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Volumn 48, Issue 6, 2009, Pages 558-570

Toll-like receptors and dermatology

Author keywords

[No Author keywords available]

Indexed keywords

AGATOLIMOD; ALPHA INTERFERON; BROPIRIMINE; CELL MEMBRANE PROTEIN; CHLOROQUINE; HEAT SHOCK PROTEIN; IMIDAZOQUINOLINE DERIVATIVE; IMIQUIMOD; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; LOXORIBINE; PROTEIN UNC 93B; RESIQUIMOD; RETINOIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 8; UNCLASSIFIED DRUG;

EID: 66849099662     PISSN: 00119059     EISSN: 13654632     Source Type: Journal    
DOI: 10.1111/j.1365-4632.2009.04111.x     Document Type: Review
Times cited : (9)

References (129)
  • 1
    • 0029730738 scopus 로고    scopus 로고
    • A conserved signaling pathway: The Drosophila toll-dorsal pathway
    • Belvin MP, Anderson KV. A conserved signaling pathway: The Drosophila toll-dorsal pathway. Annu Rev Cell Biol 1996; 12: 393-416.
    • (1996) Annu Rev Cell Biol , vol.12 , pp. 393-416
    • Belvin, M.P.1    Anderson, K.V.2
  • 2
    • 33646147362 scopus 로고    scopus 로고
    • Toll-like receptor function and signaling
    • Kaisho T, Akira S. Toll-like receptor function and signaling. J Allergy Clin Immunol 2006; 117: 979-987.
    • (2006) J Allergy Clin Immunol , vol.117 , pp. 979-987
    • Kaisho, T.1    Akira, S.2
  • 3
    • 0021603716 scopus 로고
    • Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA
    • Anderson KV, Nusslein-Volhard C. Information for the dorsal-ventral pattern of the Drosophila embryo is stored as maternal mRNA. Nature 1984; 311: 223-227.
    • (1984) Nature , vol.311 , pp. 223-227
    • Anderson, K.V.1    Nusslein-Volhard, C.2
  • 4
    • 0029100989 scopus 로고
    • Nobel committee rewards pioneers of development studies in fruitflies
    • Cohen B. Nobel committee rewards pioneers of development studies in fruitflies. Nature 1995; 377: 465.
    • (1995) Nature , vol.377 , pp. 465
    • Cohen, B.1
  • 5
    • 0024299087 scopus 로고
    • The toll gene in Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
    • Hashimoto C, Hudson K, Anderson K. The toll gene in Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 1988; 52: 169-179.
    • (1988) Cell , vol.52 , pp. 169-179
    • Hashimoto, C.1    Hudson, K.2    Anderson, K.3
  • 6
    • 0030595339 scopus 로고    scopus 로고
    • The dorso ventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre B, Nicholas E, Michaut L, et al. The dorso ventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 1996; 86: 973-983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicholas, E.2    Michaut, L.3
  • 7
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptative immunity
    • Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptative immunity. Nature 1997; 338: 394-397.
    • (1997) Nature , vol.338 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 9
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 10
    • 33646183566 scopus 로고    scopus 로고
    • Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large
    • Beutler B, Jiang Z, Georgel P, et al. Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large. Annu Rev Immunol 2006; 24: 353-389.
    • (2006) Annu Rev Immunol , vol.24 , pp. 353-389
    • Beutler, B.1    Jiang, Z.2    Georgel, P.3
  • 11
    • 33646518605 scopus 로고    scopus 로고
    • Toll-like receptors: Applications to dermatologic disease
    • Kang SSW, Kauls LS, Gaspari AA. Toll-like receptors: Applications to dermatologic disease. J Am Acad Dermatol 2006; 54: 951-983.
    • (2006) J Am Acad Dermatol , vol.54 , pp. 951-983
    • Kang, S.S.W.1    Kauls, L.S.2    Gaspari, A.A.3
  • 12
    • 0034456693 scopus 로고    scopus 로고
    • Three novel mammalian toll-like receptors: Gene structure, expression, and evolution
    • Du X, Poltorak A, Wei Y, Beutler B. Three novel mammalian toll-like receptors: Gene structure, expression, and evolution. Eur Cytokine Netw 2000; 11: 362-371.
    • (2000) Eur Cytokine Netw , vol.11 , pp. 362-371
    • Du, X.1    Poltorak, A.2    Wei, Y.3    Beutler, B.4
  • 14
    • 39549123040 scopus 로고    scopus 로고
    • Toll-like receptor polymorphisms and susceptibility to human disease
    • Mish EA, Hawn TR. Toll-like receptor polymorphisms and susceptibility to human disease. Clin Sci 2008; 114: 347-360.
    • (2008) Clin Sci , vol.114 , pp. 347-360
    • Mish, E.A.1    Hawn, T.R.2
  • 15
    • 34548815890 scopus 로고    scopus 로고
    • Toll-like receptors in dermatology
    • Mempel M, Kalai BN, Ollet M, et al. Toll-like receptors in dermatology. Dermatol Clin 2007; 25: 531-540.
    • (2007) Dermatol Clin , vol.25 , pp. 531-540
    • Mempel, M.1    Kalai, B.N.2    Ollet, M.3
  • 16
    • 20144389424 scopus 로고    scopus 로고
    • Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes
    • Kollisch G, Kalali BN, Voelcker V, et al. Various members of the Toll-like receptor family contribute to the innate immune response of human epidermal keratinocytes. Immunology 2005; 114: 531-541.
    • (2005) Immunology , vol.114 , pp. 531-541
    • Kollisch, G.1    Kalali, B.N.2    Voelcker, V.3
  • 17
    • 10744222928 scopus 로고    scopus 로고
    • Toll-like receptor expression in human keratinocytes: Nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent
    • Mempel M, Voelcker V, Kollisch G, et al. Toll-like receptor expression in human keratinocytes: Nuclear factor kappaB controlled gene activation by Staphylococcus aureus is toll-like receptor 2 but not toll-like receptor 4 or platelet activating factor receptor dependent. J Invest Dermatol 2003; 121: 1389-1396.
    • (2003) J Invest Dermatol , vol.121 , pp. 1389-1396
    • Mempel, M.1    Voelcker, V.2    Kollisch, G.3
  • 18
    • 20844445114 scopus 로고    scopus 로고
    • TGF-alpha regulates TLR expression and function on epidermal keratinocytes
    • Miller LS, Sorensen OE, Liu TP, et al. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. J Immunol 2005; 174: 6137-6143.
    • (2005) J Immunol , vol.174 , pp. 6137-6143
    • Miller, L.S.1    Sorensen, O.E.2    Liu, T.P.3
  • 19
    • 0038281539 scopus 로고    scopus 로고
    • Expression and function of Toll-like receptors 2 and 4 in human keratinocytes
    • Pivarcsi A, Bodai L, Rethi B, et al. Expression and function of Toll-like receptors 2 and 4 in human keratinocytes. Int Immunol 2003; 15: 721-730.
    • (2003) Int Immunol , vol.15 , pp. 721-730
    • Pivarcsi, A.1    Bodai, L.2    Rethi, B.3
  • 20
    • 0037791839 scopus 로고    scopus 로고
    • Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type 1 polarized phenotype in dendritic cells: Role of keratinocyte-derived-tumor necrosis factor alpha, type I interferons and interleukin-18
    • Lebre MC, Antons JC, Kalinski P, et al. Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type 1 polarized phenotype in dendritic cells: Role of keratinocyte-derived-tumor necrosis factor alpha, type I interferons and interleukin-18. J Invest Dermatol 2003; 120: 990-997.
    • (2003) J Invest Dermatol , vol.120 , pp. 990-997
    • Lebre, M.C.1    Antons, J.C.2    Kalinski, P.3
  • 21
    • 33745324477 scopus 로고    scopus 로고
    • TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response
    • Renn CN, Sanchez DJ, Ochoa MT, et al. TLR activation of Langerhans cell-like dendritic cells triggers an antiviral immune response. J Immunol 2006; 177: 298-305.
    • (2006) J Immunol , vol.177 , pp. 298-305
    • Renn, C.N.1    Sanchez, D.J.2    Ochoa, M.T.3
  • 22
    • 41949140086 scopus 로고    scopus 로고
    • Human melanocytes express functional Toll-like receptor 4
    • Ahn JH, Park TJ, Jin SH, et al. Human melanocytes express functional Toll-like receptor 4. Exp Dermatol 2008; 17: 412-417.
    • (2008) Exp Dermatol , vol.17 , pp. 412-417
    • Ahn, J.H.1    Park, T.J.2    Jin, S.H.3
  • 23
    • 61449262031 scopus 로고    scopus 로고
    • Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells
    • in press
    • Dearman RJ, Cumberbatch M, Maxwell G, et al. Toll-like receptor ligand activation of murine bone marrow-derived dendritic cells. Immunology 2009; in press.
    • (2009) Immunology
    • Dearman, R.J.1    Cumberbatch, M.2    Maxwell, G.3
  • 25
    • 0642337440 scopus 로고    scopus 로고
    • Pathogenesis of acne: Research advances
    • Harper JC, Thiboutot DM. Pathogenesis of acne: Research advances. Adv Dermatol 2003; 19: 1-10.
    • (2003) Adv Dermatol , vol.19 , pp. 1-10
    • Harper, J.C.1    Thiboutot, D.M.2
  • 26
    • 0029134833 scopus 로고
    • Introduction of proinflammatory cytokines by a soluble factor of Propionibacteruim acnes: Implications for chronic inflammatory acne
    • Vowels BR, Yang S, Leyden JJ. Introduction of proinflammatory cytokines by a soluble factor of Propionibacteruim acnes: Implications for chronic inflammatory acne. Infect Immun 1995; 63: 3158-3165.
    • (1995) Infect Immun , vol.63 , pp. 3158-3165
    • Vowels, B.R.1    Yang, S.2    Leyden, J.J.3
  • 27
    • 0036681834 scopus 로고    scopus 로고
    • Activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses
    • Kim J, Ochoa MT, Krutzik SR, et al. Activation of Toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol 2002; 169: 1535-1541.
    • (2002) J Immunol , vol.169 , pp. 1535-1541
    • Kim, J.1    Ochoa, M.T.2    Krutzik, S.R.3
  • 28
    • 33749130874 scopus 로고    scopus 로고
    • Toll-like receptors in acne vulgaris
    • Heymann WR. Toll-like receptors in acne vulgaris. J Am Acad Dermatol 2006; 55: 691-692.
    • (2006) J Am Acad Dermatol , vol.55 , pp. 691-692
    • Heymann, W.R.1
  • 29
    • 14044257262 scopus 로고    scopus 로고
    • Cutting edge: All-trans retinoic acid down-regulates TLR2 expression and function
    • Lin PT, Krutzik SR, Kim J, et al. Cutting edge: All-trans retinoic acid down-regulates TLR2 expression and function. J Immunol 2005; 174: 2467-2470.
    • (2005) J Immunol , vol.174 , pp. 2467-2470
    • Lin, P.T.1    Krutzik, S.R.2    Kim, J.3
  • 30
    • 0742272507 scopus 로고    scopus 로고
    • The role of Toll-like receptors in combating mycobacteria
    • Krutzik SR, Modlin RL. The role of Toll-like receptors in combating mycobacteria. Semin Immunol 2004; 16: 35-41.
    • (2004) Semin Immunol , vol.16 , pp. 35-41
    • Krutzik, S.R.1    Modlin, R.L.2
  • 31
    • 0038578610 scopus 로고    scopus 로고
    • Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
    • Krutzik SR, Ochoa MT, Sieling PA, et al. Activation and regulation of Toll-like receptors 2 and 1 in human leprosy. Nat Med 2003; 9: 525-532.
    • (2003) Nat Med , vol.9 , pp. 525-532
    • Krutzik, S.R.1    Ochoa, M.T.2    Sieling, P.A.3
  • 32
    • 48949118047 scopus 로고    scopus 로고
    • Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction
    • Misch EA, Macdonald M, Ranjit C, et al. Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction. Plos Negl Trop Dis 2008; 2: E231.
    • (2008) Plos Negl Trop Dis , vol.2
    • Misch, E.A.1    Macdonald, M.2    Ranjit, C.3
  • 33
    • 39149093678 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy
    • Bochud PY, Hawn TR, Siddiqui MR. Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy. J Infect Dis 2008; 197: 253-261.
    • (2008) J Infect Dis , vol.197 , pp. 253-261
    • Bochud, P.Y.1    Hawn, T.R.2    Siddiqui, M.R.3
  • 34
    • 0033458799 scopus 로고    scopus 로고
    • Toll-like receptor 2 mediates mycobacteria-induced proinflammatory signaling in macrophages
    • Underhill DM, Smith KD, Aderem A. Toll-like receptor 2 mediates mycobacteria-induced proinflammatory signaling in macrophages. Proc Natl Acad Sci 1999; 96: 14, 459-14, 463.
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 14-14
    • Underhill, D.M.1    Smith, K.D.2    Aderem, A.3
  • 35
    • 0034891984 scopus 로고    scopus 로고
    • Detection of Toll-like receptor 2 (TLR2) mutation in lepromatous leprosy patients
    • Kan T, Chae G. Detection of Toll-like receptor 2 (TLR2) mutation in lepromatous leprosy patients. FEMS Immunol Med Microbiol 2001; 31: 53-58.
    • (2001) FEMS Immunol Med Microbiol , vol.31 , pp. 53-58
    • Kan, T.1    Chae, G.2
  • 36
    • 0037373014 scopus 로고    scopus 로고
    • Expression of Toll-like receptor 2 on human Schwann cells: A mechanism of nerve damage in leprosy
    • Oliveira RB, Ochoa MT, Sieling PA, et al. Expression of Toll-like receptor 2 on human Schwann cells: A mechanism of nerve damage in leprosy. Infect Immun 2003; 71: 1427-1433.
    • (2003) Infect Immun , vol.71 , pp. 1427-1433
    • Oliveira, R.B.1    Ochoa, M.T.2    Sieling, P.A.3
  • 37
    • 0002112690 scopus 로고    scopus 로고
    • Treponema pallidum (syphilis)
    • In: Mandell GL, Bennet JE, Colin R, eds. 5th edn. New York: Churchill Livingstone
    • Tramont EC. Treponema pallidum (syphilis). In: Mandell GL, Bennet JE, Colin R, eds. Principles and Practice of Infectious Diseases, 5th edn. New York: Churchill Livingstone, 2000: 2474.
    • (2000) Principles and Practice of Infectious Diseases , pp. 2474
    • Tramont, E.C.1
  • 38
    • 0030065732 scopus 로고    scopus 로고
    • Primary and secondary syphilis lesions contain mRNA for TH1 cytokines
    • Van Voorhis WC, Barret LK, Koelle DM, et al. Primary and secondary syphilis lesions contain mRNA for TH1 cytokines. J Infect Dis 1996; 173: 491-495.
    • (1996) J Infect Dis , vol.173 , pp. 491-495
    • Van Voorhis, W.C.1    Barret, L.K.2    Koelle, D.M.3
  • 39
    • 0035865232 scopus 로고    scopus 로고
    • Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2
    • Hertz CJ, Kiertscher SM, Godowski PJ, et al. Microbial lipopeptides stimulate dendritic cell maturation via Toll-like receptor 2. J Immunol 2001; 166: 2444-2450.
    • (2001) J Immunol , vol.166 , pp. 2444-2450
    • Hertz, C.J.1    Kiertscher, S.M.2    Godowski, P.J.3
  • 40
    • 0037223135 scopus 로고    scopus 로고
    • Toll-like receptor 2 ligands as adjuvants for human Th1 responses
    • Sieling PA, Chung W, Duong BT, et al. Toll-like receptor 2 ligands as adjuvants for human Th1 responses. J Immunol 2003; 170: 194-200.
    • (2003) J Immunol , vol.170 , pp. 194-200
    • Sieling, P.A.1    Chung, W.2    Duong, B.T.3
  • 41
    • 0034978134 scopus 로고    scopus 로고
    • Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin
    • Moors MA, Li L, Mizel SB. Activation of interleukin-1 receptor-associated kinase by gram-negative flagellin. Infect Immun 2001; 69: 4424-4429.
    • (2001) Infect Immun , vol.69 , pp. 4424-4429
    • Moors, M.A.1    Li, L.2    Mizel, S.B.3
  • 43
    • 0029840778 scopus 로고    scopus 로고
    • Intracellular persistence of Borrelia burgdorferi in human synovial cells
    • Girschick HJ, Huppertz HI, Russmann H, et al. Intracellular persistence of Borrelia burgdorferi in human synovial cells. Rheumatol Int 1996; 16: 25-132.
    • (1996) Rheumatol Int , vol.16 , pp. 25-132
    • Girschick, H.J.1    Huppertz, H.I.2    Russmann, H.3
  • 44
    • 0030588677 scopus 로고    scopus 로고
    • Borrelia burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells
    • Wooten RM, Modur VR, McIntyre TM, et al. Borrelia burgdorferi outer membrane protein A induces nuclear translocation of nuclear factor-kappa B and inflammatory activation in human endothelial cells. J Immunol 1996; 157: 4584-4590.
    • (1996) J Immunol , vol.157 , pp. 4584-4590
    • Wooten, R.M.1    Modur, V.R.2    McIntyre, T.M.3
  • 45
    • 0028065094 scopus 로고
    • Outer surface lipoproteins of Borrelia burgdorferi stimulate nitric oxide production by the cytokine-inducible pathway
    • Ma Y, Seiler KP, Tai KF, et al. Outer surface lipoproteins of Borrelia burgdorferi stimulate nitric oxide production by the cytokine-inducible pathway. Infect Immun 1994; 62: 3663-3671.
    • (1994) Infect Immun , vol.62 , pp. 3663-3671
    • Ma, Y.1    Seiler, K.P.2    Tai, K.F.3
  • 46
    • 0029782133 scopus 로고    scopus 로고
    • Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B
    • Norgard MV, Arndt LL, Akins DR, et al. Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B. Infect Immun 1996; 64: 3845-3852.
    • (1996) Infect Immun , vol.64 , pp. 3845-3852
    • Norgard, M.V.1    Arndt, L.L.2    Akins, D.R.3
  • 47
    • 0031570026 scopus 로고    scopus 로고
    • Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophils
    • Morrison TB, Weis JH, Weis JJ. Borrelia burgdorferi outer surface protein A (OspA) activates and primes human neutrophils. J Immunol 1997; 158: 4838-4845.
    • (1997) J Immunol , vol.158 , pp. 4838-4845
    • Morrison, T.B.1    Weis, J.H.2    Weis, J.J.3
  • 48
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember KA, Godowski PJ. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 2002; 168: 554-561.
    • (2002) J Immunol , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 49
    • 0035104481 scopus 로고    scopus 로고
    • Differential expression of Toll-like receptor 2 in human cells
    • Flo TH, Halaas O, Torp S, et al. Differential expression of Toll-like receptor 2 in human cells. J Leukoc Biol 2001; 69: 474-481.
    • (2001) J Leukoc Biol , vol.69 , pp. 474-481
    • Flo, T.H.1    Halaas, O.2    Torp, S.3
  • 51
    • 0034967970 scopus 로고    scopus 로고
    • Impact of genotypic variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease in C3H/HeJ mice
    • Wang G, Ojaimi C, Iyer R, et al. Impact of genotypic variation of Borrelia burgdorferi sensu stricto on kinetics of dissemination and severity of disease in C3H/HeJ mice. Infect Immun 2001; 69: 4303-4312.
    • (2001) Infect Immun , vol.69 , pp. 4303-4312
    • Wang, G.1    Ojaimi, C.2    Iyer, R.3
  • 52
    • 33745588825 scopus 로고    scopus 로고
    • Toll-like receptors in Borrelia burgdorferi -induced inflammation
    • Singh SK, Girschick HJ. Toll-like receptors in Borrelia burgdorferi -induced inflammation. Clin Microbiol Infect 2006; 12: 705-717.
    • (2006) Clin Microbiol Infect , vol.12 , pp. 705-717
    • Singh, S.K.1    Girschick, H.J.2
  • 53
    • 0036344106 scopus 로고    scopus 로고
    • Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice
    • Alexopoulou L, Thomas V, Schnare M, et al. Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice. Nat Med 2002; 8: 878-884.
    • (2002) Nat Med , vol.8 , pp. 878-884
    • Alexopoulou, L.1    Thomas, V.2    Schnare, M.3
  • 54
    • 41649095188 scopus 로고    scopus 로고
    • Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids
    • Schröder NW, Eckert J, Stübs G, et al. Immune responses induced by spirochetal outer membrane lipoproteins and glycolipids. Immunobiology 2008; 213: 329-340.
    • (2008) Immunobiology , vol.213 , pp. 329-340
    • Schröder, N.W.1    Eckert, J.2    Stübs, G.3
  • 55
    • 33747607029 scopus 로고    scopus 로고
    • Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria
    • Kinjo Y, Tupin E, Wu D, et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nat Immunol 2006; 7: 978-986.
    • (2006) Nat Immunol , vol.7 , pp. 978-986
    • Kinjo, Y.1    Tupin, E.2    Wu, D.3
  • 56
    • 0034069636 scopus 로고    scopus 로고
    • Atopic dermatitis: New insights and opportunities for therapeutic intervention
    • Leung DY. Atopic dermatitis: New insights and opportunities for therapeutic intervention. J Allergy Clin Immunol 2000; 105: 860-876.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 860-876
    • Leung, D.Y.1
  • 57
    • 0034748960 scopus 로고    scopus 로고
    • Bacterial infections and atopic dermatitis
    • Breuer K, Kapp A, Werfel T. Bacterial infections and atopic dermatitis. Allergy 2001; 56: 1034-1041.
    • (2001) Allergy , vol.56 , pp. 1034-1041
    • Breuer, K.1    Kapp, A.2    Werfel, T.3
  • 58
    • 0034532746 scopus 로고    scopus 로고
    • Comparative study of Staphylococcus aureus isolated from lesional and non-lesional skin of atopic dermatitis patients
    • Matsui K, Nishikawa A, Suto H, et al. Comparative study of Staphylococcus aureus isolated from lesional and non-lesional skin of atopic dermatitis patients. Microbiol Immunol 2000; 44: 945-947.
    • (2000) Microbiol Immunol , vol.44 , pp. 945-947
    • Matsui, K.1    Nishikawa, A.2    Suto, H.3
  • 59
    • 0034109633 scopus 로고    scopus 로고
    • Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB)
    • Breuer K, Wittmann M, Bösche B, et al. Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB). Allergy 2000; 55: 551-555.
    • (2000) Allergy , vol.55 , pp. 551-555
    • Breuer, K.1    Wittmann, M.2    Bösche, B.3
  • 60
    • 0027200566 scopus 로고
    • Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens
    • Leung DY, Harbeck R, Bina P, et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 1993; 92: 1374-1380.
    • (1993) J Clin Invest , vol.92 , pp. 1374-1380
    • Leung, D.Y.1    Harbeck, R.2    Bina, P.3
  • 61
    • 0034101969 scopus 로고    scopus 로고
    • Application of Staphylococcus enterotoxin B on normal and atopic skin induces up-regulation of T-cells by a superantigen-mediated mechanism
    • Skov L, Olsen JV, Giorno L, et al. Application of Staphylococcus enterotoxin B on normal and atopic skin induces up-regulation of T-cells by a superantigen-mediated mechanism,. J Allergy Clin Immunol 2000; 105: 820-826.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 820-826
    • Skov, L.1    Olsen, J.V.2    Giorno, L.3
  • 62
    • 0027370384 scopus 로고
    • Superantigens and their potential role in human disease
    • Kotzin BL, Leung DYM, Kappler J, et al. Superantigens and their potential role in human disease. Adv Immunol 1993; 54: 99-166.
    • (1993) Adv Immunol , vol.54 , pp. 99-166
    • Kotzin, B.L.1    Leung, D.Y.M.2    Kappler, J.3
  • 63
    • 0030820726 scopus 로고    scopus 로고
    • A peptide antibiotic from human skin
    • Harder J, Bartels J, Christophers E, et al. A peptide antibiotic from human skin. Nature 1997; 387: 861.
    • (1997) Nature , vol.387 , pp. 861
    • Harder, J.1    Bartels, J.2    Christophers, E.3
  • 64
    • 0032734313 scopus 로고    scopus 로고
    • Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium
    • O'Neill DA, Porter EM, Elewaut D, et al. Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium. J Immunol 1999; 163: 6718-6724.
    • (1999) J Immunol , vol.163 , pp. 6718-6724
    • O'Neill, D.A.1    Porter, E.M.2    Elewaut, D.3
  • 65
    • 0035190972 scopus 로고    scopus 로고
    • Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein
    • Birchler T, Seibl R, Büchner K, et al. Human Toll-like receptor 2 mediates induction of the antimicrobial peptide human beta-defensin 2 in response to bacterial lipoprotein. Eur J Immunol 2001; 31: 3131-3137.
    • (2001) Eur J Immunol , vol.31 , pp. 3131-3137
    • Birchler, T.1    Seibl, R.2    Büchner, K.3
  • 66
    • 1542721096 scopus 로고    scopus 로고
    • 753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype
    • 753Q polymorphism defines a subgroup of patients with atopic dermatitis having severe phenotype. J Allergy Clin Immunol 2004; 113: 565-567.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 565-567
    • Ahmad-Nejad, P.1    Mrabet-Dahbi, S.2    Breuer, K.3
  • 67
    • 42549101462 scopus 로고    scopus 로고
    • Dysregulation of toll-like receptor-2 (TLR-2)-induced effects in monocytes from patients with atopic dermatitis: Impact of the TLR-2 R753Q polymorphism
    • Niebuhr M, Langnickel J, Draing C et al. Dysregulation of toll-like receptor-2 (TLR-2)-induced effects in monocytes from patients with atopic dermatitis: Impact of the TLR-2 R753Q polymorphism. Allergy 2008; 63: 728-734.
    • (2008) Allergy , vol.63 , pp. 728-734
    • Niebuhr, M.1    Langnickel, J.2    Draing, C.3
  • 68
    • 0037668545 scopus 로고    scopus 로고
    • Pathogenesis of systemic lupus erythematosus
    • Mok CC, Lau CS. Pathogenesis of systemic lupus erythematosus. J Clin Pathol 2003; 56: 481-490.
    • (2003) J Clin Pathol , vol.56 , pp. 481-490
    • Mok, C.C.1    Lau, C.S.2
  • 70
    • 33750369226 scopus 로고    scopus 로고
    • Toll-like receptors in systemic autoimmune disease
    • Marshak-Rothstein A. Toll-like receptors in systemic autoimmune disease. Nat Rev Immunol 2006; 6: 823-835.
    • (2006) Nat Rev Immunol , vol.6 , pp. 823-835
    • Marshak-Rothstein, A.1
  • 71
    • 35748964708 scopus 로고    scopus 로고
    • Toll-like receptors 7, 8 and 9: Linking innate immunity to autoimmunity
    • Krieg AM, Vollmer J. Toll-like receptors 7, 8 and 9: Linking innate immunity to autoimmunity. Immunol Rev 2007; 220: 251-269.
    • (2007) Immunol Rev , vol.220 , pp. 251-269
    • Krieg, A.M.1    Vollmer, J.2
  • 72
    • 33947656512 scopus 로고    scopus 로고
    • Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors
    • Christensen SR, Shlomchik MJ. Regulation of lupus-related autoantibody production and clinical disease by Toll-like receptors. Semin Immunol 2007; 19: 11-23.
    • (2007) Semin Immunol , vol.19 , pp. 11-23
    • Christensen, S.R.1    Shlomchik, M.J.2
  • 73
    • 33745485521 scopus 로고    scopus 로고
    • Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus
    • Means TK, Luster AD. Toll-like receptor activation in the pathogenesis of systemic lupus erythematosus. Ann N Y Acad Sci 2005; 1062: 242-251.
    • (2005) Ann N Y Acad Sci , vol.1062 , pp. 242-251
    • Means, T.K.1    Luster, A.D.2
  • 74
    • 0025911863 scopus 로고
    • Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors
    • Ronnblom LE, Alm GV, Oberg KE. Autoimmunity after alpha-interferon therapy for malignant carcinoid tumors. Ann Intern Med 1990; 115: 178-183.
    • (1990) Ann Intern Med , vol.115 , pp. 178-183
    • Ronnblom, L.E.1    Alm, G.V.2    Oberg, K.E.3
  • 75
    • 0025057503 scopus 로고
    • Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour
    • Ronnblom LE, Alm GV, Oberg KE. Possible induction of systemic lupus erythematosus by interferon-alpha treatment in a patient with a malignant carcinoid tumour. J Intern Med 1990; 227: 207-210.
    • (1990) J Intern Med , vol.227 , pp. 207-210
    • Ronnblom, L.E.1    Alm, G.V.2    Oberg, K.E.3
  • 76
    • 0027511692 scopus 로고
    • Appearance of anti-DNA antibodies in patients treated with interferon-alpha
    • Ehrestein MR, McSweeney E, Sware M, et al. Appearance of anti-DNA antibodies in patients treated with interferon-alpha. Arthritis Rheum 1993; 36: 279-280.
    • (1993) Arthritis Rheum , vol.36 , pp. 279-280
    • Ehrestein, M.R.1    McSweeney, E.2    Sware, M.3
  • 77
    • 43349094856 scopus 로고    scopus 로고
    • Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    • Komatsuda A, Wakui H, Iwamoto M, et al. Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Exp Immunol 2008; 152: 482-487.
    • (2008) Clin Exp Immunol , vol.152 , pp. 482-487
    • Komatsuda, A.1    Wakui, H.2    Iwamoto, M.3
  • 78
    • 41549123222 scopus 로고    scopus 로고
    • Dysfunctional interferon-alpha production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus
    • Kwok SK, Lee JY, Park SH, et al. Dysfunctional interferon-alpha production by peripheral plasmacytoid dendritic cells upon Toll-like receptor-9 stimulation in patients with systemic lupus erythematosus. Arthritis Res Ther 2008; 10: R29.
    • (2008) Arthritis Res Ther , vol.10
    • Kwok, S.K.1    Lee, J.Y.2    Park, S.H.3
  • 79
    • 0034665534 scopus 로고    scopus 로고
    • 937 cells and lupus IgG is a potent IFN-alpha inducer
    • 937 cells and lupus IgG is a potent IFN-alpha inducer. J Immunol 2000; 165: 3519-3526.
    • (2000) J Immunol , vol.165 , pp. 3519-3526
    • Bave, U.1    Alm, G.V.2    Ronnblom, L.3
  • 80
    • 2642528779 scopus 로고    scopus 로고
    • Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG
    • Lovgren T, Eloranta ML, Bave U, et al. Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG. Arthritis Rheum 2004; 50: 1861-1872.
    • (2004) Arthritis Rheum , vol.50 , pp. 1861-1872
    • Lovgren, T.1    Eloranta, M.L.2    Bave, U.3
  • 81
    • 33847021499 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 2-9 agonists-induced cytokines and chemokines. I. Comparison with T cell receptor-induced responses
    • Ghosh TK, Mickelson DJ, Fink J, et al. Toll-like receptor (TLR) 2-9 agonists-induced cytokines and chemokines. I. Comparison with T cell receptor-induced responses. Cell Immunol 2006; 243: 48-57.
    • (2006) Cell Immunol , vol.243 , pp. 48-57
    • Ghosh, T.K.1    Mickelson, D.J.2    Fink, J.3
  • 82
    • 33746266273 scopus 로고    scopus 로고
    • 7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides
    • 7 and 8 to small molecule ligands with T-rich phosphorothiate oligodeoxynucleotides. Eur J Immunol 2006; 36: 1815-1826.
    • (2006) Eur J Immunol , vol.36 , pp. 1815-1826
    • Jurk, M.1    Kritzler, A.2    Schulte, B.3
  • 83
    • 33644530664 scopus 로고    scopus 로고
    • Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome
    • Gottenberg JE, Cagnard N, Lucchesi C. Activation of IFN pathways and plasmacytoid dendritic cell recruitment in target organs of primary Sjögren's syndrome. Proc Natl Acad Sci USA 2006; 103: 2770-2775.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2770-2775
    • Gottenberg, J.E.1    Cagnard, N.2    Lucchesi, C.3
  • 84
    • 45149116776 scopus 로고    scopus 로고
    • Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury
    • Yasuda H, Leelahavanichkul A, Tsunoda S, et al. Chloroquine and inhibition of Toll-like receptor 9 protect from sepsis-induced acute kidney injury. Am J Physiol Renal Physiol 2008; 294: F1050-F1058.
    • (2008) Am J Physiol Renal Physiol , vol.294
    • Yasuda, H.1    Leelahavanichkul, A.2    Tsunoda, S.3
  • 85
    • 38349088595 scopus 로고    scopus 로고
    • 7/9 antagonists as therapeutics for immune-mediated inflammatory disorders
    • 7/9 antagonists as therapeutics for immune-mediated inflammatory disorders. Inflamm Allergy Drug Targets 2007; 6: 223-235.
    • (2007) Inflamm Allergy Drug Targets , vol.6 , pp. 223-235
    • Sun, S.1    Rao, N.L.2    Venable, J.3
  • 86
    • 35648950010 scopus 로고    scopus 로고
    • New concepts in antimalarial use and mode of action in dermatology
    • Kalia S, Dutz JP. New concepts in antimalarial use and mode of action in dermatology. Dermatol Ther 2007; 20: 160-174.
    • (2007) Dermatol Ther , vol.20 , pp. 160-174
    • Kalia, S.1    Dutz, J.P.2
  • 87
    • 0025649409 scopus 로고
    • The role of microorganisms in psoriasis
    • Noah PW. The role of microorganisms in psoriasis. Semin Dermatol 1990; 9: 269.
    • (1990) Semin Dermatol , vol.9 , pp. 269
    • Noah, P.W.1
  • 88
    • 0038579508 scopus 로고    scopus 로고
    • Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: Modulation of TLR expression in chronic psoriasis
    • Baker BS, Ovigne JM, Powles AV, et al. Normal keratinocytes express Toll-like receptors (TLRs) 1, 2 and 5: Modulation of TLR expression in chronic psoriasis. Br J Dermatol 2003; 148: 670-679.
    • (2003) Br J Dermatol , vol.148 , pp. 670-679
    • Baker, B.S.1    Ovigne, J.M.2    Powles, A.V.3
  • 89
    • 0035872251 scopus 로고    scopus 로고
    • Bacterial heat shock protein-60 increases epithelial cell proliferation through the ERK1/2 MAP kinase
    • Zahng L, Pelech SL, Maurand D, et al. Bacterial heat shock protein-60 increases epithelial cell proliferation through the ERK1/2 MAP kinase. Exp Cell Res 2001; 266: 11.
    • (2001) Exp Cell Res , vol.266 , pp. 11
    • Zahng, L.1    Pelech, S.L.2    Maurand, D.3
  • 90
    • 0025247797 scopus 로고
    • Stress proteins and immunology
    • Young RA. Stress proteins and immunology. Annu Rev Immunol 1990; 8: 401.
    • (1990) Annu Rev Immunol , vol.8 , pp. 401
    • Young, R.A.1
  • 91
    • 0027492307 scopus 로고
    • Antibodies to mycobacterial 65-kDa heat shock protein and other immunodominant antigens in patients with psoriasis
    • Rambukkana A, Das PK, Wirkamp L, et al. Antibodies to mycobacterial 65-kDa heat shock protein and other immunodominant antigens in patients with psoriasis. J Invest Dermatol 1993; 100: 87.
    • (1993) J Invest Dermatol , vol.100 , pp. 87
    • Rambukkana, A.1    Das, P.K.2    Wirkamp, L.3
  • 94
    • 13444301384 scopus 로고    scopus 로고
    • Heat shock protein induced TCRγδ gene rearrangements in patients with oral cancer
    • Sadia P, Kafrawy AH, Miles DA, et al. Heat shock protein induced TCRγδ gene rearrangements in patients with oral cancer. Oral Oncol 2005; 41: 175.
    • (2005) Oral Oncol , vol.41 , pp. 175
    • Sadia, P.1    Kafrawy, A.H.2    Miles, D.A.3
  • 95
    • 36249024235 scopus 로고    scopus 로고
    • Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4, and T-cell receptor δ in plaque and guttate psoriasis
    • Seung NR, Park EJ, Kim CW, et al. Comparison of expression of heat-shock protein 60, Toll-like receptors 2 and 4, and T-cell receptor δ in plaque and guttate psoriasis. J Cutan Pathol 2007; 34: 903-911.
    • (2007) J Cutan Pathol , vol.34 , pp. 903-911
    • Seung, N.R.1    Park, E.J.2    Kim, C.W.3
  • 96
    • 66849140718 scopus 로고    scopus 로고
    • T cells respond to heat shock protein 60 via TLR2: Activation of adhesion and inhibition of chemokine receptors
    • Zanin-Zhorov A, Nussbaum G, Franitza S, et al. T cells respond to heat shock protein 60 via TLR2: Activation of adhesion and inhibition of chemokine receptors. FASEB J 2003; 127: 78.
    • (2003) FASEB J , vol.127 , pp. 78
    • Zanin-Zhorov, A.1    Nussbaum, G.2    Franitza, S.3
  • 98
    • 0033999986 scopus 로고    scopus 로고
    • Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin
    • Ting KM, Rothaupt D, McCormick TS et al. Overexpression of the oncofetal Fn variant containing the EDA splice-in segment in the dermal-epidermal junction of psoriatic uninvolved skin. J Invest Dermatol 2000; 114: 706-711.
    • (2000) J Invest Dermatol , vol.114 , pp. 706-711
    • Ting, K.M.1    Rothaupt, D.2    McCormick, T.S.3
  • 99
    • 32644438521 scopus 로고    scopus 로고
    • Innate and adaptive immunity and the pathophysiology of psoriasis
    • Gaspari AA. Innate and adaptive immunity and the pathophysiology of psoriasis. J Am Acad Dermatol 2006; 54 (Suppl. 2): S67-S80.
    • (2006) J Am Acad Dermatol , vol.54 , Issue.SUPPL. 2
    • Gaspari, A.A.1
  • 100
    • 10344256237 scopus 로고    scopus 로고
    • 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors
    • 7 agonist imiquimod in the presence of dermal plasmacytoid dendritic cell precursors. Arch Dermatol 2004; 104: 1490-1495.
    • (2004) Arch Dermatol , vol.104 , pp. 1490-1495
    • Gillet, M.1    Conrad, C.2    Geiges, M.3
  • 101
    • 1542317550 scopus 로고    scopus 로고
    • 7 mediated recognition of single-stranded RNA
    • 7 mediated recognition of single-stranded RNA. Science 2004; 303: 1529-1531.
    • (2004) Science , vol.303 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3
  • 102
    • 34948862264 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide
    • Lande R, Gregorio J, Facchinetti V, et al. Plasmacytoid dendritic cells sense self-DNA coupled with antimicrobial peptide. Nature 2007; 449: 564-569.
    • (2007) Nature , vol.449 , pp. 564-569
    • Lande, R.1    Gregorio, J.2    Facchinetti, V.3
  • 103
    • 66849143321 scopus 로고
    • Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10
    • Rivas JM, Ullrich SE. Systemic suppression of delayed-type hypersensitivity by supernatants from UV-irradiated keratinocytes. An essential role for keratinocyte-derived IL-10. J Immunol 1992; 76: 254-271.
    • (1992) J Immunol , vol.76 , pp. 254-271
    • Rivas, J.M.1    Ullrich, S.E.2
  • 104
    • 0026734326 scopus 로고
    • Tumor necrosis factor-alpha mediates ultraviolet light B-enhanced expression of contact hypersensitivity
    • Yoshikawa T, Kurimoto I, Streilein JW. Tumor necrosis factor-alpha mediates ultraviolet light B-enhanced expression of contact hypersensitivity. Immunology 1992; 76: 254-271.
    • (1992) Immunology , vol.76 , pp. 254-271
    • Yoshikawa, T.1    Kurimoto, I.2    Streilein, J.W.3
  • 106
    • 39049104004 scopus 로고    scopus 로고
    • Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis
    • Yusuf N, Nasti TH, Long JA, et al. Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis. Cancer Res 2008; 68: 615-622.
    • (2008) Cancer Res , vol.68 , pp. 615-622
    • Yusuf, N.1    Nasti, T.H.2    Long, J.A.3
  • 107
    • 37848999304 scopus 로고    scopus 로고
    • 7 and TLR8 as targets in cancer therapy
    • 7 and TLR8 as targets in cancer therapy. Oncogene 2008; 27: 190-199.
    • (2008) Oncogene , vol.27 , pp. 190-199
    • Schön, M.P.1    Schön, M.2
  • 109
    • 0043281537 scopus 로고    scopus 로고
    • 4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections
    • 4 confer hyporesponsiveness to lipopolysaccharide and interleukin-1 in a patient with recurrent bacterial infections. J Exp Med 2003; 198: 521-531.
    • (2003) J Exp Med , vol.198 , pp. 521-531
    • Medvedev, A.E.1    Lentschat, A.2    Kuhns, D.B.3
  • 110
    • 34948904198 scopus 로고    scopus 로고
    • 4 -deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity
    • 4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med 2007; 204: 2407-2422.
    • (2007) J Exp Med , vol.204 , pp. 2407-2422
    • Ku, C.L.1    Bernuth, H.2    Capucine, P.3
  • 111
    • 0036318851 scopus 로고    scopus 로고
    • Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments
    • Ahmad-Nejad P, Häcker H, Rutz R, et al. Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments. Eur J Immunol 2002; 32: 1958-1968.
    • (2002) Eur J Immunol , vol.32 , pp. 1958-1968
    • Ahmad-Nejad, P.1    Häcker, H.2    Rutz, R.3
  • 112
    • 40749098665 scopus 로고    scopus 로고
    • 93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
    • 93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 2008; 452: 234-238.
    • (2008) Nature , vol.452 , pp. 234-238
    • Kim, Y.M.1    Brinkmann, M.M.2    Paquet, M.E.3
  • 113
    • 9344251685 scopus 로고    scopus 로고
    • National seroprevalence and trends in herpes simplex virus type 1 in the United States, 1976-94
    • Schillinger JA, Xu F, Sternberg MR, et al. National seroprevalence and trends in herpes simplex virus type 1 in the United States, 1976-94. Sex Transm Dis 2004; 31: 753-760.
    • (2004) Sex Transm Dis , vol.31 , pp. 753-760
    • Schillinger, J.A.1    Xu, F.2    Sternberg, M.R.3
  • 115
    • 34548699323 scopus 로고    scopus 로고
    • 3 deficiency in patients with herpes simplex encephalitis
    • 3 deficiency in patients with herpes simplex encephalitis. Science 2007; 317: 1522-1527.
    • (2007) Science , vol.317 , pp. 1522-1527
    • Zhang, Y.S.1    Jouanguy, E.2    Ugoli, S.3
  • 118
    • 0034120295 scopus 로고    scopus 로고
    • Imiquimod, a topical immune response modifier induces migration of Langerhans cells
    • Suzuki H, Wang B, Shivhi GM, et al. Imiquimod, a topical immune response modifier induces migration of Langerhans cells. J Invest Dermatol 2000; 114: 135-141.
    • (2000) J Invest Dermatol , vol.114 , pp. 135-141
    • Suzuki, H.1    Wang, B.2    Shivhi, G.M.3
  • 119
    • 19744373211 scopus 로고    scopus 로고
    • Management of genital warts
    • Kodner CM, Nasraty S. Management of genital warts. Am Fam Physician 2004; 70: 2335-2342.
    • (2004) Am Fam Physician , vol.70 , pp. 2335-2342
    • Kodner, C.M.1    Nasraty, S.2
  • 120
    • 3342911554 scopus 로고    scopus 로고
    • Immune modulation and apoptosis induction: Two sides of the antitumoral activity of imiquimod
    • Schon MP, Schon M. Immune modulation and apoptosis induction: Two sides of the antitumoral activity of imiquimod. Apoptosis 2004; 9: 291-298.
    • (2004) Apoptosis , vol.9 , pp. 291-298
    • Schon, M.P.1    Schon, M.2
  • 121
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
    • Heil F, Hemmi H, Hochrein H, et al. Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8. Science 2004; 303: 1526-1529.
    • (2004) Science , vol.303 , pp. 1526-1529
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3
  • 122
    • 0036088492 scopus 로고    scopus 로고
    • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
    • Jurk M, Heil F, Vollmer J, et al. Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848. Nat Immunol 2002; 3: 499.
    • (2002) Nat Immunol , vol.3 , pp. 499
    • Jurk, M.1    Heil, F.2    Vollmer, J.3
  • 123
    • 33745521238 scopus 로고    scopus 로고
    • The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion
    • Schön MP, Schön M, Klotz KN. The small antitumoral immune response modifier imiquimod interacts with adenosine receptor signaling in a TLR7- and TLR8-independent fashion. J Invest Dermatol 2006; 126: 1338-1347.
    • (2006) J Invest Dermatol , vol.126 , pp. 1338-1347
    • Schön, M.P.1    Schön, M.2    Klotz, K.N.3
  • 124
    • 33645024337 scopus 로고    scopus 로고
    • Topical imiquimod treatment prevents UV-light induced loss of contact hypersensitivity and immune tolerance
    • Thatcher TH, Luzina I, Fishelevich R, et al. Topical imiquimod treatment prevents UV-light induced loss of contact hypersensitivity and immune tolerance. J Invest Dermatol 2006; 126: 821-831.
    • (2006) J Invest Dermatol , vol.126 , pp. 821-831
    • Thatcher, T.H.1    Luzina, I.2    Fishelevich, R.3
  • 125
    • 0242391997 scopus 로고    scopus 로고
    • The Toll-like receptor 7 (TLR7) specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily
    • Heil F, Ahmad-Nejad P, Hemmi H, et al. The Toll-like receptor 7 (TLR7) specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily. Eur J Immunol 2003; 3: 2987-2997.
    • (2003) Eur J Immunol , vol.3 , pp. 2987-2997
    • Heil, F.1    Ahmad-Nejad, P.2    Hemmi, H.3
  • 126
    • 0037460116 scopus 로고    scopus 로고
    • Recognition of pathogen-associated molecular patterns by TLR family
    • Akira S, Hemmi H. Recognition of pathogen-associated molecular patterns by TLR family. Immunol Lett 2003; 85: 85-95.
    • (2003) Immunol Lett , vol.85 , pp. 85-95
    • Akira, S.1    Hemmi, H.2
  • 127
    • 0029177444 scopus 로고
    • A new approach to vaccine adjuvants. Immunopotentiation by intracellular T-helper-like signals transmitted by loxoribine
    • Goodman MG. A new approach to vaccine adjuvants. Immunopotentiation by intracellular T-helper-like signals transmitted by loxoribine. Pharm Biotechnol 1995;6: 581-609.
    • (1995) Pharm Biotechnol , vol.6 , pp. 581-609
    • Goodman, M.G.1
  • 128
    • 0034351121 scopus 로고    scopus 로고
    • Phase 1, randomized, double-blind trial of 7-allyl-8-oxoguanosine (loxoribine) in advanced cancer
    • Agarwala SS, Kirkwood JM, Bryant J. Phase 1, randomized, double-blind trial of 7-allyl-8-oxoguanosine (loxoribine) in advanced cancer. Cytokines Cell Mol Ther 2000;6: 171-176.
    • (2000) Cytokines Cell Mol Ther , vol.6 , pp. 171-176
    • Agarwala, S.S.1    Kirkwood, J.M.2    Bryant, J.3
  • 129
    • 55249083982 scopus 로고    scopus 로고
    • Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma
    • Hofmann MA, Kors C, Audring H. Phase 1 evaluation of intralesionally injected TLR9-agonist PF-3512676 in patients with basal cell carcinoma or metastatic melanoma. J Immunother 2008;31: 520-527.
    • (2008) J Immunother , vol.31 , pp. 520-527
    • Hofmann, M.A.1    Kors, C.2    Audring, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.