Survival of cholinergic forebrain neurons in developing p75(NGFR)- deficient mice

Science

Volumn 274, Issue 5293, 1996, Pages 1729-1732

  Van Der Zee, Catharina E E M ^a   Ross, Gregory M ^b   Riopelle, Richard J ^b   Hagg, Theo ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; CELL SURVIVAL; CHOLINERGIC TRANSMISSION; CONTROLLED STUDY; DIAGNOSIS; FOREBRAIN; GENE EXPRESSION REGULATION; MOUSE; NEUROMODULATION; NONHUMAN; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN DEFICIENCY;

ANIMALS; APOPTOSIS; CELL SURVIVAL; CHOLINE O-ACETYLTRANSFERASE; DNA FRAGMENTATION; INTERNEURONS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEOSTRIATUM; NEURONS; OLIGOPEPTIDES; PARASYMPATHETIC NERVOUS SYSTEM; PHOSPHORYLATION; PROSENCEPHALON; PROTO-ONCOGENE PROTEINS; PURKINJE CELLS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, NERVE GROWTH FACTOR; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR;

ANIMALIA;

EID: 0029829495     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.274.5293.1729     Document Type: Article

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36. NGFR and TrkA antibodies from L. F. Reichardt and the excellent technical support from J. Bunker, M. Netherton, and D. Sadi, We thank N. Tatton for guidance with the Apoptag method, J. Hebb for suggesting the peptide experiment, and E. M. Johnson, Jr. (Washington University, St. Louis, MO) and E. M. Shooter (Stanford University, CA) for their helpful input on the manuscript. Supported by Allelix Biopharmaceuticals, Mississauga, Ontario, Canada, and the Network of Centres of Excellence (Canada) (R.J.R. and T.H.) and a Scholarship from the Medical Research Council of Canada (T.H.).