Structural insights into the stereochemistry of the cyclooxygenase reaction

Nature

Volumn 405, Issue 6782, 2000, Pages 97-101

  Kiefer, James R ^a   Pawiitz, Jennifer L ^a   Moreland, Kirby T ^a   Stegeman, Roderick A ^a   Hood, William F ^a   Glerse, James K ^a   Stevens, Anna M ^a   Goodwin, Douglas C ^b   Rowlinson, Scott W ^b   Marnett, Lawrence J ^b   Stallings, William C ^a   Kurumbail, Ravi G ^a  

^a MONSANTO COMPANY   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; PROSTAGLANDIN G2; PROSTAGLANDIN SYNTHASE;

ARTICLE; CHIRALITY; CRYSTAL STRUCTURE; ENZYME SUBSTRATE COMPLEX; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; STEREOCHEMISTRY;

ANIMALS; APOENZYMES; ARACHIDONIC ACID; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYCLOOXYGENASE 2; ISOENZYMES; MICE; MODELS, MOLECULAR; PROSTAGLANDIN H2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS H; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; STEREOISOMERISM;

EID: 16744369033     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35011103     Document Type: Article

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