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Volumn 1, Issue 6, 1999, Pages 544-556

p53-Independent Inhibition of Proliferation and p21Waf1/Cip1-Modulated Induction of Cell Death by the Antioxidants N-acetylcysteine and Vitamin E1

Author keywords

Apoptosis; Colorectal; N acetylcysteine; p21Waf1 Cip1; p53

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; PROTEIN P53; REACTIVE OXYGEN METABOLITE; RETINOBLASTOMA PROTEIN;

EID: 0033287224     PISSN: 15228002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (33)

References (92)
  • 1
    • 0031990918 scopus 로고    scopus 로고
    • Antioxidant supplements and colorectal cancer
    • Konings E, and Greenberg ER (1998). Antioxidant supplements and colorectal cancer. Nutrition 14, 245-247.
    • (1998) Nutrition , vol.14 , pp. 245-247
    • Konings, E.1    Greenberg, E.R.2
  • 2
    • 0030043446 scopus 로고    scopus 로고
    • Cancer statistics
    • Parker SL (1996). Cancer statistics. Ca-Cancer J Clin 46, 5-27.
    • (1996) Ca-Cancer J Clin , vol.46 , pp. 5-27
    • Parker, S.L.1
  • 3
    • 0027401607 scopus 로고
    • The multistep nature of cancer
    • Vogelstein B, and Kinzler KW (1993). The multistep nature of cancer. Trends Genet 9, 138-141.
    • (1993) Trends Genet , vol.9 , pp. 138-141
    • Vogelstein, B.1    Kinzler, K.W.2
  • 4
    • 0028916027 scopus 로고
    • N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells
    • Ferrari G, Yan CYI, and Greene LA (1995). N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci 14, 2857-2866.
    • (1995) J Neurosci , vol.14 , pp. 2857-2866
    • Ferrari, G.1    Yan, C.Y.I.2    Greene, L.A.3
  • 6
    • 0031867657 scopus 로고    scopus 로고
    • Synchronization of cultured vascular smooth muscle cells following reversal of quiescence induced by treatment with the antioxidant N-acetylcysteine
    • Lee JS, Kypreos KE, and Sonenshein GE (1998). Synchronization of cultured vascular smooth muscle cells following reversal of quiescence induced by treatment with the antioxidant N-acetylcysteine. Exp Cell Res 239, 447-453.
    • (1998) Exp Cell Res , vol.239 , pp. 447-453
    • Lee, J.S.1    Kypreos, K.E.2    Sonenshein, G.E.3
  • 7
    • 0028905092 scopus 로고
    • Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine
    • Albini A, D'Agostini F, Giunciuglio D, Paglieri I, Balansky R, and De Flora S (1995). Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine. Int J Cancer 61, 121-129.
    • (1995) Int J Cancer , vol.61 , pp. 121-129
    • Albini, A.1    D'Agostini, F.2    Giunciuglio, D.3    Paglieri, I.4    Balansky, R.5    De Flora, S.6
  • 8
    • 0031834840 scopus 로고    scopus 로고
    • Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice
    • Balansky RM, and De Flora S (1998). Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice. Int J Cancer 77, 302-305.
    • (1998) Int J Cancer , vol.77 , pp. 302-305
    • Balansky, R.M.1    De Flora, S.2
  • 9
    • 0031849623 scopus 로고    scopus 로고
    • Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice
    • D'Agostini F, Bagnasco M, Giunciuglio D, Albini A, and De Flora S (1998). Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice. Int J Oncol 13, 217-224.
    • (1998) Int J Oncol , vol.13 , pp. 217-224
    • D'Agostini, F.1    Bagnasco, M.2    Giunciuglio, D.3    Albini, A.4    De Flora, S.5
  • 10
    • 0026043122 scopus 로고
    • Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer
    • De Flora S, Izzotti A, D'Agostini F, and Cesarone CF (1991). Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer. Am J Med 91, 122S-130S.
    • (1991) Am J Med , vol.91
    • De Flora, S.1    Izzotti, A.2    D'Agostini, F.3    Cesarone, C.F.4
  • 11
    • 0028169881 scopus 로고
    • N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro
    • Mayer M, and Noble M (1994). N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci USA 91, 7496-7500.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 7496-7500
    • Mayer, M.1    Noble, M.2
  • 12
    • 0028246870 scopus 로고
    • Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
    • Ratan RR, Murphy TH, and Baraban JM (1994). Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14, 4385-4392.
    • (1994) J Neurosci , vol.14 , pp. 4385-4392
    • Ratan, R.R.1    Murphy, T.H.2    Baraban, J.M.3
  • 14
    • 0028785523 scopus 로고
    • Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B
    • Lin K-I, Lee S-H, Narayanan R, Baraban JM, Hardwick JM, and Ratan RR (1995). Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B. J Cell Biol 131, 1149-1161.
    • (1995) J Cell Biol , vol.131 , pp. 1149-1161
    • Lin, K.-I.1    Lee, S.-H.2    Narayanan, R.3    Baraban, J.M.4    Hardwick, J.M.5    Ratan, R.R.6
  • 16
    • 0032522798 scopus 로고
    • Antioxidant action via p53-mediated apoptosis
    • Liu M, Pelling JC, Ju J, Chu E, and Brash DE (1993). Antioxidant action via p53-mediated apoptosis. Cancer Res 58, 1723-1729.
    • (1993) Cancer Res , vol.58 , pp. 1723-1729
    • Liu, M.1    Pelling, J.C.2    Ju, J.3    Chu, E.4    Brash, D.E.5
  • 19
    • 0024264526 scopus 로고
    • Glutathione metabolism and its selective modification
    • Meister A (1988). Glutathione metabolism and its selective modification. J Biol Chem 263, 17205-17208.
    • (1988) J Biol Chem , vol.263 , pp. 17205-17208
    • Meister, A.1
  • 20
    • 0024394697 scopus 로고
    • The antioxidant action of N-acetylcysteine, its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid
    • Aruoma OI, Halliwell B, Hoey BM, and Butler J (1989). The antioxidant action of N-acetylcysteine, its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid. Free Radical Biol Med 6, 593-597.
    • (1989) Free Radical Biol Med , vol.6 , pp. 593-597
    • Aruoma, O.I.1    Halliwell, B.2    Hoey, B.M.3    Butler, J.4
  • 21
    • 0025307004 scopus 로고
    • Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally?
    • Hjortso E, Fomsgaard JS, and Fogh-Andersen N (1990). Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally? Eur J Clin Pharmacol 39, 29-31.
    • (1990) Eur J Clin Pharmacol , vol.39 , pp. 29-31
    • Hjortso, E.1    Fomsgaard, J.S.2    Fogh-Andersen, N.3
  • 22
    • 0025238656 scopus 로고
    • Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress
    • Sakaida I, Kyle ME, and Farber JL (1989). Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress. Mol Pharmacol 37, 435-442.
    • (1989) Mol Pharmacol , vol.37 , pp. 435-442
    • Sakaida, I.1    Kyle, M.E.2    Farber, J.L.3
  • 23
    • 0026635457 scopus 로고
    • Iron regulation in the brain: Histochemical, biochemical, and molecular considerations
    • Connor JR, and Benkovic SA (1992). Iron regulation in the brain: histochemical, biochemical, and molecular considerations. Ann Neurol 32, S51-S61.
    • (1992) Ann Neurol , vol.32
    • Connor, J.R.1    Benkovic, S.A.2
  • 24
    • 0026568673 scopus 로고
    • Effect of iron chelators on the cytotoxic and genotoxic action of hyperoxia in Chinese hamster ovary cells
    • Gille JJP, vanBerkel CGM, and Joenje H (1992). Effect of iron chelators on the cytotoxic and genotoxic action of hyperoxia in Chinese hamster ovary cells. Mutat Res 275, 31-39.
    • (1992) Mutat Res , vol.275 , pp. 31-39
    • Gille, J.J.P.1    VanBerkel, C.G.M.2    Joenje, H.3
  • 25
    • 0027435899 scopus 로고
    • Iron induced oxidative stress and mitochondrial dysfunction relevance to Parkinson's disease
    • Hartley A, Cooper JM, and Schapira AHV (1993). Iron induced oxidative stress and mitochondrial dysfunction relevance to Parkinson's disease. Brain Res 627, 349-353.
    • (1993) Brain Res , vol.627 , pp. 349-353
    • Hartley, A.1    Cooper, J.M.2    Schapira, A.H.V.3
  • 26
    • 0025820624 scopus 로고
    • A role for oxygen radicals as second messengers
    • Schreck R, and Baeuerle PA (1991). A role for oxygen radicals as second messengers. Trends Cell Biol 1, 39-42.
    • (1991) Trends Cell Biol , vol.1 , pp. 39-42
    • Schreck, R.1    Baeuerle, P.A.2
  • 27
    • 0029005530 scopus 로고
    • Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: Role for transforming growth factor β
    • Turley JM, Funakoshi S, Ruscetti FW, Kasper J, Murphy WJ, Longo DL, and Birchenall-Roberts MC (1995). Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor β. Cell Growth Differ 6, 655-663.
    • (1995) Cell Growth Differ , vol.6 , pp. 655-663
    • Turley, J.M.1    Funakoshi, S.2    Ruscetti, F.W.3    Kasper, J.4    Murphy, W.J.5    Longo, D.L.6    Birchenall-Roberts, M.C.7
  • 28
    • 0028815621 scopus 로고
    • Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
    • Nobel CSI, Kimland M, Lind B, Orrenius S, and Slater AFG (1995). Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. J Biol Chem 270, 26202-26208.
    • (1995) J Biol Chem , vol.270 , pp. 26202-26208
    • Nobel, C.S.I.1    Kimland, M.2    Lind, B.3    Orrenius, S.4    Slater, A.F.G.5
  • 29
    • 0028470598 scopus 로고
    • Vitamin E: Molecular and biological function
    • Burton GW (1994). Vitamin E: molecular and biological function. Proc Nutr Soc 53, 251-262.
    • (1994) Proc Nutr Soc , vol.53 , pp. 251-262
    • Burton, G.W.1
  • 30
    • 0026460826 scopus 로고
    • Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant
    • Bowry VW, Ingold KU, and Stocker R (1992). Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J 288, 341-344.
    • (1992) Biochem J , vol.288 , pp. 341-344
    • Bowry, V.W.1    Ingold, K.U.2    Stocker, R.3
  • 31
    • 0029902928 scopus 로고    scopus 로고
    • Control of cell proliferation by reactive oxygen species
    • Burdon RH (1996). Control of cell proliferation by reactive oxygen species. Biochem Soc Trans 24, 1028-1032.
    • (1996) Biochem Soc Trans , vol.24 , pp. 1028-1032
    • Burdon, R.H.1
  • 32
    • 0029873387 scopus 로고    scopus 로고
    • Reactive oxygen species and programmed cell death
    • Jacobson MD (1996). Reactive oxygen species and programmed cell death. Trends Biochem Sci 21, 83-86.
    • (1996) Trends Biochem Sci , vol.21 , pp. 83-86
    • Jacobson, M.D.1
  • 33
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 34
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak K, Waldman T, He T-C, Kinzler KW, and Vogelstein B (1996). Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10, 1945-1952.
    • (1996) Genes Dev , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.-C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 36
    • 0027135637 scopus 로고
    • Cellularly generated active oxygen species and HeLa cell proliferation
    • Burdon RH, and Gill V (1993). Cellularly generated active oxygen species and HeLa cell proliferation. Free Radical Res Commun 19, 203-213.
    • (1993) Free Radical Res Commun , vol.19 , pp. 203-213
    • Burdon, R.H.1    Gill, V.2
  • 39
    • 0030670244 scopus 로고    scopus 로고
    • Characterization of interior cleavage of retinoblastoma protein in apoptosis
    • Fattman CL, An B, and Dou QP (1997). Characterization of interior cleavage of retinoblastoma protein in apoptosis. J Cell Biochem 67, 399-408.
    • (1997) J Cell Biochem , vol.67 , pp. 399-408
    • Fattman, C.L.1    An, B.2    Dou, Q.P.3
  • 40
    • 0002187866 scopus 로고    scopus 로고
    • Putative roles of retinoblastoma protein in apoptosis
    • Dou QP (1997). Putative roles of retinoblastoma protein in apoptosis. Apoptosis 2, 5-18.
    • (1997) Apoptosis , vol.2 , pp. 5-18
    • Dou, Q.P.1
  • 41
    • 0030023846 scopus 로고    scopus 로고
    • Cleavage of retinoblastoma protein during apoptosis: An interleukin 1β-converting enzyme-like protease as candidate
    • An B, and Dou QP (1996). Cleavage of retinoblastoma protein during apoptosis: an interleukin 1β-converting enzyme-like protease as candidate. Cancer Res 56, 438-442.
    • (1996) Cancer Res , vol.56 , pp. 438-442
    • An, B.1    Dou, Q.P.2
  • 42
    • 0032031417 scopus 로고    scopus 로고
    • The caspase-RB connection in cell death
    • Tan X, and Wang JY (1998). The caspase-RB connection in cell death. Trends Cell Biol 8, 116-120.
    • (1998) Trends Cell Biol , vol.8 , pp. 116-120
    • Tan, X.1    Wang, J.Y.2
  • 43
    • 0030462563 scopus 로고    scopus 로고
    • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
    • Janicke RU, Walker PA, Lin XY, and Porter AG (1996). Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J 15, 6969-6978.
    • (1996) EMBO J , vol.15 , pp. 6969-6978
    • Janicke, R.U.1    Walker, P.A.2    Lin, X.Y.3    Porter, A.G.4
  • 48
    • 0030011128 scopus 로고    scopus 로고
    • Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
    • Waldman T, Lengauer C, Kinzler KW, and Vogelstein B (1996). Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716.
    • (1996) Nature , vol.381 , pp. 713-716
    • Waldman, T.1    Lengauer, C.2    Kinzler, K.W.3    Vogelstein, B.4
  • 53
    • 0028110809 scopus 로고
    • Hypoxia induced accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
    • Graeber TG, Peterson JF, Tsai M, Monica K, Fomace AJ, and Giaccia AJ (1994). Hypoxia induced accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol 14, 6264-6277.
    • (1994) Mol Cell Biol , vol.14 , pp. 6264-6277
    • Graeber, T.G.1    Peterson, J.F.2    Tsai, M.3    Monica, K.4    Fomace, A.J.5    Giaccia, A.J.6
  • 54
    • 0028864695 scopus 로고
    • N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent
    • Yan CYI, Ferrari G, and Greene LA (1995). N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent. J Biol Chem 270, 26827-26832.
    • (1995) J Biol Chem , vol.270 , pp. 26827-26832
    • Yan, C.Y.I.1    Ferrari, G.2    Greene, L.A.3
  • 55
    • 0027496935 scopus 로고
    • The 21 Kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami G, Wei N, Keyomarsi K, and Elledge SJ (1993). The 21 Kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 57
    • 0028342664 scopus 로고
    • Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
    • Noda A, Ning Y, Venable SF, Pereira-Smith OM, and Smith JR (1994). Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211, 90-98.
    • (1994) Exp Cell Res , vol.211 , pp. 90-98
    • Noda, A.1    Ning, Y.2    Venable, S.F.3    Pereira-Smith, O.M.4    Smith, J.R.5
  • 58
    • 0028363519 scopus 로고
    • p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
    • Totoshima H, and Hunter T (1994). p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78, 67-74.
    • (1994) Cell , vol.78 , pp. 67-74
    • Totoshima, H.1    Hunter, T.2
  • 59
    • 0028176483 scopus 로고
    • Cloning of p27 KlP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals
    • Polyak K, Lee M-H, Erdjument-Bromage H, Tempst P, and Massague J (1994). Cloning of p27 KlP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals. Cell 78, 59-66.
    • (1994) Cell , vol.78 , pp. 59-66
    • Polyak, K.1    Lee, M.-H.2    Erdjument-Bromage, H.3    Tempst, P.4    Massague, J.5
  • 61
    • 0028988158 scopus 로고
    • Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
    • Lee M-H, Reynisdottir I, and Massague J (1995). Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9, 639-649.
    • (1995) Genes Dev , vol.9 , pp. 639-649
    • Lee, M.-H.1    Reynisdottir, I.2    Massague, J.3
  • 63
    • 0027769876 scopus 로고
    • A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
    • Serrano M, Hannon GJ, and Beach D (1993). A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366, 704-707.
    • (1993) Nature , vol.366 , pp. 704-707
    • Serrano, M.1    Hannon, G.J.2    Beach, D.3
  • 64
    • 0028168242 scopus 로고
    • INK4B is a potential effector of TGF-β induced cell cycle arrest
    • INK4B is a potential effector of TGF-β induced cell cycle arrest. Nature 371, 257-261.
    • (1994) Nature , vol.371 , pp. 257-261
    • Hannon, G.J.1    Beach, D.2
  • 67
    • 0028918388 scopus 로고
    • Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin dependent kinases Cdk4 and Cdk6
    • Hirai H, Roussel MF, Kato JY, Ashmun RA, and Sherr C (1995). Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin dependent kinases Cdk4 and Cdk6. Mol Cell Biol 15, 2672-2681.
    • (1995) Mol Cell Biol , vol.15 , pp. 2672-2681
    • Hirai, H.1    Roussel, M.F.2    Kato, J.Y.3    Ashmun, R.A.4    Sherr, C.5
  • 69
    • 0031016121 scopus 로고    scopus 로고
    • RB kinases and RB-binding proteins: New points of view
    • Taya Y (1997). RB kinases and RB-binding proteins: new points of view. Trends Biochem Sci 22, 14-17.
    • (1997) Trends Biochem Sci , vol.22 , pp. 14-17
    • Taya, Y.1
  • 70
    • 0031915575 scopus 로고    scopus 로고
    • Proteolytic cleavage of retinoblastoma protein upon DNA damage and Fas-mediated apoptosis
    • Diederich L, Fotedar A, and Fotedar R (1998). Proteolytic cleavage of retinoblastoma protein upon DNA damage and Fas-mediated apoptosis. Cell Biol Toxicol 14, 133-140.
    • (1998) Cell Biol Toxicol , vol.14 , pp. 133-140
    • Diederich, L.1    Fotedar, A.2    Fotedar, R.3
  • 71
    • 0032516708 scopus 로고    scopus 로고
    • p53-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells
    • Fattman CL, An B, Sussman L, and Dou QP (1998). p53-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells. Cancer Lett 130, 103-113.
    • (1998) Cancer Lett , vol.130 , pp. 103-113
    • Fattman, C.L.1    An, B.2    Sussman, L.3    Dou, Q.P.4
  • 74
    • 0021964203 scopus 로고
    • Prooxidant states and tumor promotion
    • Cerutti PA (1985). Prooxidant states and tumor promotion. Science 227, 375-381.
    • (1985) Science , vol.227 , pp. 375-381
    • Cerutti, P.A.1
  • 75
    • 0004707849 scopus 로고
    • Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate
    • Borek C, and Troll W (1983). Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. Proc Natl Acad Sci U S A 80, 1304-1307.
    • (1983) Proc Natl Acad Sci U S A , vol.80 , pp. 1304-1307
    • Borek, C.1    Troll, W.2
  • 76
    • 0020530692 scopus 로고
    • Inhibition of tumor promotion by a biomimetic superoxide dismutase
    • Kensler TW, Bush DM, and Kozumbo WJ (1983). Inhibition of tumor promotion by a biomimetic superoxide dismutase. Science 221, 75-77.
    • (1983) Science , vol.221 , pp. 75-77
    • Kensler, T.W.1    Bush, D.M.2    Kozumbo, W.J.3
  • 77
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid β protein toxicity
    • Behl C, Davis JB, Lesley R, and Schubert D (1994). Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77, 817-827.
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 78
    • 0030024241 scopus 로고    scopus 로고
    • Role of p21 in prostaglandin A2-mediated cellular arrest and death
    • Gorospe M, and Holbrook NJ (1996). Role of p21 in prostaglandin A2-mediated cellular arrest and death. Cancer Res 56, 475-479.
    • (1996) Cancer Res , vol.56 , pp. 475-479
    • Gorospe, M.1    Holbrook, N.J.2
  • 79
    • 0029956387 scopus 로고    scopus 로고
    • Wat1/Cip1 against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells
    • Wat1/Cip1 against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells. Mol Cell Biol 16, 6654-6660.
    • (1996) Mol Cell Biol , vol.16 , pp. 6654-6660
    • Gorospe, M.1    Wang, X.2    Guyton, K.Z.3    Holbrook, N.J.4
  • 81
    • 0032510026 scopus 로고    scopus 로고
    • Waf1/Cip1/Sdi1 lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells
    • Waf1/Cip1/Sdi1 lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells. Oncogene 16, 705-712.
    • (1998) Oncogene , vol.16 , pp. 705-712
    • Lu, Y.1    Yamagishi, N.2    Yagi, T.3    Takebe, H.4
  • 82
    • 0024312892 scopus 로고
    • Rapid detection of ras oncogenes in human tumors: Applications to colon, esophageal, and gastric cancer
    • Jiang W, Kahn SM, Guillem JG, Lu S-H, and Weinstein IB (1989). Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. Oncogene 4, 923-928.
    • (1989) Oncogene , vol.4 , pp. 923-928
    • Jiang, W.1    Kahn, S.M.2    Guillem, J.G.3    Lu, S.-H.4    Weinstein, I.B.5
  • 86
    • 0020561660 scopus 로고
    • Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye
    • Bernai SD, Lampidis TJ, McIsaac RM, and Chen LB (1983). Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye. Science 222, 169-172.
    • (1983) Science , vol.222 , pp. 169-172
    • Bernai, S.D.1    Lampidis, T.J.2    McIsaac, R.M.3    Chen, L.B.4
  • 88
    • 0020060701 scopus 로고
    • Decreased uptake and retention of rhodamine 123 by mitochondria in feline sarcoma virus-transformed mink cells
    • Johnson LV, Summerhayes IC, and Chen LB (1982). Decreased uptake and retention of rhodamine 123 by mitochondria in feline sarcoma virus-transformed mink cells. Cell 28, 7-14.
    • (1982) Cell , vol.28 , pp. 7-14
    • Johnson, L.V.1    Summerhayes, I.C.2    Chen, L.B.3
  • 89
    • 0020695797 scopus 로고
    • Selective toxicity of rhodamine 123 in carcinoma cells in vitro
    • Lampidis TJ, Bernal SD, Summerhayes IC, and Chen LB (1983). Selective toxicity of rhodamine 123 in carcinoma cells in vitro. Cancer Res 43, 716-720.
    • (1983) Cancer Res , vol.43 , pp. 716-720
    • Lampidis, T.J.1    Bernal, S.D.2    Summerhayes, I.C.3    Chen, L.B.4
  • 91
    • 0020428221 scopus 로고
    • Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro
    • Bernal SD, Lampidis TJ, Summerhayes IC, and Chen LB (1982). Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro. Science 218, 1117-1119.
    • (1982) Science , vol.218 , pp. 1117-1119
    • Bernal, S.D.1    Lampidis, T.J.2    Summerhayes, I.C.3    Chen, L.B.4
  • 92
    • 0028605882 scopus 로고
    • Antioxidants and carcinogenesis
    • Rautalahti M, and Huttunen J (1993). Antioxidants and carcinogenesis. Ann Med 25, 435-441.
    • (1993) Ann Med , vol.25 , pp. 435-441
    • Rautalahti, M.1    Huttunen, J.2


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