Selective activation of NF-κB by nerve growth factor through the neurotrophin receptor p75

Science

Volumn 272, Issue 5261, 1996, Pages 542-545

  Carter, Bruce D ^a,c   Kaltschmidt, Christian ^b   Kaltschmidt, Barbara ^b   Offenhäuser, Nina ^a,d   Böhm Matthaei, Renate ^a   Baeuerle, Patrick A ^b,e   Barde, Yves Alain ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

^d EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^e AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NERVE GROWTH FACTOR; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; MOUSE; NERVE GROWTH; NONHUMAN; PRIORITY JOURNAL; RAT; SCHWANN CELL; TRANSCRIPTION REGULATION;

EID: 0029869593     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.272.5261.542     Document Type: Article

References (38)

1. M. Barbacid, J. Neurobiol. 25, 1386 (1994).
2. A Rodríguez-Tébar, G. Dechant, Y.-A. Barde, Neuron 4, 487 (1990); A Rodríguez-Tébar, G. Dechant, R Gotz, Y -A Barde, EMBO J. 11, 917 (1992).
3. A Rodríguez-Tébar, G. Dechant, Y.-A. Barde, Neuron 4, 487 (1990); A Rodríguez-Tébar, G. Dechant, R Gotz, Y -A Barde, EMBO J. 11, 917 (1992).
4. D R. Kaplan and R. M Stephens, J. Neurobiol. 25, 1404 (1994).
5. B. L. Hempstead, D Martin-Zanca, D. R. Kaplan, L. F. Parada, M. V Chao, Nature 350, 678 (1991); D. S. Battleman, A. I. Geller, M. V Chao, J. Neurosci. 13, 941 (1993).
6. B. L. Hempstead, D Martin-Zanca, D. R. Kaplan, L. F. Parada, M. V Chao, Nature 350, 678 (1991); D. S. Battleman, A. I. Geller, M. V Chao, J. Neurosci. 13, 941 (1993).
7. J. M. Verdi et al., Neuron 12, 733 (1994); M. Benedetti, A. Levi, M. V. Chao, Proc. Natl. Acad. Sci. U.S.A. 90, 7859 (1993).
8. J. M. Verdi et al., Neuron 12, 733 (1994); M. Benedetti, A. Levi, M. V. Chao, Proc. Natl. Acad. Sci. U.S.A. 90, 7859 (1993).
9. S. Rabizadeh and D. E Bredesen, Dev. Neurosci. 16, 207 (1994).
10. E S Anton, G. Weskamp, L. F. Reichardt, W. D. Matthew, Proc. Natl Acad Sci U.S.A. 91, 2795 (1994).
11. R. T. Dobrowsky, M. H Werner, A. M Castellino, M. V Chao, Y. A. Hannun, Science 265, 1596 (1994).
12. L A Tartaglia, T. M Ayres, G H. W. Wong, D V. Goeddel, Cell 74, 845 (1993); L. A. Tartaglia and D. V. Goeddel, Immunol. Today 13, 151 (1992).
13. L A Tartaglia, T. M Ayres, G H. W. Wong, D V. Goeddel, Cell 74, 845 (1993); L. A. Tartaglia and D. V. Goeddel, Immunol. Today 13, 151 (1992).
14. P A. Baeuerle and T. Henkel, Annu. Rev Immunol. 12, 141 (1994).
15. M. Taniuchi, H. B. Clark, E M Johnson Jr , Proc. Natl. Acad Sci. U.S.A 83, 4094 (1986), R. Heumann et al , ibid. 84, 8735 (1987).
16. M. Taniuchi, H. B. Clark, E M Johnson Jr , Proc. Natl. Acad Sci. U.S.A 83, 4094 (1986), R. Heumann et al , ibid. 84, 8735 (1987).
17. R. T. Dobrowsky, G. M Jenkins, Y. A. Hannun, J. Biol Chem. 270, 22135 (1995).
18. NTR (5′-ATCGAATTCGTCGTGGGCCTTGTGG-3′) by 40 cycles (30 s at 95°C, 30 s at 55°C, and 45 s at 72°C). After separation on a 2% agarose gel, the bands were stained with ethidium bromide
19. NTR (5′-ATCGAATTCGTCGTGGGCCTTGTGG-3′) by 40 cycles (30 s at 95°C, 30 s at 55°C, and 45 s at 72°C). After separation on a 2% agarose gel, the bands were stained with ethidium bromide
20. N Offenhauser, R. Böhm-Matthaei, P. Tsoulfas, L. Parada, M. Meyer, Eur J. Neurosci. 7, 2005 (1995); H. Funakoshi et al., J Cell Biol. 123, 455 (1993), S. E. Sebert and E M Shooter, J. Neurosci. Res. 36, 357 (1993).
21. N Offenhauser, R. Böhm-Matthaei, P. Tsoulfas, L. Parada, M. Meyer, Eur J. Neurosci. 7, 2005 (1995); H. Funakoshi et al., J Cell Biol. 123, 455 (1993), S. E. Sebert and E M Shooter, J. Neurosci. Res. 36, 357 (1993).
22. N Offenhauser, R. Böhm-Matthaei, P. Tsoulfas, L. Parada, M. Meyer, Eur J. Neurosci. 7, 2005 (1995); H. Funakoshi et al., J Cell Biol. 123, 455 (1993), S. E. Sebert and E M Shooter, J. Neurosci. Res. 36, 357 (1993).
23. K-F. Lee et al., Cell 69, 737 (1992).
24. M J Radeke, T P. Misko, C. Hsu, L. A. Herzenberg, E. M. Shooter, Nature 325, 593 (1987).
25. B. D. Carter et al., data not shown.
26. J. N Wood, Neurosci. Lett. 192, 41 (1995)
27. B. Seilheimer and M Schachner, EMBO J. 6, 1611 (1987), K. Itoh, R. Brackenbury, R. A. Akeson, J. Neurosci. 15, 2504 (1995).
28. B. Seilheimer and M Schachner, EMBO J. 6, 1611 (1987), K. Itoh, R. Brackenbury, R. A. Akeson, J. Neurosci. 15, 2504 (1995).
29. G. R Lewin and L. M. Mendell, Trends Neurosci 16, 353 (1993); A Leon et al., Proc. Natl. Acad. Sci. U.S.A 91, 3739 (1994); U. Otten and R. A. Gadient, Int. J Dev. Neurosci. 13, 147 (1995).
30. G. R Lewin and L. M. Mendell, Trends Neurosci 16, 353 (1993); A Leon et al., Proc. Natl. Acad. Sci. U.S.A 91, 3739 (1994); U. Otten and R. A. Gadient, Int. J Dev. Neurosci. 13, 147 (1995).
31. G. R Lewin and L. M. Mendell, Trends Neurosci 16, 353 (1993); A Leon et al., Proc. Natl. Acad. Sci. U.S.A 91, 3739 (1994); U. Otten and R. A. Gadient, Int. J Dev. Neurosci. 13, 147 (1995).
32. C. J Woolf et al., Neuroscience 62, 327 (1994).
33. G. R. Lewin, Semin. Neurosci. 7, 227 (1995).
34. I. Matsuoka, M. Meyer, H. Thoenen, J. Neurosci. 11, 3165 (1991)
35. C. Kattschmidt, B. Kaltschmidt, P A. Baeuerle, Proc. Natl. Acad. Sci U S A 92, 9618 (1995)
36. C. Kattschmidt, B. Kaltschmidt, H. Neumann, H. Wekerle, P. A. Baeuerie, Mol. Cell. Biol. 14, 3981 (1994).
37. C. Kaltschmidt et al., Mech. Dev. 43, 135 (1993).
38. We thank H. Schätzl for help with the experiments, H Thoenen, G. R. Lewin, and G Dechant for comments on the manuscript; and Genentech, Inc , for the supply of CHO-derived human neurotrophins used in this study.