IGF-I prevents glutamate-induced motor neuron programmed cell death

Neurobiology of Disease

Volumn 16, Issue 2, 2004, Pages 407-416

  Vincent, Andrea M ^a   Mobley, Bret C ^a   Hiller, Andrew ^a   Feldman, Eva L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Apoptosis; Drug screening; Gene therapy; Insulin like growth factor I; Programmed cell death (PCD); Signal transduction; Terminal deoxy UTP nicked end labeling

Indexed keywords

CASPASE 3; DNA FRAGMENT; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN C DERIVATIVE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL TISSUE; ARTICLE; CELL SURVIVAL; CEREBROSPINAL FLUID; CONTROLLED STUDY; DISEASE MODEL; DOSE TIME EFFECT RELATION; EMBRYO; MOTONEURON; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR BINDING; RECEPTOR BLOCKING;

ANIMALS; APOPTOSIS; CASPASES; CELLS, CULTURED; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FETUS; GLUTAMIC ACID; INSULIN-LIKE GROWTH FACTOR I; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOTOR NEURONS; NEUROPROTECTIVE AGENTS; PHOSPHOPROTEINS; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPINAL CORD;

EID: 2942695980     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2004.03.001     Document Type: Article

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