-
1
-
-
0036553438
-
Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis
-
Almon R.R., DuBois D.C., Brandenburg E.H., Shi W., Zhang S., Straubinger R.M., et al. Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis. Journal of Pharmacokinetics and Pharmacodynamics 29 2 (2002) 103-129
-
(2002)
Journal of Pharmacokinetics and Pharmacodynamics
, vol.29
, Issue.2
, pp. 103-129
-
-
Almon, R.R.1
DuBois, D.C.2
Brandenburg, E.H.3
Shi, W.4
Zhang, S.5
Straubinger, R.M.6
-
2
-
-
27144451563
-
Pharmacogenomic responses of rat liver to methylprednisolone: An approach to mining a rich microarray time series
-
Almon R.R., Dubois D.C., Jin J.Y., and Jusko W.J. Pharmacogenomic responses of rat liver to methylprednisolone: An approach to mining a rich microarray time series. Aaps Journal 7 1 (2005) E156-E194
-
(2005)
Aaps Journal
, vol.7
, Issue.1
-
-
Almon, R.R.1
Dubois, D.C.2
Jin, J.Y.3
Jusko, W.J.4
-
3
-
-
34249785105
-
A microarray analysis of the temporal response of liver to methylprednisolone: A comparative analysis of two dosing regimens
-
Almon R.R., DuBois D.C., and Jusko W.J. A microarray analysis of the temporal response of liver to methylprednisolone: A comparative analysis of two dosing regimens. Endocrinology 148 5 (2007) 2209-2225
-
(2007)
Endocrinology
, vol.148
, Issue.5
, pp. 2209-2225
-
-
Almon, R.R.1
DuBois, D.C.2
Jusko, W.J.3
-
5
-
-
4744344132
-
In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling
-
An G. In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling. Critical Care Medicine 32 10 (2004) 2050-2060
-
(2004)
Critical Care Medicine
, vol.32
, Issue.10
, pp. 2050-2060
-
-
An, G.1
-
6
-
-
46449119246
-
Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation
-
An G. Introduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammation. Theoretical Biology & Medical Modelling 5 (2008) 11
-
(2008)
Theoretical Biology & Medical Modelling
, vol.5
, pp. 11
-
-
An, G.1
-
7
-
-
41849114552
-
Translational systems biology: Introduction of an engineering approach to the pathophysiology of the burn patient
-
An G., Faeder J., and Vodovotz Y. Translational systems biology: Introduction of an engineering approach to the pathophysiology of the burn patient. Journal of Burn Care & Research 29 2 (2008) 277-285
-
(2008)
Journal of Burn Care & Research
, vol.29
, Issue.2
, pp. 277-285
-
-
An, G.1
Faeder, J.2
Vodovotz, Y.3
-
8
-
-
4344618571
-
Corticosteroids for severe sepsis and septic shock: A systematic review and meta-analysis
-
Annane D., Bellissant E., Bollaert P.E., Briegel J., Keh D., and Kupfer Y. Corticosteroids for severe sepsis and septic shock: A systematic review and meta-analysis. BMJ 329 7464 (2004) 480
-
(2004)
BMJ
, vol.329
, Issue.7464
, pp. 480
-
-
Annane, D.1
Bellissant, E.2
Bollaert, P.E.3
Briegel, J.4
Keh, D.5
Kupfer, Y.6
-
9
-
-
2942738987
-
Corticosteroids for treating severe sepsis and septic shock
-
Annane D., Bellissant E., Bollaert P.E., Briegel J., Keh D., and Kupfer Y. Corticosteroids for treating severe sepsis and septic shock. Cochrane Database Systematic Reviews 1 (2004) CD002243
-
(2004)
Cochrane Database Systematic Reviews
, vol.1
-
-
Annane, D.1
Bellissant, E.2
Bollaert, P.E.3
Briegel, J.4
Keh, D.5
Kupfer, Y.6
-
10
-
-
0037151571
-
Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
-
Annane D., Sebille V., Charpentier C., Bollaert P.E., Francois B., Korach J.M., et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288 7 (2002) 862-871
-
(2002)
JAMA
, vol.288
, Issue.7
, pp. 862-871
-
-
Annane, D.1
Sebille, V.2
Charpentier, C.3
Bollaert, P.E.4
Francois, B.5
Korach, J.M.6
-
11
-
-
0028125787
-
Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following induction by endotoxin
-
Arzt E., Sauer J., Pollmacher T., Labeur M., Holsboer F., Reul J.M., et al. Glucocorticoids suppress interleukin-1 receptor antagonist synthesis following induction by endotoxin. Endocrinology 134 2 (1994) 672-677
-
(1994)
Endocrinology
, vol.134
, Issue.2
, pp. 672-677
-
-
Arzt, E.1
Sauer, J.2
Pollmacher, T.3
Labeur, M.4
Holsboer, F.5
Reul, J.M.6
-
12
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
-
Auphan N., DiDonato J.A., Rosette C., Helmberg A., and Karin M. Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis. Science 270 5234 (1995) 286-290
-
(1995)
Science
, vol.270
, Issue.5234
, pp. 286-290
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
13
-
-
2942606066
-
Structure and evolution of transcriptional regulatory networks
-
Babu M.M., Luscombe N.M., Aravind L., Gerstein M., and Teichmann S.A. Structure and evolution of transcriptional regulatory networks. Current Opinion in Structural Biology 14 3 (2004) 283-291
-
(2004)
Current Opinion in Structural Biology
, vol.14
, Issue.3
, pp. 283-291
-
-
Babu, M.M.1
Luscombe, N.M.2
Aravind, L.3
Gerstein, M.4
Teichmann, S.A.5
-
14
-
-
0742305866
-
Network biology: Understanding the cell's functional organization
-
Barabasi A.L., and Oltvai Z.N. Network biology: Understanding the cell's functional organization. Nature Review Genetics 5 2 (2004) 101-113
-
(2004)
Nature Review Genetics
, vol.5
, Issue.2
, pp. 101-113
-
-
Barabasi, A.L.1
Oltvai, Z.N.2
-
15
-
-
0027196668
-
Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man
-
Barber A.E., Coyle S.M., Marano M.A., Fischer E., Calvano S.E., Fong Y., et al. Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. Journal of Immunology 150 5 (1993) 1999-2006
-
(1993)
Journal of Immunology
, vol.150
, Issue.5
, pp. 1999-2006
-
-
Barber, A.E.1
Coyle, S.M.2
Marano, M.A.3
Fischer, E.4
Calvano, S.E.5
Fong, Y.6
-
16
-
-
33744477341
-
How corticosteroids control inflammation: Quintiles Prize Lecture 2005
-
Barnes P.J. How corticosteroids control inflammation: Quintiles Prize Lecture 2005. British Journal Pharmacology 148 3 (2006) 245-254
-
(2006)
British Journal Pharmacology
, vol.148
, Issue.3
, pp. 245-254
-
-
Barnes, P.J.1
-
17
-
-
0030615201
-
Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
-
Barnes P.J., and Karin M. Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases. New England Journal of Medicine 336 15 (1997) 1066-1071
-
(1997)
New England Journal of Medicine
, vol.336
, Issue.15
, pp. 1066-1071
-
-
Barnes, P.J.1
Karin, M.2
-
18
-
-
0035826096
-
Efficacy and safety of recombinant human activated protein C for severe sepsis
-
Bernard G.R., Vincent J.L., Laterre P.F., LaRosa S.P., Dhainaut J.F., Lopez-Rodriguez A., et al. Efficacy and safety of recombinant human activated protein C for severe sepsis. New England Journal of Medicine 344 10 (2001) 699-709
-
(2001)
New England Journal of Medicine
, vol.344
, Issue.10
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
LaRosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
-
20
-
-
0037142987
-
Association between mitochondrial dysfunction and severity and outcome of septic shock
-
Brealey D., Brand M., Hargreaves I., Heales S., Land J., Smolenski R., et al. Association between mitochondrial dysfunction and severity and outcome of septic shock. Lancet 360 9328 (2002) 219-223
-
(2002)
Lancet
, vol.360
, Issue.9328
, pp. 219-223
-
-
Brealey, D.1
Brand, M.2
Hargreaves, I.3
Heales, S.4
Land, J.5
Smolenski, R.6
-
21
-
-
0034651850
-
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages
-
Brightbill H.D., Plevy S.E., Modlin R.L., and Smale S.T. A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophages. Journal of Immunology 164 4 (2000) 1940-1951
-
(2000)
Journal of Immunology
, vol.164
, Issue.4
, pp. 1940-1951
-
-
Brightbill, H.D.1
Plevy, S.E.2
Modlin, R.L.3
Smale, S.T.4
-
22
-
-
27144509163
-
A network-based analysis of systemic inflammation in humans
-
Calvano S.E., Xiao W., Richards D.R., Felciano R.M., Baker H.V., Cho R.J., et al. A network-based analysis of systemic inflammation in humans. Nature 437 7061 (2005) 1032-1037
-
(2005)
Nature
, vol.437
, Issue.7061
, pp. 1032-1037
-
-
Calvano, S.E.1
Xiao, W.2
Richards, D.R.3
Felciano, R.M.4
Baker, H.V.5
Cho, R.J.6
-
23
-
-
34249707214
-
Nuclear factor-kappaB: Activation and regulation during toll-like receptor signaling
-
Carmody R.J., and Chen Y.H. Nuclear factor-kappaB: Activation and regulation during toll-like receptor signaling. Cellular & Molecular Immunology 4 1 (2007) 31-41
-
(2007)
Cellular & Molecular Immunology
, vol.4
, Issue.1
, pp. 31-41
-
-
Carmody, R.J.1
Chen, Y.H.2
-
25
-
-
21744440089
-
The acute inflammatory response in diverse shock states
-
Chow C.C., Clermont G., Kumar R., Lagoa C., Tawadrous Z., Gallo D., et al. The acute inflammatory response in diverse shock states. Shock 24 1 (2005) 74-84
-
(2005)
Shock
, vol.24
, Issue.1
, pp. 74-84
-
-
Chow, C.C.1
Clermont, G.2
Kumar, R.3
Lagoa, C.4
Tawadrous, Z.5
Gallo, D.6
-
26
-
-
7744225947
-
Transcriptional networks: Reverse-engineering gene regulation on a global scale
-
Chua G., Robinson M.D., Morris Q., and Hughes T.R. Transcriptional networks: Reverse-engineering gene regulation on a global scale. Current Opinion in Microbiology 7 6 (2004) 638-646
-
(2004)
Current Opinion in Microbiology
, vol.7
, Issue.6
, pp. 638-646
-
-
Chua, G.1
Robinson, M.D.2
Morris, Q.3
Hughes, T.R.4
-
27
-
-
4043056616
-
In silico design of clinical trials: A method coming of age
-
Clermont G., Bartels J., Kumar R., Constantine G., Vodovotz Y., and Chow C. In silico design of clinical trials: A method coming of age. Critical Care Medicine 32 10 (2004) 2061-2070
-
(2004)
Critical Care Medicine
, vol.32
, Issue.10
, pp. 2061-2070
-
-
Clermont, G.1
Bartels, J.2
Kumar, R.3
Constantine, G.4
Vodovotz, Y.5
Chow, C.6
-
28
-
-
20144387327
-
Application of genome-wide expression analysis to human health and disease
-
Cobb J.P., Mindrinos M.N., Miller-Graziano C., Calvano S.E., Baker H.V., Xiao W., et al. Application of genome-wide expression analysis to human health and disease. Proceedings of the National Academy of Sciences of the United States of America 102 13 (2005) 4801-4806
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.13
, pp. 4801-4806
-
-
Cobb, J.P.1
Mindrinos, M.N.2
Miller-Graziano, C.3
Calvano, S.E.4
Baker, H.V.5
Xiao, W.6
-
29
-
-
0033736476
-
Genetic network inference: From co-expression clustering to reverse engineering
-
D'Haeseleer P., Liang S., and Somogyi R. Genetic network inference: From co-expression clustering to reverse engineering. Bioinformatics 16 8 (2000) 707-726
-
(2000)
Bioinformatics
, vol.16
, Issue.8
, pp. 707-726
-
-
D'Haeseleer, P.1
Liang, S.2
Somogyi, R.3
-
30
-
-
2442687038
-
A mixed integer linear programming (MILP) framework for inferring time delay in gene regulatory networks
-
Dasika M.S., Gupta A., and Maranas C.D. A mixed integer linear programming (MILP) framework for inferring time delay in gene regulatory networks. Pacific Symposium on Biocomputing (2004) 474-485
-
(2004)
Pacific Symposium on Biocomputing
, pp. 474-485
-
-
Dasika, M.S.1
Gupta, A.2
Maranas, C.D.3
-
31
-
-
33747094446
-
A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration
-
Day J., Rubin J., Vodovotz Y., Chow C.C., Reynolds A., and Clermont G. A reduced mathematical model of the acute inflammatory response II. Capturing scenarios of repeated endotoxin administration. Journal of Theoretical Biology 242 1 (2006) 237-256
-
(2006)
Journal of Theoretical Biology
, vol.242
, Issue.1
, pp. 237-256
-
-
Day, J.1
Rubin, J.2
Vodovotz, Y.3
Chow, C.C.4
Reynolds, A.5
Clermont, G.6
-
32
-
-
0034085737
-
Metabolic management of patients with severe burns
-
Demling R.H., and Seigne P. Metabolic management of patients with severe burns. World Journal of Surgery 24 (2000) 673-680
-
(2000)
World Journal of Surgery
, vol.24
, pp. 673-680
-
-
Demling, R.H.1
Seigne, P.2
-
33
-
-
0028817007
-
Differential dynamics of receptor down-regulation and tyrosine aminotransferase induction following glucocorticoid treatment
-
DuBois D.C., Xu Z.X., McKay L., Almon R.R., Pyszcznski N., and Jusko W.J. Differential dynamics of receptor down-regulation and tyrosine aminotransferase induction following glucocorticoid treatment. The Journal of Steroid Biochemistry and Molecular Biology 54 5-6 (1995) 237-243
-
(1995)
The Journal of Steroid Biochemistry and Molecular Biology
, vol.54
, Issue.5-6
, pp. 237-243
-
-
DuBois, D.C.1
Xu, Z.X.2
McKay, L.3
Almon, R.R.4
Pyszcznski, N.5
Jusko, W.J.6
-
34
-
-
0038466078
-
Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis
-
Feterowski C., Emmanuilidis K., Miethke T., Gerauer K., Rump M., Ulm K., et al. Effects of functional Toll-like receptor-4 mutations on the immune response to human and experimental sepsis. Immunology 109 3 (2003) 426-431
-
(2003)
Immunology
, vol.109
, Issue.3
, pp. 426-431
-
-
Feterowski, C.1
Emmanuilidis, K.2
Miethke, T.3
Gerauer, K.4
Rump, M.5
Ulm, K.6
-
35
-
-
62849110685
-
An indirect response model of endotoxin-induced systemic inflammation
-
Foteinou P., Calvano S., Lowry S., and Androulakis I. An indirect response model of endotoxin-induced systemic inflammation. Journal of Critical Care 22 4 (2007) 337-338
-
(2007)
Journal of Critical Care
, vol.22
, Issue.4
, pp. 337-338
-
-
Foteinou, P.1
Calvano, S.2
Lowry, S.3
Androulakis, I.4
-
36
-
-
62849112761
-
In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation
-
Foteinou P.T., Calvano S.E., Lowry S.F., and Androulakis I.P. In silico simulation of corticosteroids effect on an NFkB-dependent physicochemical model of systemic inflammation. PLoS ONE 4 3 (2009) e4706
-
(2009)
PLoS ONE
, vol.4
, Issue.3
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
37
-
-
57849104348
-
Modeling endotoxin-induced systemic inflammation using an indirect response approach
-
Foteinou P.T., Calvano S.E., Lowry S.F., and Androulakis I.P. Modeling endotoxin-induced systemic inflammation using an indirect response approach. Mathematical Biosciences 217 1 (2009) 27-42
-
(2009)
Mathematical Biosciences
, vol.217
, Issue.1
, pp. 27-42
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
38
-
-
71749110416
-
Translational Potential of Systems-Based Models of Inflammation
-
Foteinou P.T., Calvano S.E., Lowry S.F., and Androulakis I.P. Translational Potential of Systems-Based Models of Inflammation. Clinical and Translational Science 2 1 (2009) 85-89
-
(2009)
Clinical and Translational Science
, vol.2
, Issue.1
, pp. 85-89
-
-
Foteinou, P.T.1
Calvano, S.E.2
Lowry, S.F.3
Androulakis, I.P.4
-
39
-
-
0038048325
-
Inferring genetic networks and identifying compound mode of action via expression profiling
-
Gardner T.S., di Bernardo D., Lorenz D., and Collins J.J. Inferring genetic networks and identifying compound mode of action via expression profiling. Science 301 5629 (2003) 102-105
-
(2003)
Science
, vol.301
, Issue.5629
, pp. 102-105
-
-
Gardner, T.S.1
di Bernardo, D.2
Lorenz, D.3
Collins, J.J.4
-
40
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub T.R., Slonim D.K., Tamayo P., Huard C., Gaasenbeek M., Mesirov J.P., et al. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science 286 5439 (1999) 531-537
-
(1999)
Science
, vol.286
, Issue.5439
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
-
41
-
-
0014495006
-
The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection
-
Greisman S.E., Hornick R.B., Wagner Jr. H.N., Woodward W.E., and Woodward T.E. The role of endotoxin during typhoid fever and tularemia in man. IV. The integrity of the endotoxin tolerance mechanisms during infection. European Journal of Clinical Investigation 48 4 (1969) 613-629
-
(1969)
European Journal of Clinical Investigation
, vol.48
, Issue.4
, pp. 613-629
-
-
Greisman, S.E.1
Hornick, R.B.2
Wagner Jr., H.N.3
Woodward, W.E.4
Woodward, T.E.5
-
42
-
-
17444430052
-
Dynamic network reconstruction from gene expression data applied to immune response during bacterial infection
-
Guthke R., Moller U., Hoffmann M., Thies F., and Topfer S. Dynamic network reconstruction from gene expression data applied to immune response during bacterial infection. Bioinformatics 21 8 (2005) 1626-1634
-
(2005)
Bioinformatics
, vol.21
, Issue.8
, pp. 1626-1634
-
-
Guthke, R.1
Moller, U.2
Hoffmann, M.3
Thies, F.4
Topfer, S.5
-
43
-
-
0026650341
-
In vivo effects of the antiglucocorticoid RU 486 on glucocorticoid and cytokine responses to Escherichia coli endotoxin
-
Hawes A.S., Rock C.S., Keogh C.V., Lowry S.F., and Calvano S.E. In vivo effects of the antiglucocorticoid RU 486 on glucocorticoid and cytokine responses to Escherichia coli endotoxin. Infection and Immunity 60 7 (1992) 2641-2647
-
(1992)
Infection and Immunity
, vol.60
, Issue.7
, pp. 2641-2647
-
-
Hawes, A.S.1
Rock, C.S.2
Keogh, C.V.3
Lowry, S.F.4
Calvano, S.E.5
-
44
-
-
34447336982
-
Perfect sampling of the master equation for gene regulatory networks
-
Hemberg M., and Barahona M. Perfect sampling of the master equation for gene regulatory networks. Biophysics Journal 93 2 (2007) 401-410
-
(2007)
Biophysics Journal
, vol.93
, Issue.2
, pp. 401-410
-
-
Hemberg, M.1
Barahona, M.2
-
45
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation
-
Hoffmann A., Levchenko A., Scott M.L., and Baltimore D. The IkappaB-NF-kappaB signaling module: Temporal control and selective gene activation. Science 298 5596 (2002) 1241-1245
-
(2002)
Science
, vol.298
, Issue.5596
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
-
46
-
-
18144408736
-
Cell fates as high-dimensional attractor states of a complex gene regulatory network
-
Huang S., Eichler G., Bar-Yam Y., and Ingber D.E. Cell fates as high-dimensional attractor states of a complex gene regulatory network. Physical Review Letters 94 12 (2005) 128701
-
(2005)
Physical Review Letters
, vol.94
, Issue.12
, pp. 128701
-
-
Huang, S.1
Eichler, G.2
Bar-Yam, Y.3
Ingber, D.E.4
-
47
-
-
17644427530
-
Sensitivity analysis of parameters controlling oscillatory signalling in the NF-kappaB pathway: The roles of IKK and IkappaBalpha
-
Ihekwaba A.E., Broomhead D.S., Grimley R.L., Benson N., and Kell D.B. Sensitivity analysis of parameters controlling oscillatory signalling in the NF-kappaB pathway: The roles of IKK and IkappaBalpha. Systems Biology (Stevenage) 1 1 (2004) 93-103
-
(2004)
Systems Biology (Stevenage)
, vol.1
, Issue.1
, pp. 93-103
-
-
Ihekwaba, A.E.1
Broomhead, D.S.2
Grimley, R.L.3
Benson, N.4
Kell, D.B.5
-
48
-
-
0141742369
-
Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays
-
Jin J.Y., Almon R.R., DuBois D.C., and Jusko W.J. Modeling of corticosteroid pharmacogenomics in rat liver using gene microarrays. The Journal of Pharmacology and Experimental Therapeutics 307 1 (2003) 93-109
-
(2003)
The Journal of Pharmacology and Experimental Therapeutics
, vol.307
, Issue.1
, pp. 93-109
-
-
Jin, J.Y.1
Almon, R.R.2
DuBois, D.C.3
Jusko, W.J.4
-
49
-
-
0028190238
-
Receptor-mediated pharmacodynamics of corticosteroids
-
Jusko W.J. Receptor-mediated pharmacodynamics of corticosteroids. Progress in Clinical and Biological Research 387 (1994) 261-270
-
(1994)
Progress in Clinical and Biological Research
, vol.387
, pp. 261-270
-
-
Jusko, W.J.1
-
50
-
-
71749120822
-
Sixth-generation model for corticosteroid pharmacodynamics: Multi-hormonal regulation of tyrosine aminotransferase in rat liver
-
Jusko W.J., DuBois D., and Almon R. Sixth-generation model for corticosteroid pharmacodynamics: Multi-hormonal regulation of tyrosine aminotransferase in rat liver. J Pharmacokinetics and Pharmacodynamics (2005)
-
(2005)
J Pharmacokinetics and Pharmacodynamics
-
-
Jusko, W.J.1
DuBois, D.2
Almon, R.3
-
51
-
-
0141987918
-
Induction of an interferon-gamma Stat3 response in nerve cells by pre-treatment with gp130 cytokines
-
Kaur N., Kim I.J., Higgins D., and Halvorsen S.W. Induction of an interferon-gamma Stat3 response in nerve cells by pre-treatment with gp130 cytokines. Journal of Neurochemistry 87 2 (2003) 437-447
-
(2003)
Journal of Neurochemistry
, vol.87
, Issue.2
, pp. 437-447
-
-
Kaur, N.1
Kim, I.J.2
Higgins, D.3
Halvorsen, S.W.4
-
52
-
-
0037441670
-
Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: A double-blind, randomized, placebo-controlled, crossover study
-
Keh D., Boehnke T., Weber-Cartens S., Schulz C., Ahlers O., Bercker S., et al. Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: A double-blind, randomized, placebo-controlled, crossover study. American Journal of Respiratory and Critical Care Medicine 167 4 (2003) 512-520
-
(2003)
American Journal of Respiratory and Critical Care Medicine
, vol.167
, Issue.4
, pp. 512-520
-
-
Keh, D.1
Boehnke, T.2
Weber-Cartens, S.3
Schulz, C.4
Ahlers, O.5
Bercker, S.6
-
53
-
-
34948866150
-
Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C
-
Kerschen E.J., Fernandez J.A., Cooley B.C., Yang X.V., Sood R., Mosnier L.O., et al. Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C. Journal of Experimental Medicine 204 10 (2007) 2439-2448
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.10
, pp. 2439-2448
-
-
Kerschen, E.J.1
Fernandez, J.A.2
Cooley, B.C.3
Yang, X.V.4
Sood, R.5
Mosnier, L.O.6
-
54
-
-
33845761551
-
A high-throughput microfluidic real-time gene expression living cell array
-
King K.R., Wang S., Irimia D., Jayaraman A., Toner M., and Yarmush M.L. A high-throughput microfluidic real-time gene expression living cell array. Lab on a Chip 7 1 (2007) 77-85
-
(2007)
Lab on a Chip
, vol.7
, Issue.1
, pp. 77-85
-
-
King, K.R.1
Wang, S.2
Irimia, D.3
Jayaraman, A.4
Toner, M.5
Yarmush, M.L.6
-
55
-
-
26444479778
-
Optimization by simulated annealing
-
Kirkpatrick S., Gelatt Jr. C.D., and Vecchi M.P. Optimization by simulated annealing. Science 220 4598 (1983) 671-680
-
(1983)
Science
, vol.220
, Issue.4598
, pp. 671-680
-
-
Kirkpatrick, S.1
Gelatt Jr., C.D.2
Vecchi, M.P.3
-
56
-
-
0037079054
-
Computational systems biology
-
Kitano H. Computational systems biology. Nature 420 6912 (2002) 206-210
-
(2002)
Nature
, vol.420
, Issue.6912
, pp. 206-210
-
-
Kitano, H.1
-
57
-
-
0036500993
-
Systems biology: A brief overview
-
Kitano H. Systems biology: A brief overview. Science 295 5560 (2002) 1662-1664
-
(2002)
Science
, vol.295
, Issue.5560
, pp. 1662-1664
-
-
Kitano, H.1
-
58
-
-
0037275649
-
Corticosteroids in sepsis: A new concept for an old drug
-
Klaitman V., and Almog Y. Corticosteroids in sepsis: A new concept for an old drug. The Israel Medical Association Journal 5 1 (2003) 51-55
-
(2003)
The Israel Medical Association Journal
, vol.5
, Issue.1
, pp. 51-55
-
-
Klaitman, V.1
Almog, Y.2
-
59
-
-
0037399130
-
Spectral biclustering of microarray data: Coclustering genes and conditions
-
Kluger Y., Basri R., Chang J.T., and Gerstein M. Spectral biclustering of microarray data: Coclustering genes and conditions. Genome Research 13 4 (2003) 703-716
-
(2003)
Genome Research
, vol.13
, Issue.4
, pp. 703-716
-
-
Kluger, Y.1
Basri, R.2
Chang, J.T.3
Gerstein, M.4
-
61
-
-
0030662187
-
Mathematical formalism for the properties of four basic models of indirect pharmacodynamic responses
-
Krzyzanski W., and Jusko W.J. Mathematical formalism for the properties of four basic models of indirect pharmacodynamic responses. Journal of Pharmacokinetics Biopharmacology 25 1 (1997) 107-123
-
(1997)
Journal of Pharmacokinetics Biopharmacology
, vol.25
, Issue.1
, pp. 107-123
-
-
Krzyzanski, W.1
Jusko, W.J.2
-
62
-
-
4043154901
-
The dynamics of acute inflammation
-
Kumar R., Clermont G., Vodovotz Y., and Chow C.C. The dynamics of acute inflammation. Journal of Theoretical Biology 230 2 (2004) 145-155
-
(2004)
Journal of Theoretical Biology
, vol.230
, Issue.2
, pp. 145-155
-
-
Kumar, R.1
Clermont, G.2
Vodovotz, Y.3
Chow, C.C.4
-
63
-
-
33751222859
-
The role of initial trauma in the host's response to injury and hemorrhage: Insights from a correlation of mathematical simulations and hepatic transcriptomic analysis
-
Lagoa C.E., Bartels J., Baratt A., Tseng G., Clermont G., Fink M.P., et al. The role of initial trauma in the host's response to injury and hemorrhage: Insights from a correlation of mathematical simulations and hepatic transcriptomic analysis. Shock 26 6 (2006) 592-600
-
(2006)
Shock
, vol.26
, Issue.6
, pp. 592-600
-
-
Lagoa, C.E.1
Bartels, J.2
Baratt, A.3
Tseng, G.4
Clermont, G.5
Fink, M.P.6
-
64
-
-
0034161560
-
On the use of the Kolmogorov-Smirnov statistical test for immunofluorescence histogram comparison
-
Lampariello F. On the use of the Kolmogorov-Smirnov statistical test for immunofluorescence histogram comparison. Cytometry 39 3 (2000) 179-188
-
(2000)
Cytometry
, vol.39
, Issue.3
, pp. 179-188
-
-
Lampariello, F.1
-
65
-
-
14044278401
-
Mechanisms of inflammation: The good, the bad and the ugly
-
Laroux F.S. Mechanisms of inflammation: The good, the bad and the ugly. Frontiers in Bioscience 9 (2004) 3156-3162
-
(2004)
Frontiers in Bioscience
, vol.9
, pp. 3156-3162
-
-
Laroux, F.S.1
-
66
-
-
0023175468
-
Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and d-galactosamine-treated mice
-
Lehmann V., Freudenberg M.A., and Galanos C. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and d-galactosamine-treated mice. Journal of Experimental Medicine 165 3 (1987) 657-663
-
(1987)
Journal of Experimental Medicine
, vol.165
, Issue.3
, pp. 657-663
-
-
Lehmann, V.1
Freudenberg, M.A.2
Galanos, C.3
-
67
-
-
17044368752
-
Gene regulatory networks for development
-
Levine M., and Davidson E.H. Gene regulatory networks for development. PNAS 102 14 (2005) 4936-4942
-
(2005)
PNAS
, vol.102
, Issue.14
, pp. 4936-4942
-
-
Levine, M.1
Davidson, E.H.2
-
68
-
-
0031616241
-
Reveal, a general reverse engineering algorithm for inference of genetic network architectures
-
Liang S., Fuhrman S., and Somogyi R. Reveal, a general reverse engineering algorithm for inference of genetic network architectures. Pacific Symposium on Biocomputing (1998) 18-29
-
(1998)
Pacific Symposium on Biocomputing
, pp. 18-29
-
-
Liang, S.1
Fuhrman, S.2
Somogyi, R.3
-
69
-
-
37849046535
-
Challenges for modeling and interpreting the complex biology of severe injury and inflammation
-
Lowry S.F., and Calvano S.E. Challenges for modeling and interpreting the complex biology of severe injury and inflammation. Journal of Leukocyte Biology 83 3 (2008) 553-557
-
(2008)
Journal of Leukocyte Biology
, vol.83
, Issue.3
, pp. 553-557
-
-
Lowry, S.F.1
Calvano, S.E.2
-
71
-
-
0038482456
-
Such stuff as dreams are made on: Mediator-directed therapy in sepsis
-
Marshall J.C. Such stuff as dreams are made on: Mediator-directed therapy in sepsis. Nature Reviews Drug Discovery 2 5 (2003) 391-405
-
(2003)
Nature Reviews Drug Discovery
, vol.2
, Issue.5
, pp. 391-405
-
-
Marshall, J.C.1
-
72
-
-
18844454313
-
Modeling MODS: What can be learned from animal models of the multiple-organ dysfunction syndrome?
-
Marshall J.C. Modeling MODS: What can be learned from animal models of the multiple-organ dysfunction syndrome?. Intensive Care Medicine 31 5 (2005) 605-608
-
(2005)
Intensive Care Medicine
, vol.31
, Issue.5
, pp. 605-608
-
-
Marshall, J.C.1
-
73
-
-
33644640503
-
Preclinical models of shock and sepsis: What can they tell us?
-
Marshall J.C., Deitch E., Moldawer L.L., Opal S., Redl H., and van der Poll T. Preclinical models of shock and sepsis: What can they tell us?. Shock 24 Suppl. 1 (2005) 1-6
-
(2005)
Shock
, vol.24
, Issue.SUPPL. 1
, pp. 1-6
-
-
Marshall, J.C.1
Deitch, E.2
Moldawer, L.L.3
Opal, S.4
Redl, H.5
van der Poll, T.6
-
74
-
-
0037208166
-
TRANSFAC: Transcriptional regulation, from patterns to profiles
-
Matys V., Fricke E., Geffers R., Gossling E., Haubrock M., Hehl R., et al. TRANSFAC: Transcriptional regulation, from patterns to profiles. Nucleic Acids Research 31 1 (2003) 374-378
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.1
, pp. 374-378
-
-
Matys, V.1
Fricke, E.2
Geffers, R.3
Gossling, E.4
Haubrock, M.5
Hehl, R.6
-
75
-
-
85047689521
-
Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation
-
McLoughlin R.M., Witowski J., Robson R.L., Wilkinson T.S., Hurst S.M., Williams A.S., et al. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. The Journal of Clinical Investigation 112 4 (2003) 598-607
-
(2003)
The Journal of Clinical Investigation
, vol.112
, Issue.4
, pp. 598-607
-
-
McLoughlin, R.M.1
Witowski, J.2
Robson, R.L.3
Wilkinson, T.S.4
Hurst, S.M.5
Williams, A.S.6
-
76
-
-
0032496894
-
Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: A randomized controlled trial
-
Meduri G.U., Headley A.S., Golden E., Carson S.J., Umberger R.A., Kelso T., et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: A randomized controlled trial. JAMA 280 2 (1998) 159-165
-
(1998)
JAMA
, vol.280
, Issue.2
, pp. 159-165
-
-
Meduri, G.U.1
Headley, A.S.2
Golden, E.3
Carson, S.J.4
Umberger, R.A.5
Kelso, T.6
-
77
-
-
0011116268
-
Systems theory and biology-view of a theoretician
-
Mesarovic M.D. (Ed), Springer-Verlag, New York
-
Mesarovic M.D. Systems theory and biology-view of a theoretician. In: Mesarovic M.D. (Ed). Systems theory and biology (1968), Springer-Verlag, New York 59-87
-
(1968)
Systems theory and biology
, pp. 59-87
-
-
Mesarovic, M.D.1
-
78
-
-
0031011323
-
The decrease in nonsplenic interleukin-6 (IL-6) production after splenectomy indicates the existence of a positive feedback loop of IL-6 production during endotoxemia in dogs
-
Moeniralam H.S., Bemelman W.A., Endert E., Koopmans R., Sauerwein H.P., and Romijn J.A. The decrease in nonsplenic interleukin-6 (IL-6) production after splenectomy indicates the existence of a positive feedback loop of IL-6 production during endotoxemia in dogs. Infection and Immunity 65 6 (1997) 2299-2305
-
(1997)
Infection and Immunity
, vol.65
, Issue.6
, pp. 2299-2305
-
-
Moeniralam, H.S.1
Bemelman, W.A.2
Endert, E.3
Koopmans, R.4
Sauerwein, H.P.5
Romijn, J.A.6
-
79
-
-
33847351136
-
The JAK-STAT signaling pathway: Input and output integration
-
Murray P.J. The JAK-STAT signaling pathway: Input and output integration. Journal of Immunology 178 5 (2007) 2623-2629
-
(2007)
Journal of Immunology
, vol.178
, Issue.5
, pp. 2623-2629
-
-
Murray, P.J.1
-
80
-
-
0037174638
-
Systems biology. Life's complexity pyramid
-
Oltvai Z.N., and Barabasi A.L. Systems biology. Life's complexity pyramid. Science 298 5594 (2002) 763-764
-
(2002)
Science
, vol.298
, Issue.5594
, pp. 763-764
-
-
Oltvai, Z.N.1
Barabasi, A.L.2
-
81
-
-
33646137384
-
A systematic comparison and evaluation of biclustering methods for gene expression data
-
Prelic A., Bleuler S., Zimmermann P., Wille A., Buhlmann P., Gruissem W., et al. A systematic comparison and evaluation of biclustering methods for gene expression data. Bioinformatics 22 9 (2006) 1122-1129
-
(2006)
Bioinformatics
, vol.22
, Issue.9
, pp. 1122-1129
-
-
Prelic, A.1
Bleuler, S.2
Zimmermann, P.3
Wille, A.4
Buhlmann, P.5
Gruissem, W.6
-
82
-
-
34247127759
-
Strategies to modulate cellular energetic metabolism during sepsis
-
(discussion 16-20, 160-4)
-
Protti A., and Singer M. Strategies to modulate cellular energetic metabolism during sepsis. Novartis Foundation Symposium 280 (2007) 7-16 (discussion 16-20, 160-4)
-
(2007)
Novartis Foundation Symposium
, vol.280
, pp. 7-16
-
-
Protti, A.1
Singer, M.2
-
83
-
-
0027319435
-
Modulation of glucocorticosteroid binding in human lymphoid, monocytoid and hepatoma cell lines by inflammatory cytokines interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha
-
Rakasz E., Gal A., Biro J., Balas G., and Falus A. Modulation of glucocorticosteroid binding in human lymphoid, monocytoid and hepatoma cell lines by inflammatory cytokines interleukin (IL)-1 beta, IL-6 and tumour necrosis factor (TNF)-alpha. Scandinavian Journal of Immunology 37 6 (1993) 684-689
-
(1993)
Scandinavian Journal of Immunology
, vol.37
, Issue.6
, pp. 684-689
-
-
Rakasz, E.1
Gal, A.2
Biro, J.3
Balas, G.4
Falus, A.5
-
84
-
-
0036021823
-
Fifth-generation model for corticosteroid pharmacodynamics: Application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats
-
Ramakrishnan R., DuBois D.C., Almon R.R., Pyszczynski N.A., and Jusko W.J. Fifth-generation model for corticosteroid pharmacodynamics: Application to steady-state receptor down-regulation and enzyme induction patterns during seven-day continuous infusion of methylprednisolone in rats. Journal of Pharmacokinetics and Pharmacodynamics 29 1 (2002) 1-24
-
(2002)
Journal of Pharmacokinetics and Pharmacodynamics
, vol.29
, Issue.1
, pp. 1-24
-
-
Ramakrishnan, R.1
DuBois, D.C.2
Almon, R.R.3
Pyszczynski, N.A.4
Jusko, W.J.5
-
85
-
-
0030636279
-
The release of tumor necrosis factor alpha (TNF-alpha) by interferon gamma (IFN-gamma) induced THP-1 cells stimulated with smooth lipopolysaccharide is inhibited by MAbs against HLA-DR and CD14 receptors on the effector cell
-
Raponi G., Ghezzi M.C., and Mancini C. The release of tumor necrosis factor alpha (TNF-alpha) by interferon gamma (IFN-gamma) induced THP-1 cells stimulated with smooth lipopolysaccharide is inhibited by MAbs against HLA-DR and CD14 receptors on the effector cell. New Microbiology 20 1 (1997) 1-6
-
(1997)
New Microbiology
, vol.20
, Issue.1
, pp. 1-6
-
-
Raponi, G.1
Ghezzi, M.C.2
Mancini, C.3
-
86
-
-
33747106908
-
A reduced mathematical model of the acute inflammatory response. I. Derivation of model and analysis of anti-inflammation
-
Reynolds A., Rubin J., Clermont G., Day J., Vodovotz Y., and Bard Ermentrout G. A reduced mathematical model of the acute inflammatory response. I. Derivation of model and analysis of anti-inflammation. Journal of Theoretical Biology 242 1 (2006) 220-236
-
(2006)
Journal of Theoretical Biology
, vol.242
, Issue.1
, pp. 220-236
-
-
Reynolds, A.1
Rubin, J.2
Clermont, G.3
Day, J.4
Vodovotz, Y.5
Bard Ermentrout, G.6
-
87
-
-
0000419899
-
Smoothing splines: Regression, derivatives and deconvolution
-
Rice J., and Rosenblatt M. Smoothing splines: Regression, derivatives and deconvolution. The Annals of Statistics 11 1 (1983) 141-156
-
(1983)
The Annals of Statistics
, vol.11
, Issue.1
, pp. 141-156
-
-
Rice, J.1
Rosenblatt, M.2
-
88
-
-
0024340149
-
Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human subjects. Influence of elicited hormones and cytokines
-
Richardson R.P., Rhyne C.D., Fong Y., Hesse D.G., Tracey K.J., Marano M.A., et al. Peripheral blood leukocyte kinetics following in vivo lipopolysaccharide (LPS) administration to normal human subjects. Influence of elicited hormones and cytokines. Annals of Surgery 210 2 (1989) 239-245
-
(1989)
Annals of Surgery
, vol.210
, Issue.2
, pp. 239-245
-
-
Richardson, R.P.1
Rhyne, C.D.2
Fong, Y.3
Hesse, D.G.4
Tracey, K.J.5
Marano, M.A.6
-
89
-
-
0038578608
-
Novel strategies for the treatment of sepsis
-
Riedemann N.C., Guo R.F., and Ward P.A. Novel strategies for the treatment of sepsis. Nature Medicine 9 5 (2003) 517-524
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 517-524
-
-
Riedemann, N.C.1
Guo, R.F.2
Ward, P.A.3
-
90
-
-
0014077554
-
Prevention by polymyxin B of endotoxin lethality in mice
-
Rifkind D. Prevention by polymyxin B of endotoxin lethality in mice. Journal of Bacteriology 93 4 (1967) 1463-1464
-
(1967)
Journal of Bacteriology
, vol.93
, Issue.4
, pp. 1463-1464
-
-
Rifkind, D.1
-
91
-
-
7444261000
-
Interferon-gamma acts proapoptotic on hepatic stellate cells (HSC) and abrogates the antiapoptotic effect of interferon-alpha by an HSP70-dependant pathway
-
Saile B., Eisenbach C., Dudas J., El-Armouche H., and Ramadori G. Interferon-gamma acts proapoptotic on hepatic stellate cells (HSC) and abrogates the antiapoptotic effect of interferon-alpha by an HSP70-dependant pathway. European Journal of Cell Biology 83 9 (2004) 469-476
-
(2004)
European Journal of Cell Biology
, vol.83
, Issue.9
, pp. 469-476
-
-
Saile, B.1
Eisenbach, C.2
Dudas, J.3
El-Armouche, H.4
Ramadori, G.5
-
93
-
-
0026674661
-
Tumor necrosis factor-alpha and IL-6 up-regulate IFN-gamma receptor gene expression in human monocytic THP-1 cells by transcriptional and post-transcriptional mechanisms
-
Sanceau J., Merlin G., and Wietzerbin J. Tumor necrosis factor-alpha and IL-6 up-regulate IFN-gamma receptor gene expression in human monocytic THP-1 cells by transcriptional and post-transcriptional mechanisms. Journal of Immunology 149 5 (1992) 1671-1675
-
(1992)
Journal of Immunology
, vol.149
, Issue.5
, pp. 1671-1675
-
-
Sanceau, J.1
Merlin, G.2
Wietzerbin, J.3
-
94
-
-
0036320338
-
Randomized study of the benefits of preoperative corticosteroid administration on the postoperative morbidity and cytokine response in patients undergoing surgery for esophageal cancer
-
Sato N., Koeda K., Ikeda K., Kimura Y., Aoki K., Iwaya T., et al. Randomized study of the benefits of preoperative corticosteroid administration on the postoperative morbidity and cytokine response in patients undergoing surgery for esophageal cancer. Annals of Surgery 236 2 (2002) 184-190
-
(2002)
Annals of Surgery
, vol.236
, Issue.2
, pp. 184-190
-
-
Sato, N.1
Koeda, K.2
Ikeda, K.3
Kimura, Y.4
Aoki, K.5
Iwaya, T.6
-
95
-
-
0033866133
-
Multiple organ dysfunction syndrome: Exploring the paradigm of complex nonlinear systems
-
Seely A.J., and Christou N.V. Multiple organ dysfunction syndrome: Exploring the paradigm of complex nonlinear systems. Critical Care Medicine 28 7 (2000) 2193-2200
-
(2000)
Critical Care Medicine
, vol.28
, Issue.7
, pp. 2193-2200
-
-
Seely, A.J.1
Christou, N.V.2
-
96
-
-
35048817885
-
Kinetics of binding of LPS to recombinant CD14, TLR4, and MD-2 proteins
-
Shin H.J., Lee H., Park J.D., Hyun H.C., Sohn H.O., Lee D.W., et al. Kinetics of binding of LPS to recombinant CD14, TLR4, and MD-2 proteins. Molecules and Cells 24 1 (2007) 119-124
-
(2007)
Molecules and Cells
, vol.24
, Issue.1
, pp. 119-124
-
-
Shin, H.J.1
Lee, H.2
Park, J.D.3
Hyun, H.C.4
Sohn, H.O.5
Lee, D.W.6
-
97
-
-
4043128084
-
Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation
-
Singer M., De Santis V., Vitale D., and Jeffcoate W. Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation. Lancet 364 9433 (2004) 545-548
-
(2004)
Lancet
, vol.364
, Issue.9433
, pp. 545-548
-
-
Singer, M.1
De Santis, V.2
Vitale, D.3
Jeffcoate, W.4
-
98
-
-
0032456263
-
Fourth-generation model for corticosteroid pharmacodynamics: A model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver
-
Sun Y.N., DuBois D.C., Almon R.R., and Jusko W.J. Fourth-generation model for corticosteroid pharmacodynamics: A model for methylprednisolone effects on receptor/gene-mediated glucocorticoid receptor down-regulation and tyrosine aminotransferase induction in rat liver. Journal of Pharmacokinetics and Biopharmacology 26 3 (1998) 289-317
-
(1998)
Journal of Pharmacokinetics and Biopharmacology
, vol.26
, Issue.3
, pp. 289-317
-
-
Sun, Y.N.1
DuBois, D.C.2
Almon, R.R.3
Jusko, W.J.4
-
99
-
-
0031743573
-
Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: Synergistic activation of IL-6 response element by IL-6 and glucocorticoid
-
Takeda T., Kurachi H., Yamamoto T., Nishio Y., Nakatsuji Y., Morishige K., et al. Crosstalk between the interleukin-6 (IL-6)-JAK-STAT and the glucocorticoid-nuclear receptor pathway: Synergistic activation of IL-6 response element by IL-6 and glucocorticoid. Journal of Endocrinology 159 2 (1998) 323-330
-
(1998)
Journal of Endocrinology
, vol.159
, Issue.2
, pp. 323-330
-
-
Takeda, T.1
Kurachi, H.2
Yamamoto, T.3
Nishio, Y.4
Nakatsuji, Y.5
Morishige, K.6
-
100
-
-
34247845346
-
Recent insights into the pathogenesis of severe sepsis
-
Tetta C., Fonsato V., Ronco C., and Camussi G. Recent insights into the pathogenesis of severe sepsis. Critical Care Resuscitation 7 1 (2005) 32-39
-
(2005)
Critical Care Resuscitation
, vol.7
, Issue.1
, pp. 32-39
-
-
Tetta, C.1
Fonsato, V.2
Ronco, C.3
Camussi, G.4
-
101
-
-
3242664287
-
Dynamic gene expression profiling using a microfabricated living cell array
-
Thompson D.M., King K.R., Wieder K.J., Toner M., Yarmush M.L., and Jayaraman A. Dynamic gene expression profiling using a microfabricated living cell array. Analytical Chemistry 76 14 (2004) 4098-4103
-
(2004)
Analytical Chemistry
, vol.76
, Issue.14
, pp. 4098-4103
-
-
Thompson, D.M.1
King, K.R.2
Wieder, K.J.3
Toner, M.4
Yarmush, M.L.5
Jayaraman, A.6
-
102
-
-
14844286390
-
Reverse-engineering transcription control networks
-
Timothy S., and Gardner J.J.F. Reverse-engineering transcription control networks. Physics of Life Reviews 2 (2005) 65-88
-
(2005)
Physics of Life Reviews
, vol.2
, pp. 65-88
-
-
Timothy, S.1
Gardner, J.J.F.2
-
104
-
-
0037376655
-
Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell
-
Tyson J.J., Chen K.C., and Novak B. Sniffers, buzzers, toggles and blinkers: Dynamics of regulatory and signaling pathways in the cell. Current Opinion in Cell Biology 15 2 (2003) 221-231
-
(2003)
Current Opinion in Cell Biology
, vol.15
, Issue.2
, pp. 221-231
-
-
Tyson, J.J.1
Chen, K.C.2
Novak, B.3
-
106
-
-
11144248635
-
The topological relationship between the large-scale attributes and local interaction patterns of complex networks
-
Vazquez A., Dobrin R., Sergi D., Eckmann J.P., Oltvai Z.N., and Barabasi A.L. The topological relationship between the large-scale attributes and local interaction patterns of complex networks. Proceedings of the National Academy of Sciences of the United States of America 101 52 (2004) 17940-17945
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.52
, pp. 17940-17945
-
-
Vazquez, A.1
Dobrin, R.2
Sergi, D.3
Eckmann, J.P.4
Oltvai, Z.N.5
Barabasi, A.L.6
-
107
-
-
4844229870
-
Expression profiling analysis of the metabolic and inflammatory changes following burn injury in rats
-
Vemula M., Berthiaume F., Jayaraman A., and Yarmush M.L. Expression profiling analysis of the metabolic and inflammatory changes following burn injury in rats. Physiological Genomics 18 1 (2004) 87-98
-
(2004)
Physiological Genomics
, vol.18
, Issue.1
, pp. 87-98
-
-
Vemula, M.1
Berthiaume, F.2
Jayaraman, A.3
Yarmush, M.L.4
-
108
-
-
33747341838
-
In silico models of acute inflammation in animals
-
Vodovotz Y., Chow C.C., Bartels J., Lagoa C., Prince J.M., Levy R.M., et al. In silico models of acute inflammation in animals. Shock 26 3 (2006) 235-244
-
(2006)
Shock
, vol.26
, Issue.3
, pp. 235-244
-
-
Vodovotz, Y.1
Chow, C.C.2
Bartels, J.3
Lagoa, C.4
Prince, J.M.5
Levy, R.M.6
-
109
-
-
33947193958
-
Evidence-based modeling of critical illness: An initial consensus from the Society for Complexity in Acute Illness
-
Vodovotz Y., Clermont G., Hunt C.A., Lefering R., Bartels J., Seydel R., et al. Evidence-based modeling of critical illness: An initial consensus from the Society for Complexity in Acute Illness. Journal of Critical Care 22 1 (2007) 77-84
-
(2007)
Journal of Critical Care
, vol.22
, Issue.1
, pp. 77-84
-
-
Vodovotz, Y.1
Clermont, G.2
Hunt, C.A.3
Lefering, R.4
Bartels, J.5
Seydel, R.6
-
110
-
-
57749172576
-
Mechanistic simulations of inflammation: Current state and future prospects
-
Vodovotz Y., Constantine G., Rubin J., Csete M., Voit E.O., and An G. Mechanistic simulations of inflammation: Current state and future prospects. Mathematical Biosciences 217 1 (2009) 1-10
-
(2009)
Mathematical Biosciences
, vol.217
, Issue.1
, pp. 1-10
-
-
Vodovotz, Y.1
Constantine, G.2
Rubin, J.3
Csete, M.4
Voit, E.O.5
An, G.6
-
111
-
-
43249089766
-
Translational systems biology of inflammation
-
Vodovotz Y., Csete M., Bartels J., Chang S., and An G. Translational systems biology of inflammation. PLoS Computational Biology 4 4 (2008) e1000014
-
(2008)
PLoS Computational Biology
, vol.4
, Issue.4
-
-
Vodovotz, Y.1
Csete, M.2
Bartels, J.3
Chang, S.4
An, G.5
-
112
-
-
24144491073
-
Optimization of reporter cells for expression profiling in a microfluidic device
-
Wieder K.J., King K.R., Thompson D.M., Zia C., Yarmush M.L., and Jayaraman A. Optimization of reporter cells for expression profiling in a microfluidic device. Biomedical Microdevices 7 3 (2005) 213-222
-
(2005)
Biomedical Microdevices
, vol.7
, Issue.3
, pp. 213-222
-
-
Wieder, K.J.1
King, K.R.2
Thompson, D.M.3
Zia, C.4
Yarmush, M.L.5
Jayaraman, A.6
-
113
-
-
0345359924
-
A positive-feedback-based bistable 'memory module' that governs a cell fate decision
-
Xiong W., and Ferrell Jr. J.E. A positive-feedback-based bistable 'memory module' that governs a cell fate decision. Nature 426 6965 (2003) 460-465
-
(2003)
Nature
, vol.426
, Issue.6965
, pp. 460-465
-
-
Xiong, W.1
Ferrell Jr., J.E.2
-
114
-
-
0029552810
-
Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver
-
Xu Z.X., Sun Y.N., DuBois D.C., Almon R.R., and Jusko W.J. Third-generation model for corticosteroid pharmacodynamics: Roles of glucocorticoid receptor mRNA and tyrosine aminotransferase mRNA in rat liver. Journal of Pharmacokinetics and Biopharmacology 23 2 (1995) 163-181
-
(1995)
Journal of Pharmacokinetics and Biopharmacology
, vol.23
, Issue.2
, pp. 163-181
-
-
Xu, Z.X.1
Sun, Y.N.2
DuBois, D.C.3
Almon, R.R.4
Jusko, W.J.5
-
115
-
-
34548715826
-
A novel non-overlapping bi-clustering algorithm for network generation using living cell array data
-
Yang E., Foteinou P.T., King K.R., Yarmush M.L., and Androulakis I.P. A novel non-overlapping bi-clustering algorithm for network generation using living cell array data. Bioinformatics 23 17 (2007) 2306-2313
-
(2007)
Bioinformatics
, vol.23
, Issue.17
, pp. 2306-2313
-
-
Yang, E.1
Foteinou, P.T.2
King, K.R.3
Yarmush, M.L.4
Androulakis, I.P.5
-
116
-
-
33847139783
-
Bioinformatics analysis of the early inflammatory response in a rat thermal injury model
-
Yang E., Maguire T., Yarmush M.L., Berthiaume F., and Androulakis I.P. Bioinformatics analysis of the early inflammatory response in a rat thermal injury model. BMC Bioinformatics 8 1 (2007) 10
-
(2007)
BMC Bioinformatics
, vol.8
, Issue.1
, pp. 10
-
-
Yang, E.1
Maguire, T.2
Yarmush, M.L.3
Berthiaume, F.4
Androulakis, I.P.5
-
117
-
-
58149131267
-
Transcription factor network reconstruction using the living cell array
-
Yang E., Yarmush M.L., and Androulakis I.P. Transcription factor network reconstruction using the living cell array. Journal of Theoretical Biology 256 3 (2009) 393-407
-
(2009)
Journal of Theoretical Biology
, vol.256
, Issue.3
, pp. 393-407
-
-
Yang, E.1
Yarmush, M.L.2
Androulakis, I.P.3
-
118
-
-
27544510864
-
Discovering coherent biclusters from gene expression data using zero-suppressed binary decision diagrams
-
Yoon S., Nardini C., Benini L., and De Micheli G. Discovering coherent biclusters from gene expression data using zero-suppressed binary decision diagrams. IEEE/ACM Transactions on Computational Biology and Bioinformatics 2 4 (2005) 339-354
-
(2005)
IEEE/ACM Transactions on Computational Biology and Bioinformatics
, vol.2
, Issue.4
, pp. 339-354
-
-
Yoon, S.1
Nardini, C.2
Benini, L.3
De Micheli, G.4
-
119
-
-
36949004699
-
From inverse problems in mathematical physiology to quantitative differential diagnoses
-
Zenker S., Rubin J., and Clermont G. From inverse problems in mathematical physiology to quantitative differential diagnoses. PLoS Computational Biology 3 11 (2007) e204
-
(2007)
PLoS Computational Biology
, vol.3
, Issue.11
-
-
Zenker, S.1
Rubin, J.2
Clermont, G.3
-
120
-
-
34247623628
-
Getting connected: Analysis and principles of biological networks
-
Zhu X., Gerstein M., and Snyder M. Getting connected: Analysis and principles of biological networks. Genes and Development 21 9 (2007) 1010-1024
-
(2007)
Genes and Development
, vol.21
, Issue.9
, pp. 1010-1024
-
-
Zhu, X.1
Gerstein, M.2
Snyder, M.3
-
121
-
-
0025198763
-
Modeling of the bacterial growth curve
-
Zwietering M.H., Jongenburger I., Rombouts F.M., and van 't Riet K. Modeling of the bacterial growth curve. Applied Environmental Microbiology 56 6 (1990) 1875-1881
-
(1990)
Applied Environmental Microbiology
, vol.56
, Issue.6
, pp. 1875-1881
-
-
Zwietering, M.H.1
Jongenburger, I.2
Rombouts, F.M.3
van 't Riet, K.4
|