메뉴 건너뛰기




Volumn 110, Issue 5-6, 2003, Pages 265-268

Variants of cyclooxygenase-1 and their roles in medicine

Author keywords

Acetaminophen; COX 3; PCOX

Indexed keywords

ACETYLSALICYLIC ACID; ANTIBODY; ANTIPYRETIC ANALGESIC AGENT; CYCLOOXYGENASE 1; CYCLOOXYGENASE 3; DICLOFENAC; DIPYRONE; HEME; IBUPROFEN; LIPOPOLYSACCHARIDE; NONSTEROID ANTIINFLAMMATORY AGENT; OXIDIZING AGENT; PARACETAMOL; PHENACETIN; PROSTAGLANDIN; PROSTAGLANDIN SYNTHASE; TUNICAMYCIN; UNCLASSIFIED DRUG;

EID: 0142258064     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(03)00380-3     Document Type: Conference Paper
Times cited : (58)

References (16)
  • 1
    • 0025754779 scopus 로고
    • Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
    • April 1
    • Xie W.L., Chipman J.G., Robertson D.L., Erikson R.L., Simmons D.L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. U. S. A. 88:1991 (April 1);2692-2696.
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 2692-2696
    • Xie, W.L.1    Chipman, J.G.2    Robertson, D.L.3    Erikson, R.L.4    Simmons, D.L.5
  • 2
    • 0025871150 scopus 로고
    • TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
    • Kujubu D.A., Fletcher B.S., Varnum B.C., Lim R.W., Herschman H.R. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem. 266:1991;12866-12872.
    • (1991) J. Biol. Chem. , vol.266 , pp. 12866-12872
    • Kujubu, D.A.1    Fletcher, B.S.2    Varnum, B.C.3    Lim, R.W.4    Herschman, H.R.5
  • 3
    • 0026588961 scopus 로고
    • Mitogen-inducible prostaglandin G/H synthase: A new target for nonsteroidal anti-inflammatory
    • Xie W., Robertson D.L., Simmons D.L. Mitogen-inducible prostaglandin G/H synthase: a new target for nonsteroidal anti-inflammatory. Drug Dev. Res. 25:1992;249-265.
    • (1992) Drug Dev. Res. , vol.25 , pp. 249-265
    • Xie, W.1    Robertson, D.L.2    Simmons, D.L.3
  • 4
    • 0027162479 scopus 로고
    • Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog
    • Xie W., Merrill J.R., Bradshaw W.S., Simmons D.L. Structural determination and promoter analysis of the chicken mitogen-inducible prostaglandin G/H synthase gene and genetic mapping of the murine homolog. Arch. Biochem. Biophys. 300:1993;247-252.
    • (1993) Arch. Biochem. Biophys. , vol.300 , pp. 247-252
    • Xie, W.1    Merrill, J.R.2    Bradshaw, W.S.3    Simmons, D.L.4
  • 5
    • 0026702494 scopus 로고
    • Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
    • Fletcher B.S., Kujubu D.A., Perrin D.M., Herschman H.R. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J. Biol. Chem. 267:1992;4338-4344.
    • (1992) J. Biol. Chem. , vol.267 , pp. 4338-4344
    • Fletcher, B.S.1    Kujubu, D.A.2    Perrin, D.M.3    Herschman, H.R.4
  • 6
    • 0024818522 scopus 로고
    • Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme
    • Yokoyama C., Tanabe T. Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem. Biophys. Res. Commun. 165:1989;888-894.
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 888-894
    • Yokoyama, C.1    Tanabe, T.2
  • 7
    • 0037108979 scopus 로고    scopus 로고
    • COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: Cloning, structure, and expression
    • Chandrasekharan N.V., Dai H., Roos K.L., Evanson N.K., Tomsik J., Elton T.S.et al. COX-3, a cyclooxygenase-1 variant inhibited by acetaminophen and other analgesic/antipyretic drugs: cloning, structure, and expression. Proc. Natl. Acad. Sci. U. S. A. 99:2002;13926-13931.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 13926-13931
    • Chandrasekharan, N.V.1    Dai, H.2    Roos, K.L.3    Evanson, N.K.4    Tomsik, J.5    Elton, T.S.6
  • 8
    • 0015511847 scopus 로고
    • Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol)
    • Flower R.J., Vane J.R. Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature. 240:1972;410-411.
    • (1972) Nature , vol.240 , pp. 410-411
    • Flower, R.J.1    Vane, J.R.2
  • 9
    • 0035866579 scopus 로고    scopus 로고
    • Mechanism of acetaminophen inhibition of cyclooxygenase isoforms
    • Ouellet M., Percival M.D. Mechanism of acetaminophen inhibition of cyclooxygenase isoforms. Arch. Biochem. Biophys. 387:2001;273-280.
    • (2001) Arch. Biochem. Biophys. , vol.387 , pp. 273-280
    • Ouellet, M.1    Percival, M.D.2
  • 10
    • 0020552581 scopus 로고
    • Effects of aspirin, indomethacin, flufenamic acid and paracetamol on prostaglandin output from rat stomach and renal papilla in vitro and ex vivo
    • Danon A., Leibson V., Assouline G. Effects of aspirin, indomethacin, flufenamic acid and paracetamol on prostaglandin output from rat stomach and renal papilla in vitro and ex vivo. J. Pharm. Pharmacol. 35:1983;576-579.
    • (1983) J. Pharm. Pharmacol. , vol.35 , pp. 576-579
    • Danon, A.1    Leibson, V.2    Assouline, G.3
  • 12
    • 0037293488 scopus 로고    scopus 로고
    • Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells
    • Sciulli M.G., Seta F., Tacconelli S., Capone M.L., Ricciotti E., Pistritto G.et al. Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells. Br. J. Pharmacol. 138:2003;634-641.
    • (2003) Br. J. Pharmacol. , vol.138 , pp. 634-641
    • Sciulli, M.G.1    Seta, F.2    Tacconelli, S.3    Capone, M.L.4    Ricciotti, E.5    Pistritto, G.6
  • 13
  • 14
    • 0033013466 scopus 로고    scopus 로고
    • Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs
    • Simmons D.L., Botting R.M., Robertson P.M., Madsen M.L., Vane J.R. Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs. Proc. Natl. Acad. Sci. U. S. A. 96:1999;3275-3280.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 3275-3280
    • Simmons, D.L.1    Botting, R.M.2    Robertson, P.M.3    Madsen, M.L.4    Vane, J.R.5
  • 15
    • 0033841593 scopus 로고    scopus 로고
    • Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E(2) synthesis in rat microglial cells
    • Fiebich B.L., Lieb K., Hull M., Aicher B., van Ryn J., Pairet M.et al. Effects of caffeine and paracetamol alone or in combination with acetylsalicylic acid on prostaglandin E(2) synthesis in rat microglial cells. Neuropharmacology. 39:2000;2205-2213.
    • (2000) Neuropharmacology , vol.39 , pp. 2205-2213
    • Fiebich, B.L.1    Lieb, K.2    Hull, M.3    Aicher, B.4    Van Ryn, J.5    Pairet, M.6
  • 16
    • 0037443693 scopus 로고    scopus 로고
    • Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase
    • Greco A., Ajmone-Cat M.A., Nicolini A., Sciulli M.G., Minghetti L. Paracetamol effectively reduces prostaglandin E2 synthesis in brain macrophages by inhibiting enzymatic activity of cyclooxygenase but not phospholipase and prostaglandin E synthase. J. Neurosci. Res. 71:2003;844-852.
    • (2003) J. Neurosci. Res. , vol.71 , pp. 844-852
    • Greco, A.1    Ajmone-Cat, M.A.2    Nicolini, A.3    Sciulli, M.G.4    Minghetti, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.