Contribution of IBD5 locus to clinical features of IBD patients

American Journal of Gastroenterology

Volumn 101, Issue 2, 2006, Pages 318-325

  Latiano, Anna ^a   Palmieri, O ^a   Valvano, Rossella M ^a   D'Incà, Renata ^b   Vecchi, Maurizio ^c   Ferraris, Angelo ^d   Sturniolo, Giacomo C ^b   Spina, Luisa ^c   Lombardi, Giovanni ^a   Dallapiccola, Bruno ^d,e   Andriulli, Angelo ^a   Devoto, Marcella ^e,f   Annese, Vito ^a  

^a CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

^b UNIVERSITY OF PADOVA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d Ospedale CSS IRCCS   (Italy)

^e SAPIENZA UNIVERSITY OF ROME   (Italy)

^f NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15;

ADULT; AGED; ALLELE; ANALYTIC METHOD; ARTICLE; CARD15 GENE; CLINICAL FEATURE; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; GENE; GENE INTERACTION; GENE LOCUS; GENETIC EPISTASIS; GENETIC VARIABILITY; HOMOZYGOSITY; HUMAN; IBD5 GENE; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; PRIORITY JOURNAL; ULCERATIVE COLITIS; UNIVARIATE ANALYSIS;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALLELES; COLITIS, ULCERATIVE; CROHN DISEASE; DNA; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INFLAMMATORY BOWEL DISEASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MIDDLE AGED; NOD2 SIGNALING ADAPTOR PROTEIN; PHENOTYPE; POLYMERASE CHAIN REACTION; RISK FACTORS;

EID: 33644910915     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1111/j.1572-0241.2006.00389.x     Document Type: Article

References (28)

1. Podolski DK Inflammatory bowel disease N Engl J Med 2002 347 417 29
2. Hugot JP Chamaillard M Zouali H et al Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease Nature 2001 411 599 603
3. Ogura Y Bonen DK Inohara N et al A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 2001 411 603 6
4. Hampe J Cuthbert A Croucher PJ et al Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations Lancet 2001 357 1925 8
5. Vermeire S NOD2/CARD15. Relevance in clinical practice Best Pract Res Clin Gastroenterol 2004 18 569 75
6. Economou M Trikalinos TA Loizou KT et al Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: A metaanalysis Am J Gastroenterol 2004 99 2393 404
7. Ma Y Ohmen JD Li Z et al A genome-wide search identifies potential new susceptibility loci for Crohn's disease Inflamm Bowel Dis 1999 5 271 8
8. Rioux JD Daly MJ Silverberg MS et al Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn's disease Nat Genet 2001 29 223 8
9. Negoro K McGovern DP Kinouchi Y et al Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease Gut 2003 52 541 6
10. Giallourakis C Stoll M Miller K et al IBD5 is a general risk factor for inflammatory bowel disease: Replication of association with Crohn's disease and identification of a novel association with ulcerative colitis Am J Hum Genet 2003 73 205 11
11. Armuzzi A Ahmad T Ling KL et al Genotype-phenotype analysis of the Crohn's disease susceptibility haplotype on chromosome 5q31 Gut 2003 52 1133 9
12. Mirza MM Fisher SA King K et al Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn's disease Am J Hum Genet 2003 72 1018 22
13. McGovern DP Van Heel DA Negoro K et al Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis Am J Hum Genet 2003 73 1465 6
14. Urcelay E Mendoza JL Martínez A et al IBD5 polymorphisms in inflammatory bowel disease: Association with response to infliximab World J Gastroenterol 2005 11 1187 92
15. Peltekova VD Wintle RF Rubin LA et al Functional variants of OCTN cation transporter genes are associated with Crohn's disease Nat Genet 2004 36 471 5
16. Newman B Gu X Wintle R et al A risk haplotype in the solute carrier family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease Gastroenterology 2005 128 260 9
17. Gasche C Scholmerich J Brynskov J et al A simple classification of Crohn's disease: Report of a Working Party of the World Congresses of Gastroenterology, Vienna 1998 Inflamm Bowel Dis 2000 6 8 15
18. Annese V Lombardi G Perri F et al Variants of CARD15 are associated with an aggressive clinical course of Crohn's disease. An IG-IBD study Am J Gastroenterol 2005 100 84 92
19. Palmieri O Toth S Ferraris A et al CARD15 genotyping in inflammatory bowel disease patients by multiplex pyrosequencing Clin Chem 2003 49 1675 9
20. Ahmad T Satsangi J McGovern D et al Review article: The genetics of inflammatory bowel disease Aliment Pharmacol Ther 2001 15 731 48
21. Louis E Michel V Hugot JP et al Early development of stricturing or penetrating pattern in Crohn's disease is influenced by disease location, number of flares, and smoking but not by NOD2/CARD15 genotype Gut 2003 52 552 7
22. Daly MJ Rioux JD Schaffner SF et al High-resolution haplotype structure in the human genome Nat Genet 2001 29 229 32
23. Steinhart AH Girgrah N McLeod RS Reliability of a Crohn's disease clinical classification scheme based on disease behavior Inflamm Bowel Dis 1998 4 228 34
24. Louis E Collard A Oger AF et al Behaviour of Crohn's disease according to Vienna classification: Changing pattern over the course of the disease Gut 2001 49 777 82
25. Ahmad T Tamboli CP Jewell D et al Clinical relevance of advances in genetics and pharmacogenetics of IBD Gastroenterology 2004 126 1533 49
26. Cavanaugh JA IBD International Genetics Consortium: International cooperation making sense of complex disease Inflamm Bowel Dis 2003 9 190 3
27. Annese V Palmieri O Latiano A et al Variants of OCTN cation transporter gene are associated with both Crohn's disease and ulcerative colitis Gastroenterology 2005 128 T1015
28. Noble CL Nimmo ER Drummond H et al The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease Gastroenterology 2005 128 T1050