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Volumn 15, Issue 23, 1996, Pages 6595-6604

Growth arrest by the cyclin-dependent kinase inhibitor p27(Kip)1 is abrogated by c-Myc

Author keywords

CDK; CKI; Cyclin; Myc; p27

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLINE; GENE PRODUCT; PROTEIN KINASE INHIBITOR; RETINOBLASTOMA PROTEIN; UBIQUITIN;

EID: 0029822745     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01050.x     Document Type: Article
Times cited : (300)

References (79)
  • 1
    • 0028910316 scopus 로고
    • Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor β1
    • Alexandrow, M.G., Kawabata, M., Aakre, M. and Moses, H.L. (1995) Overexpression of the c-Myc oncoprotein blocks the growth-inhibitory response but is required for the mitogenic effects of transforming growth factor β1. Proc. Natl Acad. Sci. USA, 92, 3239-3243.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3239-3243
    • Alexandrow, M.G.1    Kawabata, M.2    Aakre, M.3    Moses, H.L.4
  • 2
    • 0028084338 scopus 로고
    • Myc-Max-Mad: A transcription factor network controlling cell cycle progression, differentiation and death
    • Amati, B. and Land, H. (1994) Myc-Max-Mad: a transcription factor network controlling cell cycle progression, differentiation and death. Curr. Opin. Genet. Dev., 4, 102-108.
    • (1994) Curr. Opin. Genet. Dev. , vol.4 , pp. 102-108
    • Amati, B.1    Land, H.2
  • 3
    • 0026665523 scopus 로고
    • Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max
    • Amati, B., Dalton, S., Brooks, M.W., Littlewood, T.D., Evan, G.I. and Land, H. (1992) Transcriptional activation by the human c-Myc oncoprotein in yeast requires interaction with Max. Nature, 359, 423-426.
    • (1992) Nature , vol.359 , pp. 423-426
    • Amati, B.1    Dalton, S.2    Brooks, M.W.3    Littlewood, T.D.4    Evan, G.I.5    Land, H.6
  • 4
    • 0027533679 scopus 로고
    • Oncogenic activity of the c-Myc protein requires dimerization with Max
    • Amati, B., Brooks, M.W., Levy, N., Littlewood, T.D., Evan, G.I. and Land, H. (1993a) Oncogenic activity of the c-Myc protein requires dimerization with Max. Cell, 72, 233-245.
    • (1993) Cell , vol.72 , pp. 233-245
    • Amati, B.1    Brooks, M.W.2    Levy, N.3    Littlewood, T.D.4    Evan, G.I.5    Land, H.6
  • 5
    • 0027364326 scopus 로고
    • The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max
    • Amati, B., Littlewood, T.D., Evan, G.I. and Land, H. (1993b) The c-Myc protein induces cell cycle progression and apoptosis through dimerization with Max. EMBO J., 12, 5083-5087.
    • (1993) EMBO J. , vol.12 , pp. 5083-5087
    • Amati, B.1    Littlewood, T.D.2    Evan, G.I.3    Land, H.4
  • 7
    • 0028879873 scopus 로고
    • Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src
    • Barone, M.V. and Courtneidge, S.A. (1995) Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src. Nature, 378, 509-512.
    • (1995) Nature , vol.378 , pp. 509-512
    • Barone, M.V.1    Courtneidge, S.A.2
  • 8
    • 0029031349 scopus 로고
    • Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes
    • Beijersbergen, R.L., Carlee, L., Kerkhoven, R.M. and Bernards, R. (1995) Regulation of the retinoblastoma protein-related p107 by G1 cyclin complexes. Genes Dev., 9, 1340-1353.
    • (1995) Genes Dev. , vol.9 , pp. 1340-1353
    • Beijersbergen, R.L.1    Carlee, L.2    Kerkhoven, R.M.3    Bernards, R.4
  • 9
    • 0029957947 scopus 로고    scopus 로고
    • Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation
    • Clurman, B.E., Sheaff, R.J., Thress, K., Groudine, M. and Roberts, J.M. (1996) Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation. Genes Dev., 10, 1979-1990.
    • (1996) Genes Dev. , vol.10 , pp. 1979-1990
    • Clurman, B.E.1    Sheaff, R.J.2    Thress, K.3    Groudine, M.4    Roberts, J.M.5
  • 10
    • 0029664461 scopus 로고    scopus 로고
    • Requirement of p27(kip1) for restriction point control of the fibroblast cell cycle
    • Coats, S., Flanagan, W.M., Nourse, J. and Roberts, J.M. (1996) Requirement of p27(kip1) for restriction point control of the fibroblast cell cycle. Science, 272, 877-880.
    • (1996) Science , vol.272 , pp. 877-880
    • Coats, S.1    Flanagan, W.M.2    Nourse, J.3    Roberts, J.M.4
  • 11
    • 0029049577 scopus 로고
    • Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes
    • DeGregori, J., Kowalik, T. and Nevins, J.R. (1995) Cellular targets for activation by the E2F1 transcription factor include DNA synthesis- and G1/S-regulatory genes. Mol. Cell. Biol., 15, 4215-4224.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 4215-4224
    • DeGregori, J.1    Kowalik, T.2    Nevins, J.R.3
  • 12
    • 0029864934 scopus 로고    scopus 로고
    • Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc
    • Desbarats, L., Gaubatz, S. and Eilers, M. (1996) Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc. Genes Dev., 10, 447-460.
    • (1996) Genes Dev. , vol.10 , pp. 447-460
    • Desbarats, L.1    Gaubatz, S.2    Eilers, M.3
  • 13
    • 0026099022 scopus 로고
    • The MYC protein activates transcription of the α-prothymosin gene
    • Eilers, M., Schirm, S. and Bishop, J.M. (1991) The MYC protein activates transcription of the α-prothymosin gene. EMBO J., 10, 133-141.
    • (1991) EMBO J. , vol.10 , pp. 133-141
    • Eilers, M.1    Schirm, S.2    Bishop, J.M.3
  • 15
    • 15844384256 scopus 로고    scopus 로고
    • A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(kip1)-deficient mice
    • Fero, M.L. et al. (1996) A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(kip1)-deficient mice. Cell, 85, 733-744.
    • (1996) Cell , vol.85 , pp. 733-744
    • Fero, M.L.1
  • 16
    • 0028229732 scopus 로고
    • Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes
    • Firpo, E., Koff, A., Solomon, M.J. and Roberts, J.M. (1994) Inactivation of a Cdk2 inhibitor during interleukin 2-induced proliferation of human T lymphocytes. Mol. Cell. Biol., 14, 4889-4901.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4889-4901
    • Firpo, E.1    Koff, A.2    Solomon, M.J.3    Roberts, J.M.4
  • 17
    • 0029779280 scopus 로고    scopus 로고
    • Cdc25 cell-cycle phosphatase as a target of c-myc
    • Galaktionov, K., Chen, X. and Beach, D. (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature, 382, 511-517.
    • (1996) Nature , vol.382 , pp. 511-517
    • Galaktionov, K.1    Chen, X.2    Beach, D.3
  • 18
    • 0028582034 scopus 로고
    • Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
    • Guan, K.L., Jenkins, C.W., Li, Y., Nichols, M.A., Wu, X., O'Keefe, C.L., Matera, A.G. and Xiong, Y. (1994) Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev., 8, 2939-2952.
    • (1994) Genes Dev. , vol.8 , pp. 2939-2952
    • Guan, K.L.1    Jenkins, C.W.2    Li, Y.3    Nichols, M.A.4    Wu, X.5    O'Keefe, C.L.6    Matera, A.G.7    Xiong, Y.8
  • 19
    • 0028168242 scopus 로고
    • p15 INK4B is a potential effector of TGFβ-induced growth arrest
    • Hannon, G.J. and Beach, D. (1994) p15 INK4B is a potential effector of TGFβ-induced growth arrest. Nature, 371, 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 21
  • 22
    • 0028263811 scopus 로고
    • c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines
    • Harrington, E.A., Bennett, M.R., Fanidi, A. and Evan, G.I. (1994) c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines. EMBO J., 13, 3286-3295.
    • (1994) EMBO J. , vol.13 , pp. 3286-3295
    • Harrington, E.A.1    Bennett, M.R.2    Fanidi, A.3    Evan, G.I.4
  • 23
    • 0029670477 scopus 로고    scopus 로고
    • Translational control of p27Kip1 accumulation during the cell cycle
    • Hengst, L. and Reed, S.I. (1996) Translational control of p27Kip1 accumulation during the cell cycle. Science, 271, 1861-1864.
    • (1996) Science , vol.271 , pp. 1861-1864
    • Hengst, L.1    Reed, S.I.2
  • 25
    • 0029686266 scopus 로고    scopus 로고
    • Proteins of the Myc network: Essential regulators of cell growth and differentiation
    • Henriksson, M. and Lüscher, B. (1996) Proteins of the Myc network: essential regulators of cell growth and differentiation. Adv. Cancer Res., 68, 109-182.
    • (1996) Adv. Cancer Res. , vol.68 , pp. 109-182
    • Henriksson, M.1    Lüscher, B.2
  • 26
    • 0028866121 scopus 로고
    • Abrogation of p53-induced cell cycle arrest by c-Myc: Evidence for an inhibitor of p21WAF1/CIP1/SDI1
    • Hermeking, H., Funk, J.O., Reichert, M., Ellwart, J.W. and Eick, D. (1995) Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21WAF1/CIP1/SDI1. Oncogene, 11, 1409-1415.
    • (1995) Oncogene , vol.11 , pp. 1409-1415
    • Hermeking, H.1    Funk, J.O.2    Reichert, M.3    Ellwart, J.W.4    Eick, D.5
  • 27
    • 0029863840 scopus 로고    scopus 로고
    • Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in rb-deficient fibroblasts
    • Herrera, R.E., Sah, V.P., Williams, B.O., Makela, T.P., Weinberg, R.A. and Tyler, J. (1996) Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in rb-deficient fibroblasts. Mol. Cell. Biol., 16, 2402-2407.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2402-2407
    • Herrera, R.E.1    Sah, V.P.2    Williams, B.O.3    Makela, T.P.4    Weinberg, R.A.5    Tyler, J.6
  • 28
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6
    • Hirai, H., Roussel, M.F., Kato, J.Y., Ashmun, R.A. and Sherr, C.J. (1995) Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6. Mol. Cell. Biol., 15, 2672-2681.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.J.5
  • 30
    • 0025166030 scopus 로고
    • An amino-terminal c-myc domain required for neoplastic transformation activates transcription
    • Kato, G.J., Barrett, J., Villa, G.M. and Dang, C.V. (1990) An amino-terminal c-myc domain required for neoplastic transformation activates transcription. Mol. Cell. Biol., 10, 5914-5920.
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 5914-5920
    • Kato, G.J.1    Barrett, J.2    Villa, G.M.3    Dang, C.V.4
  • 31
    • 0027973043 scopus 로고
    • Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation
    • Kato, J.Y., Matsuoka, M., Polyak, K., Massague, J. and Sherr, C.J. (1994) Cyclic AMP-induced G1 phase arrest mediated by an inhibitor (p27Kip1) of cyclin-dependent kinase 4 activation. Cell, 79, 487-496.
    • (1994) Cell , vol.79 , pp. 487-496
    • Kato, J.Y.1    Matsuoka, M.2    Polyak, K.3    Massague, J.4    Sherr, C.J.5
  • 32
    • 0029007867 scopus 로고
    • Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies
    • Kawamata, N. et al. (1995) Molecular analysis of the cyclin-dependent kinase inhibitor gene p27/Kip1 in human malignancies. Cancer Res., 55, 2266-2269.
    • (1995) Cancer Res. , vol.55 , pp. 2266-2269
    • Kawamata, N.1
  • 33
    • 0028793807 scopus 로고
    • Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1
    • Kearsey, J.M., Coates, P.J., Prescott, A.R., Warbrick, E. and Hall, P.A. (1995) Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1. Oncogene, 11, 1675-1683.
    • (1995) Oncogene , vol.11 , pp. 1675-1683
    • Kearsey, J.M.1    Coates, P.J.2    Prescott, A.R.3    Warbrick, E.4    Hall, P.A.5
  • 34
    • 0021709745 scopus 로고
    • Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals
    • Keath, E.J., Caimi, P.G. and Cole, M.D. (1984) Fibroblast lines expressing activated c-myc oncogenes are tumorigenic in nude mice and syngeneic animals. Cell, 39, 339-348.
    • (1984) Cell , vol.39 , pp. 339-348
    • Keath, E.J.1    Caimi, P.G.2    Cole, M.D.3
  • 35
    • 15844415946 scopus 로고    scopus 로고
    • Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(kip1)
    • Kiyokawa, H. et al. (1996) Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(kip1). Cell, 85, 721-732.
    • (1996) Cell , vol.85 , pp. 721-732
    • Kiyokawa, H.1
  • 36
    • 0027135209 scopus 로고
    • The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E
    • Li, Y., Graham, C., Lacy, S., Duncan, A.M. and Whyte, P. (1993) The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E. Genes Dev., 7, 2366-2377.
    • (1993) Genes Dev. , vol.7 , pp. 2366-2377
    • Li, Y.1    Graham, C.2    Lacy, S.3    Duncan, A.M.4    Whyte, P.5
  • 37
    • 0029670376 scopus 로고    scopus 로고
    • Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells
    • Mal, A., Poon, R.Y.C., Howe, P.H., Toyoshima, H., Hunter, T. and Harter M.L. (1996) Inactivation of p27Kip1 by the viral E1A oncoprotein in TGFβ-treated cells. Nature, 380, 262-265.
    • (1996) Nature , vol.380 , pp. 262-265
    • Mal, A.1    Poon, R.Y.C.2    Howe, P.H.3    Toyoshima, H.4    Hunter, T.5    Harter, M.L.6
  • 39
    • 0029118035 scopus 로고
    • Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130
    • Mayol X., Garriga, J. and Grana, X. (1995) Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130. Oncogene, 11, 801-808.
    • (1995) Oncogene , vol.11 , pp. 801-808
    • Mayol, X.1    Garriga, J.2    Grana, X.3
  • 40
    • 0027405991 scopus 로고
    • The IL-2 receptor complex: Its structure, function, and target genes
    • Minami, Y., Kono, T., Miyazaki, T. and Taniguchi, T. (1993) The IL-2 receptor complex: its structure, function, and target genes. Annu. Rev. Immunol., 11, 245-268.
    • (1993) Annu. Rev. Immunol. , vol.11 , pp. 245-268
    • Minami, Y.1    Kono, T.2    Miyazaki, T.3    Taniguchi, T.4
  • 41
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan, D.O. (1995) Principles of CDK regulation. Nature, 374, 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 42
    • 0025352187 scopus 로고
    • Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
    • Morgenstern, J.P. and Land, H. (1990) Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res., 18, 3587-3596.
    • (1990) Nucleic Acids Res. , vol.18 , pp. 3587-3596
    • Morgenstern, J.P.1    Land, H.2
  • 44
    • 0028918028 scopus 로고
    • Transcriptional regulation during the mammalian cell cycle
    • Müller, R. (1995) Transcriptional regulation during the mammalian cell cycle. Trends Genet., 11, 173-178.
    • (1995) Trends Genet. , vol.11 , pp. 173-178
    • Müller, R.1
  • 45
    • 0030010591 scopus 로고    scopus 로고
    • Mice lacking p27(kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors
    • Nakayama, K., Ishida, N., Shirane, M., Inomata, A., Inoue, T., Shishido, N., Hori, I., Loh, D.Y. and Nakayama, K. (1996) Mice lacking p27(kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell, 85, 707-720.
    • (1996) Cell , vol.85 , pp. 707-720
    • Nakayama, K.1    Ishida, N.2    Shirane, M.3    Inomata, A.4    Inoue, T.5    Shishido, N.6    Hori, I.7    Loh, D.Y.8    Nakayama, K.9
  • 47
    • 0029024015 scopus 로고
    • Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27
    • Pagano, M., Tam, S.W., Theodoras, A.M., Beer, R.P., Del, S.G., Chau, V., Yew, P.R., Draetta, G.F. and Rolfe, M. (1995) Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27. Science, 269, 682-685.
    • (1995) Science , vol.269 , pp. 682-685
    • Pagano, M.1    Tam, S.W.2    Theodoras, A.M.3    Beer, R.P.4    Del, S.G.5    Chau, V.6    Yew, P.R.7    Draetta, G.F.8    Rolfe, M.9
  • 48
    • 0024473604 scopus 로고
    • G1 events and regulation of cell proliferation
    • Pardee, A.B. (1989) G1 events and regulation of cell proliferation. Science, 246, 603-608.
    • (1989) Science , vol.246 , pp. 603-608
    • Pardee, A.B.1
  • 49
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W.S., Nolan, G.P., Scott, M.L. and Baltimore, D. (1993) Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl Acad. Sci. USA, 90, 8392-8396.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 50
    • 0028986931 scopus 로고
    • Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias
    • Pietenpol, J.A. et al. (1995) Assignment of the human p27Kip1 gene to 12p13 and its analysis in leukemias. Cancer Res., 55, 1206-1210.
    • (1995) Cancer Res. , vol.55 , pp. 1206-1210
    • Pietenpol, J.A.1
  • 51
    • 0028179669 scopus 로고
    • p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest
    • Polyak, K., Kato, J.Y., Solomon, M.J., Sherr, C.J., Massague, J., Roberts, J.M. and Koff, A. (1994a) p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-β and contact inhibition to cell cycle arrest. Genes Dev., 8, 9-22.
    • (1994) Genes Dev. , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 52
    • 0028176483 scopus 로고
    • Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals
    • Polyak, K., Lee, M.H., Erdjument, B.H., Koff, A., Roberts, J.M., Tempst, P. and Massague, J. (1994b) Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals, Cell, 78, 59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.H.2    Erdjument, B.H.3    Koff, A.4    Roberts, J.M.5    Tempst, P.6    Massague, J.7
  • 53
    • 0028986932 scopus 로고
    • p27Kip1: Chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors
    • Ponce-Castaneda, M.V. et al. (1995) p27Kip1: chromosomal mapping to 12p12-12p13.1 and absence of mutations in human tumors. Cancer Res., 55, 1211-1214.
    • (1995) Cancer Res. , vol.55 , pp. 1211-1214
    • Ponce-Castaneda, M.V.1
  • 54
    • 0029145975 scopus 로고
    • Redistribution of the CDK inhibitor p27 between different cyclin-CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin and ultraviolet irradiation
    • Poon, R.Y.C., Toyoshima, H. and Hunter, T. (1995) Redistribution of the CDK inhibitor p27 between different cyclin-CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin and ultraviolet irradiation. Mol. Biol. Cell, 6, 1197-1213.
    • (1995) Mol. Biol. Cell , vol.6 , pp. 1197-1213
    • Poon, R.Y.C.1    Toyoshima, H.2    Hunter, T.3
  • 55
    • 0029119852 scopus 로고
    • Cloning and characterization of murine p16INK4a and p15INK4b genes
    • Quelle, D.E. et al. (1995) Cloning and characterization of murine p16INK4a and p15INK4b genes. Oncogene, 11, 635-645.
    • (1995) Oncogene , vol.11 , pp. 635-645
    • Quelle, D.E.1
  • 56
    • 0021998699 scopus 로고
    • Abrogation of Il-3 and Il-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes
    • Rapp, U.R., Cleveland, J.L., Brightman, K., Scott, A. and Ihle, J.N. (1985) Abrogation of Il-3 and Il-2 dependence by recombinant murine retroviruses expressing v-myc oncogenes. Nature, 317, 434-438.
    • (1985) Nature , vol.317 , pp. 434-438
    • Rapp, U.R.1    Cleveland, J.L.2    Brightman, K.3    Scott, A.4    Ihle, J.N.5
  • 57
    • 0028989154 scopus 로고
    • Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo
    • Renno, T., Hahne, M. and MacDonald, R. (1995) Proliferation is a prerequisite for bacterial superantigen-induced T cell apoptosis in vivo. J. Exp. Med., 181, 2283-2287.
    • (1995) J. Exp. Med. , vol.181 , pp. 2283-2287
    • Renno, T.1    Hahne, M.2    MacDonald, R.3
  • 58
    • 0029153609 scopus 로고
    • Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β
    • Reynisdottir, I., Polyak, K., Iavarone, A. and Massague, J. (1995) Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-β. Genes Dev., 9, 1831-1845.
    • (1995) Genes Dev. , vol.9 , pp. 1831-1845
    • Reynisdottir, I.1    Polyak, K.2    Iavarone, A.3    Massague, J.4
  • 59
    • 0025861901 scopus 로고
    • Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling
    • Roussel, M.F. Cleveland, J.L., Shurtleff, S.A. and Sherr, C.J. (1991) Myc rescue of a mutant CSF-1 receptor impaired in mitogenic signalling. Nature, 353, 361-363.
    • (1991) Nature , vol.353 , pp. 361-363
    • Roussel, M.F.1    Cleveland, J.L.2    Shurtleff, S.A.3    Sherr, C.J.4
  • 61
    • 0029888119 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis
    • Rudolph, B., Saffrich, R., Zwicker, J., Henglein, B., Müller, R., Ansorge, W. and Eilers, M. (1996) Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A, but not apoptosis. EMBO J., 15, 3065-3076.
    • (1996) EMBO J. , vol.15 , pp. 3065-3076
    • Rudolph, B.1    Saffrich, R.2    Zwicker, J.3    Henglein, B.4    Müller, R.5    Ansorge, W.6    Eilers, M.7
  • 63
    • 0027336491 scopus 로고
    • Mammalian G1 cyclins
    • Sherr, C.J. (1993) Mammalian G1 cyclins. Cell, 73, 1059-1065.
    • (1993) Cell , vol.73 , pp. 1059-1065
    • Sherr, C.J.1
  • 64
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr, C.J. (1994) G1 phase progression: cycling on cue. Cell, 79, 551-555.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 66
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclin-dependent kinases
    • Sherr, C.J. and Roberts, J.M. (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev., 9, 1149-1163.
    • (1995) Genes Dev. , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.M.2
  • 67
    • 0028227197 scopus 로고
    • A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells
    • Slingerland, J.M., Hengst, L., Pan, C.H., Alexander, D., Stampfer, M.R. and Reed, S.I. (1994) A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor β-arrested epithelial cells. Mol. Cell. Biol., 14, 3683-3694.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 3683-3694
    • Slingerland, J.M.1    Hengst, L.2    Pan, C.H.3    Alexander, D.4    Stampfer, M.R.5    Reed, S.I.6
  • 68
    • 9044232147 scopus 로고    scopus 로고
    • Formation of p27-CDK complexes during the human mitotic cell cycle
    • Soos, T.J. et al. (1996) Formation of p27-CDK complexes during the human mitotic cell cycle. Cell Growth Differ., 7, 135-146.
    • (1996) Cell Growth Differ. , vol.7 , pp. 135-146
    • Soos, T.J.1
  • 71
    • 0023116071 scopus 로고
    • Definition of regions in human c-myc that are involved in transformation and nuclear localization
    • Stone, J., de Lange, T., Ramsay, G., Jakobvits, E., Bishop, J.M., Varmus, H. and Lee, W. (1987) Definition of regions in human c-myc that are involved in transformation and nuclear localization. Mol. Cell. Biol., 7, 1697-1709.
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1697-1709
    • Stone, J.1    De Lange, T.2    Ramsay, G.3    Jakobvits, E.4    Bishop, J.M.5    Varmus, H.6    Lee, W.7
  • 72
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Toyoshima, H. and Hunter, T. (1994) p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell, 78, 67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Toyoshima, H.1    Hunter, T.2
  • 73
    • 0029922537 scopus 로고    scopus 로고
    • The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1
    • Vairapandi, M., Balliet, A.G., Fornace, A.J.J., Hoffman, B. and Liebermann, D.A. (1996) The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1. Oncogene, 12, 2579-2594.
    • (1996) Oncogene , vol.12 , pp. 2579-2594
    • Vairapandi, M.1    Balliet, A.G.2    Fornace, A.J.J.3    Hoffman, B.4    Liebermann, D.A.5
  • 74
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R.A. (1995) The retinoblastoma protein and cell cycle control. Cell, 81, 323-330.
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 75
    • 0029977751 scopus 로고    scopus 로고
    • E2F and cell proliferation: A world turned upside down
    • Weinberg, R.A. (1996) E2F and cell proliferation: a world turned upside down. Cell, 85, 457-459.
    • (1996) Cell , vol.85 , pp. 457-459
    • Weinberg, R.A.1
  • 76
    • 0029737650 scopus 로고    scopus 로고
    • Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E
    • Won, K.-A. and Reed, S.I. (1996) Activation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin E. EMBO J., 15, 4182-4193.
    • (1996) EMBO J. , vol.15 , pp. 4182-4193
    • Won, K.-A.1    Reed, S.I.2
  • 77
    • 0030015264 scopus 로고    scopus 로고
    • Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases
    • Xiao, Z.-X., Ginsberg, D., Ewen, M. and Livingston, D.M. (1996) Regulation of the retinoblastoma protein-related protein p107 by G1 cyclin-associated kinases. Proc. Natl Acad. Sci. USA, 93, 4633-4637.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 4633-4637
    • Xiao, Z.-X.1    Ginsberg, D.2    Ewen, M.3    Livingston, D.M.4
  • 79
    • 0028351565 scopus 로고
    • The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
    • Zhan, Q. et al. (1994) The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth. Mol. Cell. Biol., 14, 2361-2371.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2361-2371
    • Zhan, Q.1


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