-
1
-
-
0030936323
-
a putative protein tyrosine phosphatase gene mutated in human brain, breast, prostate cancer
-
(Washington, DC)
-
Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science (Washington, DC), 275: 1943-1947, 1997.
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Pten, R.17
-
2
-
-
17144436629
-
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
-
Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davis, T., Frye, C., Hu, R., Swedlund, B., Teng, D.H., and Tavtigian, S.V. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers. Nat Genet., 15; 356-362, 1997.
-
(1997)
Nat Genet.
, vol.15
, pp. 356-362
-
-
Steck, P.A.1
Pershouse, M.A.2
Jasser, S.A.3
Yung, W.K.4
Lin, H.5
Ligon, A.H.6
Langford, L.A.7
Baumgard, M.L.8
Hattier, T.9
Davis, T.10
Frye, C.11
Hu, R.12
Swedlund, B.13
Teng, D.H.14
Tavtigian, S.V.15
-
3
-
-
0031001041
-
TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
-
Li, D. M., and Sun, H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res., 57: 2124-2129, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 2124-2129
-
-
Li, D.M.1
Sun, H.2
-
4
-
-
2642705040
-
Mutation of the PTEN (MMACI) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q
-
Bostrom, J., Cobbers, J. M., Wolter, M., Tabatabai, G., Weber, R. G., Lichter, P., Collins, V. P., and Reifenberger, G. Mutation of the PTEN (MMACI) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res., 58: 29-33, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 29-33
-
-
Bostrom, J.1
Cobbers, J.M.2
Wolter, M.3
Tabatabai, G.4
Weber, R.G.5
Lichter, P.6
Collins, V.P.7
Reifenberger, G.8
-
5
-
-
0030724320
-
PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas
-
Liu, W., James, C. D., Frederick, L., Alderete, B. E., and Jenkins, R. B. PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas. Cancer Res., 57: 5254-5257, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 5254-5257
-
-
Liu, W.1
James, C.D.2
Frederick, L.3
Alderete, B.E.4
Jenkins, R.B.5
-
6
-
-
0030817576
-
PTEN gene mutations are seen in high-grade but not in low-grade gliomas
-
Rasheed, B. K., Stenzel, T. T., McLendon, R. E., Parsons, R., Friedman, A. H., Friedman, H. S., Bigner, D. D., and Bigner, S. H. PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res., 57: 4187-4190, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4187-4190
-
-
Rasheed, B.K.1
Stenzel, T.T.2
McLendon, R.E.3
Parsons, R.4
Friedman, A.H.5
Friedman, H.S.6
Bigner, D.D.7
Bigner, S.H.8
-
7
-
-
0030799909
-
Somatic mutations of PTEN in glioblastoma multiforme
-
Wang, S. I., Puc. J., Li, J., Brace, J. N., Cairns, P., Sidransky, D., and Parsons, R. Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res., 57: 4183-4186, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4183-4186
-
-
Wang, S.I.1
Puc, J.2
Li, J.3
Brace, J.N.4
Cairns, P.5
Sidransky, D.6
Parsons, R.7
-
8
-
-
7144223432
-
PTEN mutations in gliomas and glioneuronal tumors
-
Duerr, E. M., Rollbrocker, B., Hayashi, Y., Peters, N., Meyer-Puttlitz, B., Louis, D. N., Schramm, J., Wiestler, O. D., Parsons, R., Eng, C., and von Deimling, A. PTEN mutations in gliomas and glioneuronal tumors. Oncogene, 16: 2259-2264, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 2259-2264
-
-
Duerr, E.M.1
Rollbrocker, B.2
Hayashi, Y.3
Peters, N.4
Meyer-Puttlitz, B.5
Louis, D.N.6
Schramm, J.7
Wiestler, O.D.8
Parsons, R.9
Eng, C.10
Von Deimling, A.11
-
9
-
-
0032971251
-
Mutational analysis of the PTEN gene in gliomas: Molecular and pathological correlations
-
Zhou, X. P., Li, Y. J., Hoang-Xuan, K., Laurent-Puig, P., Mokhtari, K., Longy, M., Sanson, M., Delattre, J. Y., Thomas, G., and Hamelin, R. Mutational analysis of the PTEN gene in gliomas: molecular and pathological correlations. Int. J. Cancer, 84: 150-154, 1999.
-
(1999)
Int. J. Cancer
, vol.84
, pp. 150-154
-
-
Zhou, X.P.1
Li, Y.J.2
Hoang-Xuan, K.3
Laurent-Puig, P.4
Mokhtari, K.5
Longy, M.6
Sanson, M.7
Delattre, J.Y.8
Thomas, G.9
Hamelin, R.10
-
10
-
-
15444349266
-
Frequent inactivation of PTEN/ MMAC1 in primary prostate cancer
-
Cairns, P., Okami, K., Halachmi, S., Halachmi, N., Esteller, M., Herman, J. G., Jen, J., Isaacs, W. B., Bova, G. S., and Sidransky, D. Frequent inactivation of PTEN/ MMAC1 in primary prostate cancer. Cancer Res., 57: 4997-5000, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4997-5000
-
-
Cairns, P.1
Okami, K.2
Halachmi, S.3
Halachmi, N.4
Esteller, M.5
Herman, J.G.6
Jen, J.7
Isaacs, W.B.8
Bova, G.S.9
Sidransky, D.10
-
11
-
-
0030730905
-
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
-
Dahia, P. L., Marsh, D. J., Zheng, Z., Zedenius, J., Komminoth, P., Frisk, T., Wallin, G., Parsons, R., Longy, M., Larsson, C., and Eng, C. Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res., 57: 4710-4713, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4710-4713
-
-
Dahia, P.L.1
Marsh, D.J.2
Zheng, Z.3
Zedenius, J.4
Komminoth, P.5
Frisk, T.6
Wallin, G.7
Parsons, R.8
Longy, M.9
Larsson, C.10
Eng, C.11
-
12
-
-
14444269482
-
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines
-
Teng, D. H., Hu, R., Lin, H., Davis, T., Iliev, D., Frye, C., Swedlund, B., Hansen, K. L., Vinson, V. L., Gumpper, K. L., Ellis, L., El-Naggar, A., Frazier, M., Jasser, S., Langford, L. A., Lee, J., Mills, G. B., Pershouse, M. A., Pollack, R. E., Tornos, C., Troncoso, P., Yung, W. K., Fujii, G., Berson, A., Bookstein, R., Bolen, J. B., Tavtigian, S. V., and Steck, P. A. MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines. Cancer Res., 57: 5221-5225, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 5221-5225
-
-
Teng, D.H.1
Hu, R.2
Lin, H.3
Davis, T.4
Iliev, D.5
Frye, C.6
Swedlund, B.7
Hansen, K.L.8
Vinson, V.L.9
Gumpper, K.L.10
Ellis, L.11
El-Naggar, A.12
Frazier, M.13
Jasser, S.14
Langford, L.A.15
Lee, J.16
Mills, G.B.17
Pershouse, M.A.18
Pollack, R.E.19
Tornos, C.20
Troncoso, P.21
Yung, W.K.22
Fujii, G.23
Berson, A.24
Bookstein, R.25
Bolen, J.B.26
Tavtigian, S.V.27
Steck, P.A.28
more..
-
13
-
-
0030781053
-
PTEN/MMAC1 mutations in endometrial cancers
-
Risinger, J. I., Hayes, A. K., Berchuck, A., and Barrett, J. C. PTEN/MMAC1 mutations in endometrial cancers. Cancer Res., 57: 4736-4738, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 4736-4738
-
-
Risinger, J.I.1
Hayes, A.K.2
Berchuck, A.3
Barrett, J.C.4
-
14
-
-
0032422644
-
PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics
-
Risinger, J. I., Hayes, K., Maxwell, G. L., Carney, M. E., Dodge, R. K., Barrett, J. C., and Berchuck, A. PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics. Clin. Cancer Res., 4: 3005-3010, 1998.
-
(1998)
Clin. Cancer Res.
, vol.4
, pp. 3005-3010
-
-
Risinger, J.I.1
Hayes, K.2
Maxwell, G.L.3
Carney, M.E.4
Dodge, R.K.5
Barrett, J.C.6
Berchuck, A.7
-
15
-
-
0030761409
-
Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
-
Tashiro, H., Blazes, M. S., Wu, R., Cho, K. R., Bose, S., Wang, S. I., Li, J., Parsons, R., and Ellenson, L. H. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res., 57: 3935-3940, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 3935-3940
-
-
Tashiro, H.1
Blazes, M.S.2
Wu, R.3
Cho, K.R.4
Bose, S.5
Wang, S.I.6
Li, J.7
Parsons, R.8
Ellenson, L.H.9
-
16
-
-
17344368045
-
Germline PTEN mutations in Cowden syndrome-like families
-
Marsh, D. J., Dahia, P. L., Caron, S., Kum, J. B., Frayling, I. M., Tomlinson, I. P., Hughes, K. S., Eeles, R. A., Hodgson, S. V., Murday, V. A., Houlston, R., and Eng, C. Germline PTEN mutations in Cowden syndrome-like families. J. Med. Genet., 35: 881-885, 1998.
-
(1998)
J. Med. Genet.
, vol.35
, pp. 881-885
-
-
Marsh, D.J.1
Dahia, P.L.2
Caron, S.3
Kum, J.B.4
Frayling, I.M.5
Tomlinson, I.P.6
Hughes, K.S.7
Eeles, R.A.8
Hodgson, S.V.9
Murday, V.A.10
Houlston, R.11
Eng, C.12
-
17
-
-
0032577699
-
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
-
Maehama, T., and Dixon, J. E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273: 13375-13378, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 13375-13378
-
-
Maehama, T.1
Dixon, J.E.2
-
18
-
-
0032475861
-
Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN
-
Stambolic, V., Suzuki, A., de la Pompa, J. L., Brothers, G. M., Mirtsos, C., Sasaki, T., Ruland, J., Penninger, J. M., Siderovski, D. P., and Mak, T. W. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell, 95: 29-39, 1998.
-
(1998)
Cell
, vol.95
, pp. 29-39
-
-
Stambolic, V.1
Suzuki, A.2
De La Pompa, J.L.3
Brothers, G.M.4
Mirtsos, C.5
Sasaki, T.6
Ruland, J.7
Penninger, J.M.8
Siderovski, D.P.9
Mak, T.W.10
-
19
-
-
0033152165
-
Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
-
Davies, M. A., Koul, D., Dhesi, H., Berman, R., McDonnell, T. J., McConkey, D., Yung, W. K., and Steck, P. A. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res., 59: 2551-2556, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 2551-2556
-
-
Davies, M.A.1
Koul, D.2
Dhesi, H.3
Berman, R.4
McDonnell, T.J.5
McConkey, D.6
Yung, W.K.7
Steck, P.A.8
-
21
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
-
Sun, H., Lesche, R., Li, D. M., Liliental, J., Zhang, H., Gao, J., Gavrilova, N., Mueller, B., Liu, X., and Wu, H. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc. Natl. Acad. Sci. USA, 96: 6199-6204, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
22
-
-
0033571477
-
1 arrest followed by cell death
-
1 arrest followed by cell death. Cancer Res., 59: 5808-5814, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 5808-5814
-
-
Weng, L.P.1
Smith, W.M.2
Dahia, P.L.3
Ziebold, U.4
Gil, E.5
Lees, J.A.6
Eng, C.7
-
23
-
-
0032486198
-
Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
-
(Washington, DC)
-
Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K. M. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science (Washington, DC), 280: 1614-1617, 1998.
-
(1998)
Science
, vol.280
, pp. 1614-1617
-
-
Tamura, M.1
Gu, J.2
Matsumoto, K.3
Aota, S.4
Parsons, R.5
Yamada, K.M.6
-
24
-
-
0031004088
-
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
-
Liaw, D., Marsh, D. J., Li, J., Dahia, P. L., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacocke, M., Eng, C., and Parsons, R. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat. Genet., 16: 64-67, 1997.
-
(1997)
Nat. Genet.
, vol.16
, pp. 64-67
-
-
Liaw, D.1
Marsh, D.J.2
Li, J.3
Dahia, P.L.4
Wang, S.I.5
Zheng, Z.6
Bose, S.7
Call, K.M.8
Tsou, H.C.9
Peacocke, M.10
Eng, C.11
Parsons, R.12
-
25
-
-
0031883606
-
Genetics of Cowden syndrome: Through the looking glass of oncology
-
Eng, C. Genetics of Cowden syndrome: through the looking glass of oncology. Int. J. Oncol., 12: 701-710, 1998.
-
(1998)
Int. J. Oncol.
, vol.12
, pp. 701-710
-
-
Eng, C.1
-
26
-
-
0032853452
-
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome
-
Marsh, D. J., Kum, J. B., Lunetta, K. L., Bennett, M. J., Gorlin, R. J., Ahmed, S. F., Bodurtha, J., Crowe, C., Curtis, M. A., Dasouki, M., Dunn, T., Feit, H., Geraghty, M. T., Graham, J. M., Jr., Hodgson, S. V., Hunter, A., Korf, B. R., Manchester, D., Miesfeldt, S., Murday, V. A., Nathanson, K. L., Parisi, M., Pober, B., Romano, C., Tolmie, J. L., Trembath, R., Winter, R. M., Zackal, E. H., Zori, R. T., Weng, L-P., Dahia, P. L. M., and Eng, C. PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome. Hum. Mol. Genet., 8: 1461-1472, 1999.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1461-1472
-
-
Marsh, D.J.1
Kum, J.B.2
Lunetta, K.L.3
Bennett, M.J.4
Gorlin, R.J.5
Ahmed, S.F.6
Bodurtha, J.7
Crowe, C.8
Curtis, M.A.9
Dasouki, M.10
Dunn, T.11
Feit, H.12
Geraghty, M.T.13
Graham J.M., Jr.14
Hodgson, S.V.15
Hunter, A.16
Korf, B.R.17
Manchester, D.18
Miesfeldt, S.19
Murday, V.A.20
Nathanson, K.L.21
Parisi, M.22
Pober, B.23
Romano, C.24
Tolmie, J.L.25
Trembath, R.26
Winter, R.M.27
Zackal, E.H.28
Zori, R.T.29
Weng, L.-P.30
Dahia, P.L.M.31
Eng, C.32
more..
-
27
-
-
6844252284
-
Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation
-
Marsh, D. J., Coulon, V., Lunetta, K. L., Rocca-Serra, P., Dahia, P. L., Zheng, Z., Liaw, D., Caron, S., Duboue, B., Lin, A. Y., Richardson, A. L., Bonnetblanc, J. M., Bressieux, J. M., Cabarrot-Moreau, A., Chompret, A., Demange, L., Eeles, R. A., Yahanda, A. M., Fearon, E. R., Fricker, J. P., Gorlin, R. J., Hodgson, S. V., Huson, S., Lacombe, D., Eng, C., et al. Mutation spectrum and genotype-phenotype analyses in Cowden disease and Bannayan-Zonana syndrome, two hamartoma syndromes with germline PTEN mutation. Hum. Mol. Genet., 7: 507-515, 1998.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 507-515
-
-
Marsh, D.J.1
Coulon, V.2
Lunetta, K.L.3
Rocca-Serra, P.4
Dahia, P.L.5
Zheng, Z.6
Liaw, D.7
Caron, S.8
Duboue, B.9
Lin, A.Y.10
Richardson, A.L.11
Bonnetblanc, J.M.12
Bressieux, J.M.13
Cabarrot-Moreau, A.14
Chompret, A.15
Demange, L.16
Eeles, R.A.17
Yahanda, A.M.18
Fearon, E.R.19
Fricker, J.P.20
Gorlin, R.J.21
Hodgson, S.V.22
Huson, S.23
Lacombe, D.24
Eng, C.25
more..
-
28
-
-
0031203265
-
Germline mutations in PTEN are present in Bannayan-Zonana syndrome
-
Marsh, D. J., Dahia, P. L., Zheng, Z., Liaw, D., Parsons, R., Gorlin, R. J., and Eng, C. Germline mutations in PTEN are present in Bannayan-Zonana syndrome. Nat. Genet., 16: 333-334, 1997.
-
(1997)
Nat. Genet.
, vol.16
, pp. 333-334
-
-
Marsh, D.J.1
Dahia, P.L.2
Zheng, Z.3
Liaw, D.4
Parsons, R.5
Gorlin, R.J.6
Eng, C.7
-
29
-
-
13144249184
-
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice
-
Suzuki, A., de la Pompa, J. L., Stambolic, V., Elia, A. J., Sasaki, T., del Barco Barrantes, I., Ho, A., Wakeham, A., Itie, A., Khoo, W., Fukumoto, M., and Mak, T. W. High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice. Curr. Biol., 8: 1169-1178, 1998.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1169-1178
-
-
Suzuki, A.1
De La Pompa, J.L.2
Stambolic, V.3
Elia, A.J.4
Sasaki, T.5
Del Barco Barrantes, I.6
Ho, A.7
Wakeham, A.8
Itie, A.9
Khoo, W.10
Fukumoto, M.11
Mak, T.W.12
-
30
-
-
13044250465
-
Mutation of Pten/ Mmacl in mice causes neoplasia in multiple organ systems
-
Podsypanina, K., Ellenson, L. H., Nemes, A., Gu, J., Tamura, M., Yamada, K. M., Cordon-Cardo, C., Catoretti, G., Fisher, P. E., and Parsons, R. Mutation of Pten/ Mmacl in mice causes neoplasia in multiple organ systems. Proc. Natl. Acad. Sci. USA, 96: 1563-1568, 1999.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 1563-1568
-
-
Podsypanina, K.1
Ellenson, L.H.2
Nemes, A.3
Gu, J.4
Tamura, M.5
Yamada, K.M.6
Cordon-Cardo, C.7
Catoretti, G.8
Fisher, P.E.9
Parsons, R.10
-
31
-
-
0032843540
-
Impaired Fas response and autoimmunity in Pten+/- mice
-
(Washington, DC)
-
Di Cristofano, A., Kotsi, P., Peng, Y. F., Cordon-Cardo, C., Elkon, K. B., and Pandolfi, P. P. Impaired Fas response and autoimmunity in Pten+/- mice. Science (Washington, DC), 285: 2122-2125, 1999.
-
(1999)
Science
, vol.285
, pp. 2122-2125
-
-
Di Cristofano, A.1
Kotsi, P.2
Peng, Y.F.3
Cordon-Cardo, C.4
Elkon, K.B.5
Pandolfi, P.P.6
-
32
-
-
0343657258
-
-
Lyon, France: IARC
-
Turusov, V. S. and Mohr, U. Tumors of the Mouse. Pathology of Tumors in Laboratory Animals, Ed. 2, Vol. 2, pp. 47-100. Lyon, France: IARC, 1994.
-
(1994)
Tumors of the Mouse. Pathology of Tumors in Laboratory Animals, Ed. 2
, vol.2
, pp. 47-100
-
-
Turusov, V.S.1
Mohr, U.2
-
33
-
-
0032898096
-
PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies
-
Dahia, P. L., Aguiar, R. C., Alberta, J., Kum, J. B., Caron, S., Sill, H., Marsh, D. J., Ritz, J., Freedman, A., Stiles, C., and Eng, C. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies. Hum. Mol. Genet., 8: 185-193, 1999.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 185-193
-
-
Dahia, P.L.1
Aguiar, R.C.2
Alberta, J.3
Kum, J.B.4
Caron, S.5
Sill, H.6
Marsh, D.J.7
Ritz, J.8
Freedman, A.9
Stiles, C.10
Eng, C.11
-
34
-
-
0023945139
-
Thymic lymphoma induction by the AKT8 murine retrovirus
-
Staal, S. P., and Hartley, J. W. Thymic lymphoma induction by the AKT8 murine retrovirus. J. Exp. Med., 167: 1259-1264, 1988.
-
(1988)
J. Exp. Med.
, vol.167
, pp. 1259-1264
-
-
Staal, S.P.1
Hartley, J.W.2
-
35
-
-
0031831731
-
PTEN and inherited hamartoma-cancer syndromes
-
Eng, C., and Peacocke, M. PTEN and inherited hamartoma-cancer syndromes. Nat. Genet., 19: 223, 1998.
-
(1998)
Nat. Genet.
, vol.19
, pp. 223
-
-
Eng, C.1
Peacocke, M.2
-
36
-
-
0031975070
-
Clinical and pathological features of breast disease in Cowden's syndrome: An underrecognized syndrome with an increased risk of breast cancer
-
Schrager, C. A., Schneider, D., Gruener, A. C., Tsou, H. C., and Peacocke, M. Clinical and pathological features of breast disease in Cowden's syndrome: an underrecognized syndrome with an increased risk of breast cancer. Hum. Pathol., 29: 47-53, 1998.
-
(1998)
Hum. Pathol.
, vol.29
, pp. 47-53
-
-
Schrager, C.A.1
Schneider, D.2
Gruener, A.C.3
Tsou, H.C.4
Peacocke, M.5
-
37
-
-
0032857217
-
Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast
-
Perren, A., Weng, L. P., Boag, A. H., Ziebold, U., Thakore, K., Dahia, P. L., Komminoth, P., Lees, J. A., Mulligan, L. M., Mutter, G. L., and Eng, C. Immunohistochemical evidence of loss of PTEN expression in primary ductal adenocarcinomas of the breast. Am. J. Pathol., 155: 1253-1260, 1999.
-
(1999)
Am. J. Pathol.
, vol.155
, pp. 1253-1260
-
-
Perren, A.1
Weng, L.P.2
Boag, A.H.3
Ziebold, U.4
Thakore, K.5
Dahia, P.L.6
Komminoth, P.7
Lees, J.A.8
Mulligan, L.M.9
Mutter, G.L.10
Eng, C.11
-
38
-
-
0033200172
-
Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
-
McMenamin, M. E., Soung, P., Perera, S., Kaplan, I., Loda, M., and Sellers, W. R. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res., 59: 4291-4296, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 4291-4296
-
-
McMenamin, M.E.1
Soung, P.2
Perera, S.3
Kaplan, I.4
Loda, M.5
Sellers, W.R.6
-
39
-
-
0032126505
-
Frequent inactivation of PTEN in prostate cancer cell lines and xenografts
-
Vlietstra, R. J., van Alewijk, D. C., Hermans, K. G., van Steenbrugge, G. J., and Trapman, J. Frequent inactivation of PTEN in prostate cancer cell lines and xenografts. Cancer Res., 58: 2720-2723, 1998.
-
(1998)
Cancer Res.
, vol.58
, pp. 2720-2723
-
-
Vlietstra, R.J.1
Van Alewijk, D.C.2
Hermans, K.G.3
Van Steenbrugge, G.J.4
Trapman, J.5
-
40
-
-
0032558822
-
Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
-
Haas-Kogan, D., Shalev, N., Wong, M., Mills, G., Yount, G., and Stokoe, D. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr. Biol., 8: 1195-1198, 1998.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1195-1198
-
-
Haas-Kogan, D.1
Shalev, N.2
Wong, M.3
Mills, G.4
Yount, G.5
Stokoe, D.6
-
41
-
-
0026667730
-
AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
-
Cheng, J. Q., Godwin, A. K., Bellacosa, A., Taguchi, T., Franke, T. F., Hamilton, T. C., Tsichlis, P. N., and Testa, J. R. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc. Natl. Acad. Sci. USA, 89: 9267-9271, 1992.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 9267-9271
-
-
Cheng, J.Q.1
Godwin, A.K.2
Bellacosa, A.3
Taguchi, T.4
Franke, T.F.5
Hamilton, T.C.6
Tsichlis, P.N.7
Testa, J.R.8
-
42
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
Cheng, J. Q., Ruggeri, B., Klein, W. M., Sonoda, G., Altomare, D. A., Watson, D. K., and Testa, J. R. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc. Natl. Acad. Sci. USA, 93: 3636-3641, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA, 93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
Sonoda, G.4
Altomare, D.A.5
Watson, D.K.6
Testa, J.R.7
-
43
-
-
0029127042
-
Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas
-
Bellacosa, A., de Feo, D., Godwin, A. K., Bell, D. W., Cheng, J. Q., Altomare, D. A., Wan, M., Dubeau, L., Scambia, G., and Masciullo, V. Molecular alterations of the AKT2 oncogene in ovarian and breast carcinomas. Int. J. Cancer, 64: 280-285, 1995.
-
(1995)
Int. J. Cancer
, vol.64
, pp. 280-285
-
-
Bellacosa, A.1
De Feo, D.2
Godwin, A.K.3
Bell, D.W.4
Cheng, J.Q.5
Altomare, D.A.6
Wan, M.7
Dubeau, L.8
Scambia, G.9
Masciullo, V.10
-
44
-
-
0033618371
-
Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
-
Nakatani, K., Thompson, D. A., Barthel, A., Sakaue, H., Liu, W., Weigel, R. J., and Roth, R. A. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J. Biol. Chem., 274: 21528-21532, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 21528-21532
-
-
Nakatani, K.1
Thompson, D.A.2
Barthel, A.3
Sakaue, H.4
Liu, W.5
Weigel, R.J.6
Roth, R.A.7
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