An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease

EMBO Journal

Volumn 23, Issue 4, 2004, Pages 959-968

  Onuki, Reiko ^a,b,c   Bando, Yoshio ^d,e,f   Suyama, Eigo ^a,b,g   Katayama, Taiichi ^e,f,h   Kawasaki, Hiroaki ^a,b   Baba, Tadashi ^c   Tohyama, Masaya ^e,f   Taira, Kazunari ^a,b  

^a NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF TSUKUBA   (Japan)

^d ASAHIKAWA MEDICAL COLLEGE   (Japan)

^e OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^f JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^g GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^h Ctr Res Neurodigenerative Dis   (Canada)

Author keywords

Alzheimer's disease; ER stress; Neuronal degenerative diseases; PKR; Ribozyme

Indexed keywords

DOUBLE STRANDED RNA; PROTEIN KINASE; RIBOZYME; RNA DEPENDENT PROTEIN KINASE; TUNICAMYCIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; AUTOPSY; BRAIN TISSUE; CALCIUM HOMEOSTASIS; CELL NUCLEUS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME MECHANISM; HUMAN; HUMAN CELL; NEUROPATHOLOGY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PHOSPHORYLATION; STRESS;

AGED; ALZHEIMER DISEASE; APOPTOSIS; BRAIN; CELL NUCLEUS; CYTOPLASM; EIF-2 KINASE; ENDOPLASMIC RETICULUM; HUMANS; PHOSPHORYLATION; RNA, CATALYTIC; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUNICAMYCIN;

EID: 1842562209     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600049     Document Type: Article

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