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Volumn 163, Issue 12, 1999, Pages 6718-6724

Expression and regulation of the human β-defensins hBD-1 and hBD-2 in intestinal epithelium

Author keywords

[No Author keywords available]

Indexed keywords

DEFENSIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 0032734313     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (578)

References (44)
  • 1
    • 0032005344 scopus 로고    scopus 로고
    • Antimicrobial Peptides of Vertebrates.
    • Ganz, T., and R. I. Lehrer. 1998. Antimicrobial peptides of vertebrates. Curr. Opin. Immunol. 10:41.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 41
    • Ganz, T.1    Lehrer, R.I.2
  • 2
    • 0029257519 scopus 로고
    • The subcellular localization of defensins and myeloperoxidase in human neutrophils: Immunocytochemical evidence for azurophil granule heterogeneity
    • Oren, A., and J. M. Taylor. 1995. The subcellular localization of defensins and myeloperoxidase in human neutrophils: immunocytochemical evidence for azurophil granule heterogeneity. J. Lab. Clin. Med. 125:340.
    • (1995) J. Lab. Clin. Med. , vol.125 , pp. 340
    • Oren, A.1    Taylor, J.M.2
  • 3
    • 0030914439 scopus 로고    scopus 로고
    • Localization of human intestinal defensin 5 in Paneth cell granules
    • Porter, E.M., L. Liu, A. Oren, P.A. Anton, and T. Ganz. 1997. Localization of human intestinal defensin 5 in Paneth cell granules. Infect. Immun. 65:2389.
    • (1997) Infect. Immun. , vol.65 , pp. 2389
    • Porter, E.M.1    Liu, L.2    Oren, A.3    Anton, P.A.4    Ganz, T.5
  • 4
    • 0030913746 scopus 로고    scopus 로고
    • Broad-spectrum antimicrobial activity of human intestinal defensin 5
    • Porter, E. M., E. van Dam, K. V. Valore, and T. Ganz. 1997. Broad-spectrum antimicrobial activity of human intestinal defensin 5. Infect. Immun. 65:2396.
    • (1997) Infect. Immun. , vol.65 , pp. 2396
    • Porter, E.M.1    Van Dam, E.2    Valore, K.V.3    Ganz, T.4
  • 6
    • 0031898688 scopus 로고    scopus 로고
    • Gene expression, immunolocalization and secretion of human defensin-5 in human female reproductive tract
    • Quayle, A. J., E. M. Porter, A. A. Nussbaum, Y. M. Wang, C. Brabec, K. P. Yip, and S. C. Mok. 1998. Gene expression, immunolocalization and secretion of human defensin-5 in human female reproductive tract. Am. J. Pathol. 152:1247.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1247
    • Quayle, A.J.1    Porter, E.M.2    Nussbaum, A.A.3    Wang, Y.M.4    Brabec, C.5    Yip, K.P.6    Mok, S.C.7
  • 9
    • 0030569343 scopus 로고    scopus 로고
    • Widespread expression of β-defensin hBD-1 in human secretory glands and epithelial cells
    • Zhao, C., I. Wang, and R. I. Lehrer. 1996. Widespread expression of β-defensin hBD-1 in human secretory glands and epithelial cells. FEBS Lett. 396:319.
    • (1996) FEBS Lett. , vol.396 , pp. 319
    • Zhao, C.1    Wang, I.2    Lehrer, R.I.3
  • 11
    • 0030949875 scopus 로고    scopus 로고
    • Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis
    • Goldman, M. J., G. M. Anderson, E. D. Stolzenberg, U. P Kari, M. Zasloff, and J. M. Wilson. 1997. Human β-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis. Cell 88:553.
    • (1997) Cell , vol.88 , pp. 553
    • Goldman, M.J.1    Anderson, G.M.2    Stolzenberg, E.D.3    Kari, U.P.4    Zasloff, M.5    Wilson, J.M.6
  • 14
    • 0031662487 scopus 로고    scopus 로고
    • Expression of the peptide antibiotic peptide human β-defensin 1 in cultured gingival epithelial cells and gingival tissue
    • Krisanaprakornkit, S., A. Weinberg, C. N. Perez, and B. A. Dale. 1998. Expression of the peptide antibiotic peptide human β-defensin 1 in cultured gingival epithelial cells and gingival tissue. Infect. Immun. 66:4222.
    • (1998) Infect. Immun. , vol.66 , pp. 4222
    • Krisanaprakornkit, S.1    Weinberg, A.2    Perez, C.N.3    Dale, B.A.4
  • 17
    • 0032548181 scopus 로고    scopus 로고
    • Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation
    • Liu, L., I. Wang, H. P. Jia, C. Zhao, H. H. Heng, B. C. Schutte, P. B. McCray, Jr., and T. Ganz. 1998. Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation. Gene 222:237.
    • (1998) Gene , vol.222 , pp. 237
    • Liu, L.1    Wang, I.2    Jia, H.P.3    Zhao, C.4    Heng, H.H.5    Schutte, B.C.6    McCray P.B., Jr.7    Ganz, T.8
  • 18
  • 20
    • 0029900207 scopus 로고    scopus 로고
    • Inducible expression of an antibiotic peptide gene in lipopolysaccharide challenged tracheal epithelial cells
    • Diamond, G., J. P. Russell, and C. L. Bevins. 1996. Inducible expression of an antibiotic peptide gene in lipopolysaccharide challenged tracheal epithelial cells. Proc. Natl. Acad. Sci. USA 93:5156.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5156
    • Diamond, G.1    Russell, J.P.2    Bevins, C.L.3
  • 21
    • 15644370080 scopus 로고    scopus 로고
    • Enteric β-defensin: Molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection
    • Tarver, A. P., D. P. Clark, G. Diamond, and C. L. Bevins. 1998. Enteric β-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection. Infect. Immun. 66:1045.
    • (1998) Infect. Immun. , vol.66 , pp. 1045
    • Tarver, A.P.1    Clark, D.P.2    Diamond, G.3    Bevins, C.L.4
  • 22
    • 0029877550 scopus 로고    scopus 로고
    • Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis α
    • Russell, J. P., G. Diamond, A. P. Tarver, T. F. Scanlin, and C. L. Bevins. 1998. Coordinate induction of two antibiotic genes in tracheal epithelial cells exposed to the inflammatory mediators lipopolysaccharide and tumor necrosis α. Infect. Immun. 64:1565.
    • (1998) Infect. Immun. , vol.64 , pp. 1565
    • Russell, J.P.1    Diamond, G.2    Tarver, A.P.3    Scanlin, T.F.4    Bevins, C.L.5
  • 23
    • 0028902757 scopus 로고
    • Epithelial antibiotics induced at sites of inflammation
    • Schonwetter, B. S., E. D. Stolzenberg, and M. A. Zasloff. 1995. Epithelial antibiotics induced at sites of inflammation. Science 267:1645.
    • (1995) Science , vol.267 , pp. 1645
    • Schonwetter, B.S.1    Stolzenberg, E.D.2    Zasloff, M.A.3
  • 24
    • 0032898451 scopus 로고    scopus 로고
    • A novel mouse β-defensin, DefB2, which is upregulated in the airways by lipopolysaccharide
    • Morrison, G. M., D. J. Davidson, and J. R. Dorin. 1999. A novel mouse β-defensin, DefB2, which is upregulated in the airways by lipopolysaccharide. FEBS Lett. 442:112.
    • (1999) FEBS Lett. , vol.442 , pp. 112
    • Morrison, G.M.1    Davidson, D.J.2    Dorin, J.R.3
  • 25
    • 0033043785 scopus 로고    scopus 로고
    • Mouse β-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs
    • Bals, R., X. Wang, R.L. Meegalla, D. J. Weiner, M. C. Nehls, and J. M. Wilson. 1999. Mouse β-defensin 3 is an inducible antimicrobial peptide expressed in the epithelia of multiple organs. Infect. Immun. 67:3542.
    • (1999) Infect. Immun. , vol.67 , pp. 3542
    • Bals, R.1    Wang, X.2    Meegalla, R.L.3    Weiner, D.J.4    Nehls, M.C.5    Wilson, J.M.6
  • 26
    • 0027146545 scopus 로고
    • Differential cytokine expression by human intestinal epithelial cell lines: Regulated expression of interleukin-8
    • Eckmann, L., H. C. Jung, C. Schurer-Maly, A. Panja, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1995. Differential cytokine expression by human intestinal epithelial cell lines: regulated expression of interleukin-8. Gastroenterology 105: 1689.
    • (1995) Gastroenterology , vol.105 , pp. 1689
    • Eckmann, L.1    Jung, H.C.2    Schurer-Maly, C.3    Panja, A.4    Morzycka-Wroblewska, E.5    Kagnoff, M.F.6
  • 27
    • 0027486788 scopus 로고    scopus 로고
    • Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry
    • Eckmann, L., M. F. Kagnoff, and J. Fierer. 1998. Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry. Infect. Immun. 61:4569.
    • (1998) Infect. Immun. , vol.61 , pp. 4569
    • Eckmann, L.1    Kagnoff, M.F.2    Fierer, J.3
  • 29
    • 0030017256 scopus 로고    scopus 로고
    • Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intracellular adhesion molecule-1 (ICAM-I)
    • Huang, G. T., L. Eckmann, T. C. Savidge, and M. F. Kagnoff. 1996. Infection of human intestinal epithelial cells with invasive bacteria upregulates apical intracellular adhesion molecule-1 (ICAM-I). J. Clin. Invest. 98:572.
    • (1996) J. Clin. Invest. , vol.98 , pp. 572
    • Huang, G.T.1    Eckmann, L.2    Savidge, T.C.3    Kagnoff, M.F.4
  • 30
    • 0028864991 scopus 로고
    • A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion
    • Jung, H. C., L. Eckmann, A. Panja, J. Fierer, E. Morzycka-Wroblewska, and M. F. Kagnoff. 1995. A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion. J. Clin. Invest. 95:55.
    • (1995) J. Clin. Invest. , vol.95 , pp. 55
    • Jung, H.C.1    Eckmann, L.2    Panja, A.3    Fierer, J.4    Morzycka-Wroblewska, E.5    Kagnoff, M.F.6
  • 31
    • 0030831109 scopus 로고    scopus 로고
    • Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines
    • Laurent, F., L. Eckmann, T. C. Savidge, G. Morgan, C. Theodus, M. Naciri, and M. F. Kagnoff. 1997. Cryptosporidium parvum infection of human intestinal epithelial cells induces the polarized secretion of C-X-C chemokines. Infect. Immun. 65:5067.
    • (1997) Infect. Immun. , vol.65 , pp. 5067
    • Laurent, F.1    Eckmann, L.2    Savidge, T.C.3    Morgan, G.4    Theodus, C.5    Naciri, M.6    Kagnoff, M.F.7
  • 33
    • 0029881475 scopus 로고    scopus 로고
    • Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers
    • Salzman, A., A. G. Denenberg, I. Ueta, M. O'Connor, S. C. Linn, and C. Szabo. 1996. Induction and activity of nitric oxide synthase in cultured human intestinal epithelial monolayers. Am. J. Physiol. 270:G565.
    • (1996) Am. J. Physiol. , vol.270
    • Salzman, A.1    Denenberg, A.G.2    Ueta, I.3    O'Connor, M.4    Linn, S.C.5    Szabo, C.6
  • 34
    • 0031656002 scopus 로고    scopus 로고
    • Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells
    • Witthoft, T. L., L. Eckmann, J. M. Kim, and M. F. Kagnoff. 1998. Enteroinvasive bacteria directly activate expression of iNOS and NO production in human colon epithelial cells. Am. J. Physiol. 275:G564.
    • (1998) Am. J. Physiol. , vol.275
    • Witthoft, T.L.1    Eckmann, L.2    Kim, J.M.3    Kagnoff, M.F.4
  • 35
    • 0030870251 scopus 로고    scopus 로고
    • Differential and regulated expression of C-X-C, C-C and C-chemokines by human colon epithelial cells
    • Yang, S. K., L. Eckmann, A. Panja, and M. F. Kagnoff. 1997. Differential and regulated expression of C-X-C, C-C and C-chemokines by human colon epithelial cells. Gastroenterology 113:1214.
    • (1997) Gastroenterology , vol.113 , pp. 1214
    • Yang, S.K.1    Eckmann, L.2    Panja, A.3    Kagnoff, M.F.4
  • 36
    • 0033178735 scopus 로고    scopus 로고
    • Nuclear factor-κB is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria
    • Elewaut, D. J. DiDonato, J. M. Kim, F. Truong, L. Eckmann, and M. F. Kagnoff. 1999. Nuclear factor-κB is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteria. J. Immunol. 163:1457.
    • (1999) J. Immunol. , vol.163 , pp. 1457
    • Elewaut1    DiDonato, D.J.2    Kim, J.M.3    Truong, F.4    Eckmann, L.5    Kagnoff, M.F.6
  • 38
    • 0031949436 scopus 로고    scopus 로고
    • Cryptosporidium parvum infection of human intestinal xenografts in SCID mice induces production of human tumor necrosis factor a and interleukin-8
    • Seydel, K. B., T. Zhang, G. A. Champion, C. Fichtenbaum, P. E. Swanson, S. Tzipori, J. K. Griffiths, and S. L. Stanley. 1998. Cryptosporidium parvum infection of human intestinal xenografts in SCID mice induces production of human tumor necrosis factor a and interleukin-8. Infect. Immun. 66:2379.
    • (1998) Infect. Immun. , vol.66 , pp. 2379
    • Seydel, K.B.1    Zhang, T.2    Champion, G.A.3    Fichtenbaum, C.4    Swanson, P.E.5    Tzipori, S.6    Griffiths, J.K.7    Stanley, S.L.8
  • 39
    • 0031932422 scopus 로고    scopus 로고
    • Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor κB super-repressor in human intestinal epithelial cells
    • Jobin, C., A. Panja, C. Hellerbrand, Y. Limuro, J. Didonato, D. A. Brenner, and R. B. Sartor. 1998. Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor κB super-repressor in human intestinal epithelial cells. J. Immunol. 160:410.
    • (1998) J. Immunol. , vol.160 , pp. 410
    • Jobin, C.1    Panja, A.2    Hellerbrand, C.3    Limuro, Y.4    Didonato, J.5    Brenner, D.A.6    Sartor, R.B.7
  • 40
    • 0033561628 scopus 로고    scopus 로고
    • TNF receptor-associated factor-2 is involved in both IL-1 β and TNF-α signaling cascades leading to NF-κB activation and IL-8 expression in human intestinal epithelial cells
    • Jobin, C. A., L. Holt, C. A. Bradham, K. Streetz, D. A. Brenner, and R. B. Sartor. 1999. TNF receptor-associated factor-2 is involved in both IL-1 β and TNF-α signaling cascades leading to NF-κB activation and IL-8 expression in human intestinal epithelial cells. J. Immunol. 162:4447.
    • (1999) J. Immunol. , vol.162 , pp. 4447
    • Jobin, C.A.1    Holt, L.2    Bradham, C.A.3    Streetz, K.4    Brenner, D.A.5    Sartor, R.B.6
  • 41
    • 0030747618 scopus 로고    scopus 로고
    • The mouse genome encodes a single homolog of the antimicrobial human peptide β-defensin 1
    • Huttner, K. M., C. A. Kozak, and C. L. Bevins. The mouse genome encodes a single homolog of the antimicrobial human peptide β-defensin 1. FEBS Lett. 413:45.
    • FEBS Lett. , vol.413 , pp. 45
    • Huttner, K.M.1    Kozak, C.A.2    Bevins, C.L.3
  • 43
    • 0032482980 scopus 로고    scopus 로고
    • The peptide antibiotic LL37/hCAP18 is expressed in epithelia of the human lung where it has broad-spectrum antimicrobial activity at the airway surface
    • Bals, R., X. Wang, M. Zasloff, and J. M. Wilson. 1998. The peptide antibiotic LL37/hCAP18 is expressed in epithelia of the human lung where it has broad-spectrum antimicrobial activity at the airway surface. Proc. Natl. Acad Sci. USA 95:9541.
    • (1998) Proc. Natl. Acad Sci. USA , vol.95 , pp. 9541
    • Bals, R.1    Wang, X.2    Zasloff, M.3    Wilson, J.M.4
  • 44
    • 0033560645 scopus 로고    scopus 로고
    • Transfer of cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model
    • Bals, R., D. J. Weiner, R. L. Meegalla, and J. M. Watson. 1999. Transfer of cathelicidin peptide antibiotic gene restores bacterial killing in a cystic fibrosis xenograft model. J. Clin. Invest. 103:1113.
    • (1999) J. Clin. Invest. , vol.103 , pp. 1113
    • Bals, R.1    Weiner, D.J.2    Meegalla, R.L.3    Watson, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.