-
1
-
-
0030807565
-
Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy
-
Wick, M., P. Dubey, H. Koeppen, C.T. Siegel, P.E. Fields, L. Chen, J.A. Bluestone, and H. Schreiber. 1997. Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy. J. Exp. Med. 186:229-238.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 229-238
-
-
Wick, M.1
Dubey, P.2
Koeppen, H.3
Siegel, C.T.4
Fields, P.E.5
Chen, L.6
Bluestone, J.A.7
Schreiber, H.8
-
3
-
-
0033103021
-
A new era for cancer immunotherapy based on the genes that encode cancer antigens
-
Rosenberg, S.A. 1999. A new era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity. 10:281-287.
-
(1999)
Immunity
, vol.10
, pp. 281-287
-
-
Rosenberg, S.A.1
-
4
-
-
0042470540
-
Does the immune system see tumors as foreign or self?
-
Pardoll, D. 2003. Does the immune system see tumors as foreign or self? Annu. Rev. Immunol. 21:807-839.
-
(2003)
Annu. Rev. Immunol.
, vol.21
, pp. 807-839
-
-
Pardoll, D.1
-
5
-
-
0028947046
-
A unique tumor antigen produced by a single amino acid substitution
-
Monach, P.A., S.C. Meredith, C.T. Siegel, and H. Schreiber. 1995. A unique tumor antigen produced by a single amino acid substitution. Immunity. 2:45-59.
-
(1995)
Immunity
, vol.2
, pp. 45-59
-
-
Monach, P.A.1
Meredith, S.C.2
Siegel, C.T.3
Schreiber, H.4
-
6
-
-
0029125899
-
A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma
-
Coulie, P.G., F. Lehmann, B. Lethe, J. Herman, C. Lurquin, M. Andrawiss, and T. Boon. 1995. A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma. Proc. Natl. Acad. Sci. USA. 92:7976-7980.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7976-7980
-
-
Coulie, P.G.1
Lehmann, F.2
Lethe, B.3
Herman, J.4
Lurquin, C.5
Andrawiss, M.6
Boon, T.7
-
7
-
-
0028978274
-
A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma
-
Wolfel, T., M. Hauer, J. Schneider, M. Serrano, C. Wolfel, E. Klehmann-Hieb, E. De Plaen, T. Hankein, K.H. Meyer zum Buschenfelde, and D. Beach. 1995. A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma. Science. 269:1281-1284.
-
(1995)
Science
, vol.269
, pp. 1281-1284
-
-
Wolfel, T.1
Hauer, M.2
Schneider, J.3
Serrano, M.4
Wolfel, C.5
Klehmann-Hieb, E.6
De Plaen, E.7
Hankein, T.8
Meyer Zum Buschenfelde, K.H.9
Beach, D.10
-
8
-
-
0024121486
-
Immunogenic (tum-) variants of mouse tumor P815: Cloning of the gene of tum- antigen P91A and identification of the tum- mutation
-
De Plaen, E., C. Lurquin, A. Van Pel, B. Mariame, J.P. Szikora, T. Wolfel, C. Sibille, P. Chomez, and T. Boon. 1988. Immunogenic (tum-) variants of mouse tumor P815: cloning of the gene of tum- antigen P91A and identification of the tum- mutation. Proc. Natl. Acad. Sci. USA. 85:2274-2278.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 2274-2278
-
-
De Plaen, E.1
Lurquin, C.2
Van Pel, A.3
Mariame, B.4
Szikora, J.P.5
Wolfel, T.6
Sibille, C.7
Chomez, P.8
Boon, T.9
-
9
-
-
0024316157
-
Structure of the gene of tum- transplantation antigen P91A: The mutated exon encodes a peptide recognized with Ld by cytolytic T cells
-
Lurquin, C., A. Van Pel, B. Mariame, E. De Plaen, J.P. Szikora, C. Janssens, M.J. Reddehase, J. Lejeune, and T. Boon. 1989. Structure of the gene of tum- transplantation antigen P91A: the mutated exon encodes a peptide recognized with Ld by cytolytic T cells. Cell. 58:293-303.
-
(1989)
Cell
, vol.58
, pp. 293-303
-
-
Lurquin, C.1
Van Pel, A.2
Mariame, B.3
De Plaen, E.4
Szikora, J.P.5
Janssens, C.6
Reddehase, M.J.7
Lejeune, J.8
Boon, T.9
-
10
-
-
0030800823
-
A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma
-
Mandruzzato, S., F. Brasseur, G. Andry, T. Boon, and P. van der Bruggen. 1997. A CASP-8 mutation recognized by cytolytic T lymphocytes on a human head and neck carcinoma. J. Exp. Med. 186:785-793.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 785-793
-
-
Mandruzzato, S.1
Brasseur, F.2
Andry, G.3
Boon, T.4
Van Der Bruggen, P.5
-
11
-
-
0029669950
-
A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes
-
Robbins, P.F., M. El-Gamil, Y.F. Li, Y. Kawakami, D. Loftus, E. Appella, and S.A. Rosenberg. 1996. A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes. J. Exp. Med. 183:1185-1192.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 1185-1192
-
-
Robbins, P.F.1
El-Gamil, M.2
Li, Y.F.3
Kawakami, Y.4
Loftus, D.5
Appella, E.6
Rosenberg, S.A.7
-
12
-
-
0025764841
-
The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice
-
Van den Eynde, B., B. Lethe, A. Van Pel, E. De Plaen, and T. Boon. 1991. The gene coding for a major tumor rejection antigen of tumor P815 is identical to the normal gene of syngeneic DBA/2 mice. J. Exp. Med. 173:1373-1384.
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1373-1384
-
-
Van Den Eynde, B.1
Lethe, B.2
Van Pel, A.3
De Plaen, E.4
Boon, T.5
-
13
-
-
0035817322
-
Point mutation in essential genes with loss or mutation of the second allele: Relevance to the retention of tumor-specific antigens
-
Beck-Engeser, G.B., P.A. Monach, D. Mumberg, F. Yang, S. Wanderling, K. Schreiber, R. Espinosa III, M.M. Le Beau, S.C. Meredith, and H. Schreiber. 2001. Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens. J. Exp. Med. 194:285-300.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 285-300
-
-
Beck-Engeser, G.B.1
Monach, P.A.2
Mumberg, D.3
Yang, F.4
Wanderling, S.5
Schreiber, K.6
Espinosa III, R.7
Le Beau, M.M.8
Meredith, S.C.9
Schreiber, H.10
-
14
-
-
0029924107
-
Human tumor antigens recognized by T lymphocytes
-
Boon, T., and P. van der Bruggen. 1996. Human tumor antigens recognized by T lymphocytes. J. Exp. Med. 183:725-729.
-
(1996)
J. Exp. Med.
, vol.183
, pp. 725-729
-
-
Boon, T.1
Van Der Bruggen, P.2
-
15
-
-
0028298224
-
Cancer antigens: Immune recognition of self and altered self
-
Houghton, A.N. 1994. Cancer antigens: immune recognition of self and altered self. J. Exp. Med. 180:1-4.
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1-4
-
-
Houghton, A.N.1
-
17
-
-
0038725685
-
Negative selection-clearing out the bad apples from the T-cell repertoire
-
Palmer, E. 2003. Negative selection-clearing out the bad apples from the T-cell repertoire. Nat. Rev. Immunol. 3:383-391.
-
(2003)
Nat. Rev. Immunol.
, vol.3
, pp. 383-391
-
-
Palmer, E.1
-
18
-
-
0033198562
-
The makings of a tumor rejection antigen
-
Gilboa, E. 1999. The makings of a tumor rejection antigen. Immunity. 11:263-270.
-
(1999)
Immunity
, vol.11
, pp. 263-270
-
-
Gilboa, E.1
-
19
-
-
0024814687
-
Model predicting survival in stage I melanoma based on tumor progression
-
Clark, W.H., Jr., D.E. Elder, D.T. Guerry, L.E. Braitman, B.J. Trock, D. Schultz, M. Synnestvedt, and A.C. Halpern. 1989. Model predicting survival in stage I melanoma based on tumor progression. J. Natl. Cancer Inst. 81:1893-1904.
-
(1989)
J. Natl. Cancer Inst.
, vol.81
, pp. 1893-1904
-
-
Clark Jr., W.H.1
Elder, D.E.2
Guerry, D.T.3
Braitman, L.E.4
Trock, B.J.5
Schultz, D.6
Synnestvedt, M.7
Halpern, A.C.8
-
20
-
-
0029925375
-
Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma
-
Clemente, C.G., M.C. Mihm Jr., R. Bufalino, S. Zurrida, P. Collini, and N. Cascinelli. 1996. Prognostic value of tumor infiltrating lymphocytes in the vertical growth phase of primary cutaneous melanoma. Cancer. 77:1303-1310.
-
(1996)
Cancer
, vol.77
, pp. 1303-1310
-
-
Clemente, C.G.1
Mihm Jr., M.C.2
Bufalino, R.3
Zurrida, S.4
Collini, P.5
Cascinelli, N.6
-
21
-
-
0037448353
-
Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
-
Zhang, L., J.R. Conejo-Garcia, D. Katsaros, P.A. Gimotty, M. Massobrio, G. Regnani, A. Makrigiannakis, H. Gray, K. Schlienger, M.N. Liebman, et al. 2003. Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer. N. Engl. J. Med. 348:203-213.
-
(2003)
N. Engl. J. Med.
, vol.348
, pp. 203-213
-
-
Zhang, L.1
Conejo-Garcia, J.R.2
Katsaros, D.3
Gimotty, P.A.4
Massobrio, M.5
Regnani, G.6
Makrigiannakis, A.7
Gray, H.8
Schlienger, K.9
Liebman, M.N.10
-
22
-
-
4644237613
-
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
-
Curiel, T.J., G. Coukos, L. Zou, X. Alvarez, P. Cheng, P. Mottram, M. Evdemon-Hogan, J.R. Conejo-Garcia, L. Zhang, M. Burow, et al. 2004. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 10:942-949.
-
(2004)
Nat. Med.
, vol.10
, pp. 942-949
-
-
Curiel, T.J.1
Coukos, G.2
Zou, L.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
Evdemon-Hogan, M.7
Conejo-Garcia, J.R.8
Zhang, L.9
Burow, M.10
-
23
-
-
0020688264
-
Concomitant tumor immunity and the resistance to a second tumor challenge
-
Gorelik, E. 1983. Concomitant tumor immunity and the resistance to a second tumor challenge. Adv. Cancer Res. 39:71-120.
-
(1983)
Adv. Cancer Res.
, vol.39
, pp. 71-120
-
-
Gorelik, E.1
-
24
-
-
4644342928
-
Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells
-
Turk, M.J., J.A. Guevara-Patino, G.A. Rizzuto, M.E. Engelhorn, and A.N. Houghton. 2004. Concomitant tumor immunity to a poorly immunogenic melanoma is prevented by regulatory T cells. J. Exp. Med. 200:771-782.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 771-782
-
-
Turk, M.J.1
Guevara-Patino, J.A.2
Rizzuto, G.A.3
Engelhorn, M.E.4
Houghton, A.N.5
-
25
-
-
0025355117
-
Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen
-
Perdrizet, G.A., S.R. Ross, H.J. Stauss, S. Singh, H. Koeppen, and H. Schreiber. 1990. Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen. J. Exp. Med. 171:1205-1220.
-
(1990)
J. Exp. Med.
, vol.171
, pp. 1205-1220
-
-
Perdrizet, G.A.1
Ross, S.R.2
Stauss, H.J.3
Singh, S.4
Koeppen, H.5
Schreiber, H.6
-
26
-
-
0027453988
-
Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma
-
Nakagomi, H., M. Petersson, I. Magnusson, C. Juhlin, M. Matsuda, H. Mellstedt, J.L. Taupin, E. Vivier, P. Anderson, and R. Kiessling. 1993. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res. 53:5610-5612.
-
(1993)
Cancer Res.
, vol.53
, pp. 5610-5612
-
-
Nakagomi, H.1
Petersson, M.2
Magnusson, I.3
Juhlin, C.4
Matsuda, M.5
Mellstedt, H.6
Taupin, J.L.7
Vivier, E.8
Anderson, P.9
Kiessling, R.10
-
27
-
-
0026547421
-
Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells
-
Singh, S., S.R. Ross, M. Acena, D.A. Rowley, and H. Schreiber. 1992. Stroma is critical for preventing or permitting immunological destruction of antigenic cancer cells. J. Exp. Med. 175:139-146.
-
(1992)
J. Exp. Med.
, vol.175
, pp. 139-146
-
-
Singh, S.1
Ross, S.R.2
Acena, M.3
Rowley, D.A.4
Schreiber, H.5
-
28
-
-
0036911269
-
Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells
-
Spiotto, M.T., P. Yu, D.A. Rowley, M.I. Nishimura, S.C. Meredith, T.F. Gajewski, Y.X. Fu, and H. Schreiber. 2002. Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells. Immunity. 17:737-747.
-
(2002)
Immunity
, vol.17
, pp. 737-747
-
-
Spiotto, M.T.1
Yu, P.2
Rowley, D.A.3
Nishimura, M.I.4
Meredith, S.C.5
Gajewski, T.F.6
Fu, Y.X.7
Schreiber, H.8
-
29
-
-
0021997185
-
Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease
-
Sakaguchi, S., K. Fukuma, K. Kuribayashi, and T. Masuda. 1985. Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune disease. J. Exp. Med. 161:72-87.
-
(1985)
J. Exp. Med.
, vol.161
, pp. 72-87
-
-
Sakaguchi, S.1
Fukuma, K.2
Kuribayashi, K.3
Masuda, T.4
-
30
-
-
0023710685
-
Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. I. Requirement of Lyt-1 dull L3T4 bright normal T cells for the induction of thyroiditis
-
Sugihara, S., Y. Izumi, T. Yoshioka, H. Yagi, T. Tsujimura, O. Tarutani, Y. Kohno, S. Murakami, T. Hamaoka, and H. Fujiwara. 1988. Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. I. Requirement of Lyt-1 dull L3T4 bright normal T cells for the induction of thyroiditis. J. Immunol. 141:105-113.
-
(1988)
J. Immunol.
, vol.141
, pp. 105-113
-
-
Sugihara, S.1
Izumi, Y.2
Yoshioka, T.3
Yagi, H.4
Tsujimura, T.5
Tarutani, O.6
Kohno, Y.7
Murakami, S.8
Hamaoka, T.9
Fujiwara, H.10
-
32
-
-
2242423605
-
CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity
-
Belkaid, Y., C.A. Piccirillo, S. Mendez, E.M. Shevach, and D.L. Sacks. 2002. CD4+CD25+ regulatory T cells control Leishmania major persistence and immunity. Nature. 420:502-507.
-
(2002)
Nature
, vol.420
, pp. 502-507
-
-
Belkaid, Y.1
Piccirillo, C.A.2
Mendez, S.3
Shevach, E.M.4
Sacks, D.L.5
-
33
-
-
2442484053
-
Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses
-
Sakaguchi, S. 2004. Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses. Annu. Rev. Immunol. 22:531-562.
-
(2004)
Annu. Rev. Immunol.
, vol.22
, pp. 531-562
-
-
Sakaguchi, S.1
-
34
-
-
0036597371
-
CD4+ CD25+ suppressor T cells: More questions than answers
-
Shevach, E.M. 2002. CD4+ CD25+ suppressor T cells: more questions than answers. Nat. Rev. Immunol. 2:389-400.
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 389-400
-
-
Shevach, E.M.1
-
35
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
Maloy, K.J., and F. Powrie. 2001. Regulatory T cells in the control of immune pathology. Nat. Immunol. 2:816-822.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
36
-
-
0018906201
-
T-cell-mediated suppression of antitumor immunity. An explanation for progressive growth of an immunogenic tumor
-
Berendt, M.J., and R.J. North. 1980. T-cell-mediated suppression of antitumor immunity. An explanation for progressive growth of an immunogenic tumor. J. Exp. Med. 151:69-80.
-
(1980)
J. Exp. Med.
, vol.151
, pp. 69-80
-
-
Berendt, M.J.1
North, R.J.2
-
37
-
-
0021275482
-
Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity
-
Bursuker, I., and R.J. North. 1984. Generation and decay of the immune response to a progressive fibrosarcoma. II. Failure to demonstrate postexcision immunity after the onset of T cell-mediated suppression of immunity. J. Exp. Med. 159:1312-1321.
-
(1984)
J. Exp. Med.
, vol.159
, pp. 1312-1321
-
-
Bursuker, I.1
North, R.J.2
-
38
-
-
0024255820
-
Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell- Mediated immunity
-
Awwad, M., and R.J. North. 1988. Immunologically mediated regression of a murine lymphoma after treatment with anti-L3T4 antibody. A consequence of removing L3T4+ suppressor T cells from a host generating predominantly Lyt-2+ T cell- mediated immunity. J. Exp. Med. 168:2193-2206.
-
(1988)
J. Exp. Med.
, vol.168
, pp. 2193-2206
-
-
Awwad, M.1
North, R.J.2
-
39
-
-
0035903324
-
Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
-
Sutmuller, R.P., L.M. van Duivenvoorde, A. van Elsas, T.N. Schumacher, M.E. Wildenberg, J.P. Allison, R.E. Toes, R. Offringa, and C.J. Melief. 2001. Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J. Exp. Med. 194:823-832.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 823-832
-
-
Sutmuller, R.P.1
Van Duivenvoorde, L.M.2
Van Elsas, A.3
Schumacher, T.N.4
Wildenberg, M.E.5
Allison, J.P.6
Toes, R.E.7
Offringa, R.8
Melief, C.J.9
-
40
-
-
0035893387
-
Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma
-
Steitz, J., J. Bruck, J. Lenz, J. Knop, and T. Tuting. 2001. Depletion of CD25(+) CD4(+) T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon alpha-induced, CD8(+) T-cell-dependent immune defense of B16 melanoma. Cancer Res. 61:8643-8646.
-
(2001)
Cancer Res.
, vol.61
, pp. 8643-8646
-
-
Steitz, J.1
Bruck, J.2
Lenz, J.3
Knop, J.4
Tuting, T.5
-
41
-
-
0033571105
-
Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
-
Shimizu, J., S. Yamazaki, and S. Sakaguchi. 1999. Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J. Immunol. 163:5211-5218.
-
(1999)
J. Immunol.
, vol.163
, pp. 5211-5218
-
-
Shimizu, J.1
Yamazaki, S.2
Sakaguchi, S.3
-
42
-
-
3242736641
-
Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice
-
Jones, E., M. Dahm-Vicker, A.K. Simon, A. Green, F. Powrie, V. Cerundolo, and A. Gallimore. 2002. Depletion of CD25+ regulatory cells results in suppression of melanoma growth and induction of autoreactivity in mice. Cancer Immun. 2:1.
-
(2002)
Cancer Immun.
, vol.2
, pp. 1
-
-
Jones, E.1
Dahm-Vicker, M.2
Simon, A.K.3
Green, A.4
Powrie, F.5
Cerundolo, V.6
Gallimore, A.7
-
43
-
-
0024383883
-
Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells
-
Ward, P.L., H. Koeppen, T. Hurteau, and H. Schreiber. 1989. Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells. J. Exp. Med. 170:217-232.
-
(1989)
J. Exp. Med.
, vol.170
, pp. 217-232
-
-
Ward, P.L.1
Koeppen, H.2
Hurteau, T.3
Schreiber, H.4
-
44
-
-
0031007143
-
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
-
Melero, I., W.W. Shuford, S.A. Newby, A. Aruffo, J.A. Ledbetter, K.E. Hellstrom, R.S. Mittler, and L. Chen. 1997. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat. Med. 3:682-685.
-
(1997)
Nat. Med.
, vol.3
, pp. 682-685
-
-
Melero, I.1
Shuford, W.W.2
Newby, S.A.3
Aruffo, A.4
Ledbetter, J.A.5
Hellstrom, K.E.6
Mittler, R.S.7
Chen, L.8
-
45
-
-
0019977370
-
Immunoselection of tumor cell variants by mice suppressed with ultraviolet radiation
-
Urban, J.L., J.M. Holland, M.L. Kripke, and H. Schreiber. 1982. Immunoselection of tumor cell variants by mice suppressed with ultraviolet radiation. J. Exp. Med. 156:1025-1041.
-
(1982)
J. Exp. Med.
, vol.156
, pp. 1025-1041
-
-
Urban, J.L.1
Holland, J.M.2
Kripke, M.L.3
Schreiber, H.4
-
46
-
-
0020546609
-
Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression
-
Uyttenhove, C., J. Maryanski, and T. Boon. 1983. Escape of mouse mastocytoma P815 after nearly complete rejection is due to antigen-loss variants rather than immunosuppression. J. Exp. Med. 157:1040-1052.
-
(1983)
J. Exp. Med.
, vol.157
, pp. 1040-1052
-
-
Uyttenhove, C.1
Maryanski, J.2
Boon, T.3
-
47
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri, R., T. Cox, S.A. Yasayko, and F. Ramsdell. 2003. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4:337-342.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
48
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot, J.D., M.A. Gavin, and A.Y. Rudensky. 2003. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4:330-336.
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
49
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori, S., T. Nomura, and S. Sakaguchi. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science. 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
50
-
-
0037460070
-
Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells
-
Yu, P., M.T. Spiotto, Y. Lee, H. Schreiber, and Y.X. Fu. 2003. Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells. J. Exp. Med. 197:985-995.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 985-995
-
-
Yu, P.1
Spiotto, M.T.2
Lee, Y.3
Schreiber, H.4
Fu, Y.X.5
-
51
-
-
0034666095
-
Importance of CD4(+) T helper cell responses in tumor immunity
-
Ossendorp, F., R.E. Toes, R. Offringa, S.H. van der Burg, and C.J. Melief. 2000. Importance of CD4(+) T helper cell responses in tumor immunity. Immunol. Lett. 74:75-79.
-
(2000)
Immunol. Lett.
, vol.74
, pp. 75-79
-
-
Ossendorp, F.1
Toes, R.E.2
Offringa, R.3
Van Der Burg, S.H.4
Melief, C.J.5
-
53
-
-
0033103127
-
CD4 T cells and their role in antitumor immune responses
-
Toes, R.E., F. Ossendorp, R. Offringa, and C.J. Melief. 1999. CD4 T cells and their role in antitumor immune responses. J. Exp. Med. 189:753-756.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 753-756
-
-
Toes, R.E.1
Ossendorp, F.2
Offringa, R.3
Melief, C.J.4
-
54
-
-
0034919646
-
The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity
-
Wang, R.F. 2001. The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunity. Trends Immunol. 22:269-276.
-
(2001)
Trends Immunol.
, vol.22
, pp. 269-276
-
-
Wang, R.F.1
-
55
-
-
0037456367
-
CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes
-
Janssen, E.M., E.E. Lemmens, T. Wolfe, U. Christen, M.G. von Herrath, and S.P. Schoenberger. 2003. CD4+ T cells are required for secondary expansion and memory in CD8+ T lymphocytes. Nature. 421:852-856.
-
(2003)
Nature
, vol.421
, pp. 852-856
-
-
Janssen, E.M.1
Lemmens, E.E.2
Wolfe, T.3
Christen, U.4
Von Herrath, M.G.5
Schoenberger, S.P.6
-
56
-
-
0037432776
-
Defective CD8 T cell memory following acute infection without CD4 T cell help
-
Sun, J.C., and M.J. Bevan. 2003. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science. 300:339-342.
-
(2003)
Science
, vol.300
, pp. 339-342
-
-
Sun, J.C.1
Bevan, M.J.2
-
57
-
-
0037432787
-
Requirement for CD4 T cell help in generating functional CD8 T cell memory
-
Shedlock, D.J., and H. Shen. 2003. Requirement for CD4 T cell help in generating functional CD8 T cell memory. Science. 300:337-339.
-
(2003)
Science
, vol.300
, pp. 337-339
-
-
Shedlock, D.J.1
Shen, H.2
-
58
-
-
0037174674
-
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
-
Dudley, M.E., J.R. Wunderlich, P.F. Robbins, J.C. Yang, P. Hwu, D.J. Schwartzentruber, S.L. Topalian, R. Sherry, N.P. Restifo, A.M. Hubicki, et al. 2002. Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes. Science. 298:850-854.
-
(2002)
Science
, vol.298
, pp. 850-854
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Robbins, P.F.3
Yang, J.C.4
Hwu, P.5
Schwartzentruber, D.J.6
Topalian, S.L.7
Sherry, R.8
Restifo, N.P.9
Hubicki, A.M.10
-
59
-
-
0037013827
-
Identification of a mutated fibronectin as a tumor antigen recognized by CD4+ T cells: Its role in extracellular matrix formation and tumor metastasis
-
Wang, H.Y., J. Zhou, K. Zhu, A.I. Riker, F.M. Marincola, and R.F. Wang. 2002. Identification of a mutated fibronectin as a tumor antigen recognized by CD4+ T cells: its role in extracellular matrix formation and tumor metastasis. J. Exp. Med. 195:1397-1406.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1397-1406
-
-
Wang, H.Y.1
Zhou, J.2
Zhu, K.3
Riker, A.I.4
Marincola, F.M.5
Wang, R.F.6
-
60
-
-
17944364189
-
Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: Comparison of prophylaxis and therapy
-
van Elsas, A., R.P. Sutmuller, A.A. Hurwitz, J. Ziskin, J. Villasenor, J.P. Medema, W.W. Overwijk, N.P. Restifo, C.J. Melief, R. Offringa, and J.P. Allison. 2001. Elucidating the autoimmune and antitumor effector mechanisms of a treatment based on cytotoxic T lymphocyte antigen-4 blockade in combination with a B16 melanoma vaccine: comparison of prophylaxis and therapy. J. Exp. Med. 194:481-489.
-
(2001)
J. Exp. Med.
, vol.194
, pp. 481-489
-
-
Van Elsas, A.1
Sutmuller, R.P.2
Hurwitz, A.A.3
Ziskin, J.4
Villasenor, J.5
Medema, J.P.6
Overwijk, W.W.7
Restifo, N.P.8
Melief, C.J.9
Offringa, R.10
Allison, J.P.11
-
61
-
-
0344153890
-
CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination
-
Casares, N., L. Arribillaga, P. Sarobe, J. Dotor, A. Lopez-Diaz de Cerio, I. Melero, J. Prieto, F. Borras-Cuesta, and J.J. Lasarte. 2003. CD4+/CD25+ regulatory cells inhibit activation of tumor-primed CD4+ T cells with IFN-gamma-dependent antiangiogenic activity, as well as long-lasting tumor immunity elicited by peptide vaccination. J. Immunol. 171:5931-5939.
-
(2003)
J. Immunol.
, vol.171
, pp. 5931-5939
-
-
Casares, N.1
Arribillaga, L.2
Sarobe, P.3
Dotor, J.4
Lopez-Diaz De Cerio, A.5
Melero, I.6
Prieto, J.7
Borras-Cuesta, F.8
Lasarte, J.J.9
-
62
-
-
0036858838
-
Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens
-
Golgher, D., E. Jones, F. Powrie, T. Elliott, and A. Gallimore. 2002. Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens. Eur. J. Immunol. 32:3267-3275.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 3267-3275
-
-
Golgher, D.1
Jones, E.2
Powrie, F.3
Elliott, T.4
Gallimore, A.5
-
63
-
-
0035328683
-
Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
-
Machiels, J.P., R.T. Reilly, L.A. Emens, A.M. Ercolini, R.Y. Lei, D. Weintraub, F.I. Okoye, and E.M. Jaffee. 2001. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage- colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 61:3689-3697.
-
(2001)
Cancer Res.
, vol.61
, pp. 3689-3697
-
-
Machiels, J.P.1
Reilly, R.T.2
Emens, L.A.3
Ercolini, A.M.4
Lei, R.Y.5
Weintraub, D.6
Okoye, F.I.7
Jaffee, E.M.8
-
64
-
-
0346995283
-
Complete regression of experimental solid tumors by combination LEC/chTNT-3 immunotherapy and CD25(+) T-cell depletion
-
Li, J., P. Hu, L.A. Khawli, and A.L. Epstein. 2003. Complete regression of experimental solid tumors by combination LEC/chTNT-3 immunotherapy and CD25(+) T-cell depletion. Cancer Res. 63:8384-8392.
-
(2003)
Cancer Res.
, vol.63
, pp. 8384-8392
-
-
Li, J.1
Hu, P.2
Khawli, L.A.3
Epstein, A.L.4
-
65
-
-
0033168037
-
Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
-
Onizuka, S., I. Tawara, J. Shimizu, S. Sakaguchi, T. Fujita, and E. Nakayama. 1999. Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res. 59:3128-3133.
-
(1999)
Cancer Res.
, vol.59
, pp. 3128-3133
-
-
Onizuka, S.1
Tawara, I.2
Shimizu, J.3
Sakaguchi, S.4
Fujita, T.5
Nakayama, E.6
-
66
-
-
0036670289
-
Sequential involvement of two distinct CD4+ regulatory T cells during the course of transplantable tumor growth and protection from 3-methylcholanthrene- induced tumorigenesis by CD25-depletion
-
Tawara, I., Y. Take, A. Uenaka, Y. Noguchi, and E. Nakayama. 2002. Sequential involvement of two distinct CD4+ regulatory T cells during the course of transplantable tumor growth and protection from 3-methylcholanthrene-induced tumorigenesis by CD25-depletion. Jpn. J. Cancer Res. 93:911-916.
-
(2002)
Jpn. J. Cancer Res.
, vol.93
, pp. 911-916
-
-
Tawara, I.1
Take, Y.2
Uenaka, A.3
Noguchi, Y.4
Nakayama, E.5
-
67
-
-
0035806244
-
Ex vivo isolation and characterization of CD4(+) CD25(+) T cells with regulatory properties from human blood
-
Dieckmann, D., H. Plottner, S. Berchtold, T. Berger, and G. Schuler. 2001. Ex vivo isolation and characterization of CD4(+) CD25(+) T cells with regulatory properties from human blood. J. Exp. Med. 193:1303-1310.
-
(2001)
J. Exp. Med.
, vol.193
, pp. 1303-1310
-
-
Dieckmann, D.1
Plottner, H.2
Berchtold, S.3
Berger, T.4
Schuler, G.5
-
68
-
-
0036721629
-
Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
-
Liyanage, U.K., T.T. Moore, H.G. Joo, Y. Tanaka, V. Herrmann, G. Doherty, J.A. Drebin, S.M. Strasberg, T.J. Eberlein, P.S. Goedegebuure, and D.C. Linehan. 2002. Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma. J. Immunol. 169:2756-2761.
-
(2002)
J. Immunol.
, vol.169
, pp. 2756-2761
-
-
Liyanage, U.K.1
Moore, T.T.2
Joo, H.G.3
Tanaka, Y.4
Herrmann, V.5
Doherty, G.6
Drebin, J.A.7
Strasberg, S.M.8
Eberlein, T.J.9
Goedegebuure, P.S.10
Linehan, D.C.11
-
69
-
-
0035874949
-
Regulatory CD4(+) CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer
-
Woo, E.Y., C.S. Chu, T.J. Goletz, K. Schlienger, H. Yeh, G. Coukos, S.C. Rubin, L.R. Kaiser, and C.H. June. 2001. Regulatory CD4(+) CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer. Cancer Res. 61:4766-4772.
-
(2001)
Cancer Res.
, vol.61
, pp. 4766-4772
-
-
Woo, E.Y.1
Chu, C.S.2
Goletz, T.J.3
Schlienger, K.4
Yeh, H.5
Coukos, G.6
Rubin, S.C.7
Kaiser, L.R.8
June, C.H.9
-
70
-
-
0036569127
-
Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation
-
Woo, E.Y., H. Yeh, C.S. Chu, K. Schlienger, R.G. Carroll, J.L. Riley, L.R. Kaiser, and C.H. June. 2002. Cutting edge: Regulatory T cells from lung cancer patients directly inhibit autologous T cell proliferation. J. Immunol. 168:4272-4276.
-
(2002)
J. Immunol.
, vol.168
, pp. 4272-4276
-
-
Woo, E.Y.1
Yeh, H.2
Chu, C.S.3
Schlienger, K.4
Carroll, R.G.5
Riley, J.L.6
Kaiser, L.R.7
June, C.H.8
-
71
-
-
1642497640
-
Tumor-specific human CD4+ regulatory T cells and their ligands: Implications for immunotherapy
-
Wang, H.Y., D.A. Lee, G. Peng, Z. Guo, Y. Li, Y. Kiniwa, E.M. Shevach, and R.F. Wang. 2004. Tumor-specific human CD4+ regulatory T cells and their ligands: implications for immunotherapy. Immunity. 20:107-118.
-
(2004)
Immunity
, vol.20
, pp. 107-118
-
-
Wang, H.Y.1
Lee, D.A.2
Peng, G.3
Guo, Z.4
Li, Y.5
Kiniwa, Y.6
Shevach, E.M.7
Wang, R.F.8
-
72
-
-
10744227434
-
Priming of naive T cells inside tumors leads to eradication of established tumors
-
Yu, P., Y. Lee, W. Liu, R.K. Chin, J. Wang, Y. Wang, A. Schietinger, M. Philip, H. Schreiber, and Y.X. Fu. 2004. Priming of naive T cells inside tumors leads to eradication of established tumors. Nat. Immunol. 5:141-149.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 141-149
-
-
Yu, P.1
Lee, Y.2
Liu, W.3
Chin, R.K.4
Wang, J.5
Wang, Y.6
Schietinger, A.7
Philip, M.8
Schreiber, H.9
Fu, Y.X.10
-
73
-
-
0035997910
-
Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production
-
Kang, H.S., R.K. Chin, Y. Wang, P. Yu, J. Wang, K.A. Newell, and Y.X. Fu. 2002. Signaling via LTbetaR on the lamina propria stromal cells of the gut is required for IgA production. Nat. Immunol. 3:576-582.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 576-582
-
-
Kang, H.S.1
Chin, R.K.2
Wang, Y.3
Yu, P.4
Wang, J.5
Newell, K.A.6
Fu, Y.X.7
|