메뉴 건너뛰기




Volumn 60, Issue 13, 2000, Pages 3605-3611

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten(+/-) mice

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CANCER GENETICS; CANCER INCIDENCE; COWDEN SYNDROME; ENDOMETRIUM CANCER; ENDOMETRIUM HYPERPLASIA; FEMALE; GENE LOCUS; GENE MUTATION; HETEROZYGOSITY LOSS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE;

EID: 0034234268     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (328)

References (44)
  • 3
    • 0031001041 scopus 로고    scopus 로고
    • TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β
    • Li, D. M., and Sun, H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res., 57: 2124-2129, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 2124-2129
    • Li, D.M.1    Sun, H.2
  • 4
    • 2642705040 scopus 로고    scopus 로고
    • Mutation of the PTEN (MMACI) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q
    • Bostrom, J., Cobbers, J. M., Wolter, M., Tabatabai, G., Weber, R. G., Lichter, P., Collins, V. P., and Reifenberger, G. Mutation of the PTEN (MMACI) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res., 58: 29-33, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 29-33
    • Bostrom, J.1    Cobbers, J.M.2    Wolter, M.3    Tabatabai, G.4    Weber, R.G.5    Lichter, P.6    Collins, V.P.7    Reifenberger, G.8
  • 5
    • 0030724320 scopus 로고    scopus 로고
    • PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas
    • Liu, W., James, C. D., Frederick, L., Alderete, B. E., and Jenkins, R. B. PTEN/ MMAC1 mutations and EGFR amplification in glioblastomas. Cancer Res., 57: 5254-5257, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 5254-5257
    • Liu, W.1    James, C.D.2    Frederick, L.3    Alderete, B.E.4    Jenkins, R.B.5
  • 14
    • 0032422644 scopus 로고    scopus 로고
    • PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics
    • Risinger, J. I., Hayes, K., Maxwell, G. L., Carney, M. E., Dodge, R. K., Barrett, J. C., and Berchuck, A. PTEN mutation in endometrial cancers is associated with favorable clinical and pathologic characteristics. Clin. Cancer Res., 4: 3005-3010, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 3005-3010
    • Risinger, J.I.1    Hayes, K.2    Maxwell, G.L.3    Carney, M.E.4    Dodge, R.K.5    Barrett, J.C.6    Berchuck, A.7
  • 15
    • 0030761409 scopus 로고    scopus 로고
    • Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies
    • Tashiro, H., Blazes, M. S., Wu, R., Cho, K. R., Bose, S., Wang, S. I., Li, J., Parsons, R., and Ellenson, L. H. Mutations in PTEN are frequent in endometrial carcinoma but rare in other common gynecological malignancies. Cancer Res., 57: 3935-3940, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 3935-3940
    • Tashiro, H.1    Blazes, M.S.2    Wu, R.3    Cho, K.R.4    Bose, S.5    Wang, S.I.6    Li, J.7    Parsons, R.8    Ellenson, L.H.9
  • 17
    • 0032577699 scopus 로고    scopus 로고
    • The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
    • Maehama, T., and Dixon, J. E. The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J. Biol. Chem., 273: 13375-13378, 1998.
    • (1998) J. Biol. Chem. , vol.273 , pp. 13375-13378
    • Maehama, T.1    Dixon, J.E.2
  • 19
    • 0033152165 scopus 로고    scopus 로고
    • Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN
    • Davies, M. A., Koul, D., Dhesi, H., Berman, R., McDonnell, T. J., McConkey, D., Yung, W. K., and Steck, P. A. Regulation of Akt/PKB activity, cellular growth, and apoptosis in prostate carcinoma cells by MMAC/PTEN. Cancer Res., 59: 2551-2556, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 2551-2556
    • Davies, M.A.1    Koul, D.2    Dhesi, H.3    Berman, R.4    McDonnell, T.J.5    McConkey, D.6    Yung, W.K.7    Steck, P.A.8
  • 21
    • 13044305289 scopus 로고    scopus 로고
    • PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
    • Sun, H., Lesche, R., Li, D. M., Liliental, J., Zhang, H., Gao, J., Gavrilova, N., Mueller, B., Liu, X., and Wu, H. PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc. Natl. Acad. Sci. USA, 96: 6199-6204, 1999.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 6199-6204
    • Sun, H.1    Lesche, R.2    Li, D.M.3    Liliental, J.4    Zhang, H.5    Gao, J.6    Gavrilova, N.7    Mueller, B.8    Liu, X.9    Wu, H.10
  • 23
    • 0032486198 scopus 로고    scopus 로고
    • Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN
    • (Washington, DC)
    • Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K. M. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science (Washington, DC), 280: 1614-1617, 1998.
    • (1998) Science , vol.280 , pp. 1614-1617
    • Tamura, M.1    Gu, J.2    Matsumoto, K.3    Aota, S.4    Parsons, R.5    Yamada, K.M.6
  • 25
    • 0031883606 scopus 로고    scopus 로고
    • Genetics of Cowden syndrome: Through the looking glass of oncology
    • Eng, C. Genetics of Cowden syndrome: through the looking glass of oncology. Int. J. Oncol., 12: 701-710, 1998.
    • (1998) Int. J. Oncol. , vol.12 , pp. 701-710
    • Eng, C.1
  • 33
    • 0032898096 scopus 로고    scopus 로고
    • PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies
    • Dahia, P. L., Aguiar, R. C., Alberta, J., Kum, J. B., Caron, S., Sill, H., Marsh, D. J., Ritz, J., Freedman, A., Stiles, C., and Eng, C. PTEN is inversely correlated with the cell survival factor Akt/PKB and is inactivated via multiple mechanisms in haematological malignancies. Hum. Mol. Genet., 8: 185-193, 1999.
    • (1999) Hum. Mol. Genet. , vol.8 , pp. 185-193
    • Dahia, P.L.1    Aguiar, R.C.2    Alberta, J.3    Kum, J.B.4    Caron, S.5    Sill, H.6    Marsh, D.J.7    Ritz, J.8    Freedman, A.9    Stiles, C.10    Eng, C.11
  • 34
    • 0023945139 scopus 로고
    • Thymic lymphoma induction by the AKT8 murine retrovirus
    • Staal, S. P., and Hartley, J. W. Thymic lymphoma induction by the AKT8 murine retrovirus. J. Exp. Med., 167: 1259-1264, 1988.
    • (1988) J. Exp. Med. , vol.167 , pp. 1259-1264
    • Staal, S.P.1    Hartley, J.W.2
  • 35
    • 0031831731 scopus 로고    scopus 로고
    • PTEN and inherited hamartoma-cancer syndromes
    • Eng, C., and Peacocke, M. PTEN and inherited hamartoma-cancer syndromes. Nat. Genet., 19: 223, 1998.
    • (1998) Nat. Genet. , vol.19 , pp. 223
    • Eng, C.1    Peacocke, M.2
  • 36
    • 0031975070 scopus 로고    scopus 로고
    • Clinical and pathological features of breast disease in Cowden's syndrome: An underrecognized syndrome with an increased risk of breast cancer
    • Schrager, C. A., Schneider, D., Gruener, A. C., Tsou, H. C., and Peacocke, M. Clinical and pathological features of breast disease in Cowden's syndrome: an underrecognized syndrome with an increased risk of breast cancer. Hum. Pathol., 29: 47-53, 1998.
    • (1998) Hum. Pathol. , vol.29 , pp. 47-53
    • Schrager, C.A.1    Schneider, D.2    Gruener, A.C.3    Tsou, H.C.4    Peacocke, M.5
  • 38
    • 0033200172 scopus 로고    scopus 로고
    • Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage
    • McMenamin, M. E., Soung, P., Perera, S., Kaplan, I., Loda, M., and Sellers, W. R. Loss of PTEN expression in paraffin-embedded primary prostate cancer correlates with high Gleason score and advanced stage. Cancer Res., 59: 4291-4296, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 4291-4296
    • McMenamin, M.E.1    Soung, P.2    Perera, S.3    Kaplan, I.4    Loda, M.5    Sellers, W.R.6
  • 40
    • 0032558822 scopus 로고    scopus 로고
    • Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC
    • Haas-Kogan, D., Shalev, N., Wong, M., Mills, G., Yount, G., and Stokoe, D. Protein kinase B (PKB/Akt) activity is elevated in glioblastoma cells due to mutation of the tumor suppressor PTEN/MMAC. Curr. Biol., 8: 1195-1198, 1998.
    • (1998) Curr. Biol. , vol.8 , pp. 1195-1198
    • Haas-Kogan, D.1    Shalev, N.2    Wong, M.3    Mills, G.4    Yount, G.5    Stokoe, D.6
  • 41
    • 0026667730 scopus 로고
    • AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas
    • Cheng, J. Q., Godwin, A. K., Bellacosa, A., Taguchi, T., Franke, T. F., Hamilton, T. C., Tsichlis, P. N., and Testa, J. R. AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas. Proc. Natl. Acad. Sci. USA, 89: 9267-9271, 1992.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9267-9271
    • Cheng, J.Q.1    Godwin, A.K.2    Bellacosa, A.3    Taguchi, T.4    Franke, T.F.5    Hamilton, T.C.6    Tsichlis, P.N.7    Testa, J.R.8
  • 44
    • 0033618371 scopus 로고    scopus 로고
    • Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines
    • Nakatani, K., Thompson, D. A., Barthel, A., Sakaue, H., Liu, W., Weigel, R. J., and Roth, R. A. Up-regulation of Akt3 in estrogen receptor-deficient breast cancers and androgen-independent prostate cancer lines. J. Biol. Chem., 274: 21528-21532, 1999.
    • (1999) J. Biol. Chem. , vol.274 , pp. 21528-21532
    • Nakatani, K.1    Thompson, D.A.2    Barthel, A.3    Sakaue, H.4    Liu, W.5    Weigel, R.J.6    Roth, R.A.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.