-
1
-
-
0015237292
-
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
-
Vane, J. R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature New. Biol., 231: 232-235, 1971
-
(1971)
Nature New. Biol
, vol.231
, pp. 232-235
-
-
Vane, J.R.1
-
2
-
-
0027146692
-
Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase
-
Mitchell, J. A., Akarasereenont, P., Thiemermann, C., Flower, R. J., and Vane, J. R. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase. Proc. Natl. Acad. Sci. USA, 90: 11693-11697, 1994
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 11693-11697
-
-
Mitchell, J.A.1
Akarasereenont, P.2
Thiemermann, C.3
Flower, R.J.4
Vane, J.R.5
-
3
-
-
0024818522
-
Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme
-
Yokoyama, C., and Tanabe, T. Cloning of human gene encoding prostaglandin endoperoxide synthase and primary structure of the enzyme. Biochem. Biophys. Res. Commun., 165: 888-894, 1989
-
(1989)
Biochem. Biophys. Res. Commun
, vol.165
, pp. 888-894
-
-
Yokoyama, C.1
Tanabe, T.2
-
4
-
-
0028226265
-
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2
-
Kosaka, T., Miyata, A., Ihara, H., Hara, S., Sugimoto, T., Takeda, O., Takahashi, E., and Tanabe, T. Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2. Eur. J. Biochem., 221: 889-897, 1994
-
(1994)
Eur. J. Biochem
, vol.221
, pp. 889-897
-
-
Kosaka, T.1
Miyata, A.2
Ihara, H.3
Hara, S.4
Sugimoto, T.5
Takeda, O.6
Takahashi, E.7
Tanabe, T.8
-
5
-
-
0011291543
-
On the mechanism of the biosynthesis of prostaglandins
-
S. Bergström and B. Samuelsson (eds.). Stockholm: Almqvist & Wiksell
-
Samuelsson, B., Granström, E., and Hamberg, M. On the mechanism of the biosynthesis of prostaglandins. In: S. Bergström and B. Samuelsson (eds.), Nobel Symposium 2, Prostaglandins pp. 31-44. Stockholm: Almqvist & Wiksell, 1967
-
(1967)
Nobel Symposium 2, Prostaglandins
, pp. 31-44
-
-
Samuelsson, B.1
Granström, E.2
Hamberg, M.3
-
6
-
-
0017094438
-
Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme
-
Hemler, M., Lands, W. E. M., and Smith, W. L. Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme. J. Biol. Chem., 251: 5575-5579, 1976
-
(1976)
J. Biol. Chem
, vol.251
, pp. 5575-5579
-
-
Hemler, M.1
Lands, W.E.M.2
Smith, W.L.3
-
7
-
-
0017070560
-
Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes
-
Miyamoto, T., Ogino, N., Yamamoto, S., and Hayalshi, O. Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes. J. Biol. Chem., 251: 2629-2636, 1976
-
(1976)
J. Biol. Chem
, vol.251
, pp. 2629-2636
-
-
Miyamoto, T.1
Ogino, N.2
Yamamoto, S.3
Hayalshi, O.4
-
8
-
-
0025754779
-
Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing
-
Xie, W., Chipman, J. G., Robertson, D. L., Erikson, R. L., and Simmons, D. L. Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing. Proc. Natl. Acad. Sci. USA, 88: 2692-2696, 1991
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2692-2696
-
-
Xie, W.1
Chipman, J.G.2
Robertson, D.L.3
Erikson, R.L.4
Simmons, D.L.5
-
9
-
-
0025871150
-
TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue
-
Kujubu, D. A., Fletcher, B. S., Varnum, B. C., Lim, R. W., and Herschman, H. R. TIS10, a phorbol ester tumor promoter-inducible mRNA from Swiss 3T3 cells, encodes a novel prostaglandin synthase/cyclooxygenase homologue. J. Biol. Chem., 266: 12866-12872, 1991
-
(1991)
J. Biol. Chem
, vol.266
, pp. 12866-12872
-
-
Kujubu, D.A.1
Fletcher, B.S.2
Varnum, B.C.3
Lim, R.W.4
Herschman, H.R.5
-
10
-
-
0026322957
-
A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein
-
O'Banion, M. K., Sadowski, H. B., Winn, V., and Young, D. A. A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein. J. Biol. Chem., 266: 23261-23267, 1991
-
(1991)
J. Biol. Chem
, vol.266
, pp. 23261-23267
-
-
O'Banion, M.K.1
Sadowski, H.B.2
Winn, V.3
Young, D.A.4
-
11
-
-
0032540344
-
Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy
-
Spencer, A. G., Woods, J. W., Arakawa, T., Singer, I. I., and Smith, W. L. Subcellular localization of prostaglandin endoperoxide H synthases-1 and -2 by immunoelectron microscopy. J. Biol. Chem., 273: 9886-9893, 1998
-
(1998)
J. Biol. Chem
, vol.273
, pp. 9886-9893
-
-
Spencer, A.G.1
Woods, J.W.2
Arakawa, T.3
Singer, I.I.4
Smith, W.L.5
-
12
-
-
0027993458
-
Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocaminomas
-
Eberhart, C. E., Coffey, R. J., Radhika, A., Giardiello, F. M., Ferrenbach, S., and DuBois, R. N. Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocaminomas. Gastroenterology, 107: 1183-1188, 1994
-
(1994)
Gastroenterology
, vol.107
, pp. 1183-1188
-
-
Eberhart, C.E.1
Coffey, R.J.2
Radhika, A.3
Giardiello, F.M.4
Ferrenbach, S.5
DuBois, R.N.6
-
13
-
-
0029117472
-
Expression of cyclooxygenase-1 and -2 in human colorectal cancer
-
Sano, H., Kawahito, Y., Wilder, R. L., Hashiramoto, A., Mukai, S., Asai, K., Kimura, S., Kato, H., Kondo, M., and Hla, T. Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Res., 55: 3785-3789, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 3785-3789
-
-
Sano, H.1
Kawahito, Y.2
Wilder, R.L.3
Hashiramoto, A.4
Mukai, S.5
Asai, K.6
Kimura, S.7
Kato, H.8
Kondo, M.9
Hla, T.10
-
14
-
-
0029008617
-
Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer
-
Kargman, S. L., O'Neill, G. P., Vickers, P. J., Evans, J. F., Mancini, J. A., and Jothy, S. Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Res., 55: 2556-2559, 1995
-
(1995)
Cancer Res
, vol.55
, pp. 2556-2559
-
-
Kargman, S.L.1
O'Neill, G.P.2
Vickers, P.J.3
Evans, J.F.4
Mancini, J.A.5
Jothy, S.6
-
15
-
-
0029899153
-
Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: Evidence for a transcriptional effect
-
Kutchera, W., Jones, D. A., Matsunami, N., Groden, J., McIntyre, T. M., Zimmerman, G. A., White, R. L., and Prescott, S. M. Prostaglandin H synthase 2 is expressed abnormally in human colon cancer: Evidence for a transcriptional effect. Proc. Natl. Acad. Sci. USA, 93: 4816-4820, 1996
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 4816-4820
-
-
Kutchera, W.1
Jones, D.A.2
Matsunami, N.3
Groden, J.4
McIntyre, T.M.5
Zimmerman, G.A.6
White, R.L.7
Prescott, S.M.8
-
16
-
-
0032212487
-
Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas
-
Fujita, T., Matsui, M., Takaku, K., Uetake, H., Ichikawa, W., Taketo, M. M., and Sugihara, K. Size- and invasion-dependent increase in cyclooxygenase 2 levels in human colorectal carcinomas. Cancer Res., 58: 4823-4826, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 4823-4826
-
-
Fujita, T.1
Matsui, M.2
Takaku, K.3
Uetake, H.4
Ichikawa, W.5
Taketo, M.M.6
Sugihara, K.7
-
17
-
-
0030606299
-
Δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)
-
Δ716 knockout mice by inhibition of cyclooxygenase 2 (COX-2). Cell, 87: 803-309, 1996
-
(1996)
Cell
, vol.87
, pp. 803-309
-
-
Oshima, M.1
Dinchuk, J.E.2
Kargman, S.L.3
Oshima, H.4
Hancock, B.5
Kwong, E.6
Trzaskos, J.M.7
Evans, J.F.8
Taketo, M.M.9
-
18
-
-
0032006784
-
Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis
-
Kawamori, T., Rao, C. V., Seibert, K., and Reddy, B. S. Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis. Cancer Res., 58: 409-412, 1998
-
(1998)
Cancer Res
, vol.58
, pp. 409-412
-
-
Kawamori, T.1
Rao, C.V.2
Seibert, K.3
Reddy, B.S.4
-
19
-
-
0034665122
-
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the Min mouse model of adenomatous polyposis
-
Jacoby, R. F., Seibert, K., Cole, C. E., Kelloff, G., and Lubet, R. A. The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the Min mouse model of adenomatous polyposis. Cancer Res., 60: 5040-5044, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 5040-5044
-
-
Jacoby, R.F.1
Seibert, K.2
Cole, C.E.3
Kelloff, G.4
Lubet, R.A.5
-
20
-
-
0038543824
-
Chemoprevention of colorectal cancer
-
Jänne, P. A., and Mayer, R. J. Chemoprevention of colorectal cancer. N. Engl. J. Med., 342: 1960-1968, 2000
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 1960-1968
-
-
Jänne, P.A.1
Mayer, R.J.2
-
21
-
-
17744418769
-
The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis
-
Steinbach, G., Lynch, P. M., Phillips, R. K. S., Wallace, M. H., Hawk, E., Gordon, G. B., Wakabayashi, N., Saunders, B., Shen, Y., Fujimura, T., Su, L-K., and Levin, B. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N. Engl. J. Med. 342: 1946-1952, 2000
-
(2000)
N. Engl. J. Med
, vol.342
, pp. 1946-1952
-
-
Steinbach, G.1
Lynch, P.M.2
Phillips, R.K.S.3
Wallace, M.H.4
Hawk, E.5
Gordon, G.B.6
Wakabayashi, N.7
Saunders, B.8
Shen, Y.9
Fujimura, T.10
Su, L.-K.11
Levin, B.12
-
22
-
-
0023687241
-
Colorectal cancer risk, chronic illnesses, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study
-
Kune, G. A., Kune, S., Watson, L. F. Colorectal cancer risk, chronic illnesses, operations, and medications: Case control results from the Melbourne Colorectal Cancer Study. Cancer Res., 48: 4399-4404, 1988
-
(1988)
Cancer Res
, vol.48
, pp. 4399-4404
-
-
Kune, G.A.1
Kune, S.2
Watson, L.F.3
-
23
-
-
0031888471
-
Aspirin and nonsteroidal anti-inflammatory agents and risk for colorectal adenomas
-
Sandler, R. S., Galanko, J. C., Murray, S. C., Helm, J. F., and Woosley, J. T. Aspirin and nonsteroidal anti-inflammatory agents and risk for colorectal adenomas. Gastroenterology, 114: 441-447, 1998
-
(1998)
Gastroenterology
, vol.114
, pp. 441-447
-
-
Sandler, R.S.1
Galanko, J.C.2
Murray, S.C.3
Helm, J.F.4
Woosley, J.T.5
-
25
-
-
0027433113
-
Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: Evidence for solvent-induced bends in DNA heteroduplexes
-
Ganguly, A., Rock, M. J., and Prockop, D. J. Conformation-sensitive gel electrophoresis for rapid detection of single-base differences in double-stranded PCR products and DNA fragments: Evidence for solvent-induced bends in DNA heteroduplexes. Proc. Natl. Acad. Sci. USA, 90: 10325-10329, 1993
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10325-10329
-
-
Ganguly, A.1
Rock, M.J.2
Prockop, D.J.3
-
26
-
-
0028912181
-
Three new point mutations in type II procollagen (COL2A1) and identification of a fourth family with the COL2A1 Arg519→Cys base substitution using conformation sensitive gel electrophoresis
-
Williams, C. J., Rock, M., Considine, E., McCarron, S., Gow, P., Ladda, R., McLain, D., Michels, V. M., Murphy, W., Prockop, D. J., and Ganguly, A. Three new point mutations in type II procollagen (COL2A1) and identification of a fourth family with the COL2A1 Arg519→Cys base substitution using conformation sensitive gel electrophoresis. Hum. Mol. Genet., 4: 309-312, 1995
-
(1995)
Hum. Mol. Genet
, vol.4
, pp. 309-312
-
-
Williams, C.J.1
Rock, M.2
Considine, E.3
McCarron, S.4
Gow, P.5
Ladda, R.6
McLain, D.7
Michels, V.M.8
Murphy, W.9
Prockop, D.J.10
Ganguly, A.11
-
27
-
-
7144226607
-
Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas
-
Lin, H. J., Probst-Hensch, N. M., Hughes, N. C., Sakamoto, G. T., Louie, A. D., Kau, I. H., Lin, B. K., Lee, D. B., Lin, J., Frankl, H., D., Lee, E. R., Hardy, S., Grant, D. M., and Haile, R. W. Variants of N-acetyltransferase NAT1 and a case-control study of colorectal adenomas. Pharmacogenetics, 8: 269-281, 1998
-
(1998)
Pharmacogenetics
, vol.8
, pp. 269-281
-
-
Lin, H.J.1
Probst-Hensch, N.M.2
Hughes, N.C.3
Sakamoto, G.T.4
Louie, A.D.5
Kau, I.H.6
Lin, B.K.7
Lee, D.B.8
Lin, J.9
Frankl, H.D.10
Lee, E.R.11
Hardy, S.12
Grant, D.M.13
Haile, R.W.14
-
28
-
-
0027986841
-
Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-Inflammatory drugs
-
Laneuville, O., Breuer, D. K., DeWitt, D. L., Hla, T., Funk, C. D., and Smith, W. L. Differential inhibition of human prostaglandin endoperoxide H synthases-1 and -2 by nonsteroidal anti-Inflammatory drugs. J. Pharmacol. Exp. Ther., 271: 927-934, 1994
-
(1994)
J. Pharmacol. Exp. Ther
, vol.271
, pp. 927-934
-
-
Laneuville, O.1
Breuer, D.K.2
DeWitt, D.L.3
Hla, T.4
Funk, C.D.5
Smith, W.L.6
-
29
-
-
0028339780
-
Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin
-
Lecomte, M., Laneuville, O., Ji, C., DeWitt, D. L., and Smith, W. L. Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin. J. Biol. Chem., 269: 13207-13215, 1994
-
(1994)
J. Biol. Chem
, vol.269
, pp. 13207-13215
-
-
Lecomte, M.1
Laneuville, O.2
Ji, C.3
DeWitt, D.L.4
Smith, W.L.5
-
30
-
-
0026704175
-
Prostaglandin endoperoxide synthase. The aspirin acetylation region
-
Shimokawa, T., and Smith, W. L. Prostaglandin endoperoxide synthase. The aspirin acetylation region. J. Biol. Chem., 267: 12387-12392, 1992
-
(1992)
J. Biol. Chem
, vol.267
, pp. 12387-12392
-
-
Shimokawa, T.1
Smith, W.L.2
-
31
-
-
0027609916
-
SETOR hardware-lighted three-dimensional solid model representations of macromolecules
-
Evans, S. V. SETOR: hardware-lighted three-dimensional solid model representations of macromolecules. J. Mol. Graphics, 11: 134-138, 127-128, 1993
-
(1993)
J. Mol. Graphics
, vol.11
, pp. 134-138
-
-
Evans, S.V.1
-
32
-
-
0029911267
-
Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2
-
Luong, C., Miller, A., Barnett, J., Chow, J., Ramesha, C., and Browner, M. F. Flexibility of the NSAID binding site in the structure of human cyclooxygenase-2. Nat. Struct. Biol., 3: 927-933, 1996
-
(1996)
Nat. Struct. Biol
, vol.3
, pp. 927-933
-
-
Luong, C.1
Miller, A.2
Barnett, J.3
Chow, J.4
Ramesha, C.5
Browner, M.F.6
-
33
-
-
0030461132
-
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
-
Kurumbail, R. G., Stevens, A. M., Gierse, J. K., McDonald, J. J., Stegeman, R. A., Pak, J. Y., Gildehaus D., Miyashiro, J. M., Penning, T. D. Selbert K., Isakson, P. C., and Stalling, W. C. Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature (Lond.), 384: 644-648, 1996
-
(1996)
Nature (Lond.)
, vol.384
, pp. 644-648
-
-
Kurumbail, R.G.1
Stevens, A.M.2
Gierse, J.K.3
McDonald, J.J.4
Stegeman, R.A.5
Pak, J.Y.6
Gildehaus, D.7
Miyashiro, J.M.8
Penning, T.D.9
Selbert, K.10
Isakson, P.C.11
Stallings, W.C.12
-
34
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls, A., Sharp, K. A., and Honig, B. Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins Struct. Funct. Genet., 11: 281-296, 1991
-
(1991)
Proteins Struct. Funct. Genet
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.A.2
Honig, B.3
-
35
-
-
0031438971
-
A sigmoidoscopy-based case-control study of polyps: Macronutrients, fiber and meat consumption
-
Haile, R. W., Witte, J. S., Longnecker, M. P., Probst-Hensch, N., Chen, M-J., Harper, J., Frankl, H. D., and Lee, E. R. A sigmoidoscopy-based case-control study of polyps: Macronutrients, fiber and meat consumption. Int. J. Cancer, 73: 497-502, 1997
-
(1997)
Int. J. Cancer
, vol.73
, pp. 497-502
-
-
Haile, R.W.1
Witte, J.S.2
Longnecker, M.P.3
Probst-Hensch, N.4
Chen, M.-J.5
Harper, J.6
Frankl, H.D.7
Lee, E.R.8
-
36
-
-
18844474648
-
A multiethnic cohort in Hawaii and Los Angeles: Baseline characteristics
-
Kolonel, L. N., Henderson, B. E., Hankin, J. H., Nomura, A. M. Y., Wilkens, L. R., Pike, M. C., Stram, D. O., Monroe, K. R., Earle, M. E., and Nagamine, F. S. A multiethnic cohort in Hawaii and Los Angeles: Baseline characteristics. Am. J. Epidemiol., 151: 346-357, 2000
-
(2000)
Am. J. Epidemiol
, vol.151
, pp. 346-357
-
-
Kolonel, L.N.1
Henderson, B.E.2
Hankin, J.H.3
Nomura, A.M.Y.4
Wilkens, L.R.5
Pike, M.C.6
Stram, D.O.7
Monroe, K.R.8
Earle, M.E.9
Nagamine, F.S.10
-
37
-
-
0023058975
-
A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation
-
Shaw, G., and Kamen, R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell, 46 659-667, 1986
-
(1986)
Cell
, vol.46
, pp. 659-667
-
-
Shaw, G.1
Kamen, R.2
-
38
-
-
0034697027
-
Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3′-untranslated region
-
Dixon, D. A., Kaplan, C. D., McIntyre, T. M., Zimmerman, G. A., and Prescott, S. M. Post-transcriptional control of cyclooxygenase-2 gene expression. The role of the 3′-untranslated region. J. Biol. Chem., 275: 11750-11757, 2000
-
(2000)
J. Biol. Chem
, vol.275
, pp. 11750-11757
-
-
Dixon, D.A.1
Kaplan, C.D.2
McIntyre, T.M.3
Zimmerman, G.A.4
Prescott, S.M.5
-
40
-
-
0034665857
-
The productive conformation of arachidonic acid bound to prostaglandin synthase
-
Malkowski, M. G., Ginell, S. L., Smith, W. L., and Garavito, R. M. The productive conformation of arachidonic acid bound to prostaglandin synthase. Science (Wash. DC), 289: 1933-1937, 2000
-
(2000)
Science (Wash. DC)
, vol.289
, pp. 1933-1937
-
-
Malkowski, M.G.1
Ginell, S.L.2
Smith, W.L.3
Garavito, R.M.4
-
41
-
-
0035971116
-
Prostaglandin endoperoxide H synthase-1. The functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid
-
Thuresson, E. D., Lakkides, K. M., Rieke, C. J., Sun, Y., Wingerd, B. A., Micielli, R., Mulichak, A. M., Malkowski, M. G., Garavito, R. M., and Smith, W. L. Prostaglandin endoperoxide H synthase-1. The functions of cyclooxygenase active site residues in the binding, positioning, and oxygenation of arachidonic acid. J. Biol. Chem., 276: 10347-10359, 2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 10347-10359
-
-
Thuresson, E.D.1
Lakkides, K.M.2
Rieke, C.J.3
Sun, Y.4
Wingerd, B.A.5
Micielli, R.6
Mulichak, A.M.7
Malkowski, M.G.8
Garavito, R.M.9
Smith, W.L.10
-
42
-
-
0034764480
-
Functional characterization of cyclooxygenase-2 polymorphisms
-
Fritsche, E., Baek, S. J., King, L. M., Zeldin, D. C., Eling, T. E., and Bell, D. A. Functional characterization of cyclooxygenase-2 polymorphisms. J. Pharmacol. Exp. Ther., 299: 468-476, 2001
-
(2001)
J. Pharmacol. Exp. Ther
, vol.299
, pp. 468-476
-
-
Fritsche, E.1
Baek, S.J.2
King, L.M.3
Zeldin, D.C.4
Eling, T.E.5
Bell, D.A.6
-
43
-
-
0035374339
-
Selective suppression of CCAAT/enhancer-binding protein β binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts
-
Saunders, M. A., Sansores-Garcia, L., Gilroy, D. W., and Wu, K. K. Selective suppression of CCAAT/enhancer-binding protein β binding and cyclooxygenase-2 promoter activity by sodium salicylate in quiescent human fibroblasts. J. Biol. Chem., 276: 18897-18904, 2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 18897-18904
-
-
Saunders, M.A.1
Sansores-Garcia, L.2
Gilroy, D.W.3
Wu, K.K.4
-
44
-
-
0029149067
-
Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2
-
Laneuville, O., Breuer, D. K., Xu, N., Huang, Z. H., Gage, D. A., Watson, J. T., Legarde, M., DeWitt, D. L., and Smith, W. L. Fatty acid substrate specificities of human prostaglandin-endoperoxide H synthase-1 and -2. J. Biol. Chem., 270: 19330-19336, 1995
-
(1995)
J. Biol. Chem
, vol.270
, pp. 19330-19336
-
-
Laneuville, O.1
Breuer, D.K.2
Xu, N.3
Huang, Z.H.4
Gage, D.A.5
Watson, J.T.6
Legarde, M.7
DeWitt, D.L.8
Smith, W.L.9
-
45
-
-
0028199075
-
Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
-
Reddy, S. T., and Herschman, H. R. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J. Biol. Chem., 269: 15473-15480, 1994
-
(1994)
J. Biol. Chem
, vol.269
, pp. 15473-15480
-
-
Reddy, S.T.1
Herschman, H.R.2
-
47
-
-
0030995430
-
Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid
-
Swinney, D. C., Mak, A. Y., Barnett, J., and Ramesha, C. S. Differential allosteric regulation of prostaglandin H synthase 1 and 2 by arachidonic acid. J. Biol. Chem., 272: 12393-12398, 1997
-
(1997)
J. Biol. Chem
, vol.272
, pp. 12393-12398
-
-
Swinney, D.C.1
Mak, A.Y.2
Barnett, J.3
Ramesha, C.S.4
-
48
-
-
0034708764
-
Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products
-
Thuresson, E. D., Lakkides, K. M., and Smith, W. L. Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products. J. Biol. Chem., 275: 8501-8507, 2000
-
(2000)
J. Biol. Chem
, vol.275
, pp. 8501-8507
-
-
Thuresson, E.D.1
Lakkides, K.M.2
Smith, W.L.3
-
49
-
-
0035971186
-
Mutational and x-ray crystallographic analysis of the interaction of dihomo-γ-linolenic acid with prostaglandin endoperoxide H synthases
-
Thuresson, E. D., Malkowski, M. G., Lakkides, K. M., Rieke, C. J., Mulichak, A. M., Ginell, S. L., Garavito, R. M., and Smith, W. L. Mutational and x-ray crystallographic analysis of the interaction of dihomo-γ-linolenic acid with prostaglandin endoperoxide H synthases. J. Biol. Chem., 276: 10358-10365, 2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 10358-10365
-
-
Thuresson, E.D.1
Malkowski, M.G.2
Lakkides, K.M.3
Rieke, C.J.4
Mulichak, A.M.5
Ginell, S.L.6
Garavito, R.M.7
Smith, W.L.8
-
50
-
-
0035813182
-
Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1
-
Malkowski, M. G., Thuresson, E. D., Lakkides, K. M., Rieke, C. J., Micielli, R., Smith, W. L., and Garavito, M. R. Structure of eicosapentaenoic and linoleic acids in the cyclooxygenase site of prostaglandin endoperoxide H synthase-1. J. Biol. Chem., 276: 37547-37555, 2001
-
(2001)
J. Biol. Chem
, vol.276
, pp. 37547-37555
-
-
Malkowski, M.G.1
Thuresson, E.D.2
Lakkides, K.M.3
Rieke, C.J.4
Micielli, R.5
Smith, W.L.6
Garavito, M.R.7
-
51
-
-
0035906232
-
Testing for colon neoplasia susceptibility variants at the human COX2 locus
-
Wiesner, G. L., Platzer, P., Buxbaum, S., Lewis, S., MacMillen, M., Olechnowicz, J., Willis, J., Chakravarti, A., Elston, R. C., and Markowitz, S. D. Testing for colon neoplasia susceptibility variants at the human COX2 locus. J. Natl. Cancer Inst., 93: 635-639, 2001
-
(2001)
J. Natl. Cancer Inst
, vol.93
, pp. 635-639
-
-
Wiesner, G.L.1
Platzer, P.2
Buxbaum, S.3
Lewis, S.4
MacMillen, M.5
Olechnowicz, J.6
Willis, J.7
Chakravarti, A.8
Elston, R.C.9
Markowitz, S.D.10
-
52
-
-
0030606276
-
Self-promotion? Intimate connections between APC and prostaglandin H synthase-2
-
Prescott, S. M., and White, R. L. Self-promotion? Intimate connections between APC and prostaglandin H synthase-2. Cell. 87: 783-786, 1996
-
(1996)
Cell
, vol.87
, pp. 783-786
-
-
Prescott, S.M.1
White, R.L.2
-
53
-
-
0034796261
-
Δ716 knockout mice
-
Δ716 knockout mice. Nat. Med., 7: 1048-1051, 2001
-
(2001)
Nat. Med
, vol.7
, pp. 1048-1051
-
-
Sonoshita, M.1
Takaku, K.2
Sasaki, N.3
Sugimoto, Y.4
Ushikubi, F.5
Narumiya, S.6
Oshima, M.7
Taketo, M.M.8
-
54
-
-
0006132932
-
Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ
-
Kliewer, S. A., Sundseth, S. S., Jones, S. A., Brown, P. J., Wisely, G. B., Koble, C. S., Devchand, P., Wahli, W., Willson, T. M., Lenhard, J. M., and Lehmann, J. M. Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors α and γ. Proc. Natl. Acad. Sci. USA, 94: 4318-4323, 1997
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 4318-4323
-
-
Kliewer, S.A.1
Sundseth, S.S.2
Jones, S.A.3
Brown, P.J.4
Wisely, G.B.5
Koble, C.S.6
Devchand, P.7
Wahli, W.8
Willson, T.M.9
Lenhard, J.M.10
Lehmann, J.M.11
-
55
-
-
0028972025
-
2 is a ligand for the adipocyte determination factor PPARγ
-
2 is a ligand for the adipocyte determination factor PPARγ. Cell, 83: 803-812, 1995
-
(1995)
Cell
, vol.83
, pp. 803-812
-
-
Forman, B.M.1
Tontonoz, P.2
Chen, J.3
Brun, R.P.4
Spiegelman, B.M.5
Evans, R.M.6
-
56
-
-
0033137322
-
2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells
-
2 induce proliferation of cyclooxygenase-depleted colorectal cancer cells. Cancer Res., 59: 2739-2746, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 2739-2746
-
-
Chinery, R.1
Coffey, R.J.2
Graves-Deal, R.3
Kirkland, S.C.4
Sanchez, S.C.5
Zackert, W.E.6
Oates, J.A.7
Morrow, J.D.8
-
57
-
-
0031667938
-
Activators of the nuclear receptor PPARγ enhance colon polyp formation
-
Fajas, L., Auboeuf, D., Raspé, E., Schoonjans, K., Lefebvre, A-M., Saladin, R., Najib, J., Laville, M., Fruchart, J-C., Deeb, S., Vidal-Puig, A., Flier, J., Briggs, M. R., Staels, B., Vidal, H., and Auwerx, J. Activators of the nuclear receptor PPARγ enhance colon polyp formation. Nat. Med., 4: 1058-1061, 1998
-
(1998)
Nat. Med
, vol.4
, pp. 1058-1061
-
-
Fajas, L.1
Auboeuf, D.2
Raspé, E.3
Schoonjans, K.4
Lefebvre, A.-M.5
Saladin, R.6
Najib, J.7
Laville, M.8
Fruchart, J.-C.9
Deeb, S.10
Vidal-Puig, A.11
Flier, J.12
Briggs, M.R.13
Staels, B.14
Vidal, H.15
Auwerx, J.16
-
58
-
-
0037109043
-
APC-dependent suppression of colon carcinogenesis by PPARγ
-
Gimun, G. D., Smith, W. M., Drori, S., Sarraf, P., Mueller, E., Eng, C., Nambiar, P., Rosenberg, D. W., Bronson, R. T., Edelmann, W., Kucherlapati, R., Gonzalez, F. J., Spiegelman. B. M. APC-dependent suppression of colon carcinogenesis by PPARγ. Proc. Natl. Acad. Sci. USA, 99: 13771-13776, 2002
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13771-13776
-
-
Gimun, G.D.1
Smith, W.M.2
Drori, S.3
Sarraf, P.4
Mueller, E.5
Eng, C.6
Nambiar, P.7
Rosenberg, D.W.8
Bronson, R.T.9
Edelmann, W.10
Kucherlapati, R.11
Gonzalez, F.J.12
Spiegelman, B.M.13
-
60
-
-
0003504049
-
Cyclooxygenase regulates angiogenesis induced by colon cancer cells
-
Tsujii, M., Kawano, S., Tsuji, S., Sawaoka, H., Hori, M., and Dubois, R. N. Cyclooxygenase regulates angiogenesis induced by colon cancer cells. Cell, 93: 705-716, 1998
-
(1998)
Cell
, vol.93
, pp. 705-716
-
-
Tsujii, M.1
Kawano, S.2
Tsuji, S.3
Sawaoka, H.4
Hori, M.5
Dubois, R.N.6
-
61
-
-
0034032244
-
Cyclooxygenase-2, a colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB
-
Ramsay, R. G., Friend, A., Vizantios, Y., Freeman, R., Sicurella, C., Hammett, F., Armes, J., and Venter, D. Cyclooxygenase-2, a colorectal cancer nonsteroidal anti-inflammatory drug target, is regulated by c-MYB. Cancer Res., 60: 1805-1809, 2000
-
(2000)
Cancer Res
, vol.60
, pp. 1805-1809
-
-
Ramsay, R.G.1
Friend, A.2
Vizantios, Y.3
Freeman, R.4
Sicurella, C.5
Hammett, F.6
Armes, J.7
Venter, D.8
-
62
-
-
0034691750
-
Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings
-
Imperiale, T. F., Wagner, D. R., Lin, C. Y., Larkin, G. N., Rogge, J. D., and Ransohoff, D. F. Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings. N. Engl. J. Med., 343: 169-174, 2000
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 169-174
-
-
Imperiale, T.F.1
Wagner, D.R.2
Lin, C.Y.3
Larkin, G.N.4
Rogge, J.D.5
Ransohoff, D.F.6
-
63
-
-
0025743040
-
Flexible sigmoidoscopy may be ineffective for secondary prevention of colorectal cancer in asymptomatic, average-risk men
-
Foutch, P. G., Mai, H., Pardy, K., DiSario, J. A., Manne, R. K., and Kerr, D. Flexible sigmoidoscopy may be ineffective for secondary prevention of colorectal cancer in asymptomatic, average-risk men. Dig. Dis. Sci., 36: 924-928, 1991
-
(1991)
Dig. Dis. Sci
, vol.36
, pp. 924-928
-
-
Foutch, P.G.1
Mai, H.2
Pardy, K.3
DiSario, J.A.4
Manne, R.K.5
Kerr, D.6
-
64
-
-
0031612929
-
Recommendations for a nomenclature system for human gene mutations
-
Antonarakis, S. E., and the Nomenclature Working Group. Recommendations for a nomenclature system for human gene mutations. Hum. Mut., 11: 1-3, 1998
-
(1998)
Hum. Mut
, vol.11
, pp. 1-3
-
-
Antonarakis, S.E.1
|