Leukemia inhibitory factor is a myotrophic and neurotrophic agent that enhances the reinnervation of muscle in the rat

Journal of Neuroscience Research

Volumn 46, Issue 1, 1996, Pages 122-128

  Finkelstein, D I ^a   Bartlett, P F ^c   Horne, M K ^a,b   Cheema, S S ^a  

^a MONASH UNIVERSITY   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

atrophy; growth factors; muscle; peripheral nerves; reinnervation

Indexed keywords

LEUKEMIA INHIBITORY FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GASTROCNEMIUS MUSCLE; MUSCLE ATROPHY; MUSCLE DENERVATION; MUSCLE REINNERVATION; NERVE FIBER; NEUROTROPISM; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; GROWTH INHIBITORS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LYMPHOKINES; MALE; MUSCLE DENERVATION; MUSCLE DEVELOPMENT; MUSCLE, SKELETAL; NERVE CRUSH; NERVE REGENERATION; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0029782556     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19961001)46:1<122::AID-JNR15>3.0.CO;2-7     Document Type: Article

References (15)

1. Anzil AP, Wernig A (1989): Muscle fibre loss and reinnervation after long-term denervation. J Neurocytol 18:833-845.
2. Austin L, Bower J, Kurek J, Vakakis N (1992): Effects of leukaemia inhibitory factor and other cytokines on murine and human myoblast proliferation. J Neurol Sci 112:185-191.
3. Barnard W, Bower J, Brown MA, Murphy M, Austin L (1994): Leukemia inhibitory factor (LIF) infusion stimulates skeletal muscle regeneration after injury: Injured muscle expresses lif mRNA. J Neurol Sci 123:108-113.
4. Cheema SS, Richards LJ, Murphy M, Bartlett PF (1994): Leukaemia inhibitory factor rescues motoneurones from axotomy-induced cell death. Neuroreport 5:989-992.
5. Curtis R, Scherer SS, Somogyi R, Adryan KM, Ip NY, Zhu Y, Lindsay RM, DiStefano PS (1994): Retrograde axonal transport of LIF is increased by peripheral nerve injury: Correlation with increased LIF expression in distal nerve. Neuron 12:191-204.
6. Finkelstein DI, Dooley PC, Luff AR (1993): Recovery of muscle after different periods of denervation and treatments. Muscle Nerve 16:769-777.
7. Gurney ME, Yamamoto H, Kwon Y (1992): Induction of motor neuron sprouting in vivo by ciliary neurotrophic factor and basic fibroblast growth factor. J Neurosci 12:3241-3247.
8. Gutmann E, Sanders FK (1943): Recovery of fibre numbers and diameters in the regeneration of peripheral nerves. J Physiol 101: 489-518.
9. Helgren ME, Squinto SP, Davis HL, Parry DJ, Boulton TG, Heck CS, Zhu Y, Yancopoulos GD, Lindsay RM, DiStefano PS (1994): Trophic effect of ciliary neurotrophic factor on denervated skeletal muscle. Cell 76:493-504.
10. Hendry IA, Murphy M, Hilton DJ, Nicola NA, Bartlett PF (1992): Binding and retrograde transport of luekemia inhibitory factor by the sensory nervous system. J Neurosci 12:3427-3434.
11. Hughes RA, Sendtner M, Thoenen H (1993): Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J Neurosci Res 36:663-671.
12. Ip NY, Nye SH, Boulton TG, Davis S, Taga T, Li Y, Birren SJ, Yasukawa K, Kishimoto T, Anderson DJ, Stahl N, Yancoupoulos GD (1992): CNTF and LIF act on neuronal cells via shared signaling pathways that involve the IL-6 signal transducing receptor component gp130. Cell 69:1121-1132.
13. Kugelberg E, Edstrom L, Abbruzzese M (1970): Mapping of motor units in experimentally reinnervated rat muscle. Interpretation of histochemical and atrophic fibre patterns in neurogenic lesions. J Neurol Neurosurg Psychiat 33:319-329.
14. Metcalf D, Gearing DP (1989): Fatal syndrome in mice engrafted with cells producing high levels of the leukemia inhibitory factor. Proc Natl Acad Sci USA 86:5948-5952.
15. Simons M, Edelman ER, Rosenberg RD (1994): Antisense proliferating cell nuclear antigen oligonucleotides inhibit hyperplasia in a rat carotid artery injury model. J Clin Invest 93:2351-2356.