메뉴 건너뛰기




Volumn 178, Issue 7, 2007, Pages 4688-4694

Prothymosin α lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; COLLAGEN; CYTOKINE; GELATINASE B; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; PROTHYMOSIN ALPHA; TUMOR NECROSIS FACTOR ALPHA;

EID: 33947622728     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.178.7.4688     Document Type: Article
Times cited : (23)

References (52)
  • 1
    • 0038011833 scopus 로고    scopus 로고
    • Evolving concepts of rheumatoid arthritis
    • Firestein, G. S. 2003. Evolving concepts of rheumatoid arthritis. Nature 423: 356-361.
    • (2003) Nature , vol.423 , pp. 356-361
    • Firestein, G.S.1
  • 2
    • 0028058901 scopus 로고
    • Sustained and distinctive patterns of gene activation in synovial fibroblasts and whole synovial tissue obtained from inflammatory synovitis
    • Ritchlin, C., E. Dwyer, R. Bucala, and R. Winchester. 1994. Sustained and distinctive patterns of gene activation in synovial fibroblasts and whole synovial tissue obtained from inflammatory synovitis. Scand. J. Immunol. 40: 292-298.
    • (1994) Scand. J. Immunol , vol.40 , pp. 292-298
    • Ritchlin, C.1    Dwyer, E.2    Bucala, R.3    Winchester, R.4
  • 3
    • 0026033431 scopus 로고
    • Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts
    • Bucala, R., C. Ritchlin, R. Winchester, and A. Cerami. 1991. Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts. J. Exp. Med. 173: 569-574.
    • (1991) J. Exp. Med , vol.173 , pp. 569-574
    • Bucala, R.1    Ritchlin, C.2    Winchester, R.3    Cerami, A.4
  • 4
    • 0842348085 scopus 로고    scopus 로고
    • Anti-cytokine Ab immune therapy: Present status and perspectives
    • Zagury, D., and R. C. Gallo. 2004. Anti-cytokine Ab immune therapy: present status and perspectives. Drug Discov. Today 9: 72-81.
    • (2004) Drug Discov. Today , vol.9 , pp. 72-81
    • Zagury, D.1    Gallo, R.C.2
  • 5
    • 0033016267 scopus 로고    scopus 로고
    • Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: Comparison of efficacy in animal models with human clinical data
    • Bendele, A., T. McAbee, G. Sennello, J. Frazier, E. Chlipala, and D. McCabe. 1999. Efficacy of sustained blood levels of interleukin-1 receptor antagonist in animal models of arthritis: comparison of efficacy in animal models with human clinical data. Arthritis Rheum. 42: 498-506.
    • (1999) Arthritis Rheum , vol.42 , pp. 498-506
    • Bendele, A.1    McAbee, T.2    Sennello, G.3    Frazier, J.4    Chlipala, E.5    McCabe, D.6
  • 6
    • 12344331258 scopus 로고    scopus 로고
    • Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis
    • Jou, I. M., A. L. Shiau, S. Y. Chen, C. R. Wang, D. B. Shieh, C. S. Tsai, and C. L. Wu. 2005. Thrombospondin 1 as an effective gene therapeutic strategy in collagen-induced arthritis. Arthritis Rheum. 52: 339-344.
    • (2005) Arthritis Rheum , vol.52 , pp. 339-344
    • Jou, I.M.1    Shiau, A.L.2    Chen, S.Y.3    Wang, C.R.4    Shieh, D.B.5    Tsai, C.S.6    Wu, C.L.7
  • 7
    • 17244372754 scopus 로고    scopus 로고
    • Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation
    • Wang, C. R., S. Y. Chen, C. L. Wu, M. F. Liu, Y. T. Jin, L. Chao, and J. Chao. 2005. Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation. Arthritis Rheum. 52: 1319-1324.
    • (2005) Arthritis Rheum , vol.52 , pp. 1319-1324
    • Wang, C.R.1    Chen, S.Y.2    Wu, C.L.3    Liu, M.F.4    Jin, Y.T.5    Chao, L.6    Chao, J.7
  • 8
    • 0018394926 scopus 로고
    • The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin 1α1 and polypeptide β1 from calf thymus
    • Low, T. L., G. B. Thurman, M. McAdoo, J. McClure, J. L. Rossio, P. H. Naylor, and A. L. Goldstein. 1979. The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin 1α1 and polypeptide β1 from calf thymus. J. Biol. Chem. 254: 981-986.
    • (1979) J. Biol. Chem , vol.254 , pp. 981-986
    • Low, T.L.1    Thurman, G.B.2    McAdoo, M.3    McClure, J.4    Rossio, J.L.5    Naylor, P.H.6    Goldstein, A.L.7
  • 9
    • 0030701884 scopus 로고    scopus 로고
    • Prothymosin α promotes cell proliferation in NIH3T3 cells
    • Wu, C. L., A. L. Shiau, and C. S. Lin. 1997. Prothymosin α promotes cell proliferation in NIH3T3 cells. Life Sci. 61: 2091-2101.
    • (1997) Life Sci , vol.61 , pp. 2091-2101
    • Wu, C.L.1    Shiau, A.L.2    Lin, C.S.3
  • 12
    • 0030831307 scopus 로고    scopus 로고
    • Interleukin-2-activated killer cell activity in colorectal tumor patients: Evaluation of in vitro effects by prothymosin α1
    • Eckert, K., E. Grunberg, P. Immenschuh, F. Garbin, E. D. Kreuser, and H. R. Maurer. 1997. Interleukin-2-activated killer cell activity in colorectal tumor patients: evaluation of in vitro effects by prothymosin α1. J. Cancer Res. Clin. Oncol. 123: 420-428.
    • (1997) J. Cancer Res. Clin. Oncol , vol.123 , pp. 420-428
    • Eckert, K.1    Grunberg, E.2    Immenschuh, P.3    Garbin, F.4    Kreuser, E.D.5    Maurer, H.R.6
  • 13
    • 0033783289 scopus 로고    scopus 로고
    • Fifteen years of prothymosin α: Contradictory past and new horizons
    • Pineiro, A., O. J. Cordero, and M. Nogueira. 2000. Fifteen years of prothymosin α: contradictory past and new horizons. Peptides 21: 1433-1446.
    • (2000) Peptides , vol.21 , pp. 1433-1446
    • Pineiro, A.1    Cordero, O.J.2    Nogueira, M.3
  • 14
    • 0031015369 scopus 로고    scopus 로고
    • Novel approaches to immunotherapy using thymic peptides
    • Cordero, O. J., H. R. Maurer, and M. Nogueira. 1997. Novel approaches to immunotherapy using thymic peptides. Immunol. Today 18: 10-13.
    • (1997) Immunol. Today , vol.18 , pp. 10-13
    • Cordero, O.J.1    Maurer, H.R.2    Nogueira, M.3
  • 15
    • 0025264230 scopus 로고
    • Prothymosin-α enhances HLA-DR antigen expression on monocytes from patients with multiple sclerosis
    • Baxevanis, C. N., C. Sfagos, E. Anastasopoulos, G. J. Reclos, and M. Papamichail. 1990. Prothymosin-α enhances HLA-DR antigen expression on monocytes from patients with multiple sclerosis. J. Neuroimmunol. 27: 141-147.
    • (1990) J. Neuroimmunol , vol.27 , pp. 141-147
    • Baxevanis, C.N.1    Sfagos, C.2    Anastasopoulos, E.3    Reclos, G.J.4    Papamichail, M.5
  • 16
    • 0023632586 scopus 로고
    • Prothymosin α restores the depressed autologous and allogeneic mixed lymphocyte responses in patients with systemic lupus erythematosus
    • Baxevanis, C. N., G. J. Reclos, M. Papamichail, and G. C. Tsokos. 1987. Prothymosin α restores the depressed autologous and allogeneic mixed lymphocyte responses in patients with systemic lupus erythematosus. Immunopharmacol. Immunotoxicol. 9: 429-440.
    • (1987) Immunopharmacol. Immunotoxicol , vol.9 , pp. 429-440
    • Baxevanis, C.N.1    Reclos, G.J.2    Papamichail, M.3    Tsokos, G.C.4
  • 18
    • 0342425883 scopus 로고
    • Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia: Results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining
    • Qu, Z., C. H. Garcia, L. M. O'Rourke, S. R. Planck, M. Kohli, and J. T. Rosenbaum. 1994. Local proliferation of fibroblast-like synoviocytes contributes to synovial hyperplasia: results of proliferating cell nuclear antigen/cyclin, c-myc, and nucleolar organizer region staining. Arthritis Rheum. 37: 212-220.
    • (1994) Arthritis Rheum , vol.37 , pp. 212-220
    • Qu, Z.1    Garcia, C.H.2    O'Rourke, L.M.3    Planck, S.R.4    Kohli, M.5    Rosenbaum, J.T.6
  • 19
    • 0034203578 scopus 로고    scopus 로고
    • Cell cycle implications in the pathogenesis of rheumatoid arthritis
    • Volin, M. V., and A. E. Koch. 2000. Cell cycle implications in the pathogenesis of rheumatoid arthritis. Front. Biosci. 5: D594-D601.
    • (2000) Front. Biosci , vol.5
    • Volin, M.V.1    Koch, A.E.2
  • 20
    • 4444255659 scopus 로고    scopus 로고
    • Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis
    • Pap, T., M. Nawrath, J. Heinrich, M. Bosse, A. Baier, K. M. Hummel, P. Petrow, S. Kuchen, B. A. Michel, R. E. Gay, et al. 2004. Cooperation of Ras- and c-Myc-dependent pathways in regulating the growth and invasiveness of synovial fibroblasts in rheumatoid arthritis. Arthritis Rheum. 50: 2794-2802.
    • (2004) Arthritis Rheum , vol.50 , pp. 2794-2802
    • Pap, T.1    Nawrath, M.2    Heinrich, J.3    Bosse, M.4    Baier, A.5    Hummel, K.M.6    Petrow, P.7    Kuchen, S.8    Michel, B.A.9    Gay, R.E.10
  • 22
    • 0023427494 scopus 로고
    • Interleukin-2 production and effect of thymosin fraction 5 on interleukin-2 production in rheumatoid arthritis
    • Wolf, R. E., and V. C. Hall. 1987. Interleukin-2 production and effect of thymosin fraction 5 on interleukin-2 production in rheumatoid arthritis. J. Rheumatol. 14: 898-901.
    • (1987) J. Rheumatol , vol.14 , pp. 898-901
    • Wolf, R.E.1    Hall, V.C.2
  • 24
    • 3543140687 scopus 로고    scopus 로고
    • Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy
    • Ehrenstein, M. R., J. G. Evans, A. Singh, S. Moore, G. Warnes, D. A. Isenberg, and C. Mauri. 2004. Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNFα therapy. J. Exp. Med. 200: 277-285.
    • (2004) J. Exp. Med , vol.200 , pp. 277-285
    • Ehrenstein, M.R.1    Evans, J.G.2    Singh, A.3    Moore, S.4    Warnes, G.5    Isenberg, D.A.6    Mauri, C.7
  • 25
    • 0021613122 scopus 로고
    • Suppressor cell responses in patients with rheumatoid arthritis: The effect of thymosin
    • Zatz, M. M., J. Oliver, A. L. Goldstein, C. Novak, and R. P. Jacobs. 1984. Suppressor cell responses in patients with rheumatoid arthritis: the effect of thymosin. Thymus 6: 205-218.
    • (1984) Thymus , vol.6 , pp. 205-218
    • Zatz, M.M.1    Oliver, J.2    Goldstein, A.L.3    Novak, C.4    Jacobs, R.P.5
  • 27
    • 0035176890 scopus 로고    scopus 로고
    • Retrovirus-mediated transfer of prothymosin gene inhibits tumor growth and prolongs survival in murine bladder cancer
    • Shiau, A. L., P. R. Lin, M. Y. Chang, and C. L. Wu. 2001. Retrovirus-mediated transfer of prothymosin gene inhibits tumor growth and prolongs survival in murine bladder cancer. Gene Ther. 8: 1609-1617.
    • (2001) Gene Ther , vol.8 , pp. 1609-1617
    • Shiau, A.L.1    Lin, P.R.2    Chang, M.Y.3    Wu, C.L.4
  • 28
    • 0000693470 scopus 로고    scopus 로고
    • Construction and propagation of human adenovirus vectors
    • I. E. Celis, ed. Academic Press, San Diego, pp
    • Hitt, M., A. J. Bett, L. Prevec, and F. L. Graham. 1998. Construction and propagation of human adenovirus vectors. In Cell Biology: A Laboratory Handbook. I. E. Celis, ed. Academic Press, San Diego, pp. 479-490.
    • (1998) Cell Biology: A Laboratory Handbook , pp. 479-490
    • Hitt, M.1    Bett, A.J.2    Prevec, L.3    Graham, F.L.4
  • 29
    • 17744380971 scopus 로고    scopus 로고
    • Transgenic overexpression of prothymosin α induces development of polycystic kidney disease
    • Li, K. J., A. L. Shiau, Y. Y. Chiou, Y. T. Yo, and C. L. Wu. 2005. Transgenic overexpression of prothymosin α induces development of polycystic kidney disease. Kidney Int. 67: 1710-1722.
    • (2005) Kidney Int , vol.67 , pp. 1710-1722
    • Li, K.J.1    Shiau, A.L.2    Chiou, Y.Y.3    Yo, Y.T.4    Wu, C.L.5
  • 30
    • 0038606985 scopus 로고    scopus 로고
    • Transcriptional regulation of the human MIP-1α promoter by RUNX1 and MOZ
    • Bristow, C. A., and P. Shore. 2003. Transcriptional regulation of the human MIP-1α promoter by RUNX1 and MOZ. Nucleic Acids Res. 31: 2735-2744.
    • (2003) Nucleic Acids Res , vol.31 , pp. 2735-2744
    • Bristow, C.A.1    Shore, P.2
  • 32
    • 0035863813 scopus 로고    scopus 로고
    • IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis
    • Woods, I. M., K. I. Katschke, M. V. Volin, I. H. Ruth, D. C. Woodruff, M. A. Amin, M. A. Connors, H. Kurata, K. Arai, G. K. Haines, et al. 2001. IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis. J. Immunol. 166: 1214-1222.
    • (2001) J. Immunol , vol.166 , pp. 1214-1222
    • Woods, I.M.1    Katschke, K.I.2    Volin, M.V.3    Ruth, I.H.4    Woodruff, D.C.5    Amin, M.A.6    Connors, M.A.7    Kurata, H.8    Arai, K.9    Haines, G.K.10
  • 38
    • 0029051330 scopus 로고
    • Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis
    • Kasama, T., R. M. Stricter, N. W. Lukacs, P. M. Lincoln, M. D. Burdick, and S. L. Kunkel. 1995. Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis. J. Clin. Invest. 95: 2868-2876.
    • (1995) J. Clin. Invest , vol.95 , pp. 2868-2876
    • Kasama, T.1    Stricter, R.M.2    Lukacs, N.W.3    Lincoln, P.M.4    Burdick, M.D.5    Kunkel, S.L.6
  • 39
    • 0346220027 scopus 로고    scopus 로고
    • Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis
    • Shahrara, S., M. A. Amin, J. M. Woods, G. K. Haines, and A. E. Koch. 2003. Chemokine receptor expression and in vivo signaling pathways in the joints of rats with adjuvant-induced arthritis. Arthritis Rheum. 48: 3568-3583.
    • (2003) Arthritis Rheum , vol.48 , pp. 3568-3583
    • Shahrara, S.1    Amin, M.A.2    Woods, J.M.3    Haines, G.K.4    Koch, A.E.5
  • 40
    • 0036681846 scopus 로고    scopus 로고
    • The importance of IL-1β and TNF-α, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis
    • Kagari, T., H. Doi, and T. Shimozato. 2002. The importance of IL-1β and TNF-α, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis. J. Immunol. 169: 1459-1466.
    • (2002) J. Immunol , vol.169 , pp. 1459-1466
    • Kagari, T.1    Doi, H.2    Shimozato, T.3
  • 43
    • 0025189810 scopus 로고
    • Production of tumor necrosis factor by human osteoblasts is modulated by other cytokines, but not by osteotropic hormones
    • Gowen, M., K. Chapman, A. Littlewood, D. Hughes, D. Evans, and G. Russell. 1990. Production of tumor necrosis factor by human osteoblasts is modulated by other cytokines, but not by osteotropic hormones. Endocrinology 126: 1250-1255.
    • (1990) Endocrinology , vol.126 , pp. 1250-1255
    • Gowen, M.1    Chapman, K.2    Littlewood, A.3    Hughes, D.4    Evans, D.5    Russell, G.6
  • 44
    • 0031985831 scopus 로고    scopus 로고
    • Effects of cortisol on the expression of interleukin-6 and interleukin-1β in human osteoblast-like cells
    • Swolin-Eide, D., and C. Ohlsson. 1998. Effects of cortisol on the expression of interleukin-6 and interleukin-1β in human osteoblast-like cells. J. Endocrinol. 156: 107-114.
    • (1998) J. Endocrinol , vol.156 , pp. 107-114
    • Swolin-Eide, D.1    Ohlsson, C.2
  • 45
    • 0034956520 scopus 로고    scopus 로고
    • Blockade of the p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and interleukin-6 expression in MC3T3E-1 osteoblasts
    • Chae, H. J., S. C. Kim, S. W. Chae, N. H. An, H. H. Kim, Z. H. Lee, and H. R. Kim. 2001. Blockade of the p38 mitogen-activated protein kinase pathway inhibits inducible nitric oxide synthase and interleukin-6 expression in MC3T3E-1 osteoblasts. Pharmacol. Res. 43: 275-283.
    • (2001) Pharmacol. Res , vol.43 , pp. 275-283
    • Chae, H.J.1    Kim, S.C.2    Chae, S.W.3    An, N.H.4    Kim, H.H.5    Lee, Z.H.6    Kim, H.R.7
  • 46
    • 1242286471 scopus 로고    scopus 로고
    • Effects of physiological concentrations of steroid hormones and interleukin-11 on basal and stimulated production of interleukin-8 by human osteoblast-like cells with different functional profiles
    • Dovio, A., M. L. Sartori, R. G. Masera, L. Peretti, L. Perotti, and A. Angeli. 2004. Effects of physiological concentrations of steroid hormones and interleukin-11 on basal and stimulated production of interleukin-8 by human osteoblast-like cells with different functional profiles. Clin. Exp. Rheumatol. 22: 79-84.
    • (2004) Clin. Exp. Rheumatol , vol.22 , pp. 79-84
    • Dovio, A.1    Sartori, M.L.2    Masera, R.G.3    Peretti, L.4    Perotti, L.5    Angeli, A.6
  • 47
    • 0034015560 scopus 로고    scopus 로고
    • Human osteoblast-like cells and osteosarcoma cell lines synthesize macrophage inhibitory protein 1α in response to interleukin 1β and tumor necrosis factor α stimulation in vitro
    • Taichman, R. S., M. J. Reilly, and L. S. Matthews. 2000. Human osteoblast-like cells and osteosarcoma cell lines synthesize macrophage inhibitory protein 1α in response to interleukin 1β and tumor necrosis factor α stimulation in vitro. Br. J. Haematol. 108: 275-283.
    • (2000) Br. J. Haematol , vol.108 , pp. 275-283
    • Taichman, R.S.1    Reilly, M.J.2    Matthews, L.S.3
  • 48
    • 11144248909 scopus 로고    scopus 로고
    • The innate immune response to adenovirus vectors
    • Muruve, D. A. 2004. The innate immune response to adenovirus vectors. Hum. Gene Ther. 15: 1157-1166.
    • (2004) Hum. Gene Ther , vol.15 , pp. 1157-1166
    • Muruve, D.A.1
  • 52
    • 0027201525 scopus 로고
    • Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo
    • Tetlow, L. C., M. Lees, Y. Ogata, H. Nagase, and D. E. Woolley. 1993. Differential expression of gelatinase B (MMP-9) and stromelysin-1 (MMP-3) by rheumatoid synovial cells in vitro and in vivo. Rheumatol. Int. 13: 53-59.
    • (1993) Rheumatol. Int , vol.13 , pp. 53-59
    • Tetlow, L.C.1    Lees, M.2    Ogata, Y.3    Nagase, H.4    Woolley, D.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.