-
1
-
-
0037043658
-
Inflammatory bowel disease
-
Podolsky DK. Inflammatory bowel disease. N Engl J Med 2002; 347: 417-429
-
(2002)
N Engl J Med
, vol.347
, pp. 417-429
-
-
Podolsky, D.K.1
-
2
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007; 448: 427-434
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
3
-
-
11144354272
-
Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs
-
van Heel DA, Fisher SA, Kirby A, Daly MJ, Rioux JD, Lewis CM. Inflammatory bowel disease susceptibility loci defined by genome scan meta-analysis of 1952 affected relative pairs. Hum Mol Genet 2004; 13: 763-770
-
(2004)
Hum Mol Genet
, vol.13
, pp. 763-770
-
-
van Heel, D.A.1
Fisher, S.A.2
Kirby, A.3
Daly, M.J.4
Rioux, J.D.5
Lewis, C.M.6
-
4
-
-
0036875821
-
Using a genome-wide scan and meta-analysis to identify a novel IBD locus and confirm previously identified IBD loci
-
Williams CN, Kocher K, Lander ES, Daly MJ, Rioux JD. Using a genome-wide scan and meta-analysis to identify a novel IBD locus and confirm previously identified IBD loci. Inflamm Bowel Dis 2002; 8: 375-381
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 375-381
-
-
Williams, C.N.1
Kocher, K.2
Lander, E.S.3
Daly, M.J.4
Rioux, J.D.5
-
6
-
-
0034785352
-
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
-
Rioux JD, Daly MJ, Silverberg MS, Lindblad K, Steinhart H, Cohen Z, Delmonte T, Kocher K, Miller K, Guschwan S, Kulbokas EJ, O'Leary S, Winchester E, Dewar K, Green T, Stone V, Chow C, Cohen A, Langelier D, Lapointe G, Gaudet D, Faith J, Branco N, Bull SB, McLeod RS, Griffiths AM, Bitton A, Greenberg GR, Lander ES, Siminovitch KA, Hudson TJ. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease. Nat Genet 2001; 29: 223-228
-
(2001)
Nat Genet
, vol.29
, pp. 223-228
-
-
Rioux, J.D.1
Daly, M.J.2
Silverberg, M.S.3
Lindblad, K.4
Steinhart, H.5
Cohen, Z.6
Delmonte, T.7
Kocher, K.8
Miller, K.9
Guschwan, S.10
Kulbokas, E.J.11
O'Leary, S.12
Winchester, E.13
Dewar, K.14
Green, T.15
Stone, V.16
Chow, C.17
Cohen, A.18
Langelier, D.19
Lapointe, G.20
Gaudet, D.21
Faith, J.22
Branco, N.23
Bull, S.B.24
McLeod, R.S.25
Griffiths, A.M.26
Bitton, A.27
Greenberg, G.R.28
Lander, E.S.29
Siminovitch, K.A.30
Hudson, T.J.31
more..
-
7
-
-
2442585704
-
Functional variants of OCTN cation transporter genes are associated with Crohn disease
-
Peltekova VD, Wintle RF, Rubin LA, Amos CI, Huang Q, Gu X, Newman B, Van Oene M, Cescon D, Greenberg G, Griffiths AM, St George-Hyslop PH, Siminovitch KA. Functional variants of OCTN cation transporter genes are associated with Crohn disease. Nat Genet 2004; 36: 471-475
-
(2004)
Nat Genet
, vol.36
, pp. 471-475
-
-
Peltekova, V.D.1
Wintle, R.F.2
Rubin, L.A.3
Amos, C.I.4
Huang, Q.5
Gu, X.6
Newman, B.7
Van Oene, M.8
Cescon, D.9
Greenberg, G.10
Griffiths, A.M.11
St George-Hyslop, P.H.12
Siminovitch, K.A.13
-
8
-
-
2442519456
-
Genetic variation in DLG5 is associated with inflammatory bowel disease
-
Stoll M, Corneliussen B, Costello CM, Waetzig GH, Mellgard B, Koch WA, Rosenstiel P, Albrecht M, Croucher PJ, Seegert D, Nikolaus S, Hampe J, Lengauer T, Pierrou S, Foelsch UR, Mathew CG, Lagerstrom-Fermer M, Schreiber S. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat Genet 2004; 36: 476-480
-
(2004)
Nat Genet
, vol.36
, pp. 476-480
-
-
Stoll, M.1
Corneliussen, B.2
Costello, C.M.3
Waetzig, G.H.4
Mellgard, B.5
Koch, W.A.6
Rosenstiel, P.7
Albrecht, M.8
Croucher, P.J.9
Seegert, D.10
Nikolaus, S.11
Hampe, J.12
Lengauer, T.13
Pierrou, S.14
Foelsch, U.R.15
Mathew, C.G.16
Lagerstrom-Fermer, M.17
Schreiber, S.18
-
9
-
-
33144478521
-
ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: Discrimination of critical variants using a gene-wide haplotype tagging approach
-
Ho GT, Soranzo N, Nimmo ER, Tenesa A, Goldstein DB, Satsangi J. ABCB1/MDR1 gene determines susceptibility and phenotype in ulcerative colitis: discrimination of critical variants using a gene-wide haplotype tagging approach. Hum Mol Genet 2006; 15: 797-805
-
(2006)
Hum Mol Genet
, vol.15
, pp. 797-805
-
-
Ho, G.T.1
Soranzo, N.2
Nimmo, E.R.3
Tenesa, A.4
Goldstein, D.B.5
Satsangi, J.6
-
10
-
-
3042521641
-
Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis
-
Franchimont D, Vermeire S, El Housni H, Pierik M, Van Steen K, Gustot T, Quertinmont E, Abramowicz M, Van Gossum A, Deviere J, Rutgeerts P. Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut 2004; 53: 987-992
-
(2004)
Gut
, vol.53
, pp. 987-992
-
-
Franchimont, D.1
Vermeire, S.2
El Housni, H.3
Pierik, M.4
Van Steen, K.5
Gustot, T.6
Quertinmont, E.7
Abramowicz, M.8
Van Gossum, A.9
Deviere, J.10
Rutgeerts, P.11
-
11
-
-
27944464550
-
Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease
-
Yamazaki K, McGovern D, Ragoussis J, Paolucci M, Butler H, Jewell D, Cardon L, Takazoe M, Tanaka T, Ichimori T, Saito S, Sekine A, Iida A, Takahashi A, Tsunoda T, Lathrop M, Nakamura Y. Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet 2005; 14: 3499-3506
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3499-3506
-
-
Yamazaki, K.1
McGovern, D.2
Ragoussis, J.3
Paolucci, M.4
Butler, H.5
Jewell, D.6
Cardon, L.7
Takazoe, M.8
Tanaka, T.9
Ichimori, T.10
Saito, S.11
Sekine, A.12
Iida, A.13
Takahashi, A.14
Tsunoda, T.15
Lathrop, M.16
Nakamura, Y.17
-
12
-
-
33845622964
-
Genetic variation in myosin IXB is associated with ulcerative colitis
-
van Bodegraven AA, Curley CR, Hunt KA, Monsuur AJ, Linskens RK, Onnie CM, Crusius JB, Annese V, Latiano A, Silverberg MS, Bitton A, Fisher SA, Steinhart AH, Forbes A, Sanderson J, Prescott NJ, Strachan DP, Playford RJ, Mathew CG, Wijmenga C, Daly MJ, Rioux JD, van Heel DA. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 2006; 131: 1768-1774
-
(2006)
Gastroenterology
, vol.131
, pp. 1768-1774
-
-
van Bodegraven, A.A.1
Curley, C.R.2
Hunt, K.A.3
Monsuur, A.J.4
Linskens, R.K.5
Onnie, C.M.6
Crusius, J.B.7
Annese, V.8
Latiano, A.9
Silverberg, M.S.10
Bitton, A.11
Fisher, S.A.12
Steinhart, A.H.13
Forbes, A.14
Sanderson, J.15
Prescott, N.J.16
Strachan, D.P.17
Playford, R.J.18
Mathew, C.G.19
Wijmenga, C.20
Daly, M.J.21
Rioux, J.D.22
van Heel, D.A.23
more..
-
13
-
-
33749465291
-
TUCAN (CARD8) genetic variants and inflammatory bowel disease
-
McGovern DP, Butler H, Ahmad T, Paolucci M, van Heel DA, Negoro K, Hysi P, Ragoussis J, Travis SP, Cardon LR, Jewell DP. TUCAN (CARD8) genetic variants and inflammatory bowel disease. Gastroenterology 2006; 131: 1190-1196
-
(2006)
Gastroenterology
, vol.131
, pp. 1190-1196
-
-
McGovern, D.P.1
Butler, H.2
Ahmad, T.3
Paolucci, M.4
van Heel, D.A.5
Negoro, K.6
Hysi, P.7
Ragoussis, J.8
Travis, S.P.9
Cardon, L.R.10
Jewell, D.P.11
-
14
-
-
34848850085
-
The genetics of inflammatory bowel disease
-
Cho JH, Weaver CT. The genetics of inflammatory bowel disease. Gastroenterology 2007; 133: 1327-1339
-
(2007)
Gastroenterology
, vol.133
, pp. 1327-1339
-
-
Cho, J.H.1
Weaver, C.T.2
-
15
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M, Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW, Kistner EO, Schumm LP, Lee AT, Gregersen PK, Barmada MM, Rotter JI, Nicolae DL, Cho JH. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006; 314: 1461-1463
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
Rioux, J.D.4
Silverberg, M.S.5
Daly, M.J.6
Steinhart, A.H.7
Abraham, C.8
Regueiro, M.9
Griffiths, A.10
Dassopoulos, T.11
Bitton, A.12
Yang, H.13
Targan, S.14
Datta, L.W.15
Kistner, E.O.16
Schumm, L.P.17
Lee, A.T.18
Gregersen, P.K.19
Barmada, M.M.20
Rotter, J.I.21
Nicolae, D.L.22
Cho, J.H.23
more..
-
16
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007; 39: 596-604
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
Silverberg, M.S.4
Goyette, P.5
Huett, A.6
Green, T.7
Kuballa, P.8
Barmada, M.M.9
Datta, L.W.10
Shugart, Y.Y.11
Griffiths, A.M.12
Targan, S.R.13
Ippoliti, A.F.14
Bernard, E.J.15
Mei, L.16
Nicolae, D.L.17
Regueiro, M.18
Schumm, L.P.19
Steinhart, A.H.20
Rotter, J.I.21
Duerr, R.H.22
Cho, J.H.23
Daly, M.J.24
Brant, S.R.25
more..
-
17
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007; 447: 661-678
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
18
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, Sandor C, Farnir F, Franchimont D, Vermeire S, Dewit O, de Vos M, Dixon A, Demarche B, Gut I, Heath S, Foglio M, Liang L, Laukens D, Mni M, Zelenika D, Van Gossum A, Rutgeerts P, Belaiche J, Lathrop M, Georges M. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007; 3: e58
-
(2007)
PLoS Genet
, vol.3
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
Sandor, C.4
Farnir, F.5
Franchimont, D.6
Vermeire, S.7
Dewit, O.8
de Vos, M.9
Dixon, A.10
Demarche, B.11
Gut, I.12
Heath, S.13
Foglio, M.14
Liang, L.15
Laukens, D.16
Mni, M.17
Zelenika, D.18
Van Gossum, A.19
Rutgeerts, P.20
Belaiche, J.21
Lathrop, M.22
Georges, M.23
more..
-
19
-
-
37249034766
-
Systematic association mapping identifies NELL1 as a novel IBD disease gene
-
Franke A, Hampe J, Rosenstiel P, Becker C, Wagner F, Hasler R, Little RD, Huse K, Ruether A, Balschun T, Wittig M, Elsharawy A, Mayr G, Albrecht M, Prescott NJ, Onnie CM, Fournier H, Keith T, Radelof U, Platzer M, Mathew CG, Stoll M, Krawczak M, Nurnberg P, Schreiber S. Systematic association mapping identifies NELL1 as a novel IBD disease gene. PLoS ONE 2007; 2: e691
-
(2007)
PLoS ONE
, vol.2
-
-
Franke, A.1
Hampe, J.2
Rosenstiel, P.3
Becker, C.4
Wagner, F.5
Hasler, R.6
Little, R.D.7
Huse, K.8
Ruether, A.9
Balschun, T.10
Wittig, M.11
Elsharawy, A.12
Mayr, G.13
Albrecht, M.14
Prescott, N.J.15
Onnie, C.M.16
Fournier, H.17
Keith, T.18
Radelof, U.19
Platzer, M.20
Mathew, C.G.21
Stoll, M.22
Krawczak, M.23
Nurnberg, P.24
Schreiber, S.25
more..
-
20
-
-
34548527714
-
Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype
-
Cummings JR, Ahmad T, Geremia A, Beckly J, Cooney R, Hancock L, Pathan S, Guo C, Cardon LR, Jewell DP. Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype. Inflamm Bowel Dis 2007; 13: 1063-1068
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 1063-1068
-
-
Cummings, J.R.1
Ahmad, T.2
Geremia, A.3
Beckly, J.4
Cooney, R.5
Hancock, L.6
Pathan, S.7
Guo, C.8
Cardon, L.R.9
Jewell, D.P.10
-
21
-
-
34347338690
-
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Cardon L, Mathew CG. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832
-
Parkes M, Barrett JC, Prescott NJ, Tremelling M, Anderson CA, Fisher SA, Roberts RG, Nimmo ER, Cummings FR, Soars D, Drummond H, Lees CW, Khawaja SA, Bagnall R, Burke DA, Todhunter CE, Ahmad T, Onnie CM, McArdle W, Strachan D, Bethel G, Bryan C, Lewis CM, Deloukas P, Forbes A, Sanderson J, Jewell DP, Satsangi J, Mansfield JC, Cardon L, Mathew CG. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007; 39: 830-832
-
-
-
-
22
-
-
34247560627
-
IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease
-
Tremelling M, Cummings F, Fisher SA, Mansfield J, Gwilliam R, Keniry A, Nimmo ER, Drummond H, Onnie CM, Prescott NJ, Sanderson J, Bredin F, Berzuini C, Forbes A, Lewis CM, Cardon L, Deloukas P, Jewell D, Mathew CG, Parkes M, Satsangi J. IL23R variation determines susceptibility but not disease phenotype in inflammatory bowel disease. Gastroenterology 2007; 132: 1657-1664
-
(2007)
Gastroenterology
, vol.132
, pp. 1657-1664
-
-
Tremelling, M.1
Cummings, F.2
Fisher, S.A.3
Mansfield, J.4
Gwilliam, R.5
Keniry, A.6
Nimmo, E.R.7
Drummond, H.8
Onnie, C.M.9
Prescott, N.J.10
Sanderson, J.11
Bredin, F.12
Berzuini, C.13
Forbes, A.14
Lewis, C.M.15
Cardon, L.16
Deloukas, P.17
Jewell, D.18
Mathew, C.G.19
Parkes, M.20
Satsangi, J.21
more..
-
23
-
-
39649106413
-
rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: Combined analysis of IL23R, CARD15, and OCTN1/2 variants
-
Glas J, Seiderer J, Wetzke M, Konrad A, Torok HP, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Maier K, Griga T, Klein W, Epplen JT, Schiemann U, Folwaczny C, Lohse P, Goke B, Ochsenkuhn T, Muller-Myhsok B, Folwaczny M, Mussack T, Brand S. rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PLoS ONE 2007; 2: e819
-
(2007)
PLoS ONE
, vol.2
-
-
Glas, J.1
Seiderer, J.2
Wetzke, M.3
Konrad, A.4
Torok, H.P.5
Schmechel, S.6
Tonenchi, L.7
Grassl, C.8
Dambacher, J.9
Pfennig, S.10
Maier, K.11
Griga, T.12
Klein, W.13
Epplen, J.T.14
Schiemann, U.15
Folwaczny, C.16
Lohse, P.17
Goke, B.18
Ochsenkuhn, T.19
Muller-Myhsok, B.20
Folwaczny, M.21
Mussack, T.22
Brand, S.23
more..
-
24
-
-
40949105649
-
ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands
-
Weersma RK, Zhernakova A, Nolte IM, Lefebvre C, Rioux JD, Mulder F, van Dullemen HM, Kleibeuker JH, Wijmenga C, Dijkstra G. ATG16L1 and IL23R are associated with inflammatory bowel diseases but not with celiac disease in the Netherlands. Am J Gastroenterol 2008; 103: 621-627
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 621-627
-
-
Weersma, R.K.1
Zhernakova, A.2
Nolte, I.M.3
Lefebvre, C.4
Rioux, J.D.5
Mulder, F.6
van Dullemen, H.M.7
Kleibeuker, J.H.8
Wijmenga, C.9
Dijkstra, G.10
-
25
-
-
34250197591
-
IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland
-
Van Limbergen J, Russell RK, Nimmo ER, Drummond HE, Smith L, Davies G, Anderson NH, Gillett PM, McGrogan P, Hassan K, Weaver L, Bisset WM, Mahdi G, Wilson DC, Satsangi J. IL23R Arg381Gln is associated with childhood onset inflammatory bowel disease in Scotland. Gut 2007; 56: 1173-1174
-
(2007)
Gut
, vol.56
, pp. 1173-1174
-
-
Van Limbergen, J.1
Russell, R.K.2
Nimmo, E.R.3
Drummond, H.E.4
Smith, L.5
Davies, G.6
Anderson, N.H.7
Gillett, P.M.8
McGrogan, P.9
Hassan, K.10
Weaver, L.11
Bisset, W.M.12
Mahdi, G.13
Wilson, D.C.14
Satsangi, J.15
-
26
-
-
34547126695
-
-
Oliver J, Rueda B, Lopez-Nevot MA, Gomez-Garcia M, Martin J. Replication of an association between IL23R gene polymorphism with inflammatory bowel disease. Clin Gastroenterol Hepatol 2007; 5: 977-981, 981.e1-e2
-
Oliver J, Rueda B, Lopez-Nevot MA, Gomez-Garcia M, Martin J. Replication of an association between IL23R gene polymorphism with inflammatory bowel disease. Clin Gastroenterol Hepatol 2007; 5: 977-981, 981.e1-e2
-
-
-
-
27
-
-
34547436749
-
Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease
-
Baldassano RN, Bradfield JP, Monos DS, Kim CE, Glessner JT, Casalunovo T, Frackelton EC, Otieno FG, Kanterakis S, Shaner JL, Smith RM, Eckert AW, Robinson LJ, Onyiah CC, Abrams DJ, Chiavacci RM, Skraban R, Devoto M, Grant SF, Hakonarson H. Association of variants of the interleukin-23 receptor gene with susceptibility to pediatric Crohn's disease. Clin Gastroenterol Hepatol 2007; 5: 972-976
-
(2007)
Clin Gastroenterol Hepatol
, vol.5
, pp. 972-976
-
-
Baldassano, R.N.1
Bradfield, J.P.2
Monos, D.S.3
Kim, C.E.4
Glessner, J.T.5
Casalunovo, T.6
Frackelton, E.C.7
Otieno, F.G.8
Kanterakis, S.9
Shaner, J.L.10
Smith, R.M.11
Eckert, A.W.12
Robinson, L.J.13
Onyiah, C.C.14
Abrams, D.J.15
Chiavacci, R.M.16
Skraban, R.17
Devoto, M.18
Grant, S.F.19
Hakonarson, H.20
more..
-
28
-
-
37349018294
-
Evaluation of the interleukin-23 receptor gene coding variant R381Q in pediatric and adult Crohn disease
-
Leshinsky-Silver E, Karban A, Dalal I, Eliakim R, Shirin H, Tzofi T, Boaz M, Levine A. Evaluation of the interleukin-23 receptor gene coding variant R381Q in pediatric and adult Crohn disease. J Pediatr Gastroenterol Nutr 2007; 45: 405-408
-
(2007)
J Pediatr Gastroenterol Nutr
, vol.45
, pp. 405-408
-
-
Leshinsky-Silver, E.1
Karban, A.2
Dalal, I.3
Eliakim, R.4
Shirin, H.5
Tzofi, T.6
Boaz, M.7
Levine, A.8
-
29
-
-
40949096976
-
Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: Results from a case-control and family-based study among Canadian children
-
Amre DK, Mack D, Israel D, Morgan K, Lambrette P, Law L, Grimard G, Deslandres C, Krupoves A, Bucionis V, Costea I, Bissonauth V, Feguery H, D'Souza S, Levy E, Seidman EG. Association between genetic variants in the IL-23R gene and early-onset Crohn's disease: results from a case-control and family-based study among Canadian children. Am J Gastroenterol 2008; 103: 615-620
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 615-620
-
-
Amre, D.K.1
Mack, D.2
Israel, D.3
Morgan, K.4
Lambrette, P.5
Law, L.6
Grimard, G.7
Deslandres, C.8
Krupoves, A.9
Bucionis, V.10
Costea, I.11
Bissonauth, V.12
Feguery, H.13
D'Souza, S.14
Levy, E.15
Seidman, E.G.16
-
30
-
-
34249030920
-
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease
-
Dubinsky MC, Wang D, Picornell Y, Wrobel I, Katzir L, Quiros A, Dutridge D, Wahbeh G, Silber G, Bahar R, Mengesha E, Targan SR, Taylor KD, Rotter JI. IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm Bowel Dis 2007; 13: 511-515
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 511-515
-
-
Dubinsky, M.C.1
Wang, D.2
Picornell, Y.3
Wrobel, I.4
Katzir, L.5
Quiros, A.6
Dutridge, D.7
Wahbeh, G.8
Silber, G.9
Bahar, R.10
Mengesha, E.11
Targan, S.R.12
Taylor, K.D.13
Rotter, J.I.14
-
31
-
-
34548685616
-
Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis
-
Buning C, Schmidt HH, Molnar T, De Jong DJ, Fiedler T, Buhner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Buttner J, Lochs H, Witt H. Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis. Aliment Pharmacol Ther 2007; 26: 1025-1033
-
(2007)
Aliment Pharmacol Ther
, vol.26
, pp. 1025-1033
-
-
Buning, C.1
Schmidt, H.H.2
Molnar, T.3
De Jong, D.J.4
Fiedler, T.5
Buhner, S.6
Sturm, A.7
Baumgart, D.C.8
Nagy, F.9
Lonovics, J.10
Drenth, J.P.11
Landt, O.12
Nickel, R.13
Buttner, J.14
Lochs, H.15
Witt, H.16
-
32
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, Till A, Teuber M, Huse K, Albrecht M, Mayr G, De La Vega FM, Briggs J, Gunther S, Prescott NJ, Onnie CM, Hasler R, Sipos B, Folsch UR, Lengauer T, Platzer M, Mathew CG, Krawczak M, Schreiber S. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007; 39: 207-211
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
33
-
-
34548163868
-
Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene
-
Cummings JR, Cooney R, Pathan S, Anderson CA, Barrett JC, Beckly J, Geremia A, Hancock L, Guo C, Ahmad T, Cardon LR, Jewell DP. Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene. Inflamm Bowel Dis 2007; 13: 941-946
-
(2007)
Inflamm Bowel Dis
, vol.13
, pp. 941-946
-
-
Cummings, J.R.1
Cooney, R.2
Pathan, S.3
Anderson, C.A.4
Barrett, J.C.5
Beckly, J.6
Geremia, A.7
Hancock, L.8
Guo, C.9
Ahmad, T.10
Cardon, L.R.11
Jewell, D.P.12
-
34
-
-
34247566585
-
A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5
-
Prescott NJ, Fisher SA, Franke A, Hampe J, Onnie CM, Soars D, Bagnall R, Mirza MM, Sanderson J, Forbes A, Mansfield JC, Lewis CM, Schreiber S, Mathew CG. A nonsynonymous SNP in ATG16L1 predisposes to ileal Crohn's disease and is independent of CARD15 and IBD5. Gastroenterology 2007; 132: 1665-1671
-
(2007)
Gastroenterology
, vol.132
, pp. 1665-1671
-
-
Prescott, N.J.1
Fisher, S.A.2
Franke, A.3
Hampe, J.4
Onnie, C.M.5
Soars, D.6
Bagnall, R.7
Mirza, M.M.8
Sanderson, J.9
Forbes, A.10
Mansfield, J.C.11
Lewis, C.M.12
Schreiber, S.13
Mathew, C.G.14
-
35
-
-
36549062442
-
IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease
-
Roberts RL, Gearry RB, Hollis-Moffatt JE, Miller AL, Reid J, Abkevich V, Timms KM, Gutin A, Lanchbury JS, Merriman TR, Barclay ML, Kennedy MA. IL23R R381Q and ATG16L1 T300A are strongly associated with Crohn's disease in a study of New Zealand Caucasians with inflammatory bowel disease. Am J Gastroenterol 2007; 102: 2754-2761
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 2754-2761
-
-
Roberts, R.L.1
Gearry, R.B.2
Hollis-Moffatt, J.E.3
Miller, A.L.4
Reid, J.5
Abkevich, V.6
Timms, K.M.7
Gutin, A.8
Lanchbury, J.S.9
Merriman, T.R.10
Barclay, M.L.11
Kennedy, M.A.12
-
36
-
-
40949112379
-
The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population
-
Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Torok HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Goke B, Ochsenkuhn T, Mussack T, Folwaczny M, Muller-Myhsok B, Brand S. The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am J Gastroenterol 2008; 103: 682-691
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 682-691
-
-
Glas, J.1
Konrad, A.2
Schmechel, S.3
Dambacher, J.4
Seiderer, J.5
Schroff, F.6
Wetzke, M.7
Roeske, D.8
Torok, H.P.9
Tonenchi, L.10
Pfennig, S.11
Haller, D.12
Griga, T.13
Klein, W.14
Epplen, J.T.15
Folwaczny, C.16
Lohse, P.17
Goke, B.18
Ochsenkuhn, T.19
Mussack, T.20
Folwaczny, M.21
Muller-Myhsok, B.22
Brand, S.23
more..
-
37
-
-
34547211759
-
Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease
-
Baldassano RN, Bradfield JP, Monos DS, Kim CE, Glessner JT, Casalunovo T, Frackelton EC, Otieno FG, Kanterakis S, Shaner JL, Smith RM, Eckert AW, Robinson LJ, Onyiah CC, Abrams DJ, Chiavacci RM, Skraban R, Devoto M, Grant SF, Hakonarson H. Association of the T300A non-synonymous variant of the ATG16L1 gene with susceptibility to paediatric Crohn's disease. Gut 2007; 56: 1171-1173
-
(2007)
Gut
, vol.56
, pp. 1171-1173
-
-
Baldassano, R.N.1
Bradfield, J.P.2
Monos, D.S.3
Kim, C.E.4
Glessner, J.T.5
Casalunovo, T.6
Frackelton, E.C.7
Otieno, F.G.8
Kanterakis, S.9
Shaner, J.L.10
Smith, R.M.11
Eckert, A.W.12
Robinson, L.J.13
Onyiah, C.C.14
Abrams, D.J.15
Chiavacci, R.M.16
Skraban, R.17
Devoto, M.18
Grant, S.F.19
Hakonarson, H.20
more..
-
38
-
-
41149137717
-
Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe
-
Van Limbergen J, Russell RK, Nimmo ER, Drummond HE, Smith L, Anderson NH, Davies G, Gillett PM, McGrogan P, Weaver LT, Bisset WM, Mahdi G, Arnott ID, Wilson DC, Satsangi J. Autophagy gene ATG16L1 influences susceptibility and disease location but not childhood-onset in Crohn's disease in Northern Europe. Inflamm Bowel Dis 2008; 14: 338-346
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 338-346
-
-
Van Limbergen, J.1
Russell, R.K.2
Nimmo, E.R.3
Drummond, H.E.4
Smith, L.5
Anderson, N.H.6
Davies, G.7
Gillett, P.M.8
McGrogan, P.9
Weaver, L.T.10
Bisset, W.M.11
Mahdi, G.12
Arnott, I.D.13
Wilson, D.C.14
Satsangi, J.15
-
39
-
-
33846644967
-
Polymorphisms of tumor necrosis factoralpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease
-
Cucchiara S, Latiano A, Palmieri O, Canani RB, D'Inca R, Guariso G, Vieni G, De Venuto D, Riegler G, De'Angelis GL, Guagnozzi D, Bascietto C, Miele E, Valvano MR, Bossa F, Annese V. Polymorphisms of tumor necrosis factoralpha but not MDR1 influence response to medical therapy in pediatric-onset inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2007; 44: 171-179
-
(2007)
J Pediatr Gastroenterol Nutr
, vol.44
, pp. 171-179
-
-
Cucchiara, S.1
Latiano, A.2
Palmieri, O.3
Canani, R.B.4
D'Inca, R.5
Guariso, G.6
Vieni, G.7
De Venuto, D.8
Riegler, G.9
De'Angelis, G.L.10
Guagnozzi, D.11
Bascietto, C.12
Miele, E.13
Valvano, M.R.14
Bossa, F.15
Annese, V.16
-
40
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR, Caprilli R, Colombel JF, Gasche C, Geboes K, Jewell DP, Karban A, Loftus Jr EV, Pena AS, Riddell RH, Sachar DB, Schreiber S, Steinhart AH, Targan SR, Vermeire S, Warren BF. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 2005; 19 Suppl A: 5-36
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
Arnott, I.D.4
Bernstein, C.N.5
Brant, S.R.6
Caprilli, R.7
Colombel, J.F.8
Gasche, C.9
Geboes, K.10
Jewell, D.P.11
Karban, A.12
Loftus Jr, E.V.13
Pena, A.S.14
Riddell, R.H.15
Sachar, D.B.16
Schreiber, S.17
Steinhart, A.H.18
Targan, S.R.19
Vermeire, S.20
Warren, B.F.21
more..
-
41
-
-
33644924311
-
Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis
-
Palmieri O, Latiano A, Valvano R, D'Inca R, Vecchi M, Sturniolo GC, Saibeni S, Peyvandi F, Bossa F, Zagaria C, Andriulli A, Devoto M, Annese V. Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis. Aliment Pharmacol Ther 2006; 23: 497-506
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 497-506
-
-
Palmieri, O.1
Latiano, A.2
Valvano, R.3
D'Inca, R.4
Vecchi, M.5
Sturniolo, G.C.6
Saibeni, S.7
Peyvandi, F.8
Bossa, F.9
Zagaria, C.10
Andriulli, A.11
Devoto, M.12
Annese, V.13
-
42
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-265
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
43
-
-
33646397611
-
IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
-
Yen D, Cheung J, Scheerens H, Poulet F, McClanahan T, McKenzie B, Kleinschek MA, Owyang A, Mattson J, Blumenschein W, Murphy E, Sathe M, Cua DJ, Kastelein RA, Rennick D. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J Clin Invest 2006; 116: 1310-1316
-
(2006)
J Clin Invest
, vol.116
, pp. 1310-1316
-
-
Yen, D.1
Cheung, J.2
Scheerens, H.3
Poulet, F.4
McClanahan, T.5
McKenzie, B.6
Kleinschek, M.A.7
Owyang, A.8
Mattson, J.9
Blumenschein, W.10
Murphy, E.11
Sathe, M.12
Cua, D.J.13
Kastelein, R.A.14
Rennick, D.15
-
44
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, Cua DJ, Littman DR. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006; 126: 1121-1133
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov II1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
45
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL- 23R
-
Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, Pflanz S, Zhang R, Singh KP, Vega F, To W, Wagner J, O'Farrell AM, McClanahan T, Zurawski S, Hannum C, Gorman D, Rennick DM, Kastelein RA, de Waal Malefyt R, Moore KW. A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL- 23R. J Immunol 2002; 168: 5699-5708
-
(2002)
J Immunol
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
To, W.11
Wagner, J.12
O'Farrell, A.M.13
McClanahan, T.14
Zurawski, S.15
Hannum, C.16
Gorman, D.17
Rennick, D.M.18
Kastelein, R.A.19
de Waal Malefyt, R.20
Moore, K.W.21
more..
-
46
-
-
33344475671
-
Autophagy in innate and adaptive immunity against intracellular pathogens
-
Schmid D, Dengjel J, Schoor O, Stevanovic S, Munz C. Autophagy in innate and adaptive immunity against intracellular pathogens. J Mol Med 2006; 84: 194-202
-
(2006)
J Mol Med
, vol.84
, pp. 194-202
-
-
Schmid, D.1
Dengjel, J.2
Schoor, O.3
Stevanovic, S.4
Munz, C.5
-
47
-
-
35848970794
-
Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease
-
Massey DC, Parkes M. Genome-wide association scanning highlights two autophagy genes, ATG16L1 and IRGM, as being significantly associated with Crohn's disease. Autophagy 2007; 3: 649-651
-
(2007)
Autophagy
, vol.3
, pp. 649-651
-
-
Massey, D.C.1
Parkes, M.2
-
48
-
-
17744373329
-
Genetics of Crohn disease, an archetypal inflammatory barrier disease
-
Schreiber S, Rosenstiel P, Albrecht M, Hampe J, Krawczak M. Genetics of Crohn disease, an archetypal inflammatory barrier disease. Nat Rev Genet 2005; 6: 376-388
-
(2005)
Nat Rev Genet
, vol.6
, pp. 376-388
-
-
Schreiber, S.1
Rosenstiel, P.2
Albrecht, M.3
Hampe, J.4
Krawczak, M.5
|