Fish oil targets PTEN to regulate NFκB for downregulation of anti-apoptotic genes in breast tumor growth

Breast Cancer Research and Treatment

Volumn 118, Issue 1, 2009, Pages 213-228

  Ghosh Choudhury, Triparna ^a   Mandal, Chandi C ^a   Woodruff, Kathleen ^a   St Clair, Patricia ^a   Fernandes, Gabriel ^a   Choudhury, Goutam G ^a,b,c   Ghosh Choudhury, Nandini ^a,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Education and Clinical Center   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

Apoptotic signal; Breast tumor growth; DHA; EPA; NF B; PTEN

Indexed keywords

CASPASE 3; FISH OIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; OMEGA 3 FATTY ACID; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN KINASE B; SYNAPTOTAGMIN I;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST TUMOR; CANCER REGRESSION; CONTROLLED STUDY; DNA BINDING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VIVO STUDY; INHIBITION KINETICS; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; XENOGRAFT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADENOCARCINOMA; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA, NEOPLASM; DOCOSAHEXAENOIC ACIDS; DOWN-REGULATION; EICOSAPENTAENOIC ACID; FEMALE; FISH OILS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BCL-2; HUMANS; MICE; MICE, NUDE; NEOPLASM PROTEINS; NF-KAPPA B; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 70349935179     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0227-7     Document Type: Article

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