Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection

Journal of Experimental Medicine

Volumn 194, Issue 2, 2001, Pages 181-187

  Collazo, Carmen M ^a   Yap, George S ^b   Sempowski, Gregory D ^c   Lusby, Kimberly C ^c,d   Tessarollo, Lino ^e   Vande Woude, George F ^f   Sher, Alan ^a   Taylor, Gregory A ^c,d,g  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b BROWN UNIVERSITY   (United States)

^c DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d DURHAM VA MEDICAL CENTER   (United States)

^e NATIONAL CANCER INSTITUTE   (United States)

^f VAN ANDEL RESEARCH INSTITUTE   (United States)

^g DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Bacteria; GTPase; Interferon; Protozoa; Virus

Indexed keywords

GAMMA INTERFERON; GENE PRODUCT; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE TRIPHOSPHATASE; PROTEIN IRG 47; PROTEIN LRG 47; UNCLASSIFIED DRUG;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOMEGALOVIRUS; ENDOPLASMIC RETICULUM; ESSENTIAL GENE; GENE EXPRESSION; HOST RESISTANCE; IMMUNITY; IMMUNOREGULATION; INFECTION RESISTANCE; LISTERIA MONOCYTOGENES; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; STRAIN DIFFERENCE; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; GENE EXPRESSION REGULATION; GTP-BINDING PROTEINS; HERPESVIRIDAE INFECTIONS; INTERFERON-GAMMA, RECOMBINANT; LISTERIA INFECTIONS; LISTERIA MONOCYTOGENES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUROMEGALOVIRUS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL;

EID: 0035898464     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.194.2.181     Document Type: Article

References (26)

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