue.10 , pp. 6257-6263
    • Murdoch, C.1    Muthana, M.2    Lewis, C.E.3
  • 110
    • 39849102836 scopus 로고    scopus 로고
    • HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion
    • DOI 10.1016/j.ccr.2008.01.034, PII S153561080800041X
    • R. Du, K. V. Lu, C. Petritsch, P. Liu, R. Ganss, E. Passegue, H. Song, S. Vandenberg, R. S. Johnson, Z. Werb and G. Bergers: HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer Cell 13, 206-220 (2008). (Pubitemid 351318372)
    • (2008) Cancer Cell , vol.13 , Issue.3 , pp. 206-220
    • Du, R.1    Lu, K.V.2    Petritsch, C.3    Liu, P.4    Ganss, R.5    Passegue, E.6    Song, H.7    VandenBerg, S.8    Johnson, R.S.9    Werb, Z.10    Bergers, G.11
  • 111
    • 42449100017 scopus 로고    scopus 로고
    • Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells
    • C. Marconi, F. Bianchini, A. Mannini, G. Mugnai, S. Ruggieri and L. Calorini: Tumoral and macrophage uPAR and MMP-9 contribute to the invasiveness of B16 murine melanoma cells. Clin Exp Metastasis 25, 225-231 (2008).
    • (2008) Clin Exp Metastasis , vol.25 , pp. 225-231
    • Marconi, C.1    Bianchini, F.2    Mannini, A.3    Mugnai, G.4    Ruggieri, S.5    Calorini, L.6
  • 113
    • 42249115328 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma
    • DOI 10.1158/1535-7163.MCT-07-0579
    • N. R. Miselis, Z. J. Wu, N. Van Rooijen and A. B. Kane: Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma. Mol Cancer Ther 7, 788-799 (2008). (Pubitemid 351551032)
    • (2008) Molecular Cancer Therapeutics , vol.7 , Issue.4 , pp. 788-799
    • Miselis, N.R.1    Wu, Z.J.2    Van Rooijen, N.3    Kane, A.B.4
  • 114
    • 33845524204 scopus 로고    scopus 로고
    • Role of tumor-associated macrophages in tumor progression and invasion
    • DOI 10.1007/s10555-006-9001-7, Special Issue on Pro-inflammatory Cytokines in Cancer
    • A. Mantovani, T. Schioppa, C. Porta, P. Allavena and A. Sica: Role of tumor-associated macrophages in tumor progression and invasion. Cancer Metastasis Rev 25, 315-322 (2006). (Pubitemid 44922352)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.3 , pp. 315-322
    • Mantovani, A.1    Schioppa, T.2    Porta, C.3    Allavena, P.4    Sica, A.5
  • 117
    • 45749137283 scopus 로고    scopus 로고
    • High expression of macrophage colonystimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma
    • X. D. Zhu, J. B. Zhang, P. Y. Zhuang, H. G. Zhu, W. Zhang, Y. Q. Xiong, W. Z. Wu, L. Wang, Z. Y. Tang and H. C. Sun: High expression of macrophage colonystimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J Clin Oncol 26, 2707-2716 (2008).
    • (2008) J Clin Oncol , vol.26 , pp. 2707-2716
    • Zhu, X.D.1    Zhang, J.B.2    Zhuang, P.Y.3    Zhu, H.G.4    Zhang, W.5    Xiong, Y.Q.6    Wu, W.Z.7    Wang, L.8    Tang, Z.Y.9    Sun, H.C.10
  • 118
    • 33745078300 scopus 로고    scopus 로고
    • Tumour-associated macrophages are related to progression in patients with metastatic melanoma following interleukin-2 based immunotherapy
    • DOI 10.1080/02841860500471798, PII U818123338112651
    • B. D. Hansen, H. Schmidt, M. H. von der, P. Sjoegren, R. Agger and M. Hokland: Tumour-associated macrophages are related to progression in patients with metastatic melanoma following interleukin-2 based immunotherapy. Acta Oncol 45, 400-405 (2006). (Pubitemid 43884607)
    • (2006) Acta Oncologica , vol.45 , Issue.4 , pp. 400-405
    • Hansen, B.D.1    Schmidt, H.2    Von Der Maase, H.3    Sjoegren, P.4    Agger, R.5    Hokland, M.6
  • 119
    • 41149119143 scopus 로고    scopus 로고
    • Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells
    • DOI 10.1111/j.1600-065X.2008.00602.x
    • I. Marigo, L. Dolcetti, P. Serafini, P. Zanovello and V. Bronte: Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells. Immunol Rev 222, 162-179 (2008). (Pubitemid 351430364)
    • (2008) Immunological Reviews , vol.222 , Issue.1 , pp. 162-179
    • Marigo, I.1    Dolcetti, L.2    Serafini, P.3    Zanovello, P.4    Bronte, V.5
  • 121
    • 0034551670 scopus 로고    scopus 로고
    • Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells
    • V. Bronte, E. Apolloni, A. Cabrelle, R. Ronca, P. Serafini, P. Zamboni, N. P. Restifo and P. Zanovello: Identification of a CD11b(+)/Gr-1(+)/CD31(+) myeloid progenitor capable of activating or suppressing CD8(+) T cells. Blood 96, 3838-3846 (2000).
    • (2000) Blood , vol.96 , pp. 3838-3846
    • Bronte, V.1    Apolloni, E.2    Cabrelle, A.3    Ronca, R.4    Serafini, P.5    Zamboni, P.6    Restifo, N.P.7    Zanovello, P.8
  • 122
    • 0028942668 scopus 로고
    • Mechanisms of immune suppression in patients with head and neck cancer: Presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocytemacrophage colony-stimulating factor
    • A. S. Pak, M. A. Wright, J. P. Matthews, S. L. Collins, G. J. Petruzzelli and M. R. Young: Mechanisms of immune suppression in patients with head and neck cancer: presence of CD34(+) cells which suppress immune functions within cancers that secrete granulocytemacrophage colony-stimulating factor. Clin Cancer Res 1, 95-103 (1995).
    • (1995) Clin Cancer Res , vol.1 , pp. 95-103
    • Pak, A.S.1    Wright, M.A.2    Matthews, J.P.3    Collins, S.L.4    Petruzzelli, G.J.5    Young, M.R.6
  • 128
    • 1642536454 scopus 로고    scopus 로고
    • + T Cell Response by Immature Myeloid Cells in Cancer Is Mediated by Reactive Oxygen Species
    • S. Kusmartsev, Y. Nefedova, D. Yoder and D. I. Gabrilovich: Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species. J Immunol 172, 989-999 (2004). (Pubitemid 38113758)
    • (2004) Journal of Immunology , vol.172 , Issue.2 , pp. 989-999
    • Kusmartsev, S.1    Nefedova, Y.2    Yoder, D.3    Gabrilovich, D.I.4
  • 130
    • 29244474606 scopus 로고    scopus 로고
    • Interleukin-13-regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis
    • DOI 10.1158/0008-5472.CAN-05-0045
    • P. Sinha, V. K. Clements and S. Ostrand-Rosenberg: Interleukin-13- regulated M2 macrophages in combination with myeloid suppressor cells block immune surveillance against metastasis. Cancer Res 65, 11743-11751 (2005). (Pubitemid 41821736)
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11743-11751
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 131
    • 31544446571 scopus 로고    scopus 로고
    • + immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • DOI 10.1158/0008-5472.CAN-05-1299
    • B. Huang, P. Y. Pan, Q. Li, A. I. Sato, D. E. Levy, J. Bromberg, C. M. Divino and S. H. Chen: Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and Tcell anergy in tumor-bearing host. Cancer Res 66, 1123- 1131 (2006). (Pubitemid 43165981)
    • (2006) Cancer Research , vol.66 , Issue.2 , pp. 1123-1131
    • Huang, B.1    Pan, P.-Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.-H.8
  • 132
    • 38049181485 scopus 로고    scopus 로고
    • Reversion of immune tolerance in advanced malignancy: Modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function
    • P. Y. Pan, G. X. Wang, B. Yin, J. Ozao, T. Ku, C. M. Divino and S. H. Chen: Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function. Blood 111, 219-228 (2008).
    • (2008) Blood , vol.111 , pp. 219-228
    • Pan, P.Y.1    Wang, G.X.2    Yin, B.3    Ozao, J.4    Ku, T.5    Divino, C.M.6    Chen, S.H.7
  • 133
    • 34248342290 scopus 로고    scopus 로고
    • Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumor-bearing host
    • DOI 10.1182/blood-2006-09-046201
    • C. Liu, S. Yu, J. Kappes, J. Wang, W. E. Grizzle, K. R. Zinn and H. G. Zhang: Expansion of spleen myeloid suppressor cells represses NK cell cytotoxicity in tumorbearing host. Blood 109, 4336-4342 (2007). (Pubitemid 46743401)
    • (2007) Blood , vol.109 , Issue.10 , pp. 4336-4342
    • Liu, C.1    Yu, S.2    Kappes, J.3    Wang, J.4    Grizzle, W.E.5    Zinn, K.R.6    Zhang, H.-G.7
  • 134
    • 25144466458 scopus 로고    scopus 로고
    • + myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • DOI 10.1158/1078-0432.CCR-05-0883
    • E. Suzuki, V. Kapoor, A. S. Jassar, L. R. Kaiser and S. M. Albelda: Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 11, 6713-6721 (2005). (Pubitemid 41339014)
    • (2005) Clinical Cancer Research , vol.11 , Issue.18 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3    Kaiser, L.R.4    Albelda, S.M.5
  • 135
    • 34548805636 scopus 로고    scopus 로고
    • Cross-talk between myeloidderived suppressor cells and macrophages subverts tumor immunity toward a type 2 response
    • P. Sinha, V. K. Clements, S. K. Bunt, S. M. Albelda and S. Ostrand-Rosenberg: Cross-talk between myeloidderived suppressor cells and macrophages subverts tumor immunity toward a type 2 response. J Immunol 179, 977- 983 (2007).
    • (2007) J Immunol , vol.179 , pp. 977-983
    • Sinha, P.1    Clements, V.K.2    Bunt, S.K.3    Albelda, S.M.4    Ostrand-Rosenberg, S.5
  • 137
    • 0030613856 scopus 로고    scopus 로고
    • Requirement for V(α)14 NKT cells in IL-12-mediated rejection of tumors
    • DOI 10.1126/science.278.5343.1623
    • J. Cui, T. Shin, T. Kawano, H. Sato, E. Kondo, I. Toura, Y. Kaneko, H. Koseki, M. Kanno and M. Taniguchi: Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumors. Science 278, 1623-1626 (1997). (Pubitemid 27516281)
    • (1997) Science , vol.278 , Issue.5343 , pp. 1623-1626
    • Cui, J.1    Shin, T.2    Kawano, T.3    Sato, H.4    Kondo, E.5    Toura, I.6    Kaneko, Y.7    Koseki, H.8    Kanno, M.9    Taniguchi, M.10
  • 140
    • 10744220561 scopus 로고    scopus 로고
    • Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte-mediated Tumor Immunosurveillance: Abrogation Prevents Tumor Recurrence
    • DOI 10.1084/jem.20022227
    • M. Terabe, S. Matsui, J. M. Park, M. Mamura, N. Noben-Trauth, D. D. Donaldson, W. Chen, S. M. Wahl, S. Ledbetter, B. Pratt, J. J. Letterio, W. E. Paul and J. A. Berzofsky: Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocytemediated tumor immunosurveillance: abrogation prevents tumor recurrence. J Exp Med 198, 1741-1752 (2003). (Pubitemid 37494166)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.11 , pp. 1741-1752
    • Terabe, M.1    Matsui, S.2    Park, J.-M.3    Mamura, M.4    Noben-Trauth, N.5    Donaldson, D.D.6    Chen, W.7    Wahl, S.M.8    Ledbetter, S.9    Pratt, B.10    Letterio, J.J.11    Paul, W.E.12    Berzofsky, J.A.13
  • 143
    • 0037111416 scopus 로고    scopus 로고
    • Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-γ dependent
    • S. Ostrand-Rosenberg, V. K. Clements, M. Terabe, J. M. Park, J. A. Berzofsky and S. K. Dissanayake: Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFNgamma dependent. J Immunol 169, 5796-5804 (2002). (Pubitemid 35291682)
    • (2002) Journal of Immunology , vol.169 , Issue.10 , pp. 5796-5804
    • Ostrand-Rosenberg, S.1    Clements, V.K.2    Terabe, M.3    Park, J.M.4    Berzofsky, J.A.5    Dissanayake, S.K.6
  • 144
    • 33645732440 scopus 로고    scopus 로고
    • CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta
    • M. Terabe, C. Khanna, S. Bose, F. Melchionda, A. Mendoza, C. L. Mackall, L. J. Helman and J. A. Berzofsky: CD1d-restricted natural killer T cells can down-regulate tumor immunosurveillance independent of interleukin-4 receptor-signal transducer and activator of transcription 6 or transforming growth factor-beta. Cancer Res 66, 3869- 3875 (2006).
    • (2006) Cancer Res , vol.66 , pp. 3869-3875
    • Terabe, M.1    Khanna, C.2    Bose, S.3    Melchionda, F.4    Mendoza, A.5    Mackall, C.L.6    Helman, L.J.7    Berzofsky, J.A.8
  • 146
    • 36048995442 scopus 로고    scopus 로고
    • NKT cells in immunoregulation of tumor immunity: A new immunoregulatory axis
    • DOI 10.1016/j.it.2007.05.008, PII S1471490607002293
    • M. Terabe and J. A. Berzofsky: NKT cells in immunoregulation of tumor immunity: a new immunoregulatory axis. Trends Immunol 28, 491-496 (2007). (Pubitemid 350087811)
    • (2007) Trends in Immunology , vol.28 , Issue.11 , pp. 491-496
    • Terabe, M.1    Berzofsky, J.A.2
  • 149
    • 0037093058 scopus 로고    scopus 로고
    • Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli
    • DOI 10.1182/blood.V99.10.3838
    • M. Di Nicola, C. Carlo-Stella, M. Magni, M. Milanesi, P. D. Longoni, P. Matteucci, S. Grisanti and A. M. Gianni: Human bone marrow stromal cells suppress Tlymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli. Blood 99, 3838-3843 (2002). (Pubitemid 34534559)
    • (2002) Blood , vol.99 , Issue.10 , pp. 3838-3843
    • Nicola, M.D.1    Carlo-Stella, C.2    Magni, M.3    Milanesi, M.4    Longoni, P.D.5    Matteucci, P.6    Grisanti, S.7    Gianni, A.M.8
  • 150
    • 0038204193 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide
    • DOI 10.1182/blood-2002-07-2104
    • M. Krampera, S. Glennie, J. Dyson, D. Scott, R. Laylor, E. Simpson and F. Dazzi: Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide. Blood 101, 3722-3729 (2003). (Pubitemid 36857965)
    • (2003) Blood , vol.101 , Issue.9 , pp. 3722-3729
    • Krampera, M.1    Glennie, S.2    Dyson, J.3    Scott, D.4    Laylor, R.5    Simpson, E.6    Dazzi, F.7
  • 151
    • 15944376184 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells
    • DOI 10.1182/blood-2004-09-3696
    • S. Glennie, I. Soeiro, P. J. Dyson, E. W. Lam and F. Dazzi: Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cells. Blood 105, 2821-2827 (2005). (Pubitemid 40446275)
    • (2005) Blood , vol.105 , Issue.7 , pp. 2821-2827
    • Glennie, S.1    Soeiro, I.2    Dyson, P.J.3    Lam, E.W.-F.4    Dazzi, F.5
  • 152
    • 26944439542 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce apoptosis of activated T cells
    • DOI 10.1038/sj.leu.2403871, PII 2403871
    • J. Plumas, L. Chaperot, M. J. Richard, J. P. Molens, J. C. Bensa and M. C. Favrot: Mesenchymal stem cells induce apoptosis of activated T cells. Leukemia 19, 1597-1604 (2005). (Pubitemid 43090404)
    • (2005) Leukemia , vol.19 , Issue.9 , pp. 1597-1604
    • Plumas, J.1    Chaperot, L.2    Richard, M.-J.3    Molens, J.-P.4    Bensa, J.-C.5    Favrot, M.-C.6
  • 153
    • 14944339174 scopus 로고    scopus 로고
    • Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness
    • DOI 10.1182/blood-2004-07-2921
    • S. Beyth, Z. Borovsky, D. Mevorach, M. Liebergall, Z. Gazit, H. Aslan, E. Galun and J. Rachmilewitz: Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 105, 2214-2219 (2005). (Pubitemid 40731815)
    • (2005) Blood , vol.105 , Issue.5 , pp. 2214-2219
    • Beyth, S.1    Borovsky, Z.2    Mevorach, D.3    Liebergall, M.4    Gazit, Z.5    Aslan, H.6    Galun, E.7    Rachmilewitz, J.8
  • 154
    • 33746898242 scopus 로고    scopus 로고
    • +-derived and monocyte-derived dendritic cells
    • A. J. Nauta, A. B. Kruisselbrink, E. Lurvink, R. Willemze and W. E. Fibbe: Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cells. J Immunol 177, 2080-2087 (2006). (Pubitemid 44200965)
    • (2006) Journal of Immunology , vol.177 , Issue.4 , pp. 2080-2087
    • Nauta, A.J.1    Kruisselbrink, A.B.2    Lurvink, E.3    Willemze, R.4    Fibbe, W.E.5
  • 155
    • 33846220680 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle
    • DOI 10.1097/01.tp.0000244572.24780.54, PII 0000789020070115000014
    • R. Ramasamy, H. Fazekasova, E. W. Lam, I. Soeiro, G. Lombardi and F. Dazzi: Mesenchymal stem cells inhibit dendritic cell differentiation and function by preventing entry into the cell cycle. Transplantation 83, 71-76 (2007). (Pubitemid 46104974)
    • (2007) Transplantation , vol.83 , Issue.1 , pp. 71-76
    • Ramasamy, R.1    Fazekasova, H.2    Lam, E.W.-F.3    Soeiro, I.4    Lombardi, G.5    Dazzi, F.6
  • 157
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation
    • DOI 10.1182/blood-2005-07-2775
    • G. M. Spaggiari, A. Capobianco, S. Becchetti, M. C. Mingari and L. Moretta: Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2- induced NK-cell proliferation. Blood 107, 1484-1490 (2006). (Pubitemid 43242385)
    • (2006) Blood , vol.107 , Issue.4 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3    Mingari, M.C.4    Moretta, L.5
  • 158
    • 38449121250 scopus 로고    scopus 로고
    • The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells
    • S. Jones, N. Horwood, A. Cope and F. Dazzi: The antiproliferative effect of mesenchymal stem cells is a fundamental property shared by all stromal cells. J Immunol 179, 2824-2831 (2007).
    • (2007) J Immunol , vol.179 , pp. 2824-2831
    • Jones, S.1    Horwood, N.2    Cope, A.3    Dazzi, F.4
  • 159
    • 34548604258 scopus 로고    scopus 로고
    • Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells
    • M. A. Haniffa, X. N. Wang, U. Holtick, M. Rae, J. D. Isaacs, A. M. Dickinson, C. M. Hilkens and M. P. Collin: Adult human fibroblasts are potent immunoregulatory cells and functionally equivalent to mesenchymal stem cells. J Immunol 179, 1595-1604 (2007).
    • (2007) J Immunol , vol.179 , pp. 1595-1604
    • Haniffa, M.A.1    Wang, X.N.2    Holtick, U.3    Rae, M.4    Isaacs, J.D.5    Dickinson, A.M.6    Hilkens, C.M.7    Collin, M.P.8
  • 160
    • 53549114488 scopus 로고    scopus 로고
    • Is IDO a key enzyme bridging the gap between tumor escape and tolerance induction?
    • S. Lob and A. Konigsrainer: Is IDO a key enzyme bridging the gap between tumor escape and tolerance induction? Langenbecks Arch Surg (2007).
    • (2007) Langenbecks Arch Surg
    • Lob, S.1    Konigsrainer, A.2
  • 161
    • 16244409219 scopus 로고    scopus 로고
    • Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer
    • DOI 10.1038/sj.bjc.6602407
    • C. Schaefer, G. G. Kim, A. Albers, K. Hoermann, E. N. Myers and T. L. Whiteside: Characteristics of CD4+CD25+ regulatory T cells in the peripheral circulation of patients with head and neck cancer. Br J Cancer 92, 913-920 (2005). (Pubitemid 40462639)
    • (2005) British Journal of Cancer , vol.92 , Issue.5 , pp. 913-920
    • Schaefer, C.1    Kim, G.G.2    Albers, A.3    Hoermann, K.4    Myers, E.N.5    Whiteside, T.L.6
  • 162
    • 0035876913 scopus 로고    scopus 로고
    • + regulatory t cells from human peripheral blood
    • S. Yamagiwa, J. D. Gray, S. Hashimoto and D. A. Horwitz: A role for TGF-beta in the generation and expansion of CD4+CD25+ regulatory T cells from human peripheral blood. J Immunol 166, 7282-7289 (2001). (Pubitemid 32525603)
    • (2001) Journal of Immunology , vol.166 , Issue.12 , pp. 7282-7289
    • Yamagiwa, S.1    Gray, J.D.2    Hashimoto, S.3    Horwitz, D.A.4
  • 166
    • 1642497640 scopus 로고    scopus 로고
    • + Regulatory T Cells and Their Ligands: Implications for Immunotherapy
    • DOI 10.1016/S1074-7613(03)00359-5
    • H. Y. Wang, D. A. Lee, G. Peng, Z. Guo, Y. Li, Y. Kiniwa, E. M. Shevach and R. F. Wang: Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity 20, 107-118 (2004). (Pubitemid 38134298)
    • (2004) Immunity , vol.20 , Issue.1 , pp. 107-118
    • Wang, H.Y.1    Lee, D.A.2    Peng, G.3    Guo, Z.4    Li, Y.5    Kiniwa, Y.6    Shevach, E.M.7    Wang, R.-F.8
  • 167
    • 0029842830 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells
    • DOI 10.1038/nm1096-1096
    • D. I. Gabrilovich, H. L. Chen, K. R. Girgis, H. T. Cunningham, G. M. Meny, S. Nadaf, D. Kavanaugh and D. P. Carbone: Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nat Med 2, 1096-1103 (1996). (Pubitemid 26338628)
    • (1996) Nature Medicine , vol.2 , Issue.10 , pp. 1096-1103
    • Gabrilovich, D.I.1    Chen, H.L.2    Girgis, K.R.3    Cunningham, H.T.4    Meny, G.M.5    Nadaf, S.6    Kavanaugh, D.7    Carbone, D.P.8
  • 168
    • 0032400862 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo
    • D. Gabrilovich, T. Ishida, T. Oyama, S. Ran, V. Kravtsov, S. Nadaf and D. P. Carbone: Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo. Blood 92, 4150- 4166 (1998). (Pubitemid 28544331)
    • (1998) Blood , vol.92 , Issue.11 , pp. 4150-4166
    • Gabrilovich, D.1    Ishida, T.2    Oyama, T.3    Ran, S.4    Kravtsov, V.5    Nadaf, S.6    Carbone, D.P.7
  • 169
    • 33845547203 scopus 로고    scopus 로고
    • Intratumoral cytokines/chemokines/growth factors and tumor infiltrating dendritic cells: Friends or enemies?
    • DOI 10.1007/s10555-006-9010-6, Special Issue on Pro-inflammatory Cytokines in Cancer
    • M. R. Shurin, G. V. Shurin, A. Lokshin, Z. R. Yurkovetsky, D. W. Gutkin, G. Chatta, H. Zhong, B. Han and R. L. Ferris: Intratumoral cytokines/chemokines/ growth factors and tumor infiltrating dendritic cells: friends or enemies? Cancer Metastasis Rev 25, 333-356 (2006). (Pubitemid 44922354)
    • (2006) Cancer and Metastasis Reviews , vol.25 , Issue.3 , pp. 333-356
    • Shurin, M.R.1    Shurin, G.V.2    Lokshin, A.3    Yurkovetsky, Z.R.4    Gutkin, D.W.5    Chatta, G.6    Zhong, H.7    Han, B.8    Ferris, R.L.9
  • 172
    • 0033903714 scopus 로고    scopus 로고
    • Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer
    • T. Ueno, M. Toi, H. Saji, M. Muta, H. Bando, K. Kuroi, M. Koike, H. Inadera and K. Matsushima: Significance of macrophage chemoattractant protein-1 in macrophage recruitment, angiogenesis, and survival in human breast cancer. Clin Cancer Res 6, 3282-3289 (2000). (Pubitemid 30637758)
    • (2000) Clinical Cancer Research , vol.6 , Issue.8 , pp. 3282-3289
    • Ueno, T.1    Toi, M.2    Saji, H.3    Muta, M.4    Bando, H.5    Kuroi, K.6    Koike, M.7    Inadera, H.8    Matsushima, K.9
  • 173
    • 0036174325 scopus 로고    scopus 로고
    • The CC chemokine RANTES in breast carcinoma progression: Regulation of expression and potential mechanisms of promalignant activity
    • E. Azenshtein, G. Luboshits, S. Shina, E. Neumark, D. Shahbazian, M. Weil, N. Wigler, I. Keydar and A. Ben Baruch: The CC chemokine RANTES in breast carcinoma progression: regulation of expression and potential mechanisms of promalignant activity. Cancer Res 62, 1093-1102 (2002). (Pubitemid 34160293)
    • (2002) Cancer Research , vol.62 , Issue.4 , pp. 1093-1102
    • Azenshtein, E.1    Luboshits, G.2    Shina, S.3    Neumark, E.4    Shahbazian, D.5    Weil, M.6    Wigler, N.7    Keydar, I.8    Ben-Baruch, A.9
  • 174
    • 0035447414 scopus 로고    scopus 로고
    • Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma
    • DOI 10.1002/1097-0142(20010901)92:5<1085::AID-CNCR1424>3.0.CO;2-K
    • H. Saji, M. Koike, T. Yamori, S. Saji, M. Seiki, K. Matsushima and M. Toi: Significant correlation of monocyte chemoattractant protein-1 expression with neovascularization and progression of breast carcinoma. Cancer 92, 1085-1091 (2001). (Pubitemid 32861655)
    • (2001) Cancer , vol.92 , Issue.5 , pp. 1085-1091
    • Saji, H.1    Koike, M.2    Yamori, T.3    Saji, S.4    Seiki, M.5    Matsushima, K.6    Toi, M.7
  • 175
    • 0036174025 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-165 overexpression stimulates angiogenesis and induces cyst formation and macrophage infiltration in human ovarian cancer xenografts
    • M. C. Duyndam, M. C. Hilhorst, H. M. Schluper, H. M. Verheul, P. J. van Diest, G. Kraal, H. M. Pinedo and E. Boven: Vascular endothelial growth factor-165 overexpression stimulates angiogenesis and induces cyst formation and macrophage infiltration in human ovarian cancer xenografts. Am J Pathol 160, 537-548 (2002). (Pubitemid 34160331)
    • (2002) American Journal of Pathology , vol.160 , Issue.2 , pp. 537-548
    • Duyndam, M.C.A.1    Hilhorst, M.C.G.W.2    Schluper, H.M.M.3    Verheul, H.M.W.4    Van Diest, P.J.5    Kraal, G.6    Pinedo, H.M.7    Boven, E.8
  • 177
    • 11844277698 scopus 로고    scopus 로고
    • Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease
    • P. Sinha, V. K. Clements and S. Ostrand-Rosenberg: Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease. J Immunol 174, 636-645 (2005). (Pubitemid 40094255)
    • (2005) Journal of Immunology , vol.174 , Issue.2 , pp. 636-645
    • Sinha, P.1    Clements, V.K.2    Ostrand-Rosenberg, S.3
  • 178
    • 0034651585 scopus 로고    scopus 로고
    • Resection of solid tumors reverses T cell defects and restores protective immunity
    • S. Salvadori, G. Martinelli and K. Zier: Resection of solid tumors reverses T cell defects and restores protective immunity. J Immunol 164, 2214-2220 (2000). (Pubitemid 30108782)
    • (2000) Journal of Immunology , vol.164 , Issue.4 , pp. 2214-2220
    • Salvadori, S.1    Martinelli, G.2    Zier, K.3
  • 179
    • 0141456030 scopus 로고    scopus 로고
    • Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity
    • DOI 10.1182/blood-2003-01-0190
    • C. Melani, C. Chiodoni, G. Forni and M. P. Colombo: Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity. Blood 102, 2138-2145 (2003). (Pubitemid 37122391)
    • (2003) Blood , vol.102 , Issue.6 , pp. 2138-2145
    • Melani, C.1    Chiodoni, C.2    Forni, G.3    Colombo, M.P.4
  • 180
    • 0034790570 scopus 로고    scopus 로고
    • Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colonystimulating factor and granulocyte-macrophage colony-stimulating factor
    • M. M. Mueller, W. Peter, M. Mappes, A. Huelsen, H. Steinbauer, P. Boukamp, M. Vaccariello, J. Garlick and N. E. Fusenig: Tumor progression of skin carcinoma cells in vivo promoted by clonal selection, mutagenesis, and autocrine growth regulation by granulocyte colonystimulating factor and granulocyte-macrophage colonystimulating factor. Am J Pathol 159, 1567-1579 (2001). (Pubitemid 32947984)
    • (2001) American Journal of Pathology , vol.159 , Issue.4 , pp. 1567-1579
    • Mueller, M.M.1    Peter, W.2    Mappes, M.3    Huelsen, A.4    Steinbauer, H.5    Boukamp, P.6    Vaccariello, M.7    Garlick, J.8    Fusenig, N.E.9
  • 182
    • 0034785219 scopus 로고    scopus 로고
    • Tumor-derived granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor prolong the survival of neutrophils infiltrating bronchoalveolar subtype pulmonary adenocarcinoma
    • M. Wislez, J. Fleury-Feith, N. Rabbe, J. Moreau, D. Cesari, B. Milleron, C. Mayaud, M. Antoine, P. Soler and J. Cadranel: Tumor-derived granulocyte-macrophage colony-stimulating factor and granulocyte colonystimulating factor prolong the survival of neutrophils infiltrating bronchoalveolar subtype pulmonary adenocarcinoma. Am J Pathol 159, 1423-1433 (2001). (Pubitemid 32947972)
    • (2001) American Journal of Pathology , vol.159 , Issue.4 , pp. 1423-1433
    • Wislez, M.1    Fleury-Feith, J.2    Rabbe, N.3    Moreau, J.4    Cesari, D.5    Milleron, B.6    Mayaud, C.7    Antoine, M.8    Soler, P.9    Cadranel, J.10
  • 183
    • 34248172324 scopus 로고    scopus 로고
    • Altered macrophage differentiation and immune dysfunction in tumor development
    • DOI 10.1172/JCI31422
    • A. Sica and V. Bronte: Altered macrophage differentiation and immune dysfunction in tumor development. J Clin Invest 117, 1155-1166 (2007). (Pubitemid 46718400)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.5 , pp. 1155-1166
    • Sica, A.1    Bronte, V.2
  • 184
    • 42149099408 scopus 로고    scopus 로고
    • Plasticity of macrophage function during tumor progression: Regulation by distinct molecular mechanisms
    • S. K. Biswas, A. Sica and C. E. Lewis: Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms. J Immunol 180, 2011- 2017 (2008).
    • (2008) J Immunol , vol.180 , pp. 2011-2017
    • Biswas, S.K.1    Sica, A.2    Lewis, C.E.3
  • 185
    • 33845752914 scopus 로고    scopus 로고
    • P50 nuclear factor-κB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance
    • DOI 10.1158/0008-5472.CAN-06-1867
    • A. Saccani, T. Schioppa, C. Porta, S. K. Biswas, M. Nebuloni, L. Vago, B. Bottazzi, M. P. Colombo, A. Mantovani and A. Sica: p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance. Cancer Res 66, 11432-11440 (2006). (Pubitemid 46009975)
    • (2006) Cancer Research , vol.66 , Issue.23 , pp. 11432-11440
    • Saccani, A.1    Schioppa, T.2    Porta, C.3    Biswas, S.K.4    Nebuloni, M.5    Vago, L.6    Bottazzi, B.7    Colombo, M.P.8    Mantovani, A.9    Sica, A.10
  • 186
    • 0142137237 scopus 로고    scopus 로고
    • Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
    • DOI 10.1038/nm934
    • C. Uyttenhove, L. Pilotte, I. Theate, V. Stroobant, D. Colau, N. Parmentier, T. Boon and B. J. Van den Eynde: Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2, 3-dioxygenase. Nat Med 9, 1269-1274 (2003). (Pubitemid 37279849)
    • (2003) Nature Medicine , vol.9 , Issue.10 , pp. 1269-1274
    • Uyttenhove, C.1    Pilotte, L.2    Theate, I.3    Stroobant, V.4    Colau, D.5    Parmentier, N.6    Boon, T.7    Van Den Eynde, B.J.8
  • 187
    • 42249084713 scopus 로고    scopus 로고
    • Inverse correlation between tumoral indoleamine 2,3-dioxygenase expression and tumor-infiltrating lymphocytes in endometrial cancer: Its association with disease progression and survival
    • DOI 10.1158/1078-0432.CCR-07-4144
    • K. Ino, E. Yamamoto, K. Shibata, H. Kajiyama, N. Yoshida, M. Terauchi, A. Nawa, T. Nagasaka, O. Takikawa and F. Kikkawa: Inverse correlation between tumoral indoleamine 2, 3-dioxygenase expression and tumorinfiltrating lymphocytes in endometrial cancer: its association with disease progression and survival. Clin Cancer Res 14, 2310-2317 (2008). (Pubitemid 351551062)
    • (2008) Clinical Cancer Research , vol.14 , Issue.8 , pp. 2310-2317
    • Ino, K.1    Yamamoto, E.2    Shibata, K.3    Kajiyama, H.4    Yoshida, N.5    Terauchi, M.6    Nawa, A.7    Nagasaka, T.8    Takikawa, O.9    Kikkawa, F.10
  • 188
    • 5044220930 scopus 로고    scopus 로고
    • IDO expression by dendritic cells: Tolerance and tryptophan catabolism
    • DOI 10.1038/nri1457
    • A. L. Mellor and D. H. Munn: IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 4, 762-774 (2004). (Pubitemid 39336293)
    • (2004) Nature Reviews Immunology , vol.4 , Issue.10 , pp. 762-774
    • Mellor, A.L.1    Munn, D.H.2
  • 190
    • 33750699056 scopus 로고    scopus 로고
    • The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function
    • DOI 10.1182/blood-2006-03-006700
    • C. M. Della, S. Carlomagno, G. Frumento, M. Balsamo, C. Cantoni, R. Conte, L. Moretta, A. Moretta and M. Vitale: The tryptophan catabolite L-kynurenine inhibits the surface expression of NKp46- and NKG2D-activating receptors and regulates NK-cell function. Blood 108, 4118- 4125 (2006). (Pubitemid 44913283)
    • (2006) Blood , vol.108 , Issue.13 , pp. 4118-4125
    • Della Chiesa, M.1    Carlomagno, S.2    Frumento, G.3    Balsamo, M.4    Cantoni, C.5    Conte, R.6    Moretta, L.7    Moretta, A.8    Vitale, M.9


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