Preliminary evidence for genetic anticipation in Crohn's disease

Lancet

Volumn 347, Issue 9004, 1996, Pages 798-800

  Polito II, Joseph M ^a   Rees, Renee C ^a   Childs, Barton ^a   Mendeloff, Albert I ^a   Harris, Mary L ^a   Bayless, Theodore M ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRINUCLEOTIDE;

ADOLESCENT; ADULT; AGE; ARTICLE; CROHN DISEASE; DATA ANALYSIS; DISEASE SEVERITY; DISEASE TRANSMISSION; FEMALE; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; REGRESSION ANALYSIS; RETROSPECTIVE STUDY;

EID: 0029927577     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)90870-3     Document Type: Article

References (10)

1. Monsen U, Burnell O, Johansson C, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease. Scand J Gastroenterol 1991; 26: 302-06.
2. Lashner BA, Evans AA, Kirsner JB, Hanauer SB. Prevalence and incidence of inflammatory bowel disease in family members. Gastroenterology 1986; 91: 1396-400.
3. Howeler CJ, Busch HFM, Geraedts JPM, Niermiejer MF, Stall A. Anticipation in myotonic dystrophy: fact or fiction? Brain 1989; 112: 779-97.
4. Snell R, MacMillan T, Cheadle JP, et al. Relationship between trinucleotide repeat expansion and phenotypic variation in Huntington's disease. Nature Genet 1993; 4: 393-97.
5. Maddox J. Triplet repeat genes raise questions. Nature 1994; 368: 685.
6. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics 1986; 42: 121-30.
7. Penrose LS. The problem of anticipation in pedigrees of dystrophia myotonica. Ann Eugen 1948; 14: 125-32.
8. Barclay SK, Kirschner BS. Parents developing IBD after their children - clinical features and implications for family studies. Gastroenterology 1994; 106: A658.
9. Adams P, Falek A, Arnold J. Huntington disease in Georgia: age at onset. Am J Hum Genet 1988; 43: 695-704.
10. MacDonald ME, Barnes G, Scinilhi J, et al. Gametic but not somatic instability of CAG repeat length in Huntington's disease. J Med Genet 1993; 30: 982-86.