Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): A distinct pathway from those of chemically induced and receptor-mediated apoptosis

Biochemical Journal

Volumn 368, Issue 3, 2002, Pages 705-720

  Saeki, Koichi ^a   Kobayashi, Norihiko ^a   Inazawa, Yuko ^a   Zhang, Hong ^a   Nishitoh, Hideki ^b   Ichijo, Hidenori ^b   Saeki, Kumiko ^a   Isemura, Mamoru ^c   Yuo, Akira ^a  

^a NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

Apoptosis regulating kinase 1; Caspase; Polyphenol; Reactive oxygen species; Reduction oxidation

Indexed keywords

CHEMICAL ACTIVATION; ENZYME INHIBITION; ENZYME KINETICS; OXIDATION; PROTEINS; TUMORS;

LEUKAEMIA;

ANIMAL CELL CULTURE;

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CASPASE 3; CASPASE 9; EPIGALLOCATECHIN GALLATE; ETOPOSIDE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE INHIBITOR; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TUMOR NECROSIS FACTOR;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; HUMAN; HUMAN CELL; LEUKEMIA; OXIDATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CASPASE 8; CASPASE 9; CASPASES; CATECHIN; CELL DEATH; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; ENZYME INHIBITORS; ETOPOSIDE; FLAVONOIDS; FLOW CYTOMETRY; GLUTATHIONE; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE KINASE 5; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NF-KAPPA B; NUCLEIC ACID SYNTHESIS INHIBITORS; OXIDATION-REDUCTION; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHENOLS; POLYMERS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; U937 CELLS; URINARY PLASMINOGEN ACTIVATOR;

ANIMALIA;

EID: 0037115761     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020101     Document Type: Article

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