Pharmacodynamics and pharmacogenomics of diverse receptor-mediated effects of methylprednisolone in rats using microarray analysis

Journal of Pharmacokinetics and Pharmacodynamics

Volumn 29, Issue 2, 2002, Pages 103-129

  Almon, R R ^a   DuBois, D C ^a   Brandenburg, E H ^a   Shi, W ^a   Zhang, S ^a   Straubinger, R M ^a   Jusko, W J ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Corticosteroids; Microarrays; Pharmacodynamics; Pharmacogenomics

Indexed keywords

COMPLEMENTARY DNA; CORTICOSTEROID; GLUCOCORTICOID RECEPTOR; METHYLPREDNISOLONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORTICOSTEROID BLOOD LEVEL; DNA MICROARRAY; DOSE TIME EFFECT RELATION; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENERGY METABOLISM; EXPERIMENTAL MODEL; GENE EXPRESSION; GENE REPRESSION; GENETIC ANALYSIS; GENETIC VARIABILITY; IMMUNE RESPONSE; LIVER FUNCTION; MALE; NONHUMAN; NORTHERN BLOTTING; PHARMACODYNAMICS; PHARMACOGENOMICS; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE;

ANIMALS; GENE EXPRESSION REGULATION; LIVER; MALE; METHYLPREDNISOLONE; MUSCLE, SKELETAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHARMACOGENETICS; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0036553438     PISSN: 1567567X     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1019762323576     Document Type: Article

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