Intracellular persistence of Borrelia burgdorferi in human synovial cells

Rheumatology International

Volumn 16, Issue 3, 1996, Pages 125-132

  Girschick, H J ^a   Huppertz, H I ^a   Russmann H ^a,b   Krenn, V ^a   Karch, H ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b STONY BROOK UNIVERSITY   (United States)

Author keywords

Borrelia burgdorferi; Intracellular persistence; Synovial cells

Indexed keywords

ANTIBIOTIC AGENT; CEFTRIAXONE;

ARTICLE; BACTERIUM ISOLATION; BORRELIA BURGDORFERI; BORRELIA INFECTION; CELL CULTURE; CELL MEMBRANE; CELL SURFACE; COMPARATIVE STUDY; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; CYTOSOL; HUMAN; HUMAN CELL; MACROPHAGE; PHAGOSOME; PRIORITY JOURNAL; SYNOVIOCYTE; TRANSMISSION ELECTRON MICROSCOPY;

EID: 0029840778     PISSN: 01728172     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF01409985     Document Type: Article

References (31)

1. Burgdorfer W, Barbour AG, Hayes SF, Benach JL, Grunwaldt E, Davis JP (1989) Lyme disease - a tick-home spirochetosis? Science 216: 1317-1319
2. Steere AC (1989) Lyme Disease. N Engl J Med 321: 586-596
3. Huppertz HI, Karch H, Suschke HJ, Döring E, Ganser G, Thon A, Bentas W (1995) Lyme arthritis in European children and adolescents. Arthritis Rheum 38: 361-368
4. Krause A, Brade V, Schoerner C, Solbach W, Kalden JR, Burmester GR (1991) T cell proliferation induced by Borrelia burgdorferi in patients with Lyme borreliosis. Arthritis Rheum 34: 393-402
5. Dressler F, Whalen JA, Reinhardt BN, Steere AC (1993) Western blotting in the sero diagnosis of Lyme arthritis. J Infect Dis 167:392-400
6. Szczepanski A, Benach JL (1991) Lyme borreliosis: host response to Borrelia burgdorferi. Microbiol Rev 55: 21-34
7. Georgilis K, Steere AC, Klempner MS (1991) Infectivity of Borrelia burgdorferi correlates with resistances to elimination by phagocytic cells. J Infect Dis 163: 150-155
8. Szczepanski A, Fleit HB (1988) Interaction between Borrelia burgdorferi and polymorphonuclear leukocytes-phagocytosis and the induction of the respiratory burst. Ann NY Acad Sci 539: 425-428
9. Rittig MG, Krause A, Hàupl T, Schaible UE, Modolell M, Kramer MD, Lutjen-Drecoll E, Simon MM, Burmester GR (1992) Coiling phagocytosis is the preferential phagocytic mechanism for Borrelia burgdorferi. Infect Immun 60: 4205-4212
10. Steere C, Duray PH, Butcher EC (1988) Spirochetal antigens and lymphoid cell surface markers in Lyme arthritis. Arthritis Rheum 31: 487-495
11. Nocton JJ, Dressler F, Rutledge BJ, Rys PN, Persing DH, Steere AC (1994) Detection of Borrelia burgdorferi DNA by polymerase chain reaction in synovial fluid from patients with Lyme arthritis. N Engl J Med 330: 229-234
12. Hulinska D, Jirous J, Valesova M, Herzogova J (1989) Ultrastructure of Borrelia burgdorferi in tissues of patients with Lyme disease. J Basic Microbiol 29: 73-83
13. Häupl T, Hahn G, Rittig M, Krause A, Schoerner Ch. Schönherr U, Kalden JR, Burmester GR (1993) Persistence of Borrelia burgdorferi in ligamentous tissue from a patient with chronic Lyme borreliosis. Arthritis Rheum 36: 1621-1626
14. Snydman DR, Schenkein DP, Beradi VP, Lastavica CC, Pariser KM (1986) Borrelia burgdorferi in joint fluid in chronic Lyme arthritis. Ann Intern Med 104: 798-800
15. Huppertz HI, Chantier JK (1991) Restricted mumps virus infection of cells derived from normal human joint tissue. J Gen Virol 72: 339-347
16. Huppertz HI (1994) How could infectious agents hide in synovial cells? Possible mechanisms of persistent viral infection in a model for the etiopathogenesis of chronic arthritis. Rheumatol Int 14:71-76
17. Radzun HJ, Kreipe H, Bödewadt S, Hansmann ML, Barth J, Parwaresch MR (1987) Ki-M 8 monoclonal antibody reactive with an intracytoplasmatic antigen of monocyte/macrophace lineage. Blood 69: 1320-1370
18. Papadopoulos Th, Ionescu L, Dämmrich J, Toomes H, Müller-Hennelink HK (1990) Type I and type II collagen promote adherence and spreading of type II pneumocytes in vitro. Lab Invest 62: 562-569
19. Huppertz HI, Karch H, Heeseman J (1995) Diagnostic value of synovial fluid analysis in children with reactive arthritis. Rheumatol Int 15: 167-170
20. Preac-Mursic V, Wilske B, Scherz G, Holmburger M, Suss E (1987) In vitro and in vivo susceptibility of Borrelia burgdorferi. Eur J Clin Microbiol 6: 424-426
21. Sigal LH (1992) Current recommendations tor the treatment of Lyme disease. Drugs 43: 683-699
22. Probst P, Reusser P, Fröscher R (1987) Synoviapenetration von Ceftriaxon in der othopädischen Chirurgie. Abstract no. 40, 15th International Congress of Chemotherapy, Istanbul
23. Ma Y, Sturrock A, Weiss JJ (1991) Intracellular localization of Borrelia burgdorferi within human endothelial cells. Infect Immun 59: 671-678
24. Comstock LE, Thomas DD (1989) Penetration of endothelial cell monolayers by Borrelia burgdorferi. Infect Immun 57: 1626-1628
25. Sadziene A, Barbour AG, Rosa PA, Thomas DD (1993) An Osp B mutant of Borrelia burgdorferi has reduced invasiveness in vitro and reduced infectivity in vivo. Infect Immun 61: 3590-3596
26. Georgilis K, Peacocke M, Klempner MS (1992) Fibroblasts protect the Lyme disease spirochete, Borrelia burgdorferi, front ceftriaxone in vitro. J Infect Dis 166: 440-444
27. Klempner MS, Noring R, Rogers RA (1993) Invasion of human skin fibroblasts by the Lyme disease spirochete. Borrelia burgdorferi. J Infect Dis 167: 1074-1081
28. Schmidli J, Hunziker T, Moesli P, Schaad UB (1988) Cultivation of Borrelia burgdorferi from joint fluid three months after treatment of facial palsy due to Lyme borreliosis. J Infect Dis 158: 905-906
29. Persing DH, Rutledge BJ, Rys PN, Podzorski DS, Mitchell PD, Reed KD, Liu B, Fikrig E, Malawista SE (1994) Target imbalance: disparity of Borrelia burgdorferi genetic material in synovial fluid from Lyme arthritis patients. J Infect Dis 169: 668-672
30. Karen H, Huppertz HI (1993) Repeated detection of Borrelia burgdorferi DNA in synovial fluid of a child with Lyme arthritis. Rheumatol Int 12: 227-230
31. Chary-Valckenaere I, Jaulhac B, Monteil H, Pourel J (1993) Diagnosis of Lyme disease. Current difficulties and prospects. Rev Rheum Engl Ed 62: 271-280