Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

PLoS Genetics

Volumn 3, Issue 4, 2007, Pages 0538-0543

  Libioulle, Cécile ^a   Louis, Edouard ^b   Hansoul, Sarah ^a   Sandor, Cynthia ^a   Farnir, Frédéric ^a   Franchimont, Denis ^c   Vermeire, Séverine ^d   Dewit, Olivier ^e   De Vos, Martine ^f   Dixon, Anna ^g   Demarche, Bruno ^a   Gut, Ivo ^h   Heath, Simon ^h   Foglio, Mario ^h   Liang, Liming ⁱ   Laukens, Debby ^f   Mni, Myriam ^a   Zelenika, Diana ^h   Van Gossum, André ^c   Rutgeerts, Paul ^d   Belaiche, Jacques ^b   Lathrop, Mark ^h   Georges, Michel ^a   more..

^a UNIVERSITY OF LIÈGE   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c ERASME HOSPITAL   (Belgium)

^d UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^e CLINIQUES UNIVERSITAIRES SAINT LUC   (Belgium)

^f GHENT UNIVERSITY HOSPITAL   (Belgium)

^g NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^h CENTRE NATIONAL DE GÉNOTYPAGE   (France)

ⁱ Center for Statistical Genetics   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 23; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR EP4; UNCLASSIFIED DRUG; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 4; PTGER4 PROTEIN, HUMAN;

ALLELE; ARTICLE; CHROMOSOME 1; CHROMOSOME 16; CHROMOSOME 5P; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCUS; GENE MAPPING; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; CASE CONTROL STUDY; CHROMOSOME 5; CHROMOSOME MAP; COHORT ANALYSIS; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

BASE SEQUENCE; CASE-CONTROL STUDIES; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 5; COHORT STUDIES; CROHN DISEASE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; LINKAGE DISEQUILIBRIUM; MOLECULAR SEQUENCE DATA; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, PROSTAGLANDIN E; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SEQUENCE HOMOLOGY, NUCLEIC ACID;

EID: 34247579326     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0030058     Document Type: Article

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