WAF1 retards S-phase progression primarily by inhibition of cyclin- dependent kinases

Molecular and Cellular Biology

Volumn 17, Issue 8, 1997, Pages 4877-4882

  Ogryzko, Vasily V ^a   Wong, Patricia ^a   Howard, Bruce H ^a  

^a EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN DEPENDENT KINASE; CYCLIN E; CYCLINE; GENE PRODUCT; PROTEIN P21; VIRUS SMALL T ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN DOMAIN;

MAMMALIA; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0030743399     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.17.8.4877     Document Type: Article

References (40)

1. Adams, P. D., W. R. Sellers, S. K. Sharma, A. D. Wu, C. M. Nalin, and W. G. kaelin, Jr. 1996. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors. Mol. Cell. Biol. 16:6623-6633.
2. Bikel, I., X. Montano, M. E. Agha, M. Brown, M. McCormack, J. Boltax, and D. M. Livingston. 1987. SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Cell 48:321-330.
3. Chen, J., P. Jackson, M. Kirschner, and A. Dutta. 1995. Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA. Nature 374:386-388.
4. CIPI. Mol. Cell. Biol. 16:4673-4682.
5. Coverley, D., and R. Laskey. 1994. Regulation of eukaryotic DNA replication. Annu. Rev. Biochem. 63:745-776.
6. EI-Deiry, W. S., T. Tokino, V. E. Velculescu, D. B. Levy, R. Parsons, J. M. Trent, D. Lin, W. E. Mercer, K. W. Kinzler, and B. Vogelstein. 1993. WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825.
7. Epstein, C., and F. Cross. 1992. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev. 6:1695-1706.
8. Fang, F., and J. Newport. 1991. Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes. Cell 66:731-742.
9. Feilotter, H., C. Lingner, R. Rowley, and P. Young. 1992. Regulation of the G2-mitosis transition. Biochem. Cell Biol. 70:954-971.
10. Flores-Rozas, H., Z. Kelman, F. Dean, Z. Pan, J. Harper, S. Elledge, M. O'Donnell, and J. Hurwitz. 1994. Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme. Proc. Natl. Acad. Sci. USA 91:8655-8659.
11. Giordano, T., T. Howard, J. Coleman, K. Sakamoto, and B. Howard. 1991. Isolation of a population of transiently transfected quiescent and senescent cells by magnetic affinity cell sorting. Exp. Cell Res. 192:193-197.
12. Goldstein, S., C. M. Fordis, and B. H. Howard. 1989. Enhanced transfection efficiency and improved cell survival after electroporation of G2/M-synchronized cells and treatment with sodium butyrate. Nucleic Acids Res. 17:3959-3971.
13. Harper, J. W., G. R. Adami, N. Wei, K. Keyomarsi, and S. J. Elledge. 1993. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclindependent kinascs. Cell 75:805-816.
14. Heichman, K., and J. Roberts. 1994. Rules to replicate by. Cell 79:557-562.
15. Hinds, P. W., S. Mittnacht, V. Dulic, A. Arnold, S. I. Reed, and R. A. Weinberg. 1992. Regulation of retinoblastoma protein functions by ectopic expression of human cyclins. Cell 70:993-1006.
16. Hunter, T., and J. Pines. 1994. Cyclins and cancer 2: cyclin D and CDK inhibitors come of age. Cell 79:573-582.
17. Jaskulski, D., C. Gatti, S. Travail, B. Calabretta, and R. Baserga. 1988. Regulation of the proliferating cell nuclear antigen eyclin and thymidine kinase mRNA levels by growth factors. J. Biol. Chem. 263:10175-10179.
18. Lu, X., and D. Lane. 1993. Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? Cell 75:765-778.
19. Luo, Y., J. Hurwitz, and J. Massague. 1995. Cell-cycle inhibition by independent CDK and PCNA binding domains in p21 Cip1. Nature 375:159-161.
20. Martin, R. G., V. P. Setlow, C. A. Edwards, and D. Vembu. 1979. The roles of the simian virus 40 tumor antigens in transformation of Chinese hamster lung cells. Cell 17:635-643.
21. Mumby, M., and G. Walter. 1993. Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol. Rev. 73:673-699.
22. Noda, A., Y. Ning, S. F. Venable, O. M. Pereira-Smith, and J. R. Smith. 1994. Cloning of senescent cell-derived inhibitors of DNA synthesis usine an expression screen. Exp. Cell Res. 211:90-98.
23. Ogryzko, V. V., T. H. Hirai, C. E. Shin, and B. H. Howard. 1994. Dissociation of retinoblastoma gene protein hyperphosphorylation and commitment to enter S phase. J. Virol. 68:3724-3732.
24. 23a.Ogryzko, V. Unpublished data.
25. Pagano, M., R. Pepperkok, F. Verde, W. Ansorge, and G. Draetta. 1992. Cyclin A is required at two points in the human cell cycle. EMBO J. 11:961-971.
26. Peter, M., and I. Herskowitz. 1994. Joining the complex: cyclin-dependent kinase inhibitory proteins and the cell cycle. Cell 79:181-184.
27. Polyak, K., M. Lee, H. Erdjument-Bromage, A. Koff, J. Roberts, P. Tempst, and J. Massague. 1994. Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals. Cell 78:59-66.
28. 1 phase in rodent fibroblasts. Genes Dev. 7:1559-1571.
29. Ruediger, R., D. Roeckel, J. Fait, A. Bergqvist, G. Magnusson, and G. Walter. 1992. Identification of binding sites on the regulatory A subunit of protein phosphatase 2A for the catalytic C subunit and for tumor antigens of simian virus 40 and polyomavirus. Mol. Cell. Biol. 12:4872-4882.
30. Sakamoto, K., T. Howard, V. Ogryzko, N.-Z. Xu, C. C. Corsico, J. H. Jones, and B. H. Howard. 1993. Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. Oncogene 8:1887-1893.
31. Scheidtmann, K. H., M. C. Mumby, K. Rundell, and G. Walter. 1991 Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen. Mol. Cell. Biol. 11:1996-2003.
32. Schwob, E., and K. Nasmyth. 1993. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev. 7:1160-1175.
33. Sherr, C. 1994. G1 phase progression: cycling on cue. Cell 79:551-555.
34. Sontag, E., S. Fedorov, C. Kamibayashi, D. Robbins, M. Cobb, and M. Muraby. 1993. The interaction of SV40 small tumor antigen with protein phospbatase 2A stimulates the map kinase pathway and induces cell proliferation. Cell 75:887-897.
35. Strausfeld, U., M. Howell, R. Rempel, J. Mailer, T. Hunt, and J. Blow. 1994. Cip1 blocks the initiation of DNA replication in Xenopus extracts by inhibition of cyclin-dependent kinases. Curr. Biol. 4:876-883.
36. 1, is dependent on growth status. Oncogene 6:317-322.
37. Vindetoøv, L. L., I. J. Christensen, and N. I. Nissen. 1983. A detergent-trypsin method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry 3:323-327.
38. Waga, S., G. Hannon, D. Beach, and B. Stillman. 1994. The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578.
39. Xiong, Y., G. Hannon, H. Zhang, D. Cassa, R. Kobayashi, and D. Beach. 1993. p21 is a universal inhibitor of cyclin kinases. Nature 366:701-704.
40. Yang, S.-I., R. L. Lickteig, R. Estes, K. Rundell, G. Walter, and M. C. Mumby. 1991. Control of protein phosphatase 2A by simian virus 40 small-t antigen. Mol. Cell. Biol. 11:1988-1995.