-
1
-
-
0031990918
-
Antioxidant supplements and colorectal cancer
-
Konings E, and Greenberg ER (1998). Antioxidant supplements and colorectal cancer. Nutrition 14, 245-247.
-
(1998)
Nutrition
, vol.14
, pp. 245-247
-
-
Konings, E.1
Greenberg, E.R.2
-
2
-
-
0030043446
-
Cancer statistics
-
Parker SL (1996). Cancer statistics. Ca-Cancer J Clin 46, 5-27.
-
(1996)
Ca-Cancer J Clin
, vol.46
, pp. 5-27
-
-
Parker, S.L.1
-
3
-
-
0027401607
-
The multistep nature of cancer
-
Vogelstein B, and Kinzler KW (1993). The multistep nature of cancer. Trends Genet 9, 138-141.
-
(1993)
Trends Genet
, vol.9
, pp. 138-141
-
-
Vogelstein, B.1
Kinzler, K.W.2
-
4
-
-
0028916027
-
N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells
-
Ferrari G, Yan CYI, and Greene LA (1995). N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic death of neuronal cells. J Neurosci 14, 2857-2866.
-
(1995)
J Neurosci
, vol.14
, pp. 2857-2866
-
-
Ferrari, G.1
Yan, C.Y.I.2
Greene, L.A.3
-
5
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, and Goldschmidt-Clermont PJ (1997). Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275, 1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
6
-
-
0031867657
-
Synchronization of cultured vascular smooth muscle cells following reversal of quiescence induced by treatment with the antioxidant N-acetylcysteine
-
Lee JS, Kypreos KE, and Sonenshein GE (1998). Synchronization of cultured vascular smooth muscle cells following reversal of quiescence induced by treatment with the antioxidant N-acetylcysteine. Exp Cell Res 239, 447-453.
-
(1998)
Exp Cell Res
, vol.239
, pp. 447-453
-
-
Lee, J.S.1
Kypreos, K.E.2
Sonenshein, G.E.3
-
7
-
-
0028905092
-
Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine
-
Albini A, D'Agostini F, Giunciuglio D, Paglieri I, Balansky R, and De Flora S (1995). Inhibition of invasion, gelatinase activity, tumor take and metastasis of malignant cells by N-acetylcysteine. Int J Cancer 61, 121-129.
-
(1995)
Int J Cancer
, vol.61
, pp. 121-129
-
-
Albini, A.1
D'Agostini, F.2
Giunciuglio, D.3
Paglieri, I.4
Balansky, R.5
De Flora, S.6
-
8
-
-
0031834840
-
Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice
-
Balansky RM, and De Flora S (1998). Chemoprevention by N-acetylcysteine of urethane-induced clastogenicity and lung tumors in mice. Int J Cancer 77, 302-305.
-
(1998)
Int J Cancer
, vol.77
, pp. 302-305
-
-
Balansky, R.M.1
De Flora, S.2
-
9
-
-
0031849623
-
Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice
-
D'Agostini F, Bagnasco M, Giunciuglio D, Albini A, and De Flora S (1998). Inhibition by oral N-acetylcysteine of doxorubicin-induced clastogenicity and alopecia, and prevention of primary tumors and lung micrometastases in mice. Int J Oncol 13, 217-224.
-
(1998)
Int J Oncol
, vol.13
, pp. 217-224
-
-
D'Agostini, F.1
Bagnasco, M.2
Giunciuglio, D.3
Albini, A.4
De Flora, S.5
-
10
-
-
0026043122
-
Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer
-
De Flora S, Izzotti A, D'Agostini F, and Cesarone CF (1991). Antioxidant activity and other mechanisms of thiols involved in chemoprevention of mutation and cancer. Am J Med 91, 122S-130S.
-
(1991)
Am J Med
, vol.91
-
-
De Flora, S.1
Izzotti, A.2
D'Agostini, F.3
Cesarone, C.F.4
-
11
-
-
0028169881
-
N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro
-
Mayer M, and Noble M (1994). N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci USA 91, 7496-7500.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 7496-7500
-
-
Mayer, M.1
Noble, M.2
-
12
-
-
0028246870
-
Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione
-
Ratan RR, Murphy TH, and Baraban JM (1994). Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione. J Neurosci 14, 4385-4392.
-
(1994)
J Neurosci
, vol.14
, pp. 4385-4392
-
-
Ratan, R.R.1
Murphy, T.H.2
Baraban, J.M.3
-
13
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
Hockenbery DM, Oltvai ZN, Yin X-M, Milliman CL, and Korsmeyer SJ (1993). Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251.
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.-M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
14
-
-
0028785523
-
Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B
-
Lin K-I, Lee S-H, Narayanan R, Baraban JM, Hardwick JM, and Ratan RR (1995). Thiol agents and Bcl-2 identify an alphavirus-induced apoptotic pathway that requires activation of the transcription factor NF-kappa B. J Cell Biol 131, 1149-1161.
-
(1995)
J Cell Biol
, vol.131
, pp. 1149-1161
-
-
Lin, K.-I.1
Lee, S.-H.2
Narayanan, R.3
Baraban, J.M.4
Hardwick, J.M.5
Ratan, R.R.6
-
15
-
-
0029958381
-
Reactive oxygen species are downstream mediators of p53-dependent apoptosis
-
Johnson TM, Yu Z-X, Ferrans VJ, Lowenstein RA, and Finkel T (1996). Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Proc Natl Acad Sci USA 93, 11848-11852.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 11848-11852
-
-
Johnson, T.M.1
Yu, Z.-X.2
Ferrans, V.J.3
Lowenstein, R.A.4
Finkel, T.5
-
16
-
-
0032522798
-
Antioxidant action via p53-mediated apoptosis
-
Liu M, Pelling JC, Ju J, Chu E, and Brash DE (1993). Antioxidant action via p53-mediated apoptosis. Cancer Res 58, 1723-1729.
-
(1993)
Cancer Res
, vol.58
, pp. 1723-1729
-
-
Liu, M.1
Pelling, J.C.2
Ju, J.3
Chu, E.4
Brash, D.E.5
-
18
-
-
13344279414
-
Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells
-
Tsai J-C, Jain M, Hsieh C-M, Lee W-S, Yoshizumi M, Patterson C, Perrella MA, Cooke C, Wang H, Haber E, Schlegel R, and Lee M-E (1996). Induction of apoptosis by pyrrolidinedithiocarbamate and N-acetylcysteine in vascular smooth muscle cells. J Biol Chem 271, 3667-3670.
-
(1996)
J Biol Chem
, vol.271
, pp. 3667-3670
-
-
Tsai, J.-C.1
Jain, M.2
Hsieh, C.-M.3
Lee, W.-S.4
Yoshizumi, M.5
Patterson, C.6
Perrella, M.A.7
Cooke, C.8
Wang, H.9
Haber, E.10
Schlegel, R.11
Lee, M.-E.12
-
19
-
-
0024264526
-
Glutathione metabolism and its selective modification
-
Meister A (1988). Glutathione metabolism and its selective modification. J Biol Chem 263, 17205-17208.
-
(1988)
J Biol Chem
, vol.263
, pp. 17205-17208
-
-
Meister, A.1
-
20
-
-
0024394697
-
The antioxidant action of N-acetylcysteine, its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid
-
Aruoma OI, Halliwell B, Hoey BM, and Butler J (1989). The antioxidant action of N-acetylcysteine, its reaction with hydrogen peroxide, hydroxyl radical, superoxide and hypochlorous acid. Free Radical Biol Med 6, 593-597.
-
(1989)
Free Radical Biol Med
, vol.6
, pp. 593-597
-
-
Aruoma, O.I.1
Halliwell, B.2
Hoey, B.M.3
Butler, J.4
-
21
-
-
0025307004
-
Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally?
-
Hjortso E, Fomsgaard JS, and Fogh-Andersen N (1990). Does N-acetylcysteine increase the excretion of trace metals (calcium, magnesium, iron, zinc and copper) when given orally? Eur J Clin Pharmacol 39, 29-31.
-
(1990)
Eur J Clin Pharmacol
, vol.39
, pp. 29-31
-
-
Hjortso, E.1
Fomsgaard, J.S.2
Fogh-Andersen, N.3
-
22
-
-
0025238656
-
Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress
-
Sakaida I, Kyle ME, and Farber JL (1989). Autophagic degradation of protein generates a pool of ferric iron required for the killing of cultured hepatocytes by an oxidative stress. Mol Pharmacol 37, 435-442.
-
(1989)
Mol Pharmacol
, vol.37
, pp. 435-442
-
-
Sakaida, I.1
Kyle, M.E.2
Farber, J.L.3
-
23
-
-
0026635457
-
Iron regulation in the brain: Histochemical, biochemical, and molecular considerations
-
Connor JR, and Benkovic SA (1992). Iron regulation in the brain: histochemical, biochemical, and molecular considerations. Ann Neurol 32, S51-S61.
-
(1992)
Ann Neurol
, vol.32
-
-
Connor, J.R.1
Benkovic, S.A.2
-
24
-
-
0026568673
-
Effect of iron chelators on the cytotoxic and genotoxic action of hyperoxia in Chinese hamster ovary cells
-
Gille JJP, vanBerkel CGM, and Joenje H (1992). Effect of iron chelators on the cytotoxic and genotoxic action of hyperoxia in Chinese hamster ovary cells. Mutat Res 275, 31-39.
-
(1992)
Mutat Res
, vol.275
, pp. 31-39
-
-
Gille, J.J.P.1
VanBerkel, C.G.M.2
Joenje, H.3
-
25
-
-
0027435899
-
Iron induced oxidative stress and mitochondrial dysfunction relevance to Parkinson's disease
-
Hartley A, Cooper JM, and Schapira AHV (1993). Iron induced oxidative stress and mitochondrial dysfunction relevance to Parkinson's disease. Brain Res 627, 349-353.
-
(1993)
Brain Res
, vol.627
, pp. 349-353
-
-
Hartley, A.1
Cooper, J.M.2
Schapira, A.H.V.3
-
26
-
-
0025820624
-
A role for oxygen radicals as second messengers
-
Schreck R, and Baeuerle PA (1991). A role for oxygen radicals as second messengers. Trends Cell Biol 1, 39-42.
-
(1991)
Trends Cell Biol
, vol.1
, pp. 39-42
-
-
Schreck, R.1
Baeuerle, P.A.2
-
27
-
-
0029005530
-
Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: Role for transforming growth factor β
-
Turley JM, Funakoshi S, Ruscetti FW, Kasper J, Murphy WJ, Longo DL, and Birchenall-Roberts MC (1995). Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor β. Cell Growth Differ 6, 655-663.
-
(1995)
Cell Growth Differ
, vol.6
, pp. 655-663
-
-
Turley, J.M.1
Funakoshi, S.2
Ruscetti, F.W.3
Kasper, J.4
Murphy, W.J.5
Longo, D.L.6
Birchenall-Roberts, M.C.7
-
28
-
-
0028815621
-
Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper
-
Nobel CSI, Kimland M, Lind B, Orrenius S, and Slater AFG (1995). Dithiocarbamates induce apoptosis in thymocytes by raising the intracellular level of redox-active copper. J Biol Chem 270, 26202-26208.
-
(1995)
J Biol Chem
, vol.270
, pp. 26202-26208
-
-
Nobel, C.S.I.1
Kimland, M.2
Lind, B.3
Orrenius, S.4
Slater, A.F.G.5
-
29
-
-
0028470598
-
Vitamin E: Molecular and biological function
-
Burton GW (1994). Vitamin E: molecular and biological function. Proc Nutr Soc 53, 251-262.
-
(1994)
Proc Nutr Soc
, vol.53
, pp. 251-262
-
-
Burton, G.W.1
-
30
-
-
0026460826
-
Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant
-
Bowry VW, Ingold KU, and Stocker R (1992). Vitamin E in human low-density lipoprotein. When and how this antioxidant becomes a pro-oxidant. Biochem J 288, 341-344.
-
(1992)
Biochem J
, vol.288
, pp. 341-344
-
-
Bowry, V.W.1
Ingold, K.U.2
Stocker, R.3
-
31
-
-
0029902928
-
Control of cell proliferation by reactive oxygen species
-
Burdon RH (1996). Control of cell proliferation by reactive oxygen species. Biochem Soc Trans 24, 1028-1032.
-
(1996)
Biochem Soc Trans
, vol.24
, pp. 1028-1032
-
-
Burdon, R.H.1
-
32
-
-
0029873387
-
Reactive oxygen species and programmed cell death
-
Jacobson MD (1996). Reactive oxygen species and programmed cell death. Trends Biochem Sci 21, 83-86.
-
(1996)
Trends Biochem Sci
, vol.21
, pp. 83-86
-
-
Jacobson, M.D.1
-
33
-
-
0030941458
-
p53, the cellular gatekeeper for growth and division
-
Levine AJ (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
-
(1997)
Cell
, vol.88
, pp. 323-331
-
-
Levine, A.J.1
-
34
-
-
0029811984
-
Genetic determinants of p53-induced apoptosis and growth arrest
-
Polyak K, Waldman T, He T-C, Kinzler KW, and Vogelstein B (1996). Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10, 1945-1952.
-
(1996)
Genes Dev
, vol.10
, pp. 1945-1952
-
-
Polyak, K.1
Waldman, T.2
He, T.-C.3
Kinzler, K.W.4
Vogelstein, B.5
-
35
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, and Vogelstein B (1997). A model for p53-induced apoptosis. Nature 389, 300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
36
-
-
0027135637
-
Cellularly generated active oxygen species and HeLa cell proliferation
-
Burdon RH, and Gill V (1993). Cellularly generated active oxygen species and HeLa cell proliferation. Free Radical Res Commun 19, 203-213.
-
(1993)
Free Radical Res Commun
, vol.19
, pp. 203-213
-
-
Burdon, R.H.1
Gill, V.2
-
38
-
-
0026744563
-
Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
-
Lee EY-HP, Chang C-Y, Hu N, Wang Y-CJ, Lai C-C, Herrup K, Lee W-H, and Bradley A (1992). Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis. Nature 359, 288-294.
-
(1992)
Nature
, vol.359
, pp. 288-294
-
-
Lee, E.Y.-H.P.1
Chang, C.-Y.2
Hu, N.3
Wang, Y.-C.J.4
Lai, C.-C.5
Herrup, K.6
Lee, W.-H.7
Bradley, A.8
-
39
-
-
0030670244
-
Characterization of interior cleavage of retinoblastoma protein in apoptosis
-
Fattman CL, An B, and Dou QP (1997). Characterization of interior cleavage of retinoblastoma protein in apoptosis. J Cell Biochem 67, 399-408.
-
(1997)
J Cell Biochem
, vol.67
, pp. 399-408
-
-
Fattman, C.L.1
An, B.2
Dou, Q.P.3
-
40
-
-
0002187866
-
Putative roles of retinoblastoma protein in apoptosis
-
Dou QP (1997). Putative roles of retinoblastoma protein in apoptosis. Apoptosis 2, 5-18.
-
(1997)
Apoptosis
, vol.2
, pp. 5-18
-
-
Dou, Q.P.1
-
41
-
-
0030023846
-
Cleavage of retinoblastoma protein during apoptosis: An interleukin 1β-converting enzyme-like protease as candidate
-
An B, and Dou QP (1996). Cleavage of retinoblastoma protein during apoptosis: an interleukin 1β-converting enzyme-like protease as candidate. Cancer Res 56, 438-442.
-
(1996)
Cancer Res
, vol.56
, pp. 438-442
-
-
An, B.1
Dou, Q.P.2
-
42
-
-
0032031417
-
The caspase-RB connection in cell death
-
Tan X, and Wang JY (1998). The caspase-RB connection in cell death. Trends Cell Biol 8, 116-120.
-
(1998)
Trends Cell Biol
, vol.8
, pp. 116-120
-
-
Tan, X.1
Wang, J.Y.2
-
43
-
-
0030462563
-
Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis
-
Janicke RU, Walker PA, Lin XY, and Porter AG (1996). Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis. EMBO J 15, 6969-6978.
-
(1996)
EMBO J
, vol.15
, pp. 6969-6978
-
-
Janicke, R.U.1
Walker, P.A.2
Lin, X.Y.3
Porter, A.G.4
-
44
-
-
0026656853
-
Wildtype p53 is a cell cycle checkpoint determinant following irradiation
-
Kuerbitz SJ, Plunkett BS, Walsh WV, and Kastan MB (1992). Wildtype p53 is a cell cycle checkpoint determinant following irradiation. Proc Natl Acad Sci USA 89, 7491-7495.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7491-7495
-
-
Kuerbitz, S.J.1
Plunkett, B.S.2
Walsh, W.V.3
Kastan, M.B.4
-
45
-
-
0025040233
-
Suppression of human colorectal carcinoma cell growth by wild-type p53
-
Baker SJ, Markowitz S, Fearon ER, Willson JKV, and Vogelstein B (1990). Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249, 912-915.
-
(1990)
Science
, vol.249
, pp. 912-915
-
-
Baker, S.J.1
Markowitz, S.2
Fearon, E.R.3
Willson, J.K.V.4
Vogelstein, B.5
-
46
-
-
0027266971
-
Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage
-
Kessis TD, Slebos RJ, Nelson WG, Kastan MB, Plunkett BS, Han SM, Lorincz AT, Hedrick L, and Cho KR (1993). Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc Natl Acad Sci USA 90, 3988-3992.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3988-3992
-
-
Kessis, T.D.1
Slebos, R.J.2
Nelson, W.G.3
Kastan, M.B.4
Plunkett, B.S.5
Han, S.M.6
Lorincz, A.T.7
Hedrick, L.8
Cho, K.R.9
-
48
-
-
0030011128
-
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21
-
Waldman T, Lengauer C, Kinzler KW, and Vogelstein B (1996). Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21. Nature 381, 713-716.
-
(1996)
Nature
, vol.381
, pp. 713-716
-
-
Waldman, T.1
Lengauer, C.2
Kinzler, K.W.3
Vogelstein, B.4
-
50
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, and Vogelstein B (1993). WAF1, a potential mediator of p53 tumor suppression. Cell 75, 817-825.
-
(1993)
Cell
, vol.75
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
51
-
-
0024536654
-
Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas
-
Baker SJ, Fearon ER, Nigro JM, Hamilton SR, Preisinger AC, Jessup JM, vanTuinen P, Ledbetter DH, Barker DF, Nakamura Y, White R, and Vogelstein B (1989). Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas. Science 244, 217-221.
-
(1989)
Science
, vol.244
, pp. 217-221
-
-
Baker, S.J.1
Fearon, E.R.2
Nigro, J.M.3
Hamilton, S.R.4
Preisinger, A.C.5
Jessup, J.M.6
VanTuinen, P.7
Ledbetter, D.H.8
Barker, D.F.9
Nakamura, Y.10
White, R.11
Vogelstein, B.12
-
52
-
-
0024387728
-
Mutations in the p53 gene occur in diverse human tumour types
-
Nigro JM, Baker SJ, Preisinger AC, Jessup JM, Hostetter R, Cleary K, Bigner SH, Davidson N, Baylin S, Devilee P, Glover T, Collins FS, Weston A, Modali R, Harris CC, and Vogelstein B (1989). Mutations in the p53 gene occur in diverse human tumour types. Nature 342, 705-708.
-
(1989)
Nature
, vol.342
, pp. 705-708
-
-
Nigro, J.M.1
Baker, S.J.2
Preisinger, A.C.3
Jessup, J.M.4
Hostetter, R.5
Cleary, K.6
Bigner, S.H.7
Davidson, N.8
Baylin, S.9
Devilee, P.10
Glover, T.11
Collins, F.S.12
Weston, A.13
Modali, R.14
Harris, C.C.15
Vogelstein, B.16
-
53
-
-
0028110809
-
Hypoxia induced accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status
-
Graeber TG, Peterson JF, Tsai M, Monica K, Fomace AJ, and Giaccia AJ (1994). Hypoxia induced accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status. Mol Cell Biol 14, 6264-6277.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 6264-6277
-
-
Graeber, T.G.1
Peterson, J.F.2
Tsai, M.3
Monica, K.4
Fomace, A.J.5
Giaccia, A.J.6
-
54
-
-
0028864695
-
N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent
-
Yan CYI, Ferrari G, and Greene LA (1995). N-acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent. J Biol Chem 270, 26827-26832.
-
(1995)
J Biol Chem
, vol.270
, pp. 26827-26832
-
-
Yan, C.Y.I.1
Ferrari, G.2
Greene, L.A.3
-
55
-
-
0027496935
-
The 21 Kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
-
Harper JW, Adami G, Wei N, Keyomarsi K, and Elledge SJ (1993). The 21 Kd Cdk interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75, 805-816.
-
(1993)
Cell
, vol.75
, pp. 805-816
-
-
Harper, J.W.1
Adami, G.2
Wei, N.3
Keyomarsi, K.4
Elledge, S.J.5
-
56
-
-
0027717617
-
p21 is a universal inhibitor of cyclin kinases
-
Xiong Y, Hannon GJ, Zhang GJ, Casso D, Kobayashi R, and Beach D (1993). p21 is a universal inhibitor of cyclin kinases. Nature 366, 701-704.
-
(1993)
Nature
, vol.366
, pp. 701-704
-
-
Xiong, Y.1
Hannon, G.J.2
Zhang, G.J.3
Casso, D.4
Kobayashi, R.5
Beach, D.6
-
57
-
-
0028342664
-
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen
-
Noda A, Ning Y, Venable SF, Pereira-Smith OM, and Smith JR (1994). Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen. Exp Cell Res 211, 90-98.
-
(1994)
Exp Cell Res
, vol.211
, pp. 90-98
-
-
Noda, A.1
Ning, Y.2
Venable, S.F.3
Pereira-Smith, O.M.4
Smith, J.R.5
-
58
-
-
0028363519
-
p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21
-
Totoshima H, and Hunter T (1994). p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21. Cell 78, 67-74.
-
(1994)
Cell
, vol.78
, pp. 67-74
-
-
Totoshima, H.1
Hunter, T.2
-
59
-
-
0028176483
-
Cloning of p27 KlP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals
-
Polyak K, Lee M-H, Erdjument-Bromage H, Tempst P, and Massague J (1994). Cloning of p27 KlP1, a cyclin-dependent kinase inhibitor and potential mediator of extracellular antimitogenic signals. Cell 78, 59-66.
-
(1994)
Cell
, vol.78
, pp. 59-66
-
-
Polyak, K.1
Lee, M.-H.2
Erdjument-Bromage, H.3
Tempst, P.4
Massague, J.5
-
60
-
-
0028988159
-
CIP1 Cdk-inhibitor family, is a candidate tumor suppressor gene
-
CIP1 Cdk-inhibitor family, is a candidate tumor suppressor gene. Genes Dev 9, 650-662.
-
(1995)
Genes Dev
, vol.9
, pp. 650-662
-
-
Matsuoka, S.1
Edwards, M.2
Bai, C.3
Parker, S.4
Zhang, P.5
Baldini, A.6
Harper, J.W.7
Elledge, S.J.8
-
61
-
-
0028988158
-
Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution
-
Lee M-H, Reynisdottir I, and Massague J (1995). Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9, 639-649.
-
(1995)
Genes Dev
, vol.9
, pp. 639-649
-
-
Lee, M.-H.1
Reynisdottir, I.2
Massague, J.3
-
62
-
-
0029058587
-
Inhibition of cyclin-dependent kinases by p21
-
Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, Zhang P, Dobrowolski S, Bai C, Connell-Crowley L, and Swindell E (1995). Inhibition of cyclin-dependent kinases by p21. Mol Biol Cell 6, 387-400.
-
(1995)
Mol Biol Cell
, vol.6
, pp. 387-400
-
-
Harper, J.W.1
Elledge, S.J.2
Keyomarsi, K.3
Dynlacht, B.4
Tsai, L.H.5
Zhang, P.6
Dobrowolski, S.7
Bai, C.8
Connell-Crowley, L.9
Swindell, E.10
-
63
-
-
0027769876
-
A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4
-
Serrano M, Hannon GJ, and Beach D (1993). A new regulatory motif in cell cycle control causing specific inhibition of cyclin D/CDK4. Nature 366, 704-707.
-
(1993)
Nature
, vol.366
, pp. 704-707
-
-
Serrano, M.1
Hannon, G.J.2
Beach, D.3
-
64
-
-
0028168242
-
INK4B is a potential effector of TGF-β induced cell cycle arrest
-
INK4B is a potential effector of TGF-β induced cell cycle arrest. Nature 371, 257-261.
-
(1994)
Nature
, vol.371
, pp. 257-261
-
-
Hannon, G.J.1
Beach, D.2
-
65
-
-
0028618304
-
Deletion of p16 and p15 genes in brain tumors
-
Jen J, Harper JW, Bigner SH, Bigner DD, Papadopoulos N, Markowitz S, Willson JKV, Kinzler KW, and Vogelstein B (1994). Deletion of p16 and p15 genes in brain tumors. Cancer Res 54, 6353-6358.
-
(1994)
Cancer Res
, vol.54
, pp. 6353-6358
-
-
Jen, J.1
Harper, J.W.2
Bigner, S.H.3
Bigner, D.D.4
Papadopoulos, N.5
Markowitz, S.6
Willson, J.K.V.7
Kinzler, K.W.8
Vogelstein, B.9
-
66
-
-
0028582034
-
INK4b/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function
-
INK4b/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function. Genes Dev 8, 2939-2952.
-
(1994)
Genes Dev
, vol.8
, pp. 2939-2952
-
-
Guan, K.1
Jenkins, C.W.2
Li, Y.3
Nichols, M.A.4
Wu, X.5
O'Keefe, C.L.6
Matera, A.G.7
Xiong, Y.8
-
67
-
-
0028918388
-
Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin dependent kinases Cdk4 and Cdk6
-
Hirai H, Roussel MF, Kato JY, Ashmun RA, and Sherr C (1995). Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin dependent kinases Cdk4 and Cdk6. Mol Cell Biol 15, 2672-2681.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 2672-2681
-
-
Hirai, H.1
Roussel, M.F.2
Kato, J.Y.3
Ashmun, R.A.4
Sherr, C.5
-
69
-
-
0031016121
-
RB kinases and RB-binding proteins: New points of view
-
Taya Y (1997). RB kinases and RB-binding proteins: new points of view. Trends Biochem Sci 22, 14-17.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 14-17
-
-
Taya, Y.1
-
70
-
-
0031915575
-
Proteolytic cleavage of retinoblastoma protein upon DNA damage and Fas-mediated apoptosis
-
Diederich L, Fotedar A, and Fotedar R (1998). Proteolytic cleavage of retinoblastoma protein upon DNA damage and Fas-mediated apoptosis. Cell Biol Toxicol 14, 133-140.
-
(1998)
Cell Biol Toxicol
, vol.14
, pp. 133-140
-
-
Diederich, L.1
Fotedar, A.2
Fotedar, R.3
-
71
-
-
0032516708
-
p53-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells
-
Fattman CL, An B, Sussman L, and Dou QP (1998). p53-independent dephosphorylation and cleavage of retinoblastoma protein during tamoxifen-induced apoptosis in human breast carcinoma cells. Cancer Lett 130, 103-113.
-
(1998)
Cancer Lett
, vol.130
, pp. 103-113
-
-
Fattman, C.L.1
An, B.2
Sussman, L.3
Dou, Q.P.4
-
72
-
-
0028177401
-
p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein
-
Slebos RJC, Lee MH, Plunkett BS, Kessis TD, Williams BO, Jacks T, Hedrick L, Kastan MB, and Cho KR (1994). p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc Natl Acad Sci USA 91, 5320-5324.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 5320-5324
-
-
Slebos, R.J.C.1
Lee, M.H.2
Plunkett, B.S.3
Kessis, T.D.4
Williams, B.O.5
Jacks, T.6
Hedrick, L.7
Kastan, M.B.8
Cho, K.R.9
-
73
-
-
0027405704
-
Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
-
Church SL, Grant JW, Ridnour LA, Oberley LW, Swanson PE, Meltzer PS, and Trent JM (1993). Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc Natl Acad Sci USA 90, 3113-3117.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3113-3117
-
-
Church, S.L.1
Grant, J.W.2
Ridnour, L.A.3
Oberley, L.W.4
Swanson, P.E.5
Meltzer, P.S.6
Trent, J.M.7
-
74
-
-
0021964203
-
Prooxidant states and tumor promotion
-
Cerutti PA (1985). Prooxidant states and tumor promotion. Science 227, 375-381.
-
(1985)
Science
, vol.227
, pp. 375-381
-
-
Cerutti, P.A.1
-
75
-
-
0004707849
-
Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate
-
Borek C, and Troll W (1983). Modifiers of free radicals inhibit in vitro the oncogenic actions of x-rays, bleomycin, and the tumor promoter 12-O-tetradecanoylphorbol 13-acetate. Proc Natl Acad Sci U S A 80, 1304-1307.
-
(1983)
Proc Natl Acad Sci U S A
, vol.80
, pp. 1304-1307
-
-
Borek, C.1
Troll, W.2
-
76
-
-
0020530692
-
Inhibition of tumor promotion by a biomimetic superoxide dismutase
-
Kensler TW, Bush DM, and Kozumbo WJ (1983). Inhibition of tumor promotion by a biomimetic superoxide dismutase. Science 221, 75-77.
-
(1983)
Science
, vol.221
, pp. 75-77
-
-
Kensler, T.W.1
Bush, D.M.2
Kozumbo, W.J.3
-
77
-
-
0028233494
-
Hydrogen peroxide mediates amyloid β protein toxicity
-
Behl C, Davis JB, Lesley R, and Schubert D (1994). Hydrogen peroxide mediates amyloid β protein toxicity. Cell 77, 817-827.
-
(1994)
Cell
, vol.77
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
78
-
-
0030024241
-
Role of p21 in prostaglandin A2-mediated cellular arrest and death
-
Gorospe M, and Holbrook NJ (1996). Role of p21 in prostaglandin A2-mediated cellular arrest and death. Cancer Res 56, 475-479.
-
(1996)
Cancer Res
, vol.56
, pp. 475-479
-
-
Gorospe, M.1
Holbrook, N.J.2
-
79
-
-
0029956387
-
Wat1/Cip1 against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells
-
Wat1/Cip1 against prostaglandin A2-mediated apoptosis of human colorectal carcinoma cells. Mol Cell Biol 16, 6654-6660.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 6654-6660
-
-
Gorospe, M.1
Wang, X.2
Guyton, K.Z.3
Holbrook, N.J.4
-
80
-
-
0029916932
-
Waf1 is required for survival of differentiating neuroblastoma cells
-
Waf1 is required for survival of differentiating neuroblastoma cells. Mol Cell Biol 16, 1335-1341.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1335-1341
-
-
Poluha, W.1
Poluha, D.K.2
Chang, B.3
Crosbie, N.E.4
Schonhoff, C.M.5
Kilpatrick, D.L.6
Ross, A.H.7
-
81
-
-
0032510026
-
Waf1/Cip1/Sdi1 lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells
-
Waf1/Cip1/Sdi1 lacking CDK-inhibitory activity fails to prevent apoptosis in human colorectal carcinoma cells. Oncogene 16, 705-712.
-
(1998)
Oncogene
, vol.16
, pp. 705-712
-
-
Lu, Y.1
Yamagishi, N.2
Yagi, T.3
Takebe, H.4
-
82
-
-
0024312892
-
Rapid detection of ras oncogenes in human tumors: Applications to colon, esophageal, and gastric cancer
-
Jiang W, Kahn SM, Guillem JG, Lu S-H, and Weinstein IB (1989). Rapid detection of ras oncogenes in human tumors: applications to colon, esophageal, and gastric cancer. Oncogene 4, 923-928.
-
(1989)
Oncogene
, vol.4
, pp. 923-928
-
-
Jiang, W.1
Kahn, S.M.2
Guillem, J.G.3
Lu, S.-H.4
Weinstein, I.B.5
-
83
-
-
0020624456
-
Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations
-
Capon DJ, Seeburg PH, McGrath JP, Hayflick JS, Edman U, Levinson AD, and Goeddel DV (1983). Activation of Ki-ras2 gene In human colon and lung carcinomas by two different point mutations. Nature 304, 507-513.
-
(1983)
Nature
, vol.304
, pp. 507-513
-
-
Capon, D.J.1
Seeburg, P.H.2
McGrath, J.P.3
Hayflick, J.S.4
Edman, U.5
Levinson, A.D.6
Goeddel, D.V.7
-
84
-
-
0031930688
-
Modulation of cell death by Bcl-XL through caspase interaction
-
Clem RJ, Cheng EH, Karp CL, Kirsch DG, Ueno K, Takahashi A, Kastan MB, Griffin DE, Earnshaw WC, Veliuona MA, and Hardwick JM (1998). Modulation of cell death by Bcl-XL through caspase interaction. Proc Natl Acad Sci USA 95, 554-559.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 554-559
-
-
Clem, R.J.1
Cheng, E.H.2
Karp, C.L.3
Kirsch, D.G.4
Ueno, K.5
Takahashi, A.6
Kastan, M.B.7
Griffin, D.E.8
Earnshaw, W.C.9
Veliuona, M.A.10
Hardwick, J.M.11
-
85
-
-
0031465443
-
Conversion of Bcl-2 to a Bax-like death effector by caspases
-
Cheng EH-Y, Kirsch DG, Clem RJ, Ravi R, Kastan MB, Bedi A, Ueno K, and Hardwick JM (1997). Conversion of Bcl-2 to a Bax-like death effector by caspases. Science 278, 1966-1968.
-
(1997)
Science
, vol.278
, pp. 1966-1968
-
-
Cheng, E.H.-Y.1
Kirsch, D.G.2
Clem, R.J.3
Ravi, R.4
Kastan, M.B.5
Bedi, A.6
Ueno, K.7
Hardwick, J.M.8
-
86
-
-
0020561660
-
Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye
-
Bernai SD, Lampidis TJ, McIsaac RM, and Chen LB (1983). Anticarcinoma activity in vivo of rhodamine 123, a mitochondrial-specific dye. Science 222, 169-172.
-
(1983)
Science
, vol.222
, pp. 169-172
-
-
Bernai, S.D.1
Lampidis, T.J.2
McIsaac, R.M.3
Chen, L.B.4
-
87
-
-
0020003209
-
Interactions of rhodamine 123 with living cells studied by flow cytometry
-
Darzynkiewicz Z, Traganos F, Staiano-Coico L, Kapuscinski J, and Melamed MR (1982). Interactions of rhodamine 123 with living cells studied by flow cytometry. Cancer Res 42, 799-806.
-
(1982)
Cancer Res
, vol.42
, pp. 799-806
-
-
Darzynkiewicz, Z.1
Traganos, F.2
Staiano-Coico, L.3
Kapuscinski, J.4
Melamed, M.R.5
-
88
-
-
0020060701
-
Decreased uptake and retention of rhodamine 123 by mitochondria in feline sarcoma virus-transformed mink cells
-
Johnson LV, Summerhayes IC, and Chen LB (1982). Decreased uptake and retention of rhodamine 123 by mitochondria in feline sarcoma virus-transformed mink cells. Cell 28, 7-14.
-
(1982)
Cell
, vol.28
, pp. 7-14
-
-
Johnson, L.V.1
Summerhayes, I.C.2
Chen, L.B.3
-
89
-
-
0020695797
-
Selective toxicity of rhodamine 123 in carcinoma cells in vitro
-
Lampidis TJ, Bernal SD, Summerhayes IC, and Chen LB (1983). Selective toxicity of rhodamine 123 in carcinoma cells in vitro. Cancer Res 43, 716-720.
-
(1983)
Cancer Res
, vol.43
, pp. 716-720
-
-
Lampidis, T.J.1
Bernal, S.D.2
Summerhayes, I.C.3
Chen, L.B.4
-
90
-
-
0021762056
-
Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria
-
Modica-Napolitano JS, Weiss MJ, Chen LB, and Aprille JR (1984). Rhodamine 123 inhibits bioenergetic function in isolated rat liver mitochondria. Biochem Biophys Res Commun 118, 717-723.
-
(1984)
Biochem Biophys Res Commun
, vol.118
, pp. 717-723
-
-
Modica-Napolitano, J.S.1
Weiss, M.J.2
Chen, L.B.3
Aprille, J.R.4
-
91
-
-
0020428221
-
Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro
-
Bernal SD, Lampidis TJ, Summerhayes IC, and Chen LB (1982). Rhodamine-123 selectively reduces clonal growth of carcinoma cells in vitro. Science 218, 1117-1119.
-
(1982)
Science
, vol.218
, pp. 1117-1119
-
-
Bernal, S.D.1
Lampidis, T.J.2
Summerhayes, I.C.3
Chen, L.B.4
-
92
-
-
0028605882
-
Antioxidants and carcinogenesis
-
Rautalahti M, and Huttunen J (1993). Antioxidants and carcinogenesis. Ann Med 25, 435-441.
-
(1993)
Ann Med
, vol.25
, pp. 435-441
-
-
Rautalahti, M.1
Huttunen, J.2
|