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Volumn 13, Issue 6, 2009, Pages 653-664

Targeting ASK1 in ER stress-related neurodegenerative diseases

Author keywords

Apoptosis; ASK1; ER stress; Neurodegenerative diseases

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; AMYLOID BETA PROTEIN; APOPTOSIS SIGNAL REGULATING KINASE 1; CASPASE; PARKIN; POLYGLUTAMINE; REACTIVE OXYGEN METABOLITE; X BOX BINDING PROTEIN 1;

EID: 67649586652     PISSN: 14728222     EISSN: None     Source Type: Journal    
DOI: 10.1517/14728220902980249     Document Type: Review
Times cited : (42)

References (100)
  • 1
    • 33749492425 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress signaling in disease
    • DOI 10.1152/physrev.00015.2006
    • Marciniak SJ, Ron D. Endoplasmic reticulum stress signaling in disease. Physiol Rev 2006;86:1133-1149 (Pubitemid 44521649)
    • (2006) Physiological Reviews , vol.86 , Issue.4 , pp. 1133-1149
    • Marciniak, S.J.1    Ron, D.2
  • 2
    • 57049117856 scopus 로고    scopus 로고
    • Cell death and endoplasmic reticulum stress: Disease relevance and therapeutic opportunities
    • Kim I, Xu W, Reed JC. Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities. Nat Rev Drug Discov 2008;7:1013-1030
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 1013-1030
    • Kim, I.1    Xu, W.2    Reed, J.C.3
  • 3
    • 36248949141 scopus 로고    scopus 로고
    • The endoplasmic reticulum and the unfolded protein response
    • DOI 10.1016/j.semcdb.2007.09.003, PII S1084952107001498, Degredation of Misfolded Glycoproteins
    • Malhotra JD, Kaufman RJ. The endoplasmic reticulum and the unfolded protein response. Semin Cell Dev Biol 2007;18:716-731 (Pubitemid 350138453)
    • (2007) Seminars in Cell and Developmental Biology , vol.18 , Issue.6 , pp. 716-731
    • Malhotra, J.D.1    Kaufman, R.J.2
  • 4
    • 0035066383 scopus 로고    scopus 로고
    • Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
    • Kyriakis JM, Avruch J. Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001;81:807-869 (Pubitemid 32267078)
    • (2001) Physiological Reviews , vol.81 , Issue.2 , pp. 807-869
    • Kyriakis, J.M.1    Avruch, J.2
  • 5
    • 0032928614 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase: Conservation of a three-kinase module from yeast to human
    • Widmann C, Gibson S, Jarpe MB, et al. Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human. Physiol Rev 1999;79:143-180 (Pubitemid 29056951)
    • (1999) Physiological Reviews , vol.79 , Issue.1 , pp. 143-180
    • Widmann, C.1    Gibson, S.2    Jarpe, M.B.3    Johnson, G.L.4
  • 8
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • DOI 10.1101/gad.992302
    • Nishitoh H, Matsuzawa A, Tobiume K, et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 2002;16:1345-1355 • The first paper, to our knowledge, about the important role of ASK1 in ER stress-induced cell death. (Pubitemid 34615088)
    • (2002) Genes and Development , vol.16 , Issue.11 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3    Saegusa, K.4    Takeda, K.5    Inoue, K.6    Hori, S.7    Kakizuka, A.8    Ichijo, H.9
  • 9
    • 0033782015 scopus 로고    scopus 로고
    • Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
    • DOI 10.1038/35014014
    • Bertolotti A, Zhang Y, Hendershot LM, et al. Dynamic interaction of BiP and ER stress transducers in the unfolded- protein response. Nat Cell Biol 2000;2:326-332 (Pubitemid 30781088)
    • (2000) Nature Cell Biology , vol.2 , Issue.6 , pp. 326-332
    • Bertolotti, A.1    Zhang, Y.2    Hendershot, L.M.3    Harding, H.P.4    Ron, D.5
  • 11
    • 33644858343 scopus 로고    scopus 로고
    • The unfolded protein response: A stress signaling pathway critical for health and disease
    • PII 0000611420060124100018
    • Zhang K, Kaufman RJ. The unfolded protein response: a stress signaling pathway critical for health and disease. Neurology 2006;66:S102-9 (Pubitemid 43739994)
    • (2006) Neurology , vol.66 , Issue.2 SUPPL. 1
    • Zhang, K.1    Kaufman, R.J.2
  • 12
    • 33745893809 scopus 로고    scopus 로고
    • Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
    • DOI 10.1126/science.1129631
    • Hollien J, Weissman JS. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Science 2006;313:104-107 (Pubitemid 44051264)
    • (2006) Science , vol.313 , Issue.5783 , pp. 104-107
    • Hollien, J.1    Weissman, J.S.2
  • 13
    • 33751333201 scopus 로고    scopus 로고
    • Substrate-Specific Translocational Attenuation during ER Stress Defines a Pre-Emptive Quality Control Pathway
    • DOI 10.1016/j.cell.2006.10.032, PII S0092867406014103
    • Kang SW, Rane NS, Kim SJ, et al. Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway. Cell 2006;127:999-1013 (Pubitemid 44803063)
    • (2006) Cell , vol.127 , Issue.5 , pp. 999-1013
    • Kang, S.-W.1    Rane, N.S.2    Kim, S.J.3    Garrison, J.L.4    Taunton, J.5    Hegde, R.S.6
  • 15
    • 0033118409 scopus 로고    scopus 로고
    • Complexes containing activating transcription factor (ATF)/cAMP- responsive-element-binding protein (CREB) interact with the CCAAT/enhancer- binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
    • DOI 10.1042/0264-6021:3390135
    • Fawcett TW, Martindale JL, Guyton KZ, et al. Complexes containing activating transcription factor (ATF)/cAMP responsive-element-binding protein (CREB) interact with the CCAAT/ enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem J 1999;339(Pt 1):135-141 (Pubitemid 29179300)
    • (1999) Biochemical Journal , vol.339 , Issue.1 , pp. 135-141
    • Fawcett, T.W.1    Martindale, J.L.2    Guyton, K.Z.3    Hai, T.4    Holbrook, N.J.5
  • 17
    • 34548172495 scopus 로고    scopus 로고
    • Transcriptional Induction of Mammalian ER Quality Control Proteins Is Mediated by Single or Combined Action of ATF6α and XBP1
    • DOI 10.1016/j.devcel.2007.07.018, PII S1534580707003000
    • Yamamoto K, Sato T, Matsui T, et al. Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1. Dev Cell 2007;13:365-376 (Pubitemid 47308680)
    • (2007) Developmental Cell , vol.13 , Issue.3 , pp. 365-376
    • Yamamoto, K.1    Sato, T.2    Matsui, T.3    Sato, M.4    Okada, T.5    Yoshida, H.6    Harada, A.7    Mori, K.8
  • 18
    • 0032525990 scopus 로고    scopus 로고
    • A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells
    • Tirasophon W, Welihinda AA, Kaufman RJ. A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (Ire1p) in mammalian cells. Genes Dev 1998;12:1812-1824 (Pubitemid 28304334)
    • (1998) Genes and Development , vol.12 , Issue.12 , pp. 1812-1824
    • Tirasophon, W.1    Welihinda, A.A.2    Kaufman, R.J.3
  • 19
    • 0032190546 scopus 로고    scopus 로고
    • Cloning of mammalian Ire1 reveals diversity in the ER stress responses
    • DOI 10.1093/emboj/17.19.5708
    • Wang XZ, Harding HP, Zhang Y, et al. Cloning of mammalian Ire1 reveals diversity in the ER stress responses. EMBO J 1998;17:5708-5717 (Pubitemid 28445982)
    • (1998) EMBO Journal , vol.17 , Issue.19 , pp. 5708-5717
    • Wang, X.-Z.1    Harding, H.P.2    Zhang, Y.3    Jolicoeur, E.M.4    Kuroda, M.5    Ron, D.6
  • 20
    • 31944450850 scopus 로고    scopus 로고
    • Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
    • DOI 10.1083/jcb.200507057
    • Oda Y, Okada T, Yoshida H, et al. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J Cell Biol 2006;172:383-393 (Pubitemid 43187935)
    • (2006) Journal of Cell Biology , vol.172 , Issue.3 , pp. 383-393
    • Oda, Y.1    Okada, T.2    Yoshida, H.3    Kaufman, R.J.4    Nagata, K.5    Mori, K.6
  • 22
    • 0036270698 scopus 로고    scopus 로고
    • Retro-translocation of proteins from the endoplasmic reticulum into the cytosol
    • DOI 10.1038/nrm780
    • Tsai B, Ye Y, Rapoport TA. Retro-translocation of proteins from the endoplasmic reticulum into the cytosol. Nat Rev Mol Cell Biol 2002;3:246-255 (Pubitemid 34619260)
    • (2002) Nature Reviews Molecular Cell Biology , vol.3 , Issue.4 , pp. 246-255
    • Tsai, B.1    Ye, Y.2    Rapoport, T.A.3
  • 23
    • 0035947773 scopus 로고    scopus 로고
    • Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
    • DOI 10.1083/jcb.153.5.1061
    • Nishikawa SI, Fewell SW, Kato Y, et al. Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation. J Cell Biol 2001;153:1061-1070 (Pubitemid 34289244)
    • (2001) Journal of Cell Biology , vol.153 , Issue.5 , pp. 1061-1069
    • Nishikawa, S.-I.1    Fewell, S.W.2    Kato, Y.3    Brodsky, J.L.4    Endo, T.5
  • 24
    • 0033611127 scopus 로고    scopus 로고
    • Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase
    • DOI 10.1083/jcb.147.7.1443
    • Gillece P, Luz JM, Lennarz WJ, et al. Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase. J Cell Biol 1999;147:1443-1456 (Pubitemid 30027400)
    • (1999) Journal of Cell Biology , vol.147 , Issue.7 , pp. 1443-1456
    • Gillece, P.1    Luz, J.M.2    Lennarz, W.J.3    De La Cruz, F.J.4    Romisch, K.5
  • 26
    • 48249117110 scopus 로고    scopus 로고
    • ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER
    • Ushioda R, Hoseki J, Araki K, et al. ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER. Science 2008;321:569-572
    • (2008) Science , vol.321 , pp. 569-572
    • Ushioda, R.1    Hoseki, J.2    Araki, K.3
  • 27
    • 0035818999 scopus 로고    scopus 로고
    • The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
    • DOI 10.1038/414652a
    • Ye Y, Meyer HH, Rapoport TA. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol. Nature 2001;414:652-656 (Pubitemid 33151262)
    • (2001) Nature , vol.414 , Issue.6864 , pp. 652-656
    • Ye, Y.1    Meyer, H.H.2    Rapoport, T.A.3
  • 28
    • 34249069585 scopus 로고    scopus 로고
    • Real-Time Fluorescence Detection of ERAD Substrate Retrotranslocation in a Mammalian in Vitro System
    • DOI 10.1016/j.cell.2007.03.046, PII S0092867407005156
    • Wahlman J, DeMartino GN, Skach WR, et al. Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system. Cell 2007;129:943-955 (Pubitemid 46802700)
    • (2007) Cell , vol.129 , Issue.5 , pp. 943-955
    • Wahlman, J.1    Demartino, G.N.2    Skach, W.R.3    Bulleid, N.J.4    Brodsky, J.L.5    Johnson, A.6
  • 29
    • 0032728066 scopus 로고    scopus 로고
    • Posttranslational protein translocation across the membrane of the endoplasmic reticulum
    • DOI 10.1515/BC.1999.145
    • Rapoport TA, Matlack KE, Plath K, et al. Posttranslational protein translocation across the membrane of the endoplasmic reticulum. Biol Chem 1999;380:1143-1150 (Pubitemid 29516402)
    • (1999) Biological Chemistry , vol.380 , Issue.10 , pp. 1143-1150
    • Rapoport, T.A.1    Matlack, K.E.S.2    Plath, K.3    Misselwitz, B.4    Staeck, O.5
  • 31
    • 0033382189 scopus 로고    scopus 로고
    • The engagement of Sec61p in the ER dislocation process
    • Zhou M, Schekman R. The engagement of Sec61p in the ER dislocation process. Mol Cell 1999;4:925-934 (Pubitemid 30054899)
    • (1999) Molecular Cell , vol.4 , Issue.6 , pp. 925-934
    • Zhou, M.1    Schekman, R.2
  • 32
    • 3042677637 scopus 로고    scopus 로고
    • A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
    • DOI 10.1038/nature02656
    • Ye Y, Shibata Y, Yun C, et al. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 2004;429:841-847 (Pubitemid 38843292)
    • (2004) Nature , vol.429 , Issue.6994 , pp. 841-847
    • Ye, Y.1    Shibata, Y.2    Yun, C.3    Ron, D.4    Rapoport, T.A.5
  • 33
    • 3042616595 scopus 로고    scopus 로고
    • A membrane protein required for dislocation of misfolded proteins from the ER
    • DOI 10.1038/nature02592
    • Lilley BN, Ploegh HL. A membrane protein required for dislocation of misfolded proteins from the ER. Nature 2004;429:834-840 (Pubitemid 38843291)
    • (2004) Nature , vol.429 , Issue.6994 , pp. 834-840
    • Lilley, B.N.1    Ploegh, H.L.2
  • 34
    • 26244431960 scopus 로고    scopus 로고
    • Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
    • DOI 10.1073/pnas.0505014102
    • Lilley BN, Ploegh HL. Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. Proc Natl Acad Sci USA 2005;102:14296-14301 (Pubitemid 41429692)
    • (2005) Proceedings of the National Academy of Sciences of the United States of America , vol.102 , Issue.40 , pp. 14296-14301
    • Lilley, B.N.1    Ploegh, H.L.2
  • 36
    • 4444253303 scopus 로고    scopus 로고
    • Survival and apoptosis signals in ER stress: The role of protein kinases
    • DOI 10.1016/j.jchemneu.2004.05.004, PII S0891061804000547
    • Kadowaki H, Nishitoh H, Ichijo H. Survival and apoptosis signals in ER stress: the role of protein kinases. J Chem Neuroanat 2004;28:93-100 (Pubitemid 39195254)
    • (2004) Journal of Chemical Neuroanatomy , vol.28 , Issue.1-2 , pp. 93-100
    • Kadowaki, H.1    Nishitoh, H.2    Ichijo, H.3
  • 37
    • 1842843855 scopus 로고    scopus 로고
    • Roles of CHOP/GADD153 in endoplasmic reticulum stress
    • DOI 10.1038/sj.cdd.4401373
    • Oyadomari S, Mori M. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 2004;11:381-389 (Pubitemid 38489416)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 381-389
    • Oyadomari, S.1    Mori, M.2
  • 39
    • 0027362667 scopus 로고
    • Investigation of the subcellular distribution of the bcl-2 oncoprotein: Residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes
    • Krajewski S, Tanaka S, Takayama S, et al. Investigation of the subcellular distribution of the bcl-2 oncoprotein: residence in the nuclear envelope, endoplasmic reticulum, and outer mitochondrial membranes. Cancer Res 1993;53:4701-4714 (Pubitemid 23304404)
    • (1993) Cancer Research , vol.53 , Issue.18 , pp. 4701-4714
    • Krajewski, S.1    Tanaka, S.2    Takayama, S.3    Schibler, M.J.4    Fenton, W.5    Reed, J.C.6
  • 40
    • 1442359853 scopus 로고    scopus 로고
    • There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum
    • DOI 10.1016/j.bbamcr.2003.07.001, PII S0167488903001782
    • Annis MG, Yethon JA, Leber B, et al. There is more to life and death than mitochondria: Bcl-2 proteins at the endoplasmic reticulum. Biochim Biophys Acta 2004;1644:115-123 (Pubitemid 38281268)
    • (2004) Biochimica et Biophysica Acta - Molecular Cell Research , vol.1644 , Issue.2-3 , pp. 115-123
    • Annis, M.G.1    Yethon, J.A.2    Leber, B.3    Andrews, D.W.4
  • 41
    • 0344897663 scopus 로고    scopus 로고
    • Bcl-2 on the endoplasmic reticulum: Protecting the mitochondria from a distance
    • DOI 10.1242/jcs.00829
    • Thomenius MJ, Distelhorst CW. Bcl-2 on the endoplasmic reticulum: protecting the mitochondria from a distance. J Cell Sci 2003;116:4493-4499 (Pubitemid 37461604)
    • (2003) Journal of Cell Science , vol.116 , Issue.22 , pp. 4493-4499
    • Thomenius, M.J.1    Distelhorst, C.W.2
  • 42
    • 54949135707 scopus 로고    scopus 로고
    • The endoplasmic reticulum in apoptosis and autophagy: Role of the BCL-2 protein family
    • Heath-Engel HM, Chang NC, Shore GC. The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family. Oncogene 2008;27:6419-6433
    • (2008) Oncogene , vol.27 , pp. 6419-6433
    • Heath-Engel, H.M.1    Chang, N.C.2    Shore, G.C.3
  • 43
    • 0035876483 scopus 로고    scopus 로고
    • BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
    • DOI 10.1101/gad.897601
    • Zong WX, Lindsten T, Ross AJ, et al. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. Genes Dev 2001;15:1481-1486 (Pubitemid 32552527)
    • (2001) Genes and Development , vol.15 , Issue.12 , pp. 1481-1486
    • Zong, W.-X.1    Lindsten, T.2    Ross, A.J.3    MacGregor, G.R.4    Thompson, C.B.5
  • 45
    • 0034698878 scopus 로고    scopus 로고
    • Cross-talk between two cysteine protease families: Activation of caspase-12 by calpain in apoptosis
    • DOI 10.1083/jcb.150.4.887
    • Nakagawa T, Yuan J. Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis. J Cell Biol 2000;150:887-894 (Pubitemid 30663424)
    • (2000) Journal of Cell Biology , vol.150 , Issue.4 , pp. 887-894
    • Nakagawa, T.1    Yuan, J.2
  • 46
    • 0032080004 scopus 로고    scopus 로고
    • Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver
    • DOI 10.1074/jbc.273.18.10815
    • Chandler JM, Cohen GM, MacFarlane M. Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver. J Biol Chem 1998;273:10815-10818 (Pubitemid 28204912)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.18 , pp. 10815-10818
    • Chandler, J.M.1    Cohen, G.M.2    MacFarlane, M.3
  • 48
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • DOI 10.1038/47513
    • Nakagawa T, Zhu H, Morishima N, et al. Caspase-12 mediates endoplasmic reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 2000;403:98-103 (Pubitemid 30038529)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3    Li, E.4    Xu, J.5    Yankner, B.A.6    Yuan, J.7
  • 51
    • 43149114461 scopus 로고    scopus 로고
    • Requirement of reactive oxygen species dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage
    • Noguchi T, Ishii K, Fukutomi H, et al. Requirement of reactive oxygen species dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J Biol Chem 2008;283:7657-7665
    • (2008) J Biol Chem , vol.283 , pp. 7657-7665
    • Noguchi, T.1    Ishii, K.2    Fukutomi, H.3
  • 53
    • 0032544309 scopus 로고    scopus 로고
    • Activation of Apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx
    • DOI 10.1126/science.281.5384.1860
    • Chang HY, Nishitoh H, Yang X, et al. Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx. Science 1998;281:1860-1863 (Pubitemid 28450508)
    • (1998) Science , vol.281 , Issue.5384 , pp. 1860-1863
    • Chang, H.Y.1    Nishitoh, H.2    Yang, X.3    Ichijo, H.4    Baltimore, D.5
  • 54
    • 0032080283 scopus 로고    scopus 로고
    • Mammalian thioredoxin is a direct inhibitor of apoptosis signal regulating kinase (ASK) 1
    • Saitoh M, Nishitoh H, Fujii M, et al. Mammalian thioredoxin is a direct inhibitor of apoptosis signal regulating kinase (ASK) 1. EMBO J 1998;17:2596-2606
    • (1998) EMBO J , vol.17 , pp. 2596-2606
    • Saitoh, M.1    Nishitoh, H.2    Fujii, M.3
  • 57
    • 0037115761 scopus 로고    scopus 로고
    • Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): A distinct pathway from those of chemically induced and receptor-mediated apoptosis
    • DOI 10.1042/BJ20020101
    • Saeki K, Kobayashi N, Inazawa Y, et al. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor mediated apoptosis. Biochem J 2002;368:705-720 (Pubitemid 36042672)
    • (2002) Biochemical Journal , vol.368 , Issue.3 , pp. 705-720
    • Saeki, K.1    Kobayashi, N.2    Inazawa, Y.3    Zhang, H.4    Nishitoh, H.5    Ichijo, H.6    Saeki, K.7    Isemura, M.8    Yuo, A.9
  • 58
    • 36849043546 scopus 로고    scopus 로고
    • Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
    • DOI 10.1128/MCB.00227-07
    • Fujino G, Noguchi T, Matsuzawa A, et al. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol 2007;27:8152-8163 (Pubitemid 350234230)
    • (2007) Molecular and Cellular Biology , vol.27 , Issue.23 , pp. 8152-8163
    • Fujino, G.1    Noguchi, T.2    Matsuzawa, A.3    Yamauchi, S.4    Saitoh, M.5    Takeda, K.6    Ichijo, H.7
  • 59
    • 27744559915 scopus 로고    scopus 로고
    • Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death
    • DOI 10.1074/jbc.M506771200
    • Noguchi T, Takeda K, Matsuzawa A, et al. Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalosome is essential for oxidative stress-induced cell death. J Biol Chem 2005;280:37033-37040 (Pubitemid 41587787)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.44 , pp. 37033-37040
    • Noguchi, T.1    Takeda, K.2    Matsuzawa, A.3    Saegusa, K.4    Nakano, H.5    Gohda, J.6    Inoue, J.-I.7    Ichijo, H.8
  • 60
    • 0034723235 scopus 로고    scopus 로고
    • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
    • DOI 10.1126/science.287.5453.664
    • Urano F, Wang X, Bertolotti A, et al. Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 2000;287:664-666 • This paper demonstrates that IRE1 mediates ER stress-induced JNK activation. (Pubitemid 30070916)
    • (2000) Science , vol.287 , Issue.5453 , pp. 664-666
    • Urano, F.1    Wang, X.2    Bertolotti, A.3    Zhang, Y.4    Chung, P.5    Harding, H.P.6    Ron, D.7
  • 64
    • 0029938805 scopus 로고    scopus 로고
    • Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase
    • Wang XZ, Ron D. Stress-induced phosphorylation and activation of the transcription factor CHOP (GADD153) by p38 MAP kinase. Science 1996;272:1347-1349 (Pubitemid 26199977)
    • (1996) Science , vol.272 , Issue.5266 , pp. 1347-1349
    • Wang, X.1    Ron, D.2
  • 65
    • 0035936804 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis: Unfolding the toxicity of the misfolded
    • DOI 10.1016/S0092-8674(01)00244-6
    • Julien JP. Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded. Cell 2001;104:581-591 (Pubitemid 32201952)
    • (2001) Cell , vol.104 , Issue.4 , pp. 581-591
    • Julien, J.-P.1
  • 67
    • 33645798615 scopus 로고    scopus 로고
    • Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model
    • Kikuchi H, Almer G, Yamashita S, et al. Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proc Natl Acad Sci USA 2006;103:6025-6030
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 6025-6030
    • Kikuchi, H.1    Almer, G.2    Yamashita, S.3
  • 70
    • 19444374567 scopus 로고    scopus 로고
    • Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice
    • Holasek SS, Wengenack TM, Kandimalla KK, et al. Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. Brain Res 2005;1045:185-198
    • (2005) Brain Res , vol.1045 , pp. 185-198
    • Holasek, S.S.1    Wengenack, T.M.2    Kandimalla, K.K.3
  • 72
    • 5644242311 scopus 로고    scopus 로고
    • Activation of programmed cell death markers in ventral horn motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in a transgenic mouse model
    • DOI 10.1016/j.brainres.2004.08.054, PII S0006899304013605
    • Wengenack TM, Holasek SS, Montano CM, et al. Activation of programmed cell death markers in ventral horn motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in a transgenic mouse model. Brain Res 2004;1027:73-86 (Pubitemid 39370997)
    • (2004) Brain Research , vol.1027 , Issue.1-2 , pp. 73-86
    • Wengenack, T.M.1    Holasek, S.S.2    Montano, C.M.3    Gregor, D.4    Curran, G.L.5    Poduslo, J.F.6
  • 73
    • 0031761706 scopus 로고    scopus 로고
    • Protein precipitation: A common etiology in neurodegenerative disorders?
    • Kakizuka A. Protein precipitation: a common etiology in neurodegenerative disorders? Trends Genet 1998;14:396-402
    • (1998) Trends Genet , vol.14 , pp. 396-402
    • Kakizuka, A.1
  • 77
    • 57749116408 scopus 로고    scopus 로고
    • Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity
    • Duennwald ML, Lindquist S. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes Dev 2008;22:3308-3319
    • (2008) Genes Dev , vol.22 , pp. 3308-3319
    • Duennwald, M.L.1    Lindquist, S.2
  • 78
    • 42449161835 scopus 로고    scopus 로고
    • ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease
    • Arning L, Monte D, Hansen W, et al. ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease. J Mol Med 2008;86:485-490
    • (2008) J Mol Med , vol.86 , pp. 485-490
    • Arning, L.1    Monte, D.2    Hansen, W.3
  • 81
    • 1842562209 scopus 로고    scopus 로고
    • An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease
    • DOI 10.1038/sj.emboj.7600049
    • Onuki R, Bando Y, Suyama E, et al. An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease. EMBO J 2004;23:959-968 (Pubitemid 38418762)
    • (2004) EMBO Journal , vol.23 , Issue.4 , pp. 959-968
    • Onuki, R.1    Bando, Y.2    Suyama, E.3    Katayama, T.4    Kawasaki, H.5    Baba, T.6    Tohyama, M.7    Taira, K.8
  • 82
    • 33646376968 scopus 로고    scopus 로고
    • A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease
    • Saltini G, Dominici R, Lovati C, et al. A novel polymorphism in SEL1L confers susceptibility to Alzheimer's disease. Neurosci Lett 2006;398:53-58
    • (2006) Neurosci Lett , vol.398 , pp. 53-58
    • Saltini, G.1    Dominici, R.2    Lovati, C.3
  • 83
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid β protein toxicity
    • DOI 10.1016/0092-8674(94)90131-7
    • Behl C, Davis JB, Lesley R, et al. Hydrogen peroxide mediates amyloid β protein toxicity. Cell 1994;77:817-827 (Pubitemid 24187680)
    • (1994) Cell , vol.77 , Issue.6 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 89
    • 0034680913 scopus 로고    scopus 로고
    • Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity
    • DOI 10.1074/jbc.C000447200
    • Imai Y, Soda M, Takahashi R. Parkin suppresses unfolded protein stress-induced cell death through its E3 ubiquitin-protein ligase activity. J Biol Chem 2000;275:35661-35664 (Pubitemid 30841094)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.46 , pp. 35661-35664
    • Imai, Y.1    Soda, M.2    Takahashi, R.3
  • 90
    • 0036345454 scopus 로고    scopus 로고
    • CHIP is associated with Parkin, a gene responsible for familial Parkinson's Disease, and enhances its ubiquitin ligase activity
    • DOI 10.1016/S1097-2765(02)00583-X
    • Imai Y, Soda M, Hatakeyama S, et al. CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity. Mol Cell 2002;10:55-67 (Pubitemid 34876562)
    • (2002) Molecular Cell , vol.10 , Issue.1 , pp. 55-67
    • Imai, Y.1    Soda, M.2    Hatakeyama, S.3    Akagi, T.4    Hashikawa, T.5    Nakayama, K.-I.6    Takahashi, R.7
  • 91
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • DOI 10.1016/S0092-8674(01)00407-X
    • Imai Y, Soda M, Inoue H, et al. An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 2001;105:891-902 (Pubitemid 32635090)
    • (2001) Cell , vol.105 , Issue.7 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hattori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 93
    • 0028127058 scopus 로고
    • Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
    • DOI 10.1016/0306-4522(94)90566-5
    • Walkinshaw G, Waters CM. Neurotoxin induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neuroscience 1994;63:975-987 (Pubitemid 24366149)
    • (1994) Neuroscience , vol.63 , Issue.4 , pp. 975-987
    • Walkinshaw, G.1    Waters, C.M.2
  • 95
  • 99
    • 59449108481 scopus 로고    scopus 로고
    • Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1
    • Kim I, Shu CW, Xu W, et al. Chemical biology investigation of cell death pathways activated by endoplasmic reticulum stress reveals cytoprotective modulators of ASK1. J Biol Chem 2009;284:1593-1603
    • (2009) J Biol Chem , vol.284 , pp. 1593-1603
    • Kim, I.1    Shu, C.W.2    Xu, W.3


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