-
1
-
-
33749492425
-
Endoplasmic reticulum stress signaling in disease
-
DOI 10.1152/physrev.00015.2006
-
Marciniak SJ, Ron D. Endoplasmic reticulum stress signaling in disease. Physiol Rev 2006;86:1133-1149 (Pubitemid 44521649)
-
(2006)
Physiological Reviews
, vol.86
, Issue.4
, pp. 1133-1149
-
-
Marciniak, S.J.1
Ron, D.2
-
2
-
-
57049117856
-
Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
-
Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008;7:1013-1030
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 1013-1030
-
-
Kim, I.1
Xu, W.2
Reed, J.C.3
-
3
-
-
36248949141
-
The endoplasmic reticulum and the unfolded protein response
-
DOI 10.1016/j.semcdb.2007.09.003, PII S1084952107001498, Degredation of Misfolded Glycoproteins
-
Malhotra JD, Kaufman RJ. The endoplasmic reticulum and the unfolded protein response. Semin Cell Dev Biol 2007;18:716-731 (Pubitemid 350138453)
-
(2007)
Seminars in Cell and Developmental Biology
, vol.18
, Issue.6
, pp. 716-731
-
-
Malhotra, J.D.1
Kaufman, R.J.2
-
4
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001;81:807-869 (Pubitemid 32267078)
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
5
-
-
0032928614
-
Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
-
Widmann C, Gibson S, Jarpe MB, et al. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 1999;79:143-180 (Pubitemid 29056951)
-
(1999)
Physiological Reviews
, vol.79
, Issue.1
, pp. 143-180
-
-
Widmann, C.1
Gibson, S.2
Jarpe, M.B.3
Johnson, G.L.4
-
6
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
DOI 10.1126/science.275.5296.90
-
Ichijo H, Nishida E, Irie K, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997;275:90-94 • The first paper, to our knowledge, on ASK1 identification. (Pubitemid 27020316)
-
(1997)
Science
, vol.275
, Issue.5296
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
Ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
Takagi, M.7
Matsumoto, K.8
Miyazono, K.9
Gotoh, Y.10
-
7
-
-
44849124411
-
ALS-linked mutant SOD1 induces ER stress- And ASK1-dependent motor neuron death by targeting Derlin-1
-
DOI 10.1101/gad.1640108
-
Nishitoh H, Kadowaki H, Nagai A, et al. ALS-linked mutant SOD1 induces ER stress- and ASK1-dependent motor neuron death by targeting Derlin-1. Genes Dev 2008;22:1451-1464 (Pubitemid 351793080)
-
(2008)
Genes and Development
, vol.22
, Issue.11
, pp. 1451-1464
-
-
Nishitoh, H.1
Kadowaki, H.2
Nagai, A.3
Maruyama, T.4
Yokota, T.5
Fukutomi, H.6
Noguchi, T.7
Matsuzawa, A.8
Takeda, K.9
Ichijo, H.10
-
8
-
-
0036606540
-
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
-
DOI 10.1101/gad.992302
-
Nishitoh H, Matsuzawa A, Tobiume K, et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002;16:1345-1355 • The first paper, to our knowledge, about the important role of ASK1 in ER stress-induced cell death. (Pubitemid 34615088)
-
(2002)
Genes and Development
, vol.16
, Issue.11
, pp. 1345-1355
-
-
Nishitoh, H.1
Matsuzawa, A.2
Tobiume, K.3
Saegusa, K.4
Takeda, K.5
Inoue, K.6
Hori, S.7
Kakizuka, A.8
Ichijo, H.9
-
9
-
-
0033782015
-
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
-
DOI 10.1038/35014014
-
Bertolotti A, Zhang Y, Hendershot LM, et al. Dynamic interaction of BiP and ER stress transducers in the unfolded- protein response. Nat Cell Biol 2000;2:326-332 (Pubitemid 30781088)
-
(2000)
Nature Cell Biology
, vol.2
, Issue.6
, pp. 326-332
-
-
Bertolotti, A.1
Zhang, Y.2
Hendershot, L.M.3
Harding, H.P.4
Ron, D.5
-
10
-
-
30044432596
-
On the mechanism of sensing unfolded protein in the endoplasmic reticulum
-
DOI 10.1073/pnas.0509487102
-
Credle JJ, Finer-Moore JS, Papa FR, et al. On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci USA 2005;102:18773-18784 (Pubitemid 43049523)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.52
, pp. 18773-18784
-
-
Credle, J.J.1
Finer-Moore, J.S.2
Papa, F.R.3
Stroud, R.M.4
Walter, P.5
-
11
-
-
33644858343
-
The unfolded protein response: A stress signaling pathway critical for health and disease
-
PII 0000611420060124100018
-
Zhang K, Kaufman RJ. The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 2006;66:S102-9 (Pubitemid 43739994)
-
(2006)
Neurology
, vol.66
, Issue.2 SUPPL. 1
-
-
Zhang, K.1
Kaufman, R.J.2
-
12
-
-
33745893809
-
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
-
DOI 10.1126/science.1129631
-
Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006;313:104-107 (Pubitemid 44051264)
-
(2006)
Science
, vol.313
, Issue.5783
, pp. 104-107
-
-
Hollien, J.1
Weissman, J.S.2
-
13
-
-
33751333201
-
Substrate-Specific Translocational Attenuation during ER Stress Defines a Pre-Emptive Quality Control Pathway
-
DOI 10.1016/j.cell.2006.10.032, PII S0092867406014103
-
Kang SW, Rane NS, Kim SJ, et al. Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell 2006;127:999-1013 (Pubitemid 44803063)
-
(2006)
Cell
, vol.127
, Issue.5
, pp. 999-1013
-
-
Kang, S.-W.1
Rane, N.S.2
Kim, S.J.3
Garrison, J.L.4
Taunton, J.5
Hegde, R.S.6
-
14
-
-
0037353039
-
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
-
DOI 10.1016/S1097-2765(03)00105-9
-
Harding HP, Zhang Y, Zeng H, et al. An integrated stress response regulates amino acid metabolism and resistance to oxidative stress. Mol Cell 2003;11:619-633 (Pubitemid 36385118)
-
(2003)
Molecular Cell
, vol.11
, Issue.3
, pp. 619-633
-
-
Harding, H.P.1
Zhang, Y.2
Zeng, H.3
Novoa, I.4
Lu, P.D.5
Calfon, M.6
Sadri, N.7
Yun, C.8
Popko, B.9
Paules, R.10
Stojdl, D.F.11
Bell, J.C.12
Hettmann, T.13
Leiden, J.M.14
Ron, D.15
-
15
-
-
0033118409
-
Complexes containing activating transcription factor (ATF)/cAMP- responsive-element-binding protein (CREB) interact with the CCAAT/enhancer- binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
-
DOI 10.1042/0264-6021:3390135
-
Fawcett TW, Martindale JL, Guyton KZ, et al. Complexes containing activating transcription factor (ATF)/cAMP responsive-element-binding protein (CREB) interact with the CCAAT/ enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem J 1999;339(Pt 1):135-141 (Pubitemid 29179300)
-
(1999)
Biochemical Journal
, vol.339
, Issue.1
, pp. 135-141
-
-
Fawcett, T.W.1
Martindale, J.L.2
Guyton, K.Z.3
Hai, T.4
Holbrook, N.J.5
-
16
-
-
34548189283
-
ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress
-
DOI 10.1016/j.devcel.2007.07.005, PII S1534580707002663
-
Wu J, Rutkowski DT, Dubois M, et al. ATF6α optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. Dev Cell 2007;13:351-364 (Pubitemid 47308675)
-
(2007)
Developmental Cell
, vol.13
, Issue.3
, pp. 351-364
-
-
Wu, J.1
Rutkowski, D.T.2
Dubois, M.3
Swathirajan, J.4
Saunders, T.5
Wang, J.6
Song, B.7
Yau, G.D.-Y.8
Kaufman, R.J.9
-
17
-
-
34548172495
-
Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1
-
DOI 10.1016/j.devcel.2007.07.018, PII S1534580707003000
-
Yamamoto K, Sato T, Matsui T, et al. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1. Dev Cell 2007;13:365-376 (Pubitemid 47308680)
-
(2007)
Developmental Cell
, vol.13
, Issue.3
, pp. 365-376
-
-
Yamamoto, K.1
Sato, T.2
Matsui, T.3
Sato, M.4
Okada, T.5
Yoshida, H.6
Harada, A.7
Mori, K.8
-
18
-
-
0032525990
-
A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
-
Tirasophon W, Welihinda AA, Kaufman RJ. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 1998;12:1812-1824 (Pubitemid 28304334)
-
(1998)
Genes and Development
, vol.12
, Issue.12
, pp. 1812-1824
-
-
Tirasophon, W.1
Welihinda, A.A.2
Kaufman, R.J.3
-
19
-
-
0032190546
-
Cloning of mammalian Ire1 reveals diversity in the ER stress responses
-
DOI 10.1093/emboj/17.19.5708
-
Wang XZ, Harding HP, Zhang Y, et al. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 1998;17:5708-5717 (Pubitemid 28445982)
-
(1998)
EMBO Journal
, vol.17
, Issue.19
, pp. 5708-5717
-
-
Wang, X.-Z.1
Harding, H.P.2
Zhang, Y.3
Jolicoeur, E.M.4
Kuroda, M.5
Ron, D.6
-
20
-
-
31944450850
-
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
-
DOI 10.1083/jcb.200507057
-
Oda Y, Okada T, Yoshida H, et al. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J Cell Biol 2006;172:383-393 (Pubitemid 43187935)
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.3
, pp. 383-393
-
-
Oda, Y.1
Okada, T.2
Yoshida, H.3
Kaufman, R.J.4
Nagata, K.5
Mori, K.6
-
21
-
-
23144451257
-
ERAD: The long road to destruction
-
DOI 10.1038/ncb0805-766
-
Meusser B, Hirsch C, Jarosch E, et al. ERAD: the long road to destruction. Nat Cell Biol 2005;7:766-772 (Pubitemid 41079045)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.8
, pp. 766-772
-
-
Meusser, B.1
Hirsch, C.2
Jarosch, E.3
Sommer, T.4
-
22
-
-
0036270698
-
Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
-
DOI 10.1038/nrm780
-
Tsai B, Ye Y, Rapoport TA. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol 2002;3:246-255 (Pubitemid 34619260)
-
(2002)
Nature Reviews Molecular Cell Biology
, vol.3
, Issue.4
, pp. 246-255
-
-
Tsai, B.1
Ye, Y.2
Rapoport, T.A.3
-
23
-
-
0035947773
-
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
-
DOI 10.1083/jcb.153.5.1061
-
Nishikawa SI, Fewell SW, Kato Y, et al. Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation. J Cell Biol 2001;153:1061-1070 (Pubitemid 34289244)
-
(2001)
Journal of Cell Biology
, vol.153
, Issue.5
, pp. 1061-1069
-
-
Nishikawa, S.-I.1
Fewell, S.W.2
Kato, Y.3
Brodsky, J.L.4
Endo, T.5
-
24
-
-
0033611127
-
Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase
-
DOI 10.1083/jcb.147.7.1443
-
Gillece P, Luz JM, Lennarz WJ, et al. Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase. J Cell Biol 1999;147:1443-1456 (Pubitemid 30027400)
-
(1999)
Journal of Cell Biology
, vol.147
, Issue.7
, pp. 1443-1456
-
-
Gillece, P.1
Luz, J.M.2
Lennarz, W.J.3
De La Cruz, F.J.4
Romisch, K.5
-
25
-
-
0034981027
-
A novel ER α-mannosidase-like protein accelerates ER-associated degradation
-
Hosokawa N, Wada I, Hasegawa K, et al. A novel ER α-mannosidase- like protein accelerates ER-associated degradation. EMBO reports 2001;2:415-422 (Pubitemid 32509958)
-
(2001)
EMBO Reports
, vol.2
, Issue.5
, pp. 415-422
-
-
Hosokawa, N.1
Wada, I.2
Hasegawa, K.3
Yorihuzi, T.4
Tremblay, L.O.5
Herscovics, A.6
Nagata, K.7
-
26
-
-
48249117110
-
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER
-
Ushioda R, Hoseki J, Araki K, et al. ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science 2008;321:569-572
-
(2008)
Science
, vol.321
, pp. 569-572
-
-
Ushioda, R.1
Hoseki, J.2
Araki, K.3
-
27
-
-
0035818999
-
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
-
DOI 10.1038/414652a
-
Ye Y, Meyer HH, Rapoport TA. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 2001;414:652-656 (Pubitemid 33151262)
-
(2001)
Nature
, vol.414
, Issue.6864
, pp. 652-656
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
28
-
-
34249069585
-
Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian in Vitro System
-
DOI 10.1016/j.cell.2007.03.046, PII S0092867407005156
-
Wahlman J, DeMartino GN, Skach WR, et al. Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system. Cell 2007;129:943-955 (Pubitemid 46802700)
-
(2007)
Cell
, vol.129
, Issue.5
, pp. 943-955
-
-
Wahlman, J.1
Demartino, G.N.2
Skach, W.R.3
Bulleid, N.J.4
Brodsky, J.L.5
Johnson, A.6
-
29
-
-
0032728066
-
Posttranslational protein translocation across the membrane of the endoplasmic reticulum
-
DOI 10.1515/BC.1999.145
-
Rapoport TA, Matlack KE, Plath K, et al. Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biol Chem 1999;380:1143-1150 (Pubitemid 29516402)
-
(1999)
Biological Chemistry
, vol.380
, Issue.10
, pp. 1143-1150
-
-
Rapoport, T.A.1
Matlack, K.E.S.2
Plath, K.3
Misselwitz, B.4
Staeck, O.5
-
30
-
-
4143107016
-
Structural insight into the protein translocation channel
-
DOI 10.1016/j.sbi.2004.07.006, PII S0959440X04001137
-
Clemons WM Jr, Menetret JF, Akey CW, et al. Structural insight into the protein translocation channel. Curr Opin Struct Biol 2004;14:390-396 (Pubitemid 39094345)
-
(2004)
Current Opinion in Structural Biology
, vol.14
, Issue.4
, pp. 390-396
-
-
Clemons Jr., W.M.1
Menetret, J.-F.2
Akey, C.W.3
Rapoport, T.A.4
-
31
-
-
0033382189
-
The engagement of Sec61p in the ER dislocation process
-
Zhou M, Schekman R. The engagement of Sec61p in the ER dislocation process. Mol Cell 1999;4:925-934 (Pubitemid 30054899)
-
(1999)
Molecular Cell
, vol.4
, Issue.6
, pp. 925-934
-
-
Zhou, M.1
Schekman, R.2
-
32
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
DOI 10.1038/nature02656
-
Ye Y, Shibata Y, Yun C, et al. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 2004;429:841-847 (Pubitemid 38843292)
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
33
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
DOI 10.1038/nature02592
-
Lilley BN, Ploegh HL. A membrane protein required for dislocation of misfolded proteins from the ER. Nature 2004;429:834-840 (Pubitemid 38843291)
-
(2004)
Nature
, vol.429
, Issue.6994
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
34
-
-
26244431960
-
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
-
DOI 10.1073/pnas.0505014102
-
Lilley BN, Ploegh HL. Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc Natl Acad Sci USA 2005;102:14296-14301 (Pubitemid 41429692)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.40
, pp. 14296-14301
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
35
-
-
26444621357
-
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane
-
DOI 10.1073/pnas.0505006102
-
Ye Y, Shibata Y, Kikkert M, et al. Inaugural article: recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Proc Natl Acad Sci USA 2005;102:14132-14138 (Pubitemid 41429665)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.40
, pp. 14132-14138
-
-
Ye, Y.1
Shibata, Y.2
Kikkert, M.3
Van Voorden, S.4
Wiertz, E.5
Rapoport, T.A.6
-
36
-
-
4444253303
-
Survival and apoptosis signals in ER stress: The role of protein kinases
-
DOI 10.1016/j.jchemneu.2004.05.004, PII S0891061804000547
-
Kadowaki H, Nishitoh H, Ichijo H. Survival and apoptosis signals in ER stress: the role of protein kinases. J Chem Neuroanat 2004;28:93-100 (Pubitemid 39195254)
-
(2004)
Journal of Chemical Neuroanatomy
, vol.28
, Issue.1-2
, pp. 93-100
-
-
Kadowaki, H.1
Nishitoh, H.2
Ichijo, H.3
-
37
-
-
1842843855
-
Roles of CHOP/GADD153 in endoplasmic reticulum stress
-
DOI 10.1038/sj.cdd.4401373
-
Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004;11:381-389 (Pubitemid 38489416)
-
(2004)
Cell Death and Differentiation
, vol.11
, Issue.4
, pp. 381-389
-
-
Oyadomari, S.1
Mori, M.2
-
38
-
-
31044452359
-
Generating disulfides enzymatically: Reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p
-
DOI 10.1073/pnas.0506448103
-
Gross E, Sevier CS, Heldman N, et al. Generating disulfides enzymatically: reaction products and electron acceptors of the endoplasmic reticulum thiol oxidase Ero1p. Proc Natl Acad Sci USA 2006;103:299-304 (Pubitemid 43122395)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.2
, pp. 299-304
-
-
Gross, E.1
Sevier, C.S.2
Heldman, N.3
Vitu, E.4
Bentzur, M.5
Kaiser, C.A.6
Thorpe, C.7
Fass, D.8
-
39
-
-
0027362667
-
Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
-
Krajewski S, Tanaka S, Takayama S, et al. Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 1993;53:4701-4714 (Pubitemid 23304404)
-
(1993)
Cancer Research
, vol.53
, Issue.18
, pp. 4701-4714
-
-
Krajewski, S.1
Tanaka, S.2
Takayama, S.3
Schibler, M.J.4
Fenton, W.5
Reed, J.C.6
-
40
-
-
1442359853
-
There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum
-
DOI 10.1016/j.bbamcr.2003.07.001, PII S0167488903001782
-
Annis MG, Yethon JA, Leber B, et al. There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum. Biochim Biophys Acta 2004;1644:115-123 (Pubitemid 38281268)
-
(2004)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1644
, Issue.2-3
, pp. 115-123
-
-
Annis, M.G.1
Yethon, J.A.2
Leber, B.3
Andrews, D.W.4
-
41
-
-
0344897663
-
Bcl-2 on the endoplasmic reticulum: Protecting the mitochondria from a distance
-
DOI 10.1242/jcs.00829
-
Thomenius MJ, Distelhorst CW. Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance. J Cell Sci 2003;116:4493-4499 (Pubitemid 37461604)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.22
, pp. 4493-4499
-
-
Thomenius, M.J.1
Distelhorst, C.W.2
-
42
-
-
54949135707
-
The endoplasmic reticulum in apoptosis and autophagy: Role of the BCL-2 protein family
-
Heath-Engel HM, Chang NC, Shore GC. The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family. Oncogene 2008;27:6419-6433
-
(2008)
Oncogene
, vol.27
, pp. 6419-6433
-
-
Heath-Engel, H.M.1
Chang, N.C.2
Shore, G.C.3
-
43
-
-
0035876483
-
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
-
DOI 10.1101/gad.897601
-
Zong WX, Lindsten T, Ross AJ, et al. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001;15:1481-1486 (Pubitemid 32552527)
-
(2001)
Genes and Development
, vol.15
, Issue.12
, pp. 1481-1486
-
-
Zong, W.-X.1
Lindsten, T.2
Ross, A.J.3
MacGregor, G.R.4
Thompson, C.B.5
-
44
-
-
0035957653
-
Proapoptotic BAX and BAK: A requisite gateway to mitochondrial dysfunction and death
-
DOI 10.1126/science.1059108
-
Wei MC, Zong WX, Cheng EH, et al. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death. Science 2001;292:727-730 (Pubitemid 32385543)
-
(2001)
Science
, vol.292
, Issue.5517
, pp. 727-730
-
-
Wei, M.C.1
Zong, W.-X.2
Cheng, E.H.-Y.3
Lindsten, T.4
Panoutsakopoulou, V.5
Ross, A.J.6
Roth, K.A.7
Macgregor, G.R.8
Thompson, C.B.9
Korsmeyer, S.J.10
-
45
-
-
0034698878
-
Cross-talk between two cysteine protease families: Activation of caspase-12 by calpain in apoptosis
-
DOI 10.1083/jcb.150.4.887
-
Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 2000;150:887-894 (Pubitemid 30663424)
-
(2000)
Journal of Cell Biology
, vol.150
, Issue.4
, pp. 887-894
-
-
Nakagawa, T.1
Yuan, J.2
-
46
-
-
0032080004
-
Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver
-
DOI 10.1074/jbc.273.18.10815
-
Chandler JM, Cohen GM, MacFarlane M. Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J Biol Chem 1998;273:10815-10818 (Pubitemid 28204912)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.18
, pp. 10815-10818
-
-
Chandler, J.M.1
Cohen, G.M.2
MacFarlane, M.3
-
47
-
-
19944426148
-
Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation
-
DOI 10.1038/sj.cdd.4401528
-
Kadowaki H, Nishitoh H, Urano F, et al. Amyloid β induces neuronal cell death through ROS-mediated ASK1 activation. Cell Death Differ 2005;12:19-24 (Pubitemid 40090025)
-
(2005)
Cell Death and Differentiation
, vol.12
, Issue.1
, pp. 19-24
-
-
Kadowaki, H.1
Nishitoh, H.2
Urano, F.3
Sadamitsu, C.4
Matsuzawa, A.5
Takeda, K.6
Masutani, H.7
Yodoi, J.8
Urano, Y.9
Nagano, T.10
Ichijo, H.11
-
48
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
-
DOI 10.1038/47513
-
Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000;403:98-103 (Pubitemid 30038529)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
49
-
-
2442432416
-
Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death
-
DOI 10.1083/jcb.200310015
-
Hitomi J, Katayama T, Eguchi Y, et al. Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Aβ-induced cell death. J Cell Biol 2004;165:347-356 (Pubitemid 38649910)
-
(2004)
Journal of Cell Biology
, vol.165
, Issue.3
, pp. 347-356
-
-
Hitomi, J.1
Katayama, T.2
Eguchi, Y.3
Kudo, T.4
Taniguchi, M.5
Koyama, Y.6
Manabe, T.7
Yamagishi, S.8
Bando, Y.9
Imaizumi, K.10
Tsujimoto, Y.11
Tohyama, M.12
-
50
-
-
0032158987
-
ASK1 is essential for JNK/SAPK activation by TRAF2
-
Nishitoh H, Saitoh M, Mochida Y, et al. ASK1 is essential for JNK/SAPK activation by TRAF2. Mol Cell 1998;2:389-395 (Pubitemid 128379279)
-
(1998)
Molecular Cell
, vol.2
, Issue.3
, pp. 389-395
-
-
Nishitoh, H.1
Saitoh, M.2
Mochida, Y.3
Takeda, K.4
Nakano, H.5
Rothe, M.6
Miyazono, K.7
Ichijo, H.8
-
51
-
-
43149114461
-
Requirement of reactive oxygen species dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage
-
Noguchi T, Ishii K, Fukutomi H, et al. Requirement of reactive oxygen species dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J Biol Chem 2008;283:7657-7665
-
(2008)
J Biol Chem
, vol.283
, pp. 7657-7665
-
-
Noguchi, T.1
Ishii, K.2
Fukutomi, H.3
-
52
-
-
1642487129
-
2+ - Induced p38 MAP kinase activation
-
DOI 10.1038/sj.embor.7400072
-
Takeda K, Matsuzawa A, Nishitoh H, et al. Involvement of ASK1 in Ca2+ -induced p38 MAP kinase activation. EMBO Rep 2004;5:161-166 (Pubitemid 38401195)
-
(2004)
EMBO Reports
, vol.5
, Issue.2
, pp. 161-166
-
-
Takeda, K.1
Matsuzawa, A.2
Nishitoh, H.3
Tobiume, K.4
Kishida, S.5
Ninomiya-Tsuji, J.6
Matsumoto, K.7
Ichijo, H.8
-
53
-
-
0032544309
-
Activation of Apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
-
DOI 10.1126/science.281.5384.1860
-
Chang HY, Nishitoh H, Yang X, et al. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 1998;281:1860-1863 (Pubitemid 28450508)
-
(1998)
Science
, vol.281
, Issue.5384
, pp. 1860-1863
-
-
Chang, H.Y.1
Nishitoh, H.2
Yang, X.3
Ichijo, H.4
Baltimore, D.5
-
54
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal regulating kinase (ASK) 1. EMBO J 1998;17:2596-2606
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
-
55
-
-
0033986791
-
Role of apoptosis signal-regulating kinase in regulation of the c-Jun N- Terminal kinase pathway and apoptosis in sympathetic neurons
-
Kanamoto T, Mota M, Takeda K, et al. Role of apoptosis signal-regulating kinase in regulation of the c-Jun N-terminal kinase pathway and apoptosis in sympathetic neurons. Mol Cell Biol 2000;20:196-204 (Pubitemid 30002561)
-
(2000)
Molecular and Cellular Biology
, vol.20
, Issue.1
, pp. 196-204
-
-
Kanamoto, T.1
Mota, M.2
Takeda, K.3
Rubin, L.L.4
Miyazono, K.5
Ichijo, H.6
Bazenet, C.E.7
-
56
-
-
0034714355
-
Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria-dependent caspase activation
-
DOI 10.1074/jbc.M003412200
-
Hatai T, Matsuzawa A, Inoshita S, et al. Execution of apoptosis signal-regulating kinase 1 (ASK1)-induced apoptosis by the mitochondria- dependent caspase activation. J Biol Chem 2000;275:26576-26581 (Pubitemid 30676717)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.34
, pp. 26576-26581
-
-
Hatai, T.1
Matsuzawa, A.2
Inoshita, S.3
Mochida, Y.4
Kuroda, T.5
Sakamaki, K.6
Kuida, K.7
Yonehara, S.8
Ichijo, H.9
Takeda, K.10
-
57
-
-
0037115761
-
Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): A distinct pathway from those of chemically induced and receptor-mediated apoptosis
-
DOI 10.1042/BJ20020101
-
Saeki K, Kobayashi N, Inazawa Y, et al. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor mediated apoptosis. Biochem J 2002;368:705-720 (Pubitemid 36042672)
-
(2002)
Biochemical Journal
, vol.368
, Issue.3
, pp. 705-720
-
-
Saeki, K.1
Kobayashi, N.2
Inazawa, Y.3
Zhang, H.4
Nishitoh, H.5
Ichijo, H.6
Saeki, K.7
Isemura, M.8
Yuo, A.9
-
58
-
-
36849043546
-
Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
-
DOI 10.1128/MCB.00227-07
-
Fujino G, Noguchi T, Matsuzawa A, et al. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol 2007;27:8152-8163 (Pubitemid 350234230)
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.23
, pp. 8152-8163
-
-
Fujino, G.1
Noguchi, T.2
Matsuzawa, A.3
Yamauchi, S.4
Saitoh, M.5
Takeda, K.6
Ichijo, H.7
-
59
-
-
27744559915
-
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death
-
DOI 10.1074/jbc.M506771200
-
Noguchi T, Takeda K, Matsuzawa A, et al. Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death. J Biol Chem 2005;280:37033-37040 (Pubitemid 41587787)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.44
, pp. 37033-37040
-
-
Noguchi, T.1
Takeda, K.2
Matsuzawa, A.3
Saegusa, K.4
Nakano, H.5
Gohda, J.6
Inoue, J.-I.7
Ichijo, H.8
-
60
-
-
0034723235
-
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
-
DOI 10.1126/science.287.5453.664
-
Urano F, Wang X, Bertolotti A, et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000;287:664-666 • This paper demonstrates that IRE1 mediates ER stress-induced JNK activation. (Pubitemid 30070916)
-
(2000)
Science
, vol.287
, Issue.5453
, pp. 664-666
-
-
Urano, F.1
Wang, X.2
Bertolotti, A.3
Zhang, Y.4
Chung, P.5
Harding, H.P.6
Ron, D.7
-
61
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
DOI 10.1016/S0896-6273(03)00355-6
-
Putcha GV, Le S, Frank S, et al. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 2003;38:899-914 (Pubitemid 36782382)
-
(2003)
Neuron
, vol.38
, Issue.6
, pp. 899-914
-
-
Putcha, G.V.1
Le, S.2
Frank, S.3
Besirli, C.G.4
Clark, K.5
Chu, B.6
Alix, S.7
Youle, R.J.8
Lamarche, A.9
Maroney, A.C.10
Johnson Jr., E.M.11
-
63
-
-
0037113878
-
Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress
-
DOI 10.1074/jbc.M207951200
-
Inoshita S, Takeda K, Hatai T, et al. Phosphorylation and inactivation of myeloid cell leukemia 1 by JNK in response to oxidative stress. J Biol Chem 2002;277:43730-43734 (Pubitemid 36157790)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 43730-43734
-
-
Inoshita, S.1
Takeda, K.2
Hatai, T.3
Terada, Y.4
Sano, M.5
Hata, J.6
Umezawa, A.7
Ichijo, H.8
-
64
-
-
0029938805
-
Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase
-
Wang XZ, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 1996;272:1347-1349 (Pubitemid 26199977)
-
(1996)
Science
, vol.272
, Issue.5266
, pp. 1347-1349
-
-
Wang, X.1
Ron, D.2
-
65
-
-
0035936804
-
Amyotrophic lateral sclerosis: Unfolding the toxicity of the misfolded
-
DOI 10.1016/S0092-8674(01)00244-6
-
Julien JP. Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded. Cell 2001;104:581-591 (Pubitemid 32201952)
-
(2001)
Cell
, vol.104
, Issue.4
, pp. 581-591
-
-
Julien, J.-P.1
-
66
-
-
33749563294
-
Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein-disulfide isomerase with superoxide dismutase 1
-
DOI 10.1074/jbc.M603393200
-
Atkin JD, Farg MA, Turner BJ, et al. Induction of the unfolded protein response in familial amyotrophic lateral sclerosis and association of protein disulfide isomerase with superoxide dismutase 1. J Biol Chem 2006;281:30152-30165 (Pubitemid 44537023)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 30152-30165
-
-
Atkin, J.D.1
Farg, M.A.2
Turner, B.J.3
Tomas, D.4
Lysaght, J.A.5
Nunan, J.6
Rembach, A.7
Nagley, P.8
Beart, P.M.9
Cheema, S.S.10
Horne, M.K.11
-
67
-
-
33645798615
-
Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model
-
Kikuchi H, Almer G, Yamashita S, et al. Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proc Natl Acad Sci USA 2006;103:6025-6030
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 6025-6030
-
-
Kikuchi, H.1
Almer, G.2
Yamashita, S.3
-
68
-
-
0346034856
-
Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice
-
DOI 10.1016/S0006-291X(03)00353-X
-
Tobisawa S, Hozumi Y, Arawaka S, et al. Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice. Biochem Biophys Res Commun 2003;303:496-503 (Pubitemid 36349197)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.303
, Issue.2
, pp. 496-503
-
-
Tobisawa, S.1
Hozumi, Y.2
Arawaka, S.3
Koyama, S.4
Wada, M.5
Nagai, M.6
Aoki, M.7
Itoyama, Y.8
Goto, K.9
Kato, T.10
-
69
-
-
0037068836
-
Motoneuron death triggered by a specific pathway downstream of fas: Potentiation by ALS-linked SOD1 mutations
-
DOI 10.1016/S0896-6273(02)00905-4
-
Raoul C, Estevez AG, Nishimune H, et al. Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron 2002;35:1067-1083 (Pubitemid 35279535)
-
(2002)
Neuron
, vol.35
, Issue.6
, pp. 1067-1083
-
-
Raoul, C.1
Estevez, A.G.2
Nishimune, H.3
Cleveland, D.W.4
Delapeyriere, O.5
Henderson, C.E.6
Haase, G.7
Pettmann, B.8
-
70
-
-
19444374567
-
Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice
-
Holasek SS, Wengenack TM, Kandimalla KK, et al. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. Brain Res 2005;1045:185-198
-
(2005)
Brain Res
, vol.1045
, pp. 185-198
-
-
Holasek, S.S.1
Wengenack, T.M.2
Kandimalla, K.K.3
-
71
-
-
32244441514
-
Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS
-
DOI 10.1016/j.mcn.2005.09.009, PII S1044743105002265
-
Veglianese P, Lo Coco D, Bao Cutrona M, et al. Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Mol Cell Neurosci 2006;31:218-231 (Pubitemid 43214532)
-
(2006)
Molecular and Cellular Neuroscience
, vol.31
, Issue.2
, pp. 218-231
-
-
Veglianese, P.1
Lo Coco, D.2
Bao Cutrona, M.3
Magnoni, R.4
Pennacchini, D.5
Pozzi, B.6
Gowing, G.7
Julien, J.P.8
Tortarolo, M.9
Bendotti, C.10
-
72
-
-
5644242311
-
Activation of programmed cell death markers in ventral horn motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in a transgenic mouse model
-
DOI 10.1016/j.brainres.2004.08.054, PII S0006899304013605
-
Wengenack TM, Holasek SS, Montano CM, et al. Activation of programmed cell death markers in ventral horn motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in a transgenic mouse model. Brain Res 2004;1027:73-86 (Pubitemid 39370997)
-
(2004)
Brain Research
, vol.1027
, Issue.1-2
, pp. 73-86
-
-
Wengenack, T.M.1
Holasek, S.S.2
Montano, C.M.3
Gregor, D.4
Curran, G.L.5
Poduslo, J.F.6
-
73
-
-
0031761706
-
Protein precipitation: A common etiology in neurodegenerative disorders?
-
Kakizuka A. Protein precipitation: a common etiology in neurodegenerative disorders? Trends Genet 1998;14:396-402
-
(1998)
Trends Genet
, vol.14
, pp. 396-402
-
-
Kakizuka, A.1
-
75
-
-
0036122933
-
Identification of ter94, Drosophila VCP, as a modulator of polyglutamine-induced neurodegeneration
-
DOI 10.1038/sj.cdd.4400955
-
Higashiyama H, Hirose F, Yamaguchi M, et al. Identification of ter94, Drosophila VCP, as a modulator of polyglutamine induced neurodegeneration. Cell Death Differ 2002;9:264-273 (Pubitemid 34223870)
-
(2002)
Cell Death and Differentiation
, vol.9
, Issue.3
, pp. 264-273
-
-
Higashiyama, H.1
Hirose, F.2
Yamaguchi, M.3
Inoue, Y.H.4
Fujikake, N.5
Matsukage, A.6
Kakizuka, A.7
-
76
-
-
0034772572
-
VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration
-
DOI 10.1038/sj.cdd.4400907
-
Hirabayashi M, Inoue K, Tanaka K, et al. VCP/p97 in abnormal protein aggregates, cytoplasmic vacuoles, and cell death, phenotypes relevant to neurodegeneration. Cell Death Differ 2001;8:977-984 (Pubitemid 32994648)
-
(2001)
Cell Death and Differentiation
, vol.8
, Issue.10
, pp. 977-984
-
-
Hirabayashi, M.1
Inoue, K.2
Tanaka, K.3
Nakadate, K.4
Ohsawa, Y.5
Kamei, Y.6
Popiel, A.H.7
Sinohara, A.8
Iwamatsu, A.9
Kimura, Y.10
Uchiyama, Y.11
Hori, S.12
Kakizuka, A.13
-
77
-
-
57749116408
-
Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
-
Duennwald ML, Lindquist S. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 2008;22:3308-3319
-
(2008)
Genes Dev
, vol.22
, pp. 3308-3319
-
-
Duennwald, M.L.1
Lindquist, S.2
-
78
-
-
42449161835
-
ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease
-
Arning L, Monte D, Hansen W, et al. ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease. J Mol Med 2008;86:485-490
-
(2008)
J Mol Med
, vol.86
, pp. 485-490
-
-
Arning, L.1
Monte, D.2
Hansen, W.3
-
79
-
-
0033258544
-
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response
-
Katayama T, Imaizumi K, Sato N, et al. Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response. Nat Cell Biol 1999;1:479-485 (Pubitemid 129503667)
-
(1999)
Nature Cell Biology
, vol.1
, Issue.8
, pp. 479-485
-
-
Katayama, T.1
Imaizumi, K.2
Sato, N.3
Miyoshi, K.4
Kudo, T.5
Hitomi, J.6
Morihara, T.7
Yoneda, T.8
Gomi, F.9
Mori, Y.10
Nakano, Y.11
Takeda, J.12
Tsuda, T.13
Itoyama, Y.14
Murayama, O.15
Takashima, A.16
St George-Hyslop, P.17
Takeda, M.18
Tohyama, M.19
-
80
-
-
0035900779
-
Disturbed Activation of Endoplasmic Reticulum Stress Transducers by Familial Alzheimer's Disease-linked Presenilin-1 Mutations
-
DOI 10.1074/jbc.M104096200
-
Katayama T, Imaizumi K, Honda A, et al. Disturbed activation of endoplasmic reticulum stress transducers by familial Alzheimer's disease-linked presenilin-1 mutations. J Biol Chem 2001;276:43446-43454 (Pubitemid 37371036)
-
(2001)
Journal of Biological Chemistry
, vol.276
, Issue.46
, pp. 43446-43454
-
-
Katayama, T.1
Imaizumi, K.2
Honda, A.3
Yoneda, T.4
Kudo, T.5
Takeda, M.6
Mori, K.7
Rozmahel, R.8
Fraser, P.9
St George-Hyslop, P.10
Tohyama, M.11
-
81
-
-
1842562209
-
An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease
-
DOI 10.1038/sj.emboj.7600049
-
Onuki R, Bando Y, Suyama E, et al. An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease. EMBO J 2004;23:959-968 (Pubitemid 38418762)
-
(2004)
EMBO Journal
, vol.23
, Issue.4
, pp. 959-968
-
-
Onuki, R.1
Bando, Y.2
Suyama, E.3
Katayama, T.4
Kawasaki, H.5
Baba, T.6
Tohyama, M.7
Taira, K.8
-
82
-
-
33646376968
-
A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease
-
Saltini G, Dominici R, Lovati C, et al. A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease. Neurosci Lett 2006;398:53-58
-
(2006)
Neurosci Lett
, vol.398
, pp. 53-58
-
-
Saltini, G.1
Dominici, R.2
Lovati, C.3
-
83
-
-
0028233494
-
Hydrogen peroxide mediates amyloid β protein toxicity
-
DOI 10.1016/0092-8674(94)90131-7
-
Behl C, Davis JB, Lesley R, et al. Hydrogen peroxide mediates amyloid β protein toxicity. Cell 1994;77:817-827 (Pubitemid 24187680)
-
(1994)
Cell
, vol.77
, Issue.6
, pp. 817-827
-
-
Behl, C.1
Davis, J.B.2
Lesley, R.3
Schubert, D.4
-
84
-
-
0028180518
-
A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: Relevance to Alzheimer disease
-
Hensley K, Carney JM, Mattson MP, et al. A model for β-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease. Proc Natl Acad Sci USA 1994;91:3270-3274 (Pubitemid 24130218)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.8
, pp. 3270-3274
-
-
Hensley, K.1
Carney, J.M.2
Mattson, M.P.3
Aksenova, M.4
Harris, M.5
Wu, J.F.6
Floyd, R.A.7
Butterfield, D.A.8
-
85
-
-
0028118846
-
Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death
-
Shearman MS, Ragan CI, Iversen LL. Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of β-amyloid-mediated cell death. Proc Natl Acad Sci USA 1994;91:1470-1474 (Pubitemid 24059034)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.4
, pp. 1470-1474
-
-
Shearman, M.S.1
Ragan, C.I.2
Iversen, L.L.3
-
86
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
DOI 10.1038/33416
-
Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-608 (Pubitemid 28207717)
-
(1998)
Nature
, vol.392
, Issue.6676
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
87
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
DOI 10.1038/77060
-
Shimura H, Hattori N, Kubo S, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat Genet 2000;25:302-305 (Pubitemid 30437317)
-
(2000)
Nature Genetics
, vol.25
, Issue.3
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.-I.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
89
-
-
0034680913
-
Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
-
DOI 10.1074/jbc.C000447200
-
Imai Y, Soda M, Takahashi R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 2000;275:35661-35664 (Pubitemid 30841094)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.46
, pp. 35661-35664
-
-
Imai, Y.1
Soda, M.2
Takahashi, R.3
-
90
-
-
0036345454
-
CHIP is associated with Parkin, a gene responsible for familial Parkinson's Disease, and enhances its ubiquitin ligase activity
-
DOI 10.1016/S1097-2765(02)00583-X
-
Imai Y, Soda M, Hatakeyama S, et al. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 2002;10:55-67 (Pubitemid 34876562)
-
(2002)
Molecular Cell
, vol.10
, Issue.1
, pp. 55-67
-
-
Imai, Y.1
Soda, M.2
Hatakeyama, S.3
Akagi, T.4
Hashikawa, T.5
Nakayama, K.-I.6
Takahashi, R.7
-
91
-
-
0035967883
-
An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
-
DOI 10.1016/S0092-8674(01)00407-X
-
Imai Y, Soda M, Inoue H, et al. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 2001;105:891-902 (Pubitemid 32635090)
-
(2001)
Cell
, vol.105
, Issue.7
, pp. 891-902
-
-
Imai, Y.1
Soda, M.2
Inoue, H.3
Hattori, N.4
Mizuno, Y.5
Takahashi, R.6
-
92
-
-
22544458436
-
Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila
-
DOI 10.1073/pnas.0500346102
-
Cha GH, Kim S, Park J, et al. Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila. Proc Natl Acad Sci USA 2005;102:10345-10350 (Pubitemid 41023373)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.29
, pp. 10345-10350
-
-
Cha, G.-H.1
Kim, S.2
Park, J.3
Lee, E.4
Kim, M.5
Lee, S.B.6
Kim, J.M.7
Chung, J.8
Cho, K.S.9
-
93
-
-
0028127058
-
Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
-
DOI 10.1016/0306-4522(94)90566-5
-
Walkinshaw G, Waters CM. Neurotoxin induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neuroscience 1994;63:975-987 (Pubitemid 24366149)
-
(1994)
Neuroscience
, vol.63
, Issue.4
, pp. 975-987
-
-
Walkinshaw, G.1
Waters, C.M.2
-
94
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
DOI 10.1038/81834
-
Betarbet R, Sherer TB, MacKenzie G, et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat Neurosci 2000;3:1301-1306 (Pubitemid 30951645)
-
(2000)
Nature Neuroscience
, vol.3
, Issue.12
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
95
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu EJ, Harding HP, Angelastro JM, et al. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci 2002;22:10690-10698 (Pubitemid 36005143)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.24
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
Vitolo, O.V.4
Ron, D.5
Greene, L.A.6
-
96
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
DOI 10.1126/science.1077209
-
Bonifati V, Rizzu P, van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset Parkinsonism. Science 2003;299:256-259 (Pubitemid 36131051)
-
(2003)
Science
, vol.299
, Issue.5604
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
Van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.J.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
Van Dongen, J.W.11
Vanacore, N.12
Van Swieten, J.C.13
Brice, A.14
Meco, G.15
Van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
97
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
DOI 10.1038/sj.embor.7400074
-
Taira T, Saito Y, Niki T, et al. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Rep 2004;5:213-218 (Pubitemid 38401204)
-
(2004)
EMBO Reports
, vol.5
, Issue.2
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.M.4
Takahashi, K.5
Ariga, H.6
-
98
-
-
22144465488
-
Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death
-
DOI 10.1073/pnas.0409635102
-
Junn E, Taniguchi H, Jeong BS, et al. Interaction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell death. Proc Natl Acad Sci USA 2005;102:9691-9696 (Pubitemid 40981742)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.27
, pp. 9691-9696
-
-
Junn, E.1
Taniguchi, H.2
Jeong, B.S.3
Zhao, X.4
Ichijo, H.5
Mouradian, M.M.6
-
99
-
-
59449108481
-
Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1
-
Kim I, Shu CW, Xu W, et al. Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. J Biol Chem 2009;284:1593-1603
-
(2009)
J Biol Chem
, vol.284
, pp. 1593-1603
-
-
Kim, I.1
Shu, C.W.2
Xu, W.3
-
100
-
-
0035065836
-
ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis
-
DOI 10.1093/embo-reports/kve046
-
Tobiume K, Matsuzawa A, Takahashi T, et al. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep 2001;2:222-228 (Pubitemid 32273301)
-
(2001)
EMBO Reports
, vol.2
, Issue.3
, pp. 222-228
-
-
Tobiume, K.1
Matsuzawa, A.2
Takahashi, T.3
Nishitoh, H.4
Morita, K.-I.5
Takeda, K.6
Minowa, O.7
Miyazono, K.8
Noda, T.9
Ichijo, H.10
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