From Vanilla to 28 Flavors: Multiple Varieties of T Regulatory Cells

Immunity

Volumn 25, Issue 2, 2006, Pages 195-201

  Shevach, Ethan M ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; SMAD7 PROTEIN; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

ALLERGIC ENCEPHALOMYELITIS; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN RECOGNITION; ARTICLE; AUTOIMMUNE DISEASE; CD4+ CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ISOLATION; CELL POPULATION; DOWN REGULATION; EFFECTOR CELL; FLOW CYTOMETRY; HUMAN; IMMUNOREGULATION; IPEX SYNDROME; KNOCKOUT MOUSE; LYMPHOCYTE CULTURE; LYMPHOCYTE DEPLETION; MAJOR HISTOCOMPATIBILITY COMPLEX; NONHUMAN; PLASMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY T LYMPHOCYTE; SPECIES COMPARISON; SUPPRESSOR CELL; T LYMPHOCYTE SUBPOPULATION; TRANSCRIPTION REGULATION; WILD TYPE;

EID: 33747143361     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.08.003     Document Type: Note

References (41)

1. Apostolou I., and von Boehmer H. In vivo instruction of suppressor commitment in naive T cells. J. Exp. Med. 199 (2004) 1401-1408
2. high regulatory cells in human peripheral blood. J. Immunol. 167 (2001) 1245-1253
3. H17 and regulatory T cells. Nature 441 (2006) 235-238
4. + T lymphocytes from MHC class II-deficient mice exhibit regulatory activity. J. Immunol. 175 (2005) 246-253
5. + regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 165 (2003) 1875-1886
6. Chen W., Zhou D., Torreabla J.R., Waddell T.K., Grant D., and Zhang L. Donor lymphocyte infusion induces long-term donor-specific cardiac xenograft survival through activation or recipient double-negative regulatory T cells. J. Immunol. 175 (2005) 3409-3416
7. Cobbold S.P., Castejon R., Adams E., Zelenika D., Graca L., Humm S., and Waldmann H. Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants. J. Immunol. 172 (2004) 6003-6010
8. + regulatory thymocytes. Blood 102 (2003) 4107-4144
9. Endharti A.T., Rifa'I M., Shi Z., Fukuoka Y., Nakahara Y., Kawamoto Y., Takeda K., Isobe K., and Suzuki H. Cutting edge: CD8+CD122+ regulatory T cells produce IL-10 to suppress IFN-g production and proliferation of CD8+ T cells. J. Immunol. 175 (2005) 7093-7097
10. Fantini M.C., Becker C., Monteleone G., Pallone F., Galle P.R., and Neurath M.F. J. Immunol. 172 (2004) 5149-5153
11. - double-negative regulatory T cells. Blood 105 (2005) 2828-2835
12. Fontenot J.D., Rasmussen J.P., Williams L.M., Dooley J.L., Farr A.G., and Rudensky A.Y. Regulatory T cell lineage specification by the forkhead transcription factor foxp3. Immunity 22 (2005) 329-341
13. Gavin M.A., Torgerssson T.R., Houston E.R., de Roos P., Ho W.Y., Stray-Pedersen A., Ocheltre E.L., Greenberg P.D., Ochs H.D., and Rudensky A.Y. Single-cell analysis of normal and Foxp3-mutant human T cells: Foxp3 expression without regulatory T cell development. Proc. Natl. Acad. Sci. USA 103 (2006) 6659-6664
14. Gershon R.K., Eardley D.D., Naidorf K.F., and Ptak W. Hermaphrocyte-suppressor-helper T cell. Cold Spring Harb. Symp. Quant. Biol. 41 (1976) 85-91
15. Gilliet M., and Liu Y.-J. Generation of CD8 T regulatory cells by CD40 ligand activated plasmacytoid dendritic cells. J. Exp. Med. 195 (2002) 695-704
16. + T cell suppressors. J. Immunol. 175 (2005) 7728-7737
17. Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
18. + regulatory T cells. J. Exp. Med. 199 (2004) 303-313
19. + T cells with a regulatory phenotype and function. Eur. J. Immunol. 35 (2005) 2896-2908
20. Jiang H., and Chess L. The specific regulation of immune responses by CD8+ T cells restricted by the MHC class IB molecule, QA-1. Annu. Rev. Immunol. 18 (2000) 185-216
21. + cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature 421 (2003) 388-392
22. Knoechel B., Lohr J., Kahn E., Bluestone J.A., and Abbas A.K. Sequential, development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J. Exp. Med. 202 (2005) 1375-1386
23. Knoechel B., Lohr J., Zhu S., Wong L., Hu D., Ausubel L., and Abbas A.K. Functional and molecular comparison of anergic and regulatory T lymphocytes. J. Immunol. 176 (2006) 6473-6483
24. Kretschmer K., Apostolou I., Hawiger D., Khazaie K., Nussenzweig M.C., and von Boehmer H. Inducing and expanding regulatory T cell populations by foreign antigen. Nat. Immunol. 6 (2005) 1219-1227
25. + CTLs by TCR Vbeta-derived peptides bound to HLA-E. J. Immunol. 167 (2001) 3800-3808
26. Liu W., Putnam A.L., Xu-yu Z., Szot G.L., Lee M.R., Zhu S., Gottlieb P.A., Kapranov P., Gingeras T.R., de St. Groth B.F., et al. CD127 expression inversely correlates with Foxp3 and suppressive function of human CD4+ T reg cells. J. Exp. Med. 203 (2006) 1701-1711
27. Mills K.H. Regulatory T cells: Friend or for in immunity to infection?. Nat. Rev. Immunol. 4 (2004) 841-855
28. Ochando J.C., Homma C., Yang Y., Hidalgo A., Garin A., Tacke F., Angeli V., Li Y., Boros P., Ding Y., et al. Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts. Nat. Immunol. 7 (2006) 652-662
29. O'Garra A., and Vieira P. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10 (2004) 801-805
30. + immunoregulatory cells. J. Immunol. 167 (2001) 1137-1140
31. Rifa'i M., Kawamoto Y., Nakashima I., and Suzuki H. Essential roles of CD8+CD122+ regulatory T cells in the maintenance of T cell homeostasis. J. Exp. Med. 200 (2004) 1123-1134
32. Sakaguchi S., Sakaguchi N., Asano M., Itoh M., and Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains(CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155 (1995) 1151-1164
33. + suppressor T cells. J. Exp. Med. 193 (2001) F41-F45
34. + natural regulatory T cells are specific for microbial antigens. J. Exp. Med. 203 (2006) 777-788
35. + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188 (1998) 287-296
36. + regulatory T cells. J. Immunol. 172 (2004) 5986-5993
37. Vlad G., Cortesini R., and Suciu-Foca N. License to heal: Bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC. J. Immunol. 174 (2005) 5907-5914
38. + regulatory T cells in human ovarian carcinoma. Cancer Res. 65 (2005) 5020-5026
39. Xystrakis E., Dejean A.S., Bernard I., Druet P., Liblau R., Gonzalez-Dunia D., and Saoudi A. Identification of a novel natural regulatory CD8 T cell subset and analysis of its mechanism of regulation. Blood 104 (2004) 3294-3301
40. + regulatory T cells from human peripheral blood. J. Immunol. 166 (2001) 7282-7289
41. + T cells selectively kill B lymphocytes. Blood 107 (2006) 3925-3932