Novel recognition mode between Vav and Grb2 SH3 domains

EMBO Journal

Volumn 20, Issue 12, 2001, Pages 2995-3007

  Nishida, Motohiko ^a,b   Nagata, Koji ^c   Hachimori, Yukiko ^c   Horiuchi, Masataka ^a   Ogura, Kenji ^a   Mandiyan, Valsan ^d   Schlessinger, Joseph ^d   Inagaki, Fuyuhiko ^a,b  

^a HOKKAIDO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c TOKYO METROPOLITAN INSTITUTE OF MEDICAL SCIENCE   (Japan)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Crystal structure; Growth factor receptor bound protein 2; Protein protein interaction; Srchomology 3 domain; Vav

Indexed keywords

GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROLINE DERIVATIVE; RAC PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; VAV PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CRYSTAL STRUCTURE; DIMERIZATION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL CYCLE PROTEINS; CRYSTALLOGRAPHY, X-RAY; GRB2 ADAPTOR PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PEPTIDES; PROLINE; PROTEIN STRUCTURE, SECONDARY; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-VAV; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SRC HOMOLOGY DOMAINS;

EID: 0035876136     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.12.2995     Document Type: Article

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