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Volumn 9, Issue 1, 2009, Pages 40-55

Neurotrophic factor treatment after spinal root avulsion injury

Author keywords

Avulsion; Brachial plexus injury; Nerve implantation; Neurotrophic factors; Peripheral nerve injury

Indexed keywords

ARTEMIN; BRAIN DERIVED NEUROTROPHIC FACTOR; CARDIOTROPHIN 1; CILIARY NEUROTROPHIC FACTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR 2; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; LENTIVIRUS VECTOR; LEUKEMIA INHIBITORY FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN; NEUROTROPHIN 3; NEUROTROPHIN 4; NEUROTROPHIN 6; NEURTURIN; PERSEPHIN; PLEIOTROPHIN; RILUZOLE; SCATTER FACTOR; SERINE PROTEINASE INHIBITOR; SOMATOMEDIN; SOMATOMEDIN B; SOMATOMEDIN C; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA3; VASCULOTROPIN;

EID: 62549107119     PISSN: 18715249     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152409787601914     Document Type: Review
Times cited : (26)

References (242)
  • 1
    • 0028269017 scopus 로고
    • Ventral root avulsion: An experimental model of death of adult motor neurons
    • Koliatsos V. E.; Price W. L.; Pardo C. A.; Price D. L. Ventral root avulsion: an experimental model of death of adult motor neurons. J. Comp. Neurol., 1994, 342(1), 35-44.
    • (1994) J. Comp. Neurol , vol.342 , Issue.1 , pp. 35-44
    • Koliatsos, V.E.1    Price, W.L.2    Pardo, C.A.3    Price, D.L.4
  • 2
    • 0027154946 scopus 로고
    • Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry
    • Wu W. Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry. Exp. Neurol., 1993, 720(2), 153-159.
    • (1993) Exp. Neurol , vol.720 , Issue.2 , pp. 153-159
    • Wu, W.1
  • 3
    • 0028872012 scopus 로고
    • Return of function after spinal cord implantation of avulsed spinal nerve roots
    • Carlstedt T.; Grane P.; Hallin R. G.; Noren G. Return of function after spinal cord implantation of avulsed spinal nerve roots. Lancet, 1995, 346(8986), 1323-1325.
    • (1995) Lancet , vol.346 , Issue.8986 , pp. 1323-1325
    • Carlstedt, T.1    Grane, P.2    Hallin, R.G.3    Noren, G.4
  • 4
    • 0027987963 scopus 로고
    • Implantation of PNS graft inhibits the induction of neuronal nitric oxide synthase and enhances the survival of spinal motoneurons following root avulsion
    • Wu W.; Han K.; Li L.; Schinco F. P. Implantation of PNS graft inhibits the induction of neuronal nitric oxide synthase and enhances the survival of spinal motoneurons following root avulsion. Exp. Neurol., 1994, 129(2), 335-339.
    • (1994) Exp. Neurol , vol.129 , Issue.2 , pp. 335-339
    • Wu, W.1    Han, K.2    Li, L.3    Schinco, F.P.4
  • 5
    • 0034589620 scopus 로고    scopus 로고
    • Spinal cord motoneuron maintenance, injury and repair
    • Carlstedt T.; Cullheim S. Spinal cord motoneuron maintenance, injury and repair. Prog. Brain Res., 2000, 127501-514.
    • (2000) Prog. Brain Res , vol.127 , pp. 501-514
    • Carlstedt, T.1    Cullheim, S.2
  • 6
    • 0034433905 scopus 로고    scopus 로고
    • Spinal nerve root repair and reimplantation of avulsed ventral roots into the spinal cord after brachial plexus injury
    • Carlstedt T.; Anand P.; Hallin R.; Misra P. V.; Noren G.; Seferlis T. Spinal nerve root repair and reimplantation of avulsed ventral roots into the spinal cord after brachial plexus injury. J. Neurosurg., 2000, 93(2 Suppl), 237-247.
    • (2000) J. Neurosurg , vol.93 , Issue.2 SUPPL. , pp. 237-247
    • Carlstedt, T.1    Anand, P.2    Hallin, R.3    Misra, P.V.4    Noren, G.5    Seferlis, T.6
  • 7
    • 0036825081 scopus 로고    scopus 로고
    • Properties of motoneurons underlying their regenerative capacity after axon lesions in the ventral funiculus or at the surface of the spinal cord
    • Cullheim S.; Wallquist W.; Hammarberg H.; Linda H.; Piehl F.; Carlstedt T.; Risling M. Properties of motoneurons underlying their regenerative capacity after axon lesions in the ventral funiculus or at the surface of the spinal cord. Brain Res. Brain Res. Rev., 2002, 40(1-3), 309-316.
    • (2002) Brain Res. Brain Res. Rev , vol.40 , Issue.1-3 , pp. 309-316
    • Cullheim, S.1    Wallquist, W.2    Hammarberg, H.3    Linda, H.4    Piehl, F.5    Carlstedt, T.6    Risling, M.7
  • 8
    • 0021863787 scopus 로고
    • The treatment of brachial plexus injuries. 7nt
    • Narakas A. O. The treatment of brachial plexus injuries. 7nt. Orthop., 1985, 9(1), 29-36.
    • (1985) Orthop , vol.9 , Issue.1 , pp. 29-36
    • Narakas, A.O.1
  • 10
    • 0038024459 scopus 로고    scopus 로고
    • Obstetrical brachial plexus palsy
    • Dunham E. A. Obstetrical brachial plexus palsy. Orthop. Nurs., 2003, 22(2), 106-116.
    • (2003) Orthop. Nurs , vol.22 , Issue.2 , pp. 106-116
    • Dunham, E.A.1
  • 11
    • 0030914055 scopus 로고    scopus 로고
    • Epidemiology of brachial plexus injuries in a multi-trauma population
    • Midha R. Epidemiology of brachial plexus injuries in a multi-trauma population. Neurosurgery, 1997, 40(6), 1182-1188.
    • (1997) Neurosurgery , vol.40 , Issue.6 , pp. 1182-1188
    • Midha, R.1
  • 12
    • 0034529904 scopus 로고    scopus 로고
    • Approaches permitting and enhancing motoneuron regeneration after spinal cord, ventral root, plexus and peripheral nerve injuries
    • Carlstedt T. Approaches permitting and enhancing motoneuron regeneration after spinal cord, ventral root, plexus and peripheral nerve injuries. Curr. Opin. Neurol., 2000, 13(6), 683-686.
    • (2000) Curr. Opin. Neurol , vol.13 , Issue.6 , pp. 683-686
    • Carlstedt, T.1
  • 13
    • 4544314428 scopus 로고    scopus 로고
    • Nerve transfers for severe brachial plexus injuries: A review
    • Midha R. Nerve transfers for severe brachial plexus injuries: a review. Neurosurg. Focus., 2004, 16(5), E5.
    • (2004) Neurosurg. Focus , vol.16 , Issue.5
    • Midha, R.1
  • 14
    • 0034066864 scopus 로고    scopus 로고
    • Restoration of prehension with the double free muscle technique following complete avulsion of the brachial plexus. Indications and long-term results
    • Doi K.; Muramatsu K.; Hattori Y.; Otsuka K.; Tan S. H.; Nanda V.; Watanabe M. Restoration of prehension with the double free muscle technique following complete avulsion of the brachial plexus. Indications and long-term results. J. Bone Joint Surg. Am., 2000, 82(5), 652-666.
    • (2000) J. Bone Joint Surg. Am , vol.82 , Issue.5 , pp. 652-666
    • Doi, K.1    Muramatsu, K.2    Hattori, Y.3    Otsuka, K.4    Tan, S.H.5    Nanda, V.6    Watanabe, M.7
  • 16
    • 0024374643 scopus 로고
    • Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat
    • Cullheim S.; Carlstedt T.; Linda H.; Risling M.; Ulfhake B. Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat. Neuroscience, 1989, 29(3), 725-733.
    • (1989) Neuroscience , vol.29 , Issue.3 , pp. 725-733
    • Cullheim, S.1    Carlstedt, T.2    Linda, H.3    Risling, M.4    Ulfhake, B.5
  • 17
    • 0027471548 scopus 로고
    • Functional recovery after ventral root avulsion and implantation in the spinal cord
    • Carlstedt T. Functional recovery after ventral root avulsion and implantation in the spinal cord. Clin. Neurol. Neurosurg., 1993, 95 (Suppl), S109-S111.
    • (1993) Clin. Neurol. Neurosurg , vol.95 , Issue.SUPPL.
    • Carlstedt, T.1
  • 18
    • 0022981406 scopus 로고
    • Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat
    • Carlstedt T.; Linda H.; Cullheim S.; Risling M. Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat. Acta Physiol. Scand., 1986, 128(4), 645-646.
    • (1986) Acta Physiol. Scand , vol.128 , Issue.4 , pp. 645-646
    • Carlstedt, T.1    Linda, H.2    Cullheim, S.3    Risling, M.4
  • 19
    • 0038278751 scopus 로고    scopus 로고
    • Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements
    • Bertelli J. A.; Ghizoni M. F. Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements. Neurosurgery, 2003, 52(6), 1385-1389.
    • (2003) Neurosurgery , vol.52 , Issue.6 , pp. 1385-1389
    • Bertelli, J.A.1    Ghizoni, M.F.2
  • 21
    • 4544365337 scopus 로고    scopus 로고
    • Restoration of hand function and so called "breathing arm" after intraspinal repair of C5-T1 brachial plexus avulsion injury. Case report
    • Carlstedt T.; Anand P.; Htut M.; Misra P.; Svensson M. Restoration of hand function and so called "breathing arm" after intraspinal repair of C5-T1 brachial plexus avulsion injury. Case report. Neurosurg. Focus., 2004, 16(5), E7.
    • (2004) Neurosurg. Focus , vol.16 , Issue.5
    • Carlstedt, T.1    Anand, P.2    Htut, M.3    Misra, P.4    Svensson, M.5
  • 22
    • 0033916994 scopus 로고    scopus 로고
    • An improved method for avulsion of lumbar nerve roots as an experimental model of nitric oxide-mediated neuronal degeneration
    • He J. W.; Hirata K.; Kuraoka A.; Kawabuchi M. An improved method for avulsion of lumbar nerve roots as an experimental model of nitric oxide-mediated neuronal degeneration. Brain Res. Brain Res. Protoc., 2000, 5(3), 223-230.
    • (2000) Brain Res. Brain Res. Protoc , vol.5 , Issue.3 , pp. 223-230
    • He, J.W.1    Hirata, K.2    Kuraoka, A.3    Kawabuchi, M.4
  • 23
    • 33644817653 scopus 로고    scopus 로고
    • Peripheral nerve avulsion injuries as experimental models for adult motoneuron degeneration
    • Watabe K.; Hayashi Y.; Kawazoe Y. Peripheral nerve avulsion injuries as experimental models for adult motoneuron degeneration. Neuropathology, 2005, 25(4), 371-380.
    • (2005) Neuropathology , vol.25 , Issue.4 , pp. 371-380
    • Watabe, K.1    Hayashi, Y.2    Kawazoe, Y.3
  • 24
    • 0032864716 scopus 로고    scopus 로고
    • Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis
    • Martin L. J.; Kaiser A.; Price A. C. Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis. J. Neurobiol., 1999, 40(2), 185-201.
    • (1999) J. Neurobiol , vol.40 , Issue.2 , pp. 185-201
    • Martin, L.J.1    Kaiser, A.2    Price, A.C.3
  • 25
    • 0016758938 scopus 로고
    • The perineuronal glial reaction after axotomy
    • Torvik A.; Soreide A. J. The perineuronal glial reaction after axotomy. Brain Res., 1975, 95(2-3), 519-529.
    • (1975) Brain Res , vol.95 , Issue.2-3 , pp. 519-529
    • Torvik, A.1    Soreide, A.J.2
  • 26
    • 0028825290 scopus 로고
    • The role of nitric oxide in facial motoneuronal death
    • Ruan R. S.; Leong S. K.; Yeoh K. H. The role of nitric oxide in facial motoneuronal death. Brain Res., 1995, 698(1-2), 163-168.
    • (1995) Brain Res , vol.698 , Issue.1-2 , pp. 163-168
    • Ruan, R.S.1    Leong, S.K.2    Yeoh, K.H.3
  • 27
    • 0030989953 scopus 로고    scopus 로고
    • Regulation of nitric oxide synthase expression in motoneurons following nerve injury
    • Yu W. H. Regulation of nitric oxide synthase expression in motoneurons following nerve injury. Dev. Neurosci., 1997, 19(3), 247-254.
    • (1997) Dev. Neurosci , vol.19 , Issue.3 , pp. 247-254
    • Yu, W.H.1
  • 28
    • 21844470751 scopus 로고    scopus 로고
    • Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation
    • Martin L. J.; Chen K.; Liu Z. Adult motor neuron apoptosis is mediated by nitric oxide and Fas death receptor linked by DNA damage and p53 activation. J. Neurosci., 2005, 25(27), 6449-6459.
    • (2005) J. Neurosci , vol.25 , Issue.27 , pp. 6449-6459
    • Martin, L.J.1    Chen, K.2    Liu, Z.3
  • 29
    • 0022981406 scopus 로고
    • Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat
    • Carlstedt T.; Linda H.; Cullheim S.; Risling M. Reinnervation of hind limb muscles after ventral root avulsion and implantation in the lumbar spinal cord of the adult rat. Acta Physiol. Scand., 1986, 128(4), 645-646.
    • (1986) Acta Physiol. Scand , vol.128 , Issue.4 , pp. 645-646
    • Carlstedt, T.1    Linda, H.2    Cullheim, S.3    Risling, M.4
  • 30
    • 62549134646 scopus 로고    scopus 로고
    • Spinal root avulsion and repair model
    • Chen, J, Xu, X.M, Xu, Z.C, Zhang, J, Ed, Chapter 42, Humana Press
    • Chu, T. H.; Wu, W. Spinal root avulsion and repair model. In animal models of acute neurological injuries. Chen, J.; Xu, X.M.; Xu, Z.C.; Zhang, J., Ed., Chapter 42, Humana Press. 2008.
    • (2008) In animal models of acute neurological injuries
    • Chu, T.H.1    Wu, W.2
  • 31
    • 0032578036 scopus 로고    scopus 로고
    • Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice
    • Li L.; Houenou L. J.; Wu W.; Lei M.; Prevette D. M.; Oppenheim R. W. Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice. J. Comp. Neurol., 1998, 396(2), 158-168.
    • (1998) J. Comp. Neurol , vol.396 , Issue.2 , pp. 158-168
    • Li, L.1    Houenou, L.J.2    Wu, W.3    Lei, M.4    Prevette, D.M.5    Oppenheim, R.W.6
  • 32
    • 0032864716 scopus 로고    scopus 로고
    • Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis. J
    • Martin L. J.; Kaiser A.; Price A. C. Motor neuron degeneration after sciatic nerve avulsion in adult rat evolves with oxidative stress and is apoptosis. J. Neurobiol., 1999, 40(2), 185-201.
    • (1999) Neurobiol , vol.40 , Issue.2 , pp. 185-201
    • Martin, L.J.1    Kaiser, A.2    Price, A.C.3
  • 33
    • 34548701773 scopus 로고    scopus 로고
    • Bax-dependent and -independent death of motoneurons after facial nerve injury in adult mice
    • Park O. H.; Lee K. J.; Rhyu I. J.; Geum D.; Kim H.; Buss R.; Oppenheim R. W.; Sun W. Bax-dependent and -independent death of motoneurons after facial nerve injury in adult mice. Eur. J. Neurosci., 2007, 26(6), 1421-1432.
    • (2007) Eur. J. Neurosci , vol.26 , Issue.6 , pp. 1421-1432
    • Park, O.H.1    Lee, K.J.2    Rhyu, I.J.3    Geum, D.4    Kim, H.5    Buss, R.6    Oppenheim, R.W.7    Sun, W.8
  • 34
    • 70350323571 scopus 로고    scopus 로고
    • Response of nitric oxide synthase to neuronal injury
    • Wu W. Response of nitric oxide synthase to neuronal injury. Handbook of Chemical Neuroanatomy, 2000, 17(LX), 315-353.
    • (2000) Handbook of Chemical Neuroanatomy , vol.17 , Issue.LX , pp. 315-353
    • Wu, W.1
  • 35
    • 31344482594 scopus 로고    scopus 로고
    • Complement activation after lumbosacral ventral root avulsion injury
    • Ohlsson M.; Havton L. A. Complement activation after lumbosacral ventral root avulsion injury. Neurosci. Lett., 2006, 394(3), 179-183.
    • (2006) Neurosci. Lett , vol.394 , Issue.3 , pp. 179-183
    • Ohlsson, M.1    Havton, L.A.2
  • 36
    • 2342614777 scopus 로고    scopus 로고
    • Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion
    • Gu H. Y.; Chai H.; Zhang J. Y.; Yao Z. B.; Zhou L. H.; Wong W. M.; Bruce I.; Wu W. T. Survival, regeneration and functional recovery of motoneurons in adult rats by reimplantation of ventral root following spinal root avulsion. Eur. J. Neurosci., 2004, 19(8), 2123-2131.
    • (2004) Eur. J. Neurosci , vol.19 , Issue.8 , pp. 2123-2131
    • Gu, H.Y.1    Chai, H.2    Zhang, J.Y.3    Yao, Z.B.4    Zhou, L.H.5    Wong, W.M.6    Bruce, I.7    Wu, W.T.8
  • 37
    • 0026590698 scopus 로고
    • A light and electron microscopic study of intracellularly HRP-labeled lumbar motoneurons after intramedullary axotomy in the adult cat
    • Linda H.; Cullheim S.; Risling M. A light and electron microscopic study of intracellularly HRP-labeled lumbar motoneurons after intramedullary axotomy in the adult cat. J. Comp. Neurol., 1992, 318(2), 188-208.
    • (1992) J. Comp. Neurol , vol.318 , Issue.2 , pp. 188-208
    • Linda, H.1    Cullheim, S.2    Risling, M.3
  • 38
    • 0034638245 scopus 로고    scopus 로고
    • Ultrastructural evidence for a preferential elimination of glutamate-immunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy
    • Linda H.; Shupliakov O.; Ornung G.; Ottersen O. P.; Storm-Mathisen J.; Risling M.; Cullheim S. Ultrastructural evidence for a preferential elimination of glutamate-immunoreactive synaptic terminals from spinal motoneurons after intramedullary axotomy. J. Comp. Neurol., 2000, 425(1), 10-23.
    • (2000) J. Comp. Neurol , vol.425 , Issue.1 , pp. 10-23
    • Linda, H.1    Shupliakov, O.2    Ornung, G.3    Ottersen, O.P.4    Storm-Mathisen, J.5    Risling, M.6    Cullheim, S.7
  • 39
    • 0036428639 scopus 로고    scopus 로고
    • Microarray analysis suggests the involvement of proteasomes, lysosomes, and matrix metalloproteinases in the response of motor neurons to root avulsion
    • Hu J.; Fink D.; Mata M. Microarray analysis suggests the involvement of proteasomes, lysosomes, and matrix metalloproteinases in the response of motor neurons to root avulsion. Eur. J. Neurosci., 2002, 16(8), 1409-1416.
    • (2002) Eur. J. Neurosci , vol.16 , Issue.8 , pp. 1409-1416
    • Hu, J.1    Fink, D.2    Mata, M.3
  • 40
    • 33644904656 scopus 로고    scopus 로고
    • Microarray analysis of gene expression patterns in adult spinal motoneurons after different types of axonal injuries
    • Yang Y.; Xie Y.; Chai H.; Fan M.; Liu S.; Liu H.; Bruce I.; Wu W. Microarray analysis of gene expression patterns in adult spinal motoneurons after different types of axonal injuries. Brain Res., 2006, 1075(1), 1-12.
    • (2006) Brain Res , vol.1075 , Issue.1 , pp. 1-12
    • Yang, Y.1    Xie, Y.2    Chai, H.3    Fan, M.4    Liu, S.5    Liu, H.6    Bruce, I.7    Wu, W.8
  • 41
    • 0031933378 scopus 로고    scopus 로고
    • Changes in the mRNA expression pattern, with special reference to calcitonin gene-related peptide, after axonal injuries in rat motoneurons depends on age and type of injury
    • Piehl F.; Hammarberg H.; Tabar G.; Hokfelt T.; Cullheim S. Changes in the mRNA expression pattern, with special reference to calcitonin gene-related peptide, after axonal injuries in rat motoneurons depends on age and type of injury. Exp. Brain Res., 1998, 119(2), 191-204.
    • (1998) Exp. Brain Res , vol.119 , Issue.2 , pp. 191-204
    • Piehl, F.1    Hammarberg, H.2    Tabar, G.3    Hokfelt, T.4    Cullheim, S.5
  • 42
    • 0030271362 scopus 로고    scopus 로고
    • Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: A comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS)
    • Wu W. Potential roles of gene expression change in adult rat spinal motoneurons following axonal injury: a comparison among c-jun, off-affinity nerve growth factor receptor (LNGFR), and nitric oxide synthase (NOS). Exp. Neurol., 1996, 141 (2), 190-200.
    • (1996) Exp. Neurol , vol.141 , Issue.2 , pp. 190-200
    • Wu, W.1
  • 43
    • 0025916613 scopus 로고
    • Calcitonin Gene-related Peptide (CGRP)-like immunoreactivity and cgrp mrna in rat spinal cord motoneurons after different types of lesions
    • Piehl F.; Arvidsson U.; Johnson H.; Cullheim S.; Villar M.; Dagerlind A.; Terenius L.; Hokfelt T.; Ulfhake B. Calcitonin Gene-related Peptide (CGRP)-like immunoreactivity and cgrp mrna in rat spinal cord motoneurons after different types of lesions. Eur. J. Neurosci., 1991, 3(8), 737-757.
    • (1991) Eur. J. Neurosci , vol.3 , Issue.8 , pp. 737-757
    • Piehl, F.1    Arvidsson, U.2    Johnson, H.3    Cullheim, S.4    Villar, M.5    Dagerlind, A.6    Terenius, L.7    Hokfelt, T.8    Ulfhake, B.9
  • 44
    • 0029123638 scopus 로고
    • Expression of NMDA receptor mRNAs in rat motoneurons is down-regulated after axotomy
    • Piehl F.; Tabar G.; Cullheim S. Expression of NMDA receptor mRNAs in rat motoneurons is down-regulated after axotomy. Eur. J. Neurosci., 1995, 7(10), 2101-2110.
    • (1995) Eur. J. Neurosci , vol.7 , Issue.10 , pp. 2101-2110
    • Piehl, F.1    Tabar, G.2    Cullheim, S.3
  • 45
    • 0345276559 scopus 로고    scopus 로고
    • NMDA receptor regulation of nNOS phosphorylation and induction of neuron death
    • Rameau G. A.; Chiu L. Y.; Ziff E. B. NMDA receptor regulation of nNOS phosphorylation and induction of neuron death. Neurobiol. Aging, 2003, 24(8), 1123-1133.
    • (2003) Neurobiol. Aging , vol.24 , Issue.8 , pp. 1123-1133
    • Rameau, G.A.1    Chiu, L.Y.2    Ziff, E.B.3
  • 46
    • 0037366380 scopus 로고    scopus 로고
    • Expression of nitric oxide synthase and 27-kD heat shock protein in motor neurons of ventral root-avulsed rats
    • He J. W.; Hirata K.; Wang S.; Kawabuchi M. Expression of nitric oxide synthase and 27-kD heat shock protein in motor neurons of ventral root-avulsed rats. Arch. Histol. Cytol., 2003, 66(1), 83-93.
    • (2003) Arch. Histol. Cytol , vol.66 , Issue.1 , pp. 83-93
    • He, J.W.1    Hirata, K.2    Wang, S.3    Kawabuchi, M.4
  • 47
    • 0032511732 scopus 로고    scopus 로고
    • Expression of insulin-like growth factors and corresponding binding proteins (IGFBP 1-6) in rat spinal cord and peripheral nerve after axonal injuries
    • Hammarberg H.; Risling M.; Hokfelt T.; Cullheim S.; Piehl F. Expression of insulin-like growth factors and corresponding binding proteins (IGFBP 1-6) in rat spinal cord and peripheral nerve after axonal injuries. J. Comp. Neurol., 1998, 400(1), 57-72.
    • (1998) J. Comp. Neurol , vol.400 , Issue.1 , pp. 57-72
    • Hammarberg, H.1    Risling, M.2    Hokfelt, T.3    Cullheim, S.4    Piehl, F.5
  • 48
    • 0033771487 scopus 로고    scopus 로고
    • Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat
    • Hammarberg H.; Piehl F.; Risling M.; Cullheim S. Differential regulation of trophic factor receptor mRNAs in spinal motoneurons after sciatic nerve transection and ventral root avulsion in the rat. J. Comp. Neurol., 2000, 426(4), 587-601.
    • (2000) J. Comp. Neurol , vol.426 , Issue.4 , pp. 587-601
    • Hammarberg, H.1    Piehl, F.2    Risling, M.3    Cullheim, S.4
  • 49
    • 0030913939 scopus 로고    scopus 로고
    • The effects of remaining axons on motoneuron survival and NOS expression following axotomy in the adult rat
    • Gu Y.; Spasic Z.; Wu W. The effects of remaining axons on motoneuron survival and NOS expression following axotomy in the adult rat. Dev. Neurosci., 1997, 19(3), 255-259.
    • (1997) Dev. Neurosci , vol.19 , Issue.3 , pp. 255-259
    • Gu, Y.1    Spasic, Z.2    Wu, W.3
  • 50
    • 0023120715 scopus 로고
    • Regeneration by supernumerary axons with synaptic terminals in spinal motoneurons of cats
    • Havton L.; Kellerth J. O. Regeneration by supernumerary axons with synaptic terminals in spinal motoneurons of cats. Nature, 1987, 325(6106), 711-714.
    • (1987) Nature , vol.325 , Issue.6106 , pp. 711-714
    • Havton, L.1    Kellerth, J.O.2
  • 51
    • 0022400301 scopus 로고
    • Dendraxons' in regenerating motoneurons in the cat: Do dendrites generate new axons after central axotomy?
    • Linda H.; Risling M.; Cullheim S. 'Dendraxons' in regenerating motoneurons in the cat: do dendrites generate new axons after central axotomy? Brain Res., 1985, 358(1-2), 329-333.
    • (1985) Brain Res , vol.358 , Issue.1-2 , pp. 329-333
    • Linda, H.1    Risling, M.2    Cullheim, S.3
  • 52
    • 0028246867 scopus 로고
    • Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord
    • Li Y.; Raisman G. Schwann cells induce sprouting in motor and sensory axons in the adult rat spinal cord. J. Neurosci., 1994, 14(7), 4050-4063.
    • (1994) J. Neurosci , vol.14 , Issue.7 , pp. 4050-4063
    • Li, Y.1    Raisman, G.2
  • 53
    • 0032413178 scopus 로고    scopus 로고
    • Schwann cells, neurotrophic factors, and peripheral nerve regeneration
    • Frostick S. P.; Yin Q.; Kemp G. J. Schwann cells, neurotrophic factors, and peripheral nerve regeneration. Microsurgery, 1998, 18(7), 397-405.
    • (1998) Microsurgery , vol.18 , Issue.7 , pp. 397-405
    • Frostick, S.P.1    Yin, Q.2    Kemp, G.J.3
  • 54
    • 5644229846 scopus 로고    scopus 로고
    • Neurotrophic factors and amyotrophic lateral sclerosis
    • Ekestern E. Neurotrophic factors and amyotrophic lateral sclerosis. Neurodegener. Dis., 2004, 1(2-3), 88-100.
    • (2004) Neurodegener. Dis , vol.1 , Issue.2-3 , pp. 88-100
    • Ekestern, E.1
  • 55
    • 0026598991 scopus 로고
    • Aberrant regeneration of motor axons into the pia mater after ventral root neuroma formation
    • Risling M.; Sorbye K.; Cullheim S. Aberrant regeneration of motor axons into the pia mater after ventral root neuroma formation. Brain Res., 1992, 570(1-2), 27-34.
    • (1992) Brain Res , vol.570 , Issue.1-2 , pp. 27-34
    • Risling, M.1    Sorbye, K.2    Cullheim, S.3
  • 56
    • 0021327553 scopus 로고
    • Invasion of the L7 ventral root and spinal pia mater by new axons after sciatic nerve division in kittens
    • Risling M.; Hildebrand C.; Cullheim S. Invasion of the L7 ventral root and spinal pia mater by new axons after sciatic nerve division in kittens. Exp. Neurol., 1984, 83(1), 84-97.
    • (1984) Exp. Neurol , vol.83 , Issue.1 , pp. 84-97
    • Risling, M.1    Hildebrand, C.2    Cullheim, S.3
  • 57
    • 0031026709 scopus 로고    scopus 로고
    • Nerve fibre regeneration across the peripheral-central transitional zone
    • Carlstedt T. Nerve fibre regeneration across the peripheral-central transitional zone. J. Anat., 1997, 190 ( Pt 1)51-56.
    • (1997) J. Anat , vol.190 , Issue.PART 1 , pp. 51-56
    • Carlstedt, T.1
  • 58
    • 0023413208 scopus 로고
    • Neurotropism and neurotrophism
    • Brushart T. M. Neurotropism and neurotrophism. J. Hand Surg., 1987, 12A808-.
    • (1987) J. Hand Surg , vol.12 A , pp. 808
    • Brushart, T.M.1
  • 59
    • 0024374643 scopus 로고
    • Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat
    • Cullheim S.; Carlstedt T.; Linda H.; Risling M.; Ulfhake B. Motoneurons reinnervate skeletal muscle after ventral root implantation into the spinal cord of the cat. Neuroscience, 1989, 29(3), 725-73.
    • (1989) Neuroscience , vol.29 , Issue.3 , pp. 725-773
    • Cullheim, S.1    Carlstedt, T.2    Linda, H.3    Risling, M.4    Ulfhake, B.5
  • 60
    • 0027258846 scopus 로고
    • Functional recovery in primates with brachial plexus injury after spinal cord implantation of avulsed ventral roots
    • Carlstedt T. P.; Hallin R. G.; Hedstrom K. G.; Nilsson-Remahl I. A. Functional recovery in primates with brachial plexus injury after spinal cord implantation of avulsed ventral roots. J. Neurol. Neurosurg. Psychiatry, 1993, 56(6), 649-654.
    • (1993) J. Neurol. Neurosurg. Psychiatry , vol.56 , Issue.6 , pp. 649-654
    • Carlstedt, T.P.1    Hallin, R.G.2    Hedstrom, K.G.3    Nilsson-Remahl, I.A.4
  • 61
    • 33748266273 scopus 로고    scopus 로고
    • Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair
    • Hoang T. X.; Pikov V.; Havton L. A. Functional reinnervation of the rat lower urinary tract after cauda equina injury and repair. J. Neurosci., 2006, 26(34), 8672-8679.
    • (2006) J. Neurosci , vol.26 , Issue.34 , pp. 8672-8679
    • Hoang, T.X.1    Pikov, V.2    Havton, L.A.3
  • 62
  • 64
    • 47349099688 scopus 로고    scopus 로고
    • Motor nerve graft is better than sensory nerve graft for survival and regeneration of motoneurons after spinal root avulsion in adult rats
    • Chu T. H.; Du Y.; Wu W. Motor nerve graft is better than sensory nerve graft for survival and regeneration of motoneurons after spinal root avulsion in adult rats. Exp. Neurol., 2008, 212(2), 562-565.
    • (2008) Exp. Neurol , vol.212 , Issue.2 , pp. 562-565
    • Chu, T.H.1    Du, Y.2    Wu, W.3
  • 65
    • 0024419186 scopus 로고
    • Neurotrophic molecules
    • Snider W. D.; Johnson E. M. Jr. Neurotrophic molecules. Ann. Neurol., 1989, 26(4), 489-506.
    • (1989) Ann. Neurol , vol.26 , Issue.4 , pp. 489-506
    • Snider, W.D.1    Johnson Jr., E.M.2
  • 66
    • 0023688111 scopus 로고
    • What, if anything, is a neurotrophic factor?
    • Barde Y. A. What, if anything, is a neurotrophic factor? Trends Neurosci., 1988, 11(8), 343-346.
    • (1988) Trends Neurosci , vol.11 , Issue.8 , pp. 343-346
    • Barde, Y.A.1
  • 67
    • 76549235314 scopus 로고
    • Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo
    • Levi-Montalcini R.; Hamburger V. Selective growth stimulating effects of mouse sarcoma on the sensory and sympathetic nervous system of the chick embryo. J. Exp. Zool., 1951, 116(2), 321-361.
    • (1951) J. Exp. Zool , vol.116 , Issue.2 , pp. 321-361
    • Levi-Montalcini, R.1    Hamburger, V.2
  • 68
    • 0031827384 scopus 로고    scopus 로고
    • Neurotrophins, neurones and peripheral nerve regeneration
    • Yin Q.; Kemp G. J.; Frostick S. P. Neurotrophins, neurones and peripheral nerve regeneration. J. Hand Surg., [Br. ], 1998, 23(4), 433-437.
    • (1998) J. Hand Surg., [Br. ] , vol.23 , Issue.4 , pp. 433-437
    • Yin, Q.1    Kemp, G.J.2    Frostick, S.P.3
  • 69
    • 0027284669 scopus 로고
    • Surgery for Brachial Plexus Injury
    • Birch R. Surgery for Brachial Plexus Injury. J. Bone Joint Surg., 1993, 75B, 346-348.
    • (1993) J. Bone Joint Surg , vol.75 B , pp. 346-348
    • Birch, R.1
  • 71
    • 0014584518 scopus 로고
    • The nerve growth factor: Purification as a 30,000-molecular-weight protein
    • Bocchini V.; Angeletti P. U. The nerve growth factor: purification as a 30,000-molecular-weight protein. Proc. Natl. Acad. Sci. USA, 1969, 64(2), 787-794.
    • (1969) Proc. Natl. Acad. Sci. USA , vol.64 , Issue.2 , pp. 787-794
    • Bocchini, V.1    Angeletti, P.U.2
  • 72
    • 0021767870 scopus 로고
    • Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues
    • Heumann R.; Korsching S.; Scott J.; Thoenen H. Relationship between levels of nerve growth factor (NGF) and its messenger RNA in sympathetic ganglia and peripheral target tissues. EMBO J., 1984, 3(13), 3183-3189.
    • (1984) EMBO J , vol.3 , Issue.13 , pp. 3183-3189
    • Heumann, R.1    Korsching, S.2    Scott, J.3    Thoenen, H.4
  • 73
    • 0344106663 scopus 로고
    • Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation
    • Korsching S.; Auburger G.; Heumann R.; Scott J.; Thoenen H. Levels of nerve growth factor and its mRNA in the central nervous system of the rat correlate with cholinergic innervation. EMBO J., 1985, 4(6), 1389-1393.
    • (1985) EMBO J , vol.4 , Issue.6 , pp. 1389-1393
    • Korsching, S.1    Auburger, G.2    Heumann, R.3    Scott, J.4    Thoenen, H.5
  • 74
    • 0021152619 scopus 로고
    • A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells
    • Chandler C. E.; Parsons L. M.; Hosang M.; Shooter E. M. A monoclonal antibody modulates the interaction of nerve growth factor with PC12 cells. J. Biol. Chem, 1984, 259(11), 6882-6889.
    • (1984) J. Biol. Chem , vol.259 , Issue.11 , pp. 6882-6889
    • Chandler, C.E.1    Parsons, L.M.2    Hosang, M.3    Shooter, E.M.4
  • 75
    • 0023029157 scopus 로고
    • Isolation of embryonic chick motoneurons and their survival in vitro
    • O'Brien R. J.; Fischbach G. D. Isolation of embryonic chick motoneurons and their survival in vitro. J. Neurosci., 1986, 6(11), 3265-3274.
    • (1986) J. Neurosci , vol.6 , Issue.11 , pp. 3265-3274
    • O'Brien, R.J.1    Fischbach, G.D.2
  • 76
    • 0023427627 scopus 로고
    • Fluorescence-activated cell sorting of embryonic mouse and rat motoneurons and their long-term survival in vitro
    • Schaffner A. E.; St John P. A.; Barker J. L. Fluorescence-activated cell sorting of embryonic mouse and rat motoneurons and their long-term survival in vitro. J. Neurosci., 1987, 7(10), 3088-3104.
    • (1987) J. Neurosci , vol.7 , Issue.10 , pp. 3088-3104
    • Schaffner, A.E.1    St John, P.A.2    Barker, J.L.3
  • 77
    • 0027195615 scopus 로고
    • The neurotrophic factor concept: A reexamination
    • Korsching S. The neurotrophic factor concept: a reexamination. J. Neurosci., 1993, 73(7), 2739-2748.
    • (1993) J. Neurosci , vol.73 , Issue.7 , pp. 2739-2748
    • Korsching, S.1
  • 78
    • 0030220893 scopus 로고    scopus 로고
    • Neurotrophic survival molecules for motoneurons: An embarrassment of riches
    • Oppenheim R. W. Neurotrophic survival molecules for motoneurons: an embarrassment of riches. Neuron, 1996, 17(2), 195-197.
    • (1996) Neuron , vol.17 , Issue.2 , pp. 195-197
    • Oppenheim, R.W.1
  • 79
    • 0025524602 scopus 로고
    • The nerve growth factor family
    • Barde Y. A. The nerve growth factor family. Prog. Growth Factor Res., 1990, 2(4), 237-248.
    • (1990) Prog. Growth Factor Res , vol.2 , Issue.4 , pp. 237-248
    • Barde, Y.A.1
  • 80
    • 33746647820 scopus 로고    scopus 로고
    • Neurotrophin signaling: Many exciting surprises!
    • Arevalo J. C.; Wu S. H. Neurotrophin signaling: many exciting surprises! Cell Mol. Life Sci., 2006, 63(13), 1523-1537.
    • (2006) Cell Mol. Life Sci , vol.63 , Issue.13 , pp. 1523-1537
    • Arevalo, J.C.1    Wu, S.H.2
  • 81
    • 33645910231 scopus 로고    scopus 로고
    • Dissecting the diverse actions of pro- and mature neurotrophins
    • Hempstead B. L. Dissecting the diverse actions of pro- and mature neurotrophins. Curr. Alzheimer Res., 2006, 3(1), 19-24.
    • (2006) Curr. Alzheimer Res , vol.3 , Issue.1 , pp. 19-24
    • Hempstead, B.L.1
  • 82
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point for many signalling pathways
    • Chao M. V. Neurotrophins and their receptors: a convergence point for many signalling pathways. Nat. Rev. Neurosci., 2003, 4(4), 299-309.
    • (2003) Nat. Rev. Neurosci , vol.4 , Issue.4 , pp. 299-309
    • Chao, M.V.1
  • 83
    • 23044488902 scopus 로고    scopus 로고
    • The yin and yang of neurotrophin action
    • Lu B.; Pang P. T.; Woo N. H. The yin and yang of neurotrophin action. Nat. Rev. Neurosci., 2005, 6(8), 603-614.
    • (2005) Nat. Rev. Neurosci , vol.6 , Issue.8 , pp. 603-614
    • Lu, B.1    Pang, P.T.2    Woo, N.H.3
  • 84
    • 0033564393 scopus 로고    scopus 로고
    • TrkB isoforms with distinct neurotrophin specificities are expressed in predominantly nonoverlapping populations of avian dorsal root ganglion neurons
    • Boeshore K. L.; Luckey C. N.; Zigmond R. E.; Large T. H. TrkB isoforms with distinct neurotrophin specificities are expressed in predominantly nonoverlapping populations of avian dorsal root ganglion neurons. J. Neurosci., 1999, 19(12), 4739-4747.
    • (1999) J. Neurosci , vol.19 , Issue.12 , pp. 4739-4747
    • Boeshore, K.L.1    Luckey, C.N.2    Zigmond, R.E.3    Large, T.H.4
  • 85
    • 0041488911 scopus 로고    scopus 로고
    • Trk receptors: Roles in neuronal signal transduction
    • Huang E. J.; Reichardt L. F. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem., 2003, 72, 609-642.
    • (2003) Annu. Rev. Biochem , vol.72 , pp. 609-642
    • Huang, E.J.1    Reichardt, L.F.2
  • 86
    • 0035851290 scopus 로고    scopus 로고
    • GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia
    • Josephson A.; Widenfalk J.; Trifunovski A.; Widmer H. R.; Olson L.; Spenger C. GDNF and NGF family members and receptors in human fetal and adult spinal cord and dorsal root ganglia. J. Comp. Neurol., 2001, 440(2), 204-217.
    • (2001) J. Comp. Neurol , vol.440 , Issue.2 , pp. 204-217
    • Josephson, A.1    Widenfalk, J.2    Trifunovski, A.3    Widmer, H.R.4    Olson, L.5    Spenger, C.6
  • 87
    • 0027481752 scopus 로고
    • Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo
    • Koliatsos V. E.; Clatterbuck R. E.; Winslow J. W.; Cayouette M. H.; Price D. L. Evidence that brain-derived neurotrophic factor is a trophic factor for motor neurons in vivo. Neuron, 1993, 70(3), 359-367.
    • (1993) Neuron , vol.70 , Issue.3 , pp. 359-367
    • Koliatsos, V.E.1    Clatterbuck, R.E.2    Winslow, J.W.3    Cayouette, M.H.4    Price, D.L.5
  • 88
    • 0027094145 scopus 로고
    • Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death
    • Oppenheim R. W.; Yin Q. W.; Prevette D.; Yan Q. Brain-derived neurotrophic factor rescues developing avian motoneurons from cell death. Nature, 1992, 360(6406), 755-757.
    • (1992) Nature , vol.360 , Issue.6406 , pp. 755-757
    • Oppenheim, R.W.1    Yin, Q.W.2    Prevette, D.3    Yan, Q.4
  • 89
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner M.; Holtmann B.; Kolbeck R.; Thoenen H.; Barde Y. A. Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature, 1992, 360(6406), 757-759.
    • (1992) Nature , vol.360 , Issue.6406 , pp. 757-759
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.A.5
  • 90
    • 0141448981 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo
    • Boyd J. G.; Gordon T. Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor sustain the axonal regeneration of chronically axotomized motoneurons in vivo. Exp. Neurol., 2003, 183(2), 610-619.
    • (2003) Exp. Neurol , vol.183 , Issue.2 , pp. 610-619
    • Boyd, J.G.1    Gordon, T.2
  • 91
    • 0030762723 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
    • Novikov L.; Novikova L.; Kellerth J. O. Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo. Neuroscience, 1997, 79(3), 765-774
    • (1997) Neuroscience , vol.79 , Issue.3 , pp. 765-774
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 92
    • 0036460528 scopus 로고    scopus 로고
    • Focal application of neutralizing antibodies to soluble neurotrophic factors reduces collateral axonal branching after peripheral nerve lesion
    • Streppel M.; Azzolin N.; Dohm S.; Guntinas-Lichius O.; Haas C.; Grothe C.; Wevers A.; Neiss W. F.; Angelov D. N. Focal application of neutralizing antibodies to soluble neurotrophic factors reduces collateral axonal branching after peripheral nerve lesion. Eur. J. Neurosci., 2002, 15(8), 1327-1342.
    • (2002) Eur. J. Neurosci , vol.15 , Issue.8 , pp. 1327-1342
    • Streppel, M.1    Azzolin, N.2    Dohm, S.3    Guntinas-Lichius, O.4    Haas, C.5    Grothe, C.6    Wevers, A.7    Neiss, W.F.8    Angelov, D.N.9
  • 93
    • 0034507954 scopus 로고    scopus 로고
    • Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents
    • Zhang J. Y.; Luo X. G.; Xian C. J.; Liu Z. H.; Zhou X. F. Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents. Eur. J. Neurosci., 2000, 12(12), 4171-4180.
    • (2000) Eur. J. Neurosci , vol.12 , Issue.12 , pp. 4171-4180
    • Zhang, J.Y.1    Luo, X.G.2    Xian, C.J.3    Liu, Z.H.4    Zhou, X.F.5
  • 94
    • 0038045085 scopus 로고    scopus 로고
    • GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats
    • Wu W.; Li L.; Yick L. W.; Chai H.; Xie Y.; Yang Y.; Prevette D. M.; Oppenheim R. W. GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats. J. Neurotrauma, 2003, 20(6), 603-612.
    • (2003) J. Neurotrauma , vol.20 , Issue.6 , pp. 603-612
    • Wu, W.1    Li, L.2    Yick, L.W.3    Chai, H.4    Xie, Y.5    Yang, Y.6    Prevette, D.M.7    Oppenheim, R.W.8
  • 95
    • 0032873649 scopus 로고    scopus 로고
    • Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat
    • Chai H.; Wu W.; So K. F.; Prevette D. M.; Oppenheim R. W. Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat. Neurosci. Lett., 1999, 274(3), 147-150.
    • (1999) Neurosci. Lett , vol.274 , Issue.3 , pp. 147-150
    • Chai, H.1    Wu, W.2    So, K.F.3    Prevette, D.M.4    Oppenheim, R.W.5
  • 96
    • 0036460111 scopus 로고    scopus 로고
    • A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor
    • Boyd J. G.; Gordon T. A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor. Eur. J. Neurosci., 2002, 15(4), 613-626.
    • (2002) Eur. J. Neurosci , vol.15 , Issue.4 , pp. 613-626
    • Boyd, J.G.1    Gordon, T.2
  • 97
    • 2942535957 scopus 로고    scopus 로고
    • Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases
    • Yamauchi J.; Chan J. R.; Shooter E. M. Neurotrophins regulate Schwann cell migration by activating divergent signaling pathways dependent on Rho GTPases. Proc. Natl. Acad. Sci. USA, 2004, 101(23), 8774-8779.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.23 , pp. 8774-8779
    • Yamauchi, J.1    Chan, J.R.2    Shooter, E.M.3
  • 99
    • 0028279370 scopus 로고
    • Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse
    • Li L.; Oppenheim R. W.; Lei M.; Houenou L. J. Neurotrophic agents prevent motoneuron death following sciatic nerve section in the neonatal mouse. J. Neurobiol., 1994, 25(7), 759-766.
    • (1994) J. Neurobiol , vol.25 , Issue.7 , pp. 759-766
    • Li, L.1    Oppenheim, R.W.2    Lei, M.3    Houenou, L.J.4
  • 101
    • 20644438664 scopus 로고    scopus 로고
    • Neurotrophin-4/5 is required for the early growth of regenerating axons in peripheral nerves
    • English A. W.; Meador W.; Carrasco D. I. Neurotrophin-4/5 is required for the early growth of regenerating axons in peripheral nerves. Eur. J. Neurosci., 2005, 21(10), 2624-2634.
    • (2005) Eur. J. Neurosci , vol.21 , Issue.10 , pp. 2624-2634
    • English, A.W.1    Meador, W.2    Carrasco, D.I.3
  • 102
    • 0345305732 scopus 로고    scopus 로고
    • Effect of NT-4 and BDNF delivery to damaged sciatic nerves on pheno-typic recovery of fast and slow muscles fibres
    • Simon M.; Porter R.; Brown R.; Coulton G. R.; Terenghi G. Effect of NT-4 and BDNF delivery to damaged sciatic nerves on pheno-typic recovery of fast and slow muscles fibres. Eur. J. Neurosci., 2003, 18(9), 2460-2466.
    • (2003) Eur. J. Neurosci , vol.18 , Issue.9 , pp. 2460-2466
    • Simon, M.1    Porter, R.2    Brown, R.3    Coulton, G.R.4    Terenghi, G.5
  • 103
    • 0032702435 scopus 로고    scopus 로고
    • Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration
    • Corse A. M.; Bilak M. M.; Bilak S. R.; Lehar M.; Rothstein J. D.; Kuncl R. W. Preclinical testing of neuroprotective neurotrophic factors in a model of chronic motor neuron degeneration. Neurobiol. Dis., 1999, 6(5), 335-346.
    • (1999) Neurobiol. Dis , vol.6 , Issue.5 , pp. 335-346
    • Corse, A.M.1    Bilak, M.M.2    Bilak, S.R.3    Lehar, M.4    Rothstein, J.D.5    Kuncl, R.W.6
  • 104
    • 0035947384 scopus 로고    scopus 로고
    • Malonate-induced cortico-motoneuron death is attenuated by NT-4, but not by BDNF or NT-3
    • Van Westerlaak M. G.; Bar P. R.; Cools A. R.; Joosten E. A. Malonate-induced cortico-motoneuron death is attenuated by NT-4, but not by BDNF or NT-3. Neuroreport, 2001, 12(7), 1355-1358.
    • (2001) Neuroreport , vol.12 , Issue.7 , pp. 1355-1358
    • Van Westerlaak, M.G.1    Bar, P.R.2    Cools, A.R.3    Joosten, E.A.4
  • 105
    • 33749010358 scopus 로고    scopus 로고
    • Neurotrophin-regulated signalling pathways
    • Reichardt L. F. Neurotrophin-regulated signalling pathways. Philos. Trans. R. Soc. Lond B Biol. Sci., 2006, 361(1473), 1545-1564.
    • (2006) Philos. Trans. R. Soc. Lond B Biol. Sci , vol.361 , Issue.1473 , pp. 1545-1564
    • Reichardt, L.F.1
  • 109
    • 0026694239 scopus 로고
    • Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration
    • Sendtner M.; Stockli K. A.; Thoenen H. Synthesis and localization of ciliary neurotrophic factor in the sciatic nerve of the adult rat after lesion and during regeneration. J. Cell Biol., 1992, 118(1), 139-148.
    • (1992) J. Cell Biol , vol.118 , Issue.1 , pp. 139-148
    • Sendtner, M.1    Stockli, K.A.2    Thoenen, H.3
  • 111
    • 0027484249 scopus 로고
    • Disruption of the CNTF gene results in motor neuron degeneration
    • Masu Y.; Wolf E.; Holtmann B.; Sendtner M.; Brem G.; Thoenen H. Disruption of the CNTF gene results in motor neuron degeneration. Nature, 1993, 365(6441), 27-32.
    • (1993) Nature , vol.365 , Issue.6441 , pp. 27-32
    • Masu, Y.1    Wolf, E.2    Holtmann, B.3    Sendtner, M.4    Brem, G.5    Thoenen, H.6
  • 112
    • 0030758501 scopus 로고    scopus 로고
    • Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice
    • Sendtner M.; Gotz R.; Holtmann B.; Thoenen H. Endogenous ciliary neurotrophic factor is a lesion factor for axotomized motoneurons in adult mice. J. Neurosci., 1997, 17(18), 6999-7006.
    • (1997) J. Neurosci , vol.17 , Issue.18 , pp. 6999-7006
    • Sendtner, M.1    Gotz, R.2    Holtmann, B.3    Thoenen, H.4
  • 113
    • 0037148523 scopus 로고    scopus 로고
    • Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult
    • Schweizer U.; Gunnersen J.; Karch C.; Wiese S.; Holtmann B.; Takeda K.; Akira S.; Sendtner M. Conditional gene ablation of Stat3 reveals differential signaling requirements for survival of motoneurons during development and after nerve injury in the adult. J. Cell Biol., 2002, 156(2), 287-297.
    • (2002) J. Cell Biol , vol.156 , Issue.2 , pp. 287-297
    • Schweizer, U.1    Gunnersen, J.2    Karch, C.3    Wiese, S.4    Holtmann, B.5    Takeda, K.6    Akira, S.7    Sendtner, M.8
  • 115
    • 0025325548 scopus 로고
    • Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy
    • Sendtner M.; Kreutzberg G. W.; Thoenen H. Ciliary neurotrophic factor prevents the degeneration of motor neurons after axotomy. Nature, 1990, 345(6274), 440-441.
    • (1990) Nature , vol.345 , Issue.6274 , pp. 440-441
    • Sendtner, M.1    Kreutzberg, G.W.2    Thoenen, H.3
  • 116
    • 3042631880 scopus 로고    scopus 로고
    • Cytokines, growth factors and sprouting at the neuromuscular junction
    • English A. W. Cytokines, growth factors and sprouting at the neuromuscular junction. J. Neurocytol., 2003, 32(5-8), 943-960.
    • (2003) J. Neurocytol , vol.32 , Issue.5-8 , pp. 943-960
    • English, A.W.1
  • 117
    • 0036829006 scopus 로고    scopus 로고
    • Neurotrophins: From enthusiastic expectations through sobering experiences to rational therapeutic approaches
    • Thoenen H.; Sendtner M. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nat. Neurosci., 2002, 5 (Suppl), 1046-1050.
    • (2002) Nat. Neurosci , vol.5 , Issue.SUPPL. , pp. 1046-1050
    • Thoenen, H.1    Sendtner, M.2
  • 118
    • 0026550179 scopus 로고
    • Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic mo- toneurons in vitro
    • Martinou J. C.; Martinou I.; Kato A. C. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic mo- toneurons in vitro. Neuron, 1992, 8(4), 737-744.
    • (1992) Neuron , vol.8 , Issue.4 , pp. 737-744
    • Martinou, J.C.1    Martinou, I.2    Kato, A.C.3
  • 119
    • 0029782556 scopus 로고    scopus 로고
    • Leukemia inhibitory factor is a myotrophic and neurotrophic agent that enhances the reinnervation of muscle in the rat
    • Finkelstein D. I.; Bartlett P. F.; Horne M. K.; Cheema S. S. Leukemia inhibitory factor is a myotrophic and neurotrophic agent that enhances the reinnervation of muscle in the rat. J. Neurosci. Res., 1996, 46(1), 122-128.
    • (1996) J. Neurosci. Res , vol.46 , Issue.1 , pp. 122-128
    • Finkelstein, D.I.1    Bartlett, P.F.2    Horne, M.K.3    Cheema, S.S.4
  • 120
    • 0030964023 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials
    • Gadient R. A.; Otten U. H. Interleukin-6 (IL-6)-a molecule with both beneficial and destructive potentials. Prog. Neurobiol., 1997, 52(5), 379-390.
    • (1997) Prog. Neurobiol , vol.52 , Issue.5 , pp. 379-390
    • Gadient, R.A.1    Otten, U.H.2
  • 121
    • 0034234414 scopus 로고    scopus 로고
    • Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration
    • Streit W. J.; Hurley S. D.; McGraw T. S.; Semple-Rowland S. L. Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration. J. Neurosci. Res., 2000, 61(1), 10-20.
    • (2000) J. Neurosci. Res , vol.61 , Issue.1 , pp. 10-20
    • Streit, W.J.1    Hurley, S.D.2    McGraw, T.S.3    Semple-Rowland, S.L.4
  • 122
    • 0029894833 scopus 로고    scopus 로고
    • Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma
    • Hirota H.; Kiyama H.; Kishimoto T.; Taga T. Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. J. Exp. Med., 1996, 183(6), 2627-2634.
    • (1996) J. Exp. Med , vol.183 , Issue.6 , pp. 2627-2634
    • Hirota, H.1    Kiyama, H.2    Kishimoto, T.3    Taga, T.4
  • 127
    • 0344153775 scopus 로고    scopus 로고
    • Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse
    • Zang D. W.; Cheema S. S. Leukemia inhibitory factor promotes recovery of locomotor function following spinal cord injury in the mouse. J. Neurotrauma, 2003, 20(11), 1215-1222.
    • (2003) J. Neurotrauma , vol.20 , Issue.11 , pp. 1215-1222
    • Zang, D.W.1    Cheema, S.S.2
  • 128
    • 0033135389 scopus 로고    scopus 로고
    • Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury
    • Blesch A.; Uy H. S.; Grill R. J.; Cheng J. G.; Patterson P. H.; Tuszynski M. H. Leukemia inhibitory factor augments neurotrophin expression and corticospinal axon growth after adult CNS injury. J. Neurosci., 1999, 19(9), 3556-3566.
    • (1999) J. Neurosci , vol.19 , Issue.9 , pp. 3556-3566
    • Blesch, A.1    Uy, H.S.2    Grill, R.J.3    Cheng, J.G.4    Patterson, P.H.5    Tuszynski, M.H.6
  • 129
    • 0033773180 scopus 로고    scopus 로고
    • The transforming growth factor-betas: Structure, signaling, and roles in nervous system development and functions
    • Bottner M.; Krieglstein K.; Unsicker K. The transforming growth factor-betas: structure, signaling, and roles in nervous system development and functions. J. Neurochem., 2000, 75(6), 2227-2240.
    • (2000) J. Neurochem , vol.75 , Issue.6 , pp. 2227-2240
    • Bottner, M.1    Krieglstein, K.2    Unsicker, K.3
  • 130
    • 0242366443 scopus 로고    scopus 로고
    • Transforming growth factor-beta: A neuroprotective factor in cerebral ischemia
    • Dhandapani K. M.; Brann D. W. Transforming growth factor-beta: a neuroprotective factor in cerebral ischemia. Cell Biochem. Biophys., 2003, 39(1), 13-22.
    • (2003) Cell Biochem. Biophys , vol.39 , Issue.1 , pp. 13-22
    • Dhandapani, K.M.1    Brann, D.W.2
  • 132
    • 33947594300 scopus 로고    scopus 로고
    • BMP6 is axonally transported by motoneurons and supports their survival in vitro
    • Wang P. Y.; Koishi K.; McLennan I. S. BMP6 is axonally transported by motoneurons and supports their survival in vitro. Mol. Cell Neurosci., 2007, 34(4), 653-661
    • (2007) Mol. Cell Neurosci , vol.34 , Issue.4 , pp. 653-661
    • Wang, P.Y.1    Koishi, K.2    McLennan, I.S.3
  • 133
    • 0036581222 scopus 로고    scopus 로고
    • The GDNF family: Signalling, biological functions and therapeutic value
    • Airaksinen M. S.; Saarma M. The GDNF family: signalling, biological functions and therapeutic value. Nat. Rev. Neurosci., 2002, 3(5), 383-394.
    • (2002) Nat. Rev. Neurosci , vol.3 , Issue.5 , pp. 383-394
    • Airaksinen, M.S.1    Saarma, M.2
  • 134
    • 0033597817 scopus 로고    scopus 로고
    • Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells
    • Trupp M.; Scott R.; Whittemore S. R.; Ibanez C. F. Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cells. J. Biol. Chem., 1999, 274(30), 20885-20894.
    • (1999) J. Biol. Chem , vol.274 , Issue.30 , pp. 20885-20894
    • Trupp, M.1    Scott, R.2    Whittemore, S.R.3    Ibanez, C.F.4
  • 135
    • 0038488948 scopus 로고    scopus 로고
    • The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands
    • Paratcha G.; Ledda F.; Ibanez C. F. The neural cell adhesion molecule NCAM is an alternative signaling receptor for GDNF family ligands. Cell, 2003, 113(7), 867-879.
    • (2003) Cell , vol.113 , Issue.7 , pp. 867-879
    • Paratcha, G.1    Ledda, F.2    Ibanez, C.F.3
  • 136
    • 0027285510 scopus 로고
    • GDNF: A glial cell line-derived neurotrophic factor for midbrain dopa- minergic neurons
    • Lin L. F.; Doherty D. H.; Lile J. D.; Bektesh S.; Collins F. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopa- minergic neurons. Science, 1993, 260(5111), 1130-1132.
    • (1993) Science , vol.260 , Issue.5111 , pp. 1130-1132
    • Lin, L.F.1    Doherty, D.H.2    Lile, J.D.3    Bektesh, S.4    Collins, F.5
  • 137
    • 0028109717 scopus 로고    scopus 로고
    • Henderson C. E.; Phillips H. S.; Pollock R. A.; Davies A. M.; Le-meulle C.; Armanini M.; Simmons L.; Moffet B.; Vandlen R. A.; Simpson LC [corrected to Simmons. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science, 1994, 266(5187), 1062-1064.
    • Henderson C. E.; Phillips H. S.; Pollock R. A.; Davies A. M.; Le-meulle C.; Armanini M.; Simmons L.; Moffet B.; Vandlen R. A.; Simpson LC [corrected to Simmons. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science, 1994, 266(5187), 1062-1064.
  • 138
    • 0030763998 scopus 로고    scopus 로고
    • Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population
    • Baumgartner B. J.; Shine H. D. Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factor genes confers neuroprotection that exceeds the transduced population. J. Neurosci., 1997, 17(17), 6504-6511.
    • (1997) J. Neurosci , vol.17 , Issue.17 , pp. 6504-6511
    • Baumgartner, B.J.1    Shine, H.D.2
  • 139
    • 4544293725 scopus 로고    scopus 로고
    • Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor
    • Blits B.; Carlstedt T. P.; Ruitenberg M. J.; de Winter F.; Hermens W. T.; Dijkhuizen P. A.; Claasens J. W.; Eggers R.; van der Sluis R.; Tenenbaum L.; Boer G. J.; Verhaagen J. Rescue and sprouting of motoneurons following ventral root avulsion and reimplantation combined with intraspinal adeno-associated viral vector-mediated expression of glial cell line-derived neurotrophic factor or brain-derived neurotrophic factor. Exp. Neurol., 2004, 189(2), 303-316.
    • (2004) Exp. Neurol , vol.189 , Issue.2 , pp. 303-316
    • Blits, B.1    Carlstedt, T.P.2    Ruitenberg, M.J.3    de Winter, F.4    Hermens, W.T.5    Dijkhuizen, P.A.6    Claasens, J.W.7    Eggers, R.8    van der Sluis, R.9    Tenenbaum, L.10    Boer, G.J.11    Verhaagen, J.12
  • 140
    • 0036460112 scopus 로고    scopus 로고
    • GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap
    • Fine E. G.; Decosterd I.; Papaloizos M.; Zurn A. D.; Aebischer P. GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap. Eur. J. Neurosci., 2002, 15(4), 589-601.
    • (2002) Eur. J. Neurosci , vol.15 , Issue.4 , pp. 589-601
    • Fine, E.G.1    Decosterd, I.2    Papaloizos, M.3    Zurn, A.D.4    Aebischer, P.5
  • 141
    • 0028822549 scopus 로고
    • Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor
    • Li L.; Wu W.; Lin L. F.; Lei M.; Oppenheim R. W.; Houenou L. J. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc. Natl. Acad. Sci. USA, 1995, 92(21), 9771-9775.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , Issue.21 , pp. 9771-9775
    • Li, L.1    Wu, W.2    Lin, L.F.3    Lei, M.4    Oppenheim, R.W.5    Houenou, L.J.6
  • 142
    • 33745493777 scopus 로고    scopus 로고
    • Survival of injured spinal motoneurons in adult rat upon treatment with glial cell line-derived neurotrophic factor at 2 weeks but not at 4 weeks after root avulsion
    • Zhou L. H.; Wu W. Survival of injured spinal motoneurons in adult rat upon treatment with glial cell line-derived neurotrophic factor at 2 weeks but not at 4 weeks after root avulsion. J. Neurotrauma, 2006, 23(6), 920-927.
    • (2006) J. Neurotrauma , vol.23 , Issue.6 , pp. 920-927
    • Zhou, L.H.1    Wu, W.2
  • 143
    • 2342498238 scopus 로고    scopus 로고
    • Co- treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury
    • Bergerot A.; Shortland P. J.; Anand P.; Hunt S. P.; Carlstedt T. Co- treatment with riluzole and GDNF is necessary for functional recovery after ventral root avulsion injury. Exp. Neurol., 2004, 187(2), 359-366.
    • (2004) Exp. Neurol , vol.187 , Issue.2 , pp. 359-366
    • Bergerot, A.1    Shortland, P.J.2    Anand, P.3    Hunt, S.P.4    Carlstedt, T.5
  • 145
    • 0026681212 scopus 로고
    • Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs
    • Streck R. D.; Wood T. L.; Hsu M. S.; Pintar J. E. Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs. Dev. Biol., 1992, 151(2), 586-596.
    • (1992) Dev. Biol , vol.151 , Issue.2 , pp. 586-596
    • Streck, R.D.1    Wood, T.L.2    Hsu, M.S.3    Pintar, J.E.4
  • 146
    • 0027527205 scopus 로고
    • Insulin-like growth factors: Putative muscle-derived trophic agents that promote motoneuron survival
    • Neff N. T.; Prevette D.; Houenou L. J.; Lewis M. E.; Glicksman M. A.; Yin Q. W.; Oppenheim R. W. Insulin-like growth factors: putative muscle-derived trophic agents that promote motoneuron survival. J. Neurobiol., 1993, 24(12), 1578-1588.
    • (1993) J. Neurobiol , vol.24 , Issue.12 , pp. 1578-1588
    • Neff, N.T.1    Prevette, D.2    Houenou, L.J.3    Lewis, M.E.4    Glicksman, M.A.5    Yin, Q.W.6    Oppenheim, R.W.7
  • 147
    • 0027254498 scopus 로고
    • Biological studies of a putative avian muscle-derived neurotrophic factor that prevents naturally occurring motoneuron death in vivo
    • Oppenheim R. W.; Prevette D.; Haverkamp L. J.; Houenou L.; Yin Q. W.; McManaman J. Biological studies of a putative avian muscle-derived neurotrophic factor that prevents naturally occurring motoneuron death in vivo. J. Neurobiol., 1993, 24(8), 1065-1079.
    • (1993) J. Neurobiol , vol.24 , Issue.8 , pp. 1065-1079
    • Oppenheim, R.W.1    Prevette, D.2    Haverkamp, L.J.3    Houenou, L.4    Yin, Q.W.5    McManaman, J.6
  • 148
    • 2942695980 scopus 로고    scopus 로고
    • IGF-I prevents glutamate-induced motor neuron programmed cell death
    • Vincent A. M.; Mobley B. C.; Hiller A.; Feldman E. L. IGF-I prevents glutamate-induced motor neuron programmed cell death. Neurobiol. Dis., 2004, 16(2), 407-416.
    • (2004) Neurobiol. Dis , vol.16 , Issue.2 , pp. 407-416
    • Vincent, A.M.1    Mobley, B.C.2    Hiller, A.3    Feldman, E.L.4
  • 149
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y.; Sendtner M.; Thoenen H. Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J. Neurosci., 1990, 10(11), 3507-3515.
    • (1990) J. Neurosci , vol.10 , Issue.11 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 150
    • 0026691620 scopus 로고
    • Effects of astrocytes, insulin and insulin-like growth factor I on the survival of motoneurons in vitro
    • Ang L. C.; Bhaumick B.; Munoz D. G.; Sass J.; Juurlink B. H. Effects of astrocytes, insulin and insulin-like growth factor I on the survival of motoneurons in vitro. J. Neurol. Sci., 1992, 109(2), 168-172.
    • (1992) J. Neurol. Sci , vol.109 , Issue.2 , pp. 168-172
    • Ang, L.C.1    Bhaumick, B.2    Munoz, D.G.3    Sass, J.4    Juurlink, B.H.5
  • 152
    • 0025234804 scopus 로고
    • Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors
    • Caroni P.; Grandes P. Nerve sprouting in innervated adult skeletal muscle induced by exposure to elevated levels of insulin-like growth factors. J. Cell Biol., 1990, 110(4), 1307-1317.
    • (1990) J. Cell Biol , vol.110 , Issue.4 , pp. 1307-1317
    • Caroni, P.1    Grandes, P.2
  • 153
    • 0027078550 scopus 로고
    • Insulin-like growth factor II stimulates motor nerve regeneration
    • Near S. L.; Whalen L. R.; Miller J. A.; Ishii D. N. Insulin-like growth factor II stimulates motor nerve regeneration. Proc. Natl. Acad. Sci. USA, 1992, 89(24), 11716-11720.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , Issue.24 , pp. 11716-11720
    • Near, S.L.1    Whalen, L.R.2    Miller, J.A.3    Ishii, D.N.4
  • 154
    • 0024391282 scopus 로고
    • Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve
    • Kanje M.; Skottner A.; Sjoberg J.; Lundborg G. Insulin-like growth factor I (IGF-I) stimulates regeneration of the rat sciatic nerve. Brain Res., 1989, 486(2), 396-398.
    • (1989) Brain Res , vol.486 , Issue.2 , pp. 396-398
    • Kanje, M.1    Skottner, A.2    Sjoberg, J.3    Lundborg, G.4
  • 155
    • 33750492639 scopus 로고    scopus 로고
    • IGF-I specifically enhances axon outgrowth of corticospinal motor neurons
    • Ozdinler P. H.; Macklis J. D. IGF-I specifically enhances axon outgrowth of corticospinal motor neurons. Nat. Neurosci., 2006, 9(11), 1371-1381.
    • (2006) Nat. Neurosci , vol.9 , Issue.11 , pp. 1371-1381
    • Ozdinler, P.H.1    Macklis, J.D.2
  • 156
    • 0038203257 scopus 로고    scopus 로고
    • Rescue of rat spinal motoneurons from avulsion-induced cell death by intrathecal administration of IGF-I and Cerebrolysin
    • Haninec P.; Houst'ava L.; Stejskal L.; Dubovy P. Rescue of rat spinal motoneurons from avulsion-induced cell death by intrathecal administration of IGF-I and Cerebrolysin. Ann. Anat., 2003, 185(3), 233-238.
    • (2003) Ann. Anat , vol.185 , Issue.3 , pp. 233-238
    • Haninec, P.1    Houst'ava, L.2    Stejskal, L.3    Dubovy, P.4
  • 157
    • 0035081241 scopus 로고    scopus 로고
    • Fibroblast growth factors
    • REVIEWS3005
    • Ornitz D. M.; Itoh N. Fibroblast growth factors. Genome Biol., 2001, 2(3), REVIEWS3005-.
    • (2001) Genome Biol , vol.2 , Issue.3
    • Ornitz, D.M.1    Itoh, N.2
  • 158
    • 4744372082 scopus 로고    scopus 로고
    • Evolution of the Fgf and Fgfr gene families
    • Itoh N.; Ornitz D. M. Evolution of the Fgf and Fgfr gene families. Trends Genet., 2004, 20(11), 563-569.
    • (2004) Trends Genet , vol.20 , Issue.11 , pp. 563-569
    • Itoh, N.1    Ornitz, D.M.2
  • 159
    • 29144480242 scopus 로고    scopus 로고
    • Differentially promoted peripheral nerve regeneration by grafted Schwann cells over-expressing different FGF-2 isoforms
    • Haastert K.; Lipokatic E.; Fischer M.; Timmer M.; Grothe C. Differentially promoted peripheral nerve regeneration by grafted Schwann cells over-expressing different FGF-2 isoforms. Neurobiol. Dis., 2006, 27(1), 138-153.
    • (2006) Neurobiol. Dis , vol.27 , Issue.1 , pp. 138-153
    • Haastert, K.1    Lipokatic, E.2    Fischer, M.3    Timmer, M.4    Grothe, C.5
  • 160
    • 0023928594 scopus 로고
    • Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo
    • Anderson K. J.; Dam D.; Lee S.; Cotman C. W. Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo. Nature, 1988, 332(6162), 360-361.
    • (1988) Nature , vol.332 , Issue.6162 , pp. 360-361
    • Anderson, K.J.1    Dam, D.2    Lee, S.3    Cotman, C.W.4
  • 161
    • 0031844746 scopus 로고    scopus 로고
    • Basic and acidic fibroblast growth factors protect spinal motor neurones in vivo after experimental spinal cord injury
    • Teng Y. D.; Mocchetti I.; Wrathall J. R. Basic and acidic fibroblast growth factors protect spinal motor neurones in vivo after experimental spinal cord injury. Eur. J. Neurosci., 1998, 10(2).
    • (1998) Eur. J. Neurosci , vol.10 , Issue.2
    • Teng, Y.D.1    Mocchetti, I.2    Wrathall, J.R.3
  • 162
    • 0006495387 scopus 로고    scopus 로고
    • D.; Mocchetti I.; Taveira-DaSilva A. M.; Gillis R. A.; Wrathall J. R. Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury. J. Neurosci., 1999, 19(16), 7037-7047.
    • D.; Mocchetti I.; Taveira-DaSilva A. M.; Gillis R. A.; Wrathall J. R. Basic fibroblast growth factor increases long-term survival of spinal motor neurons and improves respiratory function after experimental spinal cord injury. J. Neurosci., 1999, 19(16), 7037-7047.
  • 163
    • 0008563256 scopus 로고
    • Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons
    • Florkiewicz R. Z.; Sommer A. Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons. Proc. Natl. Acad. Sci. USA, 1989, 86(11), 3978-3981.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , Issue.11 , pp. 3978-3981
    • Florkiewicz, R.Z.1    Sommer, A.2
  • 164
    • 0031016932 scopus 로고    scopus 로고
    • Differential regulation of fibroblast growth factor (FGF)-2 and FGF receptor 1 mRNAs and FGF-2 isoforms in spinal ganglia and sciatic nerve after peripheral nerve lesion
    • Meisinger C.; Grothe C. Differential regulation of fibroblast growth factor (FGF)-2 and FGF receptor 1 mRNAs and FGF-2 isoforms in spinal ganglia and sciatic nerve after peripheral nerve lesion. J. Neurochem., 1997, 68(3), 1150-1158.
    • (1997) J. Neurochem , vol.68 , Issue.3 , pp. 1150-1158
    • Meisinger, C.1    Grothe, C.2
  • 165
    • 0031906182 scopus 로고    scopus 로고
    • Regulatory effects of trophic factors on expression and distribution of CGRP and GAP-43 in rat motoneurons
    • Piehl F.; Hammarberg H.; Hokfelt T.; Cullheim S. Regulatory effects of trophic factors on expression and distribution of CGRP and GAP-43 in rat motoneurons. J. Neurosci. Res., 1998, 51(1), 1-14.
    • (1998) J. Neurosci. Res , vol.51 , Issue.1 , pp. 1-14
    • Piehl, F.1    Hammarberg, H.2    Hokfelt, T.3    Cullheim, S.4
  • 166
    • 0029964577 scopus 로고    scopus 로고
    • Transforming growth factor-beta 3, glial cell line-derived neurotrophic factor, and fibroblast growth factor-2, act in different manners to promote motoneuron survival in vitro
    • Gouin A.; Bloch-Gallego E.; Tanaka H.; Rosenthal A.; Henderson C. E. Transforming growth factor-beta 3, glial cell line-derived neurotrophic factor, and fibroblast growth factor-2, act in different manners to promote motoneuron survival in vitro. J. Neurosci. Res., 1996, 43(4), 454-464.
    • (1996) J. Neurosci. Res , vol.43 , Issue.4 , pp. 454-464
    • Gouin, A.1    Bloch-Gallego, E.2    Tanaka, H.3    Rosenthal, A.4    Henderson, C.E.5
  • 168
    • 1942423576 scopus 로고    scopus 로고
    • Astrocytic production of nerve growth factor in motor neuron apoptosis: Implications for amyotrophic lateral sclerosis
    • Pehar M.; Cassina P.; Vargas M. R.; Castellanos R.; Viera L.; Beckman J. S.; Estevez A. G.; Barbeito L. Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. J. Neurochem., 2004, 89(2), 464-473.
    • (2004) J. Neurochem , vol.89 , Issue.2 , pp. 464-473
    • Pehar, M.1    Cassina, P.2    Vargas, M.R.3    Castellanos, R.4    Viera, L.5    Beckman, J.S.6    Estevez, A.G.7    Barbeito, L.8
  • 169
    • 21844474290 scopus 로고    scopus 로고
    • Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: Consequences for motor neuron survival
    • Vargas M. R.; Pehar M.; Cassina P.; Martinez-Palma L.; Thompson J. A.; Beckman J. S.; Barbeito L. Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. J. Biol. Chem., 2005, 280(27), 25571-25579.
    • (2005) J. Biol. Chem , vol.280 , Issue.27 , pp. 25571-25579
    • Vargas, M.R.1    Pehar, M.2    Cassina, P.3    Martinez-Palma, L.4    Thompson, J.A.5    Beckman, J.S.6    Barbeito, L.7
  • 170
    • 0035836698 scopus 로고    scopus 로고
    • An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
    • Chan K.; Han X. D.; Kan Y. W. An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen. Proc. Natl. Acad. Sci. USA, 2001, 98(8), 4611-4616.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , Issue.8 , pp. 4611-4616
    • Chan, K.1    Han, X.D.2    Kan, Y.W.3
  • 171
    • 13044304201 scopus 로고    scopus 로고
    • Nrf2 is essential for protection against acute pulmonary injury in mice
    • Chan K.; Kan Y. W. Nrf2 is essential for protection against acute pulmonary injury in mice. Proc. Natl. Acad. Sci. USA, 1999, 96(22), 12731-12736.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , Issue.22 , pp. 12731-12736
    • Chan, K.1    Kan, Y.W.2
  • 172
    • 0028835748 scopus 로고
    • Acidic fibroblast growth factor stimulates motor and sensory axon regeneration after sciatic nerve crush in the rat
    • Laird J. M.; Mason G. S.; Thomas K. A.; Hargreaves R. J.; Hill R. G. Acidic fibroblast growth factor stimulates motor and sensory axon regeneration after sciatic nerve crush in the rat. Neuroscience, 1995, 65(1), 209-216.
    • (1995) Neuroscience , vol.65 , Issue.1 , pp. 209-216
    • Laird, J.M.1    Mason, G.S.2    Thomas, K.A.3    Hargreaves, R.J.4    Hill, R.G.5
  • 173
    • 0344838674 scopus 로고    scopus 로고
    • Cervical root repair in adult rats after transection: Recovery of forelimb motor function
    • Huang M. C.; Chen K. C.; Chuang T. Y.; Chang W. C.; Lee L. S.; Huang W. C.; Cheng H. Cervical root repair in adult rats after transection: recovery of forelimb motor function. Exp. Neurol., 2003, 180(2), 101-109.
    • (2003) Exp. Neurol , vol.180 , Issue.2 , pp. 101-109
    • Huang, M.C.1    Chen, K.C.2    Chuang, T.Y.3    Chang, W.C.4    Lee, L.S.5    Huang, W.C.6    Cheng, H.7
  • 174
    • 23944477399 scopus 로고    scopus 로고
    • Spinal cord implantation with acidic fibroblast growth factor as a treatment for root avulsion in obstetric brachial plexus palsy
    • Lin P. H.; Cheng H.; Huang W. C.; Chuang T. Y. Spinal cord implantation with acidic fibroblast growth factor as a treatment for root avulsion in obstetric brachial plexus palsy. J. Chin Med. Assoc., 2005, 68(8), 392-396.
    • (2005) J. Chin Med. Assoc , vol.68 , Issue.8 , pp. 392-396
    • Lin, P.H.1    Cheng, H.2    Huang, W.C.3    Chuang, T.Y.4
  • 176
    • 0023661693 scopus 로고
    • Scatter factor is a fibroblast-derived modulator of epithelial cell mobility
    • Stoker M.; Gherardi E.; Perryman M.; Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature, 1987, 327(6119), 239-242.
    • (1987) Nature , vol.327 , Issue.6119 , pp. 239-242
    • Stoker, M.1    Gherardi, E.2    Perryman, M.3    Gray, J.4
  • 177
    • 0032189977 scopus 로고    scopus 로고
    • Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase
    • Birchmeier C.; Gherardi E. Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol., 1998, 8(10), 404-410.
    • (1998) Trends Cell Biol , vol.8 , Issue.10 , pp. 404-410
    • Birchmeier, C.1    Gherardi, E.2
  • 178
    • 0031590435 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration
    • Matsumoto K.; Nakamura T. Hepatocyte growth factor (HGF) as a tissue organizer for organogenesis and regeneration. Biochem. Biophys. Res. Commun., 1997, 239(3), 639-644.
    • (1997) Biochem. Biophys. Res. Commun , vol.239 , Issue.3 , pp. 639-644
    • Matsumoto, K.1    Nakamura, T.2
  • 179
    • 0033362351 scopus 로고    scopus 로고
    • Hepatocyte growth factor, a versatile signal for developing neurons
    • Maina F.; Klein R. Hepatocyte growth factor, a versatile signal for developing neurons. Nat. Neurosci., 1999, 2(3), 213-217.
    • (1999) Nat. Neurosci , vol.2 , Issue.3 , pp. 213-217
    • Maina, F.1    Klein, R.2
  • 180
    • 0029985372 scopus 로고    scopus 로고
    • Emerging multipotent aspects of hepatocyte growth factor
    • Matsumoto K.; Nakamura T. Emerging multipotent aspects of hepatocyte growth factor. J. Biochem., 1996, 119(4), 591-600.
    • (1996) J. Biochem , vol.119 , Issue.4 , pp. 591-600
    • Matsumoto, K.1    Nakamura, T.2
  • 181
    • 0028308229 scopus 로고
    • Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain
    • Jung W.; Castren E.; Odenthal M.; Vande Woude G. F.; Ishii T.; Dienes H. P.; Lindholm D.; Schirmacher P. Expression and functional interaction of hepatocyte growth factor-scatter factor and its receptor c-met in mammalian brain. J. Cell Biol., 1994, 126(2), 485-494.
    • (1994) J. Cell Biol , vol.126 , Issue.2 , pp. 485-494
    • Jung, W.1    Castren, E.2    Odenthal, M.3    Vande Woude, G.F.4    Ishii, T.5    Dienes, H.P.6    Lindholm, D.7    Schirmacher, P.8
  • 183
    • 0031046192 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes motor neuron survival and synergizes with ciliary neurotrophic factor
    • Wong V.; Glass D. J.; Arriaga R.; Yancopoulos G. D.; Lindsay R. M.; Conn G. Hepatocyte growth factor promotes motor neuron survival and synergizes with ciliary neurotrophic factor. J. Biol. Chem., 1997, 272(8), 5187-5191.
    • (1997) J. Biol. Chem , vol.272 , Issue.8 , pp. 5187-5191
    • Wong, V.1    Glass, D.J.2    Arriaga, R.3    Yancopoulos, G.D.4    Lindsay, R.M.5    Conn, G.6
  • 184
    • 0001517943 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons
    • Ebens A.; Brose K.; Leonardo E. D.; Hanson M. G. Jr.; Bladt F.; Birchmeier C.; Barres B. A.; Tessier-Lavigne M. Hepatocyte growth factor/scatter factor is an axonal chemoattractant and a neurotrophic factor for spinal motor neurons. Neuron, 1996, 17(6), 1157-1172.
    • (1996) Neuron , vol.17 , Issue.6 , pp. 1157-1172
    • Ebens, A.1    Brose, K.2    Leonardo, E.D.3    Hanson Jr., M.G.4    Bladt, F.5    Birchmeier, C.6    Barres, B.A.7    Tessier-Lavigne, M.8
  • 185
    • 0033999093 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo
    • Novak K. D.; Prevette D.; Wang S.; Gould T. W.; Oppenheim R. W. Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo. J. Neurosci., 2000, 20(1), 326-337.
    • (2000) J. Neurosci , vol.20 , Issue.1 , pp. 326-337
    • Novak, K.D.1    Prevette, D.2    Wang, S.3    Gould, T.W.4    Oppenheim, R.W.5
  • 186
    • 0030865088 scopus 로고    scopus 로고
    • Yamamoto Y.; Livet J.; Pollock R. A.; Garces A.; Arce V.; de- Lapeyriere O.; Henderson C. E. Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. Development, 1997, 124(15), 2903-2913.
    • Yamamoto Y.; Livet J.; Pollock R. A.; Garces A.; Arce V.; de- Lapeyriere O.; Henderson C. E. Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. Development, 1997, 124(15), 2903-2913.
  • 188
    • 0036703771 scopus 로고    scopus 로고
    • Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS
    • Sun W.; Funakoshi H.; Nakamura T. Overexpression of HGF retards disease progression and prolongs life span in a transgenic mouse model of ALS. J. Neurosci., 2002, 22(15), 6537-6548.
    • (2002) J. Neurosci , vol.22 , Issue.15 , pp. 6537-6548
    • Sun, W.1    Funakoshi, H.2    Nakamura, T.3
  • 191
    • 0025937855 scopus 로고
    • Purification and cloning of vascular endothelial growth factor secreted by pituitary folliculostellate cells
    • Ferrara N.; Leung D. W.; Cachianes G.; Winer J.; Henzel W. J. Purification and cloning of vascular endothelial growth factor secreted by pituitary folliculostellate cells. Methods Enzymol., 1991, 198, 391-405.
    • (1991) Methods Enzymol , vol.198 , pp. 391-405
    • Ferrara, N.1    Leung, D.W.2    Cachianes, G.3    Winer, J.4    Henzel, W.J.5
  • 192
    • 0024384470 scopus 로고
    • Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells
    • Ferrara N.; Henzel W. J. Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells. Biochem. Biophys. Res. Commun., 1989, 161(2), 851-858.
    • (1989) Biochem. Biophys. Res. Commun , vol.161 , Issue.2 , pp. 851-858
    • Ferrara, N.1    Henzel, W.J.2
  • 193
    • 0025646089 scopus 로고
    • Conditioned medium from mouse sarcoma 180 cells contains vascular endothelial growth factor
    • Rosenthal R. A.; Megyesi J. F.; Henzel W. J.; Ferrara N.; Folkman J. Conditioned medium from mouse sarcoma 180 cells contains vascular endothelial growth factor. Growth Factors, 1990, 4(1), 53-59.
    • (1990) Growth Factors , vol.4 , Issue.1 , pp. 53-59
    • Rosenthal, R.A.1    Megyesi, J.F.2    Henzel, W.J.3    Ferrara, N.4    Folkman, J.5
  • 194
    • 3142781388 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and other signaling pathways in developmental and pathologic angiogenesis
    • Thurston G.; Gale N. W. Vascular endothelial growth factor and other signaling pathways in developmental and pathologic angiogenesis. Int. J. Hematol., 2004, 80(1), 7-20.
    • (2004) Int. J. Hematol , vol.80 , Issue.1 , pp. 7-20
    • Thurston, G.1    Gale, N.W.2
  • 195
    • 0000481740 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: Direct neuroprotective effect in in vitro ischemia
    • Jin K. L.; Mao X. O.; Greenberg D. A. Vascular endothelial growth factor: direct neuroprotective effect in in vitro ischemia. Proc. Natl. Acad. Sci. USA, 2000, 97(18), 10242-10247.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.18 , pp. 10242-10247
    • Jin, K.L.1    Mao, X.O.2    Greenberg, D.A.3
  • 200
    • 0031419189 scopus 로고    scopus 로고
    • VEGF mRNA induction correlates with changes in the vascular architecture upon spinal cord damage in the rat
    • Bartholdi D.; Rubin B. P.; Schwab M. E. VEGF mRNA induction correlates with changes in the vascular architecture upon spinal cord damage in the rat. Eur. J. Neurosci., 1997, 9(12), 2549-2560.
    • (1997) Eur. J. Neurosci , vol.9 , Issue.12 , pp. 2549-2560
    • Bartholdi, D.1    Rubin, B.P.2    Schwab, M.E.3
  • 201
    • 0033788609 scopus 로고    scopus 로고
    • Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration
    • Skold M.; Cullheim S.; Hammarberg H.; Piehl F.; Suneson A.; Lake S.; Sjogren A.; Walum E.; Risling M. Induction of VEGF and VEGF receptors in the spinal cord after mechanical spinal injury and prostaglandin administration. Eur. J. Neurosci., 2000, 12(10), 3675-3686.
    • (2000) Eur. J. Neurosci , vol.12 , Issue.10 , pp. 3675-3686
    • Skold, M.1    Cullheim, S.2    Hammarberg, H.3    Piehl, F.4    Suneson, A.5    Lake, S.6    Sjogren, A.7    Walum, E.8    Risling, M.9
  • 202
    • 0036829006 scopus 로고    scopus 로고
    • Neurotrophins: From enthusiastic expectations through sobering experiences to rational therapeutic approaches
    • Thoenen H.; Sendtner M. Neurotrophins: from enthusiastic expectations through sobering experiences to rational therapeutic approaches. Nat. Neurosci., 2002, 5 (Suppl), 1046-1050.
    • (2002) Nat. Neurosci , vol.5 , Issue.SUPPL. , pp. 1046-1050
    • Thoenen, H.1    Sendtner, M.2
  • 203
    • 0034978562 scopus 로고    scopus 로고
    • Oosthuyse B.; Moons L.; Storkebaum E.; Beck H.; Nuyens D.; Brusselmans K.; Van Dorpe J.; Hellings P.; Gorselink M.; Heymans S.; Theilmeier G.; Dewerchin M.; Laudenbach V.; Vermylen P.; Raat H.; Acker T.; Vleminckx V.; Van Den Bosch L.; Cashman N.; Fujisawa H.; Drost M. R.; Sciot R.; Bruyninckx F.; Hicklin D. J.; Ince C.; Gressens P.; Lupu F.; Plate K. H.; Robberecht W.; Herbert J. M.; Collen D.; Carmeliet P. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat. Genet., 2001, 28(2), 131-138.
    • Oosthuyse B.; Moons L.; Storkebaum E.; Beck H.; Nuyens D.; Brusselmans K.; Van Dorpe J.; Hellings P.; Gorselink M.; Heymans S.; Theilmeier G.; Dewerchin M.; Laudenbach V.; Vermylen P.; Raat H.; Acker T.; Vleminckx V.; Van Den Bosch L.; Cashman N.; Fujisawa H.; Drost M. R.; Sciot R.; Bruyninckx F.; Hicklin D. J.; Ince C.; Gressens P.; Lupu F.; Plate K. H.; Robberecht W.; Herbert J. M.; Collen D.; Carmeliet P. Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration. Nat. Genet., 2001, 28(2), 131-138.
  • 204
    • 0041903805 scopus 로고    scopus 로고
    • Lambrechts D.; Storkebaum E.; Morimoto M.; Del-Favero J.; Desmet F.; Marklund S. L.; Wyns S.; Thijs V.; Andersson J.; van Marion, I; Al-Chalabi A.; Bornes S.; Musson R.; Hansen V.; Beckman L.; Adolfsson R.; Pall H. S.; Prats H.; Vermeire S.; Rut- geerts P.; Katayama S.; Awata T.; Leigh N.; Lang-Lazdunski L.; Dewerchin M.; Shaw C.; Moons L.; Vlietinck R.; Morrison K. E.; Robberecht W.; Van Broeckhoven C.; Collen D.; Andersen P. M.; Carmeliet P. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat. Genet., 2003, 34(4), 383-394.
    • Lambrechts D.; Storkebaum E.; Morimoto M.; Del-Favero J.; Desmet F.; Marklund S. L.; Wyns S.; Thijs V.; Andersson J.; van Marion, I; Al-Chalabi A.; Bornes S.; Musson R.; Hansen V.; Beckman L.; Adolfsson R.; Pall H. S.; Prats H.; Vermeire S.; Rut- geerts P.; Katayama S.; Awata T.; Leigh N.; Lang-Lazdunski L.; Dewerchin M.; Shaw C.; Moons L.; Vlietinck R.; Morrison K. E.; Robberecht W.; Van Broeckhoven C.; Collen D.; Andersen P. M.; Carmeliet P. VEGF is a modifier of amyotrophic lateral sclerosis in mice and humans and protects motoneurons against ischemic death. Nat. Genet., 2003, 34(4), 383-394.
  • 205
    • 42549127816 scopus 로고    scopus 로고
    • Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase
    • Tolosa L.; Mir M.; Asensio V. J.; Olmos G.; Llado J. Vascular endothelial growth factor protects spinal cord motoneurons against glutamate-induced excitotoxicity via phosphatidylinositol 3-kinase. J. Neurochem., 2008; 105(4),1080-90.
    • (2008) J. Neurochem , vol.105 , Issue.4 , pp. 1080-1090
    • Tolosa, L.1    Mir, M.2    Asensio, V.J.3    Olmos, G.4    Llado, J.5
  • 206
    • 33749385489 scopus 로고    scopus 로고
    • Vascular endothelial growth factor in amyotrophic lateral sclerosis and other neurodegenerative diseases
    • Bogaert E.; Van Damme P.; Van Den Bosch L.; Robberecht W. Vascular endothelial growth factor in amyotrophic lateral sclerosis and other neurodegenerative diseases. Muscle Nerve, 2006, 34(4), 391-405.
    • (2006) Muscle Nerve , vol.34 , Issue.4 , pp. 391-405
    • Bogaert, E.1    Van Damme, P.2    Van Den Bosch, L.3    Robberecht, W.4
  • 207
    • 0034526311 scopus 로고    scopus 로고
    • VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy
    • Hobson M. I.; Green C. J.; Terenghi G. VEGF enhances intraneural angiogenesis and improves nerve regeneration after axotomy. J. Anat., 2000, 197 (Pt 4), 591-605.
    • (2000) J. Anat , vol.197 , Issue.PART 4 , pp. 591-605
    • Hobson, M.I.1    Green, C.J.2    Terenghi, G.3
  • 209
    • 0027446940 scopus 로고
    • Pigment epithelium-derived factor: Neurotrophic activity and identification as a member of the serine protease inhibitor gene family
    • Steele F. R.; Chader G. J.; Johnson L. V.; Tombran-Tink J. Pigment epithelium-derived factor: neurotrophic activity and identification as a member of the serine protease inhibitor gene family. Proc. Natl. Acad. Sci. USA, 1993, 90(4), 1526-1530.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , Issue.4 , pp. 1526-1530
    • Steele, F.R.1    Chader, G.J.2    Johnson, L.V.3    Tombran-Tink, J.4
  • 210
    • 0025772716 scopus 로고
    • PEDF: A pigment epithelium-derived factor with potent neuronal differentiative activity
    • Tombran-Tink J.; Chader G. G.; Johnson L. V. PEDF: a pigment epithelium-derived factor with potent neuronal differentiative activity. Exp. Eye Res., 1991, 53(3), 411-414.
    • (1991) Exp. Eye Res , vol.53 , Issue.3 , pp. 411-414
    • Tombran-Tink, J.1    Chader, G.G.2    Johnson, L.V.3
  • 211
    • 0024394207 scopus 로고
    • Neuronal differentiation of retino-blastoma cells induced by medium conditioned by human RPE cells
    • Tombran-Tink J.; Johnson L. V. Neuronal differentiation of retino-blastoma cells induced by medium conditioned by human RPE cells. Invest. Ophthalmol. Vis. Sci., 1989, 30(8), 1700-1707.
    • (1989) Invest. Ophthalmol. Vis. Sci , vol.30 , Issue.8 , pp. 1700-1707
    • Tombran-Tink, J.1    Johnson, L.V.2
  • 212
    • 0020689778 scopus 로고
    • Inhibition of protease activity can lead to neurite extension in neuroblastoma cells
    • Monard D.; Niday E.; Limat A.; Solomon F. Inhibition of protease activity can lead to neurite extension in neuroblastoma cells. Prog. Brain Res., 1983, 58359-364.
    • (1983) Prog. Brain Res , vol.58 , pp. 359-364
    • Monard, D.1    Niday, E.2    Limat, A.3    Solomon, F.4
  • 213
    • 0028800603 scopus 로고
    • A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death
    • Houenou L. J.; Turner P. L.; Li L.; Oppenheim R. W.; Festoff B. W. A serine protease inhibitor, protease nexin I, rescues motoneurons from naturally occurring and axotomy-induced cell death.P roc. Natl. Acad. Sci. USA, 1995, 92(3), 895-899.
    • (1995) P roc. Natl. Acad. Sci. USA , vol.92 , Issue.3 , pp. 895-899
    • Houenou, L.J.1    Turner, P.L.2    Li, L.3    Oppenheim, R.W.4    Festoff, B.W.5
  • 214
    • 0029948143 scopus 로고    scopus 로고
    • Prevention of activity-dependent neuronal death: Vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin, protease nexin I
    • Festoff B. W.; Nelson P. G.; Brenneman D. E. Prevention of activity-dependent neuronal death: vasoactive intestinal polypeptide stimulates astrocytes to secrete the thrombin-inhibiting neurotrophic serpin, protease nexin I. J. Neurobiol., 1996, 30(2), 255-266.
    • (1996) J. Neurobiol , vol.30 , Issue.2 , pp. 255-266
    • Festoff, B.W.1    Nelson, P.G.2    Brenneman, D.E.3
  • 215
    • 0030569057 scopus 로고    scopus 로고
    • Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin
    • Tombran-Tink J.; Mazuruk K.; Rodriguez I. R.; Chung D.; Linker T.; Englander E.; Chader G. J. Organization, evolutionary conservation, expression and unusual Alu density of the human gene for pigment epithelium-derived factor, a unique neurotrophic serpin. Mol. Vis., 1996; 4, 2-11.
    • (1996) Mol. Vis , vol.4 , pp. 2-11
    • Tombran-Tink, J.1    Mazuruk, K.2    Rodriguez, I.R.3    Chung, D.4    Linker, T.5    Englander, E.6    Chader, G.J.7
  • 216
    • 0042737443 scopus 로고    scopus 로고
    • PEDF: A multifaceted neurotro- phic factor
    • Tombran-Tink J.; Barnstable C. J. PEDF: a multifaceted neurotro- phic factor. Nat. Rev. Neurosci., 2003, 4(8), 628-636.
    • (2003) Nat. Rev. Neurosci , vol.4 , Issue.8 , pp. 628-636
    • Tombran-Tink, J.1    Barnstable, C.J.2
  • 217
    • 0032796456 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration
    • Bilak M. M.; Corse A. M.; Bilak S. R.; Lehar M.; Tombran-Tink J.; Kuncl R. W. Pigment epithelium-derived factor (PEDF) protects motor neurons from chronic glutamate-mediated neurodegeneration. J. Neuropathol. Exp. Neurol., 1999, 58(7), 719-728.
    • (1999) J. Neuropathol. Exp. Neurol , vol.58 , Issue.7 , pp. 719-728
    • Bilak, M.M.1    Corse, A.M.2    Bilak, S.R.3    Lehar, M.4    Tombran-Tink, J.5    Kuncl, R.W.6
  • 218
    • 0033610224 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons
    • Houenou L. J.; D'Costa A. P.; Li L.; Turgeon V. L.; Enyadike C.; Alberdi E.; Becerra S. P. Pigment epithelium-derived factor promotes the survival and differentiation of developing spinal motor neurons. J. Comp. Neurol., 1999, 412(3), 506-514.
    • (1999) J. Comp. Neurol , vol.412 , Issue.3 , pp. 506-514
    • Houenou, L.J.1    D'Costa, A.P.2    Li, L.3    Turgeon, V.L.4    Enyadike, C.5    Alberdi, E.6    Becerra, S.P.7
  • 219
    • 0036074844 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor is elevated in CSF of patients with amyotrophic lateral sclerosis
    • Kuncl R. W.; Bilak M. M.; Bilak S. R.; Corse A. M.; Royal W.; Becerra S. P. Pigment epithelium-derived factor is elevated in CSF of patients with amyotrophic lateral sclerosis. J. Neurochem., 2002, 81(1), 178-184.
    • (2002) J. Neurochem , vol.81 , Issue.1 , pp. 178-184
    • Kuncl, R.W.1    Bilak, M.M.2    Bilak, S.R.3    Corse, A.M.4    Royal, W.5    Becerra, S.P.6
  • 220
    • 0036849639 scopus 로고    scopus 로고
    • Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons
    • Bilak M. M.; Becerra S. P.; Vincent A. M.; Moss B. H.; Aymerich M. S.; Kuncl R. W. Identification of the neuroprotective molecular region of pigment epithelium-derived factor and its binding sites on motor neurons. J. Neurosci., 2002, 22(21), 9378-9386.
    • (2002) J. Neurosci , vol.22 , Issue.21 , pp. 9378-9386
    • Bilak, M.M.1    Becerra, S.P.2    Vincent, A.M.3    Moss, B.H.4    Aymerich, M.S.5    Kuncl, R.W.6
  • 221
    • 0025615372 scopus 로고
    • Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity
    • Li Y. S.; Milner P. G.; Chauhan A. K.; Watson M. A.; Hoffman R. M.; Kodner C. M.; Milbrandt J.; Deuel T. F. Cloning and expression of a developmentally regulated protein that induces mitogenic and neurite outgrowth activity. Science, 1990, 250(4988), 1690-1694.
    • (1990) Science , vol.250 , Issue.4988 , pp. 1690-1694
    • Li, Y.S.1    Milner, P.G.2    Chauhan, A.K.3    Watson, M.A.4    Hoffman, R.M.5    Kodner, C.M.6    Milbrandt, J.7    Deuel, T.F.8
  • 223
    • 0024317792 scopus 로고    scopus 로고
    • Rauvala H. An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J., 1989, 8(10), 2933-2941.
    • Rauvala H. An 18-kd heparin-binding protein of developing brain that is distinct from fibroblast growth factors. EMBO J., 1989, 8(10), 2933-2941.
  • 224
    • 37549023012 scopus 로고    scopus 로고
    • Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts
    • Perez-Pinera P.; Chang Y.; Deuel T. F. Pleiotrophin, a multifunctional tumor promoter through induction of tumor angiogenesis, remodeling of the tumor microenvironment, and activation of stromal fibroblasts. Cell Cycle, 2007, 6(23), 2877-2883.
    • (2007) Cell Cycle , vol.6 , Issue.23 , pp. 2877-2883
    • Perez-Pinera, P.1    Chang, Y.2    Deuel, T.F.3
  • 225
    • 0036739307 scopus 로고    scopus 로고
    • Midkine and pleiotrophin: Two related proteins involved in development, survival, inflammation and tumorigenesis
    • Muramatsu T. Midkine and pleiotrophin: two related proteins involved in development, survival, inflammation and tumorigenesis. J. Biochem., 2002, 132(3), 359-371.
    • (2002) J. Biochem , vol.132 , Issue.3 , pp. 359-371
    • Muramatsu, T.1
  • 226
    • 34248329194 scopus 로고    scopus 로고
    • Pleiotrophin is a neurotrophic factor for spinal motor neurons
    • Mi R.; Chen W.; Hoke A. Pleiotrophin is a neurotrophic factor for spinal motor neurons. Proc. Natl. Acad. Sci. USA, 2007, 104(11), 4664-4669.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , Issue.11 , pp. 4664-4669
    • Mi, R.1    Chen, W.2    Hoke, A.3
  • 227
    • 22944465060 scopus 로고    scopus 로고
    • Pleiotrophin cellular localization in nerve regeneration after peripheral nerve injury
    • Blondet B.; Carpentier G.; Lafdil F.; Courty J. Pleiotrophin cellular localization in nerve regeneration after peripheral nerve injury. J. Histochem. Cytochem., 2005, 53(8), 971-977.
    • (2005) J. Histochem. Cytochem , vol.53 , Issue.8 , pp. 971-977
    • Blondet, B.1    Carpentier, G.2    Lafdil, F.3    Courty, J.4
  • 228
    • 0034646459 scopus 로고    scopus 로고
    • Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta
    • Meng K.; Rodriguez-Pena A.; Dimitrov T.; Chen W.; Yamin M.; Noda M.; Deuel T. F. Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta. Proc. Natl. Acad. Sci. USA, 2000, 97(6), 2603-2608.
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , Issue.6 , pp. 2603-2608
    • Meng, K.1    Rodriguez-Pena, A.2    Dimitrov, T.3    Chen, W.4    Yamin, M.5    Noda, M.6    Deuel, T.F.7
  • 229
    • 0028216755 scopus 로고
    • Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3)
    • Raulo E.; Chernousov M. A.; Carey D. J.; Nolo R.; Rauvala H. Isolation of a neuronal cell surface receptor of heparin binding growth-associated molecule (HB-GAM). Identification as N-syndecan (syndecan-3). J. Biol. Chem., 1994, 269(17), 12999-13004.
    • (1994) J. Biol. Chem , vol.269 , Issue.17 , pp. 12999-13004
    • Raulo, E.1    Chernousov, M.A.2    Carey, D.J.3    Nolo, R.4    Rauvala, H.5
  • 232
    • 0347984998 scopus 로고    scopus 로고
    • Experimental strategies to promote functional recovery after peripheral nerve injuries
    • Gordon T.; Sulaiman O.; Boyd J. G. Experimental strategies to promote functional recovery after peripheral nerve injuries. J. Peripher. Nerv. Syst., 2003, 8(4), 236-250.
    • (2003) J. Peripher. Nerv. Syst , vol.8 , Issue.4 , pp. 236-250
    • Gordon, T.1    Sulaiman, O.2    Boyd, J.G.3
  • 233
    • 0036144945 scopus 로고    scopus 로고
    • Hoke A.; Gordon T.; Zochodne D. W.; Sulaiman O. A. A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation. Exp. Neurol., 2002, 173(1), 77-85.
    • Hoke A.; Gordon T.; Zochodne D. W.; Sulaiman O. A. A decline in glial cell-line-derived neurotrophic factor expression is associated with impaired regeneration after long-term Schwann cell denervation. Exp. Neurol., 2002, 173(1), 77-85.
  • 234
    • 33845288983 scopus 로고    scopus 로고
    • Delayed riluzole treatment is able to rescue injured rat spinal motoneurons
    • Nogradi A.; Szabo A.; Pinter S.; Vrbova G. Delayed riluzole treatment is able to rescue injured rat spinal motoneurons. Neuroscience, 2007, 144(2), 431-438.
    • (2007) Neuroscience , vol.144 , Issue.2 , pp. 431-438
    • Nogradi, A.1    Szabo, A.2    Pinter, S.3    Vrbova, G.4
  • 236
    • 33746932893 scopus 로고    scopus 로고
    • Gene delivery to the spinal cord: Comparison between lentiviral, adenoviral, and retroviral vector delivery systems
    • Abdellatif A. A.; Pelt J. L.; Benton R. L.; Howard R. M.; Tsoulfas P.; Ping P.; Xu X. M.; Whittemore S. R. Gene delivery to the spinal cord: comparison between lentiviral, adenoviral, and retroviral vector delivery systems. J. Neurosci. Res., 2006, 84(3), 553-567.
    • (2006) J. Neurosci. Res , vol.84 , Issue.3 , pp. 553-567
    • Abdellatif, A.A.1    Pelt, J.L.2    Benton, R.L.3    Howard, R.M.4    Tsoulfas, P.5    Ping, P.6    Xu, X.M.7    Whittemore, S.R.8
  • 237
    • 34848866015 scopus 로고    scopus 로고
    • Transient growth factor delivery sustains regenerated axons after spinal cord injury
    • Blesch A.; Tuszynski M. H. Transient growth factor delivery sustains regenerated axons after spinal cord injury. J. Neurosci., 2007, 27(39), 10535-10545.
    • (2007) J. Neurosci , vol.27 , Issue.39 , pp. 10535-10545
    • Blesch, A.1    Tuszynski, M.H.2
  • 238
    • 22044444565 scopus 로고    scopus 로고
    • Effects of root replantation and neurotrophic factor treatment on long-term motoneuron survival and axonal regeneration after C7 spinal root avulsion
    • Lang E. M.; Schlegel N.; Sendtner M.; Asan E. Effects of root replantation and neurotrophic factor treatment on long-term motoneuron survival and axonal regeneration after C7 spinal root avulsion. Exp. Neurol., 2005, 194(2), 341-354.
    • (2005) Exp. Neurol , vol.194 , Issue.2 , pp. 341-354
    • Lang, E.M.1    Schlegel, N.2    Sendtner, M.3    Asan, E.4
  • 239
    • 33746737393 scopus 로고    scopus 로고
    • Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold
    • Garreta E.; Genove E.; Borros S.; Semino C. E. Osteogenic differentiation of mouse embryonic stem cells and mouse embryonic fibroblasts in a three-dimensional self-assembling peptide scaffold. Tissue Eng., 2006, 12(8), 2215-2227.
    • (2006) Tissue Eng , vol.12 , Issue.8 , pp. 2215-2227
    • Garreta, E.1    Genove, E.2    Borros, S.3    Semino, C.E.4
  • 240
  • 241
    • 1842504073 scopus 로고    scopus 로고
    • Semaphorin and neuropilin expression in motoneurons after intraspinal motoneuron axotomy
    • Lindholm T.; Skold M. K.; Suneson A.; Carlstedt T.; Cullheim S.; Risling M. Semaphorin and neuropilin expression in motoneurons after intraspinal motoneuron axotomy. Neuroreport, 2004, 15(4), 649-654.
    • (2004) Neuroreport , vol.15 , Issue.4 , pp. 649-654
    • Lindholm, T.1    Skold, M.K.2    Suneson, A.3    Carlstedt, T.4    Cullheim, S.5    Risling, M.6
  • 242
    • 0033553253 scopus 로고    scopus 로고
    • GDNF, RET and GFRalpha-1-3 mRNA expression in the developing human spinal cord and ganglia
    • Widenfalk J.; Widmer H. R.; Spenger C. GDNF, RET and GFRalpha-1-3 mRNA expression in the developing human spinal cord and ganglia. Neuroreport, 1999, 10(7), 1433-1439.
    • (1999) Neuroreport , vol.10 , Issue.7 , pp. 1433-1439
    • Widenfalk, J.1    Widmer, H.R.2    Spenger, C.3


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