메뉴 건너뛰기




Volumn 25, Issue 4, 2005, Pages 371-380

Peripheral nerve avulsion injuries as experimental models for adult motoneuron degeneration

Author keywords

Adenovirus; Avulsion; Facial nerve; Motoneuron; Neurotrophic factor

Indexed keywords

1 (BENZO[B]THIEN 5 YL) 2 (2 DIETHYLAMINOETHOXY)ETHANOL; ADENOVIRUS VECTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLINE ACETYLTRANSFERASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; GROWTH INHIBITOR; NEUROPROTECTIVE AGENT; NITRIC OXIDE SYNTHASE; TRANSFORMING GROWTH FACTOR BETA2; DIETHYLAMINE; NERVE PROTEIN; THIOPHENE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA;

EID: 33644817653     PISSN: 09196544     EISSN: 14401789     Source Type: Journal    
DOI: 10.1111/j.1440-1789.2005.00609.x     Document Type: Conference Paper
Times cited : (24)

References (66)
  • 1
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • Cleveland DW Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001 2 : 806 819.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 2
    • 0019518202 scopus 로고
    • Variations in the axon reaction after different types of nerve lesion
    • Søreide AJ. Variations in the axon reaction after different types of nerve lesion. Acta Anat 1981 110 : 173 188.
    • (1981) Acta Anat , vol.110 , pp. 173-188
    • Søreide, A.J.1
  • 3
    • 0027154946 scopus 로고
    • Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry
    • Wu W. Expression of nitric-oxide synthase (NOS) in injured CNS neurons as shown by NADPH diaphorase histochemistry. Exp Neurol 1993 120 : 153 159.
    • (1993) Exp Neurol , vol.120 , pp. 153-159
    • Wu, W.1
  • 4
    • 0028269017 scopus 로고
    • Ventral root avulsion: An experimental model of death of adult motor neurons
    • Koliatsos VE Price WL Pardo CA Price DL. Ventral root avulsion: an experimental model of death of adult motor neurons. J Comp Neurol 1994 342 : 35 44.
    • (1994) J Comp Neurol , vol.342 , pp. 35-44
    • Koliatsos, V.E.1    Price, W.L.2    Pardo, C.A.3    Price, D.L.4
  • 5
    • 0034657174 scopus 로고    scopus 로고
    • Rescue of lesioned adult rat spinal motoneurons by adenoviral gene transfer of glial cell line-derived neurotrophic factor
    • Watabe K Ohashi T Sakamoto T et al. Rescue of lesioned adult rat spinal motoneurons by adenoviral gene transfer of glial cell line-derived neurotrophic factor. J Neurosci Res 2000 60 : 511 519.
    • (2000) J Neurosci Res , vol.60 , pp. 511-519
    • Watabe, K.1    Ohashi, T.2    Sakamoto, T.3
  • 6
    • 0034717679 scopus 로고    scopus 로고
    • Adenoviral vector-mediated GDNF gene transfer prevents death of adult facial motoneurons
    • Sakamoto T Watabe K Ohashi T et al. Adenoviral vector-mediated GDNF gene transfer prevents death of adult facial motoneurons. Neuroreport 2000 11 : 1857 1860.
    • (2000) Neuroreport , vol.11 , pp. 1857-1860
    • Sakamoto, T.1    Watabe, K.2    Ohashi, T.3
  • 7
    • 0035291107 scopus 로고    scopus 로고
    • Adenoviral gene transfer of glial cell line-derived neurotrophic factor to injured adult motoneurons
    • Watabe K Sakamoto T Ohashi T et al. Adenoviral gene transfer of glial cell line-derived neurotrophic factor to injured adult motoneurons. Hum Cell 2001 14 : 7 15.
    • (2001) Hum Cell , vol.14 , pp. 7-15
    • Watabe, K.1    Sakamoto, T.2    Ohashi, T.3
  • 9
    • 0037381513 scopus 로고    scopus 로고
    • Adenoviral gene transfer of GDNF, BDNF and TGFβ2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion
    • Sakamoto T Kawazoe Y Shen JS et al. Adenoviral gene transfer of GDNF, BDNF and TGFβ2, but not CNTF, cardiotrophin-1 or IGF1, protects injured adult motoneurons after facial nerve avulsion. J Neurosci Res 2003 72 : 54 64.
    • (2003) J Neurosci Res , vol.72 , pp. 54-64
    • Sakamoto, T.1    Kawazoe, Y.2    Shen, J.S.3
  • 10
    • 85026146143 scopus 로고    scopus 로고
    • Growth inhibitory factor prevents degeneration of injured adult rat motoneurons
    • Sakamoto T Kawazoe Y Uchida Y Hozumi I Inuzuka T Watabe K. Growth inhibitory factor prevents degeneration of injured adult rat motoneurons. Neuroreport 2003 14 : 2147 2151.
    • (2003) Neuroreport , vol.14 , pp. 2147-2151
    • Sakamoto, T.1    Kawazoe, Y.2    Uchida, Y.3    Hozumi, I.4    Inuzuka, T.5    Watabe, K.6
  • 11
    • 0038107466 scopus 로고    scopus 로고
    • Oral administration of a neuroprotective compound T-588 prevents motoneuron degeneration after facial nerve avulsion in adult rats
    • Ikeda K Sakamoto T Kawazoe Y et al. Oral administration of a neuroprotective compound T-588 prevents motoneuron degeneration after facial nerve avulsion in adult rats. Amyotroph Lateral Scler Other Motor Neuron Disord 2003 4 : 74 80.
    • (2003) Amyotroph Lateral Scler Other Motor Neuron Disord , vol.4 , pp. 74-80
    • Ikeda, K.1    Sakamoto, T.2    Kawazoe, Y.3
  • 12
    • 0037423054 scopus 로고    scopus 로고
    • Adenoviral GDNF gene transfer prevents motoneuron loss in the nucleus ambiguus
    • Saito K Shiotani A Watabe K Moro K Fukuda H Ogawa K. Adenoviral GDNF gene transfer prevents motoneuron loss in the nucleus ambiguus. Brain Res 2003 962 : 61 67.
    • (2003) Brain Res , vol.962 , pp. 61-67
    • Saito, K.1    Shiotani, A.2    Watabe, K.3    Moro, K.4    Fukuda, H.5    Ogawa, K.6
  • 13
    • 0032864716 scopus 로고    scopus 로고
    • Motor neuron degeneration after nerve avulsion in adult evolves with oxidative stress and is apoptosis
    • Martin LJ Kaiser A Price AC. Motor neuron degeneration after nerve avulsion in adult evolves with oxidative stress and is apoptosis. J Neurobiol 1999 40 : 185 201.
    • (1999) J Neurobiol , vol.40 , pp. 185-201
    • Martin, L.J.1    Kaiser, A.2    Price, A.C.3
  • 14
    • 0031773432 scopus 로고    scopus 로고
    • Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
    • Estévez AG Spear N Manuel SM Barbeito L Radi R Beckman JS. Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Prog Brain Res 1998 118 : 269 280.
    • (1998) Prog Brain Res , vol.118 , pp. 269-280
    • Estévez, A.G.1    Spear, N.2    Manuel, S.M.3    Barbeito, L.4    Radi, R.5    Beckman, J.S.6
  • 15
    • 0033231494 scopus 로고    scopus 로고
    • From Charcot to SOD1: Mechanisms of selective motor neuron death in ALS
    • Cleveland DW. From Charcot to SOD1: mechanisms of selective motor neuron death in ALS. Neuron 1999 24 : 515 520.
    • (1999) Neuron , vol.24 , pp. 515-520
    • Cleveland, D.W.1
  • 16
    • 0029962130 scopus 로고    scopus 로고
    • Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice
    • de Bilbao F Dubois-Dauphin M. Time course of axotomy-induced apoptotic cell death in facial motoneurons of neonatal wild type and bcl-2 transgenic mice. Neuroscience 1996 71 : 1111 1119.
    • (1996) Neuroscience , vol.71 , pp. 1111-1119
    • De Bilbao, F.1    Dubois-Dauphin, M.2
  • 17
    • 0029967866 scopus 로고    scopus 로고
    • Axotomy-induced apoptotic cell death of neonatal rat facial motoneurons: Time course analysis and relation to NADPH-diaphorase activity
    • Rossiter JP Riopelle RJ Bisby MA. Axotomy-induced apoptotic cell death of neonatal rat facial motoneurons: time course analysis and relation to NADPH-diaphorase activity. Exp Neurol 1996 138 : 33 44.
    • (1996) Exp Neurol , vol.138 , pp. 33-44
    • Rossiter, J.P.1    Riopelle, R.J.2    Bisby, M.A.3
  • 19
    • 0033788397 scopus 로고    scopus 로고
    • Caspase-3 is activated following axotomy of neonatal facial motoneurons and caspase-3 gene deletion delays axotomy-induced cell death in rodents
    • Vanderluit JL McPhail LT Fernandes KJ et al. Caspase-3 is activated following axotomy of neonatal facial motoneurons and caspase-3 gene deletion delays axotomy-induced cell death in rodents. Eur J Neurosci 2000 12 : 3469 3480.
    • (2000) Eur J Neurosci , vol.12 , pp. 3469-3480
    • Vanderluit, J.L.1    McPhail, L.T.2    Fernandes, K.J.3
  • 20
    • 0026507555 scopus 로고
    • Dependence of postnatal motoneurones on their targets: Review and hypothesis
    • Lowrie MB Vrbová G. Dependence of postnatal motoneurones on their targets: review and hypothesis. Trend Neurosci 1992 15 : 80 84.
    • (1992) Trend Neurosci , vol.15 , pp. 80-84
    • Lowrie, M.B.1    Vrbová, G.2
  • 21
    • 1442299203 scopus 로고    scopus 로고
    • The facial nerve axotomy model
    • Moran LB Graeber MB. The facial nerve axotomy model. Brain Res Rev 2004 44 : 154 178.
    • (2004) Brain Res Rev , vol.44 , pp. 154-178
    • Moran, L.B.1    Graeber, M.B.2
  • 22
    • 0037083204 scopus 로고    scopus 로고
    • Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent
    • Martin LJ Liu Z. Injury-induced spinal motor neuron apoptosis is preceded by DNA single-strand breaks and is p53- and Bax-dependent. J Neurobiol 2002 50 : 181 197.
    • (2002) J Neurobiol , vol.50 , pp. 181-197
    • Martin, L.J.1    Liu, Z.2
  • 23
    • 0032578036 scopus 로고    scopus 로고
    • Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice
    • Li L Houenou LJ Wu W Lei M Prevette DM Oppenheim RW. Characterization of spinal motoneuron degeneration following different types of peripheral nerve injury in neonatal and adult mice. J Comp Neurol 1998 396 : 158 168.
    • (1998) J Comp Neurol , vol.396 , pp. 158-168
    • Li, L.1    Houenou, L.J.2    Wu, W.3    Lei, M.4    Prevette, D.M.5    Oppenheim, R.W.6
  • 24
    • 0036019165 scopus 로고    scopus 로고
    • Mechanisms of cell death in neurodegenerative diseases: Fashion, fiction, and facts
    • Graeber MB Moran LB. Mechanisms of cell death in neurodegenerative diseases: fashion, fiction, and facts. Brain Pathol 2002 12 : 385 390.
    • (2002) Brain Pathol , vol.12 , pp. 385-390
    • Graeber, M.B.1    Moran, L.B.2
  • 25
    • 0035068196 scopus 로고    scopus 로고
    • Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion
    • Yamada M Natsume A Mata M et al. Herpes simplex virus vector-mediated expression of Bcl-2 protects spinal motor neurons from degeneration following root avulsion. Exp Neurol 2001 168 : 225 230.
    • (2001) Exp Neurol , vol.168 , pp. 225-230
    • Yamada, M.1    Natsume, A.2    Mata, M.3
  • 26
    • 0035809758 scopus 로고    scopus 로고
    • Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats
    • Chan Y-M Wu W Yip HK So K-F Oppenheim RW. Caspase inhibitors promote the survival of avulsed spinal motoneurons in neonatal rats. Neuroreport 2001 12 : 541 545.
    • (2001) Neuroreport , vol.12 , pp. 541-545
    • Chan, Y.-M.1    Wu, W.2    Yip, H.K.3    So, K.-F.4    Oppenheim, R.W.5
  • 27
    • 0028815823 scopus 로고
    • Neuron saving schemes
    • Lindsay RM. Neuron saving schemes. Nature 1995 373 : 289 290.
    • (1995) Nature , vol.373 , pp. 289-290
    • Lindsay, R.M.1
  • 28
    • 0030220893 scopus 로고    scopus 로고
    • Neurotrophic suvival molecules for motoneurons: An embarrassment of riches
    • Oppenheim RW. Neurotrophic suvival molecules for motoneurons: an embarrassment of riches. Neuron 1996 17 : 195 197.
    • (1996) Neuron , vol.17 , pp. 195-197
    • Oppenheim, R.W.1
  • 29
    • 1842329729 scopus 로고    scopus 로고
    • Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons
    • Gravel C Götz R Lorrain A Sendtner M. Adenoviral gene transfer of ciliary neurotrophic factor and brain-derived neurotrophic factor leads to long-term survival of axotomized motor neurons. Nature Med 1997 3 : 765 770.
    • (1997) Nature Med , vol.3 , pp. 765-770
    • Gravel, C.1    Götz, R.2    Lorrain, A.3    Sendtner, M.4
  • 31
    • 0030763998 scopus 로고    scopus 로고
    • Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factors genes confers neuroprotection that exceeds the transduced population
    • Baumgartner BJ Shine HD. Targeted transduction of CNS neurons with adenoviral vectors carrying neurotrophic factors genes confers neuroprotection that exceeds the transduced population. J Neurosci 1997 17 : 6504 6511.
    • (1997) J Neurosci , vol.17 , pp. 6504-6511
    • Baumgartner, B.J.1    Shine, H.D.2
  • 32
    • 0031687457 scopus 로고    scopus 로고
    • Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell line-derived neurotrophic factor
    • Baumgartner BJ Shine HD. Neuroprotection of spinal motoneurons following targeted transduction with an adenoviral vector carrying the gene for glial cell line-derived neurotrophic factor. Exp Neurol 1998 153 : 102 112.
    • (1998) Exp Neurol , vol.153 , pp. 102-112
    • Baumgartner, B.J.1    Shine, H.D.2
  • 33
    • 0030953519 scopus 로고    scopus 로고
    • Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors
    • Haase G Kennel P Pettmann B et al. Gene therapy of murine motor neuron disease using adenoviral vectors for neurotrophic factors. Nature Med 1997 3 : 429 436.
    • (1997) Nature Med , vol.3 , pp. 429-436
    • Haase, G.1    Kennel, P.2    Pettmann, B.3
  • 34
    • 0032699093 scopus 로고    scopus 로고
    • Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuropathy
    • Bordet T Schmalbruch H Pettmann B et al. Adenoviral cardiotrophin-1 gene transfer protects pmn mice from progressive motor neuropathy. J Clin Invest 1999 104 : 1077 1085.
    • (1999) J Clin Invest , vol.104 , pp. 1077-1085
    • Bordet, T.1    Schmalbruch, H.2    Pettmann, B.3
  • 35
    • 0028822549 scopus 로고
    • Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor
    • Li L Wu W Lin L-FH Lei M Oppenheim RW Houenou LJ. Rescue of adult mouse motoneurons from injury-induced cell death by glial cell line-derived neurotrophic factor. Proc Natl Acad Sci USA 1995 92 : 9771 9775.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 9771-9775
    • Li, L.1    Wu, W.2    L-Fh, L.3    Lei, M.4    Oppenheim, R.W.5    Houenou, L.J.6
  • 36
    • 0028853885 scopus 로고
    • Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion
    • Novikov L Novikova L Kellerth JO. Brain-derived neurotrophic factor promotes survival and blocks nitric oxide synthase expression in adult rat spinal motoneurons after ventral root avulsion. Neurosci Lett 1995 200 : 45 48.
    • (1995) Neurosci Lett , vol.200 , pp. 45-48
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 37
    • 0030762723 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo
    • Novikov L Novikova L Kellerth JO. Brain-derived neurotrophic factor promotes axonal regeneration and long-term survival of adult rat spinal motoneurons in vivo. Neuroscience 1997 79 : 765 774.
    • (1997) Neuroscience , vol.79 , pp. 765-774
    • Novikov, L.1    Novikova, L.2    Kellerth, J.O.3
  • 38
    • 0031128211 scopus 로고    scopus 로고
    • BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
    • Kishino A Ishige Y Tatsuno T Nakayama C Noguchi H. BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth. Exp Neurol 1997 144 : 273 286.
    • (1997) Exp Neurol , vol.144 , pp. 273-286
    • Kishino, A.1    Ishige, Y.2    Tatsuno, T.3    Nakayama, C.4    Noguchi, H.5
  • 39
    • 0032873649 scopus 로고    scopus 로고
    • Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat
    • Chai H Wu W So KF Prevette DM Oppenheim RW. Long-term effects of a single dose of brain-derived neurotrophic factor on motoneuron survival following spinal root avulsion in the adult rat. Neurosci Lett 1999 274 : 147 150.
    • (1999) Neurosci Lett , vol.274 , pp. 147-150
    • Chai, H.1    Wu, W.2    So, K.F.3    Prevette, D.M.4    Oppenheim, R.W.5
  • 40
    • 0034672198 scopus 로고    scopus 로고
    • TGF-β2 attenuates the injury-induced death of mature motoneurons
    • Jiang Y Zhang M Koishi K McLennan IS. TGF-β2 attenuates the injury-induced death of mature motoneurons. J Neurosci Res 2002 62 : 809 813.
    • (2002) J Neurosci Res , vol.62 , pp. 809-813
    • Jiang, Y.1    Zhang, M.2    Koishi, K.3    McLennan, I.S.4
  • 41
    • 0030070724 scopus 로고    scopus 로고
    • Efficient generation of recombinant adenovirus using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome
    • Miyake S Makimura M Kanegae Y et al. Efficient generation of recombinant adenovirus using adenovirus DNA-terminal protein complex and a cosmid bearing the full-length virus genome. Proc Natl Acad Sci USA 1996 93 : 1320 1324.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 1320-1324
    • Miyake, S.1    Makimura, M.2    Kanegae, Y.3
  • 42
    • 0028799961 scopus 로고
    • Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase
    • Kanegae Y Lee G Sato Y et al. Efficient gene activation in mammalian cells by using recombinant adenovirus expressing site-specific Cre recombinase. Nucl Acid Res 1995 23 : 3816 3821.
    • (1995) Nucl Acid Res , vol.23 , pp. 3816-3821
    • Kanegae, Y.1    Lee, G.2    Sato, Y.3
  • 43
    • 0028021025 scopus 로고
    • Mitogenic effects of platelet-derived growth factor, fibroblast growth factor, transforming growth factor-β, and heparin-binding serum factor for adult mouse Schwann cells
    • Watabe K Fukuda T Tanaka J Toyohara K Sakai O. Mitogenic effects of platelet-derived growth factor, fibroblast growth factor, transforming growth factor-β, and heparin-binding serum factor for adult mouse Schwann cells. J Neurosci Res 1994 39 : 525 534.
    • (1994) J Neurosci Res , vol.39 , pp. 525-534
    • Watabe, K.1    Fukuda, T.2    Tanaka, J.3    Toyohara, K.4    Sakai, O.5
  • 44
    • 0029059942 scopus 로고
    • Spontaneously immortalized adult mouse Schwann cells secrete autocrine and paracrine growth-promoting activities
    • Watabe K Fukuda T Tanaka J Honda H Toyohara K Sakai O. Spontaneously immortalized adult mouse Schwann cells secrete autocrine and paracrine growth-promoting activities. J Neurosci Res 1995 41 : 279 290.
    • (1995) J Neurosci Res , vol.41 , pp. 279-290
    • Watabe, K.1    Fukuda, T.2    Tanaka, J.3    Honda, H.4    Toyohara, K.5    Sakai, O.6
  • 45
    • 0037354956 scopus 로고    scopus 로고
    • Tissue culture methods to study neurological disorders: Establishment of immortalized Schwann cells from murine disease models
    • Watabe K Sakamoto T Kawazoe Y et al. Tissue culture methods to study neurological disorders: establishment of immortalized Schwann cells from murine disease models. Neuropathology 2003 23 : 64 74.
    • (2003) Neuropathology , vol.23 , pp. 64-74
    • Watabe, K.1    Sakamoto, T.2    Kawazoe, Y.3
  • 46
    • 0029555820 scopus 로고
    • Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neuron diseases
    • Finiels F Gimenez y Ribotta M Barkats M et al. Specific and efficient gene transfer strategy offers new potentialities for the treatment of motor neuron diseases. Neuroreport 1995 7 : 373 378.
    • (1995) Neuroreport , vol.7 , pp. 373-378
    • Finiels, F.1    Gimenez Ribotta, Y.M.2    Barkats, M.3
  • 47
    • 0028965811 scopus 로고
    • CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses
    • Ghadge GD Roos RP Kang UJ et al. CNS gene delivery by retrograde transport of recombinant replication-defective adenoviruses. Gene Ther 1995 2 : 132 137.
    • (1995) Gene Ther , vol.2 , pp. 132-137
    • Ghadge, G.D.1    Roos, R.P.2    Kang, U.J.3
  • 48
    • 0028854836 scopus 로고
    • In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
    • Yan Q Matheson C Lopez OT. In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons. Nature 1995 373 : 341 344.
    • (1995) Nature , vol.373 , pp. 341-344
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3
  • 49
    • 0027969192 scopus 로고
    • The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor
    • Yan Q Matheson C Lopez OT Miller JA. The biological responses of axotomized adult motoneurons to brain-derived neurotrophic factor. J Neurosci 1994 14 : 5281 5291.
    • (1994) J Neurosci , vol.14 , pp. 5281-5291
    • Yan, Q.1    Matheson, C.2    Lopez, O.T.3    Miller, J.A.4
  • 50
    • 0028825290 scopus 로고
    • The role of nitric oxide in facial motoneuronal death
    • Ruan R-S Leong S-K Yeoh K-H. The role of nitric oxide in facial motoneuronal death. Brain Res 1995 698 : 163 168.
    • (1995) Brain Res , vol.698 , pp. 163-168
    • Ruan, R.-S.1    Leong, S.-K.2    Yeoh, K.-H.3
  • 51
    • 0027157901 scopus 로고
    • Inhibition of nitric oxide synthase reduces motoneuron death due to spinal root avulsion
    • Wu W Li L. Inhibition of nitric oxide synthase reduces motoneuron death due to spinal root avulsion. Neurosci Lett 1993 153 : 121 124.
    • (1993) Neurosci Lett , vol.153 , pp. 121-124
    • Wu, W.1    Li, L.2
  • 52
    • 0029965068 scopus 로고    scopus 로고
    • Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro
    • Zurn AD Winkel L Menoud A Djabali K Aebischer P. Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro. J Neurosci Res 1996 44 : 133 141.
    • (1996) J Neurosci Res , vol.44 , pp. 133-141
    • Zurn, A.D.1    Winkel, L.2    Menoud, A.3    Djabali, K.4    Aebischer, P.5
  • 53
    • 0025768860 scopus 로고
    • The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
    • Uchida Y Takio K Titani K Ihara Y Tomonaga M. The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron 1991 7 : 337 347.
    • (1991) Neuron , vol.7 , pp. 337-347
    • Uchida, Y.1    Takio, K.2    Titani, K.3    Ihara, Y.4    Tomonaga, M.5
  • 54
    • 0034047740 scopus 로고    scopus 로고
    • Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons
    • Montoliu C Monfort P Carrasco J et al. Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons. J Neurochem 2000 75 : 266 273.
    • (2000) J Neurochem , vol.75 , pp. 266-273
    • Montoliu, C.1    Monfort, P.2    Carrasco, J.3
  • 55
    • 0035814479 scopus 로고    scopus 로고
    • Different protective roles in vitro of α- And β-domains of growth inhibitory factor (GIF) on neuron injuries caused by oxygen free radicals
    • Ren H Ji Q Liu Y Ru B. Different protective roles in vitro of α- and β-domains of growth inhibitory factor (GIF) on neuron injuries caused by oxygen free radicals. Biochim Biophys Acta 2001 1568 : 129 134.
    • (2001) Biochim Biophys Acta , vol.1568 , pp. 129-134
    • Ren, H.1    Ji, Q.2    Liu, Y.3    Ru, B.4
  • 56
    • 0037200013 scopus 로고    scopus 로고
    • Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging
    • Uchida Y Gomi F Masumizu T Miura Y. Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging. J Biol Chem 2002 277 : 32353 32359.
    • (2002) J Biol Chem , vol.277 , pp. 32353-32359
    • Uchida, Y.1    Gomi, F.2    Masumizu, T.3    Miura, Y.4
  • 57
    • 18744409323 scopus 로고    scopus 로고
    • Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords - Screening by molecular indexing and subsequent cDNA microarray analysis
    • Ishigaki S Niwa J Ando Y et al. Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords - screening by molecular indexing and subsequent cDNA microarray analysis. FEBS Lett 2002 531 : 354 358.
    • (2002) FEBS Lett , vol.531 , pp. 354-358
    • Ishigaki, S.1    Niwa, J.2    Ando, Y.3
  • 58
    • 0011392304 scopus 로고    scopus 로고
    • Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis
    • Gong YH Elliott JL. Metallothionein expression is altered in a transgenic murine model of familial amyotrophic lateral sclerosis. Exp Neurol 2000 162 : 27 36.
    • (2000) Exp Neurol , vol.162 , pp. 27-36
    • Gong, Y.H.1    Elliott, J.L.2
  • 60
    • 0037109771 scopus 로고    scopus 로고
    • Disease progression in transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins
    • Puttaparthi K Gitomer WL Krishnan U Son M Rajendran B Elliott JL. Disease progression in transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins. J Neurosci 2002 22 : 8790 8796.
    • (2002) J Neurosci , vol.22 , pp. 8790-8796
    • Puttaparthi, K.1    Gitomer, W.L.2    Krishnan, U.3    Son, M.4    Rajendran, B.5    Elliott, J.L.6
  • 61
    • 0030833449 scopus 로고    scopus 로고
    • Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite
    • Crow JP Sampson JB Zhuang Y Thompson JA Beckman JS. Decreased zinc affinity of amyotrophic lateral sclerosis-associated superoxide dismutase mutants leads to enhanced catalysis of tyrosine nitration by peroxynitrite. J Neurochem 1997 69 : 1936 1944.
    • (1997) J Neurochem , vol.69 , pp. 1936-1944
    • Crow, J.P.1    Sampson, J.B.2    Zhuang, Y.3    Thompson, J.A.4    Beckman, J.S.5
  • 62
    • 0039251419 scopus 로고    scopus 로고
    • Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase
    • Estévez AG Crow JP Sampson JB et al. Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science 1999 286 : 2498 2500.
    • (1999) Science , vol.286 , pp. 2498-2500
    • Estévez, A.G.1    Crow, J.P.2    Sampson, J.B.3
  • 63
    • 0027297787 scopus 로고
    • Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(N,N- diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia
    • Ono S Kitamura K Maekawa M et al. Protective effect of R(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(N,N-diethylamino)ethoxy]ethanol hydrochloride (T-588), a novel cerebral activator, against experimental cerebral anoxia. Jpn J Pharmacol 1993 62 : 81 86.
    • (1993) Jpn J Pharmacol , vol.62 , pp. 81-86
    • Ono, S.1    Kitamura, K.2    Maekawa, M.3
  • 64
    • 0033965941 scopus 로고    scopus 로고
    • T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease
    • Ikeda K Iwasaki Y Kinoshita M Marubuchi S Ono S. T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease. Brain Res 2000 858 : 84 91.
    • (2000) Brain Res , vol.858 , pp. 84-91
    • Ikeda, K.1    Iwasaki, Y.2    Kinoshita, M.3    Marubuchi, S.4    Ono, S.5
  • 65
    • 0036208503 scopus 로고    scopus 로고
    • T-588 enhances neurite outgrowth and choline acetyltransferase in cultured rat spinal ventral horn neurons
    • Iwasaki Y Ikeda K Ichikawa Y et al. T-588 enhances neurite outgrowth and choline acetyltransferase in cultured rat spinal ventral horn neurons. Neurochem Res 2002 27 : 225 228.
    • (2002) Neurochem Res , vol.27 , pp. 225-228
    • Iwasaki, Y.1    Ikeda, K.2    Ichikawa, Y.3
  • 66
    • 0034733797 scopus 로고    scopus 로고
    • T-588 inhibits astrocyte apoptosis via mitogen activated protein kinase signal pathway
    • Takuma K Fujita T Kimura Y et al. T-588 inhibits astrocyte apoptosis via mitogen activated protein kinase signal pathway. Eur J Pharmacol 2000 399 : 1 8.
    • (2000) Eur J Pharmacol , vol.399 , pp. 1-8
    • Takuma, K.1    Fujita, T.2    Kimura, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.