-
1
-
-
44349124113
-
The genetics and immunopathogenesis of inflammatory bowel disease
-
Cho JH: The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol 2008; 8: 458-466.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 458-466
-
-
Cho, J.H.1
-
2
-
-
84930302282
-
Regional ileitis: A pathologic and clinical entity
-
Crohn G: Regional ileitis: A pathologic and clinical entity. JAMA 1932; 99: 1323-1329.
-
(1932)
JAMA
, vol.99
, pp. 1323-1329
-
-
Crohn, G.1
-
3
-
-
0033693824
-
Combined segregation and linkage analysis of inflammatory bowel disease in the IBD1 region using severity to characterise Crohn's disease and ulcerative colitis. on behalf of the GISC
-
Forabosco P, Collins A, Latiano A, Annese V, Clementi M, Andriulli A, Fortina P, Devoto M, Morton NE: Combined segregation and linkage analysis of inflammatory bowel disease in the IBD1 region using severity to characterise Crohn's disease and ulcerative colitis. On behalf of the GISC. Eur J Hum Genet 2000; 8: 846-852.
-
(2000)
Eur J Hum Genet
, vol.8
, pp. 846-852
-
-
Forabosco, P.1
Collins, A.2
Latiano, A.3
Annese, V.4
Clementi, M.5
Andriulli, A.6
Fortina, P.7
Devoto, M.8
Morton, N.E.9
-
4
-
-
0019304236
-
Studies of family history among patients with inflammatory bowel disease
-
Farmer RG, Michener WM, Mortimer EA: Studies of family history among patients with inflammatory bowel disease. Clin Gastroenterol 1980; 9: 271-277.
-
(1980)
Clin Gastroenterol
, vol.9
, pp. 271-277
-
-
Farmer, R.G.1
Michener, W.M.2
Mortimer, E.A.3
-
5
-
-
0023139280
-
Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis
-
Monsen U, Brostrom O, Nordenvall B, Sorstad J, Hellers G: Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis. Scand J Gastroenterol 1987; 22: 214-218.
-
(1987)
Scand J Gastroenterol
, vol.22
, pp. 214-218
-
-
Monsen, U.1
Brostrom, O.2
Nordenvall, B.3
Sorstad, J.4
Hellers, G.5
-
6
-
-
33745473236
-
Family and twin studies in inflammatory bowel disease
-
Halme L, Paavola-Sakki P, Turunen U, Lappalainen M, Farkkila M, Kontula K: Family and twin studies in inflammatory bowel disease. World J Gastroenterol 2006; 12: 3668-3672.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 3668-3672
-
-
Halme, L.1
Paavola-Sakki, P.2
Turunen, U.3
Lappalainen, M.4
Farkkila, M.5
Kontula, K.6
-
7
-
-
38049078742
-
Longitudinal concordance for clinical characteristics in a Swedish-Danish twin population with inflammatory bowel disease
-
Halfvarson J, Jess T, Bodin L, Jarnerot G, Munkholm P, Binder V, Tysk C: Longitudinal concordance for clinical characteristics in a Swedish-Danish twin population with inflammatory bowel disease. Inflamm Bowel Dis 2007; 13: 1536-1544.
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1536-1544
-
-
Halfvarson, J.1
Jess, T.2
Bodin, L.3
Jarnerot, G.4
Munkholm, P.5
Binder, V.6
Tysk, C.7
-
8
-
-
0034991524
-
The genetics of inflammatory bowel disease
-
Ahmad T, Satsangi J, McGovern D, Bunce M, Jewell DP: The genetics of inflammatory bowel disease. Aliment Pharmacol Ther 2001; 15: 731-748.
-
(2001)
Aliment Pharmacol Ther
, vol.15
, pp. 731-748
-
-
Ahmad, T.1
Satsangi, J.2
McGovern, D.3
Bunce, M.4
Jewell, D.P.5
-
9
-
-
0025966488
-
Familial occurrence of inflammatory bowel disease
-
Orholm M, Munkholm P, Langholz E, Nielsen OH, Sorensen TI, Binder V: Familial occurrence of inflammatory bowel disease. N Engl J Med 1991; 324: 84-88.
-
(1991)
N Engl J Med
, vol.324
, pp. 84-88
-
-
Orholm, M.1
Munkholm, P.2
Langholz, E.3
Nielsen, O.H.4
Sorensen, T.I.5
Binder, V.6
-
10
-
-
0027404560
-
Familial empirical risks for inflammatory bowel disease: Differences between Jews and non-Jews
-
Yang H, McElree C, Roth MP, Shanahan F, Targan SR, Rotter JI: Familial empirical risks for inflammatory bowel disease: Differences between Jews and non-Jews. Gut 1993; 34: 517-524.
-
(1993)
Gut
, vol.34
, pp. 517-524
-
-
Yang, H.1
McElree, C.2
Roth, M.P.3
Shanahan, F.4
Targan, S.R.5
Rotter, J.I.6
-
11
-
-
0024466075
-
Geographic origins of Jewish patients with inflammatory bowel disease
-
Roth MP, Petersen GM, McElree C, Feldman E, Rotter JI: Geographic origins of Jewish patients with inflammatory bowel disease. Gastroenterology 1989; 97: 900-904.
-
(1989)
Gastroenterology
, vol.97
, pp. 900-904
-
-
Roth, M.P.1
Petersen, G.M.2
McElree, C.3
Feldman, E.4
Rotter, J.I.5
-
14
-
-
0026650949
-
Familial aggregation of inflammatory bowel disease in northern Italy: A multicenter study. the Gruppo di Studio per le Malattie Infiammatorie Intestinali
-
(IBD Study Group)
-
Meucci G, Vecchi M, Torgano G, Arrigoni M, Prada A, Rocca F, Curzio M, Pera A, de Franchis R: Familial aggregation of inflammatory bowel disease in northern Italy: A multicenter study. The Gruppo di Studio per le Malattie Infiammatorie Intestinali (IBD Study Group). Gastroenterology 1992; 103: 514-519.
-
(1992)
Gastroenterology
, vol.103
, pp. 514-519
-
-
Meucci, G.1
Vecchi, M.2
Torgano, G.3
Arrigoni, M.4
Prada, A.5
Rocca, F.6
Curzio, M.7
Pera, A.8
De Franchis, R.9
-
15
-
-
0032198308
-
Genetic epidemiology of inflammatory bowel disease
-
Binder V: Genetic epidemiology of inflammatory bowel disease. Dig Dis 1998; 16: 351-355.
-
(1998)
Dig Dis
, vol.16
, pp. 351-355
-
-
Binder, V.1
-
16
-
-
8044241569
-
Relationship between site of disease and familial occurrence in Crohn's disease
-
Cottone M, Brignola C, Rosselli M, Oliva L, Belloli C, Cipolla C, Orlando A, De Simone G, Aiala MR, Di Mitri R, Gatto G, Buccellato A: Relationship between site of disease and familial occurrence in Crohn's disease. Dig Dis Sci 1997; 42: 129-132.
-
(1997)
Dig Dis Sci
, vol.42
, pp. 129-132
-
-
Cottone, M.1
Brignola, C.2
Rosselli, M.3
Oliva, L.4
Belloli, C.5
Cipolla, C.6
Orlando, A.7
De Simone, G.8
Aiala, M.R.9
Di Mitri, R.10
Gatto, G.11
Buccellato, A.12
-
17
-
-
0029788998
-
Clinical characteristics of Crohn's disease in 72 families
-
Colombel JF, Grandbastien B, Gower-Rousseau C, Plegat S, Evrard JP, Dupas JL, Gendre JP, Modigliani R, Belaiche J, Hostein J, Hugot JP, van Kruiningen H, Cortot A: Clinical characteristics of Crohn's disease in 72 families. Gastroenterology 1996; 111: 604-607.
-
(1996)
Gastroenterology
, vol.111
, pp. 604-607
-
-
Colombel, J.F.1
Grandbastien, B.2
Gower-Rousseau, C.3
Plegat, S.4
Evrard, J.P.5
Dupas, J.L.6
Gendre, J.P.7
Modigliani, R.8
Belaiche, J.9
Hostein, J.10
Hugot, J.P.11
Van Kruiningen, H.12
Cortot, A.13
-
18
-
-
0029810041
-
Crohn's disease: Influence of age at diagnosis on site and clinical type of disease
-
Polito JM 2nd, Childs B, Mellits ED, Tokayer AZ, Harris ML, Bayless TM: Crohn's disease: influence of age at diagnosis on site and clinical type of disease. Gastroenterology 1996; 111: 580-586.
-
(1996)
Gastroenterology
, vol.111
, pp. 580-586
-
-
Polito Ii, J.M.1
Childs, B.2
Mellits, E.D.3
Tokayer, A.Z.4
Harris, M.L.5
Bayless, T.M.6
-
19
-
-
0029927577
-
Preliminary evidence for genetic anticipation in Crohn's disease
-
Polito JM 2nd, Rees RC, Childs B, Mendeloff AI, Harris ML, Bayless TM: Preliminary evidence for genetic anticipation in Crohn's disease. Lancet 1996; 347: 798-800.
-
(1996)
Lancet
, vol.347
, pp. 798-800
-
-
Polito Ii, J.M.1
Rees, R.C.2
Childs, B.3
Mendeloff, A.I.4
Harris, M.L.5
Bayless, T.M.6
-
20
-
-
0026446099
-
A second-generation linkage map of the human genome
-
Weissenbach J, Gyapay G, Dib C, Vignal A, Morissette J, Millasseau P, Vaysseix G, Lathrop M: A second-generation linkage map of the human genome. Nature 1992; 359: 794-801.
-
(1992)
Nature
, vol.359
, pp. 794-801
-
-
Weissenbach, J.1
Gyapay, G.2
Dib, C.3
Vignal, A.4
Morissette, J.5
Millasseau, P.6
Vaysseix, G.7
Lathrop, M.8
-
21
-
-
0028877463
-
Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
-
Lander E, Kruglyak L: Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11: 241-247.
-
(1995)
Nat Genet
, vol.11
, pp. 241-247
-
-
Lander, E.1
Kruglyak, L.2
-
22
-
-
17344376439
-
Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease
-
Cho JH, Nicolae DL, Ramos R, Fields CT, Rabenau K, Corradino S, Brant SR, Espinosa R, LeBeau M, Hanauer SB, Bodzin J, Bonen DK: Linkage and linkage disequilibrium in chromosome band 1p36 in American Chaldeans with inflammatory bowel disease. Hum Mol Genet 2000; 9: 1425-1432.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1425-1432
-
-
Cho, J.H.1
Nicolae, D.L.2
Ramos, R.3
Fields, C.T.4
Rabenau, K.5
Corradino, S.6
Brant, S.R.7
Espinosa, R.8
Lebeau, M.9
Hanauer, S.B.10
Bodzin, J.11
Bonen, D.K.12
-
23
-
-
0034242878
-
Linkage of inflammatory bowel disease to human chromosome 6p
-
Cho J: Linkage of inflammatory bowel disease to human chromosome 6p. Inflamm Bowel Dis 2000; 6: 259-261.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 259-261
-
-
Cho, J.1
-
24
-
-
0033358520
-
Linkage of inflammatory bowel disease to human chromosome 6p
-
DOI 10.1086/302677
-
Hampe J, Shaw SH, Saiz R, Leysens N, Lantermann A, Mascheretti S, Lynch NJ, MacPherson AJ, Bridger S, van Deventer S, Stokkers P, Morin P, Mirza MM, Forbes A, Lennard-Jones JE, Mathew CG, Curran ME, Schreiber S: Linkage of inflammatory bowel disease to human chromosome 6p. Am J Hum Genet 1999; 65: 1647-1655. (Pubitemid 30468677)
-
(1999)
American Journal of Human Genetics
, vol.65
, Issue.6
, pp. 1647-1655
-
-
Hampe, J.1
Shaw, S.H.2
Saiz, R.3
Leysens, N.4
Lantermann, A.5
Mascheretti, S.6
Lynch, N.J.7
MacPherson, A.J.S.8
Bridger, S.9
Van Deventer, S.10
Stokkers, P.11
Morin, P.12
Mirza, M.M.13
Forbes, A.14
Lennard-Jones, J.E.15
Mathew, C.G.16
Curran, M.E.17
Schreiber, S.18
-
25
-
-
11144354272
-
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1,952 affected relative pairs
-
Van Heel DA, Fisher SA, Kirby A, Daly MJ, Rioux JD, Lewis CM: Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1,952 affected relative pairs. Hum Mol Genet 2004; 13: 763-770.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 763-770
-
-
Van Heel, D.A.1
Fisher, S.A.2
Kirby, A.3
Daly, M.J.4
Rioux, J.D.5
Lewis, C.M.6
-
26
-
-
2442429216
-
Clinical relevance of advances in genetics and pharmacogenetics of IBD
-
Ahmad T, Tamboli CP, Jewell D, Colombel JF: Clinical relevance of advances in genetics and pharmacogenetics of IBD. Gastroenterology 2004; 126: 1533-1549.
-
(2004)
Gastroenterology
, vol.126
, pp. 1533-1549
-
-
Ahmad, T.1
Tamboli, C.P.2
Jewell, D.3
Colombel, J.F.4
-
27
-
-
33644773939
-
Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus
-
Achkar JP, Dassopoulos T, Silverberg MS, Tuvlin JA, Duerr RH, Brant SR, Siminovitch K, Reddy D, Datta LW, Bayless TM, Zhang L, Barmada MM, Rioux JD, Steinhart AH, McLeod RS, Griffiths AM, Cohen Z, Yang H, Bromfield GP, Schumm P, Hanauer SB, Cho JH, Nicolae DL: Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus. Am J Gastroenterol 2006; 101: 572-580.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 572-580
-
-
Achkar, J.P.1
Dassopoulos, T.2
Silverberg, M.S.3
Tuvlin, J.A.4
Duerr, R.H.5
Brant, S.R.6
Siminovitch, K.7
Reddy, D.8
Datta, L.W.9
Bayless, T.M.10
Zhang, L.11
Barmada, M.M.12
Rioux, J.D.13
Steinhart, A.H.14
McLeod, R.S.15
Griffiths, A.M.16
Cohen, Z.17
Yang, H.18
Bromfield, G.P.19
Schumm, P.20
Hanauer, S.B.21
Cho, J.H.22
Nicolae, D.L.23
more..
-
28
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, Lesage S, Cezard JP, Belaiche J, Almer S, Tysk C, O'Morain CA, Gassull M, Binder V, Finkel Y, Cortot A, Modigliani R, Laurent-Puig P, Gower-Rousseau C, Macry J, Colombel JF, Sahbatou M, Thomas G: Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001; 411: 599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'Morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
MacRy, J.17
Colombel, J.F.18
Sahbatou, M.19
Thomas, G.20
more..
-
29
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R, Britton H, Moran T, Karaliuskas R, Duerr RH, Achkar JP, Brant SR, Bayless TM, Kirschner BS, Hanauer SB, Nunez G, Cho JH: A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001; 411: 603-606.
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nunez, G.16
Cho, J.H.17
-
30
-
-
0035897904
-
Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
-
Hampe J, Cuthbert A, Croucher PJ, Mirza MM, Mascheretti S, Fisher S, Frenzel H, King K, Hasselmeyer A, MacPherson AJ, Bridger S, van Deventer S, Forbes A, Nikolaus S, Lennard-Jones JE, Foelsch UR, Krawczak M, Lewis C, Schreiber S, Mathew CG: Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations. Lancet 2001; 357: 1925-1928.
-
(2001)
Lancet
, vol.357
, pp. 1925-1928
-
-
Hampe, J.1
Cuthbert, A.2
Croucher, P.J.3
Mirza, M.M.4
Mascheretti, S.5
Fisher, S.6
Frenzel, H.7
King, K.8
Hasselmeyer, A.9
MacPherson, A.J.10
Bridger, S.11
Van Deventer, S.12
Forbes, A.13
Nikolaus, S.14
Lennard-Jones, J.E.15
Foelsch, U.R.16
Krawczak, M.17
Lewis, C.18
Schreiber, S.19
Mathew, C.G.20
more..
-
31
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
Lesage S, Zouali H, Cezard JP, Colombel JF, Belaiche J, Almer S, Tysk C, O'Morain C, Gassull M, Binder V, Finkel Y, Modigliani R, Gower-Rousseau C, Macry J, Merlin F, Chamaillard M, Jannot AS, Thomas G, Hugot JP: CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 2002; 70: 845-857.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 845-857
-
-
Lesage, S.1
Zouali, H.2
Cezard, J.P.3
Colombel, J.F.4
Belaiche, J.5
Almer, S.6
Tysk, C.7
O'Morain, C.8
Gassull, M.9
Binder, V.10
Finkel, Y.11
Modigliani, R.12
Gower-Rousseau, C.13
MacRy, J.14
Merlin, F.15
Chamaillard, M.16
Jannot, A.S.17
Thomas, G.18
Hugot, J.P.19
-
32
-
-
0036202885
-
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
-
Cuthbert AP, Fisher SA, Mirza MM, King K, Hampe J, Croucher PJ, Mascheretti S, Sanderson J, Forbes A, Mansfield J, Schreiber S, Lewis CM, Mathew CG: The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology 2002; 122: 867-874.
-
(2002)
Gastroenterology
, vol.122
, pp. 867-874
-
-
Cuthbert, A.P.1
Fisher, S.A.2
Mirza, M.M.3
King, K.4
Hampe, J.5
Croucher, P.J.6
Mascheretti, S.7
Sanderson, J.8
Forbes, A.9
Mansfield, J.10
Schreiber, S.11
Lewis, C.M.12
Mathew, C.G.13
-
33
-
-
0037062228
-
Association of NOD2 (CARD15) genotype with clinical course of Crohn's disease: A cohort study
-
Hampe J, Grebe J, Nikolaus S, Solberg C, Croucher PJ, Mascheretti S, Jahnsen J, Moum B, Klump B, Krawczak M, Mirza MM, Foelsch UR, Vatn M, Schreiber S: Association of NOD2 (CARD15) genotype with clinical course of Crohn's disease: A cohort study. Lancet 2002; 359: 1661-1665.
-
(2002)
Lancet
, vol.359
, pp. 1661-1665
-
-
Hampe, J.1
Grebe, J.2
Nikolaus, S.3
Solberg, C.4
Croucher, P.J.5
Mascheretti, S.6
Jahnsen, J.7
Moum, B.8
Klump, B.9
Krawczak, M.10
Mirza, M.M.11
Foelsch, U.R.12
Vatn, M.13
Schreiber, S.14
-
34
-
-
18444381172
-
CARD15 genetic variation in a Quebec population: Prevalence, genotype-phenotype relationship, and haplotype structure
-
Vermeire S, Wild G, Kocher K, Cousineau J, Dufresne L, Bitton A, Langelier D, Pare P, Lapointe G, Cohen A, Daly MJ, Rioux JD: CARD15 genetic variation in a Quebec population: Prevalence, genotype-phenotype relationship, and haplotype structure. Am J Hum Genet 2002; 71: 74-83.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 74-83
-
-
Vermeire, S.1
Wild, G.2
Kocher, K.3
Cousineau, J.4
Dufresne, L.5
Bitton, A.6
Langelier, D.7
Pare, P.8
Lapointe, G.9
Cohen, A.10
Daly, M.J.11
Rioux, J.D.12
-
35
-
-
4344671141
-
NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: Evidence for genetic heterogeneity within Europe?
-
Arnott ID, Nimmo ER, Drummond HE, Fennell J, Smith BR, MacKinlay E, Morecroft J, Anderson N, Kelleher D, O'Sullivan M, McManus R, Satsangi J: NOD2/CARD15, TLR4 and CD14 mutations in Scottish and Irish Crohn's disease patients: evidence for genetic heterogeneity within Europe? Genes Immun 2004; 5: 417-425.
-
(2004)
Genes Immun
, vol.5
, pp. 417-425
-
-
Arnott, I.D.1
Nimmo, E.R.2
Drummond, H.E.3
Fennell, J.4
Smith, B.R.5
MacKinlay, E.6
Morecroft, J.7
Anderson, N.8
Kelleher, D.9
O'Sullivan, M.10
McManus, R.11
Satsangi, J.12
-
36
-
-
0037265610
-
Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations
-
Croucher PJ, Mascheretti S, Hampe J, Huse K, Frenzel H, Stoll M, Lu T, Nikolaus S, Yang SK, Krawczak M, Kim WH, Schreiber S: Haplotype structure and association to Crohn's disease of CARD15 mutations in two ethnically divergent populations. Eur J Hum Genet 2003; 11: 6-16.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 6-16
-
-
Croucher, P.J.1
Mascheretti, S.2
Hampe, J.3
Huse, K.4
Frenzel, H.5
Stoll, M.6
Lu, T.7
Nikolaus, S.8
Yang, S.K.9
Krawczak, M.10
Kim, W.H.11
Schreiber, S.12
-
37
-
-
1842666807
-
NOD2 3020insC frameshift mutation is not associated with inflammatory bowel disease in Chinese patients of Han nationality
-
Guo QS, Xia B, Jiang Y, Qu Y, Li J: NOD2 3020insC frameshift mutation is not associated with inflammatory bowel disease in Chinese patients of Han nationality. World J Gastroenterol 2004; 10: 1069-1071.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 1069-1071
-
-
Guo, Q.S.1
Xia, B.2
Jiang, Y.3
Qu, Y.4
Li, J.5
-
38
-
-
1842455329
-
Genetics of inflammatory bowel disease: Progress and prospects
-
Mathew CG, Lewis CM: Genetics of inflammatory bowel disease: Progress and prospects. Hum Mol Genet 2004; 13(Spec No 1): R161-R168.
-
(2004)
Hum Mol Genet
, vol.13
, Issue.SPEC NO 1
-
-
Mathew, C.G.1
Lewis, C.M.2
-
39
-
-
0037221395
-
Crohn's disease- associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan
-
Bonen DK, Ogura Y, Nicolae DL, Inohara N, Saab L, Tanabe T, Chen FF, Foster SJ, Duerr RH, Brant SR, Cho JH, Nunez G: Crohn's disease- associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology 2003; 124: 140-146.
-
(2003)
Gastroenterology
, vol.124
, pp. 140-146
-
-
Bonen, D.K.1
Ogura, Y.2
Nicolae, D.L.3
Inohara, N.4
Saab, L.5
Tanabe, T.6
Chen, F.F.7
Foster, S.J.8
Duerr, R.H.9
Brant, S.R.10
Cho, J.H.11
Nunez, G.12
-
40
-
-
3342986671
-
NOD2/ CARD15 mutation analysis and genotypephenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease
-
Weiss B, Shamir R, Bujanover Y, Waterman M, Hartman C, Fradkin A, Berkowitz D, Weintraub I, Eliakim R, Karban A: NOD2/ CARD15 mutation analysis and genotypephenotype correlation in Jewish pediatric patients compared with adults with Crohn's disease. J Pediatr 2004; 145: 208-212.
-
(2004)
J Pediatr
, vol.145
, pp. 208-212
-
-
Weiss, B.1
Shamir, R.2
Bujanover, Y.3
Waterman, M.4
Hartman, C.5
Fradkin, A.6
Berkowitz, D.7
Weintraub, I.8
Eliakim, R.9
Karban, A.10
-
41
-
-
0036202336
-
The molecular classification of the clinical manifestations of Crohn's disease
-
Ahmad T, Armuzzi A, Bunce M, Mulcahy- Hawes K, Marshall SE, Orchard TR, Crawshaw J, Large O, de Silva A, Cook JT, Barnardo M, Cullen S, Welsh KI, Jewell DP: The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology 2002; 122: 854-866.
-
(2002)
Gastroenterology
, vol.122
, pp. 854-866
-
-
Ahmad, T.1
Armuzzi, A.2
Bunce, M.3
Mulcahy- Hawes, K.4
Marshall, S.E.5
Orchard, T.R.6
Crawshaw, J.7
Large, O.8
De Silva, A.9
Cook, J.T.10
Barnardo, M.11
Cullen, S.12
Welsh, K.I.13
Jewell, D.P.14
-
42
-
-
0036179995
-
Plain abdominal radiographic features are not reliable markers of disease extent in active ulcerative colitis
-
Langmead L, Rampton DS: Plain abdominal radiographic features are not reliable markers of disease extent in active ulcerative colitis. Am J Gastroenterol 2002; 97: 354-359.
-
(2002)
Am J Gastroenterol
, vol.97
, pp. 354-359
-
-
Langmead, L.1
Rampton, D.S.2
-
43
-
-
10744225248
-
Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis
-
Bjarnason I, Helgason KO, Geirsson AJ, Sigthorsson G, Reynisdottir I, Gudbjartsson D, Einarsdottir AS, Sherwood R, Kristjansson K, Kjartansson O, Thjodleifsson B: Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis. Gastroenterology 2003; 125: 1598-1605.
-
(2003)
Gastroenterology
, vol.125
, pp. 1598-1605
-
-
Bjarnason, I.1
Helgason, K.O.2
Geirsson, A.J.3
Sigthorsson, G.4
Reynisdottir, I.5
Gudbjartsson, D.6
Einarsdottir, A.S.7
Sherwood, R.8
Kristjansson, K.9
Kjartansson, O.10
Thjodleifsson, B.11
-
44
-
-
0037379422
-
Early development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location number of flares, and smoking but not by NOD2/ CARD15 genotype
-
Louis E, Michel V, Hugot JP, Reenaers C, Fontaine F, Delforge M, El Yafi F, Colombel JF, Belaiche J: Early development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location, number of flares, and smoking but not by NOD2/ CARD15 genotype. Gut 2003; 52: 552-557.
-
(2003)
Gut
, vol.52
, pp. 552-557
-
-
Louis, E.1
Michel, V.2
Hugot, J.P.3
Reenaers, C.4
Fontaine, F.5
Delforge, M.6
El Yafi, F.7
Colombel, J.F.8
Belaiche, J.9
-
45
-
-
0035895992
-
NOD2, a NOD1/ APAF-1 family member that is restricted to monocytes and activates NF-- B
-
Ogura Y, Inohara N, Benito A, Chen FF, Yamaoka S, Nunez G: NOD2, a NOD1/ APAF-1 family member that is restricted to monocytes and activates NF--B. J Biol Chem 2001; 276: 4812-4818.
-
(2001)
J Biol Chem
, vol.276
, pp. 4812-4818
-
-
Ogura, Y.1
Inohara, N.2
Benito, A.3
Chen, F.F.4
Yamaoka, S.5
Nunez, G.6
-
46
-
-
0038109983
-
Crohn's disease and the NOD2 gene: A role for paneth cells
-
DOI 10.1016/S0016-5085(03)00661-9
-
Lala S, Ogura Y, Osborne C, Hor SY, Bromfield A, Davies S, Ogunbiyi O, Nunez G, Keshav S: Crohn's disease and the NOD2 gene: A role for Paneth cells. Gastroenterology 2003; 125: 47-57. (Pubitemid 36799106)
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 47-57
-
-
Lala, S.1
Ogura, Y.2
Osborne, C.3
Hor, S.Y.4
Bromfield, A.5
Davies, S.6
Ogunbiyi, O.7
Nunez, G.8
Keshav, S.9
-
47
-
-
0037380969
-
CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells
-
Hisamatsu T, Suzuki M, Reinecker HC, Nadeau WJ, McCormick BA, Podolsky DK: CARD15/NOD2 functions as an antibacterial factor in human intestinal epithelial cells. Gastroenterology 2003; 124: 993-1000.
-
(2003)
Gastroenterology
, vol.124
, pp. 993-1000
-
-
Hisamatsu, T.1
Suzuki, M.2
Reinecker, H.C.3
Nadeau, W.J.4
McCormick, B.A.5
Podolsky, D.K.6
-
48
-
-
10744222688
-
Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis
-
DOI 10.1136/gut.52.11.1591
-
Ogura Y, Lala S, Xin W, Smith E, Dowds TA, Chen FF, Zimmermann E, Tretiakova M, Cho JH, Hart J, Greenson JK, Keshav S, Nunez G: Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis. Gut 2003; 52: 1591-1597. (Pubitemid 37363443)
-
(2003)
Gut
, vol.52
, Issue.11
, pp. 1591-1597
-
-
Ogura, Y.1
Lala, S.2
Xin, W.3
Smith, E.4
Dowds, T.A.5
Chen, F.F.6
Zimmermann, E.7
Tretiakova, M.8
Cho, J.H.9
Hart, J.10
Greenson, J.K.11
Keshav, S.12
Nunez, G.13
-
49
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
Tanabe T, Chamaillard M, Ogura Y, Zhu L, Qiu S, Masumoto J, Ghosh P, Moran A, Predergast MM, Tromp G, Williams CJ, Inohara N, Nunez G: Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition. EMBO J 2004; 23: 1587-1597.
-
(2004)
EMBO J
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
Chamaillard, M.2
Ogura, Y.3
Zhu, L.4
Qiu, S.5
Masumoto, J.6
Ghosh, P.7
Moran, A.8
Predergast, M.M.9
Tromp, G.10
Williams, C.J.11
Inohara, N.12
Nunez, G.13
-
50
-
-
33749266363
-
Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop
-
Begue B, Dumant C, Bambou JC, Beaulieu JF, Chamaillard M, Hugot JP, Goulet O, Schmitz J, Philpott DJ, Cerf-Bensussan N, Ruemmele FM: Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop. J Cell Physiol 2006; 209: 241-252.
-
(2006)
J Cell Physiol
, vol.209
, pp. 241-252
-
-
Begue, B.1
Dumant, C.2
Bambou, J.C.3
Beaulieu, J.F.4
Chamaillard, M.5
Hugot, J.P.6
Goulet, O.7
Schmitz, J.8
Philpott, D.J.9
Cerf-Bensussan, N.10
Ruemmele, F.M.11
-
51
-
-
0037458665
-
Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease
-
Inohara N, Ogura Y, Fontalba A, Gutierrez O, Pons F, Crespo J, Fukase K, Inamura S, Kusumoto S, Hashimoto M, Foster SJ, Moran AP, Fernandez-Luna JL, Nunez G: Host recognition of bacterial muramyl dipeptide mediated through NOD2. Implications for Crohn's disease. J Biol Chem 2003; 278: 5509-5512.
-
(2003)
J Biol Chem
, vol.278
, pp. 5509-5512
-
-
Inohara, N.1
Ogura, Y.2
Fontalba, A.3
Gutierrez, O.4
Pons, F.5
Crespo, J.6
Fukase, K.7
Inamura, S.8
Kusumoto, S.9
Hashimoto, M.10
Foster, S.J.11
Moran, A.P.12
Fernandez-Luna, J.L.13
Nunez, G.14
-
52
-
-
13244292161
-
NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G, Flavell RA: NOD2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005; 307: 731-734.
-
(2005)
Science
, vol.307
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
53
-
-
13244277880
-
NOD2 mutation in Crohn's disease potentiates NF-- B activity and IL-1- processing
-
Maeda S, Hsu LC, Liu H, Bankston LA, Iimura M, Kagnoff MF, Eckmann L, Karin M: NOD2 mutation in Crohn's disease potentiates NF-- B activity and IL-1- processing. Science 2005; 307: 734-738.
-
(2005)
Science
, vol.307
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
54
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal- -defensin expression
-
Wehkamp J, Harder J, Weichenthal M, Schwab M, Schaffeler E, Schlee M, Herrlinger KR, Stallmach A, Noack F, Fritz P, Schroder JM, Bevins CL, Fellermann K, Stange EF: NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal- -defensin expression. Gut 2004; 53: 1658-1664.
-
(2004)
Gut
, vol.53
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
Schwab, M.4
Schaffeler, E.5
Schlee, M.6
Herrlinger, K.R.7
Stallmach, A.8
Noack, F.9
Fritz, P.10
Schroder, J.M.11
Bevins, C.L.12
Fellermann, K.13
Stange, E.F.14
-
55
-
-
17744373329
-
Genetics of Crohn disease, an archetypal inflammatory barrier disease
-
DOI 10.1038/nrg1607
-
Schreiber S, Rosenstiel P, Albrecht M, Hampe J, Krawczak M: Genetics of Crohn's disease, an archetypal inflammatory barrier disease. Nat Rev Genet 2005; 6: 376-388. (Pubitemid 40577181)
-
(2005)
Nature Reviews Genetics
, vol.6
, Issue.5
, pp. 376-388
-
-
Schreiber, S.1
Rosenstiel, P.2
Albrecht, M.3
Hampe, J.4
Krawczak, M.5
-
56
-
-
0033910870
-
Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
-
Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, McLeod RS, Griffiths AM, Green T, Brettin TS, Stone V, Bull SB, Bitton A, Williams CN, Greenberg GR, Cohen Z, Lander ES, Hudson TJ, Siminovitch KA: Genomewide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci. Am J Hum Genet 2000; 66: 1863-1870.
-
(2000)
Am J Hum Genet
, vol.66
, pp. 1863-1870
-
-
Rioux, J.D.1
Silverberg, M.S.2
Daly, M.J.3
Steinhart, A.H.4
McLeod, R.S.5
Griffiths, A.M.6
Green, T.7
Brettin, T.S.8
Stone, V.9
Bull, S.B.10
Bitton, A.11
Williams, C.N.12
Greenberg, G.R.13
Cohen, Z.14
Lander, E.S.15
Hudson, T.J.16
Siminovitch, K.A.17
-
57
-
-
0033228538
-
A genome-wide search identifies potential new susceptibility loci for Crohn's disease
-
Ma Y, Ohmen JD, Li Z, Bentley LG, McElree C, Pressman S, Targan SR, Fischel-Ghodsian N, Rotter JI, Yang H: A genome-wide search identifies potential new susceptibility loci for Crohn's disease. Inflamm Bowel Dis 1999; 5: 271-278.
-
(1999)
Inflamm Bowel Dis
, vol.5
, pp. 271-278
-
-
Ma, Y.1
Ohmen, J.D.2
Li, Z.3
Bentley, L.G.4
McElree, C.5
Pressman, S.6
Targan, S.R.7
Fischel-Ghodsian, N.8
Rotter, J.I.9
Yang, H.10
-
58
-
-
66149176307
-
The expanding universe of inflammatory bowel disease genetics
-
Achkar JP, Duerr R: The expanding universe of inflammatory bowel disease genetics. Curr Opin Gastroenterol 2008; 24: 429-434.
-
(2008)
Curr Opin Gastroenterol
, vol.24
, pp. 429-434
-
-
Achkar, J.P.1
Duerr, R.2
-
59
-
-
0034785352
-
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
-
Rioux JD, Daly MJ, Silverberg MS, Lindblad K, Steinhart H, Cohen Z, Delmonte T, Kocher K, Miller K, Guschwan S, Kulbokas EJ, O'Leary S, Winchester E, Dewar K, Green T, Stone V, Chow C, Cohen A, Langelier D, Lapointe G, Gaudet D, Faith J, Branco N, Bull SB, McLeod RS, Griffiths AM, Bitton A, Greenberg GR, Lander ES, Siminovitch KA, Hudson TJ: Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet 2001; 29: 223-228.
-
(2001)
Nat Genet
, vol.29
, pp. 223-228
-
-
Rioux, J.D.1
Daly, M.J.2
Silverberg, M.S.3
Lindblad, K.4
Steinhart, H.5
Cohen, Z.6
Delmonte, T.7
Kocher, K.8
Miller, K.9
Guschwan, S.10
Kulbokas, E.J.11
O'Leary, S.12
Winchester, E.13
Dewar, K.14
Green, T.15
Stone, V.16
Chow, C.17
Cohen, A.18
Langelier, D.19
Lapointe, G.20
Gaudet, D.21
Faith, J.22
Branco, N.23
Bull, S.B.24
McLeod, R.S.25
Griffiths, A.M.26
Bitton, A.27
Greenberg, G.R.28
Lander, E.S.29
Siminovitch, K.A.30
Hudson, T.J.31
more..
-
60
-
-
0034791035
-
High-resolution haplotype structure in the human genome
-
Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES: High-resolution haplotype structure in the human genome. Nat Genet 2001; 29: 229-232.
-
(2001)
Nat Genet
, vol.29
, pp. 229-232
-
-
Daly, M.J.1
Rioux, J.D.2
Schaffner, S.F.3
Hudson, T.J.4
Lander, E.S.5
-
61
-
-
0344364566
-
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
-
Tokuhiro S, Yamada R, Chang X, Suzuki A, Kochi Y, Sawada T, Suzuki M, Nagasaki M, Ohtsuki M, Ono M, Furukawa H, Nagashima M, Yoshino S, Mabuchi A, Sekine A, Saito S, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K: An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis. Nat Genet 2003; 35: 341-348.
-
(2003)
Nat Genet
, vol.35
, pp. 341-348
-
-
Tokuhiro, S.1
Yamada, R.2
Chang, X.3
Suzuki, A.4
Kochi, Y.5
Sawada, T.6
Suzuki, M.7
Nagasaki, M.8
Ohtsuki, M.9
Ono, M.10
Furukawa, H.11
Nagashima, M.12
Yoshino, S.13
Mabuchi, A.14
Sekine, A.15
Saito, S.16
Takahashi, A.17
Tsunoda, T.18
Nakamura, Y.19
Yamamoto, K.20
more..
-
62
-
-
0033921479
-
Structure of renal organic anion and cation transporters
-
Burckhardt G, Wolff NA: Structure of renal organic anion and cation transporters. Am J Physiol Renal Physiol 2000; 278:F853-F866.
-
(2000)
Am J Physiol Renal Physiol
, vol.278
-
-
Burckhardt, G.1
Wolff, N.A.2
-
63
-
-
17044437751
-
Discovery of the ergothioneine transporter
-
Grundemann D, Harlfinger S, Golz S, Geerts A, Lazar A, Berkels R, Jung N, Rubbert A, Schomig E: Discovery of the ergothioneine transporter. Proc Natl Acad Sci USA 2005; 102: 5256-5261.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 5256-5261
-
-
Grundemann, D.1
Harlfinger, S.2
Golz, S.3
Geerts, A.4
Lazar, A.5
Berkels, R.6
Jung, N.7
Rubbert, A.8
Schomig, E.9
-
64
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn's disease
-
Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St George-Hyslop PH, Siminovitch KA: Functional variants of OCTN cation transporter genes are associated with Crohn's disease. Nat Genet 2004; 36: 471-475.
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
Newman, B.7
Van Oene, M.8
Cescon, D.9
Greenberg, G.10
Griffiths, A.M.11
St George-Hyslop, P.H.12
Siminovitch, K.A.13
-
65
-
-
14944356373
-
A risk haplotype in the solute carrier family 22A4/ 22A5 gene cluster influences phenotypic expression of Crohn's disease
-
Newman B, Gu X, Wintle R, Cescon D, Yazdanpanah M, Liu X, Peltekova V, Van Oene M, Amos CI, Siminovitch KA: A risk haplotype in the solute carrier family 22A4/ 22A5 gene cluster influences phenotypic expression of Crohn's disease. Gastroenterology 2005; 128: 260-269.
-
(2005)
Gastroenterology
, vol.128
, pp. 260-269
-
-
Newman, B.1
Gu, X.2
Wintle, R.3
Cescon, D.4
Yazdanpanah, M.5
Liu, X.6
Peltekova, V.7
Van Oene, M.8
Amos, C.I.9
Siminovitch, K.A.10
-
66
-
-
21344449654
-
Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease
-
Torok HP, Glas J, Tonenchi L, Lohse P, Muller- Myhsok B, Limbersky O, Neugebauer C, Schnitzler F, Seiderer J, Tillack C, Brand S, Brunnler G, Jagiello P, Epplen JT, Griga T, Klein W, Schiemann U, Folwaczny M, Ochsenkuhn T, Folwaczny C: Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut 2005; 54: 1421-1427.
-
(2005)
Gut
, vol.54
, pp. 1421-1427
-
-
Torok, H.P.1
Glas, J.2
Tonenchi, L.3
Lohse, P.4
Muller- Myhsok, B.5
Limbersky, O.6
Neugebauer, C.7
Schnitzler, F.8
Seiderer, J.9
Tillack, C.10
Brand, S.11
Brunnler, G.12
Jagiello, P.13
Epplen, J.T.14
Griga, T.15
Klein, W.16
Schiemann, U.17
Folwaczny, M.18
Ochsenkuhn, T.19
Folwaczny, C.20
more..
-
67
-
-
33746935094
-
Direct or indirect association in a complex disease: The role of SLC22A4 and SLC22A5 functional variants in Crohn disease
-
Fisher SA, Hampe J, Onnie CM, Daly MJ, Curley C, Purcell S, Sanderson J, Mansfield J, Annese V, Forbes A, Lewis CM, Schreiber S, Rioux JD, Mathew CG: Direct or indirect association in a complex disease: The role of SLC22A4 and SLC22A5 functional variants in Crohn disease. Hum Mutat 2006; 27: 778-785.
-
(2006)
Hum Mutat
, vol.27
, pp. 778-785
-
-
Fisher, S.A.1
Hampe, J.2
Onnie, C.M.3
Daly, M.J.4
Curley, C.5
Purcell, S.6
Sanderson, J.7
Mansfield, J.8
Annese, V.9
Forbes, A.10
Lewis, C.M.11
Schreiber, S.12
Rioux, J.D.13
Mathew, C.G.14
-
68
-
-
28844509940
-
The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease
-
Noble CL, Nimmo ER, Drummond H, Ho GT, Tenesa A, Smith L, Anderson N, Arnott ID, Satsangi J: The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease. Gastroenterology 2005; 129: 1854-1864.
-
(2005)
Gastroenterology
, vol.129
, pp. 1854-1864
-
-
Noble, C.L.1
Nimmo, E.R.2
Drummond, H.3
Ho, G.T.4
Tenesa, A.5
Smith, L.6
Anderson, N.7
Arnott, I.D.8
Satsangi, J.9
-
69
-
-
33646779514
-
Evidence for association of OCTN genes and IBD5 with ulcerative colitis
-
Waller S, Tremelling M, Bredin F, Godfrey L, Howson J, Parkes M: Evidence for association of OCTN genes and IBD5 with ulcerative colitis. Gut 2006; 55: 809-814.
-
(2006)
Gut
, vol.55
, pp. 809-814
-
-
Waller, S.1
Tremelling, M.2
Bredin, F.3
Godfrey, L.4
Howson, J.5
Parkes, M.6
-
70
-
-
0037383554
-
Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease
-
Mirza MM, Fisher SA, King K, Cuthbert AP, Hampe J, Sanderson J, Mansfield J, Donaldson P, Macpherson AJ, Forbes A, Schreiber S, Lewis CM, Mathew CG: Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease. Am J Hum Genet 2003; 72: 1018-1022.
-
(2003)
Am J Hum Genet
, vol.72
, pp. 1018-1022
-
-
Mirza, M.M.1
Fisher, S.A.2
King, K.3
Cuthbert, A.P.4
Hampe, J.5
Sanderson, J.6
Mansfield, J.7
Donaldson, P.8
MacPherson, A.J.9
Forbes, A.10
Schreiber, S.11
Lewis, C.M.12
Mathew, C.G.13
-
71
-
-
0142138025
-
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease
-
Negoro K, McGovern DP, Kinouchi Y, Takahashi S, Lench NJ, Shimosegawa T, Carey A, Cardon LR, Jewell DP, van Heel DA: Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease. Gut 2003; 52: 541-546.
-
(2003)
Gut
, vol.52
, pp. 541-546
-
-
Negoro, K.1
McGovern, D.P.2
Kinouchi, Y.3
Takahashi, S.4
Lench, N.J.5
Shimosegawa, T.6
Carey, A.7
Cardon, L.R.8
Jewell, D.P.9
Van Heel, D.A.10
-
72
-
-
0038389762
-
IBD5 is a general risk factor for inflammatory bowel disease: Replication of association with Crohn's disease and identification of a novel association with ulcerative colitis
-
Giallourakis C, Stoll M, Miller K, Hampe J, Lander ES, Daly MJ, Schreiber S, Rioux JD: IBD5 is a general risk factor for inflammatory bowel disease: Replication of association with Crohn's disease and identification of a novel association with ulcerative colitis. Am J Hum Genet 2003; 73: 205-211.
-
(2003)
Am J Hum Genet
, vol.73
, pp. 205-211
-
-
Giallourakis, C.1
Stoll, M.2
Miller, K.3
Hampe, J.4
Lander, E.S.5
Daly, M.J.6
Schreiber, S.7
Rioux, J.D.8
-
73
-
-
33644910915
-
Contribution of IBD5 locus to clinical features of IBD patients
-
Latiano A, Palmieri O, Valvano RM, D'Inca R, Vecchi M, Ferraris A, Sturniolo GC, Spina L, Lombardi G, Dallapiccola B, Andriulli A, Devoto M, Annese V: Contribution of IBD5 locus to clinical features of IBD patients. Am J Gastroenterol 2006; 101: 318-325.
-
(2006)
Am J Gastroenterol
, vol.101
, pp. 318-325
-
-
Latiano, A.1
Palmieri, O.2
Valvano, R.M.3
D'Inca, R.4
Vecchi, M.5
Ferraris, A.6
Sturniolo, G.C.7
Spina, L.8
Lombardi, G.9
Dallapiccola, B.10
Andriulli, A.11
Devoto, M.12
Annese, V.13
-
74
-
-
31144473386
-
Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease
-
Gazouli M, Mantzaris G, Archimandritis AJ, Nasioulas G, Anagnou NP: Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease. World J Gastroenterol 2005; 11: 7525-7530.
-
(2005)
World J Gastroenterol
, vol.11
, pp. 7525-7530
-
-
Gazouli, M.1
Mantzaris, G.2
Archimandritis, A.J.3
Nasioulas, G.4
Anagnou, N.P.5
-
75
-
-
33847212513
-
Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease
-
Silverberg MS, Duerr RH, Brant SR, Bromfield G, Datta LW, Jani N, Kane SV, Rotter JI, Philip Schumm L, Hillary Steinhart A, Taylor KD, Yang H, Cho JH, Rioux JD, Daly MJ: Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease. Eur J Hum Genet 2007; 15: 328-335.
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 328-335
-
-
Silverberg, M.S.1
Duerr, R.H.2
Brant, S.R.3
Bromfield, G.4
Datta, L.W.5
Jani, N.6
Kane, S.V.7
Rotter, J.I.8
Philip Schumm, L.9
Hillary Steinhart, A.10
Taylor, K.D.11
Yang, H.12
Cho, J.H.13
Rioux, J.D.14
Daly, M.J.15
-
76
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Gunther S, Prescott NJ, Onnie CM, Hasler R, Sipos B, Folsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S: A genome-wide association scan of nonsynonymous SNPS identifies a susceptibility variant for Crohn disease in Atg16L1. Nat Genet 2007; 39: 207-211. (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
77
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
78
-
-
35548958718
-
Genome-wide association study for Crohn's disease in the Quebec founder population identifies multiple validated disease loci
-
Raelson JV, Little RD, Ruether A, Fournier H, Paquin B, Van Eerdewegh P, Bradley WE, Croteau P, Nguyen-Huu Q, Segal J, Debrus S, Allard R, Rosenstiel P, Franke A, Jacobs G, Nikolaus S, Vidal JM, Szego P, Laplante N, Clark HF, Paulussen RJ, Hooper JW, Keith TP, Belouchi A, Schreiber S: Genome-wide association study for Crohn's disease in the Quebec founder population identifies multiple validated disease loci. Proc Natl Acad Sci USA 2007; 104: 14747-14752.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14747-14752
-
-
Raelson, J.V.1
Little, R.D.2
Ruether, A.3
Fournier, H.4
Paquin, B.5
Van Eerdewegh, P.6
Bradley, W.E.7
Croteau, P.8
Nguyen-Huu, Q.9
Segal, J.10
Debrus, S.11
Allard, R.12
Rosenstiel, P.13
Franke, A.14
Jacobs, G.15
Nikolaus, S.16
Vidal, J.M.17
Szego, P.18
Laplante, N.19
Clark, H.F.20
Paulussen, R.J.21
Hooper, J.W.22
Keith, T.P.23
Belouchi, A.24
Schreiber, S.25
more..
-
79
-
-
29744459145
-
Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease
-
Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, Hiwatashi N, Takahashi S, Shimosegawa T: Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease. Scand J Gastroenterol 2006; 41: 48-53.
-
(2006)
Scand J Gastroenterol
, vol.41
, pp. 48-53
-
-
Tosa, M.1
Negoro, K.2
Kinouchi, Y.3
Abe, H.4
Nomura, E.5
Takagi, S.6
Aihara, H.7
Oomori, S.8
Sugimura, M.9
Takahashi, K.10
Hiwatashi, N.11
Takahashi, S.12
Shimosegawa, T.13
-
80
-
-
12744274602
-
Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease
-
Yamazaki K, Takazoe M, Tanaka T, Ichimori T, Saito S, Iida A, Onouchi Y, Hata A, Nakamura Y: Association analysis of SLC22A4, SLC22A5 and DLG5 in Japanese patients with Crohn disease. J Hum Genet 2004; 49: 664-668.
-
(2004)
J Hum Genet
, vol.49
, pp. 664-668
-
-
Yamazaki, K.1
Takazoe, M.2
Tanaka, T.3
Ichimori, T.4
Saito, S.5
Iida, A.6
Onouchi, Y.7
Hata, A.8
Nakamura, Y.9
-
81
-
-
33644924311
-
Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis
-
Palmieri O, Latiano A, Valvano R, D'Inca R, Vecchi M, Sturniolo GC, Saibeni S, Peyvandi F, Bossa F, Zagaria C, Andriulli A, Devoto M, Annese V: Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 2006; 23: 497-506.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 497-506
-
-
Palmieri, O.1
Latiano, A.2
Valvano, R.3
D'Inca, R.4
Vecchi, M.5
Sturniolo, G.C.6
Saibeni, S.7
Peyvandi, F.8
Bossa, F.9
Zagaria, C.10
Andriulli, A.11
Devoto, M.12
Annese, V.13
-
82
-
-
10744227039
-
The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease- associated variants
-
Van Heel DA, Dechairo BM, Dawson G, Mc- Govern DP, Negoro K, Carey AH, Cardon LR, Mackay I, Jewell DP, Lench NJ: The IBD6 Crohn's disease locus demonstrates complex interactions with CARD15 and IBD5 disease- associated variants. Hum Mol Genet 2003; 12: 2569-2575.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2569-2575
-
-
Van Heel, D.A.1
Dechairo, B.M.2
Dawson, G.3
Mc- Govern, D.P.4
Negoro, K.5
Carey, A.H.6
Cardon, L.R.7
MacKay, I.8
Jewell, D.P.9
Lench, N.J.10
-
83
-
-
0037622913
-
Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31
-
Armuzzi A, Ahmad T, Ling KL, de Silva A, Cullen S, van Heel D, Orchard TR, Welsh KI, Marshall SE, Jewell DP: Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31. Gut 2003; 52: 1133-1139.
-
(2003)
Gut
, vol.52
, pp. 1133-1139
-
-
Armuzzi, A.1
Ahmad, T.2
Ling, K.L.3
De Silva, A.4
Cullen, S.5
Van Heel, D.6
Orchard, T.R.7
Welsh, K.I.8
Marshall, S.E.9
Jewell, D.P.10
-
84
-
-
37349020216
-
Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease
-
Onnie CM, Fisher SA, Prescott NJ, Mirza MM, Green P, Sanderson J, Forbes A, Lewis CM, Mathew CG: Diverse effects of the CARD15 and IBD5 loci on clinical phenotype in 630 patients with Crohn's disease. Eur J Gastroenterol Hepatol 2008; 20: 37-45.
-
(2008)
Eur J Gastroenterol Hepatol
, vol.20
, pp. 37-45
-
-
Onnie, C.M.1
Fisher, S.A.2
Prescott, N.J.3
Mirza, M.M.4
Green, P.5
Sanderson, J.6
Forbes, A.7
Lewis, C.M.8
Mathew, C.G.9
-
86
-
-
16044373177
-
Two stage genomewide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
-
Satsangi J, Parkes M, Louis E, Hashimoto L, Kato N, Welsh K, Terwilliger JD, Lathrop GM, Bell JI, Jewell DP: Two stage genomewide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet 1996; 14: 199-202.
-
(1996)
Nat Genet
, vol.14
, pp. 199-202
-
-
Satsangi, J.1
Parkes, M.2
Louis, E.3
Hashimoto, L.4
Kato, N.5
Welsh, K.6
Terwilliger, J.D.7
Lathrop, G.M.8
Bell, J.I.9
Jewell, D.P.10
-
87
-
-
22844438782
-
The G2964A polymorphism of the STAT6 gene in inflammatory bowel disease
-
Klein W, Tromm A, Folwaczny C, Hagedorn M, Duerig N, Epplen J, Schmiegel W, Griga T: The G2964A polymorphism of the STAT6 gene in inflammatory bowel disease. Dig Liver Dis 2005; 37: 159-161.
-
(2005)
Dig Liver Dis
, vol.37
, pp. 159-161
-
-
Klein, W.1
Tromm, A.2
Folwaczny, C.3
Hagedorn, M.4
Duerig, N.5
Epplen, J.6
Schmiegel, W.7
Griga, T.8
-
88
-
-
0032231756
-
Linkage and association between inflammatory bowel disease and a locus on chromosome 12
-
Duerr RH, Barmada MM, Zhang L, Davis S, Preston RA, Chensny LJ, Brown JL, Ehrlich GD, Weeks DE, Aston CE: Linkage and association between inflammatory bowel disease and a locus on chromosome 12. Am J Hum Genet 1998; 63: 95-100.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 95-100
-
-
Duerr, R.H.1
Barmada, M.M.2
Zhang, L.3
Davis, S.4
Preston, R.A.5
Chensny, L.J.6
Brown, J.L.7
Ehrlich, G.D.8
Weeks, D.E.9
Aston, C.E.10
-
89
-
-
17144456849
-
Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16
-
Curran ME, Lau KF, Hampe J, Schreiber S, Bridger S, Macpherson AJ, Cardon LR, Sakul H, Harris TJ, Stokkers P, Van Deventer SJ, Mirza M, Raedler A, Kruis W, Meckler U, Theuer D, Herrmann T, Gionchetti P, Lee J, Mathew C, Lennard-Jones J: Genetic analysis of inflammatory bowel disease in a large European cohort supports linkage to chromosomes 12 and 16. Gastroenterology 1998; 115: 1066-1071.
-
(1998)
Gastroenterology
, vol.115
, pp. 1066-1071
-
-
Curran, M.E.1
Lau, K.F.2
Hampe, J.3
Schreiber, S.4
Bridger, S.5
MacPherson, A.J.6
Cardon, L.R.7
Sakul, H.8
Harris, T.J.9
Stokkers, P.10
Van Deventer, S.J.11
Mirza, M.12
Raedler, A.13
Kruis, W.14
Meckler, U.15
Theuer, D.16
Herrmann, T.17
Gionchetti, P.18
Lee, J.19
Mathew, C.20
Lennard-Jones, J.21
more..
-
90
-
-
0036888864
-
Association of ulcerative colitis with the inflammatory bowel disease susceptibility locus IBD2 in non-Jewish Caucasians and evidence of genetic heterogeneity among racial and ethnic populations with Crohn disease
-
Uthoff SM, Crawford NP, Eichenberger MR, Hamilton CJ, Petras RE, Martin ER, Galandiuk S: Association of ulcerative colitis with the inflammatory bowel disease susceptibility locus IBD2 in non-Jewish Caucasians and evidence of genetic heterogeneity among racial and ethnic populations with Crohn disease. Am J Med Genet 2002; 113: 242-249.
-
(2002)
Am J Med Genet
, vol.113
, pp. 242-249
-
-
Uthoff, S.M.1
Crawford, N.P.2
Eichenberger, M.R.3
Hamilton, C.J.4
Petras, R.E.5
Martin, E.R.6
Galandiuk, S.7
-
91
-
-
3042657319
-
Genome-wide scan in a Flemish inflammatory bowel disease population: Support for the IBD4 locus, population heterogeneity, and epistasis
-
Vermeire S, Rutgeerts P, Van Steen K, Joossens S, Claessens G, Pierik M, Peeters M, Vlietinck R: Genome-wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis. Gut 2004; 53: 980-986.
-
(2004)
Gut
, vol.53
, pp. 980-986
-
-
Vermeire, S.1
Rutgeerts, P.2
Van Steen, K.3
Joossens, S.4
Claessens, G.5
Pierik, M.6
Peeters, M.7
Vlietinck, R.8
-
92
-
-
0036716702
-
Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease
-
Schreiber S, Rosenstiel P, Hampe J, Nikolaus S, Groessner B, Schottelius A, Kuhbacher T, Hamling J, Folsch UR, Seegert D: Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease. Gut 2002; 51: 379-385.
-
(2002)
Gut
, vol.51
, pp. 379-385
-
-
Schreiber, S.1
Rosenstiel, P.2
Hampe, J.3
Nikolaus, S.4
Groessner, B.5
Schottelius, A.6
Kuhbacher, T.7
Hamling, J.8
Folsch, U.R.9
Seegert, D.10
-
93
-
-
0242441469
-
No evidence for involvement of IL-4r and CD11b from the IBD1 region and STAT6 in the IBD2 region in Crohn's disease
-
De Jong DJ, Franke B, Naber AH, Willemen JJ, Heister AJ, Brunner HG, de Kovel CG, Hol FA: No evidence for involvement of IL-4r and CD11b from the IBD1 region and STAT6 in the IBD2 region in Crohn's disease. Eur J Hum Genet 2003; 11: 884-887.
-
(2003)
Eur J Hum Genet
, vol.11
, pp. 884-887
-
-
De Jong, D.J.1
Franke, B.2
Naber, A.H.3
Willemen, J.J.4
Heister, A.J.5
Brunner, H.G.6
De Kovel, C.G.7
Hol, F.A.8
-
94
-
-
4644265283
-
Mapping of a disease susceptibility locus in chromosome 6p in Japanese patients with ulcerative colitis
-
Nomura E, Kinouchi Y, Negoro K, Kojima Y, Oomori S, Sugimura M, Hiroki M, Takagi S, Aihara H, Takahashi S, Hiwatashi N, Shimosegawa T: Mapping of a disease susceptibility locus in chromosome 6p in Japanese patients with ulcerative colitis. Genes Immun 2004; 5: 477-483.
-
(2004)
Genes Immun
, vol.5
, pp. 477-483
-
-
Nomura, E.1
Kinouchi, Y.2
Negoro, K.3
Kojima, Y.4
Oomori, S.5
Sugimura, M.6
Hiroki, M.7
Takagi, S.8
Aihara, H.9
Takahashi, S.10
Hiwatashi, N.11
Shimosegawa, T.12
-
95
-
-
0032926240
-
Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses
-
Yang H, Plevy SE, Taylor K, Tyan D, Fischel- Ghodsian N, McElree C, Targan SR, Rotter JI: Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple non-parametric analyses. Gut 1999; 44: 519-526.
-
(1999)
Gut
, vol.44
, pp. 519-526
-
-
Yang, H.1
Plevy, S.E.2
Taylor, K.3
Tyan, D.4
Fischel- Ghodsian, N.5
McElree, C.6
Targan, S.R.7
Rotter, J.I.8
-
96
-
-
0030007093
-
Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease
-
Satsangi J, Welsh KI, Bunce M, Julier C, Farrant JM, Bell JI, Jewell DP: Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 1996; 347: 1212-1217.
-
(1996)
Lancet
, vol.347
, pp. 1212-1217
-
-
Satsangi, J.1
Welsh, K.I.2
Bunce, M.3
Julier, C.4
Farrant, J.M.5
Bell, J.I.6
Jewell, D.P.7
-
97
-
-
0032708293
-
Amino acid polymorphism at residue 71 in HLADR- chain plays a critical role in susceptibility to ulcerative colitis
-
De la Concha EG, Fernandez-Arquero M, Martinez A, Vigil P, Vidal F, Lopez-Nava G, Diaz-Rubio M, Garcia-Paredes J: Amino acid polymorphism at residue 71 in HLADR- chain plays a critical role in susceptibility to ulcerative colitis. Dig Dis Sci 1999; 44: 2324-2329.
-
(1999)
Dig Dis Sci
, vol.44
, pp. 2324-2329
-
-
De La Concha, E.G.1
Fernandez-Arquero, M.2
Martinez, A.3
Vigil, P.4
Vidal, F.5
Lopez-Nava, G.6
Diaz-Rubio, M.7
Garcia-Paredes, J.8
-
98
-
-
0030912011
-
Genetic markers may predict disease behavior in patients with ulcerative colitis
-
Roussomoustakaki M, Satsangi J, Welsh K, Louis E, Fanning G, Targan S, Landers C, Jewell DP: Genetic markers may predict disease behavior in patients with ulcerative colitis. Gastroenterology 1997; 112: 1845-1853.
-
(1997)
Gastroenterology
, vol.112
, pp. 1845-1853
-
-
Roussomoustakaki, M.1
Satsangi, J.2
Welsh, K.3
Louis, E.4
Fanning, G.5
Targan, S.6
Landers, C.7
Jewell, D.P.8
-
99
-
-
58849161728
-
Clinical and molecular characteristics of isolated colonic Crohn's disease
-
Hancock L, Beckly J, Geremia A, Cooney R, Cummings F, Pathan S, Guo C, Warren BF, Mortensen N, Ahmad T, Jewell D: Clinical and molecular characteristics of isolated colonic Crohn's disease. Inflamm Bowel Dis 2008; 14: 1667-1677.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 1667-1677
-
-
Hancock, L.1
Beckly, J.2
Geremia, A.3
Cooney, R.4
Cummings, F.5
Pathan, S.6
Guo, C.7
Warren, B.F.8
Mortensen, N.9
Ahmad, T.10
Jewell, D.11
-
100
-
-
9144231967
-
IBD1 and IBD3 determine location of Crohn's disease in the Spanish population
-
Fernandez L, Mendoza JL, Martinez A, Urcelay E, Fernandez-Arquero M, Garcia- Paredes J, Pena AS, Diaz-Rubio M, de la Concha EG: IBD1 and IBD3 determine location of Crohn's disease in the Spanish population. Inflamm Bowel Dis 2004; 10: 715-722.
-
(2004)
Inflamm Bowel Dis
, vol.10
, pp. 715-722
-
-
Fernandez, L.1
Mendoza, J.L.2
Martinez, A.3
Urcelay, E.4
Fernandez-Arquero, M.5
Garcia- Paredes, J.6
Pena, A.S.7
Diaz-Rubio, M.8
De La Concha, E.G.9
-
101
-
-
33745439458
-
Genetics of inflammatory bowel disease: The role of the HLA complex
-
Ahmad T, Marshall SE, Jewell D: Genetics of inflammatory bowel disease: the role of the HLA complex. World J Gastroenterol 2006; 12: 3628-3635.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 3628-3635
-
-
Ahmad, T.1
Marshall, S.E.2
Jewell, D.3
-
102
-
-
10744221095
-
CARD15 and HLA-DRB1 alleles influence susceptibility and disease localization in Crohn's disease
-
Newman B, Silverberg MS, Gu X, Zhang Q, Lazaro A, Steinhart AH, Greenberg GR, Griffiths AM, McLeod RS, Cohen Z, Fernandez- Vina M, Amos CI, Siminovitch K: CARD15 and HLA-DRB1 alleles influence susceptibility and disease localization in Crohn's disease. Am J Gastroenterol 2004; 99: 306-315.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 306-315
-
-
Newman, B.1
Silverberg, M.S.2
Gu, X.3
Zhang, Q.4
Lazaro, A.5
Steinhart, A.H.6
Greenberg, G.R.7
Griffiths, A.M.8
McLeod, R.S.9
Cohen, Z.10
Fernandez- Vina, M.11
Amos, C.I.12
Siminovitch, K.13
-
103
-
-
0033973568
-
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
-
Orchard TR, Thiyagaraja S, Welsh KI, Wordsworth BP, Hill Gaston JS, Jewell DP: Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease. Gastroenterology 2000; 118: 274-278.
-
(2000)
Gastroenterology
, vol.118
, pp. 274-278
-
-
Orchard, T.R.1
Thiyagaraja, S.2
Welsh, K.I.3
Wordsworth, B.P.4
Hill Gaston, J.S.5
Jewell, D.P.6
-
104
-
-
18444395237
-
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-- B transcription factors
-
Van Heel DA, Udalova IA, De Silva AP, Mc- Govern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D: Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-- B transcription factors. Hum Mol Genet 2002; 11: 1281-1289.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1281-1289
-
-
Van Heel, D.A.1
Udalova, I.A.2
De Silva, A.P.3
Mc- Govern, D.P.4
Kinouchi, Y.5
Hull, J.6
Lench, N.J.7
Cardon, L.R.8
Carey, A.H.9
Jewell, D.P.10
Kwiatkowski, D.11
-
105
-
-
33645105960
-
Genetic variants in TNF-- but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort
-
Tremelling M, Waller S, Bredin F, Greenfield S, Parkes M: Genetic variants in TNF-- but not DLG5 are associated with inflammatory bowel disease in a large United Kingdom cohort. Inflamm Bowel Dis 2006; 12: 178-184.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 178-184
-
-
Tremelling, M.1
Waller, S.2
Bredin, F.3
Greenfield, S.4
Parkes, M.5
-
106
-
-
0036731117
-
Uveitis and erythema nodosum in inflammatory bowel disease: Clinical features and the role of HLA genes
-
Orchard TR, Chua CN, Ahmad T, Cheng H, Welsh KI, Jewell DP: Uveitis and erythema nodosum in inflammatory bowel disease: clinical features and the role of HLA genes. Gastroenterology 2002; 123: 714-718.
-
(2002)
Gastroenterology
, vol.123
, pp. 714-718
-
-
Orchard, T.R.1
Chua, C.N.2
Ahmad, T.3
Cheng, H.4
Welsh, K.I.5
Jewell, D.P.6
-
107
-
-
48349136889
-
Genomewide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwilliam R, Tremelling M, Deloukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ: Genomewide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008; 40: 955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
Brant, S.R.7
Silverberg, M.S.8
Taylor, K.D.9
Barmada, M.M.10
Bitton, A.11
Dassopoulos, T.12
Datta, L.W.13
Green, T.14
Griffiths, A.M.15
Kistner, E.O.16
Murtha, M.T.17
Regueiro, M.D.18
Rotter, J.I.19
Schumm, L.P.20
Steinhart, A.H.21
Targan, S.R.22
Xavier, R.J.23
Libioulle, C.24
Sandor, C.25
Lathrop, M.26
Belaiche, J.27
Dewit, O.28
Gut, I.29
Heath, S.30
Laukens, D.31
Mni, M.32
Rutgeerts, P.33
Van Gossum, A.34
Zelenika, D.35
Franchimont, D.36
Hugot, J.P.37
De Vos, M.38
Vermeire, S.39
Louis, E.40
Cardon, L.R.41
Anderson, C.A.42
Drummond, H.43
Nimmo, E.44
Ahmad, T.45
Prescott, N.J.46
Onnie, C.M.47
Fisher, S.A.48
Marchini, J.49
Ghori, J.50
Bumpstead, S.51
Gwilliam, R.52
Tremelling, M.53
Deloukas, P.54
Mansfield, J.55
Jewell, D.56
Satsangi, J.57
Mathew, C.G.58
Parkes, M.59
Georges, M.60
Daly, M.J.61
more..
-
108
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
Yamazaki K, McGovern D, Ragoussis J, Paolucci M, Butler H, Jewell D, Cardon L, Takazoe M, Tanaka T, Ichimori T, Saito S, Sekine A, Iida A, Takahashi A, Tsunoda T, Lathrop M, Nakamura Y: Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet 2005; 14: 3499-3506.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
Jewell, D.6
Cardon, L.7
Takazoe, M.8
Tanaka, T.9
Ichimori, T.10
Saito, S.11
Sekine, A.12
Iida, A.13
Takahashi, A.14
Tsunoda, T.15
Lathrop, M.16
Nakamura, Y.17
-
109
-
-
33845340501
-
A genome-wide association study identifies IL-23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee AT, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH: A genome-wide association study identifies IL-23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
110
-
-
34247554965
-
Genomewide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR: Genomewide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
111
-
-
34247579326
-
Novel Crohn's disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M: Novel Crohn's disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007; 3:e58.
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
Sandor, C.4
Farnir, F.5
Franchimont, D.6
Vermeire, S.7
Dewit, O.8
De Vos, M.9
Dixon, A.10
Demarche, B.11
Gut, I.12
Heath, S.13
Foglio, M.14
Liang, L.15
Laukens, D.16
Mni, M.17
Zelenika, D.18
Van Gossum, A.19
Rutgeerts, P.20
Belaiche, J.21
Lathrop, M.22
Georges, M.23
more..
-
112
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Cardon L, Mathew CG: Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
Roberts, R.G.7
Nimmo, E.R.8
Cummings, F.R.9
Soars, D.10
Drummond, H.11
Lees, C.W.12
Khawaja, S.A.13
Bagnall, R.14
Burke, D.A.15
Todhunter, C.E.16
Ahmad, T.17
Onnie, C.M.18
McArdle, W.19
Strachan, D.20
Bethel, G.21
Bryan, C.22
Lewis, C.M.23
Deloukas, P.24
Forbes, A.25
Sanderson, J.26
Jewell, D.P.27
Satsangi, J.28
Mansfield, J.C.29
Cardon, L.30
Mathew, C.G.31
more..
-
113
-
-
55049111426
-
Sequence variants in IL-10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, Mathew CG, Schreiber S: Sequence variants in IL-10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 2008;40:1319-1323.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
Domingues, F.S.7
Albrecht, M.8
Nothnagel, M.9
Ellinghaus, D.10
Sina, C.11
Onnie, C.M.12
Weersma, R.K.13
Stokkers, P.C.14
Wijmenga, C.15
Gazouli, M.16
Strachan, D.17
McArdle, W.L.18
Vermeire, S.19
Rutgeerts, P.20
Rosenstiel, P.21
Krawczak, M.22
Vatn, M.H.23
Mathew, C.G.24
Schreiber, S.25
more..
-
114
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy MI, Abecasis GR, Cardon LR, Goldstein DB, Little J, Ioannidis JP, Hirschhorn JN: Genome-wide association studies for complex traits: consensus, uncertainty and challenges. Nat Rev Genet 2008; 9: 356-369.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
115
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, Collins FS, Manolio TA: Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009;106:9362-9367.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
116
-
-
35848970794
-
Genome-wide association scanning highlights two autophagy genes, Atg16L1 and IRGM, as being significantly associated with Crohn's disease
-
Massey DC, Parkes M: Genome-wide association scanning highlights two autophagy genes, Atg16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy 2007; 3: 649-651.
-
(2007)
Autophagy
, vol.3
, pp. 649-651
-
-
Massey, D.C.1
Parkes, M.2
-
117
-
-
34249997024
-
Replicating genotype-phenotype associations
-
Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni JF Jr, Freimer NB, Gerhard DS, Gunter C, Guttmacher AE, Guyer MS, Harris EL, Hoh J, Hoover R, Kong CA, Merikangas KR, Morton CC, Palmer LJ, Phimister EG, Rice JP, Roberts J, Rotimi C, Tucker MA, Vogan KJ, Wacholder S, Wijsman EM, Winn DM, Collins FS: Replicating genotype-phenotype associations. Nature 2007; 447: 655-660.
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
Boerwinkle, E.4
Hunter, D.J.5
Thomas, G.6
Hirschhorn, J.N.7
Abecasis, G.8
Altshuler, D.9
Bailey-Wilson, J.E.10
Brooks, L.D.11
Cardon, L.R.12
Daly, M.13
Donnelly, P.14
Fraumeni Jr., J.F.15
Freimer, N.B.16
Gerhard, D.S.17
Gunter, C.18
Guttmacher, A.E.19
Guyer, M.S.20
Harris, E.L.21
Hoh, J.22
Hoover, R.23
Kong, C.A.24
Merikangas, K.R.25
Morton, C.C.26
Palmer, L.J.27
Phimister, E.G.28
Rice, J.P.29
Roberts, J.30
Rotimi, C.31
Tucker, M.A.32
Vogan, K.J.33
Wacholder, S.34
Wijsman, E.M.35
Winn, D.M.36
Collins, F.S.37
more..
-
118
-
-
58149333555
-
Autoimmune diseases: Insights from genome-wide association studies
-
Lettre G, Rioux JD: Autoimmune diseases: Insights from genome-wide association studies. Hum Mol Genet 2008; 17:R116-R121.
-
(2008)
Hum Mol Genet
, vol.17
-
-
Lettre, G.1
Rioux, J.D.2
-
119
-
-
0036799545
-
The allelic architecture of human disease genes: Common disease- common variant ... or not?
-
Pritchard JK, Cox NJ: The allelic architecture of human disease genes: common disease- common variant ... or not? Hum Mol Genet 2002; 11: 2417-2423.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2417-2423
-
-
Pritchard, J.K.1
Cox, N.J.2
-
120
-
-
40949112379
-
The Atg16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
-
Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Torok HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Goke B, Ochsenkuhn T, Mussack T, Folwaczny M, Muller-Myhsok B, Brand S: The Atg16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2008; 103: 682-691.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 682-691
-
-
Glas, J.1
Konrad, A.2
Schmechel, S.3
Dambacher, J.4
Seiderer, J.5
Schroff, F.6
Wetzke, M.7
Roeske, D.8
Torok, H.P.9
Tonenchi, L.10
Pfennig, S.11
Haller, D.12
Griga, T.13
Klein, W.14
Epplen, J.T.15
Folwaczny, C.16
Lohse, P.17
Goke, B.18
Ochsenkuhn, T.19
Mussack, T.20
Folwaczny, M.21
Muller-Myhsok, B.22
Brand, S.23
more..
-
121
-
-
58149201215
-
Replication of interleukin-23 receptor and autophagyrelated 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy
-
Latiano A, Palmieri O, Valvano MR, D'Inca R, Cucchiara S, Riegler G, Staiano AM, Ardizzone S, Accomando S, de Angelis GL, Corritore G, Bossa F, Annese V: Replication of interleukin-23 receptor and autophagyrelated 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy. World J Gastroenterol 2008; 14: 4643-4651.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 4643-4651
-
-
Latiano, A.1
Palmieri, O.2
Valvano, M.R.3
D'Inca, R.4
Cucchiara, S.5
Riegler, G.6
Staiano, A.M.7
Ardizzone, S.8
Accomando, S.9
De Angelis, G.L.10
Corritore, G.11
Bossa, F.12
Annese, V.13
-
122
-
-
41149137717
-
Autophagy gene Atg16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe
-
Van Limbergen J, Russell RK, Nimmo ER, Drummond HE, Smith L, Anderson NH, Davies G, Gillett PM, McGrogan P, Weaver LT, Bisset WM, Mahdi G, Arnott ID, Wilson DC, Satsangi J: Autophagy gene Atg16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe. Inflamm Bowel Dis 2008; 14: 338-346.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 338-346
-
-
Van Limbergen, J.1
Russell, R.K.2
Nimmo, E.R.3
Drummond, H.E.4
Smith, L.5
Anderson, N.H.6
Davies, G.7
Gillett, P.M.8
McGrogan, P.9
Weaver, L.T.10
Bisset, W.M.11
Mahdi, G.12
Arnott, I.D.13
Wilson, D.C.14
Satsangi, J.15
-
123
-
-
34247566585
-
A nonsynonymous SNP in ATG16I1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie CM, Soars D, Bagnall R, Mirza MM, Sanderson J, Forbes A, Mansfield JC, Lewis CM, Schreiber S, Mathew CG:
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
Hampe, J.4
Onnie, C.M.5
Soars, D.6
Bagnall, R.7
Mirza, M.M.8
Sanderson, J.9
Forbes, A.10
Mansfield, J.C.11
Lewis, C.M.12
Schreiber, S.13
Mathew, C.G.14
-
124
-
-
40949105649
-
Atg16L1 and IL-23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands
-
Weersma RK, Zhernakova A, Nolte IM, Lefebvre C, Rioux JD, Mulder F, van Dullemen HM, Kleibeuker JH, Wijmenga C, Dijkstra G: Atg16L1 and IL-23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands. Am J Gastroenterol 2008; 103: 621-627.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 621-627
-
-
Weersma, R.K.1
Zhernakova, A.2
Nolte, I.M.3
Lefebvre, C.4
Rioux, J.D.5
Mulder, F.6
Van Dullemen, H.M.7
Kleibeuker, J.H.8
Wijmenga, C.9
Dijkstra, G.10
-
125
-
-
51249103405
-
Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population- based cohort
-
Roberts RL, Hollis-Moffatt JE, Gearry RB, Kennedy MA, Barclay ML, Merriman TR: Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population- based cohort. Genes Immun 2008; 9: 561-565.
-
(2008)
Genes Immun
, vol.9
, pp. 561-565
-
-
Roberts, R.L.1
Hollis-Moffatt, J.E.2
Gearry, R.B.3
Kennedy, M.A.4
Barclay, M.L.5
Merriman, T.R.6
-
126
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher SA, Tremelling M, Anderson CA, Gwilliam R, Bumpstead S, Prescott NJ, Nimmo ER, Massey D, Berzuini C, Johnson C, Barrett JC, Cummings FR, Drummond H, Lees CW, Onnie CM, Hanson CE, Blaszczyk K, Inouye M, Ewels P, Ravindrarajah R, Keniry A, Hunt S, Carter M, Watkins N, Ouwehand W, Lewis CM, Cardon L, Lobo A, Forbes A, Sanderson J, Jewell DP, Mansfield JC, Deloukas P, Mathew CG, Parkes M, Satsangi J: Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet 2008; 40: 710-712.
-
(2008)
Nat Genet
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
Tremelling, M.2
Anderson, C.A.3
Gwilliam, R.4
Bumpstead, S.5
Prescott, N.J.6
Nimmo, E.R.7
Massey, D.8
Berzuini, C.9
Johnson, C.10
Barrett, J.C.11
Cummings, F.R.12
Drummond, H.13
Lees, C.W.14
Onnie, C.M.15
Hanson, C.E.16
Blaszczyk, K.17
Inouye, M.18
Ewels, P.19
Ravindrarajah, R.20
Keniry, A.21
Hunt, S.22
Carter, M.23
Watkins, N.24
Ouwehand, W.25
Lewis, C.M.26
Cardon, L.27
Lobo, A.28
Forbes, A.29
Sanderson, J.30
Jewell, D.P.31
Mansfield, J.C.32
Deloukas, P.33
Mathew, C.G.34
Parkes, M.35
Satsangi, J.36
more..
-
127
-
-
34248203863
-
Structure of Atg5.Atg16, a complex essential for autophagy
-
Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F: Structure of Atg5.Atg16, a complex essential for autophagy. J Biol Chem 2007; 282: 6763-6772.
-
(2007)
J Biol Chem
, vol.282
, pp. 6763-6772
-
-
Matsushita, M.1
Suzuki, N.N.2
Obara, K.3
Fujioka, Y.4
Ohsumi, Y.5
Inagaki, F.6
-
128
-
-
0029664589
-
The 2.0 Å crystal structure of a heterotrimeric g protein
-
Lambright DG, Sondek J, Bohm A, Skiba NP, Hamm HE, Sigler PB: The 2.0 Å crystal structure of a heterotrimeric g protein. Nature 1996; 379: 311-319.
-
(1996)
Nature
, vol.379
, pp. 311-319
-
-
Lambright, D.G.1
Sondek, J.2
Bohm, A.3
Skiba, N.P.4
Hamm, H.E.5
Sigler, P.B.6
-
130
-
-
0037166241
-
Formation of the approximately 350- kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast
-
Kuma A, Mizushima N, Ishihara N, Ohsumi Y: Formation of the approximately 350- kDa Apg12-Apg5.Apg16 multimeric complex, mediated by Apg16 oligomerization, is essential for autophagy in yeast. J Biol Chem 2002; 277: 18619-18625.
-
(2002)
J Biol Chem
, vol.277
, pp. 18619-18625
-
-
Kuma, A.1
Mizushima, N.2
Ishihara, N.3
Ohsumi, Y.4
-
131
-
-
42449126123
-
Crystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free-interface diffusion method
-
Noda NN, Fujioka Y, Ohsumi Y, Inagaki F: Crystallization of the Atg12-Atg5 conjugate bound to Atg16 by the free-interface diffusion method. J Synchrotron Radiat 2008; 15: 266-268.
-
(2008)
J Synchrotron Radiat
, vol.15
, pp. 266-268
-
-
Noda, N.N.1
Fujioka, Y.2
Ohsumi, Y.3
Inagaki, F.4
-
132
-
-
33749507373
-
Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy
-
Matsushita M, Suzuki NN, Fujioka Y, Ohsumi Y, Inagaki F: Expression, purification and crystallization of the Atg5-Atg16 complex essential for autophagy. Acta Crystallograph Sect F Struct Biol Cryst Commun 2006; 62: 1021-1023.
-
(2006)
Acta Crystallograph Sect F Struct Biol Cryst Commun
, vol.62
, pp. 1021-1023
-
-
Matsushita, M.1
Suzuki, N.N.2
Fujioka, Y.3
Ohsumi, Y.4
Inagaki, F.5
-
133
-
-
33745088813
-
Structure-function relationship of ATG12, a ubiquitin-like modifier essential for autophagy
-
Hanada T, Ohsumi Y: Structure-function relationship of ATG12, a ubiquitin-like modifier essential for autophagy. Autophagy 2005; 1: 110-118.
-
(2005)
Autophagy
, vol.1
, pp. 110-118
-
-
Hanada, T.1
Ohsumi, Y.2
-
134
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T: The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 2008; 19: 2092-2100.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
135
-
-
50249131810
-
Direct link between ATG protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals
-
Fukuda M, Itoh T: Direct link between ATG protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals. Autophagy 2008; 4: 824-826.
-
(2008)
Autophagy
, vol.4
, pp. 824-826
-
-
Fukuda, M.1
Itoh, T.2
-
136
-
-
50249098491
-
Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation
-
Itoh T, Fujita N, Kanno E, Yamamoto A, Yoshimori T, Fukuda M: Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell 2008; 19: 2916-2925.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2916-2925
-
-
Itoh, T.1
Fujita, N.2
Kanno, E.3
Yamamoto, A.4
Yoshimori, T.5
Fukuda, M.6
-
137
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL- 1- production
-
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S: Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL- 1- production. Nature 2008; 456: 264-268.
-
(2008)
Nature
, vol.456
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
Uematsu, S.4
Yang, B.G.5
Satoh, T.6
Omori, H.7
Noda, T.8
Yamamoto, N.9
Komatsu, M.10
Tanaka, K.11
Kawai, T.12
Tsujimura, T.13
Takeuchi, O.14
Yoshimori, T.15
Akira, S.16
-
138
-
-
56249135538
-
Virgin HW 4th: A key role for autophagy and the autophagy gene Atg16L1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin HW 4th: A key role for autophagy and the autophagy gene Atg16L1 in mouse and human intestinal Paneth cells. Nature 2008; 456: 259-263.
-
(2008)
Nature
, vol.456
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
Miyoshi, H.4
Loh, J.5
Lennerz, J.K.6
Kishi, C.7
Kc, W.8
Carrero, J.A.9
Hunt, S.10
Stone, C.D.11
Brunt, E.M.12
Xavier, R.J.13
Sleckman, B.P.14
Li, E.15
Mizushima, N.16
Stappenbeck, T.S.17
-
139
-
-
55549114327
-
Autophagy gives a nod and a wink to the inflammasome and Paneth cells in Crohn's disease
-
Deretic V, Master S, Singh S: Autophagy gives a nod and a wink to the inflammasome and Paneth cells in Crohn's disease. Dev Cell 2008; 15: 641-642.
-
(2008)
Dev Cell
, vol.15
, pp. 641-642
-
-
Deretic, V.1
Master, S.2
Singh, S.3
-
140
-
-
21144434528
-
Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease
-
Yamamoto K, Kiyohara T, Murayama Y, Kihara S, Okamoto Y, Funahashi T, Ito T, Nezu R, Tsutsui S, Miyagawa JI, Tamura S, Matsuzawa Y, Shimomura I, Shinomura Y: Production of adiponectin, an anti-inflammatory protein, in mesenteric adipose tissue in Crohn's disease. Gut 2005; 54: 789-796.
-
(2005)
Gut
, vol.54
, pp. 789-796
-
-
Yamamoto, K.1
Kiyohara, T.2
Murayama, Y.3
Kihara, S.4
Okamoto, Y.5
Funahashi, T.6
Ito, T.7
Nezu, R.8
Tsutsui, S.9
Miyagawa, J.I.10
Tamura, S.11
Matsuzawa, Y.12
Shimomura, I.13
Shinomura, Y.14
-
141
-
-
0019060557
-
Crohn's disease: Transmission electron microscopic studies. I. Barrier function. Possible changes related to alterations of cell coat, mucous coat, epithelial cells, and Paneth cells
-
Dvorak AM, Dickersin GR: Crohn's disease: transmission electron microscopic studies. I. Barrier function. Possible changes related to alterations of cell coat, mucous coat, epithelial cells, and Paneth cells. Hum Pathol 1980; 11: 561-571.
-
(1980)
Hum Pathol
, vol.11
, pp. 561-571
-
-
Dvorak, A.M.1
Dickersin, G.R.2
-
142
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll SA, Huett A, Kuballa P, Chilewski SD, Landry A, Goyette P, Zody MC, Hall JL, Brant SR, Cho JH, Duerr RH, Silverberg MS, Taylor KD, Rioux JD, Altshuler D, Daly MJ, Xavier RJ: Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet 2008; 40: 1107-1112.
-
(2008)
Nat Genet
, vol.40
, pp. 1107-1112
-
-
McCarroll, S.A.1
Huett, A.2
Kuballa, P.3
Chilewski, S.D.4
Landry, A.5
Goyette, P.6
Zody, M.C.7
Hall, J.L.8
Brant, S.R.9
Cho, J.H.10
Duerr, R.H.11
Silverberg, M.S.12
Taylor, K.D.13
Rioux, J.D.14
Altshuler, D.15
Daly, M.J.16
Xavier, R.J.17
-
143
-
-
0035898464
-
Inactivation of LRG-47 and IRG-47 reveals a family of interferon- -inducible genes with essential, pathogen-specific roles in resistance to infection
-
Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, Woude GF, Sher A, Taylor GA: Inactivation of LRG-47 and IRG-47 reveals a family of interferon- -inducible genes with essential, pathogen-specific roles in resistance to infection. J Exp Med 2001; 194: 181-188.
-
(2001)
J Exp Med
, vol.194
, pp. 181-188
-
-
Collazo, C.M.1
Yap, G.S.2
Sempowski, G.D.3
Lusby, K.C.4
Tessarollo, L.5
Woude, G.F.6
Sher, A.7
Taylor, G.A.8
-
144
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
Singh SB, Davis AS, Taylor GA, Deretic V: Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science 2006; 313: 1438-1441.
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
145
-
-
0038325675
-
Mouse APG16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate
-
Mizushima N, Kuma A, Kobayashi Y, Yamamoto A, Matsubae M, Takao T, Natsume T, Ohsumi Y, Yoshimori T: Mouse APG16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate. J Cell Sci 2003; 116: 1679-1688.
-
(2003)
J Cell Sci
, vol.116
, pp. 1679-1688
-
-
Mizushima, N.1
Kuma, A.2
Kobayashi, Y.3
Yamamoto, A.4
Matsubae, M.5
Takao, T.6
Natsume, T.7
Ohsumi, Y.8
Yoshimori, T.9
-
146
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated Atg16L1 variant
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ: Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated Atg16L1 variant. PLoS One 2008; 3:e3391.
-
(2008)
PLoS One
, vol.3
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
147
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T-cell activation state characterized by the production of interleukin- 17
-
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL: Interleukin-23 promotes a distinct CD4 T-cell activation state characterized by the production of interleukin- 17. J Biol Chem 2003; 278: 1910-1914.
-
(2003)
J Biol Chem
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
148
-
-
27544490377
-
Interleukin-17-producing CD4+ effector T cells develop via a lineage distinct from the T-helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, Weaver CT: Interleukin-17-producing CD4+ effector T cells develop via a lineage distinct from the T-helper type 1 and 2 lineages. Nat Immunol 2005; 6: 1123-1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
149
-
-
32244442562
-
TGF-- in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B: TGF-- in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006; 24: 179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
150
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
Kolls JK, Linden A: Interleukin-17 family members and inflammation. Immunity 2004; 21: 467-476.
-
(2004)
Immunity
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Linden, A.2
-
151
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
DOI 10.1136/gut.52.1.65
-
Fujino S, Andoh A, Bamba S, Ogawa A, Hata K, Araki Y, Bamba T, Fujiyama Y: Increased expression of interleukin-17 in inflammatory bowel disease. Gut 2003; 52: 65-70. (Pubitemid 36020767)
-
(2003)
Gut
, vol.52
, Issue.1
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
Ogawa, A.4
Hata, K.5
Araki, Y.6
Bamba, T.7
Fujiyama, Y.8
-
152
-
-
33646397611
-
IL-23 is essential for T cellmediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D: IL-23 is essential for T cellmediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006; 116: 1310-1316.
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
Murphy, E.11
Sathe, M.12
Cua, D.J.13
Kastelein, R.A.14
Rennick, D.15
-
153
-
-
34948840330
-
The IL-23 axis plays a key role in the pathogenesis of IBD
-
McGovern D, Powrie F: The IL-23 axis plays a key role in the pathogenesis of IBD. Gut 2007; 56: 1333-1336.
-
(2007)
Gut
, vol.56
, pp. 1333-1336
-
-
McGovern, D.1
Powrie, F.2
-
154
-
-
8344284998
-
Anti-interleukin- 12 antibody for active Crohn's disease
-
Mannon PJ, Fuss IJ, Mayer L, Elson CO, Sandborn WJ, Present D, Dolin B, Goodman N, Groden C, Hornung RL, Quezado M, Yang Z, Neurath MF, Salfeld J, Veldman GM, Schwertschlag U, Strober W: Anti-interleukin- 12 antibody for active Crohn's disease. N Engl J Med 2004; 351: 2069-2079.
-
(2004)
N Engl J Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
Elson, C.O.4
Sandborn, W.J.5
Present, D.6
Dolin, B.7
Goodman, N.8
Groden, C.9
Hornung, R.L.10
Quezado, M.11
Yang, Z.12
Neurath, M.F.13
Salfeld, J.14
Veldman, G.M.15
Schwertschlag, U.16
Strober, W.17
-
155
-
-
53049091561
-
A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN, Scherl E, Fleisher MR, Katz S, Johanns J, Blank M, Rutgeerts P: A randomized trial of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 2008; 135: 1130-1141.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
Scherl, E.4
Fleisher, M.R.5
Katz, S.6
Johanns, J.7
Blank, M.8
Rutgeerts, P.9
-
156
-
-
0035877257
-
Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death
-
Wiekowski MT, Leach MW, Evans EW, Sullivan L, Chen SC, Vassileva G, Bazan JF, Gorman DM, Kastelein RA, Narula S, Lira SA: Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death. J Immunol 2001; 166: 7563-7570.
-
(2001)
J Immunol
, vol.166
, pp. 7563-7570
-
-
Wiekowski, M.T.1
Leach, M.W.2
Evans, E.W.3
Sullivan, L.4
Chen, S.C.5
Vassileva, G.6
Bazan, J.F.7
Gorman, D.M.8
Kastelein, R.A.9
Narula, S.10
Lira, S.A.11
-
157
-
-
55049111426
-
Sequence variants in IL-10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, Mathew CG, Schreiber S: Sequence variants in IL-10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet 2008; 40: 1319-1323.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Sventoraityte, J.4
Nikolaus, S.5
Mayr, G.6
Domingues, F.S.7
Albrecht, M.8
Nothnagel, M.9
Ellinghaus, D.10
Sina, C.11
Onnie, C.M.12
Weersma, R.K.13
Stokkers, P.C.14
Wijmenga, C.15
Gazouli, M.16
Strachan, D.17
McArdle, W.L.18
Vermeire, S.19
Rutgeerts, P.20
Rosenstiel, P.21
Krawczak, M.22
Vatn, M.H.23
Mathew, C.G.24
Schreiber, S.25
more..
-
158
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, Schuldt D, Nikolaus S, Rosenstiel P, Krawczak M, Schreiber S: Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 2008; 40: 713-715.
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
Hedderich, J.4
May, S.5
Lu, T.6
Schuldt, D.7
Nikolaus, S.8
Rosenstiel, P.9
Krawczak, M.10
Schreiber, S.11
-
159
-
-
44349127803
-
New susceptibility genes for ulcerative colitis
-
Dubois PC, van Heel DA: New susceptibility genes for ulcerative colitis. Nat Genet 2008; 40: 686-688.
-
(2008)
Nat Genet
, vol.40
, pp. 686-688
-
-
Dubois, P.C.1
Van Heel, D.A.2
-
160
-
-
58949097704
-
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
-
Anderson CA, Massey DC, Barrett JC, Prescott NJ, Tremelling M, Fisher SA, Gwilliam R, Jacob J, Nimmo ER, Drummond H, Lees CW, Onnie CM, Hanson C, Blaszczyk K, Ravindrarajah R, Hunt S, Varma D, Hammond N, Lewis G, Attlesey H, Watkins N, Ouwehand W, Strachan D, McArdle W, Lewis CM, Lobo A, Sanderson J, Jewell DP, Deloukas P, Mansfield JC, Mathew CG, Satsangi J, Parkes M: Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 2009; 136: 523-529.
-
(2009)
Gastroenterology
, vol.136
, pp. 523-529
-
-
Anderson, C.A.1
Massey, D.C.2
Barrett, J.C.3
Prescott, N.J.4
Tremelling, M.5
Fisher, S.A.6
Gwilliam, R.7
Jacob, J.8
Nimmo, E.R.9
Drummond, H.10
Lees, C.W.11
Onnie, C.M.12
Hanson, C.13
Blaszczyk, K.14
Ravindrarajah, R.15
Hunt, S.16
Varma, D.17
Hammond, N.18
Lewis, G.19
Attlesey, H.20
Watkins, N.21
Ouwehand, W.22
Strachan, D.23
McArdle, W.24
Lewis, C.M.25
Lobo, A.26
Sanderson, J.27
Jewell, D.P.28
Deloukas, P.29
Mansfield, J.C.30
Mathew, C.G.31
Satsangi, J.32
Parkes, M.33
more..
-
161
-
-
55249099547
-
Ulcerative colitis and Crohn's disease genetics: More similar than we thought?
-
Sans M, Castells A: Ulcerative colitis and Crohn's disease genetics: more similar than we thought? Gastroenterology 2008; 135: 1796-1798.
-
(2008)
Gastroenterology
, vol.135
, pp. 1796-1798
-
-
Sans, M.1
Castells, A.2
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