Intravenous basic fibroblast growth factor (bFGF) decreases DNA fragmentation and prevents downregulation of Bcl-2 expression in the ischemic brain following middle cerebral artery occlusion in rats

Molecular Brain Research

Volumn 87, Issue 1, 2001, Pages 71-80

  Ay, Ilknur ^a   Sugimori, Hiroshi ^a   Finklestein, Seth P ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Apoptosis; Basic fibroblast growth factor; Bcl 2; Focal ischemia

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CASPASE 3; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DNA FRAGMENT; DNA NUCLEOTIDYLEXOTRANSFERASE; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; DRUG EFFECT; HISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BRAIN CHEMISTRY; BRAIN ISCHEMIA; CASPASE 1; CASPASE 3; CASPASES; DNA FRAGMENTATION; DOWN-REGULATION; FIBROBLAST GROWTH FACTOR 2; IN SITU NICK-END LABELING; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRAVENOUS; MALE; NEURONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0035910918     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(00)00285-0     Document Type: Article

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