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Volumn 123, Issue 3, 2009, Pages 323-333

Prothymosin α and cell death mode switch, a novel target for the prevention of cerebral ischemia-induced damage

Author keywords

Apoptosis; Brain derived neurotrophic factor; Glia; Glucose transporter; Necrosis; Protein kinase C

Indexed keywords

ADENOSINE TRIPHOSPHATE; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BASIC FIBROBLAST GROWTH FACTOR; BIM PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEOXYRIBONUCLEASE; ERYTHROPOIETIN; FAS ANTIGEN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; NERVE GROWTH FACTOR; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROCASPASE 9; PROTEIN BAD; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN KINASE B; PROTHYMOSIN ALPHA; RECOMBINANT BRAIN DERIVED NEUROTROPHIC FACTOR; SERINE PROTEINASE OMI; TISSUE PLASMINOGEN ACTIVATOR; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 67849119416     PISSN: 01637258     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2009.05.007     Document Type: Review
Times cited : (39)

References (119)
  • 1
    • 0344076149 scopus 로고    scopus 로고
    • A controlled trial of recombinant methionyl human BDNF in ALS: the BDNF Study Group (Phase III)
    • A controlled trial of recombinant methionyl human BDNF in ALS: the BDNF Study Group (Phase III). Neurology 52 7 (1999) 1427-1433
    • (1999) Neurology , vol.52 , Issue.7 , pp. 1427-1433
  • 2
    • 0032577592 scopus 로고    scopus 로고
    • Inhibition of NMDA receptors and nitric oxide synthase reduces ischemic injury of the retina
    • Adachi K., Fujita Y., Morizane C., Akaike A., Ueda M., Satoh M., et al. Inhibition of NMDA receptors and nitric oxide synthase reduces ischemic injury of the retina. Eur J Pharmacol 350 1 (1998) 53-57
    • (1998) Eur J Pharmacol , vol.350 , Issue.1 , pp. 53-57
    • Adachi, K.1    Fujita, Y.2    Morizane, C.3    Akaike, A.4    Ueda, M.5    Satoh, M.6
  • 3
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: arbiters of cell survival
    • Adams J.M., and Cory S. The Bcl-2 protein family: arbiters of cell survival. Science 281 5381 (1998) 1322-1326
    • (1998) Science , vol.281 , Issue.5381 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 4
    • 0028233762 scopus 로고
    • A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment
    • Ando A., Yonezawa K., Gout I., Nakata T., Ueda H., Hara K., et al. A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment. EMBO J 13 13 (1994) 3033-3038
    • (1994) EMBO J , vol.13 , Issue.13 , pp. 3033-3038
    • Ando, A.1    Yonezawa, K.2    Gout, I.3    Nakata, T.4    Ueda, H.5    Hara, K.6
  • 5
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: signaling and modulation
    • Ashkenazi A., and Dixit V.M. Death receptors: signaling and modulation. Science 281 5381 (1998) 1305-1308
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 6
    • 0032892598 scopus 로고    scopus 로고
    • Potential usefulness of basic fibroblast growth factor as a treatment for stroke
    • Ay H., Ay I., Koroshetz W.J., and Finklestein S.P. Potential usefulness of basic fibroblast growth factor as a treatment for stroke. Cerebrovasc Dis 9 3 (1999) 131-135
    • (1999) Cerebrovasc Dis , vol.9 , Issue.3 , pp. 131-135
    • Ay, H.1    Ay, I.2    Koroshetz, W.J.3    Finklestein, S.P.4
  • 7
    • 0035910918 scopus 로고    scopus 로고
    • Intravenous basic fibroblast growth factor (bFGF) decreases DNA fragmentation and prevents downregulation of Bcl-2 expression in the ischemic brain following middle cerebral artery occlusion in rats
    • Ay I., Sugimori H., and Finklestein S.P. Intravenous basic fibroblast growth factor (bFGF) decreases DNA fragmentation and prevents downregulation of Bcl-2 expression in the ischemic brain following middle cerebral artery occlusion in rats. Brain Res Mol Brain Res 87 1 (2001) 71-80
    • (2001) Brain Res Mol Brain Res , vol.87 , Issue.1 , pp. 71-80
    • Ay, I.1    Sugimori, H.2    Finklestein, S.P.3
  • 8
    • 0032428331 scopus 로고    scopus 로고
    • Modulation of life and death by the TNF receptor superfamily
    • Baker S.J., and Reddy E.P. Modulation of life and death by the TNF receptor superfamily. Oncogene 17 25 (1998) 3261-3270
    • (1998) Oncogene , vol.17 , Issue.25 , pp. 3261-3270
    • Baker, S.J.1    Reddy, E.P.2
  • 10
    • 0037043823 scopus 로고    scopus 로고
    • Regulation of prothymosin alpha by estrogen receptor alpha: molecular mechanisms and relevance in estrogen-mediated breast cell growth
    • Bianco N.R., and Montano M.M. Regulation of prothymosin alpha by estrogen receptor alpha: molecular mechanisms and relevance in estrogen-mediated breast cell growth. Oncogene 21 34 (2002) 5233-5244
    • (2002) Oncogene , vol.21 , Issue.34 , pp. 5233-5244
    • Bianco, N.R.1    Montano, M.M.2
  • 11
    • 0036968150 scopus 로고    scopus 로고
    • Fiblast (trafermin) in acute stroke: results of the European-Australian phase II/III safety and efficacy trial
    • Bogousslavsky J., Victor S.J., Salinas E.O., Pallay A., Donnan G.A., Fieschi C., et al. Fiblast (trafermin) in acute stroke: results of the European-Australian phase II/III safety and efficacy trial. Cerebrovasc Dis 14 3-4 (2002) 239-251
    • (2002) Cerebrovasc Dis , vol.14 , Issue.3-4 , pp. 239-251
    • Bogousslavsky, J.1    Victor, S.J.2    Salinas, E.O.3    Pallay, A.4    Donnan, G.A.5    Fieschi, C.6
  • 12
    • 0141724805 scopus 로고    scopus 로고
    • A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia
    • Borsello T., Clarke P.G., Hirt L., Vercelli A., Repici M., Schorderet D.F., et al. A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia. Nat Med 9 9 (2003) 1180-1186
    • (2003) Nat Med , vol.9 , Issue.9 , pp. 1180-1186
    • Borsello, T.1    Clarke, P.G.2    Hirt, L.3    Vercelli, A.4    Repici, M.5    Schorderet, D.F.6
  • 13
    • 0034641710 scopus 로고    scopus 로고
    • Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury
    • Brines M.L., Ghezzi P., Keenan S., Agnello D., de Lanerolle N.C., Cerami C., et al. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proc Natl Acad Sci U S A 97 19 (2000) 10526-10531
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.19 , pp. 10526-10531
    • Brines, M.L.1    Ghezzi, P.2    Keenan, S.3    Agnello, D.4    de Lanerolle, N.C.5    Cerami, C.6
  • 14
    • 0141632952 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons
    • Burkhalter J., Fiumelli H., Allaman I., Chatton J.Y., and Martin J.L. Brain-derived neurotrophic factor stimulates energy metabolism in developing cortical neurons. J Neurosci 23 23 (2003) 8212-8220
    • (2003) J Neurosci , vol.23 , Issue.23 , pp. 8212-8220
    • Burkhalter, J.1    Fiumelli, H.2    Allaman, I.3    Chatton, J.Y.4    Martin, J.L.5
  • 15
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: a beautiful pathway
    • Chen G., and Goeddel D.V. TNF-R1 signaling: a beautiful pathway. Science 296 5573 (2002) 1634-1635
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 16
    • 0842342610 scopus 로고    scopus 로고
    • Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling
    • Chen D., and Zhou Q. Caspase cleavage of BimEL triggers a positive feedback amplification of apoptotic signaling. Proc Natl Acad Sci U S A 101 5 (2004) 1235-1240
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.5 , pp. 1235-1240
    • Chen, D.1    Zhou, Q.2
  • 17
    • 0032080673 scopus 로고    scopus 로고
    • Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury
    • Cheng Y., Deshmukh M., D'Costa A., Demaro J.A., Gidday J.M., Shah A., et al. Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxic-ischemic brain injury. J Clin Invest 101 9 (1998) 1992-1999
    • (1998) J Clin Invest , vol.101 , Issue.9 , pp. 1992-1999
    • Cheng, Y.1    Deshmukh, M.2    D'Costa, A.3    Demaro, J.A.4    Gidday, J.M.5    Shah, A.6
  • 20
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: roles in cell survival and oncogenesis
    • Cory S., Huang D.C., and Adams J.M. The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22 53 (2003) 8590-8607
    • (2003) Oncogene , vol.22 , Issue.53 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.2    Adams, J.M.3
  • 21
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: critical control points
    • Danial N.N., and Korsmeyer S.J. Cell death: critical control points. Cell 116 2 (2004) 205-219
    • (2004) Cell , vol.116 , Issue.2 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 22
    • 0037312886 scopus 로고    scopus 로고
    • Inflammatory mechanisms after ischemia and stroke
    • Danton G.H., and Dietrich W.D. Inflammatory mechanisms after ischemia and stroke. J Neuropathol Exp Neurol 62 2 (2003) 127-136
    • (2003) J Neuropathol Exp Neurol , vol.62 , Issue.2 , pp. 127-136
    • Danton, G.H.1    Dietrich, W.D.2
  • 23
    • 0028327655 scopus 로고
    • Intrinsic programmes of growth and survival in developing vertebrate neurons
    • Davies A.M. Intrinsic programmes of growth and survival in developing vertebrate neurons. Trends Neurosci 17 5 (1994) 195-199
    • (1994) Trends Neurosci , vol.17 , Issue.5 , pp. 195-199
    • Davies, A.M.1
  • 24
    • 0036260052 scopus 로고    scopus 로고
    • Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells
    • Diaz-Horta O., Kamagate A., Herchuelz A., and Van Eylen F. Na/Ca exchanger overexpression induces endoplasmic reticulum-related apoptosis and caspase-12 activation in insulin-releasing BRIN-BD11 cells. Diabetes 51 6 (2002) 1815-1824
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1815-1824
    • Diaz-Horta, O.1    Kamagate, A.2    Herchuelz, A.3    Van Eylen, F.4
  • 25
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic stroke: an integrated view
    • Dirnagl U., Iadecola C., and Moskowitz M.A. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci 22 9 (1999) 391-397
    • (1999) Trends Neurosci , vol.22 , Issue.9 , pp. 391-397
    • Dirnagl, U.1    Iadecola, C.2    Moskowitz, M.A.3
  • 26
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C., Fang M., Li Y., Li L., and Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 102 1 (2000) 33-42
    • (2000) Cell , vol.102 , Issue.1 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 27
  • 28
    • 7744235672 scopus 로고    scopus 로고
    • Death by design: apoptosis, necrosis and autophagy
    • Edinger A.L., and Thompson C.B. Death by design: apoptosis, necrosis and autophagy. Curr Opin Cell Biol 16 6 (2004) 663-669
    • (2004) Curr Opin Cell Biol , vol.16 , Issue.6 , pp. 663-669
    • Edinger, A.L.1    Thompson, C.B.2
  • 29
    • 0030915587 scopus 로고    scopus 로고
    • Intracellular ATP levels determine cell death fate by apoptosis or necrosis
    • Eguchi Y., Shimizu S., and Tsujimoto Y. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res 57 10 (1997) 1835-1840
    • (1997) Cancer Res , vol.57 , Issue.10 , pp. 1835-1840
    • Eguchi, Y.1    Shimizu, S.2    Tsujimoto, Y.3
  • 30
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari M., Sakahira H., Yokoyama H., Okawa K., Iwamatsu A., and Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 391 6662 (1998) 43-50
    • (1998) Nature , vol.391 , Issue.6662 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 31
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G., and Littlewood T. A matter of life and cell death. Science 281 5381 (1998) 1317-1322
    • (1998) Science , vol.281 , Issue.5381 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 32
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri K.F., and Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 3 11 (2001) E255-263
    • (2001) Nat Cell Biol , vol.3 , Issue.11
    • Ferri, K.F.1    Kroemer, G.2
  • 33
    • 0348038753 scopus 로고    scopus 로고
    • Protein kinase C-mediated cell death mode switch induced by high glucose
    • Fujita R., and Ueda H. Protein kinase C-mediated cell death mode switch induced by high glucose. Cell Death Differ 10 12 (2003) 1336-1347
    • (2003) Cell Death Differ , vol.10 , Issue.12 , pp. 1336-1347
    • Fujita, R.1    Ueda, H.2
  • 34
    • 0038156063 scopus 로고    scopus 로고
    • Protein kinase C-mediated necrosis-apoptosis switch of cortical neurons by conditioned medium factors secreted under the serum-free stress
    • Fujita R., and Ueda H. Protein kinase C-mediated necrosis-apoptosis switch of cortical neurons by conditioned medium factors secreted under the serum-free stress. Cell Death Differ 10 7 (2003) 782-790
    • (2003) Cell Death Differ , vol.10 , Issue.7 , pp. 782-790
    • Fujita, R.1    Ueda, H.2
  • 35
    • 34548809235 scopus 로고    scopus 로고
    • Prothymosin-alpha1 prevents necrosis and apoptosis following stroke
    • Fujita R., and Ueda H. Prothymosin-alpha1 prevents necrosis and apoptosis following stroke. Cell Death Differ 14 10 (2007) 1839-1842
    • (2007) Cell Death Differ , vol.14 , Issue.10 , pp. 1839-1842
    • Fujita, R.1    Ueda, H.2
  • 36
    • 58249114977 scopus 로고    scopus 로고
    • Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition
    • Fujita R., Ueda M., Fujiwara K., and Ueda H. Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition. Cell Death Differ 16 2 (2009) 349-358
    • (2009) Cell Death Differ , vol.16 , Issue.2 , pp. 349-358
    • Fujita, R.1    Ueda, M.2    Fujiwara, K.3    Ueda, H.4
  • 37
    • 0035661903 scopus 로고    scopus 로고
    • Cell density-dependent death mode switch of cultured cortical neurons under serum-free starvation stress
    • Fujita R., Yoshida A., Mizuno K., and Ueda H. Cell density-dependent death mode switch of cultured cortical neurons under serum-free starvation stress. Cell Mol Neurobiol 21 4 (2001) 317-324
    • (2001) Cell Mol Neurobiol , vol.21 , Issue.4 , pp. 317-324
    • Fujita, R.1    Yoshida, A.2    Mizuno, K.3    Ueda, H.4
  • 39
    • 0036262303 scopus 로고    scopus 로고
    • Antioxidant therapy in acute central nervous system injury: current state
    • Gilgun-Sherki Y., Rosenbaum Z., Melamed E., and Offen D. Antioxidant therapy in acute central nervous system injury: current state. Pharmacol Rev 54 2 (2002) 271-284
    • (2002) Pharmacol Rev , vol.54 , Issue.2 , pp. 271-284
    • Gilgun-Sherki, Y.1    Rosenbaum, Z.2    Melamed, E.3    Offen, D.4
  • 40
    • 0036330007 scopus 로고    scopus 로고
    • Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions
    • Gladstone D.J., Black S.E., and Hakim A.M. Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions. Stroke 33 8 (2002) 2123-2136
    • (2002) Stroke , vol.33 , Issue.8 , pp. 2123-2136
    • Gladstone, D.J.1    Black, S.E.2    Hakim, A.M.3
  • 41
    • 35348937551 scopus 로고    scopus 로고
    • Function of prothymosin alpha in chromatin decondensation and expression of thymosin beta-4 linked to angiogenesis and synaptic plasticity
    • Gomez-Marquez J. Function of prothymosin alpha in chromatin decondensation and expression of thymosin beta-4 linked to angiogenesis and synaptic plasticity. Ann N Y Acad Sci 1112 (2007) 201-209
    • (2007) Ann N Y Acad Sci , vol.1112 , pp. 201-209
    • Gomez-Marquez, J.1
  • 42
    • 2442482810 scopus 로고    scopus 로고
    • Autophagy as a cell death and tumor suppressor mechanism
    • Gozuacik D., and Kimchi A. Autophagy as a cell death and tumor suppressor mechanism. Oncogene 23 16 (2004) 2891-2906
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2891-2906
    • Gozuacik, D.1    Kimchi, A.2
  • 43
  • 44
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green D.R., and Reed J.C. Mitochondria and apoptosis. Science 281 5381 (1998) 1309-1312
    • (1998) Science , vol.281 , Issue.5381 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 45
    • 0034738054 scopus 로고    scopus 로고
    • Serum-free induced neuronal apoptosis-like cell death is independent of caspase activity
    • Hamabe W., Fukushima N., Yoshida A., and Ueda H. Serum-free induced neuronal apoptosis-like cell death is independent of caspase activity. Brain Res Mol Brain Res 78 1-2 (2000) 186-191
    • (2000) Brain Res Mol Brain Res , vol.78 , Issue.1-2 , pp. 186-191
    • Hamabe, W.1    Fukushima, N.2    Yoshida, A.3    Ueda, H.4
  • 48
    • 0022486717 scopus 로고
    • Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections
    • Hefti F. Nerve growth factor promotes survival of septal cholinergic neurons after fimbrial transections. J Neurosci 6 8 (1986) 2155-2162
    • (1986) J Neurosci , vol.6 , Issue.8 , pp. 2155-2162
    • Hefti, F.1
  • 49
    • 0027318116 scopus 로고
    • Neurotrophins promote motor neuron survival and are present in embryonic limb bud
    • Henderson C.E., Camu W., Mettling C., Gouin A., Poulsen K., Karihaloo M., et al. Neurotrophins promote motor neuron survival and are present in embryonic limb bud. Nature 363 6426 (1993) 266-270
    • (1993) Nature , vol.363 , Issue.6426 , pp. 266-270
    • Henderson, C.E.1    Camu, W.2    Mettling, C.3    Gouin, A.4    Poulsen, K.5    Karihaloo, M.6
  • 51
    • 0034927081 scopus 로고    scopus 로고
    • Neurotrophins: roles in neuronal development and function
    • Huang E.J., and Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annu Rev Neurosci 24 (2001) 677-736
    • (2001) Annu Rev Neurosci , vol.24 , pp. 677-736
    • Huang, E.J.1    Reichardt, L.F.2
  • 52
    • 0037428217 scopus 로고    scopus 로고
    • Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway
    • Jiang X., Kim H.E., Shu H., Zhao Y., Zhang H., Kofron J., et al. Distinctive roles of PHAP proteins and prothymosin-alpha in a death regulatory pathway. Science 299 5604 (2003) 223-226
    • (2003) Science , vol.299 , Issue.5604 , pp. 223-226
    • Jiang, X.1    Kim, H.E.2    Shu, H.3    Zhao, Y.4    Zhang, H.5    Kofron, J.6
  • 53
    • 0034044227 scopus 로고    scopus 로고
    • Neurotrophin signal transduction in the nervous system
    • Kaplan D.R., and Miller F.D. Neurotrophin signal transduction in the nervous system. Curr Opin Neurobiol 10 3 (2000) 381-391
    • (2000) Curr Opin Neurobiol , vol.10 , Issue.3 , pp. 381-391
    • Kaplan, D.R.1    Miller, F.D.2
  • 54
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F., Wyllie A.H., and Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26 4 (1972) 239-257
    • (1972) Br J Cancer , vol.26 , Issue.4 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 55
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nat Med 3 6 (1997) 614-620
    • (1997) Nat Med , vol.3 , Issue.6 , pp. 614-620
    • Kroemer, G.1
  • 57
    • 33745761474 scopus 로고    scopus 로고
    • Microglia in cerebral ischemia: molecular actions and interactions
    • Lai A.Y., and Todd K.G. Microglia in cerebral ischemia: molecular actions and interactions. Can J Physiol Pharmacol 84 1 (2006) 49-59
    • (2006) Can J Physiol Pharmacol , vol.84 , Issue.1 , pp. 49-59
    • Lai, A.Y.1    Todd, K.G.2
  • 58
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis
    • Leist M., Single B., Castoldi A.F., Kuhnle S., and Nicotera P. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J Exp Med 185 8 (1997) 1481-1486
    • (1997) J Exp Med , vol.185 , Issue.8 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 59
    • 25144506835 scopus 로고    scopus 로고
    • Autophagy in cell death: an innocent convict?
    • Levine B., and Yuan J. Autophagy in cell death: an innocent convict?. J Clin Invest 115 10 (2005) 2679-2688
    • (2005) J Clin Invest , vol.115 , Issue.10 , pp. 2679-2688
    • Levine, B.1    Yuan, J.2
  • 60
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • Li L.Y., Luo X., and Wang X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412 6842 (2001) 95-99
    • (2001) Nature , vol.412 , Issue.6842 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 61
    • 0032845121 scopus 로고    scopus 로고
    • Ischemic cell death in brain neurons
    • Lipton P. Ischemic cell death in brain neurons. Physiol Rev 79 4 (1999) 1431-1568
    • (1999) Physiol Rev , vol.79 , Issue.4 , pp. 1431-1568
    • Lipton, P.1
  • 62
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
    • Liu X., Kim C.N., Yang J., Jemmerson R., and Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86 1 (1996) 147-157
    • (1996) Cell , vol.86 , Issue.1 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 63
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X., Budihardjo I., Zou H., Slaughter C., and Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94 4 (1998) 481-490
    • (1998) Cell , vol.94 , Issue.4 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 64
    • 0024254888 scopus 로고
    • Susceptibility of mitochondrial membranes to calcium and reactive oxygen species: implications for ischemic and toxic tissue damage
    • Malis C.D., and Bonventre J.V. Susceptibility of mitochondrial membranes to calcium and reactive oxygen species: implications for ischemic and toxic tissue damage. Prog Clin Biol Res 282 (1988) 235-259
    • (1988) Prog Clin Biol Res , vol.282 , pp. 235-259
    • Malis, C.D.1    Bonventre, J.V.2
  • 65
    • 0033842610 scopus 로고    scopus 로고
    • Prothymosin alpha selectively enhances estrogen receptor transcriptional activity by interacting with a repressor of estrogen receptor activity
    • Martini P.G., Delage-Mourroux R., Kraichely D.M., and Katzenellenbogen B.S. Prothymosin alpha selectively enhances estrogen receptor transcriptional activity by interacting with a repressor of estrogen receptor activity. Mol Cell Biol 20 17 (2000) 6224-6232
    • (2000) Mol Cell Biol , vol.20 , Issue.17 , pp. 6224-6232
    • Martini, P.G.1    Delage-Mourroux, R.2    Kraichely, D.M.3    Katzenellenbogen, B.S.4
  • 66
    • 0035235419 scopus 로고    scopus 로고
    • Breaking the mitochondrial barrier
    • Martinou J.C., and Green D.R. Breaking the mitochondrial barrier. Nat Rev Mol Cell Biol 2 1 (2001) 63-67
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.1 , pp. 63-67
    • Martinou, J.C.1    Green, D.R.2
  • 67
    • 33745641521 scopus 로고    scopus 로고
    • Evidence for serum-deprivation-induced co-release of FGF-1 and S100A13 from astrocytes
    • Matsunaga H., and Ueda H. Evidence for serum-deprivation-induced co-release of FGF-1 and S100A13 from astrocytes. Neurochem Int 49 3 (2006) 294-303
    • (2006) Neurochem Int , vol.49 , Issue.3 , pp. 294-303
    • Matsunaga, H.1    Ueda, H.2
  • 68
    • 33745094737 scopus 로고    scopus 로고
    • 2+ channel activity regulates the interaction between FGF-1 and S100A13 for stress-induced non-vesicular release
    • 2+ channel activity regulates the interaction between FGF-1 and S100A13 for stress-induced non-vesicular release. Cell Mol Neurobiol 26 3 (2006) 237-246
    • (2006) Cell Mol Neurobiol , vol.26 , Issue.3 , pp. 237-246
    • Matsunaga, H.1    Ueda, H.2
  • 69
    • 0034746288 scopus 로고    scopus 로고
    • NF-kappaB in neuronal plasticity and neurodegenerative disorders
    • Mattson M.P., and Camandola S. NF-kappaB in neuronal plasticity and neurodegenerative disorders. J Clin Invest 107 3 (2001) 247-254
    • (2001) J Clin Invest , vol.107 , Issue.3 , pp. 247-254
    • Mattson, M.P.1    Camandola, S.2
  • 70
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S. Apoptosis by death factor. Cell 88 3 (1997) 355-365
    • (1997) Cell , vol.88 , Issue.3 , pp. 355-365
    • Nagata, S.1
  • 71
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa T., Zhu H., Morishima N., Li E., Xu J., Yankner B.A., et al. Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403 6765 (2000) 98-103
    • (2000) Nature , vol.403 , Issue.6765 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6
  • 72
    • 1642442424 scopus 로고    scopus 로고
    • Microglia: neuroprotective and neurotrophic cells in the central nervous system
    • Nakajima K., and Kohsaka S. Microglia: neuroprotective and neurotrophic cells in the central nervous system. Curr Drug Targets Cardiovasc Haematol Disord 4 1 (2004) 65-84
    • (2004) Curr Drug Targets Cardiovasc Haematol Disord , vol.4 , Issue.1 , pp. 65-84
    • Nakajima, K.1    Kohsaka, S.2
  • 74
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H., Matsuzawa A., Tobiume K., Saegusa K., Takeda K., Inoue K., et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16 11 (2002) 1345-1355
    • (2002) Genes Dev , vol.16 , Issue.11 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6
  • 76
    • 0026512910 scopus 로고
    • Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report)
    • Olson L., Nordberg A., von Holst H., Backman L., Ebendal T., Alafuzoff I., et al. Nerve growth factor affects 11C-nicotine binding, blood flow, EEG, and verbal episodic memory in an Alzheimer patient (case report). J Neural Transm Park Dis Dement Sect 4 1 (1992) 79-95
    • (1992) J Neural Transm Park Dis Dement Sect , vol.4 , Issue.1 , pp. 79-95
    • Olson, L.1    Nordberg, A.2    von Holst, H.3    Backman, L.4    Ebendal, T.5    Alafuzoff, I.6
  • 77
    • 0022452419 scopus 로고
    • Two types of complementary DNAs of rat brain protein kinase C. Heterogeneity determined by alternative splicing
    • Ono Y., Kurokawa T., Fujii T., Kawahara K., Igarashi K., Kikkawa U., et al. Two types of complementary DNAs of rat brain protein kinase C. Heterogeneity determined by alternative splicing. FEBS Lett 206 2 (1986) 347-352
    • (1986) FEBS Lett , vol.206 , Issue.2 , pp. 347-352
    • Ono, Y.1    Kurokawa, T.2    Fujii, T.3    Kawahara, K.4    Igarashi, K.5    Kikkawa, U.6
  • 78
    • 0035369840 scopus 로고    scopus 로고
    • Trk receptors: mediators of neurotrophin action
    • Patapoutian A., and Reichardt L.F. Trk receptors: mediators of neurotrophin action. Curr Opin Neurobiol 11 3 (2001) 272-280
    • (2001) Curr Opin Neurobiol , vol.11 , Issue.3 , pp. 272-280
    • Patapoutian, A.1    Reichardt, L.F.2
  • 79
    • 0035129504 scopus 로고    scopus 로고
    • Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke
    • Paul R., Zhang Z.G., Eliceiri B.P., Jiang Q., Boccia A.D., Zhang R.L., et al. Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke. Nat Med 7 2 (2001) 222-227
    • (2001) Nat Med , vol.7 , Issue.2 , pp. 222-227
    • Paul, R.1    Zhang, Z.G.2    Eliceiri, B.P.3    Jiang, Q.4    Boccia, A.D.5    Zhang, R.L.6
  • 80
    • 0033783289 scopus 로고    scopus 로고
    • Fifteen years of prothymosin alpha: contradictory past and new horizons
    • Pineiro A., Cordero O.J., and Nogueira M. Fifteen years of prothymosin alpha: contradictory past and new horizons. Peptides 21 9 (2000) 1433-1446
    • (2000) Peptides , vol.21 , Issue.9 , pp. 1433-1446
    • Pineiro, A.1    Cordero, O.J.2    Nogueira, M.3
  • 81
    • 0035169898 scopus 로고    scopus 로고
    • Identification of receptors for prothymosin alpha on human lymphocytes
    • Pineiro A., Begona Bugia M., Pilar Arias M., Cordero O.J., and Nogueira M. Identification of receptors for prothymosin alpha on human lymphocytes. Biol Chem 382 10 (2001) 1473-1482
    • (2001) Biol Chem , vol.382 , Issue.10 , pp. 1473-1482
    • Pineiro, A.1    Begona Bugia, M.2    Pilar Arias, M.3    Cordero, O.J.4    Nogueira, M.5
  • 82
    • 0026504147 scopus 로고
    • Social controls on cell survival and cell death
    • Raff M.C. Social controls on cell survival and cell death. Nature 356 6368 (1992) 397-400
    • (1992) Nature , vol.356 , Issue.6368 , pp. 397-400
    • Raff, M.C.1
  • 83
    • 0033579301 scopus 로고    scopus 로고
    • Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
    • Riccio A., Ahn S., Davenport C.M., Blendy J.A., and Ginty D.D. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286 5448 (1999) 2358-2361
    • (1999) Science , vol.286 , Issue.5448 , pp. 2358-2361
    • Riccio, A.1    Ahn, S.2    Davenport, C.M.3    Blendy, J.A.4    Ginty, D.D.5
  • 84
    • 0030612602 scopus 로고    scopus 로고
    • Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor
    • Rodeck U., Jost M., DuHadaway J., Kari C., Jensen P.J., Risse B., et al. Regulation of Bcl-xL expression in human keratinocytes by cell-substratum adhesion and the epidermal growth factor receptor. Proc Natl Acad Sci U S A 94 10 (1997) 5067-5072
    • (1997) Proc Natl Acad Sci U S A , vol.94 , Issue.10 , pp. 5067-5072
    • Rodeck, U.1    Jost, M.2    DuHadaway, J.3    Kari, C.4    Jensen, P.J.5    Risse, B.6
  • 85
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira H., Enari M., and Nagata S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391 6662 (1998) 96-99
    • (1998) Nature , vol.391 , Issue.6662 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 86
    • 22544483863 scopus 로고    scopus 로고
    • Prothymosin alpha-receptor associates with lipid rafts in PHA-stimulated lymphocytes
    • Salgado F.J., Pineiro A., Canda-Sanchez A., Lojo J., and Nogueira M. Prothymosin alpha-receptor associates with lipid rafts in PHA-stimulated lymphocytes. Mol Membr Biol 22 3 (2005) 163-176
    • (2005) Mol Membr Biol , vol.22 , Issue.3 , pp. 163-176
    • Salgado, F.J.1    Pineiro, A.2    Canda-Sanchez, A.3    Lojo, J.4    Nogueira, M.5
  • 87
    • 0031682631 scopus 로고    scopus 로고
    • Low-density induced apoptosis of cortical neurons is inhibited by serum factors
    • Sasaki Y., Fukushima N., Yoshida A., and Ueda H. Low-density induced apoptosis of cortical neurons is inhibited by serum factors. Cell Mol Neurobiol 18 5 (1998) 487-496
    • (1998) Cell Mol Neurobiol , vol.18 , Issue.5 , pp. 487-496
    • Sasaki, Y.1    Fukushima, N.2    Yoshida, A.3    Ueda, H.4
  • 88
    • 0014767671 scopus 로고
    • Potassium concentration and number of neurons in cultures of dissociated ganglia
    • Scott B.S., and Fisher K.C. Potassium concentration and number of neurons in cultures of dissociated ganglia. Exp Neurol 27 1 (1970) 16-22
    • (1970) Exp Neurol , vol.27 , Issue.1 , pp. 16-22
    • Scott, B.S.1    Fisher, K.C.2
  • 90
    • 33947622728 scopus 로고    scopus 로고
    • Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis
    • Shiau A.L., Chen S.Y., Chang M.Y., Su C.H., Chung S.Y., Yo Y.T., et al. Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis. J Immunol 178 7 (2007) 4688-4694
    • (2007) J Immunol , vol.178 , Issue.7 , pp. 4688-4694
    • Shiau, A.L.1    Chen, S.Y.2    Chang, M.Y.3    Su, C.H.4    Chung, S.Y.5    Yo, Y.T.6
  • 91
    • 0034724190 scopus 로고    scopus 로고
    • BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
    • Shimizu S., Konishi A., Kodama T., and Tsujimoto Y. BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Proc Natl Acad Sci U S A 97 7 (2000) 3100-3105
    • (2000) Proc Natl Acad Sci U S A , vol.97 , Issue.7 , pp. 3100-3105
    • Shimizu, S.1    Konishi, A.2    Kodama, T.3    Tsujimoto, Y.4
  • 92
    • 0034941330 scopus 로고    scopus 로고
    • Nerve growth factor signaling, neuroprotection, and neural repair
    • Sofroniew M.V., Howe C.L., and Mobley W.C. Nerve growth factor signaling, neuroprotection, and neural repair. Annu Rev Neurosci 24 (2001) 1217-1281
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1217-1281
    • Sofroniew, M.V.1    Howe, C.L.2    Mobley, W.C.3
  • 93
    • 1442359848 scopus 로고    scopus 로고
    • The interplay between the Bcl-2 family and death receptor-mediated apoptosis
    • Sprick M.R., and Walczak H. The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochim Biophys Acta 1644 2-3 (2004) 125-132
    • (2004) Biochim Biophys Acta , vol.1644 , Issue.2-3 , pp. 125-132
    • Sprick, M.R.1    Walczak, H.2
  • 94
    • 0033521741 scopus 로고    scopus 로고
    • Molecular characterization of mitochondrial apoptosis-inducing factor
    • Susin S.A., Lorenzo H.K., Zamzami N., Marzo I., Snow B.E., Brothers G.M., et al. Molecular characterization of mitochondrial apoptosis-inducing factor. Nature 397 6718 (1999) 441-446
    • (1999) Nature , vol.397 , Issue.6718 , pp. 441-446
    • Susin, S.A.1    Lorenzo, H.K.2    Zamzami, N.3    Marzo, I.4    Snow, B.E.5    Brothers, G.M.6
  • 95
    • 0034785591 scopus 로고    scopus 로고
    • A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death
    • Suzuki Y., Imai Y., Nakayama H., Takahashi K., Takio K., and Takahashi R. A serine protease, HtrA2, is released from the mitochondria and interacts with XIAP, inducing cell death. Mol Cell 8 3 (2001) 613-621
    • (2001) Mol Cell , vol.8 , Issue.3 , pp. 613-621
    • Suzuki, Y.1    Imai, Y.2    Nakayama, H.3    Takahashi, K.4    Takio, K.5    Takahashi, R.6
  • 96
    • 1842587600 scopus 로고    scopus 로고
    • Astrocyte influences on ischemic neuronal death
    • Swanson R.A., Ying W., and Kauppinen T.M. Astrocyte influences on ischemic neuronal death. Curr Mol Med 4 2 (2004) 193-205
    • (2004) Curr Mol Med , vol.4 , Issue.2 , pp. 193-205
    • Swanson, R.A.1    Ying, W.2    Kauppinen, T.M.3
  • 97
    • 33748201552 scopus 로고    scopus 로고
    • Mitochondria-targeted peptide antioxidants: novel neuroprotective agents
    • Szeto H.H. Mitochondria-targeted peptide antioxidants: novel neuroprotective agents. AAPS J 8 3 (2006) E521-531
    • (2006) AAPS J , vol.8 , Issue.3
    • Szeto, H.H.1
  • 98
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
    • Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 333 24 (1995) 1581-1587
    • (1995) N Engl J Med , vol.333 , Issue.24 , pp. 1581-1587
  • 99
    • 0036487232 scopus 로고    scopus 로고
    • Bcl-2 family of proteins: life-or-death switch in mitochondria
    • Tsujimoto Y. Bcl-2 family of proteins: life-or-death switch in mitochondria. Biosci Rep 22 1 (2002) 47-58
    • (2002) Biosci Rep , vol.22 , Issue.1 , pp. 47-58
    • Tsujimoto, Y.1
  • 100
    • 0037401562 scopus 로고    scopus 로고
    • Cell death regulation by the Bcl-2 protein family in the mitochondria
    • Tsujimoto Y. Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 195 2 (2003) 158-167
    • (2003) J Cell Physiol , vol.195 , Issue.2 , pp. 158-167
    • Tsujimoto, Y.1
  • 101
    • 0028040062 scopus 로고
    • The role of brain-derived neurotrophic factor in transient forebrain ischemia in the rat brain
    • discussion 331
    • Tsukahara T., Yonekawa Y., Tanaka K., Ohara O., Wantanabe S., Kimura T., et al. The role of brain-derived neurotrophic factor in transient forebrain ischemia in the rat brain. Neurosurgery 34 2 (1994) 323-331 discussion 331
    • (1994) Neurosurgery , vol.34 , Issue.2 , pp. 323-331
    • Tsukahara, T.1    Yonekawa, Y.2    Tanaka, K.3    Ohara, O.4    Wantanabe, S.5    Kimura, T.6
  • 102
    • 0034954428 scopus 로고    scopus 로고
    • Clinical trials in ALS: an overview
    • Turner M.R., Parton M.J., and Leigh P.N. Clinical trials in ALS: an overview. Semin Neurol 21 2 (2001) 167-175
    • (2001) Semin Neurol , vol.21 , Issue.2 , pp. 167-175
    • Turner, M.R.1    Parton, M.J.2    Leigh, P.N.3
  • 103
    • 14944355121 scopus 로고    scopus 로고
    • Cell death mode switch from necrosis to apoptosis in brain
    • Ueda H., and Fujita R. Cell death mode switch from necrosis to apoptosis in brain. Biol Pharm Bull 27 7 (2004) 950-955
    • (2004) Biol Pharm Bull , vol.27 , Issue.7 , pp. 950-955
    • Ueda, H.1    Fujita, R.2
  • 104
    • 1642416377 scopus 로고    scopus 로고
    • The cognition-enhancer nefiracetam inhibits both necrosis and apoptosis in retinal ischemic models in vitro and in vivo
    • Ueda M., Fujita R., Koji T., and Ueda H. The cognition-enhancer nefiracetam inhibits both necrosis and apoptosis in retinal ischemic models in vitro and in vivo. J Pharmacol Exp Ther 309 1 (2004) 200-207
    • (2004) J Pharmacol Exp Ther , vol.309 , Issue.1 , pp. 200-207
    • Ueda, M.1    Fujita, R.2    Koji, T.3    Ueda, H.4
  • 105
    • 33947230031 scopus 로고    scopus 로고
    • Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule in cortical neuronal cultures
    • Ueda H., Fujita R., Yoshida A., Matsunaga H., and Ueda M. Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule in cortical neuronal cultures. J Cell Biol 176 6 (2007) 853-862
    • (2007) J Cell Biol , vol.176 , Issue.6 , pp. 853-862
    • Ueda, H.1    Fujita, R.2    Yoshida, A.3    Matsunaga, H.4    Ueda, M.5
  • 106
    • 0034723235 scopus 로고    scopus 로고
    • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
    • Urano F., Wang X., Bertolotti A., Zhang Y., Chung P., Harding H.P., et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287 5453 (2000) 664-666
    • (2000) Science , vol.287 , Issue.5453 , pp. 664-666
    • Urano, F.1    Wang, X.2    Bertolotti, A.3    Zhang, Y.4    Chung, P.5    Harding, H.P.6
  • 107
    • 0033942613 scopus 로고    scopus 로고
    • BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
    • Vande Velde C., Cizeau J., Dubik D., Alimonti J., Brown T., Israels S., et al. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 20 15 (2000) 5454-5468
    • (2000) Mol Cell Biol , vol.20 , Issue.15 , pp. 5454-5468
    • Vande Velde, C.1    Cizeau, J.2    Dubik, D.3    Alimonti, J.4    Brown, T.5    Israels, S.6
  • 108
    • 0034630161 scopus 로고    scopus 로고
    • The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems
    • Walczak H., and Krammer P.H. The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems. Exp Cell Res 256 1 (2000) 58-66
    • (2000) Exp Cell Res , vol.256 , Issue.1 , pp. 58-66
    • Walczak, H.1    Krammer, P.H.2
  • 109
    • 0035787305 scopus 로고    scopus 로고
    • Intracellular organization of insulin signaling and GLUT4 translocation
    • Watson R.T., and Pessin J.E. Intracellular organization of insulin signaling and GLUT4 translocation. Recent Prog Horm Res 56 (2001) 175-193
    • (2001) Recent Prog Horm Res , vol.56 , pp. 175-193
    • Watson, R.T.1    Pessin, J.E.2
  • 110
    • 33645997012 scopus 로고    scopus 로고
    • Bridging the GAP between insulin signaling and GLUT4 translocation
    • Watson R.T., and Pessin J.E. Bridging the GAP between insulin signaling and GLUT4 translocation. Trends Biochem Sci 31 4 (2006) 215-222
    • (2006) Trends Biochem Sci , vol.31 , Issue.4 , pp. 215-222
    • Watson, R.T.1    Pessin, J.E.2
  • 111
    • 0001641539 scopus 로고
    • Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection
    • Williams L.R., Varon S., Peterson G.M., Wictorin K., Fischer W., Bjorklund A., et al. Continuous infusion of nerve growth factor prevents basal forebrain neuronal death after fimbria fornix transection. Proc Natl Acad Sci U S A 83 23 (1986) 9231-9235
    • (1986) Proc Natl Acad Sci U S A , vol.83 , Issue.23 , pp. 9231-9235
    • Williams, L.R.1    Varon, S.2    Peterson, G.M.3    Wictorin, K.4    Fischer, W.5    Bjorklund, A.6
  • 112
    • 12344336804 scopus 로고    scopus 로고
    • Neuroprotection in experimental stroke with targeted neurotrophins
    • Wu D. Neuroprotection in experimental stroke with targeted neurotrophins. NeuroRx 2 1 (2005) 120-128
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 120-128
    • Wu, D.1
  • 113
    • 0035900717 scopus 로고    scopus 로고
    • NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons
    • Yabe T., Wilson D., and Schwartz J.P. NFkappaB activation is required for the neuroprotective effects of pigment epithelium-derived factor (PEDF) on cerebellar granule neurons. J Biol Chem 276 46 (2001) 43313-43319
    • (2001) J Biol Chem , vol.276 , Issue.46 , pp. 43313-43319
    • Yabe, T.1    Wilson, D.2    Schwartz, J.P.3
  • 114
    • 22244468321 scopus 로고    scopus 로고
    • Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons
    • Yamashita T., Sawamoto K., Suzuki S., Suzuki N., Adachi K., Kawase T., et al. Blockade of interleukin-6 signaling aggravates ischemic cerebral damage in mice: possible involvement of Stat3 activation in the protection of neurons. J Neurochem 94 2 (2005) 459-468
    • (2005) J Neurochem , vol.94 , Issue.2 , pp. 459-468
    • Yamashita, T.1    Sawamoto, K.2    Suzuki, S.3    Suzuki, N.4    Adachi, K.5    Kawase, T.6
  • 115
    • 0035957929 scopus 로고    scopus 로고
    • Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
    • Yoneda T., Imaizumi K., Oono K., Yui D., Gomi F., Katayama T., et al. Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 276 17 (2001) 13935-13940
    • (2001) J Biol Chem , vol.276 , Issue.17 , pp. 13935-13940
    • Yoneda, T.1    Imaizumi, K.2    Oono, K.3    Yui, D.4    Gomi, F.5    Katayama, T.6
  • 117
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: how Pandora's box opens
    • Zamzami N., and Kroemer G. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2 1 (2001) 67-71
    • (2001) Nat Rev Mol Cell Biol , vol.2 , Issue.1 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 118
    • 0030584088 scopus 로고    scopus 로고
    • Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
    • Zha J., Harada H., Yang E., Jockel J., and Korsmeyer S.J. Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L). Cell 87 4 (1996) 619-628
    • (1996) Cell , vol.87 , Issue.4 , pp. 619-628
    • Zha, J.1    Harada, H.2    Yang, E.3    Jockel, J.4    Korsmeyer, S.J.5
  • 119
    • 29944438881 scopus 로고    scopus 로고
    • Necrotic death as a cell fate
    • Zong W.X., and Thompson C.B. Necrotic death as a cell fate. Genes Dev 20 1 (2006) 1-15
    • (2006) Genes Dev , vol.20 , Issue.1 , pp. 1-15
    • Zong, W.X.1    Thompson, C.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.