Proteasome-dependent downregulation of p21Waf1/Cip1 induced by reactive oxygen species

Journal of Interferon and Cytokine Research

Volumn 22, Issue 9, 2002, Pages 957-963

  Xie, Suqing ^a   Wang, Qi ^a   Luo, Lu ^a   Ruan, Qin ^a   Liu, Tongyi ^a   Jhanwar Uniyal, Meena ^a   Darzynkiewicz, Zbigniew ^a   Traganos, Frank ^a   Dai, Wei ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; DNA; DOXORUBICIN; HYDROGEN PEROXIDE; LACTACYSTIN; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN P21; PROTEIN SYNTHESIS INHIBITOR; REACTIVE OXYGEN METABOLITE; RNA;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; FLUORESCENCE MICROSCOPY; GENOTOXICITY; HALF LIFE TIME; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS REGULATION;

ACETYLCYSTEINE; CELL LINE; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; CYCLOHEXIMIDE; CYSTEINE ENDOPEPTIDASES; DOXORUBICIN; FIBROBLASTS; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; LEUPEPTINS; MULTIENZYME COMPLEXES; NEOPLASM PROTEINS; OXIDATIVE STRESS; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SYNTHESIS INHIBITORS; REACTIVE OXYGEN SPECIES;

EID: 0036396193     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/10799900260286669     Document Type: Article

References (19)

1. Kurata, S. (2000). Selective activation of p38 MAPK cascade and mitotic arrest caused by low level oxidative stress. J. Biol. Chem. 275, 23413-23416.
2. (2)/M arrest dependent and independent pathways in gastric carcinoma cells. Cancer 92, 500-509.
3. Canman, C.E., Lim, D.S., Cimprich, K.A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M.B., and Siliciano, J.D. (1998). Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 28, 1677-1679.
4. Caspari, T. (2000). How to activate p53. Curr. Biol. 10, R315-R317.
5. Siliciano, J.D., Canman, C.E., Taya, Y., Sakaguchi, K., Appella, E., and Kastan, M.B. (1997). DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev. 11, 3471-3481.
6. Oda, K., Arakawa, H., Tanaka, T., Matsuda, K., Tanikawa, C., Mori, T., Nishimori, H., Tamai, K., Tokino, T., Nakamura, Y., and Taya, Y. (2000). p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53. Cell 102, 849-862.
7. Zhu, J., Zhang, S., Jiang, J., and Chen, X. (2000). Definition of the p53 functional domains necessary for inducing apoptosis. J. Biol. Chem. 275, 39927-39934.
8. Xie, S., Wang, Q., Wu, H., Cogswell, J., LU, L., Jhanwar-Uniyal, M., and Dai, W. (2001). Reactive oxygen species-induced phosphorylation of p53 on serine 20 is mediated in part by polo-like kinase-3. J. Biol. Chem. 276, 36194-36199.
9. Vogelstein, B., Lane, D., and Levine, A.J. (2000). Surfing the p53 network. Nature 408, 307-310.
10. Maki, C.G., and Howley, P.M. (1997). Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol. Cell. Biol. 17, 355-363.
11. Fukuchi, K., Maruyama, H., Takagi, Y., and Gomi, K. (1999). Direct proteasome inhibition by clasto-lactacystin beta-lactone permits the detection of ubiquitinated p21(waf1) in ML-1 cells. Biochim. Biophys. Acta 1451, 206-210.
12. Sheaff, R.J., Singer, J.D., Swanger, J., Smitherman, M., Roberts, J.M., and Clurman, B.E. (2000). Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination. Mol. Cell 5, 403-410.
13. Hirao, A., Kong, Y.Y., Matsuoka, S., Wakeham, A., Ruland, J., Yoshida, H., Liu, D., Elledge, S.J., and Mak, T.W. (2000). DNA damage-induced activation of p53 by the checkpoint kinase Chk2. Science 287, 1824-1827.
14. Chang, T.C., Chou, W.Y., and Chang, G.G. (2000). Protein oxidation and turnover. J. Biomed. Sci. 7, 357-363.
15. Davies, K.J. (2001). Degradation of oxidized proteins by the 20S proteasome. Biochimie 83, 301-310.
16. 2/M transition by p53. Oncogene 20, 1803-1815.
17. Nargi, J.L., Ratan, R.R., and Griffin, D.E. (1999). p53-independent inhibition of proliferation and p21(WAF1/Cip1)-modulated induction of cell death by the antioxidants N-acetylcysteine and vitamin E. Neoplasia 1, 544-556.
18. Yakes, F.M., and Van Houten, B. (1997). Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA 94, 514-519.
19. Lee, S.H., Oe, T., and Blair, I.A. (2002). 4,5-Epoxy-2(E)-decenal-induced formation of 1,N(6)-etheno-2′-deoxyadenosine and 1,N(2)-etheno-2′-deoxyguanosine adducts. Chem. Res. Toxicol. 15, 300-304.