The Met-Tyr-Trp cross-link in Mycobacterium tuberculosis catalase-peroxidase (KatG): Autocatalytic formation and effect on enzyme catalysis and spectroscopic properties

Journal of Biological Chemistry

Volumn 280, Issue 24, 2005, Pages 22651-22663

  Ghiladi, Reza A ^a   Knudsen, Giselle M ^a   Medzihradszky, Katalin F ^a   Ortiz De Montellano, Paul R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CROSSLINKING; CRYSTAL STRUCTURE; DISEASE CONTROL; LIQUID CHROMATOGRAPHY; ORGANIC ACIDS; OXIDATION; ULTRAVIOLET SPECTROSCOPY;

BIFUNCTIONAL ENZYMES; CATALASE-PEROXIDASE (KATG); PEPTIDE FRAGMENTS; PERACID; PEROXYACETIC ACID (PAA);

ENZYMES;

2 METHYL 1 PHENYL 2 PROPYL HYDROPEROXIDE; CATALASE; HYDROPEROXIDE; KATG PROTEIN; METHIONINE; PERACETIC ACID; PEROXIDASE; TRYPTOPHAN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CROSS LINKING; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; SPECTROSCOPY;

AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BINDING SITES; CATALASE; CATALYSIS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; HEME; HYDROGEN PEROXIDE; KINETICS; MASS SPECTROMETRY; METHIONINE; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; PERACETIC ACID; PLASMIDS; PROTEIN BINDING; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; TIME FACTORS; TRYPSIN; TRYPTOPHAN; TYROSINE; ULTRAVIOLET RAYS;

MYCOBACTERIUM TUBERCULOSIS;

EID: 20744456284     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M502486200     Document Type: Article

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