Regulation of G1 progression by the PTEN tumor suppressor protein is linked to inhibition of the phosphatidylinositol 3-kinase/akt pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 5, 1999, Pages 2110-2115

  Ramaswamy, Shivapriya ^a   Nakamura, Noriaki ^a   Vazquez, Francisca ^a   Batt, David B ^a   Perera, Sauni ^a   Roberts, Thomas M ^a   Sellers, William R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INOSITOL 1,3,4,5 TETRAKISPHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOPROTEIN PHOSPHATASE; POLYPHOSPHOINOSITIDE; PROTEIN; AKT1 PROTEIN, HUMAN; MYO INOSITOL 1 (OR 4) MONOPHOSPHATASE; MYO-INOSITOL-1 (OR 4)-MONOPHOSPHATASE; ONCOPROTEIN; PHOSPHATASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE; PTEN PROTEIN, HUMAN; RECOMBINANT PROTEIN; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; COWDEN SYNDROME; DEPHOSPHORYLATION; ENZYME ACTIVITY; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOPRECIPITATION; PRIORITY JOURNAL; SOMATIC MUTATION; TUMOR SUPPRESSOR GENE; CELL CYCLE G1 PHASE; CELL LINE; CHROMOSOME 10; CHROMOSOME MAP; CONGENITAL TUMOR; DRUG ANTAGONISM; GENETIC TRANSFECTION; GENETICS; METABOLISM; NEOPLASM; PHYSIOLOGY; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

1-PHOSPHATIDYLINOSITOL 3-KINASE; CELL CYCLE; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 10; G1 PHASE; GENES, TUMOR SUPPRESSOR; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; MUTAGENESIS, SITE-DIRECTED; NEOPLASMS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 0033514509     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.5.2110     Document Type: Article

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