-
1
-
-
0032981481
-
Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes
-
McConnell B.B., Gregory F.J., Stott F.J., Hara E., Peters G. 1999. Induced expression of p16(INK4a) inhibits both CDK4- and CDK2-associated kinase activity by reassortment of cyclin-CDK-inhibitor complexes. Mol. Cell. Biol. 19, 1981-1989.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1981-1989
-
-
McConnell, B.B.1
Gregory, F.J.2
Stott, F.J.3
Hara, E.4
Peters, G.5
-
3
-
-
0027339342
-
An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae
-
Mendenhall M.D. 1993. An inhibitor of p34CDC28 protein kinase activity from Saccharomyces cerevisiae. Science. 259, 216-219.
-
(1993)
Science
, vol.259
, pp. 216-219
-
-
Mendenhall, M.D.1
-
4
-
-
0030693702
-
Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast
-
Henchoz S., Chi Y., Catarin B., Herskowitz I., Deshaies R., Peter M. 1997. Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev. 11, 3046-3060.
-
(1997)
Genes Dev.
, vol.11
, pp. 3046-3060
-
-
Henchoz, S.1
Chi, Y.2
Catarin, B.3
Herskowitz, I.4
Deshaies, R.5
Peter, M.6
-
5
-
-
0027731971
-
Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit
-
Gu Y., Turck C.W., Morgan D.O. 1993. Inhibition of CDK2 activity in vivo by an associated 20K regulatory subunit. Nature. 366, 707-710.
-
(1993)
Nature
, vol.366
, pp. 707-710
-
-
Gu, Y.1
Turck, C.W.2
Morgan, D.O.3
-
6
-
-
0027496935
-
Th p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper J.W., Adami G.R., Wei N., Keyomarsi K., Elledge S.J. 1993. Th p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell. 75, 805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.R.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
7
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y., Hannon G.J., Zhang H., Casso D., Kobayashi R., Beach D. 1993. p21 is a universal inhibitor of cyclin kinases. Nature. 366, 701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, H.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
8
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry W.S., Tokino T., Velculescu V.E., Levy D.B., Parsons R., Trent J.M., Lin D., Mercer W.E., Kinzler K.W., Vogelstein B. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell. 75, 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
9
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda A., Ning Y., Venable S.F., Pereira-Smith O.M., Smith J.R. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp. Cell. Res. 211, 90-98.
-
(1994)
Exp. Cell. Res.
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
10
-
-
0028220204
-
p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest
-
Dulic V., Kaumann W.K., Wilson S.J., Tlsty T.D., Lees E., Harper J.W., Elledge S.J., Reed S.I. 1994. p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest. Cell. 76, 1013-1023.
-
(1994)
Cell
, vol.76
, pp. 1013-1023
-
-
Dulic, V.1
Kaumann, W.K.2
Wilson, S.J.3
Tlsty, T.D.4
Lees, E.5
Harper, J.W.6
Elledge, S.J.7
Reed, S.I.8
-
11
-
-
0028294605
-
WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis
-
El-Deiry W.S., Harper J.W., O'Connor P.M. et al. 1994. WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis. Cancer Res. 54, 1169-1174.
-
(1994)
Cancer Res.
, vol.54
, pp. 1169-1174
-
-
El-Deiry, W.S.1
Harper, J.W.2
O'Connor, P.M.3
-
12
-
-
0029662315
-
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity
-
Kriwacki R.W., Hengst L., Tennant L., Reed S.I., Wright P.E. 1996. Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: Conformational disorder mediates binding diversity. Proc. Natl. Acad. Sci. USA. 93, 11504-11509.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 11504-11509
-
-
Kriwacki, R.W.1
Hengst, L.2
Tennant, L.3
Reed, S.I.4
Wright, P.E.5
-
13
-
-
0028988158
-
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
-
Lee M.H., Reynisdottir I., Massague J. 1995. Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev. 9, 639-649.
-
(1995)
Genes Dev.
, vol.9
, pp. 639-649
-
-
Lee, M.H.1
Reynisdottir, I.2
Massague, J.3
-
14
-
-
0028899480
-
Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA
-
Chen J., Jackson P.K., Kirschner M.W., Dutta A. 1995. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature. 374, 386-388.
-
(1995)
Nature
, vol.374
, pp. 386-388
-
-
Chen, J.1
Jackson, P.K.2
Kirschner, M.W.3
Dutta, A.4
-
16
-
-
0028895385
-
Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1
-
Nakanishi M., Robertorye R.S., Adami G.R., Pereira-Smith O.M., Smith J.R. 1995. Identification of the active region of the DNA synthesis inhibitory gene p21Sdi1/CIP1/WAF1. EMBO J. 14, 555-563.
-
(1995)
EMBO J.
, vol.14
, pp. 555-563
-
-
Nakanishi, M.1
Robertorye, R.S.2
Adami, G.R.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
17
-
-
0029021714
-
Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor
-
Goubin E., Ducommun B. 1995. Identification of binding domains on the p21Cip1 cyclin-dependent kinase inhibitor. Oncogene. 10, 2281-2287.
-
(1995)
Oncogene
, vol.10
, pp. 2281-2287
-
-
Goubin, E.1
Ducommun, B.2
-
19
-
-
0032556952
-
p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells
-
Cayrol C., Knibiehler M., Ducommun B. 1998. p21 binding to PCNA causes G1 and G2 cell cycle arrest in p53-deficient cells. Oncogene. 16, 311-320.
-
(1998)
Oncogene
, vol.16
, pp. 311-320
-
-
Cayrol, C.1
Knibiehler, M.2
Ducommun, B.3
-
20
-
-
0000408538
-
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells
-
Park J.A., Kim K.W., Kim S.I., Lee S.K. 1998. Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells. Eur. J. Biochem. 257, 242-248.
-
(1998)
Eur. J. Biochem.
, vol.257
, pp. 242-248
-
-
Park, J.A.1
Kim, K.W.2
Kim, S.I.3
Lee, S.K.4
-
21
-
-
0032539602
-
Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen
-
Watanabe H., Pan Z.-Q., Schreiber-Agus N., DePinho R.A., Hurwitz J., Xiong Y. 1998. Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen. Proc. Natl. Acad. Sci. USA. 95, 1392-1397.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 1392-1397
-
-
Watanabe, H.1
Pan, Z.-Q.2
Schreiber-Agus, N.3
DePinho, R.A.4
Hurwitz, J.5
Xiong, Y.6
-
22
-
-
0031045565
-
PCNA: Structure, functions and interactions
-
Kleman Z. 1997. PCNA: structure, functions and interactions. Oncogene. 14, 629-640.
-
(1997)
Oncogene
, vol.14
, pp. 629-640
-
-
Kleman, Z.1
-
23
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
Waga S., Hannon G.J., Beach D., Stillman B. 1994. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature. 369, 574-578.
-
(1994)
Nature
, vol.369
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
24
-
-
0030743399
-
WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases
-
Ogrizko V.V., Wong P., Howard B.H. 1997. WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol. Cell. Biol. 17, 4877-4882.
-
(1997)
Mol. Cell. Biol.
, vol.17
, pp. 4877-4882
-
-
Ogrizko, V.V.1
Wong, P.2
Howard, B.H.3
-
25
-
-
0027440552
-
Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes
-
Zhang H., Xiong Y., Beach D. 1993. Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Oncogene. 4, 897-906.
-
(1993)
Oncogene
, vol.4
, pp. 897-906
-
-
Zhang, H.1
Xiong, Y.2
Beach, D.3
-
27
-
-
0036830109
-
Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: Delineation and structural insight into their interactions with cyclin A
-
Zheleva D.I., Mclnnes C., Gavine A.L., Zhelev N.Z., Fischer P.M., Lane D.P. 2002. Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A. J. Pept. Res. 60, 257-270.
-
(2002)
J. Pept. Res.
, vol.60
, pp. 257-270
-
-
Zheleva, D.I.1
Mclnnes, C.2
Gavine, A.L.3
Zhelev, N.Z.4
Fischer, P.M.5
Lane, D.P.6
-
28
-
-
0028365708
-
Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21
-
Li Y., Jenkins C.W., Nichols M.A., Xiong Y. 1994. Cell cycle expression and p53 regulation of the cyclin-dependent kinase inhibitor p21. Oncogene. 9, 2261-2268.
-
(1994)
Oncogene
, vol.9
, pp. 2261-2268
-
-
Li, Y.1
Jenkins, C.W.2
Nichols, M.A.3
Xiong, Y.4
-
30
-
-
0034649414
-
Stoichiometry of cyclin A-cyclin-dependent kinase 2 inhibition by p21Cip1/Waf1
-
Adkins J.N., Lumb K.J. 2002. Stoichiometry of cyclin A-cyclin-dependent kinase 2 inhibition by p21Cip1/Waf1. Biochemistry, 39, 13925-13930.
-
(2002)
Biochemistry
, vol.39
, pp. 13925-13930
-
-
Adkins, J.N.1
Lumb, K.J.2
-
31
-
-
0029016275
-
Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21
-
Podust V.N., Podust L.M., Goubin E., Ducommun B., Hubscher U. 1995. Mechanism of inhibition of proliferating cell nuclear antigen-dependent DNA synthesis by the cyclin-dependent kinase inhibitor p21. Biochemistry. 34, 8869-8875.
-
(1995)
Biochemistry
, vol.34
, pp. 8869-8875
-
-
Podust, V.N.1
Podust, L.M.2
Goubin, E.3
Ducommun, B.4
Hubscher, U.5
-
33
-
-
0030845187
-
Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4
-
Blain S.W., Montalvo E., Massague J. 1997. Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4. J. Biol. Chem. 272, 25863-25872.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25863-25872
-
-
Blain, S.W.1
Montalvo, E.2
Massague, J.3
-
34
-
-
0028169236
-
p21-containing cyclin kinases exist in both active and inactive states
-
Zhang H., Hannon G.J., Beach D. 1994. p21-containing cyclin kinases exist in both active and inactive states. Genes Dev. 8, 1750-1758.
-
(1994)
Genes Dev.
, vol.8
, pp. 1750-1758
-
-
Zhang, H.1
Hannon, G.J.2
Beach, D.3
-
35
-
-
9044232147
-
Formation of p27-CDK complexes during the human mitotic cell cycle
-
Soos T.J., Kiyokawa H., Yan J.S., Rubin M.S., Giordano A., DeBlasio A., Bottega S., Wong B., Mendelsohn J., Koff A. 1996. Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth & Differentiation. 17, 135-146.
-
(1996)
Cell Growth & Differentiation
, vol.17
, pp. 135-146
-
-
Soos, T.J.1
Kiyokawa, H.2
Yan, J.S.3
Rubin, M.S.4
Giordano, A.5
DeBlasio, A.6
Bottega, S.7
Wong, B.8
Mendelsohn, J.9
Koff, A.10
-
36
-
-
0028988585
-
Inhibitors of mammalian G1 cyclin-dependent kinases
-
Sherr C., Roberts J.M. 1995. Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev. 9, 1149-1163.
-
(1995)
Genes Dev.
, vol.9
, pp. 1149-1163
-
-
Sherr, C.1
Roberts, J.M.2
-
37
-
-
0030973878
-
New functional activities for the p21 family of CDK inhibitors
-
LaBaer J., Garrett M.D., Stevenson L.F., Slingerland J.M., Sandhu C., Chou H.S., Fattaey A., Harlow E. 1997. New functional activities for the p21 family of CDK inhibitors. Genes Dev. 11, 847-862.
-
(1997)
Genes Dev.
, vol.11
, pp. 847-862
-
-
LaBaer, J.1
Garrett, M.D.2
Stevenson, L.F.3
Slingerland, J.M.4
Sandhu, C.5
Chou, H.S.6
Fattaey, A.7
Harlow, E.8
-
38
-
-
0029097759
-
Radiation-induced cell cycle arrest compromised by p21 deficiency
-
Brugarolas J., Chandrasekaran C., Gordon J.I., Jacks T., Hannon G.J. 1995. Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature. 377, 557.
-
(1995)
Nature
, vol.377
, pp. 557
-
-
Brugarolas, J.1
Chandrasekaran, C.2
Gordon, J.I.3
Jacks, T.4
Hannon, G.J.5
-
39
-
-
0028978183
-
Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control
-
Deng C., Zhang P., Harper J.W., Elledge S.J., Leder P. 1995. Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control. Cell. 82, 675-684.
-
(1995)
Cell
, vol.82
, pp. 675-684
-
-
Deng, C.1
Zhang, P.2
Harper, J.W.3
Elledge, S.J.4
Leder, P.5
-
40
-
-
0033559264
-
The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts
-
Cheng M., Olivier P., Diehl J.A., Fero M., Roussel M.F., Roberts J.M., Sherr C.J. 1999. The p21(Cip1) and p27(Kip1) CDK 'inhibitors' are essential activators of cyclin D-dependent kinases in murine fibroblasts. EMBO J. 18, 1571-1583.
-
(1999)
EMBO J.
, vol.18
, pp. 1571-1583
-
-
Cheng, M.1
Olivier, P.2
Diehl, J.A.3
Fero, M.4
Roussel, M.F.5
Roberts, J.M.6
Sherr, C.J.7
-
41
-
-
0030614715
-
The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2
-
Reynisdottir I., Massague J. 1997. The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2. Genes Dev. 11, 492-503.
-
(1997)
Genes Dev.
, vol.11
, pp. 492-503
-
-
Reynisdottir, I.1
Massague, J.2
-
43
-
-
0032511893
-
Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21
-
Cayrol C., Ducommun B. 1998. Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21. Oncogene. 17, 2437-2444.
-
(1998)
Oncogene
, vol.17
, pp. 2437-2444
-
-
Cayrol, C.1
Ducommun, B.2
-
44
-
-
0030925231
-
Cyclin E-CDK2 is a regulator of p27Kip1
-
Sheaff R.J., Groudine M., Gordon M., Roberts J.M., Clurman B.E. 1997. Cyclin E-CDK2 is a regulator of p27Kip1. Genes Dev. 11, 1464-1478.
-
(1997)
Genes Dev.
, vol.11
, pp. 1464-1478
-
-
Sheaff, R.J.1
Groudine, M.2
Gordon, M.3
Roberts, J.M.4
Clurman, B.E.5
-
45
-
-
0030847760
-
Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27
-
Vlach J., Hennecke S., Amati B. 1997. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27. EMBO J. 16, 5334-5344.
-
(1997)
EMBO J.
, vol.16
, pp. 5334-5344
-
-
Vlach, J.1
Hennecke, S.2
Amati, B.3
-
46
-
-
0034646679
-
Reversible phosphorylation at the C-terminal regulatory domain of p21Waf1/Cip1 modulates proliferating cell nuclear antigen binding
-
Scott M.T., Morrice N., Ball K.L. 2000. Reversible phosphorylation at the C-terminal regulatory domain of p21Waf1/Cip1 modulates proliferating cell nuclear antigen binding. J. Biol. Chem. 275, 11529-11537.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 11529-11537
-
-
Scott, M.T.1
Morrice, N.2
Ball, K.L.3
-
47
-
-
0034649479
-
PKCη associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes
-
Kashiwagi M., Ohba M., Watanabe H., Ishino K., Kasahara K., Sanai Y., Taya Y., Kuroki T. 2000. PKCη associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes. Oncogene. 19, 6334-6341.
-
(2000)
Oncogene
, vol.19
, pp. 6334-6341
-
-
Kashiwagi, M.1
Ohba, M.2
Watanabe, H.3
Ishino, K.4
Kasahara, K.5
Sanai, Y.6
Taya, Y.7
Kuroki, T.8
-
48
-
-
0032752063
-
Cellular survival: A play in three Akts
-
Datta S.R., Brunet A., Greenberg M.E. 1999. Cellular survival: a play in three Akts. Genes Dev. 13, 2905-2927.
-
(1999)
Genes Dev.
, vol.13
, pp. 2905-2927
-
-
Datta, S.R.1
Brunet, A.2
Greenberg, M.E.3
-
49
-
-
0029160069
-
Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
-
Burgering B.M., Coffer P.J. 1995. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature. 376, 599-602.
-
(1995)
Nature
, vol.376
, pp. 599-602
-
-
Burgering, B.M.1
Coffer, P.J.2
-
50
-
-
0034745353
-
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
-
Zhou B.P., Liao Y., Xia W., Spohn B., Lee M.H., Hung M.C. 2001. Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat. Cell. Biol. 3, 245-252.
-
(2001)
Nat. Cell. Biol.
, vol.3
, pp. 245-252
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Spohn, B.4
Lee, M.H.5
Hung, M.C.6
-
51
-
-
0036312303
-
Novel targets of Akt, p21(Cip1/WAF1), and MDM2
-
Zhou B.P., Hung M.C. 2002. Novel targets of Akt, p21(Cip1/WAF1), and MDM2. Semin. Oncol. 29 (3 Suppl 11), 62-70.
-
(2002)
Semin. Oncol.
, vol.29
, Issue.3 SUPPL. 11
, pp. 62-70
-
-
Zhou, B.P.1
Hung, M.C.2
-
52
-
-
0034941567
-
Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells
-
Rossig L., Jadidi A.S., Urbich C., Badorff C., Zeiher A.M., Dimmeler S. 2001. Akt-dependent phosphorylation of p21(Cip1) regulates PCNA binding and proliferation of endothelial cells. Mol. Cell. Biol. 21, 5644-5657.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
53
-
-
0037192852
-
AKT/PKB Phosphorylation of p21Cip/Waf1 enhances protein stability of p21Cip/Waf1 and promotes cell survival
-
Li Y., Dowbenko D., Lasky L.A. 2002. AKT/PKB Phosphorylation of p21Cip/Waf1 enhances protein stability of p21Cip/Waf1 and promotes cell survival. J. Biol. Chem. 277, 11352-11361.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11352-11361
-
-
Li, Y.1
Dowbenko, D.2
Lasky, L.A.3
-
54
-
-
0037155824
-
Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation
-
Rössig L., Badorff C., Holzmann Y., Zeiher A.M., Dimmeler S. 2002. Glycogen synthase kinase-3 couples AKT-dependent signaling to the regulation of p21Cip1 degradation. J. Biol. Chem. 277, 9684-9689.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9684-9689
-
-
Rössig, L.1
Badorff, C.2
Holzmann, Y.3
Zeiher, A.M.4
Dimmeler, S.5
-
55
-
-
33747362972
-
-
Russian source
-
-
-
-
56
-
-
0034632670
-
F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation
-
Malashicheva A.B., Kislyakova T.V., Aksenov N.D., Osipov K.A., Pospelov V.A. 2000. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation. Oncogene. 19, 3858-3865.
-
(2000)
Oncogene
, vol.19
, pp. 3858-3865
-
-
Malashicheva, A.B.1
Kislyakova, T.V.2
Aksenov, N.D.3
Osipov, K.A.4
Pospelov, V.A.5
-
57
-
-
0037121534
-
Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase
-
Wang Z., Bhattacharya N., Mixter P.F., Wei W., Sedivy J., Magnuson N.S. 2002. Phosphorylation of the cell cycle inhibitor p21Cip1/WAF1 by Pim-1 kinase. Biochim. Biophys. Acta. 1593, 45-55.
-
(2002)
Biochim. Biophys. Acta.
, vol.1593
, pp. 45-55
-
-
Wang, Z.1
Bhattacharya, N.2
Mixter, P.F.3
Wei, W.4
Sedivy, J.5
Magnuson, N.S.6
-
58
-
-
0037119470
-
The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation
-
Kim G.Y., Mercer S.E., Ewton D.Z., Van Z., Jin K., Friedman E. 2002. The stress-activated protein kinases p38 alpha and JNK1 stabilize p21(Cip1) by phosphorylation. J. Biol. Chem. 277, 29792-29802.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 29792-29802
-
-
Kim, G.Y.1
Mercer, S.E.2
Ewton, D.Z.3
Van, Z.4
Jin, K.5
Friedman, E.6
-
59
-
-
0032585893
-
Waf1/Cip1 acts in synergy with bcl-2 to confer multidrug resistance in a camptothecin-selected human lung-cancer cell line
-
Waf1/Cip1 acts in synergy with bcl-2 to confer multidrug resistance in a camptothecin-selected human lung-cancer cell line. Int. J. Cancer. 83, 790-797.
-
(1999)
Int. J. Cancer
, vol.83
, pp. 790-797
-
-
Zhang, Y.1
Fujita, N.2
Tsuruo, T.3
-
60
-
-
0036045455
-
p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells
-
Martinez L.A., Yang J., Vazquez E.S., Rodriguez-Vargas M. del C., Olive M., Hsieh J.T., Logothetis C.J., Navone N.M. 2002. p21 modulates threshold of apoptosis induced by DNA-damage and growth factor withdrawal in prostate cancer cells. Carcinogenesis. 23, 1289-1296.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1289-1296
-
-
Martinez, L.A.1
Yang, J.2
Vazquez, E.S.3
Rodriguez-Vargas, M.D.C.4
Olive, M.5
Hsieh, J.T.6
Logothetis, C.J.7
Navone, N.M.8
-
61
-
-
0037427570
-
Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1)
-
Weiss R.H., Marshall D., Howard L., Corbacho A.M., Cheung A.T., Sawai E.T. 2003. Suppression of breast cancer growth and angiogenesis by an antisense oligodeoxynucleotide to p21(Waf1/Cip1). Cancer Lett. 189, 39-48.
-
(2003)
Cancer Lett.
, vol.189
, pp. 39-48
-
-
Weiss, R.H.1
Marshall, D.2
Howard, L.3
Corbacho, A.M.4
Cheung, A.T.5
Sawai, E.T.6
-
62
-
-
0032411879
-
Stress signals for apoptosis: Ceramide and c-Jun kinase
-
Basu S., Kolesnick R. 1998. Stress signals for apoptosis: ceramide and c-Jun kinase. Oncogene. 17, 3277-3285.
-
(1998)
Oncogene
, vol.17
, pp. 3277-3285
-
-
Basu, S.1
Kolesnick, R.2
-
63
-
-
0032054723
-
Signal transaction by the c-Jun N-terminal kinase (JNK) - From inflammation to development
-
Ip Y.T., Davis R.J. 1998. Signal transaction by the c-Jun N-terminal kinase (JNK) - from inflammation to development. Curr. Opin. Cell. Biol. 10, 205-219.
-
(1998)
Curr. Opin. Cell. Biol.
, vol.10
, pp. 205-219
-
-
Ip, Y.T.1
Davis, R.J.2
-
64
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H., Nishida E., Irie K., ten Dijke P., Saitoh M., Moriguchi T., Takagi M., Matsumoto K., Miyazono K., Gotoh Y. 1997. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science. 275, 90-94.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
65
-
-
0033104495
-
Cip1/WAF1 in monocytic differentiation
-
Cip1/WAF1 in monocytic differentiation. EMBO J. 18, 1223-1234.
-
(1999)
EMBO J.
, vol.18
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
Mizutani, S.7
-
66
-
-
0029957019
-
A non-enzymatic p21 protein inhibitor of stress-activated protein kinases
-
Shim J., Lee H., Park J., Kim H., Choi E.J. 1996. A non-enzymatic p21 protein inhibitor of stress-activated protein kinases. Nature. 381, 804-806.
-
(1996)
Nature
, vol.381
, pp. 804-806
-
-
Shim, J.1
Lee, H.2
Park, J.3
Kim, H.4
Choi, E.J.5
-
67
-
-
0034738420
-
WAF1/Cip1: More than a break to the cell cycle?
-
WAF1/Cip1: more than a break to the cell cycle? Biochim. Biophys. Acta. 1471, M43-M56.
-
(2000)
Biochim. Biophys. Acta.
, vol.1471
-
-
Dotto, P.G.1
-
68
-
-
0033280669
-
Biochemical pathways of caspase activation during apoptosis
-
Budihardjo I., Oliver H., Lutter M., Luo X., Wang X. 1999. Biochemical pathways of caspase activation during apoptosis. Annu. Rev. Cell Dev. Biol. 15, 269-290.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 269-290
-
-
Budihardjo, I.1
Oliver, H.2
Lutter, M.3
Luo, X.4
Wang, X.5
-
69
-
-
0033521925
-
Caspase 3 inactivation to suppress Fas-mediated apoptosis: Identification of binding domain with p21 and ILP and inactivation machinery by p21
-
Suzuki A., Tsutomi Y., Miura M., Akahane K. 1999. Caspase 3 inactivation to suppress Fas-mediated apoptosis: identification of binding domain with p21 and ILP and inactivation machinery by p21. Oncogene. 18, 1239-1244.
-
(1999)
Oncogene
, vol.18
, pp. 1239-1244
-
-
Suzuki, A.1
Tsutomi, Y.2
Miura, M.3
Akahane, K.4
-
70
-
-
0033894919
-
Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase a
-
Suzuki A., Kawano H., Hayashida M., Hayasaki Y., Tsutomi Y., Akahane K. 2000. Procaspase 3/p21 complex formation to resist fas-mediated cell death is initiated as a result of the phosphorylation of p21 by protein kinase A. Cell Death Differ. 7, 721-728.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 721-728
-
-
Suzuki, A.1
Kawano, H.2
Hayashida, M.3
Hayasaki, Y.4
Tsutomi, Y.5
Akahane, K.6
-
71
-
-
0032563286
-
Cip1/Waf1 by caspases is an early event during DNA damage-induced apoptosis
-
Cip1/Waf1 by Caspases Is an Early Event during DNA Damage-induced Apoptosis. J. Biol. Chem. 273, 19207-19212.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19207-19212
-
-
Gervais, J.L.M.1
Seth, P.2
Zhang, H.3
-
72
-
-
0033521889
-
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis
-
Zhang Y., Fujita N., Tsuruo T. 1999b. Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosis. Oncogene. 18, 1131-1138.
-
(1999)
Oncogene
, vol.18
, pp. 1131-1138
-
-
Zhang, Y.1
Fujita, N.2
Tsuruo, T.3
-
73
-
-
0030614969
-
Upregulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis
-
Duttaroy A., Qian J.F., Smith J.S., Wang E. 1997. Upregulated P21CIP1 expression is part of the regulation quantitatively controlling serum deprivation-induced apoptosis. J. Cell. Biochem. 64, 434-446.
-
(1997)
J. Cell. Biochem.
, vol.64
, pp. 434-446
-
-
Duttaroy, A.1
Qian, J.F.2
Smith, J.S.3
Wang, E.4
-
74
-
-
0036124768
-
Stat1-dependent, p53-independent expression of p21waf1 modulates oxysterol-induced apoptosis
-
Aerawal S., Agrawal M.L., Chatterjee-Kishore M., Stark G.R., Chisolm G.M. 2002. Stat1-Dependent, p53-Independent Expression of p21waf1 modulates Oxysterol-Induced Apoptosis. Mol. Cell. Biol. 22, 1981-1992.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 1981-1992
-
-
Aerawal, S.1
Agrawal, M.L.2
Chatterjee-Kishore, M.3
Stark, G.R.4
Chisolm, G.M.5
-
76
-
-
0037075228
-
p21B, a variant of p21Waf1/Cip1, is induced by the p53 family
-
Nozell S., Chen X. 2002. p21B, a variant of p21Waf1/Cip1, is induced by the p53 family. Oncogene. 21, 1285-1294.
-
(2002)
Oncogene
, vol.21
, pp. 1285-1294
-
-
Nozell, S.1
Chen, X.2
-
77
-
-
18144434084
-
Cip1 and is involved in the regulation of its nuclear localization
-
Cip1 and is involved in the regulation of its nuclear localization. J. Biol Chem. 274, 24445-24448.
-
(1999)
J. Biol Chem.
, vol.274
, pp. 24445-24448
-
-
Taules, M.1
Rodriguez-Vilarrupla, A.2
Ruis, E.3
Estanyol, J.M.4
Casanovas, O.5
Sacks, D.B.6
Perez-Paya, E.7
Bachs, O.8
Agell, N.9
-
78
-
-
0033598444
-
Control of E2F activity by p21Waf1/Cip1
-
Delavaine L., La Thangue N.B. 1999. Control of E2F activity by p21Waf1/Cip1. Oncogene. 18, 5381-5392.
-
(1999)
Oncogene
, vol.18
, pp. 5381-5392
-
-
Delavaine, L.1
La Thangue, N.B.2
-
79
-
-
0034616116
-
cip1/waf1/sdi1 in DNA replication and transcription
-
cip1/waf1/sdi1 in DNA Replication and Transcription. J. Biol. Chem. 275, 10477-10483.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10477-10483
-
-
Kitaura, H.1
Shinshi, M.2
Uchikoshi, Y.3
Ono, T.4
Tsurimoto, T.5
Yoshikawa, H.6
Iguchi-Ariga, S.M.M.7
Ariga, H.8
-
80
-
-
0032523239
-
Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control
-
Di Cunto F., Topley G., Calautti E., Hsiao J., Ong L., Seth P.K., Dotto G.P. 1998. Inhibitory function of p21Cip1/WAF1 in differentiation of primary mouse keratinocytes independent of cell cycle control. Science. 280, 1069-1072.
-
(1998)
Science
, vol.280
, pp. 1069-1072
-
-
Di Cunto, F.1
Topley, G.2
Calautti, E.3
Hsiao, J.4
Ong, L.5
Seth, P.K.6
Dotto, G.P.7
-
81
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng C.Y., Graves P.R., Thoma R.S., Wu Z., Shaw A.S., Piwnica-Worms H. 1997. Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science. 277, 1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
Piwnica-Worms, H.6
-
82
-
-
0027007963
-
Role of phosphorylation in p34cdc2 activation: Identification of an activating kinase
-
Solomon D.L., Lee T., Kirschner M.W. 1992. Role of phosphorylation in p34cdc2 activation: identification of an activating kinase. Mol. Biol. Cell. 3, 13-27.
-
(1992)
Mol. Biol. Cell
, vol.3
, pp. 13-27
-
-
Solomon, D.L.1
Lee, T.2
Kirschner, M.W.3
-
83
-
-
0026021668
-
Induction by ionizing radiation of the gadd45 gene in cultured human cells: Lack of mediation by protein kinase C
-
Papathanasiou M.A., Kerr N.C., Robbins J.H., McBride O.W., Alama I. Jr., Barrett S.F., Hickson I.D., Fornace Jr. 1991. Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. Mol. Cell. Biol. 11, 1009-1016.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 1009-1016
-
-
Papathanasiou, M.A.1
Kerr, N.C.2
Robbins, J.H.3
McBride, O.W.4
Alama Jr., I.5
Barrett, S.F.6
Hickson, I.D.7
Fornace, Jr.8
-
84
-
-
0032553485
-
2 arrest after DNA damage
-
2 arrest after DNA damage. Science. 282, 1497-1501.
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
Dutriaux, A.2
Lengauer, C.3
Waldman, T.4
Zhou, S.5
Brown, J.P.6
Sedivy, J.M.7
Kinzler, K.W.8
Vogelstein, B.9
-
85
-
-
0028793807
-
Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1
-
Kearsey J.M., Coates P.J., Prescott A.R., Warbrick E., Hall P.A. 1995. Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1. Oncogene. 11, 1675-1683.
-
(1995)
Oncogene
, vol.11
, pp. 1675-1683
-
-
Kearsey, J.M.1
Coates, P.J.2
Prescott, A.R.3
Warbrick, E.4
Hall, P.A.5
-
86
-
-
0029922537
-
The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1
-
Vairapandi M., Balliet A.G., Fornace A.J.Jr., Hoffman B., Lieberman D.A. 1996. The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1. Oncogene. 12, 2579-2594.
-
(1996)
Oncogene
, vol.12
, pp. 2579-2594
-
-
Vairapandi, M.1
Balliet, A.G.2
Fornace Jr., A.J.3
Hoffman, B.4
Lieberman, D.A.5
-
87
-
-
0034711210
-
2/M checkpoint
-
2/M Checkpoint. J. Biol. Chem. 275, 36892-36898.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36892-36898
-
-
Yang, Q.1
Manicone, A.2
Coursen, J.D.3
Linke, S.P.4
Nagashima, M.5
Forgues, M.6
Wang, X.W.7
-
88
-
-
0035914346
-
Oligomerization of human Gadd45a protein
-
Kovalsky O., Lung F.D., Roller P.P., Fornace A.J.Jr. 2001. Oligomerization of human Gadd45a protein. J. Biol. Chem. 276, 39330-39339.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 39330-39339
-
-
Kovalsky, O.1
Lung, F.D.2
Roller, P.P.3
Fornace Jr., A.J.4
-
91
-
-
0034613256
-
Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase
-
Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase. J. Biol. Chem. 275, 31145-31154.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 31145-31154
-
-
Ono, T.1
Kitaura, H.2
Ugai, H.3
Murata, T.4
Yokoyama, K.K.5
Iguchi-Ariga, S.M.M.6
Ariga, H.7
-
92
-
-
0033595810
-
Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1
-
Mitsui K., Matsumoto A., Ohtsuka S., Ohtsubo M., Yoshimura A. 1999. Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1. Biochem. Biophys. Res. Commun. 264, 457-464.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.264
, pp. 457-464
-
-
Mitsui, K.1
Matsumoto, A.2
Ohtsuka, S.3
Ohtsubo, M.4
Yoshimura, A.5
-
93
-
-
0030827303
-
Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein
-
Funk J.O., Waga S., Harry J.B., Espling E., Stillman B., Galloway D.A. 1997. Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes Dev. 11, 2090-2100.
-
(1997)
Genes Dev.
, vol.11
, pp. 2090-2100
-
-
Funk, J.O.1
Waga, S.2
Harry, J.B.3
Espling, E.4
Stillman, B.5
Galloway, D.A.6
-
94
-
-
0036787917
-
E7 abolishes raf-induced arrest via mislocalization of p21(Cip1)
-
Westbrook T.F., Nguyen D.X., Thrash B.R., McCance D.J. 2002. E7 abolishes raf-induced arrest via mislocalization of p21(Cip1). Mol. Cell. Biol. 22, 7041-7052.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7041-7052
-
-
Westbrook, T.F.1
Nguyen, D.X.2
Thrash, B.R.3
McCance, D.J.4
-
95
-
-
0033046766
-
The simian virus 40 small-t and large-T antigens jointly regulate cell cycle reentry in human fibroblasts
-
Porras A., Gaillard S., Rundell K. 1999. The simian virus 40 small-t and large-T antigens jointly regulate cell cycle reentry in human fibroblasts. J. Virol. 73, 3102-3107.
-
(1999)
J. Virol.
, vol.73
, pp. 3102-3107
-
-
Porras, A.1
Gaillard, S.2
Rundell, K.3
-
96
-
-
0035931856
-
RB regulates transcription of the p21/WAF1/CIP1 gene
-
Decesse J.T., Medjkane S., Datto M.B., Cremisi C.E. 2001. RB regulates transcription of the p21/WAF1/CIP1 gene. Oncogene. 20, 962-971.
-
(2001)
Oncogene
, vol.20
, pp. 962-971
-
-
Decesse, J.T.1
Medjkane, S.2
Datto, M.B.3
Cremisi, C.E.4
-
97
-
-
0030892906
-
Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region
-
Somasundaram R., El-Deiry W.S. 1997. Inhibition of p53-mediated transactivation and cell cycle arrest by E1A through its p300/CBP-interacting region. Oncogene. 14, 1047-1057.
-
(1997)
Oncogene
, vol.14
, pp. 1047-1057
-
-
Somasundaram, R.1
El-Deiry, W.S.2
-
98
-
-
0029863824
-
Adenovirus E1A proteins inhibit activation of transcription by p53
-
Steegenga W.T., van Laar T., Riteco N., Mandarino A., Shvarts A., van der Eb A., Jochemsen A.G. 1996. Adenovirus E1A proteins inhibit activation of transcription by p53. Mol. Cell. Biol. 16, 2101-2109.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 2101-2109
-
-
Steegenga, W.T.1
Van Laar, T.2
Riteco, N.3
Mandarino, A.4
Shvarts, A.5
Van Der Eb, A.6
Jochemsen, A.G.7
-
99
-
-
0029020945
-
Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation
-
Missero C., Calautti E., Eckner R., Chin J., Tsai L.H., Livingston D.M., Dotto G.P. 1995. Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc. Natl. Acad. Sci. USA. 92, 5451-5455.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 5451-5455
-
-
Missero, C.1
Calautti, E.2
Eckner, R.3
Chin, J.4
Tsai, L.H.5
Livingston, D.M.6
Dotto, G.P.7
-
100
-
-
33747349297
-
-
Russian source
-
-
-
-
101
-
-
0033533614
-
Deregulation of p53/p21Cip1/waf1 pathway contributes to polyploidy and apoptosis of E1A + cHa-ras transformed cells after γ-irradiation
-
Bulavin D.V., Tararova N.D., Aksenov N.D., Pospelov V.A., Pospelova T.V. 1999. Deregulation of p53/p21Cip1/waf1 pathway contributes to polyploidy and apoptosis of E1A + cHa-ras transformed cells after γ-irradiation. Oncogene. 18, 5611-5619.
-
(1999)
Oncogene
, vol.18
, pp. 5611-5619
-
-
Bulavin, D.V.1
Tararova, N.D.2
Aksenov, N.D.3
Pospelov, V.A.4
Pospelova, T.V.5
-
103
-
-
0034801802
-
Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells
-
Chattopadhyay D., Ghosh M.K., Mal A., Harter M.L. 2001. Inactivation of p21 by E1A leads to the induction of apoptosis in DNA-damaged cells. J. Virol. 75, 9844-9856.
-
(2001)
J. Virol.
, vol.75
, pp. 9844-9856
-
-
Chattopadhyay, D.1
Ghosh, M.K.2
Mal, A.3
Harter, M.L.4
-
105
-
-
0034678364
-
p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells
-
Mal A., Chattopadhyay D., Ghosh M.K., Poon R.Y., Hunter T., Harter M.L. 2000. p21 and retinoblastoma protein control the absence of DNA replication in terminally differentiated muscle cells. Cell Biol. 149, 281-292.
-
(2000)
Cell Biol.
, vol.149
, pp. 281-292
-
-
Mal, A.1
Chattopadhyay, D.2
Ghosh, M.K.3
Poon, R.Y.4
Hunter, T.5
Harter, M.L.6
-
106
-
-
0029876717
-
Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes
-
Mal A., Piotrkowski A., Harter M.L. 1996. Cyclin-dependent kinases phosphorylate the adenovirus E1A protein, enhancing its ability to bind pRb and disrupt pRb-E2F complexes. J. Virol. 70, 2911-2921.
-
(1996)
J. Virol.
, vol.70
, pp. 2911-2921
-
-
Mal, A.1
Piotrkowski, A.2
Harter, M.L.3
-
107
-
-
0032551722
-
Interaction of p27 with E1A and its effect on CDK kinase activity
-
Nomura H., Sawada Y., Ohtaki S. 1998. Interaction of p27 with E1A and its effect on CDK kinase activity. Biochem. Biophys. Res. Commun. 248, 228-234.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.248
, pp. 228-234
-
-
Nomura, H.1
Sawada, Y.2
Ohtaki, S.3
-
108
-
-
0030909148
-
Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes
-
Perez-Roger I., Solomon D.L., Sewing A., Land H. 1997. Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes. Oncogene. 14, 2373-2381.
-
(1997)
Oncogene
, vol.14
, pp. 2373-2381
-
-
Perez-Roger, I.1
Solomon, D.L.2
Sewing, A.3
Land, H.4
-
109
-
-
0029822745
-
Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc
-
Vlach J., Hennecke S., Alevizopoulos K., Conti D., Amati B. 1996. Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc. EMBO J. 15, 6595-6604.
-
(1996)
EMBO J.
, vol.15
, pp. 6595-6604
-
-
Vlach, J.1
Hennecke, S.2
Alevizopoulos, K.3
Conti, D.4
Amati, B.5
-
110
-
-
0035754080
-
To cyle or not to cycle: A critical decision in cancer
-
Malumbres M.B.M. 2001. To cyle or not to cycle: A critical decision in cancer. Nature Rev. Cancer. 1, 222-231.
-
(2001)
Nature Rev. Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.B.M.1
-
111
-
-
0027422247
-
The pathway to signal achievement
-
Egan S.E., Weinberg R.A. 1993. The pathway to signal achievement. Nature. 365, 781-783.
-
(1993)
Nature
, vol.365
, pp. 781-783
-
-
Egan, S.E.1
Weinberg, R.A.2
-
112
-
-
0032493812
-
Increasing complexity of the ras signaling pathway
-
Voitek A.B., Der C.J. 1998. Increasing Complexity of the Ras Signaling Pathway. J. Biol. Chem. 273, 19925-19928.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19925-19928
-
-
Voitek, A.B.1
Der, C.J.2
-
114
-
-
0033630808
-
Role of pRB dephosphorylation in cell cycle regulation
-
Tamrakar S., Rubin E., Ludlow J.W. 2000. Role of pRB dephosphorylation in cell cycle regulation. Front. Biosc. 5, d121-d137.
-
(2000)
Front. Biosc.
, vol.5
-
-
Tamrakar, S.1
Rubin, E.2
Ludlow, J.W.3
-
115
-
-
0032533225
-
Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
-
Diehl J.A., Cheng M., Roussel M.F., Sherr C. 1998. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev. 12, 3499-3511.
-
(1998)
Genes Dev.
, vol.12
, pp. 3499-3511
-
-
Diehl, J.A.1
Cheng, M.2
Roussel, M.F.3
Sherr, C.4
-
116
-
-
85078504862
-
Induction of transcription through the p300 CRD1 motif by p21(WAF1/CIP1) is core promoter specific and cyclin dependent kinase independent
-
Gregory D.J., Garcia-Wilson E., Poole J.C., Snowden A.W., Roninson I.E., Perkins N.D. 2002. Induction of Transcription through the p300 CRD1 Motif by p21(WAF1/CIP1) Is Core Promoter Specific and Cyclin Dependent Kinase Independent. Cell Cycle. 1, 343-350.
-
(2002)
Cell Cycle
, vol.1
, pp. 343-350
-
-
Gregory, D.J.1
Garcia-Wilson, E.2
Poole, J.C.3
Snowden, A.W.4
Roninson, I.E.5
Perkins, N.D.6
-
117
-
-
0036048524
-
Not just a CDK inhibitor: Regulation of transcription by p21(WAF1/CIP1/SDI1)
-
Perkins N.D. 2002. Not just a CDK inhibitor: regulation of transcription by p21(WAF1/CIP1/SDI1). Cell Cycle. 1, 39-41.
-
(2002)
Cell Cycle
, vol.1
, pp. 39-41
-
-
Perkins, N.D.1
-
118
-
-
0036047982
-
Identification of promoter elements responsible for transcriptional inhibition of polo-like kinase 1 and topoisomerase IIalpha genes by p21(WAFl/CIP1/SDI1)
-
Zhu H., Chang B.D., Uchiumi T., Roninson I.B. 2002. Identification of promoter elements responsible for transcriptional inhibition of polo-like kinase 1 and topoisomerase IIalpha genes by p21(WAFl/CIP1/SDI1). Cell Cycle. 1, 59-66.
-
(2002)
Cell Cycle
, vol.1
, pp. 59-66
-
-
Zhu, H.1
Chang, B.D.2
Uchiumi, T.3
Roninson, I.B.4
-
119
-
-
0036696411
-
P53 pathways involving G2 checkpoint regulators and the role of their subcellular localisation
-
Winters Z.E. 2002. P53 pathways involving G2 checkpoint regulators and the role of their subcellular localisation. J. R Coll. Surg. Edinb. 47, 591-598.
-
(2002)
J. R Coll. Surg. Edinb.
, vol.47
, pp. 591-598
-
-
Winters, Z.E.1
-
120
-
-
0033287224
-
p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E
-
Nargi J.L., Ratan R.R., Griffin D.E. 1999. p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E. Neoplasi. 1, 544-556.
-
(1999)
Neoplasi.
, vol.1
, pp. 544-556
-
-
Nargi, J.L.1
Ratan, R.R.2
Griffin, D.E.3
-
121
-
-
0036566326
-
Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence
-
Macip S., Igarashi M., Fang L., Chen A., Pan Z.Q., Lee S.W., Aaronson S.A. 2002. Inhibition of p21-mediated ROS accumulation can rescue p21-induced senescence. EMBO J. 21, 2180-2188.
-
(2002)
EMBO J.
, vol.21
, pp. 2180-2188
-
-
Macip, S.1
Igarashi, M.2
Fang, L.3
Chen, A.4
Pan, Z.Q.5
Lee, S.W.6
Aaronson, S.A.7
-
122
-
-
0034769218
-
p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity
-
Helt C.E., Rancourt R.C., Staversky R.J., O'Reilly M.A. 2001. p53-dependent induction of p21(Cip1/WAF1/Sdi1) protects against oxygen-induced toxicity. Toxicol. Sci. 63, 214-222.
-
(2001)
Toxicol. Sci.
, vol.63
, pp. 214-222
-
-
Helt, C.E.1
Rancourt, R.C.2
Staversky, R.J.3
O'Reilly, M.A.4
-
123
-
-
0036396193
-
Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species
-
Xie S., Wang Q., Luo L., Ruan Q., Liu T., Jhanwar-Uniyal M., Darzynkiewicz Z., Traganos F., Dai W. 2002. Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species. J. Interferon Cytokine Res. 22, 957-963.
-
(2002)
J. Interferon Cytokine Res.
, vol.22
, pp. 957-963
-
-
Xie, S.1
Wang, Q.2
Luo, L.3
Ruan, Q.4
Liu, T.5
Jhanwar-Uniyal, M.6
Darzynkiewicz, Z.7
Traganos, F.8
Dai, W.9
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