Single nucleotide polymorphism associated with mature miR-125a alters the processing of pri-miRNA

Human Molecular Genetics

Volumn 16, Issue 9, 2007, Pages 1124-1131

  Duan, Ranhui ^a   Pak, ChangHui ^a   Jin, Peng ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA;

ARTICLE; BIOGENESIS; CELL STRAIN HEK293; GENE EXPRESSION; GENE LOCATION; GENE SEQUENCE; GENE TARGETING; GENETIC ANALYSIS; GENETIC CODE; GENETIC IDENTIFICATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOLECULAR EVOLUTION; PRIORITY JOURNAL; RNA PROCESSING; RNA STRUCTURE; RNA SYNTHESIS; RNA TRANSLATION; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSLATION REGULATION;

BASE SEQUENCE; BLOTTING, NORTHERN; CELL LINE; HUMANS; MICRORNAS; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BIOSYNTHESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL;

EID: 34447319406     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddm062     Document Type: Article

References (12)

1. Plasterk R.H. (2006) Micro RNAs in animal development. Cell, 124, 877-881.
2. Zamore, P.D. and Haley, B. (2005) Ribo-gnome: The big world of small RNAs. Science, 309, 1519-1524.
3. Croce, C.M. and Calin, G.A. (2005) miRNAs, cancer, and stem cell division. Cell, 122, 6-7.
4. Lu, J., Getz, G., Miska, E.A., Alvarez-Saavedra, E., Lamb, J., Peck D., Sweet-Cordero, A., Ebert, B.L., Mak R.H., Ferrando, A.A. et al. (2005) MicroRNA expression profiles classify human cancers. Nature 435, 834-838.
5. Han, J., Lee, Y., Yeom, K.H., Nam, J.W., Heo, I., Rhee, J.K., Sohn, S.Y., Cho, Y., Zhang, B.T. and Kim, V.N. (2006) Molecular basis for the recognition of primary microRNAs by the Drosha-DGCR8 complex. Cell 125, 887-901.
6. Zuker, M. (2003) Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res., 31, 3406-3415.
7. Wu, L. and Belasco, J.G. (2005) Micro-RNA regulation of the mammalian lin-28 gene during neuronal differentiation of embryonal carcinoma cells. Mol. Cell. Biol., 25, 9198-9208.
8. Wong, K.K., deLeeuw, R.J., Dosanjh, N.S., Kimm, L.R., Cheng, Z., Horsman, D.E., MacAulay, C., Ng, R.T., Brown, C.J., Eichler, E.E. et al. (2007) A comprehensive analysis of common copy-number variations in the human genome. Am. J. Hum. Genet., 80, 91-104.
9. Law, M.E., Templeton, K.L., Kitange, G., Smith, J., Misra, A., Feuerstein, B.G. and Jenkins, R.B. (2005) Molecular cytogenetic analysis of chromosomes 1 and 19 in glioma cell lines. Cancer Genet. Cytogenet., 160, 1-14.
10. Schulman, B.R., Esquela-Kerscher, A. and Slack, F.J. (2005) Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev. Dyn., 234, 1046-1054.
11. Scott, G.K., Goga, A., Bhaumik D., Berger, C.E., Sullivan, C.S. and Benz, C.C. (2007) Coordinate suppression of ERBB2 and ERBB3 by enforced expression of micro-RNA miR-125a or miR-125b. J. Biol. Chem., 282, 1479-1486.
12. Iorio, M.V., Ferracin, M., Liu, C.G., Veronese, A., Spizzo, R., Sabbioni, S., Magri, E., Pedriali, M., Fabbri, M., Campiglio, M. et al. (2005) MicroRNA gene expression deregulation in human breast cancer. Cancer Res., 65, 7065-7070.