Prostaglandin H synthase: Resolved and unresolved mechanistic issues

Archives of Biochemistry and Biophysics

Volumn 493, Issue 1, 2010, Pages 103-124

  Tsai, Ah Lim ^a   Kulmacz, Richard J ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

Arachidonic acid radical; EPR; Hemeprotein; Mechanism; Prostaglandin H synthase; Self activation; Self inactivation; Tyrosyl radical

Indexed keywords

ARACHIDONIC ACID; FATTY ACID; HEME; NITRIC OXIDE; OXYGEN; PEROXIDASE; PEROXIDE; PROSTAGLANDIN SYNTHASE; TYROSINE;

BINDING KINETICS; CATALYSIS; ELECTRON SPIN RESONANCE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME REGULATION; ENZYME STRUCTURE; PRIORITY JOURNAL; REVIEW; STEADY STATE; THERMODYNAMICS;

BIOCATALYSIS; ELECTRON SPIN RESONANCE SPECTROSCOPY; KINETICS; MODELS, MOLECULAR; PEROXIDASES; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROTEIN CONFORMATION;

EID: 72049111244     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2009.08.019     Document Type: Review

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