Oncogenic transformation induced by the p110β, -γ, and -δ isoforms of class I phosphoinositide 3-kinase

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 5, 2006, Pages 1289-1294

  Kang, Sohye ^a   Denley, Adam ^a   Vanhaesebroeck, Bart ^b,c   Vogt, Peter K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b LUDWIG INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Akt

Indexed keywords

PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE DELTA; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE P110ALPHA; PROTEIN KINASE B; PROTEIN P110; RAPAMYCIN; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SUBUNIT; GENE OVEREXPRESSION; MALIGNANT TRANSFORMATION; MUTATION; NONHUMAN; ONCOGENE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; SARCOMA VIRUS; SIGNAL TRANSDUCTION; VIRUS ONCOGENE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CELLS, CULTURED; CHICK EMBRYO; CULTURE MEDIA, SERUM-FREE; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIDS; POINT MUTATION; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN KINASES; RAS PROTEINS; SIGNAL TRANSDUCTION; SIROLIMUS; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 31944448780     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510772103     Document Type: Article

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