Interleukin 2, but not other common γ chain-binding cytokines, can reverse the defect in generation of CD4 effector T cells from naive T cells of aged mice

Journal of Experimental Medicine

Volumn 190, Issue 7, 1999, Pages 1013-1023

  Haynes, Laura ^a   Linton, Phyllis Jean ^b   Eaton, Sheri M ^a   Tonkonogy, Susan L ^c   Swain, Susan L ^a  

^a TRUDEAU INSTITUTE   (United States)

^b SIDNEY KIMMEL CANCER CENTER   (United States)

^c NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

c binding cytokines; Aging; CD4 cells; IL 2; T cell receptor transgenic

Indexed keywords

CYTOKINE; INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 7;

AGED; AGING; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; HELPER CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; TRANSGENIC MOUSE;

AGING; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOKINES; H-2 ANTIGENS; INTERFERON TYPE II; INTERFERON-GAMMA, RECOMBINANT; INTERLEUKIN-2; INTERLEUKIN-4; INTERLEUKIN-5; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT PROTEINS; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS;

EID: 0033523712     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.190.7.1013     Document Type: Article

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