-
1
-
-
71849111698
-
Signals and sequences that control CD28 localization to the central region of the immunological synapse
-
19017952
-
M Sanchez-Lockhart B Graf J Miller 2008 Signals and sequences that control CD28 localization to the central region of the immunological synapse J Immunol 181 7639 48 19017952
-
(2008)
J Immunol
, vol.181
, pp. 7639-48
-
-
Sanchez-Lockhart, M.1
Graf, B.2
Miller, J.3
-
2
-
-
58149280838
-
T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase Ctheta
-
18802089
-
SY Tseng JC Waite M Liu S Vardhana ML Dustin 2008 T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase Ctheta J Immunol 181 4852 4863 18802089
-
(2008)
J Immunol
, vol.181
, pp. 4852-4863
-
-
Tseng, S.Y.1
Waite, J.C.2
Liu, M.3
Vardhana, S.4
Dustin, M.L.5
-
4
-
-
0030176384
-
Upstream-downstream: CD28 cosignaling pathways and T cell function
-
8673699
-
C Rudd 1996 Upstream-downstream: CD28 cosignaling pathways and T cell function Immunity 4 527 534 8673699
-
(1996)
Immunity
, vol.4
, pp. 527-534
-
-
Rudd, C.1
-
5
-
-
0347505003
-
CD28-mediated co-stimulation; A quantitative support for TCR signaling
-
14647476
-
O Acuto F Michel 2003 CD28-mediated co-stimulation; a quantitative support for TCR signaling Nat Rev Immunol 3 939 951 14647476
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 939-951
-
-
Acuto, O.1
Michel, F.2
-
6
-
-
0142259712
-
Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling
-
12876557
-
C Rudd H Schneider 2003 Unifying concepts in CD28, ICOS and CTLA4 co-receptor signalling Nat Rev Immunol 3 544 556 12876557
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 544-556
-
-
Rudd, C.1
Schneider, H.2
-
7
-
-
0024506159
-
Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway
-
T Lindsten CH June JA Ledbetter G Stella CB Thompson 1989 Regulation of lymphokine messenger RNA stability by a surface-mediated T cell activation pathway Science 244 339 343
-
(1989)
Science
, vol.244
, pp. 339-343
-
-
Lindsten, T.1
June, C.H.2
Ledbetter, J.A.3
Stella, G.4
Thompson, C.B.5
-
8
-
-
0026061865
-
Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28
-
1846244
-
J Fraser B Irving G Crabtree A Weiss 1991 Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28 Science 251 313 316 1846244
-
(1991)
Science
, vol.251
, pp. 313-316
-
-
Fraser, J.1
Irving, B.2
Crabtree, G.3
Weiss, A.4
-
10
-
-
0036069699
-
The CD28 signalling pathway regulates glucose metabolism
-
12121659
-
K Frauwirth J Riley M Harris R Parry J Rathmell D Plas R Elstrom C June C Thompson 2002 The CD28 signalling pathway regulates glucose metabolism Immunity 16 769 777 12121659
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.1
Riley, J.2
Harris, M.3
Parry, R.4
Rathmell, J.5
Plas, D.6
Elstrom, R.7
June, C.8
Thompson, C.9
-
11
-
-
0025058266
-
Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody
-
2153162
-
M Jenkins C Chen G Jung D Mueller R Schwartz 1990 Inhibition of antigen-specific proliferation of type 1 murine T cell clones after stimulation with immobilized anti-CD3 monoclonal antibody J Immunol 144 16 22 2153162
-
(1990)
J Immunol
, vol.144
, pp. 16-22
-
-
Jenkins, M.1
Chen, C.2
Jung, G.3
Mueller, D.4
Schwartz, R.5
-
12
-
-
0026537347
-
CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
-
1313950
-
F Harding J McArthur J Gross D Raulet J Allison 1992 CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones Nature 356 607 609 1313950
-
(1992)
Nature
, vol.356
, pp. 607-609
-
-
Harding, F.1
McArthur, J.2
Gross, J.3
Raulet, D.4
Allison, J.5
-
15
-
-
13944260538
-
CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2
-
15640801
-
X Tai M Cowan L Feigenbaum A Singer 2005 CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2 Nat Immunol 6 152 162 15640801
-
(2005)
Nat Immunol
, vol.6
, pp. 152-162
-
-
Tai, X.1
Cowan, M.2
Feigenbaum, L.3
Singer, A.4
-
16
-
-
11144230063
-
The CD28 family: A T-cell rheostat for therapeutic control of T-cell activation
-
15353480
-
JL Riley CH June 2005 The CD28 family: a T-cell rheostat for therapeutic control of T-cell activation Blood 105 13 21 15353480
-
(2005)
Blood
, vol.105
, pp. 13-21
-
-
Riley, J.L.1
June, C.H.2
-
17
-
-
34447552443
-
TNF family ligands define niches for T cell memory
-
17597006
-
L Sabbagh LM Snell TH Watts 2007 TNF family ligands define niches for T cell memory Trends Immunol 28 333 339 17597006
-
(2007)
Trends Immunol
, vol.28
, pp. 333-339
-
-
Sabbagh, L.1
Snell, L.M.2
Watts, T.H.3
-
19
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
14749784
-
PJ Linton K Dorshkind 2004 Age-related changes in lymphocyte development and function Nat Immunol 5 133 139 14749784
-
(2004)
Nat Immunol
, vol.5
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
20
-
-
17144411571
-
T cell aging: Naive but not young
-
15781575
-
J Nikolich-Zugich 2005 T cell aging: naive but not young J Exp Med 201 837 840 15781575
-
(2005)
J Exp Med
, vol.201
, pp. 837-840
-
-
Nikolich-Zugich, J.1
-
23
-
-
20344375434
-
The effect of age on the cognate function of CD4+ T cells
-
15882356
-
L Haynes SM Eaton 2005 The effect of age on the cognate function of CD4+ T cells Immunol Rev 205 220 228 15882356
-
(2005)
Immunol Rev
, vol.205
, pp. 220-228
-
-
Haynes, L.1
Eaton, S.M.2
-
24
-
-
33744996006
-
Why aging T cells fail: Implications for vaccination
-
16782020
-
L Haynes SL Swain 2006 Why aging T cells fail: implications for vaccination Immunity 24 663 666 16782020
-
(2006)
Immunity
, vol.24
, pp. 663-666
-
-
Haynes, L.1
Swain, S.L.2
-
26
-
-
33845408098
-
High accumulation of T regulatory cells prevents the activation of immune responses in aged animals
-
17142731
-
S Sharma AL Dominguez J Lustgarten 2006 High accumulation of T regulatory cells prevents the activation of immune responses in aged animals J Immunol 177 8348 8355 17142731
-
(2006)
J Immunol
, vol.177
, pp. 8348-8355
-
-
Sharma, S.1
Dominguez, A.L.2
Lustgarten, J.3
-
27
-
-
23944501611
-
Signal transduction in the aging immune system
-
16061371
-
AA Sadighi Akha RA Miller 2005 Signal transduction in the aging immune system Curr Opin Immunol 17 486 491 16061371
-
(2005)
Curr Opin Immunol
, vol.17
, pp. 486-491
-
-
Sadighi Akha, A.A.1
Miller, R.A.2
-
28
-
-
0029918498
-
Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice
-
8642299
-
X Yang J Stedra J Cerny 1996 Relative contribution of T and B cells to hypermutation and selection of the antibody repertoire in germinal centers of aged mice J Exp Med 183 959 970 8642299
-
(1996)
J Exp Med
, vol.183
, pp. 959-970
-
-
Yang, X.1
Stedra, J.2
Cerny, J.3
-
29
-
-
0346422387
-
Antigen-specific CD4 T cell clonal expansion and differentiation in the aged lymphoid microenvironment. I. the primary T cell response is unaffected
-
14706237
-
JN Mittler WT Lee 2004 Antigen-specific CD4 T cell clonal expansion and differentiation in the aged lymphoid microenvironment. I. The primary T cell response is unaffected Mech Ageing Dev 125 47 57 14706237
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 47-57
-
-
Mittler, J.N.1
Lee, W.T.2
-
30
-
-
11844275234
-
Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses
-
15611289
-
SM Eaton EM Burns K Kusser TD Randall L Haynes 2004 Age-related defects in CD4 T cell cognate helper function lead to reductions in humoral responses J Exp Med 200 1613 1622 15611289
-
(2004)
J Exp Med
, vol.200
, pp. 1613-1622
-
-
Eaton, S.M.1
Burns, E.M.2
Kusser, K.3
Randall, T.D.4
Haynes, L.5
-
31
-
-
2142644403
-
Inflammatory Cytokines Overcome Age-Related Defects in CD4 T Cell Responses in Vivo
-
L Haynes SM Eaton EM Burns M Rincon SL Swain 2004 Inflammatory cytokines overcome age-related defects in CD4 T cell responses in vivo J Immunol 172 5194 5199 15100256 (Pubitemid 38542015)
-
(2004)
Journal of Immunology
, vol.172
, Issue.9
, pp. 5194-5199
-
-
Haynes, L.1
Eaton, S.M.2
Burns, E.M.3
Rincon, M.4
Swain, S.L.5
-
32
-
-
17144418549
-
Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen
-
15781577
-
L Haynes SM Eaton EM Burns TD Randall SL Swain 2005 Newly generated CD4 T cells in aged animals do not exhibit age-related defects in response to antigen J Exp Med 201 845 851 15781577
-
(2005)
J Exp Med
, vol.201
, pp. 845-851
-
-
Haynes, L.1
Eaton, S.M.2
Burns, E.M.3
Randall, T.D.4
Swain, S.L.5
-
33
-
-
0033523712
-
Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice
-
10510091
-
L Haynes PJ Linton SM Eaton SL Tonkonogy SL Swain 1999 Interleukin 2, but not other common gamma chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice J Exp Med 190 1013 1024 10510091
-
(1999)
J Exp Med
, vol.190
, pp. 1013-1024
-
-
Haynes, L.1
Linton, P.J.2
Eaton, S.M.3
Tonkonogy, S.L.4
Swain, S.L.5
-
34
-
-
0030293443
-
CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation
-
8892622
-
A Sperling J Auger B Ehst I Rulifson C Thompson J Bluestone 1996 CD28/B7 interactions deliver a unique signal to naive T cells that regulates cell survival but not early proliferation J Immunol 157 3909 3917 8892622
-
(1996)
J Immunol
, vol.157
, pp. 3909-3917
-
-
Sperling, A.1
Auger, J.2
Ehst, B.3
Rulifson, I.4
Thompson, C.5
Bluestone, J.6
-
35
-
-
20344379893
-
CD28 extinction in human T cells: Altered functions and the program of T-cell senescence
-
15882352
-
AN Vallejo 2005 CD28 extinction in human T cells: altered functions and the program of T-cell senescence Immunol Rev 205 158 169 15882352
-
(2005)
Immunol Rev
, vol.205
, pp. 158-169
-
-
Vallejo, A.N.1
-
36
-
-
34347405728
-
Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes
-
17570460
-
D Xie JE McElhaney 2007 Lower GrB+ CD62Lhigh CD8 TCM effector lymphocyte response to influenza virus in older adults is associated with increased CD28null CD8 T lymphocytes Mech Ageing Dev 128 392 400 17570460
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 392-400
-
-
Xie, D.1
McElhaney, J.E.2
-
37
-
-
0028182749
-
Binding of phosphatidyl-inositol-3-OH kinase to CD28 is required for T-cell signalling
-
DOI 10.1038/369327a0
-
F Pages M Rageuneau R Rottapel A Truneh J Nunes J Imbert D Olive 1994 Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling Nature 369 327 329 8183372 (Pubitemid 24159544)
-
(1994)
Nature
, vol.369
, Issue.6478
, pp. 327-329
-
-
Pages, F.1
Ragueneau, M.2
Rottapel, R.3
Truneh, A.4
Nunes, J.5
Imbert, J.6
Olive, D.7
-
38
-
-
0028802706
-
Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation
-
7584133
-
Y Cai D Cefai H Schneider M Raab N Nabavi C Rudd 1995 Selective CD28pYMNM mutations implicate phosphatidylinositol 3-kinase in CD86-CD28-mediated costimulation Immunity 3 417 426 7584133
-
(1995)
Immunity
, vol.3
, pp. 417-426
-
-
Cai, Y.1
Cefai, D.2
Schneider, H.3
Raab, M.4
Nabavi, N.5
Rudd, C.6
-
39
-
-
0031567886
-
Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK
-
8992971
-
P King A Sadra J Teng X Liu A Han A Selvakumar A August B Dupont 1997 Analysis of CD28 cytoplasmic tail tyrosine residues as regulators and substrates for the protein tyrosine kinases, EMT and LCK J Immunol 158 580 590 8992971
-
(1997)
J Immunol
, vol.158
, pp. 580-590
-
-
King, P.1
Sadra, A.2
Teng, J.3
Liu, X.4
Han, A.5
Selvakumar, A.6
August, A.7
Dupont, B.8
-
40
-
-
0031255110
-
The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28
-
9317120
-
L Marengere K Okkenhaug A Clavreul D Couez S Gibson G Mills T Mak R Rottapel 1997 The SH3 domain of Itk/Emt binds to proline-rich sequences in the cytoplasmic domain of the T cell costimulatory receptor CD28 J Immunol 159 3220 3229 9317120
-
(1997)
J Immunol
, vol.159
, pp. 3220-3229
-
-
Marengere, L.1
Okkenhaug, K.2
Clavreul, A.3
Couez, D.4
Gibson, S.5
Mills, G.6
Mak, T.7
Rottapel, R.8
-
41
-
-
18844473151
-
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes
-
10746729
-
Z Sun CW Arendt W Ellmeier EM Schaeffer MJ Sunshine L Gandhi J Annes D Petrzilka A Kupfer PL Schwartzberg DR Littman 2000 PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes Nature 404 402 407 10746729
-
(2000)
Nature
, vol.404
, pp. 402-407
-
-
Sun, Z.1
Arendt, C.W.2
Ellmeier, W.3
Schaeffer, E.M.4
Sunshine, M.J.5
Gandhi, L.6
Annes, J.7
Petrzilka, D.8
Kupfer, A.9
Schwartzberg, P.L.10
Littman, D.R.11
-
42
-
-
0036200194
-
Protein kinase B (Akt) regulation and function in T lymphocytes
-
11884227
-
D Cantrell 2002 Protein kinase B (Akt) regulation and function in T lymphocytes Semin Immunol 14 19 26 11884227
-
(2002)
Semin Immunol
, vol.14
, pp. 19-26
-
-
Cantrell, D.1
-
44
-
-
10844280747
-
CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway
-
15611240
-
LX Wu J La Rose L Chen C Neale T Mak K Okkenhaug R Wange R Rottapel 2005 CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway J Immunol 174 180 194 15611240
-
(2005)
J Immunol
, vol.174
, pp. 180-194
-
-
Wu, L.X.1
La Rose, J.2
Chen, L.3
Neale, C.4
Mak, T.5
Okkenhaug, K.6
Wange, R.7
Rottapel, R.8
-
46
-
-
27744519400
-
Fuel feeds function: Energy metabolism and the T-cell response
-
16239903
-
CJ Fox PS Hammerman CB Thompson 2005 Fuel feeds function: energy metabolism and the T-cell response Nat Rev Immunol 5 844 852 16239903
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 844-852
-
-
Fox, C.J.1
Hammerman, P.S.2
Thompson, C.B.3
-
47
-
-
0035221568
-
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-γ but not Th2 cytokines
-
11135576
-
L Kane P Andres K Howland A Abbas A Weiss 2001 Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-γ but not Th2 cytokines Nat Immunol 2 37 44 11135576
-
(2001)
Nat Immunol
, vol.2
, pp. 37-44
-
-
Kane, L.1
Andres, P.2
Howland, K.3
Abbas, A.4
Weiss, A.5
-
48
-
-
0028972549
-
CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase
-
7594470
-
K Truitt J Shi S Gibson L Segal G Mills J Imboden 1995 CD28 delivers costimulatory signals independently of its association with phosphatidylinositol 3-kinase J Immunol 155 4702 4710 7594470
-
(1995)
J Immunol
, vol.155
, pp. 4702-4710
-
-
Truitt, K.1
Shi, J.2
Gibson, S.3
Segal, L.4
Mills, G.5
Imboden, J.6
-
49
-
-
0028972712
-
CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation
-
8524248
-
M Crooks D Littman R Carter D Fearon A Weiss P Stein 1995 CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation Mol Cell Biol 15 6820 6828 8524248
-
(1995)
Mol Cell Biol
, vol.15
, pp. 6820-6828
-
-
Crooks, M.1
Littman, D.2
Carter, R.3
Fearon, D.4
Weiss, A.5
Stein, P.6
-
50
-
-
0033811659
-
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
-
10958690
-
X Shan M Czar S Bunnel P Liu Y Liu P Schwartzberg R Wange 2000 Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation Mol Cell Biol 20 6945 6957 10958690
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6945-6957
-
-
Shan, X.1
Czar, M.2
Bunnel, S.3
Liu, P.4
Liu, Y.5
Schwartzberg, P.6
Wange, R.7
-
51
-
-
0037111475
-
Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors
-
12421919
-
R Freeburn K Wright S Burgess E Astoul D Cantrell S Ward 2002 Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors J Immunol 169 5441 5450 12421919
-
(2002)
J Immunol
, vol.169
, pp. 5441-5450
-
-
Freeburn, R.1
Wright, K.2
Burgess, S.3
Astoul, E.4
Cantrell, D.5
Ward, S.6
-
52
-
-
0035319244
-
A point mutation in CD28 distinguishes proliferative signals from survival signals
-
11276203
-
K Okkenhaug L Wu K Garza J La Rose W Khoo B Odermatt T Mak P Ohashi R Rottapel 2001 A point mutation in CD28 distinguishes proliferative signals from survival signals Nat Immunol 2 325 332 11276203
-
(2001)
Nat Immunol
, vol.2
, pp. 325-332
-
-
Okkenhaug, K.1
Wu, L.2
Garza, K.3
La Rose, J.4
Khoo, W.5
Odermatt, B.6
Mak, T.7
Ohashi, P.8
Rottapel, R.9
-
53
-
-
0035869402
-
Critical requirement for the membrane-proximal tyrosine residue for CD28-mediated costimulation in vivo
-
11238622
-
Y Harada M Tokushima Y Matsumoto S Ogawa M Otsuka K Hayashi B Weiss C June R Abe 2001 Critical requirement for the membrane-proximal tyrosine residue for CD28-mediated costimulation in vivo J Immunol 166 3797 3803 11238622
-
(2001)
J Immunol
, vol.166
, pp. 3797-3803
-
-
Harada, Y.1
Tokushima, M.2
Matsumoto, Y.3
Ogawa, S.4
Otsuka, M.5
Hayashi, K.6
Weiss, B.7
June, C.8
Abe, R.9
-
54
-
-
0035340150
-
Distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL
-
11313368
-
J Burr N Savage G Messah S Kimzey A Shaw R Arch J Green 2001 Distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL J Immunol 166 5331 5335 11313368
-
(2001)
J Immunol
, vol.166
, pp. 5331-5335
-
-
Burr, J.1
Savage, N.2
Messah, G.3
Kimzey, S.4
Shaw, A.5
Arch, R.6
Green, J.7
-
55
-
-
11144358624
-
Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation
-
15004555
-
P Andres K Howland A Nirula L Kane L Barron D Dresnek A Sadra J Imboden A Weiss A Abbas 2004 Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation Nat Immunol 5 435 442 15004555
-
(2004)
Nat Immunol
, vol.5
, pp. 435-442
-
-
Andres, P.1
Howland, K.2
Nirula, A.3
Kane, L.4
Barron, L.5
Dresnek, D.6
Sadra, A.7
Imboden, J.8
Weiss, A.9
Abbas, A.10
-
56
-
-
10344237020
-
CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways
-
15585831
-
M Sanchez-Lockhart E Marin B Graf R Abe Y Harada CE Sedwick J Miller 2004 CD28-mediated transcriptional and posttranscriptional regulation of IL-2 expression are controlled through different signaling pathways J Immunol 173 7120 7124 15585831
-
(2004)
J Immunol
, vol.173
, pp. 7120-7124
-
-
Sanchez-Lockhart, M.1
Marin, E.2
Graf, B.3
Abe, R.4
Harada, Y.5
Sedwick, C.E.6
Miller, J.7
-
57
-
-
33947599936
-
Physiologic and aberrant regulation of memory T-cell trafficking by the costimulatory molecule CD28
-
17119120
-
V Mirenda SJ Jarmin R David J Dyson D Scott Y Gu RI Lechler K Okkenhaug FM Marelli-Berg 2007 Physiologic and aberrant regulation of memory T-cell trafficking by the costimulatory molecule CD28 Blood 109 2968 2977 17119120
-
(2007)
Blood
, vol.109
, pp. 2968-2977
-
-
Mirenda, V.1
Jarmin, S.J.2
David, R.3
Dyson, J.4
Scott, D.5
Gu, Y.6
Lechler, R.I.7
Okkenhaug, K.8
Marelli-Berg, F.M.9
-
59
-
-
38949150779
-
CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer
-
18006698
-
F Garcon DT Patton JL Emery E Hirsch R Rottapel T Sasaki K Okkenhaug 2008 CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer Blood 111 1464 1471 18006698
-
(2008)
Blood
, vol.111
, pp. 1464-1471
-
-
Garcon, F.1
Patton, D.T.2
Emery, J.L.3
Hirsch, E.4
Rottapel, R.5
Sasaki, T.6
Okkenhaug, K.7
-
60
-
-
0031962106
-
Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling
-
9417079
-
HH Kim M Tharayil CE Rudd 1998 Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling J Biol Chem 273 296 301 9417079
-
(1998)
J Biol Chem
, vol.273
, pp. 296-301
-
-
Kim, H.H.1
Tharayil, M.2
Rudd, C.E.3
-
61
-
-
0032516873
-
Grb2 forms an inducible protein complex with CD28 through a src homology 3 domain-proline interaction
-
9694876
-
K Okkenhaug R Rottapel 1998 Grb2 forms an inducible protein complex with CD28 through a src homology 3 domain-proline interaction J Biol Chem 273 21194 21202 9694876
-
(1998)
J Biol Chem
, vol.273
, pp. 21194-21202
-
-
Okkenhaug, K.1
Rottapel, R.2
-
62
-
-
0034041979
-
GRID: A novel Grb-2 related adapter protein that interacts with the activated T cell costimulatory receptor CD28
-
10820259
-
J Ellis C Ashman M Burden K Kilpatrick M Morse P Hamblin 2000 GRID: a novel Grb-2 related adapter protein that interacts with the activated T cell costimulatory receptor CD28 J Immunol 164 5805 5814 10820259
-
(2000)
J Immunol
, vol.164
, pp. 5805-5814
-
-
Ellis, J.1
Ashman, C.2
Burden, M.3
Kilpatrick, K.4
Morse, M.5
Hamblin, P.6
-
63
-
-
33745827029
-
Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation
-
16818765
-
R Watanabe Y Harada K Takeda J Takahashi K Ohnuki S Ogawa D Ohgai N Kaibara O Koiwai K Tanabe H Toma K Sugamura R Abe 2006 Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation J Immunol 177 1085 1091 16818765
-
(2006)
J Immunol
, vol.177
, pp. 1085-1091
-
-
Watanabe, R.1
Harada, Y.2
Takeda, K.3
Takahashi, J.4
Ohnuki, K.5
Ogawa, S.6
Ohgai, D.7
Kaibara, N.8
Koiwai, O.9
Tanabe, K.10
Toma, H.11
Sugamura, K.12
Abe, R.13
-
64
-
-
0028169441
-
The role of p21ras in CD28 signal transduction: Triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras
-
7520466
-
J Nunes Y Collette A Truneh D Olive D Cantrell 1994 The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras J Exp Med 180 1067 1076 7520466
-
(1994)
J Exp Med
, vol.180
, pp. 1067-1076
-
-
Nunes, J.1
Collette, Y.2
Truneh, A.3
Olive, D.4
Cantrell, D.5
-
65
-
-
0035876136
-
Novel recognition mode between Vav and Grb2 SH3 domains
-
11406576
-
M Nishida K Nagata Y Hachimori M Horiuchi K Ogura V Mandiyan J Schlessinger F Inagaki 2001 Novel recognition mode between Vav and Grb2 SH3 domains EMBO J 20 2995 3007 11406576
-
(2001)
EMBO J
, vol.20
, pp. 2995-3007
-
-
Nishida, M.1
Nagata, K.2
Hachimori, Y.3
Horiuchi, M.4
Ogura, K.5
Mandiyan, V.6
Schlessinger, J.7
Inagaki, F.8
-
66
-
-
0034637536
-
Synergistic activation of NF-κB by functional cooperation between vav and PKCθ in T lymphocytes
-
10862755
-
O Dienz SP Hehner W Droge ML Schmitz 2000 Synergistic activation of NF-κB by functional cooperation between vav and PKCθ in T lymphocytes J Biol Chem 275 24547 24551 10862755
-
(2000)
J Biol Chem
, vol.275
, pp. 24547-24551
-
-
Dienz, O.1
Hehner, S.P.2
Droge, W.3
Schmitz, M.L.4
-
67
-
-
0034674627
-
Tyrosine-phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription
-
10849438
-
SP Hehner TG Hofmann O Dienz W Droge ML Schmitz 2000 Tyrosine- phosphorylated Vav1 as a point of integration for T-cell receptor- and CD28-mediated activation of JNK, p38, and interleukin-2 transcription J Biol Chem 275 18160 18171 10849438
-
(2000)
J Biol Chem
, vol.275
, pp. 18160-18171
-
-
Hehner, S.P.1
Hofmann, T.G.2
Dienz, O.3
Droge, W.4
Schmitz, M.L.5
-
68
-
-
0034292369
-
CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation
-
11034388
-
F Michel G Mangino G Attal-Bonnefoy L Tuosto A Alcover A Roumier D Olive O Acuto 2000 CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation J Immunol 165 3820 3829 11034388
-
(2000)
J Immunol
, vol.165
, pp. 3820-3829
-
-
Michel, F.1
Mangino, G.2
Attal-Bonnefoy, G.3
Tuosto, L.4
Alcover, A.5
Roumier, A.6
Olive, D.7
Acuto, O.8
-
69
-
-
0034288906
-
A novel functional interaction between Vav and PKCθ is required for TCR-induced T cell activation
-
10714681
-
M Villalba N Coudronniere M Deckert E Teixeiro P Mas A Altman 2000 A novel functional interaction between Vav and PKCθ is required for TCR-induced T cell activation Immunity 12 151 160 10714681
-
(2000)
Immunity
, vol.12
, pp. 151-160
-
-
Villalba, M.1
Coudronniere, N.2
Deckert, M.3
Teixeiro, E.4
Mas, P.5
Altman, A.6
-
70
-
-
0028291525
-
JNK is involved in signal integration during costimulation of T lymphocytes
-
8205621
-
B Su E Jacinto M Hibi T Kallunki M Karin Y Ben-Neriah 1994 JNK is involved in signal integration during costimulation of T lymphocytes Cell 77 727 736 8205621
-
(1994)
Cell
, vol.77
, pp. 727-736
-
-
Su, B.1
Jacinto, E.2
Hibi, M.3
Kallunki, T.4
Karin, M.5
Ben-Neriah, Y.6
-
71
-
-
0032570874
-
Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes
-
9478939
-
K Reedquist J Bos 1998 Costimulation through CD28 suppresses T cell receptor-dependent activation of the Ras-like small GTPase Rap1 in human T lymphocytes J Biol Chem 273 4944 4949 9478939
-
(1998)
J Biol Chem
, vol.273
, pp. 4944-4949
-
-
Reedquist, K.1
Bos, J.2
-
72
-
-
0033756553
-
CD28 and the tyrosine kinase Lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1
-
11046138
-
K Carey T Dillon J Schmitt A Baird A Holdorf D Straus A Shaw P Stork 2000 CD28 and the tyrosine kinase Lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1 Mol Cell Biol 20 8409 8419 11046138
-
(2000)
Mol Cell Biol
, vol.20
, pp. 8409-8419
-
-
Carey, K.1
Dillon, T.2
Schmitt, J.3
Baird, A.4
Holdorf, A.5
Straus, D.6
Shaw, A.7
Stork, P.8
-
73
-
-
0028146530
-
CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the TEC family kinase ITK/EMT in the human Jurkat leukemic T-cell line
-
7524075
-
A August S Gibson T Kawakami GB Mills B Dupont 1994 CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the TEC family kinase ITK/EMT in the human Jurkat leukemic T-cell line Proc Natl Acad Sci USA 91 9347 9351 7524075
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9347-9351
-
-
August, A.1
Gibson, S.2
Kawakami, T.3
Mills, G.B.4
Dupont, B.5
-
75
-
-
33746210261
-
Filamin A is required for T cell activation mediated by protein kinase C-theta
-
16849481
-
K Hayashi A Altman 2006 Filamin A is required for T cell activation mediated by protein kinase C-theta J Immunol 177 1721 1728 16849481
-
(2006)
J Immunol
, vol.177
, pp. 1721-1728
-
-
Hayashi, K.1
Altman, A.2
-
76
-
-
7944237936
-
The many faces of filamin: A versatile molecular scaffold for cell motility and signalling
-
15516996
-
Y Feng CA Walsh 2004 The many faces of filamin: a versatile molecular scaffold for cell motility and signalling Nat Cell Biol 6 1034 1038 15516996
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1034-1038
-
-
Feng, Y.1
Walsh, C.A.2
-
78
-
-
15444373759
-
Multiple modes of interaction between Lck and CD28
-
15778335
-
E Hofinger H Sticht 2005 Multiple modes of interaction between Lck and CD28 J Immunol 174 3839 3840 15778335
-
(2005)
J Immunol
, vol.174
, pp. 3839-3840
-
-
Hofinger, E.1
Sticht, H.2
-
79
-
-
0033517125
-
Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation
-
10430626
-
AD Holdorf JM Green SD Levin MF Denny DB Straus V Link PS Changelian PM Allen AS Shaw 1999 Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation J Exp Med 190 375 384 10430626
-
(1999)
J Exp Med
, vol.190
, pp. 375-384
-
-
Holdorf, A.D.1
Green, J.M.2
Levin, S.D.3
Denny, M.F.4
Straus, D.B.5
Link, V.6
Changelian, P.S.7
Allen, P.M.8
Shaw, A.S.9
-
80
-
-
0028981212
-
P56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: Implications for T-cell costimulation
-
7568038
-
M Raab YC Cai SC Bunnell SD Heyeck LJ Berg CE Rudd 1995 p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation Proc Natl Acad Sci USA 92 8891 8895 7568038
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8891-8895
-
-
Raab, M.1
Cai, Y.C.2
Bunnell, S.C.3
Heyeck, S.D.4
Berg, L.J.5
Rudd, C.E.6
-
81
-
-
53149114893
-
CD28 controls differentiation of regulatory T cells from naive CD4 T cells
-
18684917
-
F Guo C Iclozan WK Suh C Anasetti XZ Yu 2008 CD28 controls differentiation of regulatory T cells from naive CD4 T cells J Immunol 181 2285 2291 18684917
-
(2008)
J Immunol
, vol.181
, pp. 2285-2291
-
-
Guo, F.1
Iclozan, C.2
Suh, W.K.3
Anasetti, C.4
Yu, X.Z.5
-
82
-
-
34548718561
-
Induction of autoimmune disease in CTLA-4-/- mice depends on a specific CD28 motif that is required for in vivo costimulation
-
17702861
-
X Tai F Van Laethem AH Sharpe A Singer 2007 Induction of autoimmune disease in CTLA-4-/- mice depends on a specific CD28 motif that is required for in vivo costimulation Proc Natl Acad Sci USA 104 13756 13761 17702861
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13756-13761
-
-
Tai, X.1
Van Laethem, F.2
Sharpe, A.H.3
Singer, A.4
-
83
-
-
33748468629
-
A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant
-
16908623
-
LD Friend DD Shah C Deppong J Lin TL Bricker TI Juehne CM Rose JM Green 2006 A dose-dependent requirement for the proline motif of CD28 in cellular and humoral immunity revealed by a targeted knockin mutant J Exp Med 203 2121 2133 16908623
-
(2006)
J Exp Med
, vol.203
, pp. 2121-2133
-
-
Friend, L.D.1
Shah, D.D.2
Deppong, C.3
Lin, J.4
Bricker, T.L.5
Juehne, T.I.6
Rose, C.M.7
Green, J.M.8
-
85
-
-
0037015038
-
Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation
-
12195013
-
M Diehn A Alizadeh O Rando C Liu K Stankunas D Botstein G Crabtree P Brown 2002 Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation Proc Natl Acad Sci USA 99 11796 11801 12195013
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11796-11801
-
-
Diehn, M.1
Alizadeh, A.2
Rando, O.3
Liu, C.4
Stankunas, K.5
Botstein, D.6
Crabtree, G.7
Brown, P.8
-
86
-
-
0037015055
-
Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors
-
12195015
-
J Riley M Mao S Kobayashi M Biery J Burchard G Cavet B Gregson C June P Linsley 2002 Modulation of TCR-induced transcriptional profiles by ligation of CD28, ICOS, and CTLA-4 receptors Proc Natl Acad Sci USA 99 11790 11795 12195015
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11790-11795
-
-
Riley, J.1
Mao, M.2
Kobayashi, S.3
Biery, M.4
Burchard, J.5
Cavet, G.6
Gregson, B.7
June, C.8
Linsley, P.9
-
87
-
-
0035059418
-
The immunological synapse
-
SK Bromley WR Burack KG Johnson K Somersalo TN Sims C Sumen MM Davis AS Shaw PM Allen ML Dustin 2001 The immunological synapse Ann Rev Immunol 19 375 396
-
(2001)
Ann Rev Immunol
, vol.19
, pp. 375-396
-
-
Bromley, S.K.1
Burack, W.R.2
Johnson, K.G.3
Somersalo, K.4
Sims, T.N.5
Sumen, C.6
Davis, M.M.7
Shaw, A.S.8
Allen, P.M.9
Dustin, M.L.10
-
88
-
-
0034644505
-
Signaling takes shape in the immune system
-
11057901
-
ML Dustin AC Chan 2000 Signaling takes shape in the immune system Cell 103 283 294 11057901
-
(2000)
Cell
, vol.103
, pp. 283-294
-
-
Dustin, M.L.1
Chan, A.C.2
-
89
-
-
0036604984
-
Formation and function of the immunological synapse
-
11973125
-
P van der Merwe 2002 Formation and function of the immunological synapse Curr Opin Immunol 14 293 298 11973125
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 293-298
-
-
Van Der Merwe, P.1
-
90
-
-
0346244099
-
T-cell-antigen recognition and the immunological synapse
-
14647479
-
J Huppa M Davis 2003 T-cell-antigen recognition and the immunological synapse Nat Rev Immunol 3 973 983 14647479
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 973-983
-
-
Huppa, J.1
Davis, M.2
-
91
-
-
0032480279
-
Three-dimensional segregation of supramolecular activation clusters in T cells
-
9738502
-
C Monks B Freiberg H Kupfer N Sciaky A Kupfer 1998 Three-dimensional segregation of supramolecular activation clusters in T cells Nature 395 82 86 9738502
-
(1998)
Nature
, vol.395
, pp. 82-86
-
-
Monks, C.1
Freiberg, B.2
Kupfer, H.3
Sciaky, N.4
Kupfer, A.5
-
92
-
-
0026559329
-
Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells
-
1349172
-
Y Liu C Janeway 1992 Cells that present both specific ligand and costimulatory activity are the most efficient inducers of clonal expansion of normal CD4 T cells Proc Natl Acad Sci USA 89 3845 3849 1349172
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3845-3849
-
-
Liu, Y.1
Janeway, C.2
-
93
-
-
0031012266
-
Selective modulation of protein kinase C-θ during T cell activation
-
8985252
-
C Monks H Kupfer I Tamir A Barlow A Kupfer 1997 Selective modulation of protein kinase C-θ during T cell activation Nature 385 83 86 8985252
-
(1997)
Nature
, vol.385
, pp. 83-86
-
-
Monks, C.1
Kupfer, H.2
Tamir, I.3
Barlow, A.4
Kupfer, A.5
-
94
-
-
0033538574
-
The immunological synapse: A molecular machine controlling T cell activation
-
DOI 10.1126/science.285.5425.221
-
A Grakoui S Bromley C Sumen M Davis A Shaw P Allen M Dustin 1999 The immunological synapse: a molecular machine controlling T cell activation Science 285 221 227 10398592 (Pubitemid 29329988)
-
(1999)
Science
, vol.285
, Issue.5425
, pp. 221-227
-
-
Grakoui, A.1
Bromley, S.K.2
Sumen, C.3
Davis, M.M.4
Shaw, A.S.5
Allen, P.M.6
Dustin, M.L.7
-
95
-
-
0034714184
-
Differential clustering of CD4 and CD3ζ during T cell recognition
-
10958781
-
MF Krummel MD Sjaastad C Wulfing MM Davis 2000 Differential clustering of CD4 and CD3ζ during T cell recognition Science 289 1349 1352 10958781
-
(2000)
Science
, vol.289
, pp. 1349-1352
-
-
Krummel, M.F.1
Sjaastad, M.D.2
Wulfing, C.3
Davis, M.M.4
-
96
-
-
0034730188
-
A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation
-
10963676
-
K Johnson S Bromley M Dustin M Thomas 2000 A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation Proc Natl Acad Sci USA 97 10138 10143 10963676
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 10138-10143
-
-
Johnson, K.1
Bromley, S.2
Dustin, M.3
Thomas, M.4
-
97
-
-
0035202768
-
The immunological synapse and CD28-CD80 interactions
-
11713465
-
S Bromley A Iaboni S Davis A Whitty J Green A Shaw A Weiss M Dustin 2001 The immunological synapse and CD28-CD80 interactions Nat Immunol 2 1159 1166 11713465
-
(2001)
Nat Immunol
, vol.2
, pp. 1159-1166
-
-
Bromley, S.1
Iaboni, A.2
Davis, S.3
Whitty, A.4
Green, J.5
Shaw, A.6
Weiss, A.7
Dustin, M.8
-
98
-
-
0037154747
-
T cell receptor signaling precedes immunological synapse formation
-
11859198
-
K Lee A Holdorf M Dustin A Chan P Allen A Shaw 2002 T cell receptor signaling precedes immunological synapse formation Science 295 1539 1542 11859198
-
(2002)
Science
, vol.295
, pp. 1539-1542
-
-
Lee, K.1
Holdorf, A.2
Dustin, M.3
Chan, A.4
Allen, P.5
Shaw, A.6
-
101
-
-
0032534304
-
TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site
-
9862667
-
AI Sperling JR Sedy N Manjunath A Kupfer B Ardman JK Burkhardt 1998 TCR signaling induces selective exclusion of CD43 from the T cell-antigen-presenting cell contact site J Immunol 161 6459 6462 9862667
-
(1998)
J Immunol
, vol.161
, pp. 6459-6462
-
-
Sperling, A.I.1
Sedy, J.R.2
Manjunath, N.3
Kupfer, A.4
Ardman, B.5
Burkhardt, J.K.6
-
103
-
-
27544441784
-
Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling
-
16216891
-
G Campi R Varma ML Dustin 2005 Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling J Exp Med 202 1031 1036 16216891
-
(2005)
J Exp Med
, vol.202
, pp. 1031-1036
-
-
Campi, G.1
Varma, R.2
Dustin, M.L.3
-
104
-
-
30044441433
-
Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76
-
16273097
-
T Yokosuka K Sakata-Sogawa W Kobayashi M Hiroshima A Hashimoto-Tane M Tokunaga ML Dustin T Saito 2005 Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76 Nat Immunol 6 1253 1262 16273097
-
(2005)
Nat Immunol
, vol.6
, pp. 1253-1262
-
-
Yokosuka, T.1
Sakata-Sogawa, K.2
Kobayashi, W.3
Hiroshima, M.4
Hashimoto-Tane, A.5
Tokunaga, M.6
Dustin, M.L.7
Saito, T.8
-
105
-
-
33746011209
-
T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster
-
16860761
-
R Varma G Campi T Yokosuka T Saito ML Dustin 2006 T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster Immunity 25 117 127 16860761
-
(2006)
Immunity
, vol.25
, pp. 117-127
-
-
Varma, R.1
Campi, G.2
Yokosuka, T.3
Saito, T.4
Dustin, M.L.5
-
106
-
-
54949103906
-
Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation
-
18848472
-
T Yokosuka W Kobayashi K Sakata-Sogawa M Takamatsu A Hashimoto-Tane ML Dustin M Tokunaga T Saito 2008 Spatiotemporal regulation of T cell costimulation by TCR-CD28 microclusters and protein kinase C theta translocation Immunity 29 589 601 18848472
-
(2008)
Immunity
, vol.29
, pp. 589-601
-
-
Yokosuka, T.1
Kobayashi, W.2
Sakata-Sogawa, K.3
Takamatsu, M.4
Hashimoto-Tane, A.5
Dustin, M.L.6
Tokunaga, M.7
Saito, T.8
-
107
-
-
34548650329
-
LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse
-
17641028
-
B Graf T Bushnell J Miller 2007 LFA-1-mediated T cell costimulation through increased localization of TCR/class II complexes to the central supramolecular activation cluster and exclusion of CD45 from the immunological synapse J Immunol 179 1616 1624 17641028
-
(2007)
J Immunol
, vol.179
, pp. 1616-1624
-
-
Graf, B.1
Bushnell, T.2
Miller, J.3
-
108
-
-
0242497659
-
The immunological synapse balances T cell receptor signaling and degradation
-
14512504
-
K-H Lee A Dinner C Tu G Campi S Raychaudhuri R Varma T Sims W Burack H Wu J Wang O Kanagawa M Markiewicz P Allen M Dustin A Chakraborty A Shaw 2003 The immunological synapse balances T cell receptor signaling and degradation Science 302 1218 1222 14512504
-
(2003)
Science
, vol.302
, pp. 1218-1222
-
-
Lee, K.-H.1
Dinner, A.2
Tu, C.3
Campi, G.4
Raychaudhuri, S.5
Varma, R.6
Sims, T.7
Burack, W.8
Wu, H.9
Wang, J.10
Kanagawa, O.11
Markiewicz, M.12
Allen, P.13
Dustin, M.14
Chakraborty, A.15
Shaw, A.16
-
109
-
-
51349131307
-
The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality
-
18760640
-
S Cemerski J Das E Giurisato MA Markiewicz PM Allen AK Chakraborty AS Shaw 2008 The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality Immunity 29 414 422 18760640
-
(2008)
Immunity
, vol.29
, pp. 414-422
-
-
Cemerski, S.1
Das, J.2
Giurisato, E.3
Markiewicz, M.A.4
Allen, P.M.5
Chakraborty, A.K.6
Shaw, A.S.7
-
110
-
-
33947189706
-
The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse
-
17346997
-
S Cemerski J Das J Locasale P Arnold E Giurisato MA Markiewicz D Fremont PM Allen AK Chakraborty AS Shaw 2007 The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse Immunity 26 345 355 17346997
-
(2007)
Immunity
, vol.26
, pp. 345-355
-
-
Cemerski, S.1
Das, J.2
Locasale, J.3
Arnold, P.4
Giurisato, E.5
Markiewicz, M.A.6
Fremont, D.7
Allen, P.M.8
Chakraborty, A.K.9
Shaw, A.S.10
-
111
-
-
0033625869
-
Protein kinase Cθ: A new essential superstar on the T-cell stage
-
11094261
-
A Altman N Isakov G Baier 2000 Protein kinase Cθ: a new essential superstar on the T-cell stage Immunol Today 21 567 573 11094261
-
(2000)
Immunol Today
, vol.21
, pp. 567-573
-
-
Altman, A.1
Isakov, N.2
Baier, G.3
-
112
-
-
15944410614
-
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation
-
15802604
-
KY Lee F D'Acquisto MS Hayden JH Shim S Ghosh 2005 PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation Science 308 114 118 15802604
-
(2005)
Science
, vol.308
, pp. 114-118
-
-
Lee, K.Y.1
D'Acquisto, F.2
Hayden, M.S.3
Shim, J.H.4
Ghosh, S.5
-
114
-
-
33645787258
-
Engagement of CD28 outside of the immunological synapse results in upregulation of IL-2 mRNA stability, but not IL-2 transcription
-
16585571
-
M Sanchez-Lockhart J Miller 2006 Engagement of CD28 outside of the immunological synapse results in upregulation of IL-2 mRNA stability, but not IL-2 transcription J Immunol 176 4778 4784 16585571
-
(2006)
J Immunol
, vol.176
, pp. 4778-4784
-
-
Sanchez-Lockhart, M.1
Miller, J.2
-
115
-
-
40949102111
-
Post-transcriptional control of cytokine production
-
18349815
-
P Anderson 2008 Post-transcriptional control of cytokine production Nat Immunol 9 353 359 18349815
-
(2008)
Nat Immunol
, vol.9
, pp. 353-359
-
-
Anderson, P.1
-
117
-
-
0038652204
-
The control of mRNA stability in response to extracellular signals
-
12521293
-
J Shim M Karin 2002 The control of mRNA stability in response to extracellular signals Mol Cells 14 323 331 12521293
-
(2002)
Mol Cells
, vol.14
, pp. 323-331
-
-
Shim, J.1
Karin, M.2
-
118
-
-
7944225681
-
Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation
-
15533717
-
A Raghavan M Dhalla T Bakheet RL Ogilvie IA Vlasova KS Khabar BR Williams PR Bohjanen 2004 Patterns of coordinate down-regulation of ARE-containing transcripts following immune cell activation Genomics 84 1002 1013 15533717
-
(2004)
Genomics
, vol.84
, pp. 1002-1013
-
-
Raghavan, A.1
Dhalla, M.2
Bakheet, T.3
Ogilvie, R.L.4
Vlasova, I.A.5
Khabar, K.S.6
Williams, B.R.7
Bohjanen, P.R.8
-
119
-
-
0037115826
-
Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes
-
12490721
-
A Raghavan RL Ogilvie C Reilly ML Abelson S Raghavan J Vasdewani M Krathwohl PR Bohjanen 2002 Genome-wide analysis of mRNA decay in resting and activated primary human T lymphocytes Nucl Acids Res 30 5529 5538 12490721
-
(2002)
Nucl Acids Res
, vol.30
, pp. 5529-5538
-
-
Raghavan, A.1
Ogilvie, R.L.2
Reilly, C.3
Abelson, M.L.4
Raghavan, S.5
Vasdewani, J.6
Krathwohl, M.7
Bohjanen, P.R.8
-
120
-
-
42449120163
-
Decoding ARE-mediated decay: Is microRNA part of the equation?
-
C von Roretz IE Gallouzi 2008 Decoding ARE-mediated decay: is microRNA part of the equation? J Cell Biol 181 189 194
-
(2008)
J Cell Biol
, vol.181
, pp. 189-194
-
-
Von Roretz, C.1
Gallouzi, I.E.2
-
121
-
-
45249099847
-
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin
-
18256032
-
G Stoecklin SA Tenenbaum T Mayo SV Chittur AD George TE Baroni PJ Blackshear P Anderson 2008 Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin J Biol Chem 283 11689 11699 18256032
-
(2008)
J Biol Chem
, vol.283
, pp. 11689-11699
-
-
Stoecklin, G.1
Tenenbaum, S.A.2
Mayo, T.3
Chittur, S.V.4
George, A.D.5
Baroni, T.E.6
Blackshear, P.J.7
Anderson, P.8
-
122
-
-
0035930565
-
HuA and tristetraprolin are induced following T cell activation and display distinct overlapping RNA binding specificities
-
11602610
-
A Raghavan R Robinson J McNabb C Miller D Williams P Bohjanen 2001 HuA and tristetraprolin are induced following T cell activation and display distinct overlapping RNA binding specificities J Biol Chem 276 47958 47965 11602610
-
(2001)
J Biol Chem
, vol.276
, pp. 47958-47965
-
-
Raghavan, A.1
Robinson, R.2
McNabb, J.3
Miller, C.4
Williams, D.5
Bohjanen, P.6
-
124
-
-
0036435213
-
Transcriptional and post-transcriptional control of gene expression in inflammation
-
12453467
-
M Kracht J Saklatvala 2002 Transcriptional and post-transcriptional control of gene expression in inflammation Cytokine 20 91 106 12453467
-
(2002)
Cytokine
, vol.20
, pp. 91-106
-
-
Kracht, M.1
Saklatvala, J.2
-
125
-
-
0032516626
-
Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin
-
E Carbello W Lai P Blackshear 1998 Feedback inhibition of macrophage tumor necrosis factor-α production by tristetraprolin Science 281 1001 1005
-
(1998)
Science
, vol.281
, pp. 1001-1005
-
-
Carbello, E.1
Lai, W.2
Blackshear, P.3
-
126
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
10204494
-
D Kontoyiannis M Pasparakis TT Pizarro F Cominelli G Kollias 1999 Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies Immunity 10 387 398 10204494
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
127
-
-
4043061488
-
Selective cytoplasmic translocation of HuR and site-specific binding to the interleukin-2 mRNA are not sufficient for CD28-mediated stabilization of the mRNA
-
15020598
-
Y Seko H Azmi R Fariss JA Ragheb 2004 Selective cytoplasmic translocation of HuR and site-specific binding to the interleukin-2 mRNA are not sufficient for CD28-mediated stabilization of the mRNA J Biol Chem 279 33359 33367 15020598
-
(2004)
J Biol Chem
, vol.279
, pp. 33359-33367
-
-
Seko, Y.1
Azmi, H.2
Fariss, R.3
Ragheb, J.A.4
-
128
-
-
0032546972
-
Stabilization of IL-2 mRNA by the c-jun NH2-terminal kinase pathway
-
9632395
-
C Chen F Del Gatto-Konczak Z Wu M Karin 1998 Stabilization of IL-2 mRNA by the c-jun NH2-terminal kinase pathway Science 280 1945 1949 9632395
-
(1998)
Science
, vol.280
, pp. 1945-1949
-
-
Chen, C.1
Del Gatto-Konczak, F.2
Wu, Z.3
Karin, M.4
-
129
-
-
0034657357
-
Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation
-
10817758
-
C Chen R Gherzi J Andersen G Gaietta K Jurchott H Royer M Mann M Karin 2000 Nucleolin and YB-1 are required for JNK-mediated interleukin-2 mRNA stabilization during T-cell activation Genes Dev 14 1236 1248 10817758
-
(2000)
Genes Dev
, vol.14
, pp. 1236-1248
-
-
Chen, C.1
Gherzi, R.2
Andersen, J.3
Gaietta, G.4
Jurchott, K.5
Royer, H.6
Mann, M.7
Karin, M.8
-
130
-
-
0032531907
-
C-jun N-terminal kinase is involved in AUUUA-mediated IL-3 mRNA turnover in mast cells
-
9774347
-
X Ming M Kaiser C Moroni 1998 c-jun N-terminal kinase is involved in AUUUA-mediated IL-3 mRNA turnover in mast cells EMBO J 17 6039 6048 9774347
-
(1998)
EMBO J
, vol.17
, pp. 6039-6048
-
-
Ming, X.1
Kaiser, M.2
Moroni, C.3
-
131
-
-
0033568608
-
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase activated protein kinase-2 and an AU-rich region-targeted mechanism
-
10487749
-
R Winzen M Kracht B Ritter A Wilheim C Chen A Shyu M Muller M Gaestel K Resch H Holtmann 1999 The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase activated protein kinase-2 and an AU-rich region-targeted mechanism EMBO J 18 4969 4980 10487749
-
(1999)
EMBO J
, vol.18
, pp. 4969-4980
-
-
Winzen, R.1
Kracht, M.2
Ritter, B.3
Wilheim, A.4
Chen, C.5
Shyu, A.6
Muller, M.7
Gaestel, M.8
Resch, K.9
Holtmann, H.10
-
132
-
-
0034816062
-
Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability
-
11533235
-
K Mahtani M Brook J Dean G Sully J Saklatvala A Clark 2001 Mitogen-activated protein kinase p38 controls the expression and posttranslational modification of tristetraprolin, a regulator of tumor necrosis factor alpha mRNA stability Mol Cell Biol 21 6461 6469 11533235
-
(2001)
Mol Cell Biol
, vol.21
, pp. 6461-6469
-
-
Mahtani, K.1
Brook, M.2
Dean, J.3
Sully, G.4
Saklatvala, J.5
Clark, A.6
-
133
-
-
26444547693
-
Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA
-
15908450
-
J Mestas SP Crampton T Hori CC Hughes 2005 Endothelial cell co-stimulation through OX40 augments and prolongs T cell cytokine synthesis by stabilization of cytokine mRNA Int Immunol 17 737 747 15908450
-
(2005)
Int Immunol
, vol.17
, pp. 737-747
-
-
Mestas, J.1
Crampton, S.P.2
Hori, T.3
Hughes, C.C.4
-
134
-
-
33644753147
-
Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element
-
16508014
-
E Hitti T Iakovleva M Brook S Deppenmeier AD Gruber D Radzioch AR Clark PJ Blackshear A Kotlyarov M Gaestel 2006 Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich element Mol Cell Biol 26 2399 2407 16508014
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2399-2407
-
-
Hitti, E.1
Iakovleva, T.2
Brook, M.3
Deppenmeier, S.4
Gruber, A.D.5
Radzioch, D.6
Clark, A.R.7
Blackshear, P.J.8
Kotlyarov, A.9
Gaestel, M.10
-
135
-
-
20444414937
-
Structure/function analysis of tristetraprolin (TTP): P38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function
-
15944294
-
WF Rigby K Roy J Collins S Rigby JE Connolly DB Bloch SA Brooks 2005 Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function J Immunol 174 7883 7893 15944294
-
(2005)
J Immunol
, vol.174
, pp. 7883-7893
-
-
Rigby, W.F.1
Roy, K.2
Collins, J.3
Rigby, S.4
Connolly, J.E.5
Bloch, D.B.6
Brooks, S.A.7
-
139
-
-
0035885004
-
CD28 is not required for c-Jun N-terminal kinase activation in T cells
-
11544297
-
F Rivas S O'Herrin T Gajewski 2001 CD28 is not required for c-Jun N-terminal kinase activation in T cells J Immunol 167 3123 3128 11544297
-
(2001)
J Immunol
, vol.167
, pp. 3123-3128
-
-
Rivas, F.1
O'Herrin, S.2
Gajewski, T.3
-
141
-
-
0027983799
-
Purification by DNA affintiy chromatography of two polypeptides that contact the NFAT DNA binding site in the IL-2 promoter
-
8051169
-
B Corthesy P Kao 1994 Purification by DNA affintiy chromatography of two polypeptides that contact the NFAT DNA binding site in the IL-2 promoter J Biol Chem 269 20682 20690 8051169
-
(1994)
J Biol Chem
, vol.269
, pp. 20682-20690
-
-
Corthesy, B.1
Kao, P.2
-
142
-
-
0036924040
-
Nuclear export of NF90 is required for interleukin-2 mRNA stabilization
-
12504009
-
J Shim H Lim J Yates M Karin 2002 Nuclear export of NF90 is required for interleukin-2 mRNA stabilization Mol Cell 10 1331 1344 12504009
-
(2002)
Mol Cell
, vol.10
, pp. 1331-1344
-
-
Shim, J.1
Lim, H.2
Yates, J.3
Karin, M.4
-
143
-
-
34249063242
-
NF90 regulates inducible IL-2 gene expression in T cells
-
17470640
-
L Shi WR Godfrey J Lin G Zhao PN Kao 2007 NF90 regulates inducible IL-2 gene expression in T cells J Exp Med 204 971 977 17470640
-
(2007)
J Exp Med
, vol.204
, pp. 971-977
-
-
Shi, L.1
Godfrey, W.R.2
Lin, J.3
Zhao, G.4
Kao, P.N.5
|