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Volumn 2, Issue 1, 2009, Pages 70-76

p75NTR as a therapeutic target for neuropsychiatric diseases

Author keywords

Alzheimer's disease; Depression; Drug discovery; Knockout (KO) mouse; Neurotrophin; p75NTR; Proneurotrophin; Schizophrenia

Indexed keywords

CAFFEINE DERIVATIVE; LM11A 24; NEUROTROPHIN RECEPTOR P75; UNCLASSIFIED DRUG; NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR;

EID: 77449115618     PISSN: 18744672     EISSN: 18744702     Source Type: Journal    
DOI: 10.2174/1874467210902010070     Document Type: Article
Times cited : (26)

References (124)
  • 2
    • 0022389934 scopus 로고
    • Characterization of the human melanoma nerve growth factor receptor
    • Grob, P. M.; Ross, A. H.; Koprowski, H.; Bothwell, M. Characterization of the human melanoma nerve growth factor receptor. J. Biol. Chem. 1985, 260, 8044-8049.
    • (1985) J. Biol. Chem , vol.260 , pp. 8044-8049
    • Grob, P.M.1    Ross, A.H.2    Koprowski, H.3    Bothwell, M.4
  • 3
    • 0015730599 scopus 로고
    • Properties of the beta nerve growth factor receptor of avian dorsal root ganglia
    • Herrup, K.; Shooter, E. M. Properties of the beta nerve growth factor receptor of avian dorsal root ganglia. Proc. Natl. Acad. Sci. USA 1973, 70, 3884-3888.
    • (1973) Proc. Natl. Acad. Sci. USA , vol.70 , pp. 3884-3888
    • Herrup, K.1    Shooter, E.M.2
  • 5
    • 0023133256 scopus 로고
    • Gene transfer and molecular cloning of the rat nerve growth factor receptor
    • Radeke, M. J.; Misko, T. P.; Hsu, C.; Herzenberg, L. A.; Shooter, E. M. Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature 1987, 325, 593-597.
    • (1987) Nature , vol.325 , pp. 593-597
    • Radeke, M.J.1    Misko, T.P.2    Hsu, C.3    Herzenberg, L.A.4    Shooter, E.M.5
  • 7
    • 33750965014 scopus 로고    scopus 로고
    • Estrogen-BDNF interactions: Implications for neurodegenerative diseases
    • Sohrabji, F.; Lewis, D. K. Estrogen-BDNF interactions: implications for neurodegenerative diseases. Front. Neuroendocrinol. 2006, 27, 404-414.
    • (2006) Front. Neuroendocrinol , vol.27 , pp. 404-414
    • Sohrabji, F.1    Lewis, D.K.2
  • 8
    • 33947517574 scopus 로고    scopus 로고
    • Neural network plasticity, BDNF and behavioral interventions in Alzheimer's disease
    • Hubka, P. Neural network plasticity, BDNF and behavioral interventions in Alzheimer's disease. Bratisl. Lek. Listy 2006, 107, 395-401.
    • (2006) Bratisl. Lek. Listy , vol.107 , pp. 395-401
    • Hubka, P.1
  • 9
    • 35448995279 scopus 로고    scopus 로고
    • Neurotrophic factors-a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases?
    • Schulte-Herbruggen, O.; Braun, A.; Rochlitzer, S.; Jockers-Scherubl, M. C.; Hellweg, R. Neurotrophic factors-a tool for therapeutic strategies in neurological, neuropsychiatric and neuroimmunological diseases? Curr. Med. Chem. 2007, 14, 2318-2329.
    • (2007) Curr. Med. Chem , vol.14 , pp. 2318-2329
    • Schulte-Herbruggen, O.1    Braun, A.2    Rochlitzer, S.3    Jockers-Scherubl, M.C.4    Hellweg, R.5
  • 10
    • 34548336779 scopus 로고    scopus 로고
    • New insights into BDNF function in depression and anxiety
    • Martinowich, K.; Manji, H.; Lu, B. New insights into BDNF function in depression and anxiety. Nat. Neurosci. 2007, 10, 1089-1093.
    • (2007) Nat. Neurosci , vol.10 , pp. 1089-1093
    • Martinowich, K.1    Manji, H.2    Lu, B.3
  • 11
    • 34548130153 scopus 로고    scopus 로고
    • Role of BDNF in bipolar and unipolar disorder: Clinical and theoretical implications
    • Post, R. M. Role of BDNF in bipolar and unipolar disorder: clinical and theoretical implications. J. Psychiatr. Res. 2007, 41, 979-990.
    • (2007) J. Psychiatr. Res , vol.41 , pp. 979-990
    • Post, R.M.1
  • 12
    • 4444320149 scopus 로고    scopus 로고
    • Neurotrophic factors and the pathophysiology of schizophrenic psychoses
    • Durany, N.; Thome, J. Neurotrophic factors and the pathophysiology of schizophrenic psychoses. Eur. Psychiatry 2004, 19, 326-337.
    • (2004) Eur. Psychiatry , vol.19 , pp. 326-337
    • Durany, N.1    Thome, J.2
  • 15
    • 2442434770 scopus 로고    scopus 로고
    • Structure of nerve growth factor complexed with the shared neurotrophin receptor p75
    • He, X. L.; Garcia, K. C. Structure of nerve growth factor complexed with the shared neurotrophin receptor p75. Science 2004, 304, 870-875.
    • (2004) Science , vol.304 , pp. 870-875
    • He, X.L.1    Garcia, K.C.2
  • 16
    • 0029914496 scopus 로고    scopus 로고
    • O-linked oligosaccharide on the 75-kDa neurotrophin receptor
    • Chapman, B. S.; Eckart, M. R.; Kaufman, S. E.; Lapointe, G. R. O-linked oligosaccharide on the 75-kDa neurotrophin receptor. J. Neurochem. 1996, 66, 1707-1716.
    • (1996) J. Neurochem , vol.66 , pp. 1707-1716
    • Chapman, B.S.1    Eckart, M.R.2    Kaufman, S.E.3    Lapointe, G.R.4
  • 17
    • 0034730639 scopus 로고    scopus 로고
    • Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death
    • Coulson, E. J.; Reid, K.; Baca, M.; Shipham, K. A.; Hulett, S. M.; Kilpatrick, T. J.; Bartlett, P. F. Chopper, a new death domain of the p75 neurotrophin receptor that mediates rapid neuronal cell death. J. Biol. Chem. 2000, 275, 30537-30545.
    • (2000) J. Biol. Chem , vol.275 , pp. 30537-30545
    • Coulson, E.J.1    Reid, K.2    Baca, M.3    Shipham, K.A.4    Hulett, S.M.5    Kilpatrick, T.J.6    Bartlett, P.F.7
  • 18
    • 0030851905 scopus 로고    scopus 로고
    • NMR structure of the death domain of the p75 neurotrophin receptor
    • Liepinsh, E.; Ilag, L. L.; Otting, G.; Ibanez, C. F. NMR structure of the death domain of the p75 neurotrophin receptor. EMBO J. 1997, 16, 4999-5005.
    • (1997) EMBO J , vol.16 , pp. 4999-5005
    • Liepinsh, E.1    Ilag, L.L.2    Otting, G.3    Ibanez, C.F.4
  • 19
    • 0347480307 scopus 로고    scopus 로고
    • The role of neurotransmission and the Chopper domain in p75 neurotrophin receptor death signaling
    • Coulson, E. J.; Reid, K.; Shipham, K. M.; Morley, S.; Kilpatrick, T. J.; Bartlett, P. F. The role of neurotransmission and the Chopper domain in p75 neurotrophin receptor death signaling. Prog. Brain Res. 2004, 146, 41-62.
    • (2004) Prog. Brain Res , vol.146 , pp. 41-62
    • Coulson, E.J.1    Reid, K.2    Shipham, K.M.3    Morley, S.4    Kilpatrick, T.J.5    Bartlett, P.F.6
  • 20
    • 0028108788 scopus 로고
    • Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor
    • Dobrowsky, R. T.; Werner, M. H.; Castellino, A. M.; Chao, M. V.; Hannun, Y. A. Activation of the sphingomyelin cycle through the low-affinity neurotrophin receptor. Science 1994, 265, 1596-1599.
    • (1994) Science , vol.265 , pp. 1596-1599
    • Dobrowsky, R.T.1    Werner, M.H.2    Castellino, A.M.3    Chao, M.V.4    Hannun, Y.A.5
  • 22
    • 0035933783 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway
    • Roux, P. P.; Bhakar, A. L.; Kennedy, T. E.; Barker, P. A. The p75 neurotrophin receptor activates Akt (protein kinase B) through a phosphatidylinositol 3-kinase-dependent pathway. J. Biol. Chem. 2001, 276, 23097-23104.
    • (2001) J. Biol. Chem , vol.276 , pp. 23097-23104
    • Roux, P.P.1    Bhakar, A.L.2    Kennedy, T.E.3    Barker, P.A.4
  • 23
    • 0034279150 scopus 로고    scopus 로고
    • Neurotrophins induce death of hippocampal neurons via the p75 receptor
    • Friedman, W. J. Neurotrophins induce death of hippocampal neurons via the p75 receptor. J. Neurosci. 2000, 20, 6340-6346.
    • (2000) J. Neurosci , vol.20 , pp. 6340-6346
    • Friedman, W.J.1
  • 24
    • 2442463255 scopus 로고    scopus 로고
    • p75NTR is positively promiscuous: Novel partners and new insights
    • Barker, P. A. p75NTR is positively promiscuous: novel partners and new insights. Neuron 2004, 42, 529-533.
    • (2004) Neuron , vol.42 , pp. 529-533
    • Barker, P.A.1
  • 25
    • 0025774207 scopus 로고
    • High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor
    • Hempstead, B. L.; Martin-Zanca, D.; Kaplan, D. R.; Parada, L. F.; Chao, M. V. High-affinity NGF binding requires coexpression of the trk protooncogene and the low-affinity NGF receptor. Nature 1991, 350, 678-683.
    • (1991) Nature , vol.350 , pp. 678-683
    • Hempstead, B.L.1    Martin-Zanca, D.2    Kaplan, D.R.3    Parada, L.F.4    Chao, M.V.5
  • 26
    • 0027526580 scopus 로고
    • HSV-1 vector-mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines highaffinity NGF binding
    • Battleman, D. S.; Geller, A. I.; Chao, M. V. HSV-1 vector-mediated gene transfer of the human nerve growth factor receptor p75hNGFR defines highaffinity NGF binding. J. Neurosci. 1993, 13, 941-951.
    • (1993) J. Neurosci , vol.13 , pp. 941-951
    • Battleman, D.S.1    Geller, A.I.2    Chao, M.V.3
  • 27
    • 0027183950 scopus 로고
    • Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness
    • Benedetti, M.; Levi, A.; Chao, M. V. Differential expression of nerve growth factor receptors leads to altered binding affinity and neurotrophin responsiveness. Proc. Natl. Acad. Sci. USA 1993, 90, 7859-7863.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 7859-7863
    • Benedetti, M.1    Levi, A.2    Chao, M.V.3
  • 28
    • 0028217645 scopus 로고
    • High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors
    • Mahadeo, D.; Kaplan, L.; Chao, M. V.; Hempstead, B. L. High affinity nerve growth factor binding displays a faster rate of association than p140trk binding. Implications for multi-subunit polypeptide receptors. J. Biol. Chem. 1994, 269, 6884-6891.
    • (1994) J. Biol. Chem , vol.269 , pp. 6884-6891
    • Mahadeo, D.1    Kaplan, L.2    Chao, M.V.3    Hempstead, B.L.4
  • 29
    • 0027939697 scopus 로고
    • The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins
    • Hantzopoulos, P. A.; Suri, C.; Glass, D. J.; Goldfarb, M. P.; Yancopoulos, G. D. The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins. Neuron 1994, 13, 187-201.
    • (1994) Neuron , vol.13 , pp. 187-201
    • Hantzopoulos, P.A.1    Suri, C.2    Glass, D.J.3    Goldfarb, M.P.4    Yancopoulos, G.D.5
  • 30
    • 0030016335 scopus 로고    scopus 로고
    • p75(NGFR) and TrkA receptors collaborate to rapidly activate a p75(NGFR)-associated protein kinase
    • Canossa, M.; Twiss, J. L.; Verity, A. N.; Shooter, E. M. p75(NGFR) and TrkA receptors collaborate to rapidly activate a p75(NGFR)-associated protein kinase. EMBO J. 1996, 15, 3369-3376.
    • (1996) EMBO J , vol.15 , pp. 3369-3376
    • Canossa, M.1    Twiss, J.L.2    Verity, A.N.3    Shooter, E.M.4
  • 33
    • 0030723983 scopus 로고    scopus 로고
    • Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease
    • Yaar, M.; Zhai, S.; Pilch, P. F.; Doyle, S. M.; Eisenhauer, P. B.; Fine, R. E.; Gilchrest, B. A. Binding of beta-amyloid to the p75 neurotrophin receptor induces apoptosis. A possible mechanism for Alzheimer's disease. J. Clin. Invest. 1997, 100, 2333-2340.
    • (1997) J. Clin. Invest , vol.100 , pp. 2333-2340
    • Yaar, M.1    Zhai, S.2    Pilch, P.F.3    Doyle, S.M.4    Eisenhauer, P.B.5    Fine, R.E.6    Gilchrest, B.A.7
  • 35
    • 0032535485 scopus 로고    scopus 로고
    • Lowaffinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus
    • Tuffereau, C.; Benejean, J.; Blondel, D.; Kieffer, B.; Flamand, A. Lowaffinity nerve-growth factor receptor (P75NTR) can serve as a receptor for rabies virus. EMBO J. 1998, 17, 7250-729.
    • (1998) EMBO J , vol.17 , pp. 7250-7729
    • Tuffereau, C.1    Benejean, J.2    Blondel, D.3    Kieffer, B.4    Flamand, A.5
  • 36
    • 37049021996 scopus 로고    scopus 로고
    • The rabies virus glycoprotein receptor p75NTR is not essential for rabies virus infection
    • Tuffereau, C.; Schmidt, K.; Langevin, C.; Lafay, F.; Dechant, G.; Koltzenburg, M. The rabies virus glycoprotein receptor p75NTR is not essential for rabies virus infection. J. Virol. 2007, 81, 13622-30.
    • (2007) J. Virol , vol.81 , pp. 13622-30
    • Tuffereau, C.1    Schmidt, K.2    Langevin, C.3    Lafay, F.4    Dechant, G.5    Koltzenburg, M.6
  • 37
    • 0037038435 scopus 로고    scopus 로고
    • P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp
    • Wang, K. C.; Kim, J. A.; Sivasankaran, R.; Segal, R.; He, Z. P75 interacts with the Nogo receptor as a co-receptor for Nogo, MAG and OMgp. Nature 2002, 420, 74-78.
    • (2002) Nature , vol.420 , pp. 74-78
    • Wang, K.C.1    Kim, J.A.2    Sivasankaran, R.3    Segal, R.4    He, Z.5
  • 39
    • 34347209978 scopus 로고    scopus 로고
    • A cell-biological model of p75NTR signaling
    • Blochl, A.; Blochl, R. A cell-biological model of p75NTR signaling. J. Neurochem. 2007, 102, 289-305.
    • (2007) J. Neurochem , vol.102 , pp. 289-305
    • Blochl, A.1    Blochl, R.2
  • 40
    • 0034803770 scopus 로고    scopus 로고
    • Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system
    • von Schack, D.; Casademunt, E.; Schweigreiter, R.; Meyer, M.; Bibel, M.; Dechant, G. Complete ablation of the neurotrophin receptor p75NTR causes defects both in the nervous and the vascular system. Nat. Neurosci. 2001, 4, 977-978.
    • (2001) Nat. Neurosci , vol.4 , pp. 977-978
    • von Schack, D.1    Casademunt, E.2    Schweigreiter, R.3    Meyer, M.4    Bibel, M.5    Dechant, G.6
  • 41
    • 0026747063 scopus 로고
    • Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system
    • Lee, K. F.; Li, E.; Huber, L. J.; Landis, S. C.; Sharpe, A. H.; Chao, M. V.; Jaenisch, R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 1992, 69, 737-749.
    • (1992) Cell , vol.69 , pp. 737-749
    • Lee, K.F.1    Li, E.2    Huber, L.J.3    Landis, S.C.4    Sharpe, A.H.5    Chao, M.V.6    Jaenisch, R.7
  • 42
    • 0028843735 scopus 로고
    • A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR-I and Fas
    • Chapman, B. S. A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR-I and Fas. FEBS Lett. 1995, 374, 216-220.
    • (1995) FEBS Lett , vol.374 , pp. 216-220
    • Chapman, B.S.1
  • 43
    • 0028946708 scopus 로고
    • Zone mapping of the binding domain of the rat low affinity nerve growth factor receptor by the introduction of novel Nglycosylation sites
    • Baldwin, A. N.; Shooter, E. M. Zone mapping of the binding domain of the rat low affinity nerve growth factor receptor by the introduction of novel Nglycosylation sites. J. Biol. Chem. 1995, 270, 4594-4602.
    • (1995) J. Biol. Chem , vol.270 , pp. 4594-4602
    • Baldwin, A.N.1    Shooter, E.M.2
  • 44
    • 0037020152 scopus 로고    scopus 로고
    • Rabies virus glycoprotein (RVG) is a trimeric ligand for the N-terminal cysteine-rich domain of the mammalian p75 neurotrophin receptor
    • Langevin, C.; Jaaro, H.; Bressanelli, S.; Fainzilber, M.; Tuffereau, C. Rabies virus glycoprotein (RVG) is a trimeric ligand for the N-terminal cysteine-rich domain of the mammalian p75 neurotrophin receptor. J. Biol. Chem. 2002, 277, 37655-37662.
    • (2002) J. Biol. Chem , vol.277 , pp. 37655-37662
    • Langevin, C.1    Jaaro, H.2    Bressanelli, S.3    Fainzilber, M.4    Tuffereau, C.5
  • 45
    • 0038045714 scopus 로고    scopus 로고
    • Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability
    • Kanning, K. C.; Hudson, M.; Amieux, P. S.; Wiley, J. C.; Bothwell, M.; Schecterson, L. C. Proteolytic processing of the p75 neurotrophin receptor and two homologs generates C-terminal fragments with signaling capability. J. Neurosci. 2003, 23, 5425-5436.
    • (2003) J. Neurosci , vol.23 , pp. 5425-5436
    • Kanning, K.C.1    Hudson, M.2    Amieux, P.S.3    Wiley, J.C.4    Bothwell, M.5    Schecterson, L.C.6
  • 47
    • 0038075293 scopus 로고    scopus 로고
    • NRADD, a novel membrane protein with a death domain involved in mediating apoptosis in response to ER stress
    • Wang, X.; Shao, Z.; Zetoune, F. S.; Zeidler, M. G.; Gowrishankar, K.; Vincenz, C. NRADD, a novel membrane protein with a death domain involved in mediating apoptosis in response to ER stress. Cell Death Differ. 2003, 10, 580-591.
    • (2003) Cell Death Differ , vol.10 , pp. 580-591
    • Wang, X.1    Shao, Z.2    Zetoune, F.S.3    Zeidler, M.G.4    Gowrishankar, K.5    Vincenz, C.6
  • 48
    • 8644280515 scopus 로고    scopus 로고
    • Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder
    • Murray, E.; Malley, S. E.; Qiao, L. Y.; Hu, V. Y.; Vizzard, M. A. Cyclophosphamide induced cystitis alters neurotrophin and receptor tyrosine kinase expression in pelvic ganglia and bladder. J. Urol. 2004, 172, 2434-2439.
    • (2004) J. Urol , vol.172 , pp. 2434-2439
    • Murray, E.1    Malley, S.E.2    Qiao, L.Y.3    Hu, V.Y.4    Vizzard, M.A.5
  • 49
    • 0027330994 scopus 로고
    • p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins
    • Davies, A. M.; Lee, K. F.; Jaenisch, R. p75-deficient trigeminal sensory neurons have an altered response to NGF but not to other neurotrophins. Neuron 1993, 11, 565-574.
    • (1993) Neuron , vol.11 , pp. 565-574
    • Davies, A.M.1    Lee, K.F.2    Jaenisch, R.3
  • 50
    • 0028196552 scopus 로고
    • p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF
    • Lee, K. F.; Davies, A. M.; Jaenisch, R. p75-deficient embryonic dorsal root sensory and neonatal sympathetic neurons display a decreased sensitivity to NGF. Development 1994, 120, 1027-1033.
    • (1994) Development , vol.120 , pp. 1027-1033
    • Lee, K.F.1    Davies, A.M.2    Jaenisch, R.3
  • 51
    • 0034667581 scopus 로고    scopus 로고
    • p75 is important for axon growth and schwann cell migration during development
    • Bentley, C. A.; Lee, K. F. p75 is important for axon growth and schwann cell migration during development. J. Neurosci. 2000, 20, 7706-7715.
    • (2000) J. Neurosci , vol.20 , pp. 7706-7715
    • Bentley, C.A.1    Lee, K.F.2
  • 52
  • 53
    • 0030610047 scopus 로고    scopus 로고
    • Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation
    • Yeo, T. T.; Chua-Couzens, J.; Butcher, L. L.; Bredesen, D. E.; Cooper, J. D.; Valletta, J. S.; Mobley, W. C.; Longo, F. M. Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation. J. Neurosci. 1997, 17, 7594-7605.
    • (1997) J. Neurosci , vol.17 , pp. 7594-7605
    • Yeo, T.T.1    Chua-Couzens, J.2    Butcher, L.L.3    Bredesen, D.E.4    Cooper, J.D.5    Valletta, J.S.6    Mobley, W.C.7    Longo, F.M.8
  • 54
    • 0036550661 scopus 로고    scopus 로고
    • Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons
    • Naumann, T.; Casademunt, E.; Hollerbach, E.; Hofmann, J.; Dechant, G.; Frotscher, M.; Barde, Y. A. Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons. J. Neurosci. 2002, 22, 2409-2418.
    • (2002) J. Neurosci , vol.22 , pp. 2409-2418
    • Naumann, T.1    Casademunt, E.2    Hollerbach, E.3    Hofmann, J.4    Dechant, G.5    Frotscher, M.6    Barde, Y.A.7
  • 55
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji, S. X.; Majdan, M.; Pozniak, C. D.; Belliveau, D. J.; Aloyz, R.; Kohn, J.; Causing, C. G.; Miller, F. D. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J. Cell Biol. 1998, 140, 911-923.
    • (1998) J. Cell Biol , vol.140 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 56
    • 0032968762 scopus 로고    scopus 로고
    • Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord
    • Frade, J. M.; Barde, Y. A. Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 1999, 126, 683-690.
    • (1999) Development , vol.126 , pp. 683-690
    • Frade, J.M.1    Barde, Y.A.2
  • 57
    • 0031982883 scopus 로고    scopus 로고
    • Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor
    • Ferri, C. C.; Moore, F. A.; Bisby, M. A. Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor. J. Neurobiol. 1998, 34, 1-9.
    • (1998) J. Neurobiol , vol.34 , pp. 1-9
    • Ferri, C.C.1    Moore, F.A.2    Bisby, M.A.3
  • 58
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • Troy, C. M.; Friedman, J. E.; Friedman, W. J. Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases. J. Biol. Chem. 2002, 277, 34295-34302.
    • (2002) J. Biol. Chem , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 59
    • 27344442733 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons
    • Zagrebelsky, M.; Holz, A.; Dechant, G.; Barde, Y. A.; Bonhoeffer, T.; Korte, M. The p75 neurotrophin receptor negatively modulates dendrite complexity and spine density in hippocampal neurons. J. Neurosci. 2005, 25, 9989-9999.
    • (2005) J. Neurosci , vol.25 , pp. 9989-9999
    • Zagrebelsky, M.1    Holz, A.2    Dechant, G.3    Barde, Y.A.4    Bonhoeffer, T.5    Korte, M.6
  • 60
    • 18844402387 scopus 로고    scopus 로고
    • The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus
    • Rosch, H.; Schweigreiter, R.; Bonhoeffer, T.; Barde, Y. A.; Korte, M. The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus. Proc. Natl. Acad. Sci. USA 2005, 102, 7362-7367.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 7362-7367
    • Rosch, H.1    Schweigreiter, R.2    Bonhoeffer, T.3    Barde, Y.A.4    Korte, M.5
  • 62
    • 33745615379 scopus 로고    scopus 로고
    • Progressive hearing loss in mice carrying a mutation in the p75 gene
    • Sato, T.; Doi, K.; Taniguchi, M.; Yamashita, T.; Kubo, T.; Tohyama, M. Progressive hearing loss in mice carrying a mutation in the p75 gene. Brain Res. 2006, 1091, 224-234.
    • (2006) Brain Res , vol.1091 , pp. 224-234
    • Sato, T.1    Doi, K.2    Taniguchi, M.3    Yamashita, T.4    Kubo, T.5    Tohyama, M.6
  • 63
    • 34248361975 scopus 로고    scopus 로고
    • p75 neurotrophin receptor expression defines a population of BDNFresponsive neurogenic precursor cells
    • Young, K. M.; Merson, T. D.; Sotthibundhu, A.; Coulson, E. J.; Bartlett, P. F. p75 neurotrophin receptor expression defines a population of BDNFresponsive neurogenic precursor cells. J. Neurosci. 2007, 27, 5146-5155.
    • (2007) J. Neurosci , vol.27 , pp. 5146-5155
    • Young, K.M.1    Merson, T.D.2    Sotthibundhu, A.3    Coulson, E.J.4    Bartlett, P.F.5
  • 64
    • 0033080789 scopus 로고    scopus 로고
    • Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75
    • Peterson, D. A.; Dickinson-Anson, H. A.; Leppert, J. T.; Lee, K. F.; Gage, F. H. Central neuronal loss and behavioral impairment in mice lacking neurotrophin receptor p75. J. Comp. Neurol. 1999, 404, 1-20.
    • (1999) J. Comp. Neurol , vol.404 , pp. 1-20
    • Peterson, D.A.1    Dickinson-Anson, H.A.2    Leppert, J.T.3    Lee, K.F.4    Gage, F.H.5
  • 65
    • 0033358870 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo
    • Brennan, C.; Rivas-Plata, K.; Landis, S. C. The p75 neurotrophin receptor influences NT-3 responsiveness of sympathetic neurons in vivo. Nat. Neurosci. 1999, 2, 699-705.
    • (1999) Nat. Neurosci , vol.2 , pp. 699-705
    • Brennan, C.1    Rivas-Plata, K.2    Landis, S.C.3
  • 66
    • 3242740072 scopus 로고    scopus 로고
    • Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice
    • Wright, J. W.; Alt, J. A.; Turner, G. D.; Krueger, J. M. Differences in spatial learning comparing transgenic p75 knockout, New Zealand Black, C57BL/6, and Swiss Webster mice. Behav. Brain Res. 2004, 153, 453-458.
    • (2004) Behav. Brain Res , vol.153 , pp. 453-458
    • Wright, J.W.1    Alt, J.A.2    Turner, G.D.3    Krueger, J.M.4
  • 67
    • 1842405438 scopus 로고    scopus 로고
    • Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75
    • Peterson, D. A.; Leppert, J. T.; Lee, K. F.; Gage, F. H. Basal forebrain neuronal loss in mice lacking neurotrophin receptor p75. Science 1997, 277, 837-839.
    • (1997) Science , vol.277 , pp. 837-839
    • Peterson, D.A.1    Leppert, J.T.2    Lee, K.F.3    Gage, F.H.4
  • 68
    • 33747051514 scopus 로고    scopus 로고
    • Interaction of survival and death signaling in basal forebrain neurons: Roles of neurotrophins and proneurotrophins
    • Volosin, M.; Song, W.; Almeida, R. D.; Kaplan, D. R.; Hempstead, B. L.; Friedman, W. J. Interaction of survival and death signaling in basal forebrain neurons: roles of neurotrophins and proneurotrophins. J. Neurosci. 2006, 26, 7756-7766.
    • (2006) J. Neurosci , vol.26 , pp. 7756-7766
    • Volosin, M.1    Song, W.2    Almeida, R.D.3    Kaplan, D.R.4    Hempstead, B.L.5    Friedman, W.J.6
  • 71
    • 0033230625 scopus 로고    scopus 로고
    • Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth
    • Yamashita, T.; Tucker, K. L.; Barde, Y. A. Neurotrophin binding to the p75 receptor modulates Rho activity and axonal outgrowth. Neuron 1999, 24, 585-593.
    • (1999) Neuron , vol.24 , pp. 585-593
    • Yamashita, T.1    Tucker, K.L.2    Barde, Y.A.3
  • 72
    • 0031045405 scopus 로고    scopus 로고
    • Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75
    • Bergmann, I.; Priestley, J. V.; McMahon, S. B.; Brocker, E. B.; Toyka, K. V.; Koltzenburg, M. Analysis of cutaneous sensory neurons in transgenic mice lacking the low affinity neurotrophin receptor p75. Eur. J. Neurosci. 1997, 9, 18-28.
    • (1997) Eur. J. Neurosci , vol.9 , pp. 18-28
    • Bergmann, I.1    Priestley, J.V.2    McMahon, S.B.3    Brocker, E.B.4    Toyka, K.V.5    Koltzenburg, M.6
  • 73
    • 13244288014 scopus 로고    scopus 로고
    • Deafferentation and neurotrophinmediated intraspinal sprouting: A central role for the p75 neurotrophin receptor
    • Scott, A. L.; Borisoff, J. F.; Ramer, M. S. Deafferentation and neurotrophinmediated intraspinal sprouting: a central role for the p75 neurotrophin receptor. Eur. J. Neurosci. 2005, 21, 81-92.
    • (2005) Eur. J. Neurosci , vol.21 , pp. 81-92
    • Scott, A.L.1    Borisoff, J.F.2    Ramer, M.S.3
  • 75
    • 0019972810 scopus 로고
    • The cholinergic hypothesis of geriatric memory dysfunction
    • Bartus, R. T.; Dean, R. L., 3rd; Beer, B.; Lippa, A. S. The cholinergic hypothesis of geriatric memory dysfunction. Science 1982, 217, 408-414.
    • (1982) Science , vol.217 , pp. 408-414
    • Bartus, R.T.1    Dean 3rd, R.L.2    Beer, B.3    Lippa, A.S.4
  • 76
    • 0020686674 scopus 로고
    • Alzheimer's disease: A disorder of cortical cholinergic innervation
    • Coyle, J. T.; Price, D. L.; DeLong, M. R. Alzheimer's disease: a disorder of cortical cholinergic innervation. Science 1983, 219, 1184-1190.
    • (1983) Science , vol.219 , pp. 1184-1190
    • Coyle, J.T.1    Price, D.L.2    Delong, M.R.3
  • 77
    • 0033018477 scopus 로고    scopus 로고
    • Acetylcholine in mind: A neurotransmitter correlate of consciousness?
    • Perry, E.; Walker, M.; Grace, J.; Perry, R. Acetylcholine in mind: a neurotransmitter correlate of consciousness? Trends Neurosci. 1999, 22, 273-280.
    • (1999) Trends Neurosci , vol.22 , pp. 273-280
    • Perry, E.1    Walker, M.2    Grace, J.3    Perry, R.4
  • 78
    • 0029829495 scopus 로고    scopus 로고
    • Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice
    • Van der Zee, C. E.; Ross, G. M.; Riopelle, R. J.; Hagg, T. Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice. Science 1996, 274, 1729-1732.
    • (1996) Science , vol.274 , pp. 1729-1732
    • van der Zee, C.E.1    Ross, G.M.2    Riopelle, R.J.3    Hagg, T.4
  • 79
    • 0037174618 scopus 로고    scopus 로고
    • Alzheimer's disease is a synaptic failure
    • Selkoe, D. J. Alzheimer's disease is a synaptic failure. Science 2002, 298, 789-791.
    • (2002) Science , vol.298 , pp. 789-791
    • Selkoe, D.J.1
  • 80
    • 0034641936 scopus 로고    scopus 로고
    • Apoptosis in the nervous system
    • Yuan, J.; Yankner, B. A. Apoptosis in the nervous system. Nature 2000, 407, 802-809.
    • (2000) Nature , vol.407 , pp. 802-809
    • Yuan, J.1    Yankner, B.A.2
  • 81
    • 0037551741 scopus 로고    scopus 로고
    • Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
    • Caughey, B.; Lansbury, P. T. Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu. Rev. Neurosci. 2003, 26, 267-298.
    • (2003) Annu. Rev. Neurosci , vol.26 , pp. 267-298
    • Caughey, B.1    Lansbury, P.T.2
  • 82
    • 0034848604 scopus 로고    scopus 로고
    • The precursor pronerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
    • Fahnestock, M.; Michalski, B.; Xu, B.; Coughlin, M. D. The precursor pronerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol. Cell Neurosci. 2001, 18, 210-220.
    • (2001) Mol. Cell Neurosci , vol.18 , pp. 210-220
    • Fahnestock, M.1    Michalski, B.2    Xu, B.3    Coughlin, M.D.4
  • 83
    • 2942536284 scopus 로고    scopus 로고
    • Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease
    • Peng, S.; Wuu, J.; Mufson, E. J.; Fahnestock, M. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J. Neuropathol. Exp. Neurol. 2004, 63, 641-649.
    • (2004) J. Neuropathol. Exp. Neurol , vol.63 , pp. 641-649
    • Peng, S.1    Wuu, J.2    Mufson, E.J.3    Fahnestock, M.4
  • 84
    • 16844377812 scopus 로고    scopus 로고
    • The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease
    • Counts, S. E.; Mufson, E. J. The role of nerve growth factor receptors in cholinergic basal forebrain degeneration in prodromal Alzheimer disease. J. Neuropathol. Exp. Neurol. 2005, 64, 263-272.
    • (2005) J. Neuropathol. Exp. Neurol , vol.64 , pp. 263-272
    • Counts, S.E.1    Mufson, E.J.2
  • 86
    • 34248178972 scopus 로고    scopus 로고
    • The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease
    • Cuello, A. C.; Bruno, M. A. The failure in NGF maturation and its increased degradation as the probable cause for the vulnerability of cholinergic neurons in Alzheimer's disease. Neurochem. Res. 2007, 32, 1041-1045.
    • (2007) Neurochem. Res , vol.32 , pp. 1041-1045
    • Cuello, A.C.1    Bruno, M.A.2
  • 87
    • 0032534629 scopus 로고    scopus 로고
    • Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells
    • Kuner, P.; Schubenel, R.; Hertel, C. Beta-amyloid binds to p57NTR and activates NFkappaB in human neuroblastoma cells. J. Neurosci. Res. 1998, 54, 798-804.
    • (1998) J. Neurosci. Res , vol.54 , pp. 798-804
    • Kuner, P.1    Schubenel, R.2    Hertel, C.3
  • 89
    • 0037040889 scopus 로고    scopus 로고
    • Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling
    • Yaar, M.; Zhai, S.; Fine, R. E.; Eisenhauer, P. B.; Arble, B. L.; Stewart, K. B.; Gilchrest, B. A. Amyloid beta binds trimers as well as monomers of the 75-kDa neurotrophin receptor and activates receptor signaling. J. Biol. Chem. 2002, 277, 7720-7725.
    • (2002) J. Biol. Chem , vol.277 , pp. 7720-7725
    • Yaar, M.1    Zhai, S.2    Fine, R.E.3    Eisenhauer, P.B.4    Arble, B.L.5    Stewart, K.B.6    Gilchrest, B.A.7
  • 91
    • 27344441077 scopus 로고    scopus 로고
    • The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid
    • Costantini, C.; Della-Bianca, V.; Formaggio, E.; Chiamulera, C.; Montresor, A.; Rossi, F. The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid. Exp. Cell Res. 2005, 311, 126-134.
    • (2005) Exp. Cell Res , vol.311 , pp. 126-134
    • Costantini, C.1    Della-Bianca, V.2    Formaggio, E.3    Chiamulera, C.4    Montresor, A.5    Rossi, F.6
  • 92
    • 0042839610 scopus 로고    scopus 로고
    • Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells
    • Tsukamoto, E.; Hashimoto, Y.; Kanekura, K.; Niikura, T.; Aiso, S.; Nishimoto, I. Characterization of the toxic mechanism triggered by Alzheimer's amyloid-beta peptides via p75 neurotrophin receptor in neuronal hybrid cells. J. Neurosci. Res. 2003, 73, 627-636.
    • (2003) J. Neurosci. Res , vol.73 , pp. 627-636
    • Tsukamoto, E.1    Hashimoto, Y.2    Kanekura, K.3    Niikura, T.4    Aiso, S.5    Nishimoto, I.6
  • 94
    • 24044480687 scopus 로고    scopus 로고
    • Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75
    • Susen, K.; Blochl, A. Low concentrations of aggregated beta-amyloid induce neurite formation via the neurotrophin receptor p75. J. Mol. Med. 2005, 83, 720-735.
    • (2005) J. Mol. Med , vol.83 , pp. 720-735
    • Susen, K.1    Blochl, A.2
  • 95
    • 0036534870 scopus 로고    scopus 로고
    • Role of p75 neurotrophin receptor in the neurotoxicity by betaamyloid peptides and synergistic effect of inflammatory cytokines
    • Perini, G.; Della-Bianca, V.; Politi, V.; Della Valle, G.; Dal-Pra, I.; Rossi, F.; Armato, U. Role of p75 neurotrophin receptor in the neurotoxicity by betaamyloid peptides and synergistic effect of inflammatory cytokines. J. Exp. Med. 2002, 195, 907-918.
    • (2002) J. Exp. Med , vol.195 , pp. 907-918
    • Perini, G.1    Della-Bianca, V.2    Politi, V.3    della Valle, G.4    Dal-Pra, I.5    Rossi, F.6    Armato, U.7
  • 96
    • 3242747480 scopus 로고    scopus 로고
    • The role of BDNF in epilepsy and other diseases of the mature nervous system
    • Binder, D. K. The role of BDNF in epilepsy and other diseases of the mature nervous system. Adv. Exp. Med. Biol. 2004, 548, 34-56.
    • (2004) Adv. Exp. Med. Biol , vol.548 , pp. 34-56
    • Binder, D.K.1
  • 97
    • 3342912013 scopus 로고    scopus 로고
    • A missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75NTR gene is associated with depressive disorder and attempted suicide
    • Kunugi, H.; Hashimoto, R.; Yoshida, M.; Tatsumi, M.; Kamijima, K. A missense polymorphism (S205L) of the low-affinity neurotrophin receptor p75NTR gene is associated with depressive disorder and attempted suicide. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2004, 129, 44-46.
    • (2004) Am. J. Med. Genet. B Neuropsychiatr. Genet , vol.129 , pp. 44-46
    • Kunugi, H.1    Hashimoto, R.2    Yoshida, M.3    Tatsumi, M.4    Kamijima, K.5
  • 99
    • 0034207818 scopus 로고    scopus 로고
    • The neurodevelopmental hypothesis of schizophrenia: Following a trail of evidence from cradle to grave
    • Marenco, S.; Weinberger, D. R. The neurodevelopmental hypothesis of schizophrenia: following a trail of evidence from cradle to grave. Dev. Psychopathol. 2000, 12, 501-527.
    • (2000) Dev. Psychopathol , vol.12 , pp. 501-527
    • Marenco, S.1    Weinberger, D.R.2
  • 100
    • 0029119055 scopus 로고
    • From neuropathology to neurodevelopment
    • Weinberger, D. R. From neuropathology to neurodevelopment. Lancet 1995, 346, 552-557.
    • (1995) Lancet , vol.346 , pp. 552-557
    • Weinberger, D.R.1
  • 102
    • 0023254675 scopus 로고
    • Dopamine receptors and the dopamine hypothesis of schizophrenia
    • Seeman, P. Dopamine receptors and the dopamine hypothesis of schizophrenia. Synapse 1987, 1, 133-152.
    • (1987) Synapse , vol.1 , pp. 133-152
    • Seeman, P.1
  • 104
    • 0018120068 scopus 로고
    • Prestimulus effects on human startle reflex in normals and schizophrenics
    • Braff, D.; Stone, C.; Callaway, E.; Geyer, M.; Glick, I.; Bali, L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology 1978, 15, 339-343.
    • (1978) Psychophysiology , vol.15 , pp. 339-343
    • Braff, D.1    Stone, C.2    Callaway, E.3    Geyer, M.4    Glick, I.5    Bali, L.6
  • 105
    • 0026581360 scopus 로고
    • Gating and habituation of the startle reflex in schizophrenic patients
    • Braff, D. L.; Grillon, C.; Geyer, M. A. Gating and habituation of the startle reflex in schizophrenic patients. Arch. Gen. Psychiatry. 1992, 49, 206-215.
    • (1992) Arch. Gen. Psychiatry , vol.49 , pp. 206-215
    • Braff, D.L.1    Grillon, C.2    Geyer, M.A.3
  • 107
    • 34548033437 scopus 로고    scopus 로고
    • Prepulse inhibition of acoustic startle in Japanese patients with chronic schizophrenia
    • Kunugi, H.; Tanaka, M.; Hori, H.; Hashimoto, R.; Saitoh, O.; Hironaka, N. Prepulse inhibition of acoustic startle in Japanese patients with chronic schizophrenia. Neurosci. Res. 2007, 59, 23-28.
    • (2007) Neurosci. Res , vol.59 , pp. 23-28
    • Kunugi, H.1    Tanaka, M.2    Hori, H.3    Hashimoto, R.4    Saitoh, O.5    Hironaka, N.6
  • 108
    • 0025941802 scopus 로고
    • Nerve growth factor synthesis and nerve growth factor receptor expression in neural development
    • Davies, A. M. Nerve growth factor synthesis and nerve growth factor receptor expression in neural development. Int. Rev. Cytol. 1991, 128, 109-138.
    • (1991) Int. Rev. Cytol , vol.128 , pp. 109-138
    • Davies, A.M.1
  • 109
    • 1842420676 scopus 로고    scopus 로고
    • Altered neurotrophin receptor function in the developing prefrontal cortex leads to adult-onset dopaminergic hyperresponsivity and impaired prepulse inhibition of acoustic startle
    • Rajakumar, N.; Leung, L. S.; Ma, J.; Rajakumar, B.; Rushlow, W. Altered neurotrophin receptor function in the developing prefrontal cortex leads to adult-onset dopaminergic hyperresponsivity and impaired prepulse inhibition of acoustic startle. Biol. Psychiatry 2004, 55, 797-803.
    • (2004) Biol. Psychiatry , vol.55 , pp. 797-803
    • Rajakumar, N.1    Leung, L.S.2    Ma, J.3    Rajakumar, B.4    Rushlow, W.5
  • 111
    • 35448933117 scopus 로고    scopus 로고
    • Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators
    • Gao, X.; Daugherty, R. L.; Tourtellotte, W. G. Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators. Mol. Cell Neurosci. 2007, 36, 501-14.
    • (2007) Mol. Cell Neurosci , vol.36 , pp. 501-514
    • Gao, X.1    Daugherty, R.L.2    Tourtellotte, W.G.3
  • 112
    • 33847337446 scopus 로고    scopus 로고
    • Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia
    • Yamada, K.; Gerber, D. J.; Iwayama, Y.; Ohnishi, T.; Ohba, H.; Toyota, T.; Aruga, J.; Minabe, Y.; Tonegawa, S.; Yoshikawa, T. Genetic analysis of the calcineurin pathway identifies members of the EGR gene family, specifically EGR3, as potential susceptibility candidates in schizophrenia. Proc. Natl. Acad. Sci. USA 2007, 104, 2815-2820.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2815-2820
    • Yamada, K.1    Gerber, D.J.2    Iwayama, Y.3    Ohnishi, T.4    Ohba, H.5    Toyota, T.6    Aruga, J.7    Minabe, Y.8    Tonegawa, S.9    Yoshikawa, T.10
  • 113
    • 13244273471 scopus 로고    scopus 로고
    • MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders
    • Geuze, E.; Vermetten, E.; Bremner, J. D. MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders. Mol. Psychiatry 2005, 10, 160-184.
    • (2005) Mol. Psychiatry , vol.10 , pp. 160-184
    • Geuze, E.1    Vermetten, E.2    Bremner, J.D.3
  • 114
    • 28444491442 scopus 로고    scopus 로고
    • Regional deficits in brain volume in schizophrenia: A meta-analysis of voxel-based morphometry studies
    • Honea, R.; Crow, T. J.; Passingham, D.; Mackay, C. E. Regional deficits in brain volume in schizophrenia: a meta-analysis of voxel-based morphometry studies. Am. J. Psychiatry 2005, 162, 2233-2245.
    • (2005) Am. J. Psychiatry , vol.162 , pp. 2233-2245
    • Honea, R.1    Crow, T.J.2    Passingham, D.3    Mackay, C.E.4
  • 115
    • 33744901419 scopus 로고    scopus 로고
    • Brain volume in first-episode schizophrenia: Systematic review and meta-analysis of magnetic resonance imaging studies
    • Steen, R. G.; Mull, C.; McClure, R.; Hamer, R. M.; Lieberman, J. A. Brain volume in first-episode schizophrenia: systematic review and meta-analysis of magnetic resonance imaging studies. Br. J. Psychiatry 2006, 188, 510-518.
    • (2006) Br. J. Psychiatry , vol.188 , pp. 510-518
    • Steen, R.G.1    Mull, C.2    McClure, R.3    Hamer, R.M.4    Lieberman, J.A.5
  • 116
    • 11344249233 scopus 로고    scopus 로고
    • The role of the hippocampus in the pathophysiology of major depression
    • Campbell, S.; Macqueen, G. The role of the hippocampus in the pathophysiology of major depression. J. Psychiatry Neurosci. 2004, 29, 417-426.
    • (2004) J. Psychiatry Neurosci , vol.29 , pp. 417-426
    • Campbell, S.1    Macqueen, G.2
  • 117
    • 34447120290 scopus 로고    scopus 로고
    • What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated
    • Czeh, B.; Lucassen, P. J. What causes the hippocampal volume decrease in depression? Are neurogenesis, glial changes and apoptosis implicated? Eur. Arch. Psychiatry Clin. Neurosci. 2007, 257, 250-260.
    • (2007) Eur. Arch. Psychiatry Clin. Neurosci , vol.257 , pp. 250-260
    • Czeh, B.1    Lucassen, P.J.2
  • 118
    • 0037839787 scopus 로고    scopus 로고
    • Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia
    • Hof, P. R.; Haroutunian, V.; Friedrich, V. L., Jr.; Byne, W.; Buitron, C.; Perl, D. P.; Davis, K. L. Loss and altered spatial distribution of oligodendrocytes in the superior frontal gyrus in schizophrenia. Biol. Psychiatry 2003, 53, 1075-1085.
    • (2003) Biol. Psychiatry , vol.53 , pp. 1075-1085
    • Hof, P.R.1    Haroutunian, V.2    Friedrich Jr., V.L.3    Byne, W.4    Buitron, C.5    Perl, D.P.6    Davis, K.L.7
  • 119
    • 1342300634 scopus 로고    scopus 로고
    • Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: A study from the Stanley Neuropathology Consortium
    • Uranova, N. A.; Vostrikov, V. M.; Orlovskaya, D. D.; Rachmanova, V. I. Oligodendroglial density in the prefrontal cortex in schizophrenia and mood disorders: a study from the Stanley Neuropathology Consortium. Schizophr. Res. 2004, 67, 269-275.
    • (2004) Schizophr. Res , vol.67 , pp. 269-275
    • Uranova, N.A.1    Vostrikov, V.M.2    Orlovskaya, D.D.3    Rachmanova, V.I.4
  • 120
    • 0025237883 scopus 로고
    • The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides
    • Longo, F. M.; Vu, T. K.; Mobley, W. C. The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides. Cell Regul. 1990, 1, 189-195.
    • (1990) Cell Regul , vol.1 , pp. 189-195
    • Longo, F.M.1    Vu, T.K.2    Mobley, W.C.3
  • 121
    • 0030972560 scopus 로고    scopus 로고
    • Peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism
    • Longo, F. M.; Manthorpe, M.; Xie, Y. M.; Varon, S. Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism. J. Neurosci. Res. 1997, 48, 1-17.
    • (1997) J. Neurosci. Res , vol.48 , pp. 1-17
    • Longo, F.M.1    Manthorpe, M.2    Xie, Y.M.3    Varon, S.4    Synthetic, N.G.F.5
  • 122
    • 4744347035 scopus 로고    scopus 로고
    • Effect of p75 neurotrophin receptor antagonist on disease progression in transgenic amyotrophic lateral sclerosis mice
    • Turner, B. J.; Murray, S. S.; Piccenna, L. G.; Lopes, E. C.; Kilpatrick, T. J.; Cheema, S. S. Effect of p75 neurotrophin receptor antagonist on disease progression in transgenic amyotrophic lateral sclerosis mice. J. Neurosci. Res. 2004, 78, 193-199.
    • (2004) J. Neurosci. Res , vol.78 , pp. 193-199
    • Turner, B.J.1    Murray, S.S.2    Piccenna, L.G.3    Lopes, E.C.4    Kilpatrick, T.J.5    Cheema, S.S.6
  • 124
    • 33748912842 scopus 로고    scopus 로고
    • Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain
    • Pehar, M.; Cassina, P.; Vargas, M. R.; Xie, Y.; Beckman, J. S.; Massa, S. M.; Longo, F. M.; Barbeito, L. Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. Eur. J. Neurosci. 2006, 24, 1575-1580.
    • (2006) Eur. J. Neurosci , vol.24 , pp. 1575-1580
    • Pehar, M.1    Cassina, P.2    Vargas, M.R.3    Xie, Y.4    Beckman, J.S.5    Massa, S.M.6    Longo, F.M.7    Barbeito, L.8


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